Scholars@Duke
Rajan Tilak Gupta

Rajan Tilak Gupta

Professor of Radiology
Radiology, Abdominal Imaging
rajan.gupta@duke.edu
Department of Radiology, BOX_3808 Med Ctr, Durham, NC 27710

Featured Works

Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values.

Journal article AJR Am J Roentgenol · March 2013 Featured Work OBJECTIVE: The purpose of this study was to determine the effects of age and fat content on quantitative dynamic contrast-enhanced MRI (DCE-MRI) parameters in the bone marrow of the lumbar spine and pelvis. The interreader reproducibility of this technique ... Full text Link to item Cite

Hepatocellular carcinoma in a North American population: does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis?

Journal article J Magn Reson Imaging · February 2013 Featured Work PURPOSE: To evaluate the value of hepatobiliary phase imaging for detection and characterization of hepatocellular carcinoma (HCC) in liver MRI with Gd-EOB-DTPA, in a North American population. MATERIALS AND METHODS: One hundred MRI examinations performed ... Full text Link to item Cite

Evaluation of the biliary tree and gallbladder with hepatocellular MR contrast agents.

Journal article Curr Probl Diagn Radiol · 2013 Featured Work Newer hepatobiliary magnetic resonance (MR) contrast agents allow the ability to combine the anatomical information from T2-weighted magnetic resonance cholangiopancreatography with functional information derived from contrast-enhanced T1-weighted magnetic ... Full text Link to item Cite

Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium.

Journal article Eur J Radiol · October 2012 Featured Work PURPOSE: To compare intraindividual differences in enhancement pattern of hepatic hemangiomas between gadobenate dimeglumine (Gd-BOPTA) and gadoxetate disodium (Gd-EOB-DTPA)-enhanced 3T MR imaging. MATERIALS AND METHODS: This is a HIPAA-compliant, IRB-appr ... Full text Link to item Cite

Hepatocellular MR contrast agents: enhancement characteristics of liver parenchyma and portal vein after administration of gadoxetic acid in comparison to gadobenate dimeglumine.

Journal article Eur J Radiol · September 2012 Featured Work PURPOSE: To investigate the enhancement characteristics of liver parenchyma and portal vein as well as the portal vein-to liver contrast in Gd-EOB-DTPA- and Gd-BOPTA-enhanced abdominal MRI. MATERIALS AND METHODS: The local institutional review board approv ... Full text Link to item Cite

Gradient shimming during magnetic resonance imaging of the liver: comparison of a standard protocol versus a novel reduced protocol.

Journal article Invest Radiol · September 2012 Featured Work PURPOSE: The aim of this study was to examine the effect of minimizing prescan adjustments on table time and image quality in magnetic resonance imaging (MRI) of the liver. MATERIALS AND METHODS: This prospective Health Insurance Portability and Accountabi ... Full text Link to item Cite

Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium.

Journal article AJR Am J Roentgenol · July 2012 Featured Work OBJECTIVE: The purpose of this article is to report the results from a multicenter retrospective MRI study comparing gadobenate dimeglumine and gadoxetate disodium for diagnosis of hepatic focal nodular hyperplasia (FNH). MATERIALS AND METHODS: Thirty pati ... Full text Link to item Cite

Functional evaluation of cystic duct patency with Gd-EOB-DTPA MR imaging: an alternative to hepatobiliary scintigraphy for diagnosis of acute cholecystitis?

Journal article Abdom Imaging · June 2012 Featured Work PURPOSE: To determine if MR cholangiography with Gd-EOB-DTPA can be used to assess cystic duct patency and to establish normal time range for reflux of contrast material into the cystic duct/gallbladder. MATERIALS AND METHODS: This retrospective study is H ... Full text Link to item Cite

MDCT evaluation of the pancreas: nuts and bolts.

Journal article Radiol Clin North Am · May 2012 Featured Work Multidetector-row CT (MDCT) imaging of the pancreas has important roles in diagnosis, staging, and treatment monitoring of a vast array of pancreatic diseases. Optimizing MDCT protocols not only requires an understanding of expected pathologies but also mu ... Full text Link to item Cite

Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?

Journal article AJR Am J Roentgenol · April 2012 Featured Work OBJECTIVE: The purpose of our study was to investigate whether virtual unenhanced adrenal nodule attenuation values can replace true noncontrast attenuation values. MATERIALS AND METHODS: Twenty-three incidentally discovered adrenal nodules (19 adenomas an ... Full text Link to item Cite

Liver MRI in the hepatocyte phase with gadolinium-EOB-DTPA: does increasing the flip angle improve conspicuity and detection rate of hypointense lesions?

Journal article J Magn Reson Imaging · March 2012 Featured Work PURPOSE: To compare conspicuity and detection rate of hypointense lesions on T1-weighted (T1w) gradient echo (GRE) sequences with low and high flip angles (FA) in hepatocyte phase magnetic resonance imaging (MRI) using gadoxetate disodium. MATERIALS AND ME ... Full text Link to item Cite

Contrast enhanced liver MRI in patients with primary sclerosing cholangitis: inverse appearance of focal confluent fibrosis on delayed phase MR images with hepatocyte specific versus extracellular gadolinium based contrast agents.

Journal article Acad Radiol · December 2011 Featured Work RATIONALE AND OBJECTIVES: To assess the enhancement pattern of focal confluent fibrosis (FCF) on contrast-enhanced hepatic magnetic resonance imaging (MRI) using hepatocyte-specific (Gd-EOB-DTPA) and extracellular (ECA) gadolinium-based contrast agents in ... Full text Link to item Cite

PET appearance of tuberculous empyema necessitans.

Journal article Clin Nucl Med · October 2011 Featured Work Full text Link to item Cite

Hepatobiliary transit times of gadoxetate disodium (Primovist®) for protocol optimization of comprehensive MR imaging of the biliary system--what is normal?

Journal article Eur J Radiol · August 2011 Featured Work OBJECTIVE: The purpose of this study was to determine transit times for excretion of Gd-EOB-DTPA into different segments of the hepatobiliary system in patients with normal liver function. METHODS: This retrospective study was IRB approved with a waiver of ... Full text Link to item Cite

Effect of organ enhancement and habitus on estimation of unenhanced attenuation at contrast-enhanced dual-energy MDCT: concepts for individualized and organ-specific spectral iodine subtraction strategies.

Journal article AJR Am J Roentgenol · May 2011 Featured Work OBJECTIVE: The purpose of this study was to assess whether habitus and organ enhancement influence iodine subtraction and should be incorporated into spectral subtraction algorithms. SUBJECTS AND METHODS: This study included 171 patients. In the unenhanced ... Full text Link to item Cite

Detection of renal lesion enhancement with dual-energy multidetector CT.

Journal article Radiology · April 2011 Featured Work PURPOSE: To determine whether dual-energy multidetector CT enables detection of renal lesion enhancement by using calculated nonenhanced images with spectral-based extraction in a non-body weight-restricted patient population. MATERIALS AND METHODS: Betwee ... Full text Link to item Cite

Gadoxetate disodium-enhanced hepatic MRI: dose-dependent contrast dynamics of hepatic parenchyma and portal vein.

Journal article AJR Am J Roentgenol · January 2011 Featured Work OBJECTIVE: The purpose of this study was to investigate the relative enhancement characteristics of the hepatic parenchyma and portal vein during gadoxetate disodium-enhanced abdominal MRI and to assess whether contrast between the portal vein and the hepa ... Full text Link to item Cite

Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents.

Journal article AJR Am J Roentgenol · August 2010 Featured Work OBJECTIVE: The objective of our study was to illustrate how the properties of hepatocyte-specific MR contrast agents can be used in the dynamic evaluation of the biliary system. CONCLUSION: Because of their dual route of excretion through the kidneys and t ... Full text Link to item Cite

Dual-energy CT for characterization of adrenal nodules: initial experience.

Journal article AJR Am J Roentgenol · June 2010 Featured Work OBJECTIVE: The purpose of this study was to determine whether use of dual-energy technique can improve the diagnostic performance of CT in the differential diagnosis of adrenal adenomas and metastatic lesions. SUBJECTS AND METHODS: Thirty-one adrenal nodul ... Full text Link to item Cite

Respiratory-triggered three-dimensional T2-weighted MR cholangiography after injection of gadoxetate disodium: is it still reliable?

Journal article Radiology · May 2010 Featured Work PURPOSE: To test the null hypothesis that there is no quantitative or qualitative difference between respiratory-triggered three-dimensional (3D) T2-weighted magnetic resonance (MR) cholangiography performed before or after administration of gadoxetate dis ... Full text Link to item Cite

Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging?

Journal article Radiographics · 2010 Featured Work Dual-energy CT provides information about how substances behave at different energies, the ability to generate virtual unenhanced datasets, and improved detection of iodine-containing substances on low-energy images. Knowing how a substance behaves at two ... Full text Link to item Cite

D-dimers and efficacy of clinical risk estimation algorithms: sensitivity in evaluation of acute pulmonary embolism.

Journal article AJR Am J Roentgenol · August 2009 Featured Work OBJECTIVE: The goal of this study was to test the efficacy of clinical risk algorithms and a quantitative immunoturbidimetric D-dimer assay in the evaluation of patients undergoing pulmonary CT angiography for suspected acute pulmonary embolism. SUBJECTS A ... Full text Link to item Cite

Lisfranc injury: imaging findings for this important but often-missed diagnosis.

Journal article Curr Probl Diagn Radiol · 2008 Featured Work The Lisfranc injury is a popular topic in the radiology, orthopedic surgery, and emergency medicine literature, primarily due to the subtleties of the radiographic findings and potentially dire consequences of missed diagnoses. The purpose of this article ... Full text Link to item Cite