Scholars@Duke

• Background
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  Education, Training, & Certifications

  • M.D., Columbia University 2002
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  Duke Appointment History

  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2008 - 2013
• Research
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  Selected Grants

  • Akt/GSK-3 Signaling Cascade and the Actions of Dopamine awarded by National Institutes of Health 2005 - 2020
  • Simultaneous and Bidirectional Chemogenetic Control of Mesolimbic and Nigrostriatal Circuits awarded by National Institutes of Health 2018 - 2020
  • Whole brain multimodal microscopy of an apoptosis reporter mouse awarded by National Institutes of Health 2012 - 2014
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Boone, Peter G., Lauren K. Rochelle, Joshua D. Ginzel, Veronica Lubkov, Wendy L. Roberts, P. J. Nicholls, Cheryl Bock, et al. “A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion.” Nat Commun 10, no. 1 (December 2, 2019): 5490. https://doi.org/10.1038/s41467-019-13330-y.
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    • Jacobsen, Jacob P. R., Adrianna Oh, Rachel Bangle, Wendy L. Roberts, Elizabeth L. Royer, Nathan Modesto, Sonora A. Windermere, et al. “Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.” Neuropsychopharmacology 44, no. 12 (November 2019): 2082–90. https://doi.org/10.1038/s41386-019-0400-1.
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    • Beraldo, Flavio H., Valeriy G. Ostapchenko, Jason Z. Xu, Gianni M. Di Guglielmo, Jue Fan, Peter J. Nicholls, Marc G. Caron, Vania F. Prado, and Marco A. M. Prado. “Mechanisms of neuroprotection against ischemic insult by stress-inducible phosphoprotein-1/prion protein complex.” J Neurochem 145, no. 1 (April 2018): 68–79. https://doi.org/10.1111/jnc.14281.
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    • Xie, Luke, Russell Dibb, Gary P. Cofer, Wei Li, Peter J. Nicholls, G Allan Johnson, and Chunlei Liu. “Susceptibility tensor imaging of the kidney and its microstructural underpinnings.” Magn Reson Med 73, no. 3 (March 2015): 1270–81. https://doi.org/10.1002/mrm.25219.
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    • Urs, Nikhil M., Peter J. Nicholls, and Marc G. Caron. “Integrated approaches to understanding antipsychotic drug action at GPCRs.” Curr Opin Cell Biol 27 (April 2014): 56–62. https://doi.org/10.1016/j.ceb.2013.11.002.
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    • Zhang, X., P. J. Nicholls, G. Laje, T. D. Sotnikova, R. R. Gainetdinov, P. R. Albert, G. Rajkowska, et al. “A functional alternative splicing mutation in human tryptophan hydroxylase-2.” Mol Psychiatry 16, no. 12 (December 2011): 1169–76. https://doi.org/10.1038/mp.2010.99.
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    • Salahpour, Ali, Amy J. Ramsey, Ivan O. Medvedev, Brian Kile, Tatyana D. Sotnikova, Ericka Holmstrand, Valentina Ghisi, et al. “Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter.” Proc Natl Acad Sci U S A 105, no. 11 (March 18, 2008): 4405–10. https://doi.org/10.1073/pnas.0707646105.
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    • Badea, Alexandra, Peter J. Nicholls, G Allan Johnson, and William C. Wetsel. “Neuroanatomical phenotypes in the reeler mouse.” Neuroimage 34, no. 4 (February 15, 2007): 1363–74. https://doi.org/10.1016/j.neuroimage.2006.09.053.
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    • Nicholls, Peter J., Kurian Abraham, Kathryn M. Connor, Jerilyn Ross, Jonathan R. T. Davidson, and Jonathan R. T. Anxiety Disorders Association of America. “Trauma and posttraumatic stress in users of the Anxiety Disorders Association of America Web site.” Compr Psychiatry 47, no. 1 (January 2006): 30–34. https://doi.org/10.1016/j.comppsych.2005.04.006.
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    • Njenga, Frank G., P. J. Nicholls, Caroline Nyamai, Pius Kigamwa, and Jonathan R. T. Davidson. “Post-traumatic stress after terrorist attack: psychological reactions following the US embassy bombing in Nairobi: Naturalistic study.” Br J Psychiatry 185 (October 2004): 328–33. https://doi.org/10.1192/bjp.185.4.328.
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  • Conference Papers

    • Xu, J. Z., F. H. Beraldo, V. G. Ostapchenko, J. Fan, P. J. Nicholls, M. G. Caron, V. R. Martins, V. F. Prado, and M. A. Prado. “Elucidating the Neuroprotective Mechanism Induced by Stress-Inducible Phosphoprotein-1 on Ischemic Insult.” In Stroke, 45:E263–E263. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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