Scholars@Duke
Salvatore Vincent Pizzo

Salvatore Vincent Pizzo

Professor Emeritus of Pathology
Pathology
pizzo001@mc.duke.edu
Rm 3059 Duke South Hospital, Duke Box 3712, Durham, NC 27710
Rm 3059 Duke South Hospital, Durham, NC 27710

Scholarly Works - Book sections

The Endoplasmic Reticulum Chaperone GRP78 Also Functions as a Cell Surface Signaling Receptor

Book section · January 1, 2018 The Glucose Regulated Protein 78,000 (GRP78) is a member of the heat shock protein family in the endoplasmic reticulum to regulate protein quality control and degradation. We and others demonstrated that GRP78 is preferentially translocated onto the cell s ... Full text Cite

Novel Cell Surface Targets for the Plasminogen Activating System in the Brain: Implications for Human Disease

Book section · January 1, 2018 The plasminogen (Pg) activator system plays an important role in the central nervous system (CNS), including processes of neuronal migration, neurite outgrowth, and neuronal plasticity. Pg and tissue-type plasminogen activator (t-PA) are primarily involved ... Full text Cite

An Historical Perspective: Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

Book section · January 1, 2018 This chapter will present a historical perspective with respect to the presence of Glucose Regulated Protein 78,000 (GRP78) on the cell surface. Its presence there was completely unexpected since this protein normally functions as a molecular chaperone wit ... Full text Cite