Skip to main content

Pengfei Song

Associate Professor of Biomedical Engineering
Biomedical Engineering
1427 Fitzpatrick Center, Box 90281, Durham, NC 27708

Overview


Dr. Pengfei Song conducted his PhD and postdoctoral training on the topics of ultrasound elastography and microvascular imaging under the supervisions of Drs. James Greenleaf and Shigao Chen at Mayo Clinic. Before joining Duke University, Dr. Pengfei Song was a Y. T. Lo Faculty Fellow and Associate Professor of Electrical and Computer Engineering at the University of Illinois Urbana-Champaign. His current research interests include ultrafast ultrasound imaging, super-resolution ultrasound, functional ultrasound, 3D ultrasound imaging, deep learning applied to ultrasound imaging, and ultrasound shear wave elastography. 

Dr. Song has published over 100 peer-reviewed journal papers with a Google Scholar total citation exceeding 6200 and an h-index of 42 (March 2025). He holds several patents that have been licensed and commercialized by major ultrasound companies and used worldwide in the clinic. Dr. Song has delivered over 30 invited presentations including twice at the Gordon Research Conference. He has been consistently ranked as an excellent instructor by his students.

Dr. Song is a recipient of the NIH K99/R00 Pathway to Independence Award, the NSF CAREER Award, the NIBIB Trailblazer Award, the IEEE Ultrasonics Early Career Investigator Award, the Chan Zuckerberg Initiative (CZI) Early Career Acceleration Award, and the Campus Distinguished Promotion Award at the University of Illinois.His research program has been continuously funded by NIH, DOD CDMRP, and NSF. He is an elected Fellow of the American Institute of Ultrasound in Medicine (AIUM), a Senior Member of the National Academy of Inventors(NAI), a Senior Member of IEEE, and a Full Member of the Acoustical Society of America (ASA). 

Current Appointments & Affiliations


Associate Professor of Biomedical Engineering · 2025 - Present Biomedical Engineering, Pratt School of Engineering

Recent Publications


Combined Nanodrops Imaging and Ultrasound Localization Microscopy for Detecting Intracerebral Hemorrhage.

Journal Article Ultrasound in medicine & biology · April 2025 ObjectiveAdvanced imaging methods are crucial for understanding stroke mechanisms and discovering effective treatments to reduce bleeding and enhance recovery. In pre-clinical in vivo stroke imaging, MRI, CT and optical imaging are commonly used t ... Full text Cite

Super-Resolution Ultrasound: From Data Acquisition and Motion Correction to Localization, Tracking, and Evaluation.

Journal Article IEEE transactions on ultrasonics, ferroelectrics, and frequency control · April 2025 Super-resolution ultrasound (SRUS) imaging through localizing and tracking microbubbles (MBs), also known as ultrasound localization microscopy (ULM), has achieved unprecedented resolution in deep tissue in vivo. In this review, we will focus on the key te ... Full text Cite
View All Publications

Recent Grants


CAREER: Super-resolution Ultrasound Imaging for High-resolution Functional Mapping of the Brain

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2025 - 2028

3D real-time super-resolution cavitation mapping in laser lithotripsy of urinary stone disease

ResearchCo Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2028

Whole-brain Functional Super-Resolution Ultrasound Imaging

ResearchPrincipal Investigator · Awarded by Chan Zuckerberg Initiative · 2024 - 2027

View All Grants

Education, Training & Certifications


Mayo Clinic · 2014 Ph.D.

External Links


Song Lab website