Current Appointments & Affiliations
Associate Professor of Medicine
·
2021 - Present
Medicine, Medical Oncology,
Medicine
Member of the Duke Cancer Institute
·
2021 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
SPOP Mutations in Veterans With Prostate Cancer and Outcomes With Doublet and Triplet Therapy in De Novo Metastatic Hormone Sensitive Prostate Cancer.
Journal Article Prostate · June 2026 BACKGROUND: Inactivating missense mutations in the tumor suppressor gene speckle-type pox virus and zinc finger protein (SPOP) occur in 5%-15% of men with prostate cancer (PC). SPOP mutations increase androgen receptor-mediated transcription and enhance se ... Full text Link to item CiteDocetaxel Rechallenge vs Cabazitaxel in Patients With Metastatic Castration-Resistant Prostate Cancer.
Journal Article JAMA Netw Open · January 2, 2026 IMPORTANCE: Docetaxel has been a standard treatment for metastatic castration-resistant prostate cancer (mCRPC) since 2004. Cabazitaxel, a related taxane, was approved in 2010 for patients with mCRPC who had been previously treated with docetaxel. The comp ... Full text Link to item CiteMagnetic Resonance Imaging or Confirmatory Biopsy for Patients With Prostate Cancer Receiving Active Surveillance.
Journal Article JAMA Oncol · January 1, 2026 Full text Link to item CiteRecent Grants
DoD: PCRP Clinical Consortium: Duke University Clinical Research Site
ResearchCollaborating Investigator · Awarded by Department of Defense · 2007 - 2026PARPi Response Evaluation for Clinical Impact and Scientific Innovation in Oncology: The PRECISION Registry
ResearchCo Investigator · Awarded by Thomas Jefferson University · 2022 - 2022Alternative splicing and epithelial-mesenchymal plasticity in prostate tumors
ResearchInvestigator · Awarded by National Institutes of Health · 2008 - 2014View All Grants
Education
Vanderbilt University ·
2005
M.D.