Scholars@Duke
Neil Allen Petry

Neil Allen Petry

Associate Professor Emeritus of Radiology
Radiology
Box 3304 Med Ctr, Durham, NC 27710
0023, Sub-Basement, Purple Zon, Duke Clinics, 200 Trent Drive, Durham, NC 27710

Featured Works

First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer.

Journal article J Nucl Med · March 2013 Featured Publication UNLABELLED: This phase 1 study was performed to determine the pharmacokinetics and ability to visualize prostate cancer in bone, soft-tissue, and the prostate gland using (123)I-MIP-1072 and (123)I-MIP-1095, novel radiolabeled small molecules targeting pro ... Full text Link to item Cite

The future of USP monographs for PET drugs.

Journal article J Nucl Med · March 2013 Featured Publication Full text Open Access Link to item Cite

Alumina Depyrogenates F 18 Fludeoxyglucose Injection during Purification Processes.

Journal article PDA journal of pharmaceutical science and technology · May 2012 Featured Publication Endotoxin indicators (EIs) and photometric bacterial endotoxin test (BET) assays were used to determine the capacity of alumina (Al(2)O(3)) for removing endotoxin from a parenteral solution. Fludeoxyglucose F 18 (FDG) Injection, USP, a radioactive imaging ... Full text Cite

Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans.

Journal article Neurosurgery · September 2011 Featured Publication BACKGROUND: Convection-enhanced delivery (CED) permits site-specific therapeutic drug delivery within interstitial spaces at increased dosages through circumvention of the blood-brain barrier. CED is currently limited by suboptimal methodologies for monito ... Full text Link to item Cite

Operation of a radiopharmacy for a clinical trial.

Journal article Seminars in nuclear medicine · September 2010 Featured Publication Clinical investigations of radiopharmaceuticals are undertaken to advance promising compounds toward approval by the Food and Drug Administration (FDA) as "legend drugs." This FDA approval requires that the safety and efficacy of the investigational drug ( ... Full text Cite

Targeting Metastatic Prostate Cancer (PCa) Using I-123-MIP-1072 & I-123-MIP-1095: A Phase I Clinical Study in Patients

Journal article EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING · September 1, 2009 Featured Publication Link to item Cite

Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors.

Journal article Neuro Oncol · June 2008 Featured Publication The purpose of this study is to determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and intracerebral distribution of a recombinant toxin (TP-38) targeting the epidermal growth factor receptor in patients with recurrent malignant brai ... Full text Link to item Cite

PET of hypoxia and perfusion with 62Cu-ATSM and 62Cu-PTSM using a 62Zn/62Cu generator.

Journal article AJR Am J Roentgenol · February 2008 Featured Publication OBJECTIVE: Copper-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) and copper-pyruvaldehyde-bis(N4-methylthiosemicarbazone) (Cu-PTSM) are being studied as potential markers of hypoxia and perfusion, respectively. The use of short-lived radionuclides (e.g ... Full text Link to item Cite

A performance evaluation of 90Y dose-calibrator measurements in nuclear pharmacies and clinics in the United States.

Journal article Appl Radiat Isot · February 2008 Featured Publication A blind performance test was conducted to evaluate dose-calibrator measurements at nuclear pharmacies in the United States (US). Two test-sample geometries were chosen to represent those used for measurements of 90Y-ibritumomab tiuxetan (ZEVALIN). The radi ... Full text Link to item Cite

Left ventricular functional assessment in mice: feasibility of high spatial and temporal resolution ECG-gated blood pool SPECT.

Journal article Radiology · November 2007 Featured Publication PURPOSE: To prospectively determine feasibility of evaluating murine left ventricular (LV) function with electrocardiographically (ECG)-gated blood pool single photon emission computed tomography (SPECT). MATERIALS AND METHODS: All animal studies had insti ... Full text Link to item Cite

Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning.

Journal article Neurosurgery · February 2007 Featured Publication OBJECTIVE: Convection-enhanced delivery (CED) holds tremendous potential for drug delivery to the brain. However, little is known about the volume of distribution achieved within human brain tissue or how target anatomy and catheter positioning influence d ... Full text Link to item Cite

Explanations and unresolved issues pertaining to the development of the Nuclear Pharmacy Compounding Guidelines.

Journal article Journal of the American Pharmaceutical Association (Washington, D.C. : 1996) · September 2002 Featured Publication ObjectivesTo provide background information related to the development of the Nuclear Pharmacy Compounding Guidelines, to discuss regulatory complexities related to radiopharmaceutical compounding practice, and to summarize the gaps in the current ... Full text Cite

Radioimmunotherapy of B-cell lymphoma with [131I]anti-B1 (anti-CD20) antibody.

Journal article N Engl J Med · August 12, 1993 Featured Publication BACKGROUND: Many patients with non-Hodgkin's lymphomas are not cured by current therapies, and new approaches to treatment are needed. As part of an ongoing phase 1 study, we examined the effect of radioimmunotherapy with 131I-labeled B-cell-specific anti- ... Full text Link to item Cite