Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • residency, Psychiatry And Behavioral Sciences, Duke University School of Medicine 2008 - 2012
  • M.D., University of Wisconsin - Madison 2008
  • Ph.D., University of Wisconsin - Madison 2006
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2017 - 2021
  • Consulting Associate in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2015 - 2016
  • Consulting Associate in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology, Psychiatry & Behavioral Sciences 2013 - 2015
  • Consulting Associate in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2012 - 2013
• Research
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  External Relationships

  • medlink
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Jakel, Rebekah J. “Posttraumatic Stress Disorder in the Elderly.” Clin Geriatr Med 36, no. 2 (May 2020): 353–63. https://doi.org/10.1016/j.cger.2019.11.013.
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    • Jakel, Rebekah J. “Posttraumatic Stress Disorder in the Elderly.” Psychiatr Clin North Am 41, no. 1 (March 2018): 165–75. https://doi.org/10.1016/j.psc.2017.10.013.
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    • Jakel, R. J., and M. A. Stacy. “Psychosis and Parkinson's disease.” Advances in Biological Psychiatry 27 (December 4, 2012): 53–60. https://doi.org/10.1159/000331526.
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    • Muzyk, Andrew J., Rebekah J. Jakel, and Xavier Preud’homme. “Serotonin syndrome after a massive overdose of controlled-release paroxetine.” Psychosomatics 51, no. 5 (2010): 437–42. https://doi.org/10.1176/appi.psy.51.5.437.
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    • Johnson, Jeffrey A., Delinda A. Johnson, Andrew D. Kraft, Marcus J. Calkins, Rebekah J. Jakel, Marcelo R. Vargas, and Pei-Chun Chen. “The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration.” Ann N Y Acad Sci 1147 (December 2008): 61–69. https://doi.org/10.1196/annals.1427.036.
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    • Johnson, J. A., D. A. Johnson, J. M. Lee, J. Li, A. D. Kraft, M. J. Calkins, and R. J. Jakel. “The Nrf2-ARE pathway: A potential therapeutic target for neurodegenerative diseases.” International Congress Series 1302 (June 1, 2007): 143–53. https://doi.org/10.1016/j.ics.2006.10.026.
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    • Jakel, Rebekah J., Jessica A. Townsend, Andrew D. Kraft, and Jeffrey A. Johnson. “Nrf2-mediated protection against 6-hydroxydopamine.” Brain Res 1144 (May 4, 2007): 192–201. https://doi.org/10.1016/j.brainres.2007.01.131.
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    • Jakel, Rebekah J., Jonathan T. Kern, Delinda A. Johnson, and Jeffrey A. Johnson. “Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro.” Toxicol Sci 87, no. 1 (September 2005): 176–86. https://doi.org/10.1093/toxsci/kfi241.
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    • Lee, Jong-Min, Jiang Li, Delinda A. Johnson, Thor D. Stein, Andrew D. Kraft, Marcus J. Calkins, Rebekah J. Jakel, and Jeffrey A. Johnson. “Nrf2, a multi-organ protector?” Faseb J 19, no. 9 (July 2005): 1061–66. https://doi.org/10.1096/fj.04-2591hyp.
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    • Calkins, Marcus J., Rebekah J. Jakel, Delinda A. Johnson, Kaimin Chan, Yuet Wai Kan, and Jeffrey A. Johnson. “Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription.” Proc Natl Acad Sci U S A 102, no. 1 (January 4, 2005): 244–49. https://doi.org/10.1073/pnas.0408487101.
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    • McBride, Jodi L., Soshana P. Behrstock, Er-Yun Chen, Rebekah J. Jakel, Irwin Siegel, Clive N. Svendsen, and Jeffrey H. Kordower. “Human neural stem cell transplants improve motor function in a rat model of Huntington's disease.” J Comp Neurol 475, no. 2 (July 19, 2004): 211–19. https://doi.org/10.1002/cne.20176.
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    • Jakel, Rebekah J., Bernard L. Schneider, and Clive N. Svendsen. “Using human neural stem cells to model neurological disease.” Nat Rev Genet 5, no. 2 (February 2004): 136–44. https://doi.org/10.1038/nrg1268.
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    • Maragos, W. F., R. Jakel, D. Chesnut, C. B. Pocernich, D. A. Butterfield, D. St Clair, and W. A. Cass. “Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase.” Brain Res 878, no. 1–2 (September 29, 2000): 218–22. https://doi.org/10.1016/s0006-8993(00)02707-4.
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    • Jakel, R. J., and W. F. Maragos. “Neuronal cell death in Huntington's disease: a potential role for dopamine.” Trends Neurosci 23, no. 6 (June 2000): 239–45. https://doi.org/10.1016/s0166-2236(00)01568-x.
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    • Maragos, W. F., P. A. Tillman, M. D. Chesnut, and R. J. Jakel. “Clorgyline and deprenyl attenuate striatal malonate and 3-nitropropionic acid lesions.” Brain Res 834, no. 1–2 (July 10, 1999): 168–72. https://doi.org/10.1016/s0006-8993(99)01487-0.
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    • Kruman, I. I., A. Nath, W. F. Maragos, S. L. Chan, M. Jones, V. M. Rangnekar, R. J. Jakel, and M. P. Mattson. “Evidence that Par-4 participates in the pathogenesis of HIV encephalitis.” Am J Pathol 155, no. 1 (July 1999): 39–46. https://doi.org/10.1016/S0002-9440(10)65096-1.
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    • Maragos, W. F., R. J. Jakel, M. D. Chesnut, J. W. Geddes, and L. P. Dwoskin. “Does dopamine contribute to striatal damage caused by impaired mitochondrial function?” Ann N Y Acad Sci 893 (1999): 345–49. https://doi.org/10.1111/j.1749-6632.1999.tb07851.x.
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    • Maragos, W. F., R. J. Jakel, Z. Pang, and J. W. Geddes. “6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions.” Exp Neurol 154, no. 2 (December 1998): 637–44. https://doi.org/10.1006/exnr.1998.6918.
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  • Book Sections

    • Jakel, R. J., and M. A. Stacy. “Psychosis and Parkinson's disease.” In Psychiatry of Parkinson’s Disease, 27:53–60, 2012. https://doi.org/10.1159/000331526.
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    • Burton, N. C., D. A. Johnson, J. M. Lee, A. D. Kraft, M. J. Calkins, R. J. Jakel, and J. A. Johnson. “Neurotoxicant-Induced Oxidative Events and Antioxidative Interventions in the Central Nervous System.” In Comprehensive Toxicology, Second Edition, 13:59–69, 2010. https://doi.org/10.1016/B978-0-08-046884-6.01305-1.
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