Current Appointments & Affiliations
Consulting Professor in the Department of Medicine
·
2018 - Present
Medicine, Cardiology,
Medicine
Recent Publications
A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
Journal Article J Mol Biol · February 14, 2020 Three of six arginine codons (CGU, CGC, and CGA) are decoded by two Escherichia coli tRNAArg isoacceptors. The anticodon stem and loop (ASL) domains of tRNAArg1 and tRNAArg2 both contain inosine and 2-methyladenosine modifications at positions 34 (I34) and ... Full text Link to item CiteRecent Grants
Biochemical Consequences of Cdka I I Mutation that Result in Unprocessed, Nonfunctional Insulin and Type 2 Diabetes
ResearchPrincipal Investigator · Awarded by Department of Defense · 2016 - 2021Sequence selective recognition of double stranded non-coding RNA
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2018 - 2020View All Grants
Education, Training & Certifications
Massachusetts Institute of Technology ·
1971
Ph.D.
Bucknell University ·
1966
B.S.