Richard S.E. Keefe | Scholars@Duke

Richard S.E. Keefe
Professor in Psychiatry and Behavioral Sciences

Schizophrenia, psychosis, cognition, pharmacologic treatment of cognitive impairment, sport psychology, functional imaging (PET, fMRI), frontal cortex, motor functions.

Current Appointments & Affiliations

Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Translational Neuroscience, Psychiatry & Behavioral Sciences 2007
Professor of Psychology and Neuroscience, Psychology and Neuroscience, Trinity College of Arts & Sciences 2011
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2008
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2016

Contact Information

4080 Hosp South, Durham, NC 27710
Box 3270 Med Ctr, Durham, NC 27710
richard.keefe@duke.edu (919) 684-4306

Background
Education, Training, & Certifications
- Ph.D., New York University 1990
Duke Appointment History
- Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Medical Psychology, Psychiatry & Behavioral Sciences 2005 - 2007
- Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Medical Psychology, Psychiatry & Behavioral Sciences 1997 - 2005
- Assistant Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Medical Psychology, Psychiatry & Behavioral Sciences 1995 - 1997
Recognition
In the News
- NOV 27, 2018
  
  Duke Faculty Plentiful On ‘Highly Cited’ List
- APR 24, 2014 The News & Observer
  
  Richard Keefe: Bruce Springsteen offers chance to recall impulsiveness of teen brains
Expertise
Global Scholarship
- Expertise
  - Singapore (Country)
- Research
  - Singapore (Country)
Research
Selected Grants
- BI 1289.32 Phase II Clinical Trial awarded by Boehringer Ingelheim Pharmaceuticals, Inc. 2017 - 2020
- Auditory Perception and Emotion Recognition in Young People at Risk for Psychosis awarded by National Institutes of Health 2016 - 2019
- FAST- MAS Phase 2A awarded by National Institutes of Health 2013 - 2017
- Specific Auditory Perception Impairment and Emotion Recognition in Schizophrenia awarded by National Institutes of Health 2014 - 2017
- FAST- MAS Administrative Task Year 3 awarded by National Institutes of Health 2014 - 2015
- IPA - Richard Keefe awarded by Durham Veterans Affairs Medical Center 2013 - 2014
- IPA - Richard Keefe awarded by Veterans Administration Medical Center 2012 - 2013
- IPA - Richard Keefe awarded by Veterans Administration Medical Center 2010 - 2011
- Neural Circuitry And Cognitive Function In Schizophrenia awarded by National Institutes of Health 1995 - 2001
- Neural Circuitry & Cognitive Function In Schizophrenia awarded by National Institutes of Health 1995 - 1999
- Neural Circuitry & Function In Schizophrenia awarded by National Institutes of Health 1995 - 1999
- Neural Corcuitry And Cognitive Function In Schizophrenia awarded by National Institutes of Health 1995 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Mahncke, HW, Kim, S-J, Rose, A, Stasio, C, Buckley, P, Caroff, S, Duncan, E, Yasmin, S, Jarskog, LF, Lamberti, JS, Nuechterlein, K, Strassnig, M, Velligan, D, Ventura, J, Walker, T, Stroup, TS, and Keefe, RSE. "Evaluation of a plasticity-based cognitive training program in schizophrenia: Results from the eCaesar trial." Schizophrenia Research (March 28, 2019). Full Text
  - Kraus, MS, Walker, TM, Jarskog, LF, Millet, RA, and Keefe, RSE. "Basic auditory processing deficits and their association with auditory emotion recognition in schizophrenia." Schizophrenia Research 204 (February 2019): 155-161. Full Text
  - Harvey, PD, Khan, A, Atkins, A, and Keefe, RS. "Virtual reality assessment of functional capacity in people with Schizophrenia: Associations with reduced emotional experience and prediction of functional outcomes." Psychiatry Research (January 15, 2019). Full Text
  - Wang, C, Lee, J, Ho, NF, Lim, JKW, Poh, JS, Rekhi, G, Krishnan, R, Keefe, RSE, Adcock, RA, Wood, SJ, Fornito, A, Chee, MWL, and Zhou, J. "Large-Scale Network Topology Reveals Heterogeneity in Individuals With at Risk Mental State for Psychosis: Findings From the Longitudinal Youth-at-Risk Study." Cerebral Cortex (New York, N.Y. : 1991) 28, no. 12 (December 2018): 4234-4243. Full Text
  - Keefe, RSE, and Pani, L. "Take This Cognitive Training Efficacy Bar Fight Outside (to a Regulatory Agency)." Biological Psychiatry. Cognitive Neuroscience and Neuroimaging 3, no. 11 (November 2018): 900-902. Full Text
  - Yang, Z, Lim, K, Lam, M, Keefe, R, and Lee, J. "Factor structure of the positive and negative syndrome scale (PANSS) in people at ultra high risk (UHR) for psychosis." Schizophrenia Research 201 (November 2018): 85-90. Full Text
  - Lam, M, Lee, J, Rapisarda, A, See, YM, Yang, Z, Lee, S-A, Abdul-Rashid, NA, Kraus, M, Subramaniam, M, Chong, S-A, and Keefe, RSE. "Longitudinal Cognitive Changes in Young Individuals at Ultrahigh Risk for Psychosis." Jama Psychiatry 75, no. 9 (September 2018): 929-939. Full Text
  - Xavier, RM, Dungan, JR, Keefe, RSE, and Vorderstrasse, A. "Polygenic signal for symptom dimensions and cognitive performance in patients with chronic schizophrenia." Schizophrenia Research: Cognition 12 (June 2018): 11-19. Full Text
  - Blokland, GAM, Del Re, EC, Mesholam-Gately, RI, Jovicich, J, Trampush, JW, Keshavan, MS, DeLisi, LE, Walters, JTR, Turner, JA, Malhotra, AK, Lencz, T, Shenton, ME, Voineskos, AN, Rujescu, D, Giegling, I, Kahn, RS, Roffman, JL, Holt, DJ, Ehrlich, S, Kikinis, Z, Dazzan, P, Murray, RM, Di Forti, M, Lee, J, Sim, K, Lam, M, Wolthusen, RPF, de Zwarte, SMC, Walton, E, Cosgrove, D, Kelly, S, Maleki, N, Osiecki, L, Picchioni, MM, Bramon, E, Russo, M, David, AS, Mondelli, V, Reinders, AATS, Falcone, MA, Hartmann, AM, Konte, B, Morris, DW, Gill, M, Corvin, AP, Cahn, W, Ho, NF, Liu, JJ, Keefe, RSE, Gollub, RL, Manoach, DS, Calhoun, VD, Schulz, SC, Sponheim, SR, Goff, DC, Buka, SL, Cherkerzian, S, Thermenos, HW, Kubicki, M, Nestor, PG, Dickie, EW, Vassos, E, Ciufolini, S, Reis Marques, T, Crossley, NA, Purcell, SM, Smoller, JW, van Haren, NEM, Toulopoulou, T, Donohoe, G, Goldstein, JM, Seidman, LJ, McCarley, RW, and Petryshen, TL. "The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project." Schizophrenia Research 195 (May 2018): 306-317. Full Text
  - Keefe, RSE, Harvey, PD, Khan, A, Saoud, JB, Staner, C, Davidson, M, and Luthringer, R. "Cognitive Effects of MIN-101 in Patients With Schizophrenia and Negative Symptoms: Results From a Randomized Controlled Trial." The Journal of Clinical Psychiatry 79, no. 3 (May 2018). Full Text
  - Keefe, RSE, Nomikos, G, Zhong, W, Christensen, MC, and Jacobson, W. "A Subgroup Analysis of the Impact of Vortioxetine on Functional Capacity, as Measured by UPSA, in Patients with Major Depressive Disorder and Subjective Cognitive Dysfunction." The International Journal of Neuropsychopharmacology 21, no. 5 (May 2018): 442-447. Full Text
  - Xavier, RM, Vorderstrasse, A, Keefe, RSE, and Dungan, JR. "Genetic correlates of insight in schizophrenia." Schizophrenia Research 195 (May 2018): 290-297. Full Text
  - Shafee, R, Nanda, P, Padmanabhan, JL, Tandon, N, Alliey-Rodriguez, N, Kalapurakkel, S, Weiner, DJ, Gur, RE, Keefe, RSE, Hill, SK, Bishop, JR, Clementz, BA, Tamminga, CA, Gershon, ES, Pearlson, GD, Keshavan, MS, Sweeney, JA, McCarroll, SA, and Robinson, EB. "Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls." Translational Psychiatry 8, no. 1 (April 12, 2018): 78-null. Full Text
  - Kendler, KS, Ohlsson, H, Keefe, RSE, Sundquist, K, and Sundquist, J. "The joint impact of cognitive performance in adolescence and familial cognitive aptitude on risk for major psychiatric disorders: a delineation of four potential pathways to illness." Molecular Psychiatry 23, no. 4 (April 2018): 1076-1083. Full Text
  - Xavier, RM, Pan, W, Dungan, JR, Keefe, RSE, and Vorderstrasse, A. "Unraveling interrelationships among psychopathology symptoms, cognitive domains and insight dimensions in chronic schizophrenia." Schizophrenia Research 193 (March 2018): 83-90. Full Text
  - Healey, KM, Penn, DL, Perkins, D, Woods, SW, Keefe, RSE, and Addington, J. "Latent Profile Analysis and Conversion to Psychosis: Characterizing Subgroups to Enhance Risk Prediction." Schizophrenia Bulletin 44, no. 2 (February 2018): 286-296. Full Text
  - Hochberger, WC, Combs, T, Reilly, JL, Bishop, JR, Keefe, RSE, Clementz, BA, Keshavan, MS, Pearlson, GD, Tamminga, CA, Hill, SK, and Sweeney, JA. "Deviation from expected cognitive ability across psychotic disorders." Schizophrenia Research 192 (February 2018): 300-307. Full Text
  - Atkins, AS, Khan, A, Ulshen, D, Vaughan, A, Balentin, D, Dickerson, H, Liharska, LE, Plassman, B, Welsh-Bohmer, K, and Keefe, RSE. "Assessment of Instrumental Activities of Daily Living in Older Adults with Subjective Cognitive Decline Using the Virtual Reality Functional Capacity Assessment Tool (VRFCAT)." The Journal of Prevention of Alzheimer'S Disease 5, no. 4 (January 2018): 216-234. Full Text
  - Romero, HR, Monsch, AU, Hayden, KM, Plassman, BL, Atkins, AS, Keefe, RSE, Brewster, S, Chiang, C, O'Neil, J, Runyan, G, Atkinson, MJ, Crawford, S, Budur, K, Burns, DK, and Welsh-Bohmer, KA. "TOMMORROW neuropsychological battery: German language validation and normative study." Alzheimer'S & Dementia (New York, N. Y.) 4 (January 2018): 314-323. Full Text
  - Ang, MS, Abdul Rashid, NA, Lam, M, Rapisarda, A, Kraus, M, Keefe, RSE, and Lee, J. "The Impact of Medication Anticholinergic Burden on Cognitive Performance in People With Schizophrenia." Journal of Clinical Psychopharmacology 37, no. 6 (December 2017): 651-656. Full Text
  - Georgiades, A, Davis, VG, Atkins, AS, Khan, A, Walker, TW, Loebel, A, Haig, G, Hilt, DC, Dunayevich, E, Umbricht, D, Sand, M, and Keefe, RSE. "Psychometric characteristics of the MATRICS Consensus Cognitive Battery in a large pooled cohort of stable schizophrenia patients." Schizophrenia Research 190 (December 2017): 172-179. Full Text
  - Harvey, PD, Khan, A, and Keefe, RSE. "Using the Positive and Negative Syndrome Scale (PANSS) to Define Different Domains of Negative Symptoms: Prediction of Everyday Functioning by Impairments in Emotional Expression and Emotional Experience." Innovations in clinical neuroscience 14, no. 11-12 (December 2017): 18-22.
  - Khan, A, Liharska, L, Harvey, PD, Atkins, A, Ulshen, D, and Keefe, RSE. "Negative Symptom Dimensions of the Positive and Negative Syndrome Scale Across Geographical Regions: Implications for Social, Linguistic, and Cultural Consistency." Innovations in clinical neuroscience 14, no. 11-12 (December 2017): 30-40.
  - Lam, M, Wang, M, Huang, W, Eng, GK, Rapisarda, A, Kraus, M, Kang, S, Keefe, RSE, and Lee, J. "Establishing the Brief Assessment of Cognition - Short form." Journal of psychiatric research 93 (October 2017): 1-11. Full Text
  - Cella, M, Stahl, D, Morris, S, Keefe, RSE, Bell, MD, and Wykes, T. "Effects of cognitive remediation on negative symptoms dimensions: exploring the role of working memory." Psychological Medicine (September 4, 2017): 1-9. Full Text
  - Keefe, RSE, Davis, VG, Harvey, PD, Atkins, AS, Haig, GM, Hagino, O, Marder, S, Hilt, DC, and Umbricht, D. "Placebo Response and Practice Effects in Schizophrenia Cognition Trials." Jama Psychiatry 74, no. 8 (August 2017): 807-814. Full Text
  - Mazhari, S, Ghafaree-Nejad, AR, Soleymani-Zade, S, and Keefe, RSE. "Validation of the Persian version of the Schizophrenia Cognition Rating Scale (SCoRS) in patients with schizophrenia." Asian journal of psychiatry 27 (June 2017): 12-15. Full Text
  - Keefe, RSE, and Kahn, RS. "Cognitive Decline and Disrupted Cognitive Trajectory in Schizophrenia." Jama Psychiatry 74, no. 5 (May 2017): 535-536. Full Text
  - Atkins, AS, Tseng, T, Vaughan, A, Twamley, EW, Harvey, P, Patterson, T, Narasimhan, M, and Keefe, RSE. "Validation of the tablet-administered Brief Assessment of Cognition (BAC App)." Schizophrenia research 181 (March 2017): 100-106. Full Text
  - Reilly, JL, Hill, SK, Gold, JM, Keefe, RSE, Clementz, BA, Gershon, E, Keshavan, MS, Pearlson, G, Tamminga, CA, and Sweeney, JA. "Impaired Context Processing is Attributable to Global Neuropsychological Impairment in Schizophrenia and Psychotic Bipolar Disorder." Schizophrenia Bulletin 43, no. 2 (March 2017): 397-406. Full Text
  - Addington, J, Liu, L, Perkins, DO, Carrion, RE, Keefe, RSE, and Woods, SW. "The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms." Schizophrenia Bulletin 43, no. 1 (January 2017): 57-63. Full Text
  - Kraus, M, Rapisarda, A, Lam, M, Thong, JYJ, Lee, J, Subramaniam, M, Collinson, SL, Chong, SA, and Keefe, RSE. "Disrupted latent inhibition in individuals at ultra high-risk for developing psychosis." Schizophrenia Research. Cognition 6 (December 2016): 1-8. Full Text
  - Mahableshwarkar, AR, Zajecka, J, Jacobson, W, Chen, Y, and Keefe, RS. "A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 41, no. 12 (November 2016): 2961-null. Full Text
  - Kantrowitz, JT, Medalia, A, Keefe, RSE, Harvey, PD, Bruder, G, Barch, DM, Choo, T, Lee, S, and Lieberman, JA. "Dr Kantrowitz and Colleagues Reply." The Journal of Clinical Psychiatry 77, no. 10 (October 2016): e1353-null. (Letter) Full Text
  - Wang, C, Ji, F, Hong, Z, Poh, JS, Krishnan, R, Lee, J, Rekhi, G, Keefe, RSE, Adcock, RA, Wood, SJ, Fornito, A, Pasternak, O, Chee, MWL, and Zhou, J. "Disrupted salience network functional connectivity and white-matter microstructure in persons at risk for psychosis: findings from the LYRIKS study." Psychological Medicine 46, no. 13 (October 2016): 2771-2783. Full Text
  - Keefe, RSE, Davis, VG, Atkins, AS, Vaughan, A, Patterson, T, Narasimhan, M, and Harvey, PD. "Validation of a Computerized test of Functional Capacity." Schizophrenia Research 175, no. 1-3 (August 2016): 90-96. Full Text
  - Cruz, BF, Resende, CBD, Carvalhaes, CF, Cardoso, CS, Teixeira, AL, Keefe, RS, Rocha, FL, and Salgado, JV. "Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms." Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999) 38, no. 3 (July 2016): 216-221. Full Text
  - Lim, J, Lee, S-A, Lam, M, Rapisarda, A, Kraus, M, Keefe, RSE, and Lee, J. "The relationship between negative symptom subdomains and cognition." Psychological Medicine 46, no. 10 (July 2016): 2169-2177. Full Text
  - Kantrowitz, JT, Sharif, Z, Medalia, A, Keefe, RSE, Harvey, P, Bruder, G, Barch, DM, Choo, T, Lee, S, and Lieberman, JA. "A Multicenter, Rater-Blinded, Randomized Controlled Study of Auditory Processing-Focused Cognitive Remediation Combined With Open-Label Lurasidone in Patients With Schizophrenia and Schizoaffective Disorder." The Journal of Clinical Psychiatry 77, no. 6 (June 2016): 799-806. Full Text
  - Keefe, RSE, and Reichenberg, A. "Predicting Schizophrenia." Jama Psychiatry 73, no. 5 (May 2016): 441-442. Full Text
  - Keefe, RSE. "Treating cognitive impairment in depression: an unmet need." The lancet. Psychiatry 3, no. 5 (May 2016): 392-393. Full Text
  - McCleery, A, Green, MF, Hellemann, GS, Baade, LE, Gold, JM, Keefe, RSE, Kern, RS, Mesholam-Gately, RI, Seidman, LJ, Subotnik, KL, Ventura, J, and Nuechterlein, KH. "Latent structure of cognition in schizophrenia: a confirmatory factor analysis of the MATRICS Consensus Cognitive Battery (MCCB)." Psychological medicine 46, no. 5 (April 2016): 1119-. Full Text
  - Walling, D, Marder, SR, Kane, J, Fleischhacker, WW, Keefe, RSE, Hosford, DA, Dvergsten, C, Segreti, AC, Beaver, JS, Toler, SM, Jett, JE, and Dunbar, GC. "Phase 2 Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) in Negative and Cognitive Symptoms of Schizophrenia." Schizophrenia Bulletin 42, no. 2 (March 2016): 335-343. Full Text
  - Hochberger, WC, Hill, SK, Nelson, CLM, Reilly, JL, Keefe, RSE, Pearlson, GD, Keshavan, MS, Tamminga, CA, Clementz, BA, and Sweeney, JA. "Unitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives." Schizophrenia Research 170, no. 1 (January 2016): 156-161. Full Text
  - Keefe, RSE, Haig, GM, Marder, SR, Harvey, PD, Dunayevich, E, Medalia, A, Davidson, M, Lombardo, I, Bowie, CR, Buchanan, RW, Bugarski-Kirola, D, Carpenter, WT, Csernansky, JT, Dago, PL, Durand, DM, Frese, FJ, Goff, DC, Gold, JM, Hooker, CI, Kopelowicz, A, Loebel, A, McGurk, SR, Opler, LA, Pinkham, AE, and Stern, RG. "Report on ISCTM Consensus Meeting on Clinical Assessment of Response to Treatment of Cognitive Impairment in Schizophrenia." Schizophrenia Bulletin 42, no. 1 (January 2016): 19-33. Full Text
  - Keefe, RSE, Meltzer, HA, Dgetluck, N, Gawryl, M, Koenig, G, Moebius, HJ, Lombardo, I, and Hilt, DC. "Randomized, Double-Blind, Placebo-Controlled Study of Encenicline, an α7 Nicotinic Acetylcholine Receptor Agonist, as a Treatment for Cognitive Impairment in Schizophrenia." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 40, no. 13 (December 2015): 3053-3060. Full Text
  - Keefe, RSE, and Harvey, PD. "Understanding symbol coding in schizophrenia." Biological psychiatry 78, no. 11 (December 2015): 744-746. Full Text
  - Klauser, P, Zhou, J, Lim, JKW, Poh, JS, Zheng, H, Tng, HY, Krishnan, R, Lee, J, Keefe, RSE, Adcock, RA, Wood, SJ, Fornito, A, and Chee, MWL. "Lack of Evidence for Regional Brain Volume or Cortical Thickness Abnormalities in Youths at Clinical High Risk for Psychosis: Findings From the Longitudinal Youth at Risk Study." Schizophrenia Bulletin 41, no. 6 (November 2015): 1285-1293. Full Text
  - Iwata, Y, Nakajima, S, Suzuki, T, Keefe, RSE, Plitman, E, Chung, JK, Caravaggio, F, Mimura, M, Graff-Guerrero, A, and Uchida, H. "Effects of glutamate positive modulators on cognitive deficits in schizophrenia: a systematic review and meta-analysis of double-blind randomized controlled trials." Molecular Psychiatry 20, no. 10 (October 2015): 1151-1160. (Review) Full Text
  - Kelly, DL, Sullivan, KM, McEvoy, JP, McMahon, RP, Wehring, HJ, Gold, JM, Liu, F, Warfel, D, Vyas, G, Richardson, CM, Fischer, BA, Keller, WR, Koola, MM, Feldman, SM, Russ, JC, Keefe, RSE, Osing, J, Hubzin, L, August, S, Walker, TM, and Buchanan, RW. "Adjunctive Minocycline in Clozapine-Treated Schizophrenia Patients With Persistent Symptoms." Journal of Clinical Psychopharmacology 35, no. 4 (August 2015): 374-381. Full Text
  - Kristian Hill, S, Buchholz, A, Amsbaugh, H, Reilly, JL, Rubin, LH, Gold, JM, Keefe, RSE, Pearlson, GD, Keshavan, MS, Tamminga, CA, and Sweeney, JA. "Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment." Schizophrenia research 166, no. 1-3 (August 2015): 310-315. Full Text
  - Hill, SK, Reilly, JL, Ragozzino, ME, Rubin, LH, Bishop, JR, Gur, RC, Gershon, ES, Tamminga, CA, Pearlson, GD, Keshavan, MS, Keefe, RSE, and Sweeney, JA. "Regressing to Prior Response Preference After Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings From the B-SNIP Study." Schizophrenia Bulletin 41, no. 4 (July 2015): 940-950. Full Text
  - Mahableshwarkar, AR, Zajecka, J, Jacobson, W, Chen, Y, and Keefe, RSE. "A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 40, no. 8 (July 2015): 2025-2037. Full Text
  - Atkins, AS, Stroescu, I, Spagnola, NB, Davis, VG, Patterson, TD, Narasimhan, M, Harvey, PD, and Keefe, RSE. "Assessment of Age-Related Differences in Functional Capacity Using the Virtual Reality Functional Capacity Assessment Tool (VRFCAT)." The Journal of Prevention of Alzheimer'S Disease 2, no. 2 (June 2015): 121-127. Full Text
  - Jarskog, LF, Lowy, MT, Grove, RA, Keefe, RSE, Horrigan, JP, Ball, MP, Breier, A, Buchanan, RW, Carter, CS, Csernansky, JG, Goff, DC, Green, MF, Kantrowitz, JT, Keshavan, MS, Laurelle, M, Lieberman, JA, Marder, SR, Maruff, P, McMahon, RP, Seidman, LJ, and Peykamian, MA. "A Phase II study of a histamine H₃ receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy." Schizophrenia research 164, no. 1-3 (May 2015): 136-142. Full Text
  - Lim, J, Rekhi, G, Rapisarda, A, Lam, M, Kraus, M, Keefe, RSE, and Lee, J. "Impact of psychiatric comorbidity in individuals at Ultra High Risk of psychosis - Findings from the Longitudinal Youth at Risk Study (LYRIKS)." Schizophrenia research 164, no. 1-3 (May 2015): 8-14. Full Text
  - Araújo, GE, Resende, CBD, Cardoso, ACA, Teixeira, AL, Keefe, RSE, and Salgado, JV. "Validity and reliability of the Brazilian Portuguese version of the BACS (Brief Assessment of Cognition in Schizophrenia)." Clinics 70, no. 4 (April 2015): 278-282. Full Text
  - Bauer, IE, Ouyang, A, Mwangi, B, Sanches, M, Zunta-Soares, GB, Keefe, RSE, Huang, H, and Soares, JC. "Reduced white matter integrity and verbal fluency impairment in young adults with bipolar disorder: a diffusion tensor imaging study." Journal of psychiatric research 62 (March 2015): 115-122. Full Text
  - Keefe, RSE, Davis, VG, Spagnola, NB, Hilt, D, Dgetluck, N, Ruse, S, Patterson, TD, Narasimhan, M, and Harvey, PD. "Reliability, validity and treatment sensitivity of the Schizophrenia Cognition Rating Scale." European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 25, no. 2 (February 2015): 176-184. Full Text
  - Bauer, IE, Keefe, RSE, Sanches, M, Suchting, R, Green, CE, and Soares, JC. "Evaluation of cognitive function in bipolar disorder using the Brief Assessment of Cognition in Affective Disorders (BAC-A)." Journal of Psychiatric Research 60 (January 2015): 81-86. Full Text
  - Graham, KA, Keefe, RS, Lieberman, JA, Calikoglu, AS, Lansing, KM, and Perkins, DO. "Relationship of low vitamin D status with positive, negative and cognitive symptom domains in people with first-episode schizophrenia." Early Intervention in Psychiatry 9, no. 5 (2015): 397-405. Full Text
  - Harvey, PD, and Keefe, RSE. "Methods for delivering and evaluating the efficacy of cognitive enhancement." Handbook of Experimental Pharmacology 228 (January 2015): 5-25. (Review) Full Text
  - Healey, KM, Combs, DR, Gibson, CM, Keefe, RSE, Roberts, DL, and Penn, DL. "Observable Social Cognition--A Rating Scale: an interview-based assessment for schizophrenia." Cognitive neuropsychiatry 20, no. 3 (January 2015): 198-221. Full Text
  - Jarskog, LF, Lowy, MT, Grove, RA, Keefe, RSE, Horrigan, JP, Ball, MP, Breier, A, Buchanan, RW, Carter, CS, Csernansky, JG, Goff, DC, Green, MF, Kantrowitz, JT, Keshavan, MS, Laurelle, M, Lieberman, JA, Marder, SR, Maruff, P, McMahon, RP, Seidman, LJ, and Peykamian, MA. "A Phase II study of a histamine H<inf>3</inf> receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy." Schizophrenia Research 164, no. 1-3 (January 1, 2015): 136-142. Full Text
  - Kaneda, Y, and Keefe, RSE. "An abbreviated version of the brief assessment of cognition in schizophrenia (BACS)." European Journal of Psychiatry 29, no. 2 (January 1, 2015): 131-134.
  - Keefe, RSE, Davis, VG, Spagnola, NB, Hilt, D, Dgetluck, N, Ruse, S, Patterson, TD, Narasimhan, M, and Harvey, PD. "Reliability, validity and treatment sensitivity of the Schizophrenia Cognition Rating Scale." European Neuropsychopharmacology 25, no. 2 (2015): 176-184. Full Text
  - Lui, S, Yao, L, Xiao, Y, Keedy, SK, Reilly, JL, Keefe, RS, Tamminga, CA, Keshavan, MS, Pearlson, GD, Gong, Q, and Sweeney, JA. "Resting-state brain function in schizophrenia and psychotic bipolar probands and their first-degree relatives." Psychological Medicine 45, no. 1 (January 2015): 97-108. Full Text
  - McCleery, A, Green, MF, Hellemann, GS, Baade, LE, Gold, JM, Keefe, RSE, Kern, RS, Mesholam-Gately, RI, Seidman, LJ, Subotnik, KL, Ventura, J, and Nuechterlein, KH. "Latent structure of cognition in schizophrenia: a confirmatory factor analysis of the MATRICS Consensus Cognitive Battery (MCCB)." Psychological Medicine 45, no. 12 (January 2015): 2657-2666. Full Text
  - Lam, M, Collinson, SL, Eng, GK, Rapisarda, A, Kraus, M, Lee, J, Chong, SA, and Keefe, RSE. "Refining the latent structure of neuropsychological performance in schizophrenia." Psychological medicine 44, no. 16 (December 2014): 3557-3570. Full Text
  - Ethridge, LE, Soilleux, M, Nakonezny, PA, Reilly, JL, Hill, SK, Keefe, RSE, Gershon, ES, Pearlson, GD, Tamminga, CA, Keshavan, MS, and Sweeney, JA. "Behavioral response inhibition in psychotic disorders: diagnostic specificity, familiality and relation to generalized cognitive deficit." Schizophrenia research 159, no. 2-3 (November 2014): 491-498. Full Text
  - Gray, BE, McMahon, RP, Green, MF, Seidman, LJ, Mesholam-Gately, RI, Kern, RS, Nuechterlein, KH, Keefe, RS, and Gold, JM. "Detecting reliable cognitive change in individual patients with the MATRICS Consensus Cognitive Battery." Schizophrenia Research 159, no. 1 (October 2014): 182-187. Full Text
  - Hufford, MR, Davis, VG, Hilt, D, Dgetluck, N, Geffen, Y, Loebel, A, Haig, G, Santarelli, L, and Keefe, RSE. "Circadian rhythms in cognitive functioning among patients with schizophrenia: impact on signal detection in clinical trials of potential pro-cognitive therapies." Schizophrenia research 159, no. 1 (October 2014): 205-210. Full Text
  - Keefe, RSE, Fox, KH, Davis, VG, Kennel, C, Walker, TM, Burdick, KE, and Harvey, PD. "The Brief Assessment of Cognition In Affective Disorders (BAC-A):performance of patients with bipolar depression and healthy controls." Journal of affective disorders 166 (September 2014): 86-92. Full Text
  - Keefe, RSE. "Cognition and motivation as treatment targets in schizophrenia." JAMA psychiatry 71, no. 9 (September 2014): 987-988. Full Text
  - Marx, CE, Lee, J, Subramaniam, M, Rapisarda, A, Bautista, DCT, Chan, E, Kilts, JD, Buchanan, RW, Wai, EP, Verma, S, Sim, K, Hariram, J, Jacob, R, Keefe, RSE, and Chong, SA. "Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia." Psychopharmacology 231, no. 17 (September 2014): 3647-3662. Full Text
  - Marx, CE, Lee, J, Subramaniam, M, Rapisarda, A, Bautista, DCT, Chan, E, Kilts, JD, Buchanan, RW, Wai, EP, Verma, S, Sim, K, Hariram, J, Jacob, R, Keefe, RSE, and Chong, SA. "Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia." Psychopharmacology 231, no. 17 (September 1, 2014): 3647-3662. Full Text
  - Reilly, JL, Frankovich, K, Hill, S, Gershon, ES, Keefe, RSE, Keshavan, MS, Pearlson, GD, Tamminga, CA, and Sweeney, JA. "Elevated antisaccade error rate as an intermediate phenotype for psychosis across diagnostic categories." Schizophrenia Bulletin 40, no. 5 (September 2014): 1011-1021. Full Text
  - Stout, JC, Queller, S, Baker, KN, Cowlishaw, S, Sampaio, C, Fitzer-Attas, C, Borowsky, B, and HD-CAB Investigators, . "HD-CAB: a cognitive assessment battery for clinical trials in Huntington's disease 1,2,3." Movement disorders : official journal of the Movement Disorder Society 29, no. 10 (September 2014): 1281-1288. Full Text
  - Keefe, RSE, McClintock, SM, Roth, RM, Doraiswamy, PM, Tiger, S, and Madhoo, M. "Cognitive effects of pharmacotherapy for major depressive disorder: a systematic review." The Journal of clinical psychiatry 75, no. 8 (August 2014): 864-876. (Review) Full Text
  - Yong, E, Barbato, M, Penn, DL, Keefe, RSE, Woods, SW, Perkins, DO, and Addington, J. "Exploratory analysis of social cognition and neurocognition in individuals at clinical high risk for psychosis." Psychiatry research 218, no. 1-2 (August 2014): 39-43. Full Text
  - Dandash, O, Fornito, A, Lee, J, Keefe, RSE, Chee, MWL, Adcock, RA, Pantelis, C, Wood, SJ, and Harrison, BJ. "Altered striatal functional connectivity in subjects with an at-risk mental state for psychosis." Schizophrenia Bulletin 40, no. 4 (July 2014): 904-913. Full Text
  - Rapisarda, A, Kraus, M, Tan, YW, Lam, M, Eng, GK, Lee, J, Subramaniam, M, Collinson, SL, Chong, SA, and Keefe, RSE. "The continuous performance test, identical pairs: norms, reliability and performance in healthy controls and patients with schizophrenia in Singapore." Schizophrenia research 156, no. 2-3 (July 2014): 233-240. Full Text
  - Umbricht, D, Keefe, RSE, Murray, S, Lowe, DA, Porter, R, Garibaldi, G, and Santarelli, L. "A randomized, placebo-controlled study investigating the nicotinic α7 agonist, RG3487, for cognitive deficits in schizophrenia." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 39, no. 7 (June 2014): 1568-1577. Full Text
  - Madhoo, M, Keefe, RSE, Roth, RM, Sambunaris, A, Wu, J, Trivedi, MH, Anderson, CS, and Lasser, R. "Lisdexamfetamine dimesylate augmentation in adults with persistent executive dysfunction after partial or full remission of major depressive disorder." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 39, no. 6 (May 2014): 1388-1398. Full Text
  - Ruse, SA, Davis, VG, Atkins, AS, Krishnan, KRR, Fox, KH, Harvey, PD, and Keefe, RSE. "Development of a virtual reality assessment of everyday living skills." Journal of Visualized Experiments : Jove , no. 86 (April 23, 2014). Full Text
  - Ruse, SA, Harvey, PD, Davis, VG, Atkins, AS, Fox, KH, and Keefe, RSE. "Virtual Reality Functional Capacity Assessment In Schizophrenia: Preliminary Data Regarding Feasibility and Correlations with Cognitive and Functional Capacity Performance." Schizophrenia Research. Cognition 1, no. 1 (March 2014): e21-e26. Full Text
  - Gray, BE, McMahon, RP, Green, MF, Seidman, LJ, Mesholam-Gately, RI, Kern, RS, Nuechterlein, KH, Keefe, RS, and Gold, JM. "Detecting reliable cognitive change in individual patients with the MATRICS Consensus Cognitive Battery." Schizophrenia Research 159, no. 1 (2014): 182-187. Full Text
  - Hufford, MR, Davis, VG, Hilt, D, Dgetluck, N, Geffen, Y, Loebel, A, Haig, G, Santarelli, L, and Keefe, RSE. "Circadian rhythms in cognitive functioning among patients with schizophrenia: Impact on signal detection in clinical trials of potential pro-cognitive therapies." Schizophrenia Research 159, no. 1 (2014): 205-210. Full Text
  - Keefe, RSE. "The longitudinal course of cognitive impairment in schizophrenia: an examination of data from premorbid through posttreatment phases of illness." The Journal of clinical psychiatry 75 Suppl 2 (January 2014): 8-13. (Review) Full Text
  - Lam, M, Collinson, SL, Eng, GK, Rapisarda, A, Kraus, M, Lee, J, Chong, SA, and Keefe, RSE. "Refining the latent structure of neuropsychological performance in schizophrenia." Psychological Medicine 44, no. 16 (January 1, 2014): 3557-3570. Full Text
  - Madhoo, M, Keefe, RSE, Roth, RM, Sambunaris, A, Wu, J, Trivedi, MH, Anderson, CS, and Lasser, R. "Lisdexamfetamine dimesylate augmentation in adults with persistent executive dysfunction after partial or full remission of major depressive disorder." Neuropsychopharmacology 39, no. 6 (2014): 1388-1398. Full Text
  - Mazhari, S, Parvaresh, N, Shahrbabaki, ME, Sadeghi, MM, Nakhaee, N, and Keefe, RSE. "Validation of the Persian version of the brief assessment of cognition in schizophrenia in patients with schizophrenia and healthy controls." Psychiatry and clinical neurosciences 68, no. 2 (2014): 160-166. Full Text
  - Meier, MH, Caspi, A, Reichenberg, A, Keefe, RSE, Fisher, HL, Harrington, H, Houts, R, Poulton, R, and Moffitt, TE. "Neuropsychological decline in schizophrenia from the premorbid to the postonset period: evidence from a population-representative longitudinal study." The American Journal of Psychiatry 171, no. 1 (January 2014): 91-101. Full Text
  - Rapisarda, A, Kraus, M, Tan, YW, Lam, M, Eng, GK, Lee, J, Subramaniam, M, Collinson, SL, Chong, SA, and Keefe, RSE. "The continuous performance test, identical pairs: Norms, reliability and performance in healthy controls and patients with schizophrenia in Singapore." Schizophrenia Research 156, no. 2-3 (January 1, 2014): 233-240. Full Text
  - Ruse, SA, Davis, VG, Atkins, AS, Krishnan, KRR, Fox, KH, Harvey, PD, and Keefe, RSE. "Development of a virtual reality assessment of everyday living skills." Journal of visualized experiments : JoVE , no. 86 (2014). Full Text
  - Umbricht, D, Keefe, RSE, Murray, S, Lowe, DA, Porter, R, Garibaldi, G, and Santarelli, L. "A randomized, placebo-controlled study investigating the nicotinic 7 agonist, RG3487, for cognitive deficits in schizophrenia." Neuropsychopharmacology 39, no. 7 (2014): 1568-1577. Full Text
  - Yong, E, Barbato, M, Penn, DL, Keefe, RSE, Woods, SW, Perkins, DO, and Addington, J. "Exploratory analysis of social cognition and neurocognition in individuals at clinical high risk for psychosis." Psychiatry Research 218, no. 1-2 (2014): 39-43. Full Text
  - Abdul Rashid, NA, Lim, J, Lam, M, Chong, SA, Keefe, RSE, and Lee, J. "Unraveling the relationship between obesity, schizophrenia and cognition." Schizophrenia Research 151, no. 1-3 (December 1, 2013): 107-112. Full Text
  - Eng, GK, Lam, M, Bong, YL, Subramaniam, M, Bautista, D, Rapisarda, A, Kraus, M, Lee, J, Collinson, SL, Chong, SA, and Keefe, RSE. "Brief Assessment of Cognition in Schizophrenia: Normative Data in an English-Speaking Ethnic Chinese Sample." ARCHIVES OF CLINICAL NEUROPSYCHOLOGY 28, no. 8 (December 2013): 845-858. Full Text Link to Item
  - Lee, J, Rekhi, G, Mitter, N, Bong, YL, Kraus, MS, Lam, M, Rapisarda, A, Lee, T-S, Subramaniam, M, Chong, SA, and Keefe, RSE. "The Longitudinal Youth at Risk Study (LYRIKS)--an Asian UHR perspective." Schizophr Res 151, no. 1-3 (December 2013): 279-283. Full Text Link to Item
  - Lee, J, Rekhi, G, Mitter, N, Bong, YL, Kraus, MS, Lam, M, Rapisarda, A, Lee, TS, Subramaniam, M, Chong, SA, and Keefe, RSE. "The Longitudinal Youth at Risk Study (LYRIKS) - An Asian UHR perspective." Schizophrenia Research 151, no. 1-3 (December 1, 2013): 279-283. Full Text
  - Meier, MH, Shalev, I, Moffitt, TE, Kapur, S, Keefe, RSE, Wong, TY, Belsky, DW, Harrington, H, Hogan, S, Houts, R, Caspi, A, and Poulton, R. "Microvascular abnormality in schizophrenia as shown by retinal imaging." The American Journal of Psychiatry 170, no. 12 (December 2013): 1451-1459. Full Text
  - Hill, SK, Reilly, JL, Keefe, RSE, Gold, JM, Bishop, JR, Gershon, ES, Tamminga, CA, Pearlson, GD, Keshavan, MS, and Sweeney, JA. "Neuropsychological impairments in schizophrenia and psychotic bipolar disorder: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study." The American Journal of Psychiatry 170, no. 11 (November 2013): 1275-1284. Full Text
  - Marder, SR, Alphs, L, Anghelescu, I-G, Arango, C, Barnes, TRE, Caers, I, Daniel, DG, Dunayevich, E, Fleischhacker, WW, Garibaldi, G, Green, MF, Harvey, PD, Kahn, RS, Kane, JM, Keefe, RSE, Kinon, B, Leucht, S, Lindenmayer, J-P, Malhotra, AK, Stauffer, V, Umbricht, D, Wesnes, K, Kapur, S, and Rabinowitz, J. "Issues and perspectives in designing clinical trials for negative symptoms in schizophrenia." Schizophrenia Research 150, no. 2-3 (November 2013): 328-333. (Review) Full Text
  - Yaakub, SN, Dorairaj, K, Poh, JS, Asplund, CL, Krishnan, R, Lee, J, Keefe, RSE, Adcock, RA, Wood, SJ, and Chee, MWL. "Preserved working memory and altered brain activation in persons at risk for psychosis." The American Journal of Psychiatry 170, no. 11 (November 2013): 1297-1307. Full Text
  - Kahn, RS, and Keefe, RSE. "Schizophrenia is a cognitive illness: time for a change in focus." Jama Psychiatry 70, no. 10 (October 2013): 1107-1112. Full Text
  - Nutt, D, Gispen-de Wied, CC, Arango, C, Keefe, RSE, Penadés, R, Murphy, DG, Robbins, TW, and Sahakian, BJ. "Cognition in schizophrenia: summary Nice Consultation Meeting 2012." European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology 23, no. 8 (August 2013): 769-778. Full Text
  - Jarskog, LF, Dong, Z, Kangarlu, A, Colibazzi, T, Girgis, RR, Kegeles, LS, Barch, DM, Buchanan, RW, Csernansky, JG, Goff, DC, Harms, MP, Javitt, DC, Keefe, RS, McEvoy, JP, McMahon, RP, Marder, SR, Peterson, BS, and Lieberman, JA. "Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 38, no. 7 (June 2013): 1245-1252. Full Text
  - Keefe, RSE, Kraemer, HC, Epstein, RS, Frank, E, Haynes, G, Laughren, TP, McNulty, J, Reed, SD, Sanchez, J, and Leon, AC. "Defining a clinically meaningful effect for the design and interpretation of randomized controlled trials." Innovations in Clinical Neuroscience 10, no. 5-6 (May 1, 2013).
  - Keefe, RSE, Kraemer, HC, Epstein, RS, Frank, E, Haynes, G, Laughren, TP, McNulty, J, Reed, SD, Sanchez, J, and Leon, AC. "Defining a clinically meaningful effect for the design and interpretation of randomized controlled trials." Innov Clin Neurosci 10, no. 5-6 Suppl A (May 2013): 4S-19S. Link to Item
  - Sakurai, H, Bies, RR, Stroup, ST, Keefe, RSE, Rajji, TK, Suzuki, T, Mamo, DC, Pollock, BG, Watanabe, K, Mimura, M, and Uchida, H. "Dopamine D2 receptor occupancy and cognition in schizophrenia: analysis of the CATIE data." Schizophrenia Bulletin 39, no. 3 (May 2013): 564-574. Full Text
  - Ventura, J, Reise, SP, Keefe, RSE, Hurford, IM, Wood, RC, and Bilder, RM. "The Cognitive Assessment Interview (CAI): reliability and validity of a brief interview-based measure of cognition." Schizophrenia Bulletin 39, no. 3 (May 2013): 583-591. Full Text
  - Keefe, RSE, Buchanan, RW, Marder, SR, Schooler, NR, Dugar, A, Zivkov, M, and Stewart, M. "Clinical trials of potential cognitive-enhancing drugs in schizophrenia: what have we learned so far?." Schizophrenia Bulletin 39, no. 2 (March 2013): 417-435. (Review) Full Text
  - Lam, M, Eng, GK, Rapisarda, A, Subramaniam, M, Kraus, M, Keefe, RSE, and Collinson, SL. "Formulation of the Age-Education Index: Measuring Age and Education Effects in Neuropsychological Performance." PSYCHOLOGICAL ASSESSMENT 25, no. 1 (March 2013): 61-70. Full Text Link to Item
  - Barbato, M, Colijn, MA, Keefe, RSE, Perkins, DO, Woods, SW, Hawkins, KA, Christensen, BK, and Addington, J. "The course of cognitive functioning over six months in individuals at clinical high risk for psychosis." Psychiatry Research 206, no. 2-3 (January 1, 2013): 195-199.
  - Barbato, M, Liu, L, Penn, DL, Keefe, RSE, Perkins, DO, Woods, SW, and Addington, J. "Social cognition as a mediator between neurocognition and functional outcome in individuals at clinical high risk for psychosis." Schizophrenia Research 150, no. 2-3 (2013): 542-546. Full Text
  - Barbato, M, Liu, L, Penn, DL, Keefe, RSE, Perkins, DO, Woods, SW, and Addington, J. "Social cognition as a mediator between neurocognition and functional outcome in individuals at clinical high risk for psychosis." Schizophrenia Research (2013). Full Text
  - Cruz, BF, Resende, CBD, Abreu, MN, Rocha, FL, Teixeira, AL, Keefe, RSE, and Salgado, JV. "How specific are negative symptoms and cognitive impairment in schizophrenia? An analysis of PANSS and SCoRS." Cognitive Neuropsychiatry 18, no. 3 (2013): 243-251. Full Text
  - Jarskog, LF, Dong, Z, Kangarlu, A, Colibazzi, T, Girgis, RR, Kegeles, LS, Barch, DM, Buchanan, RW, Csernansky, JG, Goff, DC, Harms, MP, Javitt, DC, Keefe, RS, McEvoy, JP, McMahon, RP, Marder, SR, Peterson, BS, and Lieberman, JA. "Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia." Neuropsychopharmacology 38, no. 7 (2013): 1245-1252. Full Text
  - Kim, JL, Rele, S, Marks, DM, Masand, PS, Yerramsetty, P, Millet, RA, Keefe, RS, and Patkar, AA. "Effects of milnacipran on neurocognition, pain, and fatigue in fibromyalgia: a 13-week, randomized, placebo-controlled, crossover trial." The Primary Care Companion for Cns Disorders 15, no. 6 (January 2013). Full Text
  - Lee, T-S, Goh, SJA, Quek, SY, Phillips, R, Guan, C, Cheung, YB, Feng, L, Teng, SSW, Wang, CC, Chin, ZY, Zhang, H, Ng, TP, Lee, J, Keefe, R, and Krishnan, KRR. "A brain-computer interface based cognitive training system for healthy elderly: a randomized control pilot study for usability and preliminary efficacy." Plos One 8, no. 11 (January 2013): e79419-null. Full Text
  - Marder, SR, Alphs, L, Anghelescu, I-G, Arango, C, Barnes, TRE, Caers, I, Daniel, DG, Dunayevich, E, Fleischhacker, WW, Garibaldi, G, and al, E. "Issues and perspectives in designing clinical trials for negative symptoms in schizophrenia." Schizophrenia Research 150, no. 2-3 (2013): 328-333. Full Text
  - Mazhari, S, Parvaresh, N, Shahrbabaki, ME, Sadeghi, MM, Nakhaee, N, and Keefe, RSE. "Validation of the Persian version of the Brief Assessment of Cognition in Schizophrenia in patients with schizophrenia and healthy controls." Psychiatry and Clinical Neurosciences (2013). Full Text
  - Nutt, D, Wied, CCG-D, Arango, C, Keefe, RSE, Penadés, R, Murphy, DG, Robbins, TW, and Sahakian, BJ. "Cognition in schizophrenia: Summary nice consultation meeting 2012." European Neuropsychopharmacology 23, no. 8 (2013): 769-778. Full Text
  - Rapisarda, A, Lim, TF, Lim, M, Collinson, SL, Kraus, MS, and Keefe, RSE. "Applicability of the MATRICS Consensus Cognitive Battery in Singapore." Clinical Neuropsychologist (2013). Full Text
  - Rapisarda, A, Lim, TF, Lim, M, Collinson, SL, Kraus, MS, and Keefe, RSE. "Applicability of the MATRICS consensus cognitive battery in Singapore." Clinical Neuropsychologist 27, no. 3 (2013): 455-469. Full Text
  - Rashid, NAA, Lim, J, Lam, M, Chong, S-A, Keefe, RSE, and Lee, J. "Unraveling the relationship between obesity, schizophrenia and cognition." Schizophrenia Research (2013). Full Text
  - Vita, A, Deste, G, Barlati, S, Peri, LD, Giambra, A, Poli, R, Keefe, RSE, and Sacchetti, E. "Interview-based assessment of cognition in schizophrenia: Applicability of the Schizophrenia Cognition Rating Scale (SCoRS) in different phases of illness and settings of care." Schizophrenia Research (2013). Full Text
  - Vita, A, Deste, G, Barlati, S, Peri, LD, Giambra, A, Poli, R, Keefe, RSE, and Sacchetti, E. "Interview-based assessment of cognition in schizophrenia: Applicability of the Schizophrenia Cognition Rating Scale (SCoRS) in different phases of illness and settings of care." Schizophrenia Research 146, no. 1-3 (2013): 217-223. Full Text
  - Harvey, PD, and Keefe, RS. "Technology, society, and mental illness: Challenges and opportunities for assessment and treatment." Innovations in Clinical Neuroscience 9, no. 11-12 (December 1, 2012): 47-50.
  - Kahn, PV, Walker, TM, Williams, TS, Cornblatt, BA, Mohs, RC, and Keefe, RSE. "Standardizing the use of the Continuous Performance Test in schizophrenia research: a validation study." Schizophrenia Research 142, no. 1-3 (December 2012): 153-158. Full Text
  - Meier, MH, Caspi, A, Ambler, A, Harrington, H, Houts, R, Keefe, RSE, McDonald, K, Ward, A, Poulton, R, and Moffitt, TE. "Persistent cannabis users show neuropsychological decline from childhood to midlife." Proceedings of the National Academy of Sciences of the United States of America 109, no. 40 (October 2012): E2657-E2664. Full Text
  - Keefe, RSE, Vinogradov, S, Medalia, A, Buckley, PF, Caroff, SN, D'Souza, DC, Harvey, PD, Graham, KA, Hamer, RM, Marder, SM, Miller, DD, Olson, SJ, Patel, JK, Velligan, D, Walker, TM, Haim, AJ, and Stroup, TS. "Feasibility and pilot efficacy results from the multisite Cognitive Remediation in the Schizophrenia Trials Network (CRSTN) randomized controlled trial." The Journal of Clinical Psychiatry 73, no. 7 (July 2012): 1016-1022. Full Text
  - Javitt, DC, Buchanan, RW, Keefe, RSE, Kern, R, McMahon, RP, Green, MF, Lieberman, J, Goff, DC, Csernansky, JG, McEvoy, JP, Jarskog, F, Seidman, LJ, Gold, JM, Kimhy, D, Nolan, KS, Barch, DS, Ball, MP, Robinson, J, and Marder, SR. "Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia." Schizophrenia Research 136, no. 1-3 (April 2012): 25-31. Full Text
  - Barbato, M, Colijn, MA, Keefe, RSE, Perkins, DO, Woods, SW, Hawkins, KA, Christensen, BK, and Addington, J. "The course of cognitive functioning over six months in individuals at clinical high risk for psychosis." Psychiatry Research (2012). Full Text
  - Cruz, BF, Resende, CBD, Abreu, MN, Fá, FLR, Teixeira, AL, Keefe, RSE, and SalgadoJoã, JV. "How specific are negative symptoms and cognitive impairment in schizophrenia? An analysis of PANSS and SCoRS." Cognitive Neuropsychiatry (2012). Full Text
  - Geffen, Y, Keefe, R, Rabinowitz, J, Anand, R, and Davidson, M. "BL-1020, a new γ-aminobutyric acid-enhanced antipsychotic: Results of 6-week, randomized, double-blind, controlled, efficacy and safety study." Journal of Clinical Psychiatry 73, no. 9 (2012): e1168-e1174. Full Text
  - Keefe, RSE, and Harvey, PD. "Cognitive impairment in schizophrenia." Handbook of Experimental Pharmacology , no. 213 (January 2012): 11-37. (Review) Full Text
  - Keefe, RSE, and Kraus, MS. "Clues to the cognitive and perceptual origins of social isolation and psychosis in schizophrenia." American Journal of Psychiatry 169, no. 4 (2012): 354-357. Full Text
  - Krishnan, RR, Fivaz, M, Kraus, MS, and Keefe, RSE. "Erratum: Hierarchical temporal processing deficit model of reality distortion and psychoses (Molecular Psychiatry (2011) 16, (129-144) DOI: 10.1038/mp.2010.63)." Molecular Psychiatry 17, no. 4 (January 1, 2012): 470-null. Full Text
  - Matza, LS, Phillips, GA, Revicki, DA, Ascher-Svanum, H, Malley, KG, Palsgrove, AC, Faries, DE, Stauffer, V, Kinon, BJ, Awad, AG, Keefe, RS, and Naber, D. "Validation of a patient interview for assessing reasons for antipsychotic discontinuation and continuation." Patient Preference and Adherence 6 (January 2012): 521-532. Full Text
  - Matza, LS, Phillips, GA, Revicki, DA, Ascher-Svanum, H, Malley, KG, Palsgrove, AC, Faries, DE, Stauffer, V, Kinon, BJ, Awad, AG, Keefe, RSE, and Naber, D. "Validation of a clinician questionnaire to assess reasons for antipsychotic discontinuation and continuation among patients with schizophrenia." Psychiatry Research 200, no. 2-3 (2012): 835-842. Full Text
  - Matza, LS, Phillips, GA, Revicki, DA, Ascher-Svanum, H, Malley, KG, Palsgrove, AC, Faries, DE, Stauffer, V, Kinon, BJ, Awad, AG, and al, E. "Validation of a clinician questionnaire to assess reasons for antipsychotic discontinuation and continuation among patients with schizophrenia." Psychiatry Research (2012). Full Text
  - Weiser, M, Gershon, AA, Rubinstein, K, Petcu, C, Ladea, M, Sima, D, Podea, D, Keefe, RSE, and Davis, JM. "A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder." Schizophrenia Research 138, no. 1 (2012): 35-38. Full Text
  - Greenberg, G, Rosenheck, RA, Erickson, SK, Desai, RA, Stefanovics, EA, Swartz, M, Keefe, RSE, McEvoy, J, Stroup, TS, and CATIE Investigators, . "Criminal justice system involvement among people with schizophrenia." Community Mental Health Journal 47, no. 6 (December 2011): 727-736. Full Text
  - Buchanan, RW, Keefe, RSE, Umbricht, D, Green, MF, Laughren, T, and Marder, SR. "The FDA-NIMH-MATRICS guidelines for clinical trial design of cognitive-enhancing drugs: what do we know 5 years later?." Schizophrenia Bulletin 37, no. 6 (November 2011): 1209-1217. Full Text
  - Chong, S-A, Campbell, A, Chee, M, Liu, J, Marx, C, McGorry, P, Subramaniam, M, Yung, A, and Keefe, RSE. "The Singapore flagship programme in translational and clinical research in psychosis." Early Intervention in Psychiatry 5, no. 4 (November 2011): 290-300. (Review) Full Text
  - Kerfoot, KE, Rosenheck, RA, Petrakis, IL, Swartz, MS, Keefe, RSE, McEvoy, JP, Stroup, TS, and CATIE Investigators, . "Substance use and schizophrenia: adverse correlates in the CATIE study sample." Schizophrenia Research 132, no. 2-3 (November 2011): 177-182. Full Text
  - Keefe, RSE, Vinogradov, S, Medalia, A, Silverstein, SM, Bell, MD, Dickinson, D, Ventura, J, Marder, SR, and Stroup, TS. "Report from the working group conference on multisite trial design for cognitive remediation in schizophrenia." Schizophrenia Bulletin 37, no. 5 (September 2011): 1057-1065. Full Text
  - Stroup, TS, Appelbaum, PS, Gu, H, Hays, S, Swartz, MS, Keefe, RSE, Kim, SY, Manschreck, TC, Boshes, RA, McEvoy, JP, and Lieberman, JA. "Longitudinal consent-related abilities among research participants with schizophrenia: results from the CATIE study." Schizophrenia Research 130, no. 1-3 (August 2011): 47-52. Full Text
  - Vigen, CLP, Mack, WJ, Keefe, RSE, Sano, M, Sultzer, DL, Stroup, TS, Dagerman, KS, Hsiao, JK, Lebowitz, BD, Lyketsos, CG, Tariot, PN, Zheng, L, and Schneider, LS. "Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD." The American Journal of Psychiatry 168, no. 8 (August 2011): 831-839. Full Text
  - Hurford, IM, Marder, SR, Keefe, RSE, Reise, SP, and Bilder, RM. "A brief cognitive assessment tool for schizophrenia: construction of a tool for clinicians." Schizophrenia Bulletin 37, no. 3 (May 2011): 538-545. Full Text
  - Buchanan, RW, Keefe, RSE, Lieberman, JA, Barch, DM, Csernansky, JG, Goff, DC, Gold, JM, Green, MF, Jarskog, LF, Javitt, DC, Kimhy, D, Kraus, MS, McEvoy, JP, Mesholam-Gately, RI, Seidman, LJ, Ball, MP, McMahon, RP, Kern, RS, Robinson, J, and Marder, SR. "A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia." Biological Psychiatry 69, no. 5 (March 2011): 442-449. Full Text
  - Caroff, SN, Davis, VG, Miller, DD, Davis, SM, Rosenheck, RA, McEvoy, JP, Campbell, EC, Saltz, BL, Riggio, S, Chakos, MH, Swartz, MS, Keefe, RSE, Stroup, TS, Lieberman, JA, and CATIE Investigators, . "Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia." The Journal of Clinical Psychiatry 72, no. 3 (March 2011): 295-303. Full Text
  - Kern, RS, Gold, JM, Dickinson, D, Green, MF, Nuechterlein, KH, Baade, LE, Keefe, RSE, Mesholam-Gately, RI, Seidman, LJ, Lee, C, Sugar, CA, and Marder, SR. "The MCCB impairment profile for schizophrenia outpatients: results from the MATRICS psychometric and standardization study." Schizophrenia Research 126, no. 1-3 (March 2011): 124-131. Full Text
  - Marder, SR, Daniel, DG, Alphs, L, Awad, AG, and Keefe, RSE. "Methodological issues in negative symptom trials." Schizophrenia Bulletin 37, no. 2 (March 2011): 250-254. Full Text
  - Reise, SP, Ventura, J, Keefe, RSE, Baade, LE, Gold, JM, Green, MF, Kern, RS, Mesholam-Gately, R, Nuechterlein, KH, Seidman, LJ, and Bilder, R. "Bifactor and item response theory analyses of interviewer report scales of cognitive impairment in schizophrenia." Psychological Assessment 23, no. 1 (March 2011): 245-261. Full Text
  - Keefe, RSE, Fox, KH, Harvey, PD, Cucchiaro, J, Siu, C, and Loebel, A. "Characteristics of the MATRICS Consensus Cognitive Battery in a 29-site antipsychotic schizophrenia clinical trial." Schizophrenia Research 125, no. 2-3 (February 2011): 161-168. Full Text
  - Krishnan, RR, Fivaz, M, Kraus, MS, and Keefe, RSE. "Hierarchical temporal processing deficit model of reality distortion and psychoses." Molecular Psychiatry 16, no. 2 (February 2011): 129-144. Full Text
  - McClay, JL, Adkins, DE, Aberg, K, Bukszár, J, Khachane, AN, Keefe, RSE, Perkins, DO, McEvoy, JP, Stroup, TS, Vann, RE, Beardsley, PM, Lieberman, JA, Sullivan, PF, and van den Oord, EJCG. "Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 36, no. 3 (February 2011): 616-626. Full Text
  - Burdick, KE, Goldberg, TE, Cornblatt, BA, Keefe, RS, Gopin, CB, Derosse, P, Braga, RJ, and Malhotra, AK. "The MATRICS consensus cognitive battery in patients with bipolar i disorder." Neuropsychopharmacology 36, no. 8 (2011): 1587-1592. Full Text
  - Harvey, PD, Ogasa, M, Cucchiaro, J, Loebel, A, and Keefe, RSE. "Performance and interview-based assessments of cognitive change in a randomized, double-blind comparison of lurasidone vs. ziprasidone." Schizophrenia Research 127, no. 1-3 (2011): 188-194. Full Text
  - Keefe, RSE, Kraus, MS, and Krishnan, RR. "Failures in learning-dependent predictive perception as the key cognitive vulnerability to psychosis in schizophrenia." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 36, no. 1 (January 2011): 367-368. Full Text
  - Krishnan, RR, Kraus, MS, and Keefe, RSE. "Comprehensive model of how reality distortion and symptoms occur in schizophrenia: Could impairment in learning-dependent predictive perception account for the manifestations of schizophrenia?." Psychiatry and Clinical Neurosciences 65, no. 4 (2011): 305-317. Full Text
  - Sachs, G, Winklbaur, B, Jagsch, R, and Keefe, RSE. "Validation of the German version of the Brief Assessment of Cognition in Schizophrenia (BACS) - Preliminary results." European Psychiatry 26, no. 2 (2011): 74-77. Full Text
  - Segarra, N, Bernardo, M, Gutierrez, F, Justicia, A, Fernadez-Egea, E, Allas, M, Safont, G, Contreras, F, Gascon, J, Soler-Insa, PA, Menchon, JM, Junque, C, and Keefe, RSE. "Spanish validation of the Brief Assessment in Cognition in Schizophrenia (BACS) in patients with schizophrenia and healthy controls." European Psychiatry 26, no. 2 (2011): 69-73. Full Text
  - Sim, K, Lee, J, Subramaniam, M, Liu, JJ, Keefe, R, Zhang, XD, Lee, TS, and Chong, SA. "Integrated genetic and genomic approach in the Singapore translational and clinical research in psychosis study: An overview." Early Intervention in Psychiatry 5, no. 2 (2011): 91-99. Full Text
  - Kane, JM, D'Souza, DC, Patkar, AA, Youakim, JM, Tiller, JM, Yang, R, and Keefe, RSE. "Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study." The Journal of Clinical Psychiatry 71, no. 11 (November 2010): 1475-1481. Full Text
  - LaMonica, HM, Keefe, RSE, Harvey, PD, Gold, JM, and Goldberg, TE. "Differential effects of emotional information on interference task performance across the life span." FRONTIERS IN AGING NEUROSCIENCE 2 (September 30, 2010). Full Text Link to Item
  - Goldberg, TE, Keefe, RSE, Goldman, RS, Robinson, DG, and Harvey, PD. "Circumstances under which practice does not make perfect: a review of the practice effect literature in schizophrenia and its relevance to clinical treatment studies." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 35, no. 5 (April 2010): 1053-1062. (Review) Full Text
  - Polanczyk, G, Moffitt, TE, Arseneault, L, Cannon, M, Ambler, A, Keefe, RSE, Houts, R, Odgers, CL, and Caspi, A. "Etiological and clinical features of childhood psychotic symptoms: results from a birth cohort." Archives of General Psychiatry 67, no. 4 (April 2010): 328-338. Full Text
  - Reichenberg, A, Caspi, A, Harrington, H, Houts, R, Keefe, RSE, Murray, RM, Poulton, R, and Moffitt, TE. "Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study." The American Journal of Psychiatry 167, no. 2 (February 2010): 160-169. Full Text
  - Ascher-Svanum, H, Nyhuis, AW, Stauffer, V, Kinon, BJ, Faries, DE, Phillips, GA, Schuh, K, Awad, AG, Keefe, R, and Naber, D. "Reasons for discontinuation and continuation of antipsychotics in the treatment of schizophrenia from patient and clinician perspectives." Current Medical Research and Opinion 26, no. 10 (2010): 2403-2410. Full Text
  - Barch, DM, and Keefe, RSE. "Anticipating DSM-V: opportunities and challenges for cognition and psychosis." Schizophrenia Bulletin 36, no. 1 (January 2010): 43-47. Full Text
  - Chan, W-Y, Yang, G-L, Chia, M-Y, Woon, P-S, Lee, J, Keefe, R, Sitoh, Y-Y, Nowinski, WL, and Sim, K. "Cortical and subcortical white matter abnormalities in adults with remitted first-episode mania revealed by Tract-Based Spatial Statistics." Bipolar Disorders 12, no. 4 (2010): 383-389. Full Text
  - Chia, MY, Chan, WY, Chua, KY, Lee, H, Lee, J, Lee, R, Lim, C, Tay, E, Woon, PS, Keefe, RSE, and Sim, K. "The Schizophrenia cognition Rating Scale: Validation of an interview-based assessment of cognitive functioning in Asian patients with schizophrenia." Psychiatry Research 178, no. 1 (2010): 33-38. Full Text
  - Keefe, RSE. "Neurocognition." (January 1, 2010): 97-119. (Chapter) Full Text
  - Konneker, TI, Crowley, JJ, Quackenbush, CR, Keefe, RSE, Perkins, DO, Stroup, TS, Lieberman, JA, Oord, EVD, and Sullivan, PF. "No association of the serotonin transporter polymorphisms 5-HTTLPR and rs25531 with schizophrenia or neurocognition." American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 153, no. 5 (2010): 1115-1117. Full Text
  - Seidman, LJ, Giuliano, AJ, Meyer, EC, Addington, J, Cadenhead, KS, Cannon, TD, McGlashan, TH, Perkins, DO, Tsuang, MT, Walker, EF, Woods, SW, Bearden, CE, Christensen, BK, Hawkins, K, Heaton, R, Keefe, RSE, Heinssen, R, and Cornblatt, BA. "Neuropsychology of the prodrome to psychosis in the NAPLS Consortium: Relationship to family history and conversion to psychosis." Archives of General Psychiatry 67, no. 6 (2010): 578-588. Full Text
  - Ventura, J, Reise, SP, Keefe, RSE, Baade, LE, Gold, JM, Green, MF, Kern, RS, Mesholam-Gately, R, Nuechterlein, KH, Seidman, LJ, and Bilder, RM. "The Cognitive Assessment Interview (CAI): Development and validation of an empirically derived, brief interview-based measure of cognition." Schizophrenia Research 121, no. 1-3 (2010): 24-31. Full Text
  - Pinheiro, AP, Keefe, RSE, Skelly, T, Olarte, M, Leviel, K, Lange, LA, Lange, EM, Stroup, TS, Lieberman, J, and Sullivan, PF. "Erratum: AKT1 and neurocognition in schizophrenia (Australian and New Zealand Journal of Psychiatry (2007) 41 (169-177))." Australian and New Zealand Journal of Psychiatry 43, no. 10 (December 8, 2009): 983-null. Full Text
  - Fox, KH, Burdick, KE, Lombardo, I, and Keefe, RSE. "Cognitive impairment in patients with bipolar disorder." Psychiatric Times 26, no. 12 (December 1, 2009): 66-68.
  - Penn, DL, Keefe, RSE, Davis, SM, Meyer, PS, Perkins, DO, Losardo, D, and Lieberman, JA. "The effects of antipsychotic medications on emotion perception in patients with chronic schizophrenia in the CATIE trial." Schizophrenia Research 115, no. 1 (November 2009): 17-23. Full Text
  - Pinheiro, AP, Keefe, RSE, Skelly, T, Olarte, M, Leviel, K, Lange, LA, Lange, EM, Stroup, TS, Lieberman, J, and Sullivan, PF. "Erratum: Rates of depressive and anxiety disorders in a residential mother-infant unit for unsettled infants (Australian and New Zealand Journal of Psychiatry (2007) 41 (836-842))." Australian and New Zealand Journal of Psychiatry 43, no. 11 (November 1, 2009): 1087-null. Full Text
  - Keefe, RSE, Seidman, LJ, Christensen, BK, Hamer, RM, Sharma, T, Sitskoorn, MM, Lewine, RRJ, Yurgelun-Todd, DA, Gur, RC, Tohen, M, Tollefson, GD, Sanger, TM, and Lieberman, JA. "Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: A randomized, double-blind trial of olanzapine versus low doses of haloperidol (American Journal of Psychiatry (2004) 161, (985-995))." American Journal of Psychiatry 166, no. 8 (September 21, 2009): 942-null.
  - Lipkovich, IA, Deberdt, W, Csernansky, JG, Sabbe, B, Keefe, RS, and Kollack-Walker, S. "Relationships among neurocognition, symptoms and functioning in patients with schizophrenia: a path-analytic approach for associations at baseline and following 24 weeks of antipsychotic drug therapy." Bmc Psychiatry 9 (July 14, 2009): 44-null. Full Text
  - Marx, CE, Keefe, RSE, Buchanan, RW, Hamer, RM, Kilts, JD, Bradford, DW, Strauss, JL, Naylor, JC, Payne, VM, Lieberman, JA, Savitz, AJ, Leimone, LA, Dunn, L, Porcu, P, Morrow, AL, and Shampine, LJ. "Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 34, no. 8 (July 2009): 1885-1903. Full Text
  - Need, AC, Keefe, RSE, Ge, D, Grossman, I, Dickson, S, McEvoy, JP, and Goldstein, DB. "Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis." European Journal of Human Genetics : Ejhg 17, no. 7 (July 2009): 946-957. Full Text
  - Harvey, PD, Keefe, RSE, Patterson, TL, Heaton, RK, and Bowie, CR. "Abbreviated neuropsychological assessment in schizophrenia: prediction of different aspects of outcome." Journal of Clinical and Experimental Neuropsychology 31, no. 4 (May 2009): 462-471. Full Text
  - Tiller, J, D'Souza, DC, Keefe, RSE, Kane, JM, Patkar, AA, and Youakim, JM. "Effects of Adjunctive Armodafinil on Patients with Schizophrenia." NEUROLOGY 72, no. 11 (March 17, 2009): A336-A336. Link to Item
  - Need, AC, Ge, D, Weale, ME, Maia, J, Feng, S, Heinzen, EL, Shianna, KV, Yoon, W, Kasperaviciūte, D, Gennarelli, M, Strittmatter, WJ, Bonvicini, C, Rossi, G, Jayathilake, K, Cola, PA, McEvoy, JP, Keefe, RSE, Fisher, EMC, St Jean, PL, Giegling, I, Hartmann, AM, Möller, H-J, Ruppert, A, Fraser, G, Crombie, C, Middleton, LT, St Clair, D, Roses, AD, Muglia, P, Francks, C, Rujescu, D, Meltzer, HY, and Goldstein, DB. "A genome-wide investigation of SNPs and CNVs in schizophrenia." Plos Genetics 5, no. 2 (February 6, 2009): e1000373-null. Full Text
  - Kern, RS, Green, MF, Nuechterlein, KH, and Keefe, RSE. "Commentary on O'Halloran et al." Schizophrenia Research 107, no. 2-3 (February 1, 2009): 327-329. (Letter) Full Text
  - Davidson, M, Galderisi, S, Weiser, M, Werbeloff, N, Fleischhacker, WW, Keefe, RS, Boter, H, Keet, IPM, Prelipceanu, D, Rybakowski, JK, Libiger, J, Hummer, M, Dollfus, S, López-Ibor, JJ, Hranov, LG, Gaebel, W, Peuskens, J, Lindefors, N, Riecher-Rössler, A, and Kahn, RS. "Cognitive effects of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: A randomized, open-label clinical trial (EUFEST)." American Journal of Psychiatry 166, no. 6 (2009): 675-682. Full Text
  - Keefe, RSE, and Kraus, MS. "Measuring memory-prediction errors and their consequences in youth at risk for schizophrenia." Annals of the Academy of Medicine Singapore 38, no. 5 (2009): 414-419.
  - Kern, RS, Green, MF, Nuechterlein, KH, and Keefe, RSE. "Commentary on O'Halloran et al." Schizophrenia Research 107, no. 2-3 (2009): 327-329. Full Text
  - Kleinman, L, Lieberman, J, Dube, S, Mohs, R, Zhao, Y, Kinon, B, Carpenter, W, Harvey, PD, Green, MF, Keefe, RSE, Frank, L, Bowman, L, and Revicki, DA. "Development and psychometric performance of the schizophrenia objective functioning instrument: An interviewer administered measure of function." Schizophrenia Research 107, no. 2-3 (2009): 275-285. Full Text
  - Kraus, MS, Keefe, RSE, and Krishnan, RKR. "Memory-prediction errors and their consequences in schizophrenia." Neuropsychology Review 19, no. 3 (2009): 336-352. Full Text
  - Krishnan, RR, Keefe, R, and Kraus, M. "Schizophrenia is a disorder of higher order hierarchical processing." Medical Hypotheses 72, no. 6 (2009): 740-744. Full Text
  - Lim, C, Chong, S-A, and Keefe, RSE. "Psychosocial factors in the neurobiology of schizophrenia: A selective review." Annals of the Academy of Medicine Singapore 38, no. 5 (2009): 402-407.
  - Pinheiro, AP, Keefe, RSE, Skelly, T, Olarte, M, Leviel, K, Lange, LA, Lange, EM, Stroup, TS, Lieberman, J, and Sullivan, PF. "AKT1 and neurocognition in schizophrenia (vol 41, pg 169, 2007)." AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 43, no. 10 (2009): 983-983. Link to Item
  - Sim, K, Yang, GL, Loh, D, Poon, LY, Sitoh, YY, Verma, S, Keefe, R, Collinson, S, Chong, SA, Heckers, S, Nowinski, W, and Pantelis, C. "White matter abnormalities and neurocognitive deficits associated with the passivity phenomenon in schizophrenia: A diffusion tensor imaging study." Psychiatry Research - Neuroimaging 172, no. 2 (2009): 121-127. Full Text
  - Stroup, TS, Lieberman, JA, McEvoy, JP, Davis, SM, Swartz, MS, Keefe, RSE, Miller, AL, Rosenheck, RA, Hsiao, JK, and CATIE Investigators, . "Results of phase 3 of the CATIE schizophrenia trial." Schizophrenia Research 107, no. 1 (January 2009): 1-12. Full Text
  - Targum, SD, and Keefe, RSE. "Cognition and schizophrenia: is there a role for cognitive assessments in diagnosis and treatment?." Psychiatry (Edgmont (Pa. : Township)) 5, no. 12 (December 2008): 55-59.
  - Hawkins, KA, Keefe, RSE, Christensen, BK, Addington, J, Woods, SW, Callahan, J, Zipursky, RB, Perkins, DO, Tohen, M, Breier, A, and McGlashan, TH. "Neuropsychological course in the prodrome and first episode of psychosis: findings from the PRIME North America Double Blind Treatment Study." Schizophrenia Research 105, no. 1-3 (October 2008): 1-9. Full Text
  - Miller, DD, Caroff, SN, Davis, SM, Rosenheck, RA, McEvoy, JP, Saltz, BL, Riggio, S, Chakos, MH, Swartz, MS, Keefe, RSE, Stroup, TS, Lieberman, JA, and Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators, . "Extrapyramidal side-effects of antipsychotics in a randomised trial." The British Journal of Psychiatry : the Journal of Mental Science 193, no. 4 (October 2008): 279-288. Full Text
  - Mohamed, S, Rosenheck, R, Swartz, M, Stroup, S, Lieberman, JA, and Keefe, RSE. "Relationship of cognition and psychopathology to functional impairment in schizophrenia." The American Journal of Psychiatry 165, no. 8 (August 2008): 978-987. Full Text
  - Keefe, RSE, and Harvey, PD. "Implementation considerations for multisite clinical trials with cognitive neuroscience tasks." Schizophrenia Bulletin 34, no. 4 (July 2008): 656-663. (Review) Full Text
  - Keefe, RSE, Malhotra, AK, Meltzer, HY, Kane, JM, Buchanan, RW, Murthy, A, Sovel, M, Li, C, and Goldman, R. "Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 33, no. 6 (May 2008): 1217-1228. Full Text
  - Lieberman, JA, Drake, RE, Sederer, LI, Belger, A, Keefe, R, Perkins, D, and Stroup, S. "Science and recovery in schizophrenia." Psychiatr Serv 59, no. 5 (May 2008): 487-496. (Review) Full Text Link to Item
  - Swartz, MS, Stroup, TS, McEvoy, JP, Davis, SM, Rosenheck, RA, Keefe, RSE, Hsiao, JK, and Lieberman, JA. "What CATIE found: results from the schizophrenia trial." Psychiatric Services (Washington, D.C.) 59, no. 5 (May 2008): 500-506. Full Text
  - Resnick, SG, Rosenheck, RA, Canive, JM, De Souza, C, Stroup, TS, McEvoy, J, Davis, S, Keefe, RSE, Swartz, M, and Lieberman, J. "Employment outcomes in a randomized trial of second-generation antipsychotics and perphenazine in the treatment of individuals with schizophrenia." The Journal of Behavioral Health Services & Research 35, no. 2 (April 2008): 215-225. Full Text
  - Hill, SK, Sweeney, JA, Hamer, RM, Keefe, RSE, Perkins, DO, Gu, H, McEvoy, JP, and Lieberman, JA. "Efficiency of the CATIE and BACS neuropsychological batteries in assessing cognitive effects of antipsychotic treatments in schizophrenia." Journal of the International Neuropsychological Society : Jins 14, no. 2 (March 2008): 209-221. Full Text
  - Green, MF, Nuechterlein, KH, Kern, RS, Baade, LE, Fenton, WS, Gold, JM, Keefe, RSE, Mesholam-Gately, R, Seidman, LJ, Stover, E, and Marder, SR. "Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study." The American Journal of Psychiatry 165, no. 2 (February 2008): 221-228. Full Text
  - Keefe, RSE. "Should cognitive impairment be included in the diagnostic criteria for schizophrenia?." World Psychiatry : Official Journal of the World Psychiatric Association (Wpa) 7, no. 1 (February 2008): 22-28. Full Text
  - Kern, RS, Nuechterlein, KH, Green, MF, Baade, LE, Fenton, WS, Gold, JM, Keefe, RSE, Mesholam-Gately, R, Mintz, J, Seidman, LJ, Stover, E, and Marder, SR. "The MATRICS Consensus Cognitive Battery, part 2: co-norming and standardization." The American Journal of Psychiatry 165, no. 2 (February 2008): 214-220. Full Text
  - Nuechterlein, KH, Green, MF, Kern, RS, Baade, LE, Barch, DM, Cohen, JD, Essock, S, Fenton, WS, Frese, FJ, Gold, JM, Goldberg, T, Heaton, RK, Keefe, RSE, Kraemer, H, Mesholam-Gately, R, Seidman, LJ, Stover, E, Weinberger, DR, Young, AS, Zalcman, S, and Marder, SR. "The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity." The American Journal of Psychiatry 165, no. 2 (February 2008): 203-213. Full Text
  - Crowley, JJ, Keefe, RSE, Perkins, DO, Stroup, TS, Lieberman, JA, and Sullivan, PF. "The neuregulin 1 promoter polymorphism rs6994992 is not associated with chronic schizophrenia or neurocognition." American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 147, no. 7 (2008): 1298-1300. Full Text
  - Keefe, RSE, Harvey, PD, Goldberg, TE, Gold, JM, Walker, TM, Kennel, C, and Hawkins, K. "Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS)." Schizophrenia Research 102, no. 1-3 (2008): 108-115. Full Text
  - Goff, DC, Keefe, R, Citrome, L, Davy, K, Krystal, JH, Large, C, Thompson, TR, Volavka, J, and Webster, EL. "Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials." Journal of Clinical Psychopharmacology 27, no. 6 (December 2007): 582-589. Full Text
  - Keefe, RSE, Sweeney, JA, Gu, H, Hamer, RM, Perkins, DO, McEvoy, JP, and Lieberman, JA. "Dr. Keefe and colleagues reply." American Journal of Psychiatry 164, no. 12 (December 1, 2007): 1911-1912. (Letter) Full Text
  - Keefe, RSE, Sweeney, JA, Gu, H, Hamer, RM, Perkins, DO, McEvoy, JP, and Lieberman, JA. "Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison." The American Journal of Psychiatry 164, no. 7 (July 2007): 1061-1071. Full Text
  - Keefe, RSE, and Fenton, WS. "How should DSM-V criteria for schizophrenia include cognitive impairment?." Schizophrenia Bulletin 33, no. 4 (July 2007): 912-920. (Review) Full Text
  - Keefe, RSE, Bilder, RM, Davis, SM, Harvey, PD, Palmer, BW, Gold, JM, Meltzer, HY, Green, MF, Capuano, G, Stroup, TS, McEvoy, JP, Swartz, MS, Rosenheck, RA, Perkins, DO, Davis, CE, Hsiao, JK, Lieberman, JA, CATIE Investigators, , and Neurocognitive Working Group, . "Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial." Archives of General Psychiatry 64, no. 6 (June 2007): 633-647. Full Text
  - Rosenheck, R, Stroup, TS, Swartz, M, McEvoy, J, Davis, SM, Keefe, RSE, Hsiao, JK, and Lieberman, J. "Cost-effectiveness of schizophrenia pharmacotherapy - Reply." AMERICAN JOURNAL OF PSYCHIATRY 164, no. 4 (April 2007): 678-680. Full Text Link to Item
  - Rosenheck, R, Swartz, M, McEvoy, J, Stroup, TS, Davis, S, Keefe, RS, Hsiao, J, and Lieberman, J. "Second-generation antipsychotics: reviewing the cost-effectiveness component of the CATIE trial." Expert Review of Pharmacoeconomics & Outcomes Research 7, no. 2 (April 2007): 103-111. Full Text
  - Sullivan, PF, Keefe, RSE, Lange, LA, Lange, EM, Stroup, TS, Lieberman, J, and Maness, PF. "NCAM1 and neurocognition in schizophrenia." Biological Psychiatry 61, no. 7 (April 2007): 902-910. Full Text
  - Stroup, TS, Lieberman, JA, McEvoy, JP, Swartz, MS, Davis, SM, Capuano, GA, Rosenheck, RA, Keefe, RSE, Miller, AL, Belz, I, Hsiao, JK, and CATIE Investigators, . "Effectiveness of olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia after discontinuing perphenazine: a CATIE study." The American Journal of Psychiatry 164, no. 3 (March 2007): 415-427. Full Text
  - Swartz, MS, Perkins, DO, Stroup, TS, Davis, SM, Capuano, G, Rosenheck, RA, Reimherr, F, McGee, MF, Keefe, RSE, McEvoy, JP, Hsiao, JK, Lieberman, JA, and CATIE Investigators, . "Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study." The American Journal of Psychiatry 164, no. 3 (March 2007): 428-436. Full Text
  - Bralet, M-C, Falissard, B, Neveu, X, Lucas-Ross, M, Eskenazi, A-M, and Keefe, RSE. "Validation of the French version of the BACS (the brief assessment of cognition in schizophrenia) among 50 French schizophrenic patients." European Psychiatry 22, no. 6 (2007): 365-370. Full Text
  - Kaneda, Y, Sumiyoshi, T, Keefe, R, Ishimoto, Y, Numata, S, and Ohmori, T. "Brief Assessment of Cognition in Schizophrenia: Validation of the Japanese version." Psychiatry and Clinical Neurosciences 61, no. 6 (2007): 602-609. Full Text
  - Keefe, RSE. "Cognitive deficits in patients with schizophrenia: effects and treatment." The Journal of Clinical Psychiatry 68 Suppl 14 (January 2007): 8-13. (Review)
  - Kraus, MS, and Keefe, RSE. "Cognition as an outcome measure in schizophrenia." British Journal of Psychiatry 191, no. SUPPL. 50 (2007): s46-s51. Full Text
  - Pandina, GJ, Bilder, R, Harvey, PD, Keefe, RSE, Aman, MG, and Gharabawi, G. "Risperidone and Cognitive Function in Children With Disruptive Behavior Disorders." Biological Psychiatry 62, no. 3 (2007): 226-234. Full Text
  - Pinheiro, AP, Keefe, RSE, Skelly, T, Olarte, M, Leviel, K, Lange, LA, Lange, EM, Stroup, TS, Lieberman, J, and Sullivan, PF. "AKT1 and neurocognition in schizophrenia." Australian and New Zealand Journal of Psychiatry 41, no. 2 (2007): 169-177. Full Text
  - Rosenheck, R, Stroup, TS, Swartz, M, McEvoy, J, Davis, SM, Keefe, RSE, Hsiao, JK, and Lieberman, J. "Dr. Rosenheck and colleagues reply [2]." American Journal of Psychiatry 164, no. 4 (January 1, 2007): 678-680. (Letter) Full Text
  - Keefe, RSE, Perkins, DO, Gu, H, Zipursky, RB, Christensen, BK, and Lieberman, JA. "A longitudinal study of neurocognitive function in individuals at-risk for psychosis." Schizophrenia Research 88, no. 1-3 (December 2006): 26-35. Full Text
  - Rosenheck, RA, Leslie, DL, Sindelar, J, Miller, EA, Lin, H, Stroup, TS, McEvoy, J, Davis, SM, Keefe, RSE, Swartz, M, Perkins, DO, Hsiao, JK, Lieberman, J, and CATIE Study Investigators, . "Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia." The American Journal of Psychiatry 163, no. 12 (December 2006): 2080-2089. Full Text
  - McEvoy, JP, Johnson, J, Perkins, D, Lieberman, JA, Hamer, RM, Keefe, RSE, Tohen, M, Glick, ID, and Sharma, T. "Insight in first-episode psychosis." Psychological Medicine 36, no. 10 (October 2006): 1385-1393. Full Text
  - Keefe, RSE, Bilder, RM, Harvey, PD, Davis, SM, Palmer, BW, Gold, JM, Meltzer, HY, Green, MF, Miller, DD, Canive, JM, Adler, LW, Manschreck, TC, Swartz, M, Rosenheck, R, Perkins, DO, Walker, TM, Stroup, TS, McEvoy, JP, and Lieberman, JA. "Baseline neurocognitive deficits in the CATIE schizophrenia trial." Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 31, no. 9 (September 2006): 2033-2046. Full Text
  - Chakos, MH, Glick, ID, Miller, AL, Hamner, MB, Miller, DD, Patel, JK, Tapp, A, Keefe, RSE, and Rosenheck, RA. "Baseline use of concomitant psychotropic medications to treat schizophrenia in the CATIE trial." Psychiatric Services (Washington, D.C.) 57, no. 8 (August 2006): 1094-1101. Full Text
  - Chwastiak, LA, Rosenheck, RA, McEvoy, JP, Keefe, RS, Swartz, MS, and Lieberman, JA. "Interrelationships of psychiatric symptom severity, medical comorbidity, and functioning in schizophrenia." Psychiatric Services (Washington, D.C.) 57, no. 8 (August 2006): 1102-1109. Full Text
  - Keefe, RSE. "Missing the sweet spot disengagement in schizophrenia." Psychiatry (Edgmont (Pa. : Township)) 3, no. 7 (July 2006): 36-41.
  - McEvoy, JP, Lieberman, JA, Stroup, TS, Davis, SM, Meltzer, HY, Rosenheck, RA, Swartz, MS, Perkins, DO, Keefe, RSE, Davis, CE, Severe, J, Hsiao, JK, and CATIE Investigators, . "Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment." The American Journal of Psychiatry 163, no. 4 (April 2006): 600-610. Full Text
  - Stroup, TS, Lieberman, JA, McEvoy, JP, Swartz, MS, Davis, SM, Rosenheck, RA, Perkins, DO, Keefe, RSE, Davis, CE, Severe, J, Hsiao, JK, and CATIE Investigators, . "Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic." The American Journal of Psychiatry 163, no. 4 (April 2006): 611-622. Full Text
  - Perkins, DO, Johnson, JL, Hamer, RM, Zipursky, RB, Keefe, RS, Centorrhino, F, Green, AI, Glick, IB, Kahn, RS, Sharma, T, Tohen, M, McEvoy, JP, Weiden, PJ, Lieberman, JA, and HGDH Research Group, . "Predictors of antipsychotic medication adherence in patients recovering from a first psychotic episode." Schizophrenia Research 83, no. 1 (March 9, 2006): 53-63. Full Text
  - Keefe, RSE, Poe, M, Walker, TM, Kang, JW, and Harvey, PD. "The Schizophrenia Cognition Rating Scale: an interview-based assessment and its relationship to cognition, real-world functioning, and functional capacity." The American Journal of Psychiatry 163, no. 3 (March 2006): 426-432. Full Text
  - LIEBERMAN, JEFFREYA, STROUP, TSCOTT, McEVOY, JOSEPHP, SWARTZ, MARVINS, ROSENHECK, ROBERTA, PERKINS, DIANAO, KEEFE, RICHARDSE, DAVIS, SONIAM, DAVIS, CLARENCEE, HSIAO, JOHN, SEVERE, JOANNE, LEBOWITZ, BARRYD, and the CATIE Investigators, . "Dr. Lieberman and Colleagues Reply." American Journal of Psychiatry 163, no. 3 (March 2006). Full Text
  - Lieberman, JA, Stroup, TS, McEvoy, JP, Swartz, MS, Rosenheck, RA, Perkins, DO, Keefe, RSE, Davis, SM, Davis, CE, Hsiao, J, Severe, J, and Lebowitz, BD. "Dr. Lieberman and Colleagues reply [17]." American Journal of Psychiatry 163, no. 3 (March 1, 2006): 555-556. (Letter)
  - Rosenheck, R, Leslie, D, Keefe, R, McEvoy, J, Swartz, M, Perkins, D, Stroup, S, Hsiao, JK, Lieberman, J, and CATIE Study Investigators Group, . "Barriers to employment for people with schizophrenia." The American Journal of Psychiatry 163, no. 3 (March 2006): 411-417. Full Text
  - Keefe, RSE, Poe, M, Walker, TM, and Harvey, PD. "The relationship of the Brief Assessment of Cognition in Schizophrenia (BACS) to functional capacity and real-world functional outcome." Journal of Clinical and Experimental Neuropsychology 28, no. 2 (2006): 260-269. Full Text
  - Keefe, RSE, Seidman, LJ, Christensen, BK, Hamer, RM, Sharma, T, Sitskoorn, MM, Rock, SL, Woolson, S, Tohen, M, Tollefson, GD, Sanger, TM, Lieberman, JA, and HGDH Research Group, . "Long-term neurocognitive effects of olanzapine or low-dose haloperidol in first-episode psychosis." Biological Psychiatry 59, no. 2 (January 2006): 97-105. Full Text
  - Keefe, RSE, Young, CA, Rock, SL, Purdon, SE, Gold, JM, Breier, A, and HGGN Study Group, . "One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia." Schizophrenia Research 81, no. 1 (January 2006): 1-15. Full Text
  - Woodward, TS, Menon, M, Hu, X, and Keefe, RSE. "Optimization of a multinomial model for investigating hallucinations and delusions with source monitoring." Schizophrenia Research 85, no. 1-3 (2006): 106-112. Full Text
  - Miller, DD, McEvoy, JP, Davis, SM, Caroff, SN, Saltz, BL, Chakos, MH, Swartz, MS, Keefe, RSE, Rosenheck, RA, Stroup, TS, and Lieberman, JA. "Clinical correlates of tardive dyskinesia in schizophrenia: baseline data from the CATIE schizophrenia trial." Schizophrenia Research 80, no. 1 (December 2005): 33-43. Full Text
  - Rosenheck, R, Stroup, S, Keefe, RSE, McEvoy, J, Swartz, M, Perkins, D, Hsiao, J, Shumway, M, and Lieberman, J. "Measuring outcome priorities and preferences in people with schizophrenia." The British Journal of Psychiatry : the Journal of Mental Science 187 (December 2005): 529-536. Full Text
  - Stroup, S, Appelbaum, P, Swartz, M, Patel, M, Davis, S, Jeste, D, Kim, S, Keefe, R, Manschreck, T, McEvoy, J, and Lieberman, J. "Decision-making capacity for research participation among individuals in the CATIE schizophrenia trial." Schizophrenia Research 80, no. 1 (December 2005): 1-8. Full Text
  - Strakowski, SM, Johnson, JL, Delbello, MP, Hamer, RM, Green, AI, Tohen, M, Lieberman, JA, Glick, I, Patel, JK, and HGDH Research Group, . "Quality of life during treatment with haloperidol or olanzapine in the year following a first psychotic episode." Schizophrenia Research 78, no. 2-3 (October 2005): 161-169. Full Text
  - Lieberman, JA, Stroup, TS, McEvoy, JP, Swartz, MS, Rosenheck, RA, Perkins, DO, Keefe, RSE, Davis, SM, Davis, CE, Lebowitz, BD, Severe, J, Hsiao, JK, and Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators, . "Effectiveness of antipsychotic drugs in patients with chronic schizophrenia." The New England Journal of Medicine 353, no. 12 (September 19, 2005): 1209-1223. Full Text
  - Lieberman, JA, Tollefson, GD, Charles, C, Zipursky, R, Sharma, T, Kahn, RS, Keefe, RSE, Green, AI, Gur, RE, McEvoy, J, Perkins, D, Hamer, RM, Gu, H, Tohen, M, and HGDH Study Group, . "Antipsychotic drug effects on brain morphology in first-episode psychosis." Archives of General Psychiatry 62, no. 4 (April 2005): 361-370. Full Text
  - Keefe, RSE, Eesley, CE, and Poe, MP. "Defining a cognitive function decrement in schizophrenia." Biological Psychiatry 57, no. 6 (March 2005): 688-691. Full Text
  - Buchanan, RW, Davis, M, Goff, D, Green, MF, Keefe, RSE, Leon, AC, Nuechterlein, KH, Laughren, T, Levin, R, Stover, E, Fenton, W, and Marder, SR. "A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia." Schizophrenia Bulletin 31, no. 1 (January 2005): 5-19. Full Text
  - Fortuny, LAI, Garolera, M, Romo, DH, Feldman, E, Barillas, HF, Keefe, R, Lemaêtre, MJ, Martín, AO, Mirsky, A, Monguió, I, Morote, G, Parchment, S, Parchment, LJ, Pena, ED, Politis, DG, Sedó, MA, Taussik, I, Valdivia, F, Valdivia, LED, and Maestre, KV. "Research with Spanish-speaking populations in the United States: Lost in the translation - A commentary and a plea." Journal of Clinical and Experimental Neuropsychology 27, no. 5 (2005): 555-564. Full Text
  - Meyer, JM, Nasrallah, HA, McEvoy, JP, Goff, DC, Davis, SM, Chakos, M, Patel, JK, Keefe, RSE, Stroup, TS, and Lieberman, JA. "The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Schizophrenia Trial: Clinical comparison of subgroups with and without the metabolic syndrome." Schizophrenia Research 80, no. 1 (2005): 9-18. Full Text
  - Narendran, R, Frankle, WG, Keefe, R, Gil, R, Martinez, D, Slifstein, M, Kegeles, LS, Talbot, PS, Huang, Y, Hwang, D-R, Khenissi, L, Cooper, TB, Laruelle, M, and Abi-Dargham, A. "Altered prefrontal dopaminergic function in chronic recreational ketamine users." American Journal of Psychiatry 162, no. 12 (2005): 2352-2359. Full Text
  - Green, MF, Nuechterlein, KH, Gold, JM, Barch, DM, Cohen, J, Essock, S, Fenton, WS, Frese, F, Goldberg, TE, Heaton, RK, Keefe, RSE, Kern, RS, Kraemer, H, Stover, E, Weinberger, DR, Zalcman, S, and Marder, SR. "Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria." Biological Psychiatry 56, no. 5 (September 2004): 301-307. (Review) Full Text
  - Keefe, RSE, Goldberg, TE, Harvey, PD, Gold, JM, Poe, MP, and Coughenour, L. "The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery." Schizophrenia Research 68, no. 2-3 (June 2004): 283-297. Full Text
  - Keefe, RSE, Seidman, LJ, Christensen, BK, Hamer, RM, Sharma, T, Sitskoorn, MM, Lewine, RRJ, Yurgelun-Todd, DA, Gur, RC, Tohen, M, Tollefson, GD, Sanger, TM, and Lieberman, JA. "Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: a randomized, double-blind trial of olanzapine versus low doses of haloperidol." The American Journal of Psychiatry 161, no. 6 (June 2004): 985-995. Full Text
  - Harvey, PD, Green, MF, Keefe, RSE, and Velligan, DI. "Cognitive functioning in schizophrenia: A consensus statement on its role in the definition and evaluation of effective treatments for the illness." Journal of Clinical Psychiatry 65, no. 3 (2004): 361-372. Full Text
  - Hawkins, KA, Addington, J, Keefe, RSE, Christensen, B, Perkins, DO, Zipurksy, R, Woods, SW, Miller, TJ, Marquez, E, Breier, A, and McGlashan, TH. "Neuropsychological status of subjects at high risk for a first episode of psychosis." Schizophrenia Research 67, no. 2-3 (2004): 115-122. Full Text
  - KEEFE, R. "Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis : a randomized. double-blind trial of olanzapine versus low doses of haloperidol." Am J Psychiatry 161 (2004): 985-995. Full Text
  - Keefe, RSE, Poe, MP, McEvoy, JP, and Vaughan, A. "Source monitoring improvement in patients with schizophrenia receiving antipsychotic medications." Psychopharmacology (Berl) 169, no. 3-4 (September 2003): 383-389. Full Text Link to Item
  - Keefe, RSE, Mohs, RC, Bilder, RM, Harvey, PD, Green, MF, Meltzer, HY, Gold, JM, and Sano, M. "Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale." Schizophrenia Bulletin 29, no. 1 (January 2003): 45-55. Full Text
  - Keefe, RSE, Arnold, MC, Bayen, UJ, McEvoy, JP, and Wilson, WH. "Source-monitoring deficits for self-generated stimuli in schizophrenia: multinomial modeling of data from three sources." Schizophr Res 57, no. 1 (September 1, 2002): 51-67. Link to Item
  - Conway, CR, Bollini, AM, Graham, BG, Keefe, RSE, Schiffman, SS, and McEvoy, JP. "Sensory acuity and reasoning in delusional disorder." Compr Psychiatry 43, no. 3 (May 2002): 175-178. Link to Item
  - Keefe, RSE. "Evaluation of cognitive dysfunctions in schizophrenia." Encephale 28, no. 5 II (2002): 11-13.
  - Harvey, PD, and Keefe, RSE. "Studies of cognitive change in patients with schizophrenia following novel antipsychotic treatment." American Journal of Psychiatry 158, no. 2 (2001): 176-184. Full Text
  - Bollini, AM, Arnold, MC, and Keefe, RSE. "Test-retest reliability of the Dot Test of Visuospatial Working Memory in patients with schizophrenia and controls." Schizophrenia Research 45, no. 1-2 (2000): 169-173. Full Text
  - Roitman, SEL, Mitropoulou, V, Keefe, RSE, Silverman, JM, Serby, M, Harvey, PD, Reynolds, DA, Mohs, RC, and Siever, LJ. "Visuospatial working memory in schizotypal personality disorder patients." Schizophrenia Research 41, no. 3 (2000): 447-455. Full Text
  - Keefe, RS, Silva, SG, Perkins, DO, and Lieberman, JA. "The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: a review and meta-analysis." Schizophrenia Bulletin 25, no. 2 (January 1999): 201-222. Full Text
  - Keefe, RSE, Arnold, MC, Bayen, UJ, and Harvey, PD. "Source monitoring deficits in patients with schizophrenia; a multinomial modelling analysis." Psychological Medicine 29, no. 4 (1999): 903-914. Full Text
  - Keefe, RSE, Bollini, AM, and Silva, SG. "Do novel antipsychotics improve cognition? A report of a meta-analysis." Psychiatric Annals 29, no. 11 (January 1, 1999): 623-629. Full Text
  - Davis, KL, Buchsbaum, MS, Shihabuddin, L, Spiegel-Cohen, J, Metzger, M, Frecska, E, Keefe, RS, and Powchik, P. "Ventricular enlargement in poor-outcome schizophrenia." Biological Psychiatry 43, no. 11 (1998): 783-793. Full Text
  - Keefe, RSE, Courtney, M, Bayan, UJ, Harvey, PD, and McEvoy, JM. "Does autonoetic agnosia underlie specific psychotic symptoms in schizophrenia?." Schizophrenia Research 29, no. 1-2 (January 1998): 36-36. Full Text
  - Keefe, RS, Silverman, JM, Mohs, RC, Siever, LJ, Harvey, PD, Friedman, L, Roitman, SE, DuPre, RL, Smith, CJ, Schmeidler, J, and Davis, KL. "Eye tracking, attention, and schizotypal symptoms in nonpsychotic relatives of patients with schizophrenia." Archives of General Psychiatry 54, no. 2 (February 1997): 169-176. Full Text
  - Harvey, PD, and Keefe, RSE. "Cognitive impairment in schizophrenia and implications of atypical neuroleptic treatment." Cns Spectrums 2, no. 8 (January 1, 1997): 41-55. (Review) Full Text
  - Harvey, PD, and Keefe, RSE. "Cognitive impairment in schizophrenia and implications of atypical neuroleptic treatment." Cns Spectrums 2, no. 8 (1997): 41-55.
  - Keefe, RSE, Courtney, M, and McEvoy, JM. "Self-monitoring deficits in schizophrenia: Autonoetic agnosia." Schizophrenia Research 24, no. 1-2 (January 1997): 110-110. Full Text
  - Keefe, RSE, Lees-Roitman, SE, and Dupre, RL. "Performance of patients with schizophrenia on a pen and paper visuospatial working memory task with short delay." Schizophrenia Research 26, no. 1 (1997): 9-14. Full Text
  - Roitman, SEL, Cornblatt, BA, Bergman, A, Obuchowski, M, Mitropoulou, V, Keefe, RSE, Silverman, JM, and Siever, LJ. "Attentional functioning in schizotypal personality disorder." American Journal of Psychiatry 154, no. 5 (1997): 655-660.
  - Roitman, SEL, Keefe, RSE, Harvey, PD, Siever, LJ, and Mohs, RC. "Attentional and eye tracking deficits correlate with negative symptoms in schizophrenia." Schizophrenia Research 26, no. 2-3 (1997): 139-146. Full Text
  - Vocisano, C, Klein, DN, and Keefe, RSE. "Lifetime comorbidity, lifetime history of psychosis and suicide attempts, and current symptoms of patients with deteriorated affective disorder." Psychiatry Research 73, no. 1-2 (1997): 33-45. Full Text
  - Keefe, RSE, and Cornblatt, BA. "The neuropsychology of schizophrenia - David,AS, Cutting,JC." CONTEMPORARY PSYCHOLOGY 41, no. 9 (September 1996): 900-902. Link to Item
  - Harvey, PD, Keefe, RSE, Mitroupolou, V, DuPre, R, Roitman, SL, Mohs, RC, and Siever, LJ. "Information-processing markers of vulnerability to schizophrenia: Performance of patients with schizotypal and nonschizotypal personality disorders." Psychiatry Research 60, no. 1 (February 28, 1996): 49-56. Full Text
  - Epstein, JI, Keefe, RSE, Roitman, SL, Harvey, PD, and Mohs, RC. "Impact of neuroleptic medications on continuous performance test measures in schizophrenia." Biological Psychiatry 39, no. 10 (1996): 902-905. Full Text
  - Harvey, PD, Davidson, M, White, L, Keefe, RSE, Hirschowitz, J, Mohs, RC, and Davis, KL. "Empirical evaluation of the factorial structure of clinical symptoms in schizophrenia: Effects of typical neuroleptics on the brief psychiatric rating scale." Biological Psychiatry 40, no. 8 (1996): 755-760. Full Text
  - Jr, BVS, Trestman, RL, O'Flaithbheartaigh, S, Mitropoulou, V, Amin, F, Kirrane, R, Silverman, J, Schmeidler, J, Keefe, RSE, and Siever, LJ. "D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder." Schizophrenia Research 20, no. 1-2 (1996): 29-32. Full Text
  - Keefe, RSE, Frescka, E, Apter, SH, Davidson, M, Macaluso, JM, Hirschowitz, J, and Davis, KL. "Clinical characteristics of Kraepelinian schizophrenia: Replication and extension of previous findings." American Journal of Psychiatry 153, no. 6 (1996): 806-811.
  - Vocisano, C, Klein, DN, Keefe, RSE, Dienst, ER, and Kincaid, MM. "Demographics, family history, premorbid functioning, developmental characteristics, and course of patients with deteriorated affective disorder." American Journal of Psychiatry 153, no. 2 (1996): 248-255.
  - Trestman, RL, Keefe, RS, Mitropoulou, V, Harvey, PD, deVegvar, ML, Lees-Roitman, S, Davidson, M, Aronson, A, Silverman, J, and Siever, LJ. "Cognitive function and biological correlates of cognitive performance in schizotypal personality disorder." Psychiatry Research 59, no. 1-2 (November 1995): 127-136. Full Text
  - Keefe, RSE, Lees Roitman, S, Dupre, RL, Harvey, PD, Davis, KL, and Mohs, RC. "The relationship between working memory deficits and other measures sensitive to prefrontal dysfunction." Schizophrenia Research 15, no. 1-2 (April 1995): 123-123. Full Text
  - Davidson, M, Harvey, PD, Powchik, P, Parrella, M, White, L, Knobler, HY, Losonczy, MF, Keefe, RS, Katz, S, and Frecska, E. "Severity of symptoms in chronically institutionalized geriatric schizophrenic patients." The American Journal of Psychiatry 152, no. 2 (February 1995): 197-207. Full Text
  - Davidson, M, and Keefe, RSE. "Cognitive impairment as a target for pharmacological treatment in schizophrenia." Schizophrenia Research 17, no. 1 (1995): 123-129. Full Text
  - Keefe, RSE, Roitman, SEL, Harvey, PD, Blum, CS, DuPre, RL, Prieto, DM, Davidson, M, and Davis, KL. "A pen-and-paper human analogue of a monkey prefrontal cortex activation task: spatial working memory in patients with schizophrenia." Schizophrenia Research 17, no. 1 (1995): 25-33. Full Text
  - Keefe, RSE. "The contribution of neuropsychology to psychiatry." American Journal of Psychiatry 152, no. 1 (1995): 6-15.
  - Yehuda, R, Keefe, RS, Harvey, PD, Levengood, RA, Gerber, DK, Geni, J, and Siever, LJ. "Learning and memory in combat veterans with posttraumatic stress disorder." The American Journal of Psychiatry 152, no. 1 (January 1995): 137-139. Full Text
  - Apter, SH, Keefe, RSE, Hirschowitz, J, Davidson, M, Macaluso, JM, Amato, R, and Davis, KL. "Longitudinal classification in schizophrenia: The relationship between kraepelinian and deficit syndrome subtypologies." Biological Psychiatry 35, no. 9 (May 1994): 695-695. Full Text
  - EPSTEIN, JI, KEEFE, RSE, ROITMAN, SEL, HARVEY, PD, DAVIDSON, M, SIEVER, LJ, and MOHS, RC. "NEUROLEPTIC EFFECTS ON CPT AND EYE TRACKING IN SCHIZOPHRENIA." BIOLOGICAL PSYCHIATRY 35, no. 9 (May 1, 1994): 674-674. Full Text Link to Item
  - Frecska, E, Losonczy, MF, Keefe, RSE, Apter, S, Davidson, M, Mohs, RC, and Davis, KL. "Age dependent change of ventricular measures in schizophrenia: Cross-sectional analysis." Biological Psychiatry 35, no. 9 (May 1994): 704-705. Full Text
  - Keefe, RSE, Blum, C, Roitman, SL, Harvey, PD, Davidson, M, Mohs, RC, and Davis, KL. "Working memory dysfunction in Kraepelinian schizophrenics." Biological Psychiatry 35, no. 9 (May 1994): 660-660. Full Text
  - Kahn, R, Harvey, PD, Davidson, M, Keefe, RSE, Apter, S, Neale, JM, Mohs, RC, and Davis, KL. "Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function." Schizophrenia Research 11, no. 3 (1994): 217-224. Full Text
  - Keefe, RSE, Silverman, JM, Roitman, SEL, Harvey, PD, Duncan, MA, Alroy, D, Siever, LJ, Davis, KL, and Mohs, RC. "Performance of nonpsychotic relatives of schizophrenic patients on cognitive tests." Psychiatry Research 53, no. 1 (1994): 1-12. Full Text
  - Siever, LJ, Friedman, L, Moskowitz, J, Mitropoulou, V, Keefe, R, Roitman, SL, Merhige, D, Trestman, R, Silverman, J, and Mohs, R. "Eye movement impairment and schizotypal psychopathology." American Journal of Psychiatry 151, no. 8 (1994): 1209-1215.
  - Siever, LJ, Kalus, OF, and Keefe, RS. "The boundaries of schizophrenia." The Psychiatric Clinics of North America 16, no. 2 (June 1993): 217-244. (Review) Full Text
  - Frecska, E, Losonczy, MF, Keefe, RSE, Silverman, JM, Davidson, M, and Davis, KL. "The characteristics of poor outcome, 'Kraepelinian' schizophrenia." European Neuropsychopharmacology 3, no. 3 (January 1, 1993): 400-null. Full Text
  - Harvey, PD, Lenzenweger, MF, Keefe, RS, Pogge, DL, Serper, MR, and Mohs, RC. "Empirical assessment of the factorial structure of clinical symptoms in schizophrenic patients: formal thought disorder." Psychiatry Research 44, no. 2 (November 1992): 141-151. Full Text
  - Davidson, M, Kahn, RS, Stern, RG, Harvey, PD, Keefe, R, Knott, P, Apter, S, Webster, L, and Davis, KL. "Measurements of plasma homovanillic acid in schizophrenic patients." Clinical Neuropharmacology 15 Suppl 1 Pt A (1992): 521A-522A.
  - Harvey, PD, Kahn, RS, Davidson, M, Mohs, RC, Keefe, RSE, and Davis, KL. "Dopaminergic correlates of attentional performance in unmedicated schizophrenic patients." Schizophrenia Research 6, no. 2 (January 1992): 136-136. Full Text
  - Keefe, RSE, Harvey, PD, Lenzenweger, MF, Davidson, M, Apter, SH, Schmeidler, J, Mohs, RC, and Davis, KL. "Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms." Psychiatry Research 44, no. 2 (1992): 153-165. Full Text
  - Keefe, RSE, Silverman, JM, Amin, F, Lees, SE, Duncan, A, Harvey, PD, Davidson, M, Siever, LJ, Mohs, RC, and Davis, KL. "Frontal functioning and plasma HVA in the relatives of schizophrenic patients." Schizophrenia Research 6, no. 2 (January 1992): 158-158. Full Text
  - Frecska, E, Losonczy, M, Keefe, RSE, Silverman, JM, Davidson, M, Harvey, P, McQueeney, RT, Lobel, D, Apter, S, and Davis, KL. "Kraepelinian schizophrenia: A replication in an independent sample." Schizophrenia Research 4, no. 3 (May 1991): 257-257. Full Text
  - Harvey, PD, Davidson, M, Mohs, RC, Keefe, RSE, Moskowitz, J, Knott, P, and Duffelmeyer, M. "Plasma HVA correlates of attentional performance in unmedicated schizophrenics." Schizophrenia Research 4, no. 3 (May 1991): 345-346. Full Text
  - CORNBLATT, BA, and KEEFE, RSE. "THE GENETICS OF MENTAL-ILLNESS - AN OVERVIEW." SOCIAL BIOLOGY 38, no. 3-4 (1991): R1-R5. Link to Item
  - Harvey, PD, Putnam, KM, Davidson, M, Kahn, RS, Powchik, P, McQueeney, R, Keefe, RSE, and Davis, KL. "Brief neuroleptic discontinuation and clinical symptoms in Kraepelinian and non-Kraepelinian chronic schizophrenic patients." Psychiatry Research 38, no. 3 (1991): 285-292. Full Text
  - Keefe, RS, Silverman, JM, Siever, LJ, and Cornblatt, BA. "Refining phenotype characterization in genetic linkage studies of schizophrenia." Social biology 38, no. 3-4 (1991): 197-218.
  - Keefe, RSE, Lobelc, DS, Mohs, RC, Silverman, JM, Harvey, PD, Davidson, M, Losonczy, MF, and Davis, KL. "Diagnostic issues in chronic schizophrenia: kraepelinian schizophrenia, undifferentiated schizophrenia, and state-independent negative symptoms." Schizophrenia Research 4, no. 2 (1991): 71-79.
  - Thaker, G, Moran, M, Cassady, S, Adami, H, Tamminga, C, Siever, LJ, Keefe, R, Bernstein, DP, Coccaro, EF, Klar, HM, Zemishlany, Z, Peterson, A, Davidson, M, Mahon, T, Horvath, T, and Mohs, R. "Normal smooth pursuit eye movements in volunteer subjects meeting schizotypal personality disorder criteria [16]." American Journal of Psychiatry 148, no. 8 (1991): 1096-1097.
  - Harvey, PD, Keefe, RSE, Moskowitz, J, Putnam, KM, Mohs, RC, and Davis, KL. "Attentional markers of vulnerability to schizophrenia: Performance of medicated and unmedicated patients and normals." Psychiatry Research 33, no. 2 (1990): 179-188. Full Text
  - Siever, LJ, Keefe, R, Bernstein, DP, Coccaro, EF, Klar, HM, Zemishlany, Z, Peterson, AE, Davidson, M, Mahon, T, Horvath, T, and Mohs, R. "Eye tracking impairment in clinically identified patients with schizotypal personality disorder." American Journal of Psychiatry 147, no. 6 (1990): 740-745.
  - Siever, LJ, Silverman, JM, Horvath, TB, Klar, H, Coccaro, E, Keefe, RSE, Pinkham, L, Rinaldi, P, Mohs, RC, and Davis, KL. "Increased morbid risk for schizophrenia-related disorders in relatives of schizotypal personality disordered patients." Archives of General Psychiatry 47, no. 7 (1990): 634-640.
  - Keefe, RSE, Mohs, RC, Losonczy, MF, Davidson, MD, Silverman, JM, Horvath, TB, and Davis, KL. "Premorbid sociosexual functioning and long-term outcome in schizophrenia." American Journal of Psychiatry 146, no. 2 (1989): 206-211.
  - Keefe, RSE, Siever, LJ, Mohs, RC, Peterson, AE, Mahon, TR, Bergman, RL, and Davis, KL. "Eye tracking, schizophrenic symptoms, and schizotypal personality disorder." European Archives of Psychiatry and Neurological Sciences 239, no. 1 (1989): 39-42. Full Text
  - Silverman, JM, Keefe, RS, Mohs, RC, and Davis, KL. "A study of the reliability of the family history method in genetic studies of Alzheimer disease." Alzheimer disease and associated disorders 3, no. 4 (1989): 218-223.
  - Keefe, RSE, Mohs, RC, Davidson, M, Losonczy, MF, Silverman, JM, Lesser, JC, Horvath, TB, and Davis, KL. "Kraepelinian schizophrenia: A subgroup of schizophrenia?." Psychopharmacology Bulletin 24, no. 1 (1988): 56-61.
  - Davidson, M, Keefe, RSE, Mohs, RC, Siever, LJ, Losonczy, MF, Horvath, TB, and Davis, KL. "L-Dopa challenge and relapse in schizophrenia." American Journal of Psychiatry 144, no. 7 (1987): 934-938.
  - Keefe, RSE, Mohs, RC, Losonczy, MF, Davidson, M, Silverman, JM, Kendler, KS, Horvath, TB, Nora, R, and Davis, KL. "Characteristics of very poor outcome schizophrenia." American Journal of Psychiatry 144, no. 7 (1987): 889-895.
  - Silverman, JM, Mohs, RC, Davidson, M, Losonczy, MF, Keefe, RSE, Breitner, JCS, Sorokin, JE, and Davis, KL. "Familial schizophrenia and treatment response." American Journal of Psychiatry 144, no. 10 (1987): 1271-1276.
- Book Sections
  - Vance, M, Pappadopulos, E, Keefe, R, and Kalali, A. "Conceptual issues in cultural adaptation and the role of culture in assessment of health-related quality of life in schizophrenia." In Beyond Assessment of Quality of Life in Schizophrenia, 53-62. January 1, 2016. Full Text
- Conference Papers
  - Brown, D, Nakagome, K, Cordes, J, Brenner, R, Gründer, G, Keefe, RSE, Riesenberg, R, Walling, DP, Daniels, K, Wang, L, McGinniss, J, and Sand, M. "Evaluation of the Efficacy, Safety, and Tolerability of BI 409306, a Novel Phosphodiesterase 9 Inhibitor, in Cognitive Impairment in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial." March 2019. Full Text
  - Eum, S, Hill, SK, Rubin, LH, Carnahan, RM, Reilly, JL, Ivleva, EI, Keedy, SK, Tamminga, CA, Pearlson, GD, Clementz, BA, Gershon, ES, Keshavan, MS, Keefe, RSE, Sweeney, JA, and Bishop, JR. "Cognitive burden of anticholinergic medications in psychotic disorders." December 2017. Full Text
  - Graham, KA, Keefe, RS, Lieberman, JA, Calikoglu, AS, Lansing, KM, and Perkins, DO. "Relationship of low vitamin D status with positive, negative and cognitive symptom domains in people with first-episode schizophrenia." October 2015. Full Text
  - Keefe, R, Mahableshwarkar, A, and Olsen, C. "P.2.f.013 Clinical evidence for improvement in cognitive dysfunction in patients with major depressive disorder (MDD) after treatment with vortioxetine." October 2013. Full Text
  - Madhoo, M, Roth, RM, Keefe, RSE, Sambunaris, A, Scheckner, B, Nielsen, J, Adeyi, B, Wu, J, and Lasser, R. "P.2.a.017 Lisdexamfetamine dimesylate augmentation effects on executive function in major depressive disorder based on depressive symptom levels." : Elsevier BV, October 2012. Full Text
  - Madhoo, M, Keefe, RSE, Roth, RM, Sambunaris, A, Wu, J, Trivedi, MH, Anderson, CS, and Lasser, R. "Efficacy and safety of lisdexamfetamine dimesylate in adults with executive dysfunction and partial or full remission of major depressive disorder." : OXFORD UNIV PRESS, June 1, 2012. Link to Item
  - Supina, D, Endicott, J, Madhoo, M, Keefe, RSE, Trivedi, M, Wu, J, Scheckner, B, and Lasser, R. "EFFECTS OF LISDEXAMFETAMINE DIMESYLATE AUGMENTATION ON FUNCTIONAL OUTCOMES IN ADULTS WITH PARTIALLY OR FULLY REMITTED MAJOR DEPRESSIVE DISORDER." June 2012. Full Text Link to Item
  - Jarskog, FF, Grove, RA, McEvoy, JP, Keefe, RSE, Lowy, MT, Horrigan, JP, and Peykamian, MA. "Randomized, Double-Blind, Placebo Controlled, Parallel Group Exploratory Study of GSK239512 for Cognitive Impairment in Stable Schizophrenia Subjects on Background Antipsychotic Therapy." April 15, 2012. Link to Item
  - Colijn, MA, Barbato, M, Keefe, RS, Perkins, DO, Woods, SW, and Addington, J. "Poster #143 AT RISK FOR PSYCHOSIS: THE ROLE OF COGNITION." April 2012. Full Text
  - Keefe, RS, Buchanan, RW, Marder, SR, Schooler, NR, Dugar, A, Zivkov, M, and Stewart, M. "Poster #199 CLINICAL TRIALS OF POTENTIAL COGNITIVE-ENHANCING DRUGS IN SCHIZOPHRENIA: WHAT HAVE WE LEARNED SO FAR?." April 2012. Full Text
  - Uchida, H, Sakurai, H, Bies, RR, Stroup, S, Keefe, RSE, Suzuki, T, Tsuboi, T, Mimura, M, Pollock, BG, and Mamo, DC. "DOPAMINE D2 RECEPTOR OCCUPANCY AND COGNITION IN SCHIZOPHRENIA: ANALYSIS OF THE CATIE DATA." April 2012. Link to Item
  - Sarkisyan, G, Gurovich, I, and Keefe, RSE. "NORMATIVE DATA FOR RUSSIAN POPULATION AND STANDARDIZATION OF THE SCALE "BRIEF ASSESSMENT OF COGNITION IN SCHIZOPHRENIA"." 2011. Link to Item
  - Kern, RS, Gold, JM, Dickinson, D, Green, MF, Nuechterlein, KH, Keefe, RSE, Marder, SR, and Sugar, CA. "COGNITIVE DYSFUNCTION AND COMMUNITY FUNCTIONING IN SCHIZOPHRENIA: RESULTS FROM THE MATRICS PSYCHOMETRIC AND STANDARDIZATION STUDY (PASS)." April 2010. Full Text Link to Item
  - Keefe, RSE, and Fenton, WS. "HOW SHOULD DSM-V CRITERIA FOR SCHIZOPHRENIA INCLUDE COGNITIVE IMPAIRMENT?." 2010. Link to Item
  - Keefe, RSE. "Increasing sensitivity of early detection of psychosis with cognitive measures." 2009. Link to Item
  - Keefe, RSE, Harvey, PD, Goldberg, TE, Gold, JM, and Walker, TM. "General and specific cognitive deficits in bipolar depression: the Brief Assessment of Cognition in Affective Disorders (BAC-A)." June 2007. Link to Item
  - Nasrallah, HA, Keefe, RSE, Davis, S, Mcevoy, J, Goff, D, Meyer, J, Stroup, TS, and Lieberman, JA. "Cognitive improvement correlates with weight gain in schizophrenia subjects receiving quetiapine but not other antipsychotics: Data from the CATIE trial." April 15, 2007. Link to Item
  - Keefe, RSE. "Measures of cognitive change in schizophrenia clinical trials." July 2006. Link to Item
  - Keefe, RSE, Hongbin, GU, Sweeney, JA, Perkins, DO, McEvoy, JP, Hamer, RM, and Lieberman, JA. "The effects of olanzapine, quetiapine, and risperidone on neurocognitive function in first-episode psychosis: A double-blind, 52-week comparison." April 15, 2006. Link to Item
  - Keefe, RSE, Gu, H, Perkins, D, Hamer, RM, and Lieberman, JA. "The effects of olanzapine, quetiapine, and risperidone on neurocognitive function in first-episode psychosis: A double-blind, 52-week comparison." January 2006. Link to Item
  - Sethuraman, G, Ahmed, S, Rock, SL, Young, CA, Marquez, EM, Purdon, SE, and Keefe, RSE. "P.2.137 Can the PANSS cognitive factor be a validsurrogate for neurocognon in schizophrenia?." : Elsevier BV, October 2004. Full Text
  - Keefe, RSE. "Treatment of cognitive deficits in first episode schizophrenia." June 2004. Link to Item
  - Keefe, RSE. "Cognition as a key to alliance, adherence, and functional outcomes." June 2004. Link to Item
  - Hawkins, KA, Addington, J, Keefe, RSE, Christensen, BK, Woods, SW, Miller, TJ, Trzaskoma, QN, Breier, A, Zipursky, RB, Perkins, DO, and McGlashan, TH. "Effect of olanzapine versus placebo on the neuropsychological status of prodromal subjects." April 15, 2004. Link to Item
  - Marquez, E, Keefe, RSE, Purdon, SE, Rock, SL, Alaka, KJ, Ahmed, S, and Mohs, RC. "The relationship of cognition changes and other symptoms following antipsychotic treatment." April 15, 2004. Link to Item
  - Narendran, R, Frankle, WG, Keefe, RSE, Gil, RB, Martinez, D, Kegeles, LS, Talbot, PS, Huang, YY, Hwang, DR, Keilp, JG, Khenissi, L, Cooper, TB, Caton, C, Laruelle, M, and Abi-Dargham, A. "PET imaging of prefrontal dopamine D1 receptors in chronic ketamine human abusers: A model for schizophrenia." April 15, 2004. Link to Item
  - Sharma, T, Harvey, PD, Kumari, V, and Keefe, RSE. "Cognitive enhancement in schizophrenia: Ending the therapeutic nihilism." April 15, 2004. Link to Item
  - Keefe, RSE. "Cognition and the concept of schizotaxia." April 2004. Link to Item
  - Keefe, RSE, Goldberg, TE, Harvey, PD, Gold, JM, Poe, M, and Coughenour, L. "The brief assessment of cognition in schizophrenia: Reliability, sensitivity, and comparison with a standard neurocognitive battery." February 15, 2004. Link to Item
  - Keefe, RSE, Seidman, LJ, Christensen, B, Hamer, RM, and Yurgelun-Todd, D. "Neurocognitive effects of olanzapine and low-dose haloperidol: A two-year treatment study in first episode psychosis." 12th Biennial Winter Workshop on Schizophrenia. DAVOS, SWITZERLAND. February 7, 2004 - February 13, 2004.: ELSEVIER SCIENCE BV, February 15, 2004. Link to Item
  - Keefe, RSE. "The functional hurdle: Connecting through cognition." 12th Biennial Winter Workshop on Schizophrenia. DAVOS, SWITZERLAND. February 7, 2004 - February 13, 2004.: ELSEVIER SCIENCE BV, February 15, 2004. Link to Item
  - Marquez, EM, Keefe, RSE, Purdon, SE, Rock, SL, Alaka, KJ, Ahmed, S, and Mohs, RC. "Is cognitive improvement with antipsychotic treatment pseudospecific?." 12th Biennial Winter Workshop on Schizophrenia. DAVOS, SWITZERLAND. February 7, 2004 - February 13, 2004.: ELSEVIER SCIENCE BV, February 15, 2004. Link to Item
  - Mohs, RC, Alaka, KJ, Keefe, RSE, Purdon, SE, Rock, SL, Wei, H, Marquez, EM, and Ahmed, S. "Functional outcomes and characteristics of olanzapine cognitive super-responders." 12th Biennial Winter Workshop on Schizophrenia. DAVOS, SWITZERLAND. February 7, 2004 - February 13, 2004.: ELSEVIER SCIENCE BV, February 15, 2004. Link to Item
  - Keefe, RSE, Seidman, LJ, Christensen, BK, Hamer, RM, Yurgelun-Todd, DA, Lewine, RRJ, Sitskoorn, MM, Sharma, T, Tohen, M, and Lieberman, JA. "Neurocognitive effects of olanzapine and low-dose haloperidol: A two-year treatment study in first episode psychosis." April 15, 2003. Link to Item
  - Yurgelun-Todd, DA, Renshaw, PF, Wei, H, Keefe, RSE, Charles, HC, Tohen, M, Seidman, LJ, Christensen, BK, Hamer, RM, Sharma, T, Sitskoorn, MM, Gur, RC, Tollefson, GD, and Lieberman, JA. "Improved attention is associated with reductions in frontal lobe lactate levels in first episode psychosis." April 15, 2003. Link to Item
  - Keefe, RSE, Bollini, AM, Courtney, MC, Wilson, WH, and McEvoy, JP. "Successful treatment of self-monitoring deficits predicts psychotic symptom decrease." April 1999. Link to Item
  - Roitman, SEL, Keefe, RSE, Mitropoulou, V, Dupre, RL, and Siever, LJ. "Visuospatial working memory in schizotypal personality disorder." April 1, 1997. Link to Item
  - Roitman, SEL, Keefe, RSE, Dupre, RL, and Siever, LJ. "Visuospatial working memory in schizotypal personality disorder." April 1, 1996. Link to Item
  - Keefe, RSE, Roitman, SEL, Dupre, RL, and Harvey, PD. "Laboratory and clinical tests of spatial working memory." February 1996. Link to Item
  - EPSTEIN, JI, KEEFE, RSE, HARVEY, PD, MOHS, RC, ROITMAN, SEL, DAVIDSON, M, and SIEVER, LJ. "THE EXTENT OF WORKING-MEMORY DEMANDS PREDICTS RESPONSE TO NEUROLEPTIC MEDICATION ON CONTINUOUS PERFORMANCE TESTS." January 1994. Link to Item
  - KEEFE, RSE, BLUM, C, HARVEY, PD, DAVIDSON, M, ROITMAN, SE, and DAVIS, KL. "WORKING-MEMORY DEFICITS IN SCHIZOPHRENICS WITH SEVERE SELF-CARE DYSFUNCTION." January 1994. Link to Item
  - DEVEGVAR, ML, KEEFE, RSE, MOSKOWITZ, J, LEES, S, KALUS, O, KNOTT, P, TRESTMAN, RL, and SIEVER, LJ. "PERFORMANCE ON TESTS SENSITIVE TO FRONTAL-LOBE DYSFUNCTION AND DEFICIT-LIKE SYMPTOMS IN SCHIZOTYPAL PERSONALITY-DISORDER." March 15, 1993. Link to Item
  - KEEFE, RSE, BLUM, C, MERHIGE, DM, LEES, SE, ZOLOT, DM, DAVIDSON, M, HARVEY, PD, and DAVIS, KL. "TASKS FROM MONKEY CORTEX STUDIES AND SPECIFIC PREFRONTAL DYSFUNCTION IN SCHIZOPHRENIA." March 15, 1993. Link to Item
  - KEEFE, RSE, MOHS, RC, SILVERMAN, JM, LOSONCZY, MF, DAVIDSON, M, HORVATH, TB, and DAVIS, KL. "CHARACTERISTICS OF KRAEPELINIAN SCHIZOPHRENIA AND THEIR RELATION TO PREMORBID SOCIOSEXUAL FUNCTIONING." 1990. Link to Item
Teaching & Mentoring
Recent Courses
- NEUROSCI 494: Research Independent Study 2 2019
- NEUROSCI 493: Research Independent Study 1 2018

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

In the News

Global Scholarship

Expertise

Research

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses