Raul Radikovich Gainetdinov
Adjunct Associate Professor in the Department of Cell Biology
Monoaminergic and glutamatergic transmission in experimental animal models of brain pathology (Addiction, ADHD, Parkinson's Disorder and Schizophrenia).
Mechanisms of action of psychotropic drugs (antipsychotics, antidepressants and psychostimulants).
Mechanisms of action of psychotropic drugs (antipsychotics, antidepressants and psychostimulants).
Current Appointments & Affiliations
- Adjunct Associate Professor in the Department of Cell Biology, Cell Biology, Basic Science Departments 2008
Contact Information
- 477 Clin Res Labs, Durham, NC 27710
- Duke Box 3287, Durham, NC 27710
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r.gainetdinov@cellbio.duke.edu
(919) 357-2412
- Background
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Education, Training, & Certifications
- Ph.D., Russian Academy of Medical Science 1992
- M.D., Moscow Medical Academy 1988
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Duke Appointment History
- Associate Research Professor in Cell Biology, Cell Biology, Basic Science Departments 2006 - 2008
- Assistant Research Professor in Cell Biology, Cell Biology, Basic Science Departments 2000 - 2006
- Research
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Selected Grants
- Chemical Biology Approaches to Combat Parkinson's Disease and Dyskinesia awarded by National Institutes of Health 2013 - 2016
- Dopamine Receptor Regulation by GRKs in Drug Abuse awarded by National Institutes of Health 2004 - 2009
- Elucidating the actions of acetylcholine in the brain awarded by National Institutes of Health 2005 - 2008
- Genetic Analysis of Dopaminergic Reward Mechanisms awarded by National Institutes of Health 2000 - 2006
- Molecular fingerprinting of GPCR ligands in Cancer awarded by National Institutes of Health 2004 - 2006
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Gainetdinov, Raul R. “Dopamine transporter mutant mice in experimental neuropharmacology..” Naunyn Schmiedebergs Arch Pharmacol 377, no. 4–6 (June 2008): 301–13. https://doi.org/10.1007/s00210-007-0216-0.Full Text Link to Item
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Gainetdinov, Raul R. “Mesolimbic dopamine in obesity and diabetes..” Am J Physiol Regul Integr Comp Physiol 293, no. 2 (August 2007): R601–2. https://doi.org/10.1152/ajpregu.00450.2007.Full Text Link to Item
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Powell, Susan B., Virginia D. Lehmann-Masten, Martin P. Paulus, Raul R. Gainetdinov, Marc G. Caron, and Mark A. Geyer. “MDMA "ecstasy" alters hyperactive and perseverative behaviors in dopamine transporter knockout mice..” Psychopharmacology (Berl) 173, no. 3–4 (May 2004): 310–17. https://doi.org/10.1007/s00213-003-1765-7.Full Text Link to Item
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Beaulieu, Jean-Martin, Tatyana D. Sotnikova, Wei-Dong Yao, Lisa Kockeritz, James R. Woodgett, Raul R. Gainetdinov, and Marc G. Caron. “Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade..” Proc Natl Acad Sci U S A 101, no. 14 (April 6, 2004): 5099–5104. https://doi.org/10.1073/pnas.0307921101.Full Text Link to Item
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Yao, Wei-Dong, Raul R. Gainetdinov, Margaret I. Arbuckle, Tatyana D. Sotnikova, Michel Cyr, Jean-Martin Beaulieu, Gonzalo E. Torres, Seth G. N. Grant, and Marc G. Caron. “Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity..” Neuron 41, no. 4 (February 19, 2004): 625–38. https://doi.org/10.1016/s0896-6273(04)00048-0.Full Text Link to Item
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Barr, Alasdair M., Virginia Lehmann-Masten, Martin Paulus, Raul R. Gainetdinov, Marc G. Caron, and Mark A. Geyer. “The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice..” Neuropsychopharmacology 29, no. 2 (February 2004): 221–28. https://doi.org/10.1038/sj.npp.1300343.Full Text Link to Item
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Walker, J. K. L., R. R. Gainetdinov, D. S. Feldman, P. K. McFawn, M. G. Caron, R. J. Lefkowitz, R. T. Premont, and J. T. Fisher. “G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation..” Am J Physiol Lung Cell Mol Physiol 286, no. 2 (February 2004): L312–19. https://doi.org/10.1152/ajplung.00255.2003.Full Text Link to Item
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Bohn, Laura M., Raul R. Gainetdinov, and Marc G. Caron. “G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice..” Neuromolecular Med 5, no. 1 (2004): 41–50. https://doi.org/10.1385/NMM:5:1:041.Full Text Link to Item
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Gainetdinov, Raul R., Richard T. Premont, Laura M. Bohn, Robert J. Lefkowitz, and Marc G. Caron. “Desensitization of G protein-coupled receptors and neuronal functions..” Annu Rev Neurosci 27 (2004): 107–44. https://doi.org/10.1146/annurev.neuro.27.070203.144206.Full Text Link to Item
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Bohn, Laura M., Raul R. Gainetdinov, Tatyana D. Sotnikova, Ivan O. Medvedev, Robert J. Lefkowitz, Linda A. Dykstra, and Marc G. Caron. “Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice..” J Neurosci 23, no. 32 (November 12, 2003): 10265–73.Open Access Copy Link to Item
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Cyr, Michel, Jean-Martin Beaulieu, Aki Laakso, Tatyana D. Sotnikova, Wei-Dong Yao, Laura M. Bohn, Raul R. Gainetdinov, and Marc G. Caron. “Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons..” Proc Natl Acad Sci U S A 100, no. 19 (September 16, 2003): 11035–40. https://doi.org/10.1073/pnas.1831768100.Full Text Link to Item
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Miyakawa, Tsuyoshi, Lorene M. Leiter, David J. Gerber, Raul R. Gainetdinov, Tatyana D. Sotnikova, Hongkui Zeng, Marc G. Caron, and Susumu Tonegawa. “Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia..” Proc Natl Acad Sci U S A 100, no. 15 (July 22, 2003): 8987–92. https://doi.org/10.1073/pnas.1432926100.Full Text Link to Item
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Gainetdinov, Raul R., Laura M. Bohn, Tatyana D. Sotnikova, Michel Cyr, Aki Laakso, Alexander D. Macrae, Gonzalo E. Torres, et al. “Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice..” Neuron 38, no. 2 (April 24, 2003): 291–303. https://doi.org/10.1016/s0896-6273(03)00192-2.Full Text Link to Item
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Phillips, Paul E. M., Josephine M. Johns, Deborah A. Lubin, Evgeny A. Budygin, Raul R. Gainetdinov, Jeffery A. Lieberman, and R Mark Wightman. “Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine..” Brain Res 961, no. 1 (January 24, 2003): 63–72. https://doi.org/10.1016/s0006-8993(02)03840-4.Full Text Link to Item
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Gainetdinov, Raul R., and Marc G. Caron. “Monoamine transporters: from genes to behavior..” Annu Rev Pharmacol Toxicol 43 (2003): 261–84. https://doi.org/10.1146/annurev.pharmtox.43.050802.112309.Full Text Link to Item
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Torres, Gonzalo E., Raul R. Gainetdinov, and Marc G. Caron. “Plasma membrane monoamine transporters: structure, regulation and function..” Nat Rev Neurosci 4, no. 1 (January 2003): 13–25. https://doi.org/10.1038/nrn1008.Full Text Link to Item
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Laakso, Aki, Amy R. Mohn, Raul R. Gainetdinov, and Marc G. Caron. “Experimental genetic approaches to addiction..” Neuron 36, no. 2 (October 10, 2002): 213–28. https://doi.org/10.1016/s0896-6273(02)00972-8.Full Text Link to Item
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Gainetdinov, Raul R., Tatyana D. Sotnikova, and Marc G. Caron. “Monoamine transporter pharmacology and mutant mice..” Trends Pharmacol Sci 23, no. 8 (August 2002): 367–73. https://doi.org/10.1016/s0165-6147(02)02044-8.Full Text Link to Item
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Richfield, Eric K., Mona J. Thiruchelvam, Deborah A. Cory-Slechta, Charles Wuertzer, Raul R. Gainetdinov, Marc G. Caron, Donato A. Di Monte, and Howard J. Federoff. “Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice..” Exp Neurol 175, no. 1 (May 2002): 35–48. https://doi.org/10.1006/exnr.2002.7882.Full Text Link to Item
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Raevskii, K. S., R. R. Gainetdinov, E. A. Budygin, P. Mannisto, and M. Wightman. “Dopaminergic transmission in the rat striatum in vivo in conditions of pharmacological modulation..” Neurosci Behav Physiol 32, no. 2 (March 2002): 183–88. https://doi.org/10.1023/a:1013931609942.Full Text Link to Item
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Joseph, J. D., Y. -. M. Wang, P. R. Miles, E. A. Budygin, R. Picetti, R. R. Gainetdinov, M. G. Caron, and R. M. Wightman. “Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors..” Neuroscience 112, no. 1 (2002): 39–49. https://doi.org/10.1016/s0306-4522(02)00067-2.Full Text Link to Item
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Gerber, D. J., T. D. Sotnikova, R. R. Gainetdinov, S. Y. Huang, M. G. Caron, and S. Tonegawa. “Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice..” Proc Natl Acad Sci U S A 98, no. 26 (December 18, 2001): 15312–17. https://doi.org/10.1073/pnas.261583798.Full Text Link to Item
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Gainetdinov, R. R., A. R. Mohn, L. M. Bohn, and M. G. Caron. “Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter..” Proc Natl Acad Sci U S A 98, no. 20 (September 25, 2001): 11047–54. https://doi.org/10.1073/pnas.191353298.Full Text Link to Item
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Gainetdinov, R. R., A. R. Mohn, and M. G. Caron. “Genetic animal models: focus on schizophrenia..” Trends Neurosci 24, no. 9 (September 2001): 527–33. https://doi.org/10.1016/s0166-2236(00)01886-5.Full Text Link to Item
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Premont, R. T., R. R. Gainetdinov, and M. G. Caron. “Following the trace of elusive amines..” Proc Natl Acad Sci U S A 98, no. 17 (August 14, 2001): 9474–75. https://doi.org/10.1073/pnas.181356198.Full Text Link to Item
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Budygin, E. A., P. E. Phillips, D. L. Robinson, A. P. Kennedy, R. R. Gainetdinov, and R. M. Wightman. “Effect of acute ethanol on striatal dopamine neurotransmission in ambulatory rats..” J Pharmacol Exp Ther 297, no. 1 (April 2001): 27–34.Link to Item
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Gainetdinov, R. R., and M. G. Caron. “Genetics of childhood disorders: XXIV. ADHD, part 8: hyperdopaminergic mice as an animal model of ADHD..” J Am Acad Child Adolesc Psychiatry 40, no. 3 (March 2001): 380–82. https://doi.org/10.1097/00004583-200103000-00020.Full Text Link to Item
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Sotnikova, T. D., R. R. Gainetdinov, T. V. Grekhova, and K. S. Rayevsky. “Effects of intrastriatal infusion of D2 and D3 dopamine receptor preferring antagonists on dopamine release in rat dorsal striatum (in vivo microdialysis study)..” Pharmacol Res 43, no. 3 (March 2001): 283–90. https://doi.org/10.1006/phrs.2000.0773.Full Text Link to Item
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Zhuang, X., R. S. Oosting, S. R. Jones, R. R. Gainetdinov, G. W. Miller, M. G. Caron, and R. Hen. “Hyperactivity and impaired response habituation in hyperdopaminergic mice..” Proc Natl Acad Sci U S A 98, no. 4 (February 13, 2001): 1982–87. https://doi.org/10.1073/pnas.98.4.1982.Full Text Link to Item
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Bohn, L. M., F. Xu, R. R. Gainetdinov, and M. G. Caron. “Potentiated opioid analgesia in norepinephrine transporter knock-out mice..” J Neurosci 20, no. 24 (December 15, 2000): 9040–45.Link to Item
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Bohn, L. M., R. R. Gainetdinov, F. T. Lin, R. J. Lefkowitz, and M. G. Caron. “Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence..” Nature 408, no. 6813 (December 7, 2000): 720–23. https://doi.org/10.1038/35047086.Full Text Link to Item
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Gainetdinov, R. R., R. T. Premont, M. G. Caron, and R. J. Lefkowitz. “Reply: receptor specificity of G-protein-coupled receptor kinases.” Trends Pharmacol Sci 21, no. 10 (October 2000): 366–67. https://doi.org/10.1016/s0165-6147(00)01538-8.Full Text Link to Item
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Raevskiĭ, K. S., R. R. Gaĭnetdinov, E. A. Budygin, P. Mannisto, and M. Wightman. “[Pharmacological modulation of dopaminergic transmission in the rat striatum in vivo]..” Ross Fiziol Zh Im I M Sechenova 86, no. 9 (September 2000): 1152–59.Link to Item
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Walker, J. K., R. R. Gainetdinov, A. W. Mangel, M. G. Caron, and M. A. Shetzline. “Mice lacking the dopamine transporter display altered regulation of distal colonic motility..” Am J Physiol Gastrointest Liver Physiol 279, no. 2 (August 2000): G311–18. https://doi.org/10.1152/ajpgi.2000.279.2.G311.Full Text Link to Item
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Xu, F., R. R. Gainetdinov, W. C. Wetsel, S. R. Jones, L. M. Bohn, G. W. Miller, Y. M. Wang, and M. G. Caron. “Mice lacking the norepinephrine transporter are supersensitive to psychostimulants..” Nat Neurosci 3, no. 5 (May 2000): 465–71. https://doi.org/10.1038/74839.Full Text Link to Item
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Budygin, E. A., M. R. Kilpatrick, R. R. Gainetdinov, and R. M. Wightman. “Correlation between behavior and extracellular dopamine levels in rat striatum: comparison of microdialysis and fast-scan cyclic voltammetry..” Neurosci Lett 281, no. 1 (March 3, 2000): 9–12. https://doi.org/10.1016/s0304-3940(00)00813-2.Full Text Link to Item
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Logman, M. J., E. A. Budygin, R. R. Gainetdinov, and R. M. Wightman. “Quantitation of in vivo measurements with carbon fiber microelectrodes..” J Neurosci Methods 95, no. 2 (February 15, 2000): 95–102. https://doi.org/10.1016/s0165-0270(99)00155-7.Full Text Link to Item
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Gainetdinov, R. R., and M. G. Caron. “An animal model of attention deficit hyperactivity disorder..” Mol Med Today 6, no. 1 (January 2000): 43–44. https://doi.org/10.1016/s1357-4310(99)01616-0.Full Text Link to Item
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Bohn, L. M., R. J. Lefkowitz, R. R. Gainetdinov, K. Peppel, M. G. Caron, and F. T. Lin. “Enhanced morphine analgesia in mice lacking beta-arrestin 2..” Science 286, no. 5449 (December 24, 1999): 2495–98. https://doi.org/10.1126/science.286.5449.2495.Full Text Link to Item
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Gainetdinov, R. R., L. M. Bohn, J. K. Walker, S. A. Laporte, A. D. Macrae, M. G. Caron, R. J. Lefkowitz, and R. T. Premont. “Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice..” Neuron 24, no. 4 (December 1999): 1029–36. https://doi.org/10.1016/s0896-6273(00)81048-x.Full Text Link to Item
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Huotari, M., R. Gainetdinov, and P. T. Männistö. “Microdialysis studies on the action of tolcapone on pharmacologically-elevated extracellular dopamine levels in conscious rats..” Pharmacol Toxicol 85, no. 5 (November 1999): 233–38. https://doi.org/10.1111/j.1600-0773.1999.tb02014.x.Full Text Link to Item
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Jones, S. R., R. R. Gainetdinov, and M. G. Caron. “Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity..” Psychopharmacology (Berl) 147, no. 1 (November 1999): 30–32. https://doi.org/10.1007/s002130051137.Full Text Link to Item
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Wang, Y. M., F. Xu, R. R. Gainetdinov, and M. G. Caron. “Genetic approaches to studying norepinephrine function: knockout of the mouse norepinephrine transporter gene..” Biol Psychiatry 46, no. 9 (November 1, 1999): 1124–30. https://doi.org/10.1016/s0006-3223(99)00245-0.Full Text Link to Item
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Gainetdinov, R. R., and M. G. Caron. “Delineating muscarinic receptor functions..” Proc Natl Acad Sci U S A 96, no. 22 (October 26, 1999): 12222–23. https://doi.org/10.1073/pnas.96.22.12222.Full Text Link to Item
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Miller, G. W., R. R. Gainetdinov, A. I. Levey, and M. G. Caron. “Dopamine transporters and neuronal injury..” Trends Pharmacol Sci 20, no. 10 (October 1999): 424–29. https://doi.org/10.1016/s0165-6147(99)01379-6.Full Text Link to Item
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Budygin, E. A., M. Kilpatrick, R. R. Gaĭnetdinov, K. S. Raevskiĭ, and R. M. Wightman. “[The effect of the dopamine neuronal reuptake inhibitor GBR 12909 on the dopaminergic neurotransmission parameters in the rat striatum in vivo].” Eksperimental’Naia I Klinicheskaia Farmakologiia 62, no. 5 (September 1999): 3–6.
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Mohn, A. R., R. R. Gainetdinov, M. G. Caron, and B. H. Koller. “Mice with reduced NMDA receptor expression display behaviors related to schizophrenia..” Cell 98, no. 4 (August 20, 1999): 427–36. https://doi.org/10.1016/s0092-8674(00)81972-8.Full Text Link to Item
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Gainetdinov, R. R., S. R. Jones, and M. G. Caron. “Functional hyperdopaminergia in dopamine transporter knock-out mice..” Biol Psychiatry 46, no. 3 (August 1, 1999): 303–11. https://doi.org/10.1016/s0006-3223(99)00122-5.Full Text Link to Item
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Jones, S. R., R. R. Gainetdinov, X. T. Hu, D. C. Cooper, R. M. Wightman, F. J. White, and M. G. Caron. “Loss of autoreceptor functions in mice lacking the dopamine transporter..” Nat Neurosci 2, no. 7 (July 1999): 649–55. https://doi.org/10.1038/10204.Full Text Link to Item
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Gainetdinov, R. R., and M. G. Caron. “Genetic models in pharmacology: present status and future..” Pharmacol Res 39, no. 6 (June 1999): 403–4. https://doi.org/10.1006/phrs.1999.0498.Full Text Link to Item
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Budygin, E. A., R. R. Gainetdinov, M. R. Kilpatrick, K. S. Rayevsky, P. T. Männistö, and R. M. Wightman. “Effect of tolcapone, a catechol-O-methyltransferase inhibitor, on striatal dopaminergic transmission during blockade of dopamine uptake..” Eur J Pharmacol 370, no. 2 (April 9, 1999): 125–31. https://doi.org/10.1016/s0014-2999(99)00084-9.Full Text Link to Item
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Fumagalli, F., R. R. Gainetdinov, Y. M. Wang, K. J. Valenzano, G. W. Miller, and M. G. Caron. “Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice..” J Neurosci 19, no. 7 (April 1, 1999): 2424–31.Link to Item
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Melnikova, V., M. Orosco, A. Calas, A. Sapronova, R. Gainetdinov, N. Delhaye-Bouchaud, S. Nicolaidis, K. Rayevsky, and M. Ugrumov. “Dopamine turnover in the mediobasal hypothalamus in rat fetuses..” Neuroscience 89, no. 1 (March 1999): 235–41. https://doi.org/10.1016/s0306-4522(98)00278-4.Full Text Link to Item
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Gainetdinov, R. R., W. C. Wetsel, S. R. Jones, E. D. Levin, M. Jaber, and M. G. Caron. “Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity..” Science 283, no. 5400 (January 15, 1999): 397–401. https://doi.org/10.1126/science.283.5400.397.Full Text Link to Item
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Fumagalli, F., R. R. Gainetdinov, K. J. Valenzano, and M. G. Caron. “Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter..” J Neurosci 18, no. 13 (July 1, 1998): 4861–69.Link to Item
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Rocha, B. A., F. Fumagalli, R. R. Gainetdinov, S. R. Jones, R. Ator, B. Giros, G. W. Miller, and M. G. Caron. “Cocaine self-administration in dopamine-transporter knockout mice..” Nat Neurosci 1, no. 2 (June 1998): 132–37. https://doi.org/10.1038/381.Full Text Link to Item
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Gainetdinov, R. R., F. Fumagalli, Y. M. Wang, S. R. Jones, A. I. Levey, G. W. Miller, and M. G. Caron. “Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice..” J Neurochem 70, no. 5 (May 1998): 1973–78. https://doi.org/10.1046/j.1471-4159.1998.70051973.x.Full Text Link to Item
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Gainetdinov, R. R., S. R. Jones, F. Fumagalli, R. M. Wightman, and M. G. Caron. “Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis..” Brain Res Brain Res Rev 26, no. 2–3 (May 1998): 148–53. https://doi.org/10.1016/s0165-0173(97)00063-5.Full Text Link to Item
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Jones, S. R., R. R. Gainetdinov, M. Jaber, B. Giros, R. M. Wightman, and M. G. Caron. “Profound neuronal plasticity in response to inactivation of the dopamine transporter..” Proc Natl Acad Sci U S A 95, no. 7 (March 31, 1998): 4029–34. https://doi.org/10.1073/pnas.95.7.4029.Full Text Link to Item
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Jones, S. R., R. R. Gainetdinov, R. M. Wightman, and M. G. Caron. “Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter..” J Neurosci 18, no. 6 (March 15, 1998): 1979–86.Link to Item
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Budygin, E. A., R. R. Gaĭnetdinov, K. S. Raevskiĭ, and P. T. Mannisto. “[Effect of subchronic administration of tolcapone on release of striatum dopamine and its metabolites induced by L-DOPA and carbidopa]..” Biull Eksp Biol Med 125, no. 2 (February 1998): 168–71.Link to Item
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Gainetdinov, R. R., T. D. Sotnikova, T. V. Grekhova, and K. S. Rayevsky. “Effects of a psychostimulant drug sydnocarb on rat brain dopaminergic transmission in vivo..” Eur J Pharmacol 340, no. 1 (December 4, 1997): 53–58. https://doi.org/10.1016/s0014-2999(97)01407-6.Full Text Link to Item
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Wang, Y. M., R. R. Gainetdinov, F. Fumagalli, F. Xu, S. R. Jones, C. B. Bock, G. W. Miller, R. M. Wightman, and M. G. Caron. “Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine..” Neuron 19, no. 6 (December 1997): 1285–96. https://doi.org/10.1016/s0896-6273(00)80419-5.Full Text Link to Item
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Budygin, E. A., R. R. Gaĭnetdinov, K. S. Raevskiĭ, I. H. Li, and P. T. Mannisto. “[Microdialysis study of tolcapone effect during blockage of neuronal dopamine reuptake caused by GBR-12909]..” Eksperimental’Naia I Klinicheskaia Farmakologiia 60, no. 5 (September 1997): 8–10.
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Gainetdinov, R. R., F. Fumagalli, S. R. Jones, and M. G. Caron. “Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter..” J Neurochem 69, no. 3 (September 1997): 1322–25. https://doi.org/10.1046/j.1471-4159.1997.69031322.x.Full Text Link to Item
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Bossé, R., F. Fumagalli, M. Jaber, B. Giros, R. R. Gainetdinov, W. C. Wetsel, C. Missale, and M. G. Caron. “Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter..” Neuron 19, no. 1 (July 1997): 127–38. https://doi.org/10.1016/s0896-6273(00)80353-0.Full Text Link to Item
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Budygin, E. A., R. R. Gaĭnetdinov, D. A. Titov, and G. I. Kovalev. “[Effect of aspartic acid derivatives, N-acetyl-aspartate and its phosphonic analog PIR-87-6-0, on dopamine release from the rat striatum during perfusion in vitro].” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 123, no. 1 (January 1997): 57–60.
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Raevskiĭ, K. S., T. D. Sotnikova, and R. R. Gaĭnetdinov. “[The brain dopaminergic systems: receptor heterogeneity, functional role and pharmacological regulation]..” Usp Fiziol Nauk 27, no. 4 (October 1996): 3–29.Link to Item
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Gainetdinov, R. R., T. D. Sotnikova, T. V. Grekhova, and K. S. Rayevsky. “In vivo evidence for preferential role of dopamine D3 receptor in the presynaptic regulation of dopamine release but not synthesis..” Eur J Pharmacol 308, no. 3 (July 25, 1996): 261–69. https://doi.org/10.1016/0014-2999(96)00300-7.Full Text Link to Item
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Gaĭnetdinov, R. R., and K. S. Raevskiĭ. “[Substances that increase the extracellular level of dopamine in the striatum prevent development of haloperidol catalepsy in rats].” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 121, no. 4 (April 1996): 438–40.
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Sotnikova, T. D., R. R. Gaĭnetdinov, T. V. Grekhova, and K. S. Raevskiĭ. “[Dopamine autoreceptors subtype D3 predominantly regulate the liberation of dopamine in rat brain basal ganglia]..” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 121, no. 4 (April 1996): 430–34.
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Budygin, E. A., R. R. Gaĭnetdinov, D. A. Titov, and G. I. Kovalev. “[The effect of a low dose of piracetam on the activity of the dopaminergic system in the rat striatum]..” Eksp Klin Farmakol 59, no. 2 (March 1996): 6–8.Link to Item
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Gainetdinov, R. R., T. D. Sotnikova, T. V. Grekhova, and K. S. Rayevsky. “Simultaneous monitoring of dopamine, its metabolites and trans-isomer of atypical neuroleptic drug carbidine concentrations in striatal dialysates of conscious rats..” Prog Neuropsychopharmacol Biol Psychiatry 20, no. 2 (February 1996): 291–305. https://doi.org/10.1016/0278-5846(95)00311-8.Full Text Link to Item
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Rayevsky, K. S., R. R. Gainetdinov, T. V. Grekhova, and T. D. Sotnikova. “Regulation of dopamine release and metabolism in rat striatum in vivo: effects of dopamine receptor antagonists..” Prog Neuropsychopharmacol Biol Psychiatry 19, no. 8 (December 1995): 1285–1303. https://doi.org/10.1016/0278-5846(95)00267-7.Full Text Link to Item
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Salimov, R. M., I. I. Poletaeva, G. I. Kovalev, N. B. Salimova, and R. R. Gaĭnetdinov. “[Interstrain differences in extrapolation capacity and exploration of a cruciform maze correlate with various indices of monoamine metabolism in the brain]..” Zh Vyssh Nerv Deiat Im I P Pavlova 45, no. 5 (September 1995): 914–24.Link to Item
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Kudrin, V. S., S. A. Sergeeva, L. M. Krasnykh, I. I. Miroshnichenko, T. V. Grekhova, and R. R. Gaĭnetdinov. “[The effect of bromantane on the dopamin- and serotoninergic systems of the rat brain]..” Eksperimental’Naia I Klinicheskaia Farmakologiia 58, no. 4 (July 1995): 8–11.
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Gainetdinov, R. R., T. D. Sotnikova, T. V. Grekhova, and K. S. Rayevsky. “Estimation of the interstitial free concentration of the putative dopamine D3 receptor selective agonist 7-OH-DPAT in the dorsal striatum of freely moving rats..” Neurosci Lett 193, no. 1 (June 23, 1995): 65–67. https://doi.org/10.1016/0304-3940(95)11653-e.Full Text Link to Item
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Grekhova, T. V., R. R. Gaĭnetdinov, T. D. Sotnikova, L. M. Krasnykh, V. S. Kudrin, S. A. Sergeeva, and I. S. Morozov. “[The effect of bromantane, a new immunostimulant with psychostimulating action, on release and metabolism of dopamine in the dorsal striatum of freely moving rats: a microdialysis study]..” Biull Eksp Biol Med 119, no. 3 (March 1995): 302–4.Link to Item
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Gainetdinov, R. R., T. V. Grekhova, T. D. Sotnikova, and K. S. Rayevsky. “Dopamine D2 and D3 receptor preferring antagonists differentially affect striatal dopamine release and metabolism in conscious rats..” Eur J Pharmacol 261, no. 3 (August 22, 1994): 327–31. https://doi.org/10.1016/0014-2999(94)90125-2.Full Text Link to Item
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Gaĭnetdinov, R. R., T. D. Sotnikova, T. V. Grekhova, and K. S. Raevskiĭ. “[Regulation of liberation and metabolism of dopamine in the dorsal striatum of free-living rats: the role of D2- and D3-dopamine autoreceptors]..” Dokl Akad Nauk 337, no. 6 (August 1994): 821–23.Link to Item
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Guinetdinov, R. R., M. B. Bogdanov, V. S. Kudrin, and K. S. Rayevsky. “Remoxipride and raclopride differ from metoclopramide by their effects on striatal dopamine release and biosynthesis in rats..” Neuropharmacology 33, no. 2 (February 1994): 215–19. https://doi.org/10.1016/0028-3908(94)90011-6.Full Text Link to Item
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Kovalev, G. I., E. A. Budygin, R. R. Gaĭnetdinov, V. S. Kudrin, S. S. Trofimov, and R. U. Ostrovskaia. “[The sodium oxybutyrate and nooglutil correction of dopamine release in the striatum of prenatally alcoholized rat pups]..” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 116, no. 7 (July 1993): 56–58.
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Grekhova, T. V., G. A. Romanova, R. R. Gaĭnetdinov, V. S. Kudrin, and K. S. Raevskiĭ. “[Effects of N-acetylasparaginic acid during frontal lobectomy in the rat: antiamnestic action and effect on monoamine level].” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 115, no. 2 (February 1993): 159–61.
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Gaĭnetdinov, R. R., I. I. Miroshnichenko, V. S. Kudrin, M. B. Bogdanov, V. M. Pogorelov, E. A. Budygin, G. I. Kovalev, and K. S. Raevskiĭ. “[A comparative study of the neurochemical profiles of carbidine stereoisomers]..” Eksp Klin Farmakol 56, no. 1 (January 1993): 24–27.Link to Item
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Gaĭnetdinov, R. R., A. I. Gromov, V. S. Kudrin, and M. S. Pletnikov. “[Effects of haloperidol on extracellular contents of dopamine and its metabolites in the septum of rats during interspecies aggression].” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 114, no. 9 (September 1992): 231–33.
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Gaĭnetdinov, R. R., E. A. Budygin, G. I. Kovalev, V. S. Kudrin, and K. S. Raevskiĭ. “[Different effects of typical and atypical neuroleptics on K+-stimulated dopamine release from isolated rat striatum]..” Biull Eksp Biol Med 114, no. 7 (July 1992): 47–49.Link to Item
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Gaĭnetdinov, R. R., M. B. Bogdanov, V. S. Kudrin, E. A. Budygin, G. I. Kovalev, and K. S. Raevskiĭ. “[A comparative study of the neurochemical profiles of remoxipride, raclopride and metoclopramide activity].” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 114, no. 8 (July 1992): 165–68.
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Gaĭnetdinov, R. R., M. B. Bogdanov, V. S. Kudrin, and K. S. Raevskiĭ. “[Selective analyzers of dopamine D2 receptors modulate serotonin metabolism in the striatum and nucleus accumbens of the rat brain during blockade of dopaminergic impulse flow].” Biulleten’ Eksperimental’Noi Biologii I Meditsiny 113, no. 6 (June 1992): 614–16.
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Gaĭnetdinov, R. R., A. I. Gromov, V. S. Kudrin, and M. V. Pletnikov. “[Changes in the content of extracellular dopamine and its metabolites in the septum of freely moving rats in the act of interspecific aggression]..” Zh Vyssh Nerv Deiat Im I P Pavlova 42, no. 3 (May 1992): 597–99.Link to Item
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Trofimov, S. S., R. U. Ostrovskaia, N. M. Smol’nikova, I. V. Khromova, S. V. Krapivin, A. M. Krylova, G. I. Kovalev, R. R. Gaĭnetdinov, B. I. Liubimov, and T. A. Voronina. “[The nooglutil correction of functional disorders of the central nervous system caused by prenatal alcoholization in rats]..” Eksperimental’Naia I Klinicheskaia Farmakologiia 55, no. 1 (January 1992): 18–21.
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Guinetdinov, R. R., M. B. Bogdanov, V. M. Pogorelov, V. S. Kudrin, and K. S. Rayevsky. “Stereoisomers of the atypical neuroleptic carbidine modulate striatal dopamine release in awake rats..” Neuropharmacology 30, no. 11 (November 1991): 1251–54. https://doi.org/10.1016/0028-3908(91)90173-9.Full Text Link to Item
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Osniach, V. S., V. S. Kudrin, R. R. Gaĭnetdinov, and P. V. Sergeev. “[The effect of low doses of radiation on the monoamine level in rat hypothalamus (with and without a gas-hypoxic mixture)]..” Biull Eksp Biol Med 112, no. 10 (October 1991): 432–33.Link to Item
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Bogdanov, M. B., R. R. Gaĭnetdinov, V. S. Kudrin, O. S. Medvedev, and A. V. Val’dman. “[Study by the intracerebral microdialysis method of the effects of atypical neuroleptics and anxiolytics on striatal release and metabolism of dopamine in awake rats]..” Biull Eksp Biol Med 111, no. 5 (May 1991): 505–7.Link to Item
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Gaĭnetdinov, R. R., A. I. Gromov, and V. S. Kudrin. “[The extracellular content of dopamine, its metabolites and 5-hydroxyindoleacetic acid in the amygdala of free-moving rats during an act of interspecific aggression]..” Zh Vyssh Nerv Deiat Im I P Pavlova 41, no. 3 (May 1991): 584–86.Link to Item
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