Scholars@Duke
Paul James Clark

Paul James Clark

Adjunct Associate in the Department of Medicine
Medicine, Gastroenterology
paul.clark@duke.edu
2400 Pratt Street, Box 3850, Durham, NC 27710

Scholarly Works - Journal articles

IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies.

Journal article Am J Gastroenterol · January 2011 Genome-wide association studies (GWAS) have recently identified host genetic variation to be critical for predicting treatment response and spontaneous clearance in patients infected with hepatitis C virus (HCV). These important new studies are reviewed an ... Full text Link to item Cite

Genetic variation in IL28B: impact on drug development for chronic hepatitis C infection.

Journal article Clin Pharmacol Ther · November 2010 As more pharmacogenomic insights into diseases and their treatments and toxicities are published each year, the challenge arises to incorporate such insights into clinical practice and drug development. For instance, recent genomic discoveries related to h ... Full text Link to item Cite