Scholars@Duke
Richard B. Fair

Richard B. Fair

Lord-Chandran Distinguished Professor Emeritus of Engineering
Pierre R. Lamond Department of Electrical and Computer Engineering
Box 90291, Durham, NC 27708-0291
3519 CIEMAS, Dept. of Electrical and Computer Engrg., Durham, NC 27708
Office hours MWF 1:30-3:00pm  

Scholarly Works - Conferences

Enhanced fluorescent detection of nucleosomes using functionalized magnetic beads on a digital microfluidic device

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2022 Epigenetics, the study of inheritable mechanisms that regulate gene expression, has clinical ramifications from cancer to autoimmune disorders to psychiatric pathologies. The main tool to study epigenetics is chromatin immunoprecipitation (ChIP), which pro ... Full text Cite

Fluorescent detection of nucleosomes using functionalized magnetic beads on a digital microfluidic device

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2021 Epigenetics, the study of inheritable mechanisms that regulate gene expression, has clinical ramifications from cancer to autoimmune disorders to psychiatric pathologies. The main tool to study epigenetics is chromatin immunoprecipitation (ChIP), which pro ... Full text Cite

ENHANCED BIOMOLECULAR BINDING TO BEADS ON A DIGITAL MICROFLUIDIC DEVICE

Conference Microtas 2021 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences · January 1, 2021 Biomolecular assays typically require large reagent volumes, long processing times and provide low throughput analysis. To overcome some of these limitations, we have developed devices to enhance binding efficiencies between antibodies and magnetic beads i ... Cite

Adaptive droplet routing in digital microfluidic biochips using deep reinforcement learning

Conference 37th International Conference on Machine Learning Icml 2020 · January 1, 2020 We present and investigate a novel application domain for deep reinforcement learning (RL): droplet routing on digital microfluidic biochips (DMFBs). A DMFB, composed of a twodimensional electrode array, manipulates discrete fluid droplets to automatically ... Cite

Adaptive Droplet Routing in Digital Microfluidic Biochips Using Deep Reinforcement Learning

Conference Proceedings of Machine Learning Research · January 1, 2020 We present and investigate a novel application domain for deep reinforcement learning (RL): droplet routing on digital microfluidic biochips (DMFBs). A DMFB, composed of a twodimensional electrode array, manipulates discrete fluid droplets to automatically ... Cite

Experimental demonstration of error recovery in an integrated cyberphysical digital-microfluidic platform

Conference IEEE Biomedical Circuits and Systems Conference Engineering for Healthy Minds and Able Bodies Biocas 2015 Proceedings · December 4, 2015 Digital (droplet-based) microfluidics enables the integration of fluid-handling operations and reaction-outcome detection. Despite these benefits, defects and erroneous fluidic operations continue to be major barriers to the adoption and deployment of thes ... Full text Cite

Intra-droplet magnetic bead manipulation integrated on a digital microfluidic chip

Conference 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2014 · January 1, 2014 This paper demonstrates a device which is capable of performing both magnetic molecular segregation within a droplet as well as droplet actuation. Segregation of magnetic beads is performed within a droplet while the droplet is dispensed and transported us ... Cite

Design and testing of an interpolating mixing architecture for electrowetting-based droplet-on-chip chemical dilution

Conference Transducers 2003 12th International Conference on Solid State Sensors Actuators and Microsystems Digest of Technical Papers · January 1, 2003 An on-chip dilution scheme for an electrowetting based microfluidic system is presented in this paper. The dilution scheme uses the mixing and splitting of two droplets of different concentrations to result in an intermediate concentration, as the fundamen ... Full text Cite

Micro/nano liter droplet formation and dispensing by capacitance metering and electrowetting actuation

Conference Proceedings of the IEEE Conference on Nanotechnology · January 1, 2002 In this work, a method is presented for dispensing droplets. The method exploits the built-in capacitance of an electrowetting device to meter the droplet volume and control the dispensing process dynamically. A fully automated droplet dispensing device is ... Full text Cite

Microfluidic electrowetting-based droplet mixing

Conference 2001 Microelectromechanical Systems Conference MEMS 2001 · January 1, 2002 We present a liquid droplet mixer to enable mixing of the samples and reagents for chemical and biological analysis in micro total analysis systems (μTAS). The droplets in the mixer are actuated based on electrowetting phenomenon. The actuator comprises of ... Full text Cite

Rapid thermal annealing issues in silicon processing

Conference TRANSIENT THERMAL PROCESSING TECHNIQUES IN ELECTRONIC MATERIALS · January 1, 1996 Link to item Cite

Boron diffusion in ultrathin silicon dioxide layers

Conference PHYSICS AND CHEMISTRY OF SIO(2) AND THE SI-SIO(2) INTERFACE-3, 1996 · January 1, 1996 Link to item Cite

Process simulation of dopant atom diffusion in SiO2

Conference PROCEEDINGS OF THE FOURTH INTERNATIONAL SYMPOSIUM ON PROCESS PHYSICS AND MODELING IN SEMICONDUCTOR TECHNOLOGY · January 1, 1996 Link to item Cite

TRANSIENT DIFFUSION IN SILICON - MODELS AND CURES

Conference JOURNAL OF ELECTRONIC MATERIALS · July 1, 1990 Link to item Cite

EFFECT OF STRAIN-INDUCED BAND-GAP NARROWING ON E-CENTRE CONCENTRATIONS IN Si.

Conference Institute of Physics Conference Series · January 1, 1979 A strain effect has been found to explain the anomalous reduction of phosphorus diffusivity in Si at surface concentrations greater than about 4 multiplied by 10**2**0 cm** minus **3. It is shown that band-gap narrowing results in reduce P diffusivity thro ... Cite