Praveen Rao Juvvadi | Scholars@Duke

Praveen Rao Juvvadi
Associate Professor in Pediatrics

My research interests focus on understanding the roles for calcineurin control over hyphal growth and septation and its interactants in Aspergillus fumigatus .

Current Appointments & Affiliations

Associate Professor in Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2021

Contact Information

00565 Hosp South, Durham, NC 27710
Box 3499 Med Ctr, Durham, NC 27710
praveen.juvvadi@duke.edu (919) 681-2613

Background
Education, Training, & Certifications
- Ph.D., Osmania University (India) 1999
Duke Appointment History
- Associate Professor in Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2020
- Assistant Professor in Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2012 - 2020
Expertise
Subject Headings
Research
Selected Grants
- Diagnosis and Outcomes of Pulmonary Invasive Mold Infections in Immunocompromised Children awarded by National Institutes of Health 2018 - 2023
- Structural Biological Development of Fungal-Specific Calcineurin Inhibitors awarded by National Institutes of Health 2014 - 2021
- Discovering novel antifungal agents via multi-species profiling of a structurally and stereochemically diverse, well-validated compound library awarded by Broad Institute 2019 - 2021
- Phosphoproteomic identification of Aspergillus fumigatus virulence-associated protein kinase A downstream effectors awarded by National Institutes of Health 2018 - 2020
- Defining the Aspergillus fumigatus Calcineurin-Dependent Regulatory Network through Whole Phosphoproteome Analysis awarded by National Institutes of Health 2016 - 2019
- Structural Biological Development of Fungal-Specific Calcineurin Inhibitors awarded by National Institutes of Health 2014 - 2019
- Development of anti-Aspergillus single chain Abs as serum and imaging diagnostics awarded by National Institutes of Health 2010 - 2015
- Identification of calcineurin-binding proteins in A. fumigatus septum formation awarded by National Institutes of Health 2012 - 2014
- Calcineurin Inhibition to Halt Aspergillus fumigatus Hyphae and Virulence awarded by National Institutes of Health 2010 - 2012
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Shwab, E Keats, Praveen R. Juvvadi, Greg Waitt, Shareef Shaheen, John Allen, Erik J. Soderblom, Benjamin G. Bobay, Yohannes G. Asfaw, M Arthur Moseley, and William J. Steinbach. “The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets.” Mbio 11, no. 6 (December 15, 2020). https://doi.org/10.1128/mBio.02880-20.
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  - Roundtree, Mark T., Praveen R. Juvvadi, E Keats Shwab, D Christopher Cole, and William J. Steinbach. “Aspergillus fumigatus Cyp51A and Cyp51B Proteins Are Compensatory in Function and Localize Differentially in Response to Antifungals and Cell Wall Inhibitors.” Antimicrob Agents Chemother 64, no. 10 (September 21, 2020). https://doi.org/10.1128/AAC.00735-20.
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  - Xu-Vanpala, Shengjie, M Elizabeth Deerhake, Joshua D. Wheaton, Morgan E. Parker, Praveen R. Juvvadi, Nancie MacIver, Maria Ciofani, and Mari L. Shinohara. “Functional heterogeneity of alveolar macrophage population based on expression of CXCL2.” Sci Immunol 5, no. 50 (August 7, 2020). https://doi.org/10.1126/sciimmunol.aba7350.
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  - Renshaw, Hilary, Praveen R. Juvvadi, D Christopher Cole, and William J. Steinbach. “The class V myosin interactome of the human pathogen Aspergillus fumigatus reveals novel interactions with COPII vesicle transport proteins.” Biochem Biophys Res Commun 527, no. 1 (June 18, 2020): 232–37. https://doi.org/10.1016/j.bbrc.2020.04.111.
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  - Juvvadi, Praveen R., Benjamin G. Bobay, Sophie M. C. Gobeil, D Christopher Cole, Ronald A. Venters, Joseph Heitman, Leonard D. Spicer, and William J. Steinbach. “FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus.” Biochem Biophys Res Commun 526, no. 1 (May 21, 2020): 48–54. https://doi.org/10.1016/j.bbrc.2020.03.062.
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  - Juvvadi, Praveen R., David Fox, Benjamin G. Bobay, Michael J. Hoy, Sophie M. C. Gobeil, Ronald A. Venters, Zanetta Chang, et al. “Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.” Nat Commun 10, no. 1 (September 19, 2019): 4275. https://doi.org/10.1038/s41467-019-12199-1.
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  - Shwab, E Keats, Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, Blake C. Barrington, Yohannes G. Asfaw, M Arthur Moseley, and William J. Steinbach. “Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus.” Mol Microbiol 112, no. 1 (July 2019): 62–80. https://doi.org/10.1111/mmi.14254.
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  - Juvvadi, Praveen R., D Christopher Cole, Katie Falloon, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus.” Biochem Biophys Res Commun 505, no. 3 (November 2, 2018): 740–46. https://doi.org/10.1016/j.bbrc.2018.09.186.
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  - Renshaw, Hilary, José M. Vargas-Muñiz, Praveen R. Juvvadi, Amber D. Richards, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth.” J Cell Sci 131, no. 3 (February 7, 2018). https://doi.org/10.1242/jcs.205955.
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  - Juvvadi, Praveen R., M Arthur Moseley, Christopher J. Hughes, Erik J. Soderblom, Sarah Lennon, Simon R. Perkins, J Will Thompson, et al. “Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.” J Proteome Res 17, no. 2 (February 2, 2018): 780–93. https://doi.org/10.1021/acs.jproteome.7b00499.
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  - Moseley, M Arthur, Christopher J. Hughes, Praveen R. Juvvadi, Erik J. Soderblom, Sarah Lennon, Simon R. Perkins, J Will Thompson, et al. “Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization.” J Proteome Res 17, no. 2 (February 2, 2018): 770–79. https://doi.org/10.1021/acs.jproteome.7b00464.
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  - Shwab, Elliot K., Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, Martin A. Moseley, Nathan I. Nicely, and William J. Steinbach. “Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms.” Febs Lett 591, no. 22 (November 2017): 3730–44. https://doi.org/10.1002/1873-3468.12886.
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  - Moreno-Velásquez, Sergio D., Constanze Seidel, Praveen R. Juvvadi, William J. Steinbach, and Nick D. Read. “Caspofungin-Mediated Growth Inhibition and Paradoxical Growth in Aspergillus fumigatus Involve Fungicidal Hyphal Tip Lysis Coupled with Regenerative Intrahyphal Growth and Dynamic Changes in β-1,3-Glucan Synthase Localization.” Antimicrob Agents Chemother 61, no. 10 (October 2017). https://doi.org/10.1128/AAC.00710-17.
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  - Juvvadi, Praveen R. “Balancing iron and calcium: Flavin carrier family proteins in Aspergillus fumigatus virulence.” Virulence 8, no. 6 (August 18, 2017): 621–24. https://doi.org/10.1080/21505594.2016.1257459.
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  - Vargas-Muñiz, José M., Hilary Renshaw, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, Jonathan M. Palmer, Praveen R. Juvvadi, Nancy P. Keller, and William J. Steinbach. “Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus.” Biochem Biophys Res Commun 485, no. 2 (April 1, 2017): 221–26. https://doi.org/10.1016/j.bbrc.2017.02.116.
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  - Juvvadi, Praveen R., Soo Chan Lee, Joseph Heitman, and William J. Steinbach. “Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach.” Virulence 8, no. 2 (February 17, 2017): 186–97. https://doi.org/10.1080/21505594.2016.1201250.
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  - Shwab, E Keats, Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, Nathan I. Nicely, Yohannes G. Asfaw, and William J. Steinbach. “A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus.” Mbio 8, no. 1 (February 7, 2017). https://doi.org/10.1128/mBio.02319-16.
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  - Vargas-Muñiz, Jose M., Praveen R. Juvvadi, and William J. Steinbach. “Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures.” Microbiology (Reading) 162, no. 9 (September 2016): 1527–34. https://doi.org/10.1099/mic.0.000359.
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  - Renshaw, Hilary, José M. Vargas-Muñiz, Amber D. Richards, Yohannes G. Asfaw, Praveen R. Juvvadi, and William J. Steinbach. “Distinct Roles of Myosins in Aspergillus fumigatus Hyphal Growth and Pathogenesis.” Infect Immun 84, no. 5 (May 2016): 1556–64. https://doi.org/10.1128/IAI.01190-15.
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  - Tonthat, Nam K., Praveen Rao Juvvadi, Hengshan Zhang, Soo Chan Lee, Ron Venters, Leonard Spicer, William J. Steinbach, Joseph Heitman, and Maria A. Schumacher. “Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.” Mbio 7, no. 2 (April 26, 2016): e00492–e00416. https://doi.org/10.1128/mBio.00492-16.
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  - Juvvadi, Praveen R., Charles W. Pemble, Yan Ma, and William J. Steinbach. “Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in Aspergillus fumigatus.” Febs Lett 590, no. 4 (February 2016): 501–8. https://doi.org/10.1002/1873-3468.12075.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, and William J. Steinbach. “Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus.” Crit Rev Microbiol 42, no. 2 (2016): 310–21. https://doi.org/10.3109/1040841X.2014.947239.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, and William J. Steinbach. “Editorial: Advances in Aspergillus fumigatus Pathobiology.” Front Microbiol 7 (2016): 43. https://doi.org/10.3389/fmicb.2016.00043.
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  - Vargas-Muñiz, José M., Hilary Renshaw, Amber D. Richards, Greg Waitt, Erik J. Soderblom, Martin A. Moseley, Yohannes Asfaw, Praveen R. Juvvadi, and William J. Steinbach. “Dephosphorylation of the Core Septin, AspB, in a Protein Phosphatase 2A-Dependent Manner Impacts Its Localization and Function in the Fungal Pathogen Aspergillus fumigatus.” Front Microbiol 7 (2016): 997. https://doi.org/10.3389/fmicb.2016.00997.
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  - Juvvadi, Praveen R., and William J. Steinbach. “Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here?” Pathogens 4, no. 4 (December 16, 2015): 883–93. https://doi.org/10.3390/pathogens4040883.
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  - Steinbach, William J., Frédéric Lamoth, and Praveen R. Juvvadi. “Potential Microbiological Effects of Higher Dosing of Echinocandins.” Clin Infect Dis 61 Suppl 6 (December 1, 2015): S669–77. https://doi.org/10.1093/cid/civ725.
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  - Juvvadi, Praveen R., Alberto Muñoz, Frédéric Lamoth, Erik J. Soderblom, M Arthur Moseley, Nick D. Read, and William J. Steinbach. “Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus.” Antimicrob Agents Chemother 59, no. 8 (August 2015): 4946–55. https://doi.org/10.1128/AAC.00263-15.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus.” Antimicrob Agents Chemother 59, no. 8 (August 2015): 4727–33. https://doi.org/10.1128/AAC.00946-15.
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  - Vargas-Muñiz, José M., Hilary Renshaw, Amber D. Richards, Frédéric Lamoth, Erik J. Soderblom, M Arthur Moseley, Praveen R. Juvvadi, and William J. Steinbach. “The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence.” Fungal Genet Biol 81 (August 2015): 41–51. https://doi.org/10.1016/j.fgb.2015.05.014.
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  - Lamoth, Frédéric, Barbara D. Alexander, Praveen R. Juvvadi, and William J. Steinbach. “Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.” J Antimicrob Chemother 70, no. 5 (May 2015): 1408–11. https://doi.org/10.1093/jac/dku549.
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  - Falloon, Katie, Praveen R. Juvvadi, Amber D. Richards, José M. Vargas-Muñiz, Hilary Renshaw, and William J. Steinbach. “Characterization of the FKBP12-Encoding Genes in Aspergillus fumigatus.” Plos One 10, no. 9 (2015): e0137869. https://doi.org/10.1371/journal.pone.0137869.
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  - Juvvadi, Praveen R., Yan Ma, Amber D. Richards, Erik J. Soderblom, M Arthur Moseley, Frédéric Lamoth, and William J. Steinbach. “Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus.” Front Microbiol 6 (2015): 175. https://doi.org/10.3389/fmicb.2015.00175.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, and William J. Steinbach. “Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis.” Front Microbiol 6 (2015): 96. https://doi.org/10.3389/fmicb.2015.00096.
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  - Juvvadi, Praveen R., Frédéric Lamoth, and William J. Steinbach. “Calcineurin-mediated regulation of hyphal growth, septation, and virulence in Aspergillus fumigatus.” Mycopathologia 178, no. 5–6 (December 2014): 341–48. https://doi.org/10.1007/s11046-014-9794-9.
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  - Lamoth, F., P. R. Juvvadi, and W. J. Steinbach. “Heat Shock Protein 90 (Hsp90) in Fungal Growth and Pathogenesis.” Current Fungal Infection Reports 8, no. 4 (December 1, 2014): 296–301. https://doi.org/10.1007/s12281-014-0195-9.
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  - Sugui, Janyce A., Kyung J. Kwon-Chung, Praveen R. Juvvadi, Jean-Paul Latgé, and William J. Steinbach. “Aspergillus fumigatus and related species.” Cold Spring Harb Perspect Med 5, no. 2 (November 6, 2014): a019786. https://doi.org/10.1101/cshperspect.a019786.
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  - Juvvadi, Praveen R., Frédéric Lamoth, and William J. Steinbach. “Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis.” Fungal Biol Rev 28, no. 2–3 (October 2014): 56–69. https://doi.org/10.1016/j.fbr.2014.02.004.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, Christopher Gehrke, Yohannes G. Asfaw, and William J. Steinbach. “Transcriptional activation of heat shock protein 90 mediated via a proximal promoter region as trigger of caspofungin resistance in Aspergillus fumigatus.” J Infect Dis 209, no. 3 (February 1, 2014): 473–81. https://doi.org/10.1093/infdis/jit530.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, Erik J. Soderblom, M Arthur Moseley, Yohannes G. Asfaw, and William J. Steinbach. “Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus.” Antimicrob Agents Chemother 58, no. 4 (2014): 1889–96. https://doi.org/10.1128/AAC.02286-13.
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  - Juvvadi, Praveen Rao, Detti Belina, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus.” Biochem Biophys Res Commun 431, no. 3 (February 15, 2013): 547–53. https://doi.org/10.1016/j.bbrc.2013.01.020.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, Christopher Gehrke, and William J. Steinbach. “In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains.” Antimicrob Agents Chemother 57, no. 2 (February 2013): 1035–39. https://doi.org/10.1128/AAC.01857-12.
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  - Juvvadi, Praveen R., Christopher Gehrke, Jarrod R. Fortwendel, Frédéric Lamoth, Erik J. Soderblom, Erik C. Cook, Michael A. Hast, et al. “Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus.” Plos Pathog 9, no. 8 (2013): e1003564. https://doi.org/10.1371/journal.ppat.1003564.
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  - Lamoth, Frédéric, Praveen R. Juvvadi, Jarrod R. Fortwendel, and William J. Steinbach. “Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus.” Eukaryot Cell 11, no. 11 (November 2012): 1324–32. https://doi.org/10.1128/EC.00032-12.
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  - Fortwendel, Jarrod R., Praveen R. Juvvadi, Luise E. Rogg, Yohannes G. Asfaw, Kimberlie A. Burns, Scott H. Randell, and William J. Steinbach. “Plasma membrane localization is required for RasA-mediated polarized morphogenesis and virulence of Aspergillus fumigatus.” Eukaryot Cell 11, no. 8 (August 2012): 966–77. https://doi.org/10.1128/EC.00091-12.
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  - Rogg, Luise E., Jarrod R. Fortwendel, Praveen R. Juvvadi, and William J. Steinbach. “Regulation of expression, activity and localization of fungal chitin synthases.” Med Mycol 50, no. 1 (January 2012): 2–17. https://doi.org/10.3109/13693786.2011.577104.
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  - Juvvadi, Praveen Rao, Jarrod R. Fortwendel, Luise E. Rogg, Kimberlie A. Burns, Scott H. Randell, and William J. Steinbach. “Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus.” Mol Microbiol 82, no. 5 (December 2011): 1235–59. https://doi.org/10.1111/j.1365-2958.2011.07886.x.
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  - Rogg, Luise E., Jarrod R. Fortwendel, Praveen Rao Juvvadi, Amanda Lilley, and William J. Steinbach. “The chitin synthase genes chsA and chsC are not required for cell wall stress responses in the human pathogen Aspergillus fumigatus.” Biochem Biophys Res Commun 411, no. 3 (August 5, 2011): 549–54. https://doi.org/10.1016/j.bbrc.2011.06.180.
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  - Fortwendel, Jarrod R., Praveen R. Juvvadi, Luise E. Rogg, and William J. Steinbach. “Regulatable Ras activity is critical for proper establishment and maintenance of polarity in Aspergillus fumigatus.” Eukaryot Cell 10, no. 4 (April 2011): 611–15. https://doi.org/10.1128/EC.00315-10.
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  - Steinbach, William J., Praveen R. Juvvadi, Jarrod R. Fortwendel, and Luise E. Rogg. “Newer combination antifungal therapies for invasive aspergillosis.” Med Mycol 49 Suppl 1 (April 2011): S77–81. https://doi.org/10.3109/13693786.2010.499374.
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  - Juvvadi, Praveen Rao, Jarrod R. Fortwendel, Luise E. Rogg, and William J. Steinbach. “Differential localization patterns of septins during growth of the human fungal pathogen Aspergillus fumigatus reveal novel functions.” Biochem Biophys Res Commun 405, no. 2 (February 11, 2011): 238–43. https://doi.org/10.1016/j.bbrc.2011.01.017.
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  - Seshime, Yasuyo, Praveen Rao Juvvadi, Katsuhiko Kitamoto, Yutaka Ebizuka, Takamasa Nonaka, and Isao Fujii. “Aspergillus oryzae type III polyketide synthase CsyA is involved in the biosynthesis of 3,5-dihydroxybenzoic acid.” Bioorg Med Chem Lett 20, no. 16 (August 15, 2010): 4785–88. https://doi.org/10.1016/j.bmcl.2010.06.119.
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  - Seshime, Yasuyo, Praveen Rao Juvvadi, Katsuhiko Kitamoto, Yutaka Ebizuka, and Isao Fujii. “Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB.” Bioorg Med Chem 18, no. 12 (June 15, 2010): 4542–46. https://doi.org/10.1016/j.bmc.2010.04.058.
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  - Fortwendel, Jarrod R., Praveen R. Juvvadi, B Zachary Perfect, Luise E. Rogg, John R. Perfect, and William J. Steinbach. “Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin.” Antimicrob Agents Chemother 54, no. 4 (April 2010): 1555–63. https://doi.org/10.1128/AAC.00854-09.
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  - Pinchai, Nadthanan, Praveen Rao Juvvadi, Jarrod R. Fortwendel, B Zachary Perfect, Luise E. Rogg, Yohannes G. Asfaw, and William J. Steinbach. “The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis.” Eukaryot Cell 9, no. 3 (March 2010): 472–76. https://doi.org/10.1128/EC.00378-09.
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  - Seshime, Yasuyo, Praveen Rao Juvvadi, Masafumi Tokuoka, Yasuji Koyama, Katsuhiko Kitamoto, Yutaka Ebizuka, and Isao Fujii. “Functional expression of the Aspergillus flavus PKS-NRPS hybrid CpaA involved in the biosynthesis of cyclopiazonic acid.” Bioorg Med Chem Lett 19, no. 12 (June 15, 2009): 3288–92. https://doi.org/10.1016/j.bmcl.2009.04.073.
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  - Pinchai, Nadthanan, B Zachary Perfect, Praveen Rao Juvvadi, Jarrod R. Fortwendel, Robert A. Cramer, Yohannes G. Asfaw, Joseph Heitman, John R. Perfect, and William J. Steinbach. “Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis.” Eukaryot Cell 8, no. 4 (April 2009): 511–19. https://doi.org/10.1128/EC.00336-08.
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  - Escaño, Cristopher Salazar, Praveen Rao Juvvadi, Feng Jie Jin, Tadashi Takahashi, Yasuji Koyama, Shuichi Yamashita, Jun-ichi Maruyama, and Katsuhiko Kitamoto. “Disruption of the Aopex11-1 gene involved in peroxisome proliferation leads to impaired Woronin body formation in Aspergillus oryzae.” Eukaryot Cell 8, no. 3 (March 2009): 296–305. https://doi.org/10.1128/EC.00197-08.
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  - Fortwendel, Jarrod R., Praveen Rao Juvvadi, Nadthanan Pinchai, B Zachary Perfect, J Andrew Alspaugh, John R. Perfect, and William J. Steinbach. “Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus.” Antimicrob Agents Chemother 53, no. 2 (February 2009): 476–82. https://doi.org/10.1128/AAC.01154-08.
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  - Juvvadi, Praveen Rao, Jarrod R. Fortwendel, Nadthanan Pinchai, B Zachary Perfect, Joseph Heitman, and William J. Steinbach. “Calcineurin localizes to the hyphal septum in Aspergillus fumigatus: implications for septum formation and conidiophore development.” Eukaryot Cell 7, no. 9 (September 2008): 1606–10. https://doi.org/10.1128/EC.00200-08.
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  - Jin, Feng Jie, Taisuke Watanabe, Praveen Rao Juvvadi, Jun-ichi Maruyama, Manabu Arioka, and Katsuhiko Kitamoto. “Double disruption of the proteinase genes, tppA and pepE, increases the production level of human lysozyme by Aspergillus oryzae.” Appl Microbiol Biotechnol 76, no. 5 (October 2007): 1059–68. https://doi.org/10.1007/s00253-007-1088-4.
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  - Juvvadi, Praveen Rao, Jun-ichi Maruyama, and Katsuhiko Kitamoto. “Phosphorylation of the Aspergillus oryzae Woronin body protein, AoHex1, by protein kinase C: evidence for its role in the multimerization and proper localization of the Woronin body protein.” Biochem J 405, no. 3 (August 1, 2007): 533–40. https://doi.org/10.1042/BJ20061678.
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  - Akao, Takeshi, Motoaki Sano, Osamu Yamada, Terumi Akeno, Kaoru Fujii, Kuniyasu Goto, Sumiko Ohashi-Kunihiro, et al. “Analysis of expressed sequence tags from the fungus Aspergillus oryzae cultured under different conditions.” Dna Res 14, no. 2 (April 2007): 47–57. https://doi.org/10.1093/dnares/dsm008.
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  - Kobayashi, Tetsuo, Keietsu Abe, Kiyoshi Asai, Katsuya Gomi, Praveen Rao Juvvadi, Masashi Kato, Katsuhiko Kitamoto, Michio Takeuchi, and Masayuki Machida. “Genomics of Aspergillus oryzae.” Biosci Biotechnol Biochem 71, no. 3 (March 2007): 646–70. https://doi.org/10.1271/bbb.60550.
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  - Juvvadi, Praveen Rao, and Subramanyam Chivukula. “Putative calmodulin-binding domains in aflatoxin biosynthesis-regulatory proteins.” Curr Microbiol 52, no. 6 (June 2006): 493–96. https://doi.org/10.1007/s00284-005-0389-z.
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  - Machida, Masayuki, Kiyoshi Asai, Motoaki Sano, Toshihiro Tanaka, Toshitaka Kumagai, Goro Terai, Ken-Ichi Kusumoto, et al. “Genome sequencing and analysis of Aspergillus oryzae.” Nature 438, no. 7071 (December 22, 2005): 1157–61. https://doi.org/10.1038/nature04300.
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  - Ishi, Kazutomo, Taisuke Watanabe, Praveen Rao Juvvadi, Jun-Ichi Maruyama, and Katsuhiko Kitamoto. “Development of a modified positive selection medium that allows to isolate Aspergillus oryzae strains cured of the integrated niaD-based plasmid.” Biosci Biotechnol Biochem 69, no. 12 (December 2005): 2463–65. https://doi.org/10.1271/bbb.69.2463.
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  - Juvvadi, Praveen Rao, Yasuyo Seshime, and Katsuhiko Kitamoto. “Genomics reveals traces of fungal phenylpropanoid-flavonoid metabolic pathway in the f ilamentous fungus Aspergillus oryzae.” J Microbiol 43, no. 6 (December 2005): 475–86.
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  - Seshime, Yasuyo, Praveen Rao Juvvadi, Isao Fujii, and Katsuhiko Kitamoto. “Genomic evidences for the existence of a phenylpropanoid metabolic pathway in Aspergillus oryzae.” Biochem Biophys Res Commun 337, no. 3 (November 25, 2005): 747–51. https://doi.org/10.1016/j.bbrc.2005.08.233.
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  - Maruyama, Jun-ichi, Praveen Rao Juvvadi, Kazutomo Ishi, and Katsuhiko Kitamoto. “Three-dimensional image analysis of plugging at the septal pore by Woronin body during hypotonic shock inducing hyphal tip bursting in the filamentous fungus Aspergillus oryzae.” Biochem Biophys Res Commun 331, no. 4 (June 17, 2005): 1081–88. https://doi.org/10.1016/j.bbrc.2005.03.233.
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  - Unno, Kenji, Praveen Rao Juvvadi, Harushi Nakajima, Katsuhiko Shirahige, and Katsuhiko Kitamoto. “Identification and characterization of rns4/vps32 mutation in the RNase T1 expression-sensitive strain of Saccharomyces cerevisiae: Evidence for altered ambient response resulting in transportation of the secretory protein to vacuoles.” Fems Yeast Res 5, no. 9 (June 2005): 801–12. https://doi.org/10.1016/j.femsyr.2005.03.003.
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  - Seshime, Yasuyo, Praveen Rao Juvvadi, Isao Fujii, and Katsuhiko Kitamoto. “Discovery of a novel superfamily of type III polyketide synthases in Aspergillus oryzae.” Biochem Biophys Res Commun 331, no. 1 (May 27, 2005): 253–60. https://doi.org/10.1016/j.bbrc.2005.03.160.
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  - Ishi, Kazutomo, Jun-ichi Maruyama, Praveen Rao Juvvadi, Harushi Nakajima, and Katsuhiko Kitamoto. “Visualizing nuclear migration during conidiophore development in Aspergillus nidulans and Aspergillus oryzae: multinucleation of conidia occurs through direct migration of plural nuclei from phialides and confers greater viability and early germination in Aspergillus oryzae.” Biosci Biotechnol Biochem 69, no. 4 (April 2005): 747–54. https://doi.org/10.1271/bbb.69.747.
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  - Jin, Feng Jie, Jun-Ichi Maruyama, Praveen Rao Juvvadi, Manabu Arioka, and Katsuhiko Kitamoto. “Development of a novel quadruple auxotrophic host transformation system by argB gene disruption using adeA gene and exploiting adenine auxotrophy in Aspergillus oryzae.” Fems Microbiol Lett 239, no. 1 (October 1, 2004): 79–85. https://doi.org/10.1016/j.femsle.2004.08.025.
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  - Jin, Feng Jie, Jun-ichi Maruyama, Praveen Rao Juvvadi, Manabu Arioka, and Katsuhiko Kitamoto. “Adenine auxotrophic mutants of Aspergillus oryzae: development of a novel transformation system with triple auxotrophic hosts.” Biosci Biotechnol Biochem 68, no. 3 (March 2004): 656–62. https://doi.org/10.1271/bbb.68.656.
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  - Juvvadi, Praveen Rao, Yutaka Kuroki, Manabu Arioka, Harushi Nakajima, and Katsuhiko Kitamoto. “Functional analysis of the calcineurin-encoding gene cnaA from Aspergillus oryzae: evidence for its putative role in stress adaptation.” Arch Microbiol 179, no. 6 (June 2003): 416–22. https://doi.org/10.1007/s00203-003-0546-3.
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  - Kuroki, Yutaka, Praveen Rao Juvvadi, Manabu Arioka, Harushi Nakajima, and Katsuhiko Kitamoto. “Cloning and characterization of vmaA, the gene encoding a 69-kDa catalytic subunit of the vacuolar H+-ATPase during alkaline pH mediated growth of Aspergillus oryzae.” Fems Microbiol Lett 209, no. 2 (April 9, 2002): 277–82. https://doi.org/10.1111/j.1574-6968.2002.tb11144.x.
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  - Juvvadi, P. R., M. Arioka, H. Nakajima, and K. Kitamoto. “Cloning and sequence analysis of cnaA gene encoding the catalytic subunit of calcineurin from Aspergillus oryzae.” Fems Microbiol Lett 204, no. 1 (October 16, 2001): 169–74. https://doi.org/10.1111/j.1574-6968.2001.tb10881.x.
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  - Rao, J. P., and C. Subramanyam. “Calmodulin mediated activation of acetyl-CoA carboxylase during aflatoxin production by Aspergillus parasiticus.” Lett Appl Microbiol 30, no. 4 (April 2000): 277–81. https://doi.org/10.1046/j.1472-765x.2000.00717.x.
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  - Jayashree, T., J. P. Rao, and C. Subramanyam. “Regulation of aflatoxin production by Ca²⁺/calmodulin-dependent protein phosphorylation and dephosphorylation.” Fems Microbiology Letters 183, no. 2 (2000): 215–19. https://doi.org/10.1016/S0378-1097(99)00642-4.
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  - Praveen Rao, J., and C. Subramanyam. “Requirement of Ca2+ for aflatoxin production: inhibitory effect of Ca2+ channel blockers on aflatoxin production by Aspergillus parasiticus NRRL 2999.” Lett Appl Microbiol 28, no. 1 (January 1999): 85–88. https://doi.org/10.1046/j.1365-2672.1999.00460.x.
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  - Praveen Rao, J., R. B. Sashidhar, and C. Subramanyam. “Inhibition of aflatoxin production by trifluoperazine in Aspergillus parasiticus NRRL 2999.” World Journal of Microbiology and Biotechnology 14, no. 1 (January 1, 1998): 71–75. https://doi.org/10.1023/A:1008876517450.
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  - Rao, J. P., G. Reena, and C. Subramanyam. “Calmodulin-dependent protein phosphorylation during conidial germination and growth of Neurospora crassa.” Mycological Research 101, no. 12 (January 1, 1997): 1484–88. https://doi.org/10.1017/S0953756297004255.
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