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Paul F. Agris

Consulting Professor in the Department of Medicine
Medicine, Cardiology
203 Research Drive, DUMC 2647, Durham, NC 27710
203 Research Drive, DUMC 2647, Durham, NC 27710

Current Appointments & Affiliations


Consulting Professor in the Department of Medicine · 2018 - Present Medicine, Cardiology, Medicine

Recent Publications


A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.

Journal Article J Mol Biol · February 14, 2020 Three of six arginine codons (CGU, CGC, and CGA) are decoded by two Escherichia coli tRNAArg isoacceptors. The anticodon stem and loop (ASL) domains of tRNAArg1 and tRNAArg2 both contain inosine and 2-methyladenosine modifications at positions 34 (I34) and ... Full text Link to item Cite
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Recent Grants


Biochemical Consequences of Cdka I I Mutation that Result in Unprocessed, Nonfunctional Insulin and Type 2 Diabetes

ResearchPrincipal Investigator · Awarded by Department of Defense · 2016 - 2021

Sequence selective recognition of double stranded non-coding RNA

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2018 - 2020

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Education, Training & Certifications


Massachusetts Institute of Technology · 1971 Ph.D.
Bucknell University · 1966 B.S.