Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Northwestern University 2003
• 

  Duke Appointment History

  • Assistant Professor of Radiology, Radiology, Abdominal Imaging, Radiology 2010 - 2016
  • Medical Instructor in the Department of Radiology, Radiology, Abdominal Imaging, Radiology 2009 - 2010
  • Clinical Associate in the Department of Radiology, Radiology, Abdominal Imaging, Radiology 2008 - 2009
• 

  Leadership & Clinical Positions at Duke

  • Division Chief, Abdominal Imaging
    
    Director of Imaging, Duke Cancer Institute Center for Prostate & Urologic Cancers

    Director, Duke Radiology Continuing Medical Education
• Recognition
• 

  In the News

  • JAN 5, 2015

    WRAL

    New imaging detects more prostate tumors
• Research
• 

  Selected Grants

  • Image guided targeted biopsy of clinically significant prostate cancer with acoustic radiation force awarded by National Institutes of Health 2010 - 2022
  • Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) of Bone Marrow In Acute Myeloid Leukemia 2014 - 2019
  • Prostate Cancer Assessment and Treatment Guidance Via Integrated 3D ARFI Elasticity Imaging and Multi-Parametric MRI 2015 - 2016
• 

  Industry Relationships

  • Bard
  • Bayer Schering Pharma AG
  • Invivo (Phillips)
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Sze, Christina, Efrat Tsivian, Kae Jack Tay, Ariel A. Schulman, Leah G. Davis, Rajan T. Gupta, and Thomas J. Polascik. “Anterior gland focal cryoablation: proof-of-concept primary prostate cancer treatment in select men with localized anterior cancers detected by multi-parametric magnetic resonance imaging..” Bmc Urol 19, no. 1 (December 5, 2019). https://doi.org/10.1186/s12894-019-0562-5.
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    • Potretzke, Theodora A., Adam T. Froemming, and Rajan T. Gupta. “Post-treatment prostate MRI..” Abdom Radiol (Ny), December 2, 2019. https://doi.org/10.1007/s00261-019-02348-x.
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    • Expert Panel on Urological Imaging, Mark E., Andrei S. Purysko, Paul Nikolaidis, Vikram S. Dogra, Dhakshinamoorthy Ganeshan, John L. Gore, Rajan T. Gupta, et al. “ACR Appropriateness Criteria® Post-Treatment Follow-up and Active Surveillance of Clinically Localized Renal Cell Cancer..” J Am Coll Radiol 16, no. 11S (November 2019): S399–416. https://doi.org/10.1016/j.jacr.2019.05.022.
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    • Zhu, Jason, Matthew Tucker, Daniele Marin, Rajan T. Gupta, Patrick Healy, Michael Humeniuk, Casey Jarvis, et al. “Clinical utility of FoundationOne tissue molecular profiling in men with metastatic prostate cancer..” Urol Oncol 37, no. 11 (November 2019): 813.e1-813.e9. https://doi.org/10.1016/j.urolonc.2019.06.015.
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    • Gupta, Rajan T., Kurren A. Mehta, Baris Turkbey, and Sadhna Verma. “PI-RADS: Past, present, and future..” J Magn Reson Imaging, August 8, 2019. https://doi.org/10.1002/jmri.26896.
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    • Tucker, Matthew D., Jason Zhu, Daniele Marin, Rajan T. Gupta, Santosh Gupta, William R. Berry, Sundhar Ramalingam, et al. “Pembrolizumab in men with heavily treated metastatic castrate-resistant prostate cancer..” Cancer Med 8, no. 10 (August 2019): 4644–55. https://doi.org/10.1002/cam4.2375.
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    • Vernuccio, Federica, Roberto Cannella, Mathias Meyer, Kingshuk Roy Choudhoury, Fernando Gonzáles, Fides R. Schwartz, Rajan T. Gupta, Mustafa R. Bashir, Alessandro Furlan, and Daniele Marin. “LI-RADS: Diagnostic Performance of Hepatobiliary Phase Hypointensity and Major Imaging Features of LR-3 and LR-4 Lesions Measuring 10-19 mm With Arterial Phase Hyperenhancement..” Ajr Am J Roentgenol 213, no. 2 (August 2019): W57–65. https://doi.org/10.2214/AJR.18.20979.
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    • Gupta, Rajan T., Robert S. Saunders, Andrew B. Rosenkrantz, Erik K. Paulson, and Ehsan Samei. “The Need for Practical and Accurate Measures of Value for Radiology..” J Am Coll Radiol 16, no. 6 (June 2019): 810–13. https://doi.org/10.1016/j.jacr.2018.11.013.
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    • Kao, Chester, Megan McNamara, Chris Alley, Neil Spector, Shekeab Jauhari, Rajan T. Gupta, Tian Zhang, and Jason Zhu. “A Complete Response After Pseudo-progression: Pembrolizumab for Metastatic Squamous Cell Carcinoma (SCC) of the Bladder..” Clin Genitourin Cancer 17, no. 3 (June 2019): e672–77. https://doi.org/10.1016/j.clgc.2019.03.019.
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    • Wang, Yingqi, Andrew Chang, Wei Phin Tan, Joseph J. Fantony, Ajay Gopalakrishna, Gregory J. Barton, Paul E. Wischmeyer, Rajan T. Gupta, and Brant A. Inman. “Diet and Exercise Are not Associated with Skeletal Muscle Mass and Sarcopenia in Patients with Bladder Cancer..” Eur Urol Oncol, May 25, 2019. https://doi.org/10.1016/j.euo.2019.04.012.
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    • Patel, Hiten D., Maneka Puligandla, Brian M. Shuch, Bradley C. Leibovich, Anil Kapoor, Viraj A. Master, Charles G. Drake, et al. “The future of perioperative therapy in advanced renal cell carcinoma: how can we PROSPER?.” Future Oncol 15, no. 15 (May 2019): 1683–95. https://doi.org/10.2217/fon-2018-0951.
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    • Sexton, Stephanie J., Garjae Lavien, Nicholas Said, William Eward, Andrew C. Peterson, and Rajan T. Gupta. “Magnetic resonance imaging features of pubic symphysis urinary fistula with pubic bone osteomyelitis in the treated prostate cancer patient..” Abdom Radiol (Ny) 44, no. 4 (April 2019): 1453–60. https://doi.org/10.1007/s00261-018-1827-2.
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    • Aminsharifi, Alireza, Rajan T. Gupta, Efrat Tsivian, Sitharthan Sekar, Christina Sze, and Thomas J. Polascik. “Reduced Core Targeted (RCT) biopsy: Combining multiparametric magnetic resonance imaging - transrectal ultrasound fusion targeted biopsy with laterally-directed sextant biopsies - An alternative template for prostate fusion biopsy..” Eur J Radiol 110 (January 2019): 7–13. https://doi.org/10.1016/j.ejrad.2018.11.006.
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    • Gaur, Sonia, Stephanie Harmon, Rajan T. Gupta, Daniel J. Margolis, Nathan Lay, Sherif Mehralivand, Maria J. Merino, et al. “A Multireader Exploratory Evaluation of Individual Pulse Sequence Cancer Detection on Prostate Multiparametric Magnetic Resonance Imaging (MRI)..” Acad Radiol 26, no. 1 (January 2019): 5–14. https://doi.org/10.1016/j.acra.2018.03.024.
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    • Sullivan, Brian, Jonathan Glaab, Rajan T. Gupta, Richard Wood, and David A. Leiman. “Lymphogranuloma venereum (LGV) proctocolitis mimicking rectal lymphoma..” Radiol Case Rep 13, no. 6 (December 2018): 1119–22. https://doi.org/10.1016/j.radcr.2018.08.015.
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    • Aminsharifi, Alireza, Rajan T. Gupta, Jiaoti Huang, and Thomas J. Polascik. “Three-dimensional localization and targeting of prostate cancer foci with imaging and histopathologic correlation: establishing a multidisciplinary team for quality improvement..” Curr Opin Urol 28, no. 6 (November 2018): 506–11. https://doi.org/10.1097/MOU.0000000000000554.
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    • Wollin, Daniel A., Rajan T. Gupta, Brian Young, Eugene Cone, Adam Kaplan, Daniele Marin, Bhavik N. Patel, et al. “Abdominal Radiography With Digital Tomosynthesis: An Alternative to Computed Tomography for Identification of Urinary Calculi?.” Urology 120 (October 2018): 56–61. https://doi.org/10.1016/j.urology.2018.06.041.
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    • Gaur, Sonia, Nathan Lay, Stephanie A. Harmon, Sreya Doddakashi, Sherif Mehralivand, Burak Argun, Tristan Barrett, et al. “Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation..” Oncotarget 9, no. 73 (September 18, 2018): 33804–17. https://doi.org/10.18632/oncotarget.26100.
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    • Duvnjak, Petar, Ariel A. Schulman, Jamie N. Holtz, Jiaoti Huang, Thomas J. Polascik, and Rajan T. Gupta. “Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making..” Urol Clin North Am 45, no. 3 (August 2018): 455–66. https://doi.org/10.1016/j.ucl.2018.03.010.
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    • Mull, Hillary J., Ziad F. Gellad, Rajan T. Gupta, Javier A. Valle, Danil V. Makarov, Tyler Silverman, and Westyn Branch-Elliman. “Factors Associated With Emergency Department Visits and Hospital Admissions After Invasive Outpatient Procedures in the Veterans Health Administration..” Jama Surg 153, no. 8 (August 1, 2018): 774–76. https://doi.org/10.1001/jamasurg.2018.0874.
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    • Gupta, Rajan T., and Andrew B. Rosenkrantz. “Prostate MRI can be accurate but can variability be reduced?.” Nat Rev Urol 15, no. 6 (June 2018): 339–40. https://doi.org/10.1038/s41585-018-0002-4.
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    • Ronald, James, Rajan T. Gupta, Daniele Marin, Qi Wang, Nicholas S. Durocher, Paul V. Suhocki, and Charles Y. Kim. “Progression of Treated versus Untreated Liver Imaging Reporting and Data System Category 4 Masses after Transcatheter Arterial Embolization Therapy..” J Vasc Interv Radiol 29, no. 5 (May 2018): 598–606. https://doi.org/10.1016/j.jvir.2017.11.027.
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    • Humeniuk, Michael S., Rajan T. Gupta, Patrick Healy, Megan McNamara, Sundhar Ramalingam, Michael Harrison, Daniel George, Tian Zhang, Yuan Wu, and Andrew J. Armstrong. “Platinum sensitivity in metastatic prostate cancer: does histology matter?.” Prostate Cancer Prostatic Dis 21, no. 1 (April 2018): 92–99. https://doi.org/10.1038/s41391-017-0017-6.
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    • Duvnjak, Petar, Ariel A. Schulman, Jamie N. Holtz, Jiaoti Huang, Thomas J. Polascik, and Rajan T. Gupta. “Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making..” Radiol Clin North Am 56, no. 2 (March 2018): 239–50. https://doi.org/10.1016/j.rcl.2017.10.007.
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    • Holtz, Jamie N., Rachel Kloss Silverman, Kae Jack Tay, Jill T. Browning, Jiaoti Huang, Thomas J. Polascik, and Rajan T. Gupta. “New prostate cancer prognostic grade group (PGG): Can multiparametric MRI (mpMRI) accurately separate patients with low-, intermediate-, and high-grade cancer?.” Abdom Radiol (Ny) 43, no. 3 (March 2018): 702–12. https://doi.org/10.1007/s00261-017-1255-8.
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    • Kambadakone, Avinash R., Alice Fung, Rajan T. Gupta, Thomas A. Hope, Kathryn J. Fowler, Andrej Lyshchik, Karthik Ganesan, et al. “LI-RADS technical requirements for CT, MRI, and contrast-enhanced ultrasound..” Abdom Radiol (Ny) 43, no. 1 (January 2018): 56–74. https://doi.org/10.1007/s00261-017-1325-y.
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    • Kambadakone, Avinash R., Alice Fung, Rajan T. Gupta, Thomas A. Hope, Kathryn J. Fowler, Andrej Lyshchik, Karthik Ganesan, et al. “Correction to: LI-RADS technical requirements for CT, MRI, and contrast-enhanced ultrasound..” Abdom Radiol (Ny) 43, no. 1 (January 2018). https://doi.org/10.1007/s00261-017-1345-7.
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    • Ronald, James, Andrew B. Nixon, Daniele Marin, Rajan T. Gupta, Gemini Janas, Willa Chen, Paul V. Suhocki, et al. “Pilot Evaluation of Angiogenesis Signaling Factor Response after Transcatheter Arterial Embolization for Hepatocellular Carcinoma..” Radiology 285, no. 1 (October 2017): 311–18. https://doi.org/10.1148/radiol.2017162555.
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    • Marin, Daniele, Drew Davis, Kingshuk Roy Choudhury, Bhavik Patel, Rajan T. Gupta, Achille Mileto, and Rendon C. Nelson. “Characterization of Small Focal Renal Lesions: Diagnostic Accuracy with Single-Phase Contrast-enhanced Dual-Energy CT with Material Attenuation Analysis Compared with Conventional Attenuation Measurements..” Radiology 284, no. 3 (September 2017): 737–47. https://doi.org/10.1148/radiol.2017161872.
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    • Tay, K. J., R. T. Gupta, J. Holtz, R. K. Silverman, E. Tsivian, A. Schulman, J. W. Moul, and T. J. Polascik. “Does mpMRI improve clinical criteria in selecting men with prostate cancer for active surveillance?.” Prostate Cancer Prostatic Dis 20, no. 3 (September 2017): 323–27. https://doi.org/10.1038/pcan.2017.20.
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    • Harshman, L. C., C. G. Drake, N. B. Haas, J. Manola, M. Puligandla, S. Signoretti, D. Cella, et al. “Transforming the Perioperative Treatment Paradigm in Non-Metastatic RCC-A Possible Path Forward..” Kidney Cancer 1, no. 1 (July 26, 2017): 31–40. https://doi.org/10.3233/KCA-170010.
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    • Dale, Joanne, Rajan T. Gupta, Daniele Marin, Michael Lipkin, and Glenn Preminger. “Imaging Advances in Urolithiasis..” J Endourol 31, no. 7 (July 2017): 623–29. https://doi.org/10.1089/end.2016.0695.
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    • Schulman, Ariel A., Christina Sze, Efrat Tsivian, Rajan T. Gupta, Judd W. Moul, and Thomas J. Polascik. “The Contemporary Role of Multiparametric Magnetic Resonance Imaging in Active Surveillance for Prostate Cancer..” Curr Urol Rep 18, no. 7 (July 2017). https://doi.org/10.1007/s11934-017-0699-2.
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    • Scheltema, M. J., K. J. Tay, A. W. Postema, D. M. de Bruin, J. Feller, J. J. Futterer, A. K. George, et al. “Utilization of multiparametric prostate magnetic resonance imaging in clinical practice and focal therapy: report from a Delphi consensus project..” World J Urol 35, no. 5 (May 2017): 695–701. https://doi.org/10.1007/s00345-016-1932-1.
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    • Tsivian, Matvey, Rajan T. Gupta, Efrat Tsivian, Peter Qi, Melissa H. Mendez, Michael R. Abern, Kae Jack Tay, and Thomas J. Polascik. “Assessing clinically significant prostate cancer: Diagnostic properties of multiparametric magnetic resonance imaging compared to three-dimensional transperineal template mapping histopathology..” Int J Urol 24, no. 2 (February 2017): 137–43. https://doi.org/10.1111/iju.13251.
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    • Holtz, Jamie N., Kae Jack Tay, Thomas J. Polascik, and Rajan T. Gupta. “Integration of multiparametric MRI into active surveillance of prostate cancer..” Future Oncol 12, no. 21 (November 2016): 2513–29. https://doi.org/10.2217/fon-2016-0142.
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    • Postema, A. W., T. M. De Reijke, O. Ukimura, W. Van den Bos, A. R. Azzouzi, E. Barret, D. Baumunk, et al. “Standardization of definitions in focal therapy of prostate cancer: report from a Delphi consensus project..” World J Urol 34, no. 10 (October 2016): 1373–82. https://doi.org/10.1007/s00345-016-1782-x.
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    • Rosenkrantz, Andrew B., Luke A. Ginocchio, Daniel Cornfeld, Adam T. Froemming, Rajan T. Gupta, Baris Turkbey, Antonio C. Westphalen, James S. Babb, and Daniel J. Margolis. “Interobserver Reproducibility of the PI-RADS Version 2 Lexicon: A Multicenter Study of Six Experienced Prostate Radiologists..” Radiology 280, no. 3 (September 2016): 793–804. https://doi.org/10.1148/radiol.2016152542.
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    • Heye, T., E. M. Merkle, J. R. Leyendecker, D. T. Boll, and R. T. Gupta. “Portrayal of radiology in a major medical television series: How does it influence the perception of radiology among patients and radiology professionals?.” Eur Radiol 26, no. 8 (August 2016): 2863–69. https://doi.org/10.1007/s00330-015-4079-3.
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    • Tay, Kae Jack, Rajan T. Gupta, Alison F. Brown, Rachel K. Silverman, and Thomas J. Polascik. “Defining the Incremental Utility of Prostate Multiparametric Magnetic Resonance Imaging at Standard and Specialized Read in Predicting Extracapsular Extension of Prostate Cancer..” Eur Urol 70, no. 2 (August 2016): 211–13. https://doi.org/10.1016/j.eururo.2015.10.041.
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    • Gupta, Rajan T., Alison Flanagan Brown, Rachel Kloss Silverman, Kae Jack Tay, John F. Madden, Daniel J. George, and Thomas J. Polascik. “Can Radiologic Staging With Multiparametric MRI Enhance the Accuracy of the Partin Tables in Predicting Organ-Confined Prostate Cancer?.” Ajr Am J Roentgenol 207, no. 1 (July 2016): 87–95. https://doi.org/10.2214/AJR.15.15878.
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    • Griffin, Andrew S., Matthew D. Crawford, and Rajan T. Gupta. “Massive gas gangrene secondary to occult colon carcinoma..” Radiol Case Rep 11, no. 2 (June 2016): 67–69. https://doi.org/10.1016/j.radcr.2016.02.006.
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    • Palmeri, Mark L., Tyler J. Glass, Zachary A. Miller, Stephen J. Rosenzweig, Andrew Buck, Thomas J. Polascik, Rajan T. Gupta, Alison F. Brown, John Madden, and Kathryn R. Nightingale. “Identifying Clinically Significant Prostate Cancers using 3-D In Vivo Acoustic Radiation Force Impulse Imaging with Whole-Mount Histology Validation..” Ultrasound Med Biol 42, no. 6 (June 2016): 1251–62. https://doi.org/10.1016/j.ultrasmedbio.2016.01.004.
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    • Ramalingam, Sundhar, David J. Sermer, Rajan Gupta, Patrick Healy, Yuan Wu, Daniel J. George, Andrew J. Armstrong, and Michael Roger Harrison. “Changes in skeletal muscle cross sectional area (CSA) in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide (ENZ)..” Journal of Clinical Oncology 34, no. 15_suppl (May 20, 2016): e16601–e16601. https://doi.org/10.1200/jco.2016.34.15_suppl.e16601.
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    • Gupta, Rajan T., Benjamin Spilseth, Nayana Patel, Alison F. Brown, and Jinxing Yu. “Multiparametric prostate MRI: focus on T2-weighted imaging and role in staging of prostate cancer..” Abdom Radiol (Ny) 41, no. 5 (May 2016): 831–43. https://doi.org/10.1007/s00261-015-0579-5.
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    • Gupta, Rajan T., Benjamin Spilseth, and Adam T. Froemming. “How and why a generation of radiologists must be trained to accurately interpret prostate mpMRI..” Abdom Radiol (Ny) 41, no. 5 (May 2016): 803–4. https://doi.org/10.1007/s00261-016-0745-4.
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    • Tay, Kae Jack, Rajan T. Gupta, Ardeshir R. Rastinehad, Efrat Tsivian, Stephen J. Freedland, Judd W. Moul, and Thomas J. Polascik. “Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls..” Expert Rev Anticancer Ther 16, no. 3 (2016): 303–11. https://doi.org/10.1586/14737140.2016.1131155.
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    • Marin, Daniele, Achille Mileto, Rajan T. Gupta, Lisa M. Ho, Brian C. Allen, Kingshuk Roy Choudhury, and Rendon C. Nelson. “Effect of radiologists' experience with an adaptive statistical iterative reconstruction algorithm on detection of hypervascular liver lesions and perception of image quality..” Abdom Imaging 40, no. 7 (October 2015): 2850–60. https://doi.org/10.1007/s00261-015-0398-8.
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    • Patel, Bhavik N., Rajan T. Gupta, Sabino Zani, R Brooke Jeffrey, Erik K. Paulson, and Rendon C. Nelson. “How the radiologist can add value in the evaluation of the pre- and post-surgical pancreas..” Abdom Imaging 40, no. 8 (October 2015): 2932–44. https://doi.org/10.1007/s00261-015-0549-y.
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    • Gupta, Rajan T., Christopher R. Kauffman, Kirema Garcia-Reyes, Mark L. Palmeri, John F. Madden, Thomas J. Polascik, and Andrew B. Rosenkrantz. “Apparent Diffusion Coefficient Values of the Benign Central Zone of the Prostate: Comparison With Low- and High-Grade Prostate Cancer..” Ajr Am J Roentgenol 205, no. 2 (August 2015): 331–36. https://doi.org/10.2214/AJR.14.14221.
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    • Feuerlein, S., M. S. Davenport, A. Krishnaraj, E. M. Merkle, and R. T. Gupta. “Computed high b-value diffusion-weighted imaging improves lesion contrast and conspicuity in prostate cancer..” Prostate Cancer Prostatic Dis 18, no. 2 (June 2015): 155–60. https://doi.org/10.1038/pcan.2015.5.
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    • Lauenstein, Thomas, Francisco Ramirez-Garrido, Young Hoon Kim, Sung Eun Rha, Jens Ricke, Sith Phongkitkarun, Joachim Boettcher, et al. “Nephrogenic systemic fibrosis risk after liver magnetic resonance imaging with gadoxetate disodium in patients with moderate to severe renal impairment: results of a prospective, open-label, multicenter study..” Invest Radiol 50, no. 6 (June 2015): 416–22. https://doi.org/10.1097/RLI.0000000000000145.
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    • Mendez, Melissa H., Daniel Y. Joh, Rajan Gupta, and Thomas J. Polascik. “Current trends and new frontiers in focal therapy for localized prostate cancer..” Curr Urol Rep 16, no. 6 (June 2015). https://doi.org/10.1007/s11934-015-0513-y.
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    • Grady, A. T., J. A. Sosa, T. P. Tanpitukpongse, K. R. Choudhury, R. T. Gupta, and J. K. Hoang. “Radiology reports for incidental thyroid nodules on CT and MRI: high variability across subspecialties..” Ajnr Am J Neuroradiol 36, no. 2 (February 2015): 397–402. https://doi.org/10.3174/ajnr.A4089.
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    • Garcia-Reyes, Kirema, Niccolò M. Passoni, Mark L. Palmeri, Christopher R. Kauffman, Kingshuk Roy Choudhury, Thomas J. Polascik, and Rajan T. Gupta. “Detection of prostate cancer with multiparametric MRI (mpMRI): effect of dedicated reader education on accuracy and confidence of index and anterior cancer diagnosis..” Abdom Imaging 40, no. 1 (January 2015): 134–42. https://doi.org/10.1007/s00261-014-0197-7.
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    • Gupta, Rajan T., J Bryan Sexton, Judy Milne, and Donald P. Frush. “Practice and quality improvement: successful implementation of TeamSTEPPS tools into an academic interventional ultrasound practice..” Ajr Am J Roentgenol 204, no. 1 (January 2015): 105–10. https://doi.org/10.2214/AJR.14.12775.
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    • Palmeri, Mark L., Zachary A. Miller, Tyler J. Glass, Kirema Garcia-Reyes, Rajan T. Gupta, Stephen J. Rosenzweig, Christopher Kauffman, et al. “B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging..” Ultrason Imaging 37, no. 1 (January 2015): 22–41. https://doi.org/10.1177/0161734614542177.
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    • Gupta, R. T., T. J. Polascik, S. S. Taneja, and A. B. Rosenkrantz. “Recent Developments in Multiparametric Prostate MR Imaging.” Current Radiology Reports 2, no. 12 (December 14, 2014). https://doi.org/10.1007/s40134-014-0074-8.
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    • Gupta, Rajan T., Kamil F. Faridi, Abhay A. Singh, Niccolò M. Passoni, Kirema Garcia-Reyes, John F. Madden, and Thomas J. Polascik. “Comparing 3-T multiparametric MRI and the Partin tables to predict organ-confined prostate cancer after radical prostatectomy..” Urol Oncol 32, no. 8 (November 2014): 1292–99. https://doi.org/10.1016/j.urolonc.2014.04.017.
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    • Bashir, Mustafa R., Rekha Mody, Amy Neville, Ramin Javan, Danielle Seaman, Charles Y. Kim, Rajan T. Gupta, and Tracy A. Jaffe. “Retrospective assessment of the utility of an iron-based agent for contrast-enhanced magnetic resonance venography in patients with endstage renal diseases..” J Magn Reson Imaging 40, no. 1 (July 2014): 113–18. https://doi.org/10.1002/jmri.24330.
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    • Muller, Berrend G., Jurgen J. Fütterer, Rajan T. Gupta, Aaron Katz, Alexander Kirkham, John Kurhanewicz, Judd W. Moul, et al. “The role of magnetic resonance imaging (MRI) in focal therapy for prostate cancer: recommendations from a consensus panel..” Bju Int 113, no. 2 (February 2014): 218–27. https://doi.org/10.1111/bju.12243.
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    • Marin, Daniele, Kingshuk Roy Choudhury, Rajan T. Gupta, Lisa M. Ho, Brian C. Allen, Sebastian T. Schindera, James G. Colsher, Ehsan Samei, and Rendon C. Nelson. “Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique..” Eur Radiol 23, no. 12 (December 2013): 3325–35. https://doi.org/10.1007/s00330-013-2964-1.
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    • Bashir, Mustafa R., Xiaodong Zhong, Brian M. Dale, Rajan T. Gupta, Daniel T. Boll, and Elmar M. Merkle. “Automated patient-tailored screening of the liver for diffuse steatosis and iron overload using MRI..” Ajr Am J Roentgenol 201, no. 3 (September 2013): 583–88. https://doi.org/10.2214/AJR.12.10051.
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    • Bhargava, Puneet, Ramesh S. Iyer, Mariam Moshiri, Matthew M. Yeh, Melissa P. Upton, Wen-Chi Foo, Lorenzo Mannelli, and Rajan T. Gupta. “Radiologic-pathologic correlation of uncommon mesenchymal liver tumors..” Curr Probl Diagn Radiol 42, no. 5 (September 2013): 183–90. https://doi.org/10.1067/j.cpradiol.2013.05.002.
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    • Huang, Steven Y., Charles Y. Kim, Michael J. Miller, Rajan T. Gupta, Mark L. Lessne, Jeffrey J. Horvath, Daniel T. Boll, et al. “Abdominopelvic and lower extremity deep venous thrombosis: evaluation with contrast-enhanced MR venography with a blood-pool agent..” Ajr Am J Roentgenol 201, no. 1 (July 2013): 208–14. https://doi.org/10.2214/AJR.12.9611.
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    • Reiner, Caecilia S., Elmar M. Merkle, Mustafa R. Bashir, Nicholas L. Walle, Hamid K. Nazeer, and Rajan T. Gupta. “MRI assessment of biliary ductal obstruction: is there added value of T1-weighted gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced MR cholangiography?.” Ajr Am J Roentgenol 201, no. 1 (July 2013): W49–56. https://doi.org/10.2214/AJR.12.9332.
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    • Allen, Brian C., Mustafa R. Bashir, Brian M. Dale, Tobias J. Heye, Rajan T. Gupta, and Elmar M. Merkle. “Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis..” J Comput Assist Tomogr 37, no. 3 (May 2013): 458–62. https://doi.org/10.1097/RCT.0b013e318283d549.
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    • Gupta, R. T., C. R. Kauffman, T. J. Polascik, S. S. Taneja, and A. B. Rosenkrantz. “The state of prostate MRI in 2013..” Oncology (Williston Park, N.Y.) 27, no. 4 (April 1, 2013): 262–70.
    • Gupta, Rajan T., Christopher R. Kauffman, Thomas J. Polascik, Samir S. Taneja, and Andrew B. Rosenkrantz. “The state of prostate MRI in 2013..” Oncology (Williston Park) 27, no. 4 (April 2013): 262–70.
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    • Ringe, Kristina I., Daniel T. Boll, Daniela B. Husarik, Mustafa R. Bashir, Rajan T. Gupta, and Elmar M. Merkle. “Lesion detection and assessment of extrahepatic findings in abdominal MRI using hepatocyte specific contrast agents--comparison of Gd-EOB-DTPA and Gd-BOPTA..” Bmc Med Imaging 13 (March 18, 2013). https://doi.org/10.1186/1471-2342-13-10.
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    • Breault, Steven R., Tobias Heye, Mustafa R. Bashir, Brian M. Dale, Elmar M. Merkle, Caecilia S. Reiner, Kamil F. Faridi, and Rajan T. Gupta. “Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values..” Ajr Am J Roentgenol 200, no. 3 (March 2013): W297–303. https://doi.org/10.2214/AJR.12.9080.
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    • Gupta, Rajan T. “Evaluation of the biliary tree and gallbladder with hepatocellular MR contrast agents..” Curr Probl Diagn Radiol 42, no. 2 (March 2013): 67–76. https://doi.org/10.1067/j.cpradiol.2012.08.004.
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    • Bashir, Mustafa R., Rajan T. Gupta, Matthew S. Davenport, Brian C. Allen, Tracy A. Jaffe, Lisa M. Ho, Daniel T. Boll, and Elmar M. Merkle. “Hepatocellular carcinoma in a North American population: does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis?.” J Magn Reson Imaging 37, no. 2 (February 2013): 398–406. https://doi.org/10.1002/jmri.23818.
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    • Lee Langman, Eun, Barbara S. Hertzberg, Brita K. Boyd, and Rajan T. Gupta. “Dichorionic, diamnionic twin pregnancy discordant for anencephaly: Report of two cases and literature review..” Radiol Case Rep 8, no. 2 (2013). https://doi.org/10.2484/rcr.v8i2.843.
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    • Davis, E. E., A. S. Lagoo, and R. T. Gupta. “Nodular regenerative hyperplasia in the setting of Budd-Chiari syndrome: Application of MR with hepatobiliary contrast agents and histologic confirmation.” Journal of Surgical Radiology 3, no. 4 (December 21, 2012): 224–29.
    • Gupta, Rajan T., Daniele Marin, Daniel T. Boll, Daniela B. Husarik, Drew E. Davis, Sebastian Feuerlein, and Elmar M. Merkle. “Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium..” Eur J Radiol 81, no. 10 (October 2012): 2457–62. https://doi.org/10.1016/j.ejrad.2011.10.014.
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    • Bashir, Mustafa R., Brian M. Dale, Rajan T. Gupta, Jeffrey J. Horvath, Daniel T. Boll, and Elmar M. Merkle. “Gradient shimming during magnetic resonance imaging of the liver: comparison of a standard protocol versus a novel reduced protocol..” Invest Radiol 47, no. 9 (September 2012): 524–29. https://doi.org/10.1097/RLI.0b013e31825a8e5b.
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    • Feuerlein, Sebastian, Rajan T. Gupta, Daniel T. Boll, and Elmar M. Merkle. “Hepatocellular MR contrast agents: enhancement characteristics of liver parenchyma and portal vein after administration of gadoxetic acid in comparison to gadobenate dimeglumine..” Eur J Radiol 81, no. 9 (September 2012): 2037–41. https://doi.org/10.1016/j.ejrad.2011.06.014.
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    • Gupta, Rajan T., Christine M. Iseman, John R. Leyendecker, Inna Shyknevsky, Elmar M. Merkle, and Bachir Taouli. “Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium..” Ajr Am J Roentgenol 199, no. 1 (July 2012): 35–43. https://doi.org/10.2214/AJR.11.7757.
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    • Krishnan, Pranay, Rajan T. Gupta, Daniel T. Boll, Christopher M. Brady, Daniela B. Husarik, and Elmar M. Merkle. “Functional evaluation of cystic duct patency with Gd-EOB-DTPA MR imaging: an alternative to hepatobiliary scintigraphy for diagnosis of acute cholecystitis?.” Abdom Imaging 37, no. 3 (June 2012): 457–64. https://doi.org/10.1007/s00261-011-9785-y.
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    • Bashir, Mustafa R., and Rajan T. Gupta. “MDCT evaluation of the pancreas: nuts and bolts..” Radiologic Clinics of North America 50, no. 3 (May 2012): 365–77. https://doi.org/10.1016/j.rcl.2012.03.012.
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    • Ho, Lisa M., Daniele Marin, Amy M. Neville, Huiman X. Barnhart, Rajan T. Gupta, Erik K. Paulson, and Daniel T. Boll. “Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?.” Ajr Am J Roentgenol 198, no. 4 (April 2012): 840–45. https://doi.org/10.2214/AJR.11.7316.
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    • Bashir, Mustafa R., Daniela B. Husarik, Tim J. Ziemlewicz, Rajan T. Gupta, Daniel T. Boll, and Elmar M. Merkle. “Liver MRI in the hepatocyte phase with gadolinium-EOB-DTPA: does increasing the flip angle improve conspicuity and detection rate of hypointense lesions?.” J Magn Reson Imaging 35, no. 3 (March 2012): 611–16. https://doi.org/10.1002/jmri.22850.
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    • Husarik, Daniela B., Rajan T. Gupta, Kristina I. Ringe, Daniel T. Boll, and Elmar M. Merkle. “Contrast enhanced liver MRI in patients with primary sclerosing cholangitis: inverse appearance of focal confluent fibrosis on delayed phase MR images with hepatocyte specific versus extracellular gadolinium based contrast agents..” Acad Radiol 18, no. 12 (December 2011): 1549–54. https://doi.org/10.1016/j.acra.2011.08.007.
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    • Lungren, Matthew P., Jared D. Christensen, R Edward Coleman, and Rajan T. Gupta. “PET appearance of tuberculous empyema necessitans..” Clin Nucl Med 36, no. 10 (October 2011): 939–41. https://doi.org/10.1097/RLU.0b013e3182291bfd.
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    • Ringe, Kristina I., Daniela B. Husarik, Rajan T. Gupta, Daniel T. Boll, and Elmar M. Merkle. “Hepatobiliary transit times of gadoxetate disodium (Primovist®) for protocol optimization of comprehensive MR imaging of the biliary system--what is normal?.” European Journal of Radiology 79, no. 2 (August 2011): 201–5. https://doi.org/10.1016/j.ejrad.2010.03.008.
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    • Miller, Chad M., Rajan T. Gupta, Erik K. Paulson, Amy M. Neville, Mustafa R. Bashir, Elmar M. Merkle, and Daniel T. Boll. “Effect of organ enhancement and habitus on estimation of unenhanced attenuation at contrast-enhanced dual-energy MDCT: concepts for individualized and organ-specific spectral iodine subtraction strategies..” Ajr Am J Roentgenol 196, no. 5 (May 2011): W558–64. https://doi.org/10.2214/AJR.10.4858.
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    • Neville, Amy M., Rajan T. Gupta, Chad M. Miller, Elmar M. Merkle, Erik K. Paulson, and Daniel T. Boll. “Detection of renal lesion enhancement with dual-energy multidetector CT..” Radiology 259, no. 1 (April 2011): 173–83. https://doi.org/10.1148/radiol.10101170.
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    • Feuerlein, Sebastian, Daniel T. Boll, Rajan T. Gupta, Kristina I. Ringe, Daniele Marin, and Elmar M. Merkle. “Gadoxetate disodium-enhanced hepatic MRI: dose-dependent contrast dynamics of hepatic parenchyma and portal vein..” Ajr Am J Roentgenol 196, no. 1 (January 2011): W18–24. https://doi.org/10.2214/AJR.10.4387.
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    • Paxton, B. E., C. Y. Kim, M. J. Miller, and R. T. Gupta. “Successful endovascular management of a transected horseshoe kidney.” Journal of Surgical Radiology 2, no. 1 (January 1, 2011): 80–85.
    • Gupta, Rajan T., Christopher M. Brady, Joachim Lotz, Daniel T. Boll, and Elmar M. Merkle. “Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents..” Ajr Am J Roentgenol 195, no. 2 (August 2010): 405–13. https://doi.org/10.2214/AJR.09.3641.
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    • Coursey, Courtney A., Rendon C. Nelson, Daniel T. Boll, Erik K. Paulson, Lisa M. Ho, Amy M. Neville, Daniele Marin, Rajan T. Gupta, and Sebastian T. Schindera. “Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging?.” Radiographics 30, no. 4 (July 2010): 1037–55. https://doi.org/10.1148/rg.304095175.
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    • Gupta, Rajan T., Lisa M. Ho, Daniele Marin, Daniel T. Boll, Huiman X. Barnhart, and Rendon C. Nelson. “Dual-energy CT for characterization of adrenal nodules: initial experience..” Ajr Am J Roentgenol 194, no. 6 (June 2010): 1479–83. https://doi.org/10.2214/AJR.09.3476.
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    • Ringe, Kristina I., Rajan T. Gupta, Christopher M. Brady, Christopher M. Massey, Andreas Hahn, Michael Galanski, Elmar M. Merkle, and Joachim Lotz. “Respiratory-triggered three-dimensional T2-weighted MR cholangiography after injection of gadoxetate disodium: is it still reliable?.” Radiology 255, no. 2 (May 2010): 451–58. https://doi.org/10.1148/radiol.10091130.
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    • Gupta, Rajan T., Rajesh K. Kakarla, Kevin J. Kirshenbaum, and Victor F. Tapson. “D-dimers and efficacy of clinical risk estimation algorithms: sensitivity in evaluation of acute pulmonary embolism..” Ajr Am J Roentgenol 193, no. 2 (August 2009): 425–30. https://doi.org/10.2214/AJR.08.2186.
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    • Gupta, Rajan T., Rakhee P. Wadhwa, Thomas J. Learch, and Steven M. Herwick. “Lisfranc injury: imaging findings for this important but often-missed diagnosis..” Curr Probl Diagn Radiol 37, no. 3 (May 2008): 115–26. https://doi.org/10.1067/j.cpradiol.2007.08.012.
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    • Gupta, Rajan T., Stephen Vankoski, Robert A. Novak, and Luciano S. Dias. “Trunk kinematics and the influence on valgus knee stress in persons with high sacral level myelomeningocele..” J Pediatr Orthop 25, no. 1 (January 2005): 89–94. https://doi.org/10.1097/00004694-200501000-00020.
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  • Book Sections

    • Gupta, R. T., and D. Marin. “Multimodality approach to detection and characterization of hepatic hemangiomas.” In Abdomen and Thoracic Imaging: An Engineering and Clinical Perspective, 123–44, 2014. https://doi.org/10.1007/978-1-4614-8498-1_5.
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  • Conference Papers

    • Harshman, Lauren Christine, Maneka Puligandla, Naomi B. Haas, Mohamad Allaf, Charles G. Drake, David F. McDermott, Sabina Signoretti, et al. “PROSPER: A phase III randomized study comparing perioperative nivolumab (nivo) versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN 8143)..” In Journal of Clinical Oncology, 37:TPS4597–TPS4597. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.tps4597.
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    • Labriola, Matthew, Jason Zhu, Sachica Cheris, Xin Liu, Kathryn Perkinson, Zuowei Su, Shannon McCall, et al. “Concordance between PD-L1 assays for metastatic renal cell carcinoma (mRCC) and metastatic urothelial carcinoma (mUC)..” In Journal of Clinical Oncology, 37:e14259–e14259. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.e14259.
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    • Zhu, Jason, Sarabjot Pabla, Matthew Labriola, Rajan T. Gupta, Shannon McCall, Daniel J. George, Devin Dressman, et al. “Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor (ICI) response in metastatic renal cell carcinoma (mRCC)..” In Journal of Clinical Oncology, 37:2595–2595. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.2595.
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    • Zhu, Jason, Sarabjot Pabla, Matthew Labriola, Rajan T. Gupta, Shannon McCall, Daniel J. George, Devin Dressman, et al. “Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor (ICI) response in metastatic renal cell carcinoma (mRCC)..” In Journal of Clinical Oncology, 37:63–63. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.8_suppl.63.
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    • Barton, Gregory John, Jeanette Wang, Andrew Chang, Wei Phin Tan, Joseph J. Fantony, Paul E. Wischmeyer, Rajan T. Gupta, and Brant Allen Inman. “Sarcopenia in bladder cancer patients is an unmodifiable outcomes predictor..” In Journal of Clinical Oncology, 37:480–480. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.480.
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    • Harshman, Lauren Christine, Maneka Puligandla, Naomi B. Haas, Mohamad Allaf, Charles G. Drake, David F. McDermott, Sabina Signoretti, et al. “PROSPER: A phase III randomized study comparing perioperative nivolumab (nivo) versus observation in patients with localized renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN 8143)..” In Journal of Clinical Oncology, 37:TPS684–TPS684. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.tps684.
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    • Zhu, Jason, Sarabjot Pabla, Matthew Labriola, Rajan T. Gupta, Shannon McCall, Daniel J. George, Devin Dressman, et al. “Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor (ICI) response in metastatic renal cell carcinoma (mRCC)..” In Journal of Clinical Oncology, 37:607–607. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.607.
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    • Harrison, M. R., P. G. Davis, M. G. Khouri, R. T. Gupta, A. J. Armstrong, M. A. McNamara, T. Zhang, et al. “EXTEND: Safety and efficacy of exercise training in men receiving enzalutamide (ENZ) in combination with conventional androgen deprivation therapy (ADT) for hormone naive prostate cancer (HSPC).” In Annals of Oncology, Vol. 29. OXFORD UNIV PRESS, 2018.
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    • Harshman, Lauren Christine, Maneka Puligandla, Naomi B. Haas, Mohamad Allaf, Charles G. Drake, David F. McDermott, Sabina Signoretti, et al. “A phase III randomized study comparing perioperative nivolumab vs. observation in patients with localized renal cell carcinoma undergoing nephrectomy (PROSPER RCC)..” In Journal of Clinical Oncology, 36:TPS710–TPS710. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.tps710.
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    • Cody Morris, D., D. Y. Chan, M. L. Palmeri, T. J. Glass, M. M. McCormick, K. Jack Tay, T. J. Polascik, R. T. Gupta, and K. R. Nightingale. “Correlation Between 3D ARFI and Quantitative Imaging Metrics from SWEI and Multi-Parametric MRI in Vivo in Normal and Cancerous Prostate Tissue.” In Ieee International Ultrasonics Symposium, Ius, Vol. 2018-January, 2018. https://doi.org/10.1109/ULTSYM.2018.8579729.
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    • Harshman, Lauren Christine, Maneka Puligandla, Naomi B. Haas, Mohamad Allaf, Charles G. Drake, David F. McDermott, Sabina Signoretti, et al. “A phase III randomized study comparing perioperative nivolumab vs. observation in patients with localized renal cell carcinoma undergoing nephrectomy (PROSPER RCC)..” In Journal of Clinical Oncology, 35:TPS4596–TPS4596. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.tps4596.
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    • Humeniuk, Michael Sandon, Rajan T. Gupta, Megan Ann McNamara, Sundhar Ramalingam, Michael Roger Harrison, Daniel J. George, Yuan Wu, Patrick Healy, and Andrew J. Armstrong. “Association of neuroendocrine phenotype with platinum chemotherapy outcomes in men with metastatic prostate cancer..” In Journal of Clinical Oncology, 35:e16532–e16532. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.e16532.
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    • Palmeri, M., T. Glass, R. Gupta, M. McCormick, A. Brown, T. Polascik, S. Rosenzweig, A. Buck, and K. Nightingale. “Comparison between 3D ARFI imaging and mpMRI in detecting clinically-significant prostate cancer lesions.” In Ieee International Ultrasonics Symposium, Ius, Vol. 2016-November, 2016. https://doi.org/10.1109/ULTSYM.2016.7728618.
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    • Reiner, C., R. Gupta, M. Bashir, N. Walle, H. Nazeer, and E. Merkle. “Hepatobiliary-Specific MR Contrast Agents: Is There Added Value of T1-Weighted MR Cholangiography in the Assessment of Biliary Ductal Obstruction?.” In American Journal of Roentgenology, Vol. 198. AMER ROENTGEN RAY SOC, 2012.
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    • Hsu, C. M. L., T. J. Polascik, M. S. Davenport, C. Kauffman, R. T. Gupta, E. Kulbacki, J. Madden, S. L. Lipman, M. L. Palmeri, and K. R. Nightingale. “Methodology to register prostate B-mode and ARFI images to MR and histology.” In Ieee International Ultrasonics Symposium, Ius, 1866–69, 2011. https://doi.org/10.1109/ULTSYM.2011.0466.
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    • Feuerlein, S., D. Boll, R. Gupta, D. Marin, and E. Merkle. “Gd-EOB-DTPA-enhanced Hepatic MRI: Dose-Dependent Contrast-Dynamics of Hepatic Parenchyma and Portal Vein.” In American Journal of Roentgenology, Vol. 194. AMER ROENTGEN RAY SOC, 2010.
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    • Marin, D., R. Gupta, D. Boll, S. Feuerlein, D. Husarik, and E. Merkle. “Hepatic Hemangioma: Enhancement Pattern at Gadobenate Dimeglumine- and Gadoxetate Disodium-Enhanced 3T MRI.” In American Journal of Roentgenology, Vol. 194. AMER ROENTGEN RAY SOC, 2010.
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    • Gupta, R., L. Ho, D. Marin, D. Boll, and R. Nelson. “Characterization of Adrenal Masses: Can Dual Energy CT Improve Differentiation Between Adenomas and Metastases?.” In American Journal of Roentgenology, Vol. 192. AMER ROENTGEN RAY SOC, 2009.
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