Scholars@Duke
Quinn Ostrom

Quinn Ostrom

Associate Professor in Neurosurgery
Neurosurgery, Neuro-Oncology
571 Research Drive, MSRB-1, Rm 442, Durham, NC 27710

Scholarly Works - Other

Supplementary Table S4 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Table S4. Multivariate MR estimates of direct causal effects of traits on lung cancer individually conditioned on genetically influenced smoking, alcohol use, socioeconomic status, and educational attainment.</p> Full text Cite

Supplemental Table 4 from Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol

Other · November 26, 2025 <p>Supplemental Table 4. Calcitriol-24,25-dihydroxyvitamin D3-calcifediol proportion ratio (C24CPR) and calcitriol (1,25(OH)2D3) adjusted least squares mean by demographic and environmental factors.</p> ... Full text Cite

Supplemental Table 2 from Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol

Other · November 26, 2025 <p>Supplemental Table 2. Allele Frequencies and Hardy-Weinberg Equilibrium (HWE) among African American (AA) and European American (EA) Participants (Central Pennsylvania) compared with 1000 Genomes African (AFR) and European (EUR) Population ... Full text Cite

Supplementary Table S5 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Table S5. Multivariate MR estimates of direct causal effects of traits on lung cancer dually conditioned on genetically influenced smoking and educational attainment</p> ... Full text Cite

Supplementary Table S1 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Table S1. Overview of Transdisciplinary Research of Cancer in Lung of the International Lung Cancer Consortium (TRICL-ILCCO) and the OncoArray Consortium GWAS studies</p> ... Full text Cite

Supplementary Table 1 from Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol

Other · November 26, 2025 <p>Supplemental Table 1. Distribution of Vitamin D Biomarkers By Race/Ethnicity, Sex and Oral Contraceptive Use.</p> ... Full text Cite

Supplemental Table 3 from Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol

Other · November 26, 2025 <p>Supplemental Table 3. Pairwise D’ and r2 Linkage Disequilibrium Values between Single Nucleotide Polymorphisms and Spearman's Correlation with West African Genetic Ancestry Proportion, African American (N=188) matched with European America ... Full text Cite

Supplementary Table S2 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Table S2. Complete list of SNPs used as genetic instrumental variables (IVs) for causal effect modeling of traits with lung cancer outcomes.</p> ... Full text Cite

Supplementary Figure S2 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Figure S2. IVW multivariate MR estimation of direct impact of traits on lung squamous cell carcinoma development, conditioned on smoking (pack years per lifespan), income, and education.</p> ... Full text Cite

Supplementary Figure S3 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Figure S3. IVW multivariate MR estimation of direct impact of traits on small cell lung cancer development, conditioned on smoking (pack years per lifespan), income, and education.</p> ... Full text Cite

Supplementary Table S3 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Table S3. Univariate MR estimations of total causal effects between traits with lung cancer risks.</p> ... Full text Cite

Supplementary Figure S1 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · November 26, 2025 <p>Supplementary Figure S1. IVW multivariate MR estimation of direct impact of traits on lung adenocarcinoma development, conditioned on smoking (pack years per lifespan), income, and years of schooling.</p> ... Full text Cite

Supplementary Figure 1 from Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol

Other · November 26, 2025 <p>Supplemental Figures 1a through 1d. Log linear plots of Plasma Calcitriol (1,25(OH)2D3) and plasma Calcitriol-24,25-Dihydroxyvitamin D3-Calcifediol Proportion ratio (C24CPR) in Relation to the Skin Melanin Index (SMI) and West African Gene ... Full text Cite

Table S6 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S6 provides results by timing of brain metastasis (at diagnosis or after diagnosis)</p> ... Full text Cite

Table S2 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S2 shows codes used to classify therapies</p> ... Full text Cite

Figure S4 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Figure S4 shows sex-specific hazard of death based on atopic trait</p> ... Full text Cite

Table S3 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S3 provides an overview of characteristics of included individuals by atopic disease status</p> ... Full text Cite

Figure S2 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Figure S2 shows the correlation between atopic conditions and other prognostic variables</p> ... Full text Cite

Figure S5 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Figure S5 shows probability of brain metastasis free survival by atopic trait</p> ... Full text Cite

Table S7 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S7 provides results for those without metastatic disease at diagnosis</p> ... Full text Cite

Table S5 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S5 provides adjusted results from survival and cumulative incidence analyses</p> ... Full text Cite

Data from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <div>AbstractBackground:<p>Development of new melanoma therapies has increased survival, and more patients are living to develop brain metastasis (BrM). Identifying those at increased risk of BrM is of significant public health importan ... Full text Cite

Table S1 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S1 shows codes used to classify atopic disease types</p> ... Full text Cite

Figure S3 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Figure S3 shows association between atopic traits and treatment choice</p> ... Full text Cite

Table S4 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Table S4 provides results from univariate survival and cumulative incidence analyses</p> ... Full text Cite

Figure S1 from Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma

Other · September 2, 2025 <p>Figure S1 illustrates the data filtering process used to build the analytic dataset</p> ... Full text Cite

Supplementary Figure S1 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Figure S1. IVW multivariate MR estimation of direct impact of traits on lung adenocarcinoma development, conditioned on smoking (pack years per lifespan), income, and years of schooling.</p> ... Full text Cite

Supplementary Figure S2 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Figure S2. IVW multivariate MR estimation of direct impact of traits on lung squamous cell carcinoma development, conditioned on smoking (pack years per lifespan), income, and education.</p> ... Full text Cite

Data from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <div>Abstract<p>Introduction: Lung cancer is a complex polygenic disorder. Analysis with Mendelian randomization (MR) allows for genetically predicted risks to be estimated between exposures and outcomes. Methods: We analyzed 345 heri ... Full text Cite

Supplementary Figure S1 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Figure S1. IVW multivariate MR estimation of direct impact of traits on lung adenocarcinoma development, conditioned on smoking (pack years per lifespan), income, and years of schooling.</p> ... Full text Cite

Supplementary Table S4 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S4. Multivariate MR estimates of direct causal effects of traits on lung cancer individually conditioned on genetically influenced smoking, alcohol use, socioeconomic status, and educational attainment.</p> Full text Cite

Supplementary Figure S3 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Figure S3. IVW multivariate MR estimation of direct impact of traits on small cell lung cancer development, conditioned on smoking (pack years per lifespan), income, and education.</p> ... Full text Cite

Supplementary Table S5 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S5. Multivariate MR estimates of direct causal effects of traits on lung cancer dually conditioned on genetically influenced smoking and educational attainment</p> ... Full text Cite

Supplementary Figure S2 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Figure S2. IVW multivariate MR estimation of direct impact of traits on lung squamous cell carcinoma development, conditioned on smoking (pack years per lifespan), income, and education.</p> ... Full text Cite

Supplementary Table S1 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S1. Overview of Transdisciplinary Research of Cancer in Lung of the International Lung Cancer Consortium (TRICL-ILCCO) and the OncoArray Consortium GWAS studies</p> ... Full text Cite

Supplementary Table S3 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S3. Univariate MR estimations of total causal effects between traits with lung cancer risks.</p> ... Full text Cite

Supplementary Table S2 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S2. Complete list of SNPs used as genetic instrumental variables (IVs) for causal effect modeling of traits with lung cancer outcomes.</p> ... Full text Cite

Supplementary Table S5 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S5. Multivariate MR estimates of direct causal effects of traits on lung cancer dually conditioned on genetically influenced smoking and educational attainment</p> ... Full text Cite

Supplementary Table S1 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S1. Overview of Transdisciplinary Research of Cancer in Lung of the International Lung Cancer Consortium (TRICL-ILCCO) and the OncoArray Consortium GWAS studies</p> ... Full text Cite

Supplementary Table S3 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S3. Univariate MR estimations of total causal effects between traits with lung cancer risks.</p> ... Full text Cite

Supplementary Figure S3 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Figure S3. IVW multivariate MR estimation of direct impact of traits on small cell lung cancer development, conditioned on smoking (pack years per lifespan), income, and education.</p> ... Full text Cite

Supplementary Table S2 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S2. Complete list of SNPs used as genetic instrumental variables (IVs) for causal effect modeling of traits with lung cancer outcomes.</p> ... Full text Cite

Supplementary Table S4 from Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study

Other · September 16, 2024 <p>Supplementary Table S4. Multivariate MR estimates of direct causal effects of traits on lung cancer individually conditioned on genetically influenced smoking, alcohol use, socioeconomic status, and educational attainment.</p> Full text Cite

Data from Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma

Other · March 31, 2023 <div>Abstract<p>Genome-wide association studies (GWAS) have so far identified 25 loci associated with glioma risk, with most showing specificity for either glioblastoma (GBM) or non-GBM tumors. The majority of these GWAS susceptibility ... Full text Cite