Richard Francis Riedel
Associate Professor of Medicine
Novel therapies for soft tissue and bone sarcomas
Current Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Medical Oncology, Medicine 2017
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2000
Contact Information
- Dept of Medicine, 25179 Morris Bldg, Durham, NC 27710
- Duke Box 3198, Durham, NC 27710
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richard.riedel@duke.edu
(919) 681-8031
- Background
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Education, Training, & Certifications
- Fellow in Hematology-Oncology, Medicine, Duke University 2005 - 2007
- Fellow in Hematology-Oncology, Medicine, Duke University 2003 - 2004
- Resident in Medicine, Medicine, Duke University 2000 - 2003
- M.D., Thomas Jefferson University 2000
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Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Medical Oncology, Medicine 2013 - 2017
- Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2007 - 2013
- Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2007
- Associate in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2004 - 2005
- Recognition
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In the News
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MAR 4, 2015 Australian Broadcasting’s “Health Report -
NOV 7, 2014 Duke Chronicle -
OCT 22, 2014 Duke Today
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- Research
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Selected Grants
- YH001/KN035SAR101/1004 awarded by Tracon Pharmaceuticals, Inc. 2022 - 2027
- PTC596-LMS awarded by PTC Therapeutics, Inc 2022 - 2027
- PEAK awarded by Cogent Biosciences, Inc 2022 - 2026
- Trillium TTI-621-03 awarded by PF Argentum IP Holdings LLC 2022 - 2026
- A Randomized, Blinded, Placebo-controlled, Phase 2 Study of INBRX-109 in Unresectable or Metastatic Conventional Chondrosarcoma awarded by Inhibrx, Inc 2022 - 2026
- Phase 3 Randomized Double-Blind Study of Abemaciclib versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma awarded by Sarcoma Alliance for Research Through Collaboration 2022 - 2026
- A Randomized Multicenter Phase 3 Study of Milademetan Versus Trabectedin in Patients with Dedifferentiated Liposarcoma awarded by Rain Therapeutics, Inc. 2022 - 2026
- Vimseltinib (DCC-3014) MOTION awarded by Deciphera Pharmaceuticals, LLC 2022 - 2026
- A Phase 2/3, Randomized, Multicenter Study to Evaluate AL102 in Patients with Progressing Desmoid Tumors awarded by Ayala Pharmaceuticals, Inc 2021 - 2026
- A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3011 Alone and in Combination with Nivolumab in Adult and Adolescent Patients 12 Years and Older with Advanced Solid Tumors awarded by BioAtla, Inc 2021 - 2026
- ENVASARC: A PIVOTAL TRIAL OF ENVAFOLIMAB, AND ENVAFOLIMAB IN COMBINATION WITH IPILIMUMAB, IN PATIENTS WITH ADVANCED OR METASTATIC UNDIFFERENTIATED PLEOMORPHIC SARCOMA OR MYXOFIBROSARCOMA WHO HAVE PROGRESSED ON PRIOR CHEMOTHERAPY awarded by Tracon Pharmaceuticals, Inc. 2020 - 2025
- Long Term Follow-Up of Participants Exposed to GSK3377794 (NYESO- 1c259 T), a Genetically Engineered NY-ESO-1 Specific T Cell Receptor awarded by GlaxoSmithKline 2020 - 2025
- Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered NY-ESO-1-Specific (c259) T Cells, alone or in combination with other agents, in HLA-A2+ Participants with NY-ESO-1 and/or LAGE-1a Positive Solid Tumors (IGNYTE-ESO) awarded by GlaxoSmithKline 2020 - 2025
- A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Nirogacestat Versus Placebo in Adult Patients With Progressing Desmoid Tumors/Aggressive Fibromatosis (DT/AF) awarded by SpringWorks Therapeutics 2019 - 2024
- A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumors after Treatment with Imatinib awarded by Deciphera Pharmaceuticals, LLC 2019 - 2024
- SARC032 awarded by Sarcoma Alliance for Research Through Collaboration 2017 - 2023
- A Multi-Center Phase III, Randomized, Open-Label Trial of Vigil (bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in combination with Irinotecan and Temozolomide as a Second-Line Regimen for Ewing's Sarcoma (CL-PTL-130) awarded by Gradalis, Inc. 2019 - 2023
- A Phase 1/2 Study of the TRK Inhibitor Selitrectinib (BAY 2731954) in Adult and Pediatric Subjects with Previously Treated NTRK Fusion Cancers awarded by Bayer Healthcare Pharmaceuticals Inc 2021 - 2023
- A Phase 1b/2 Dose-Escalation and Expansion Trial of NC-6300 (Nanoparticle Epirubicin) in Patients with Advanced Solid Tumors or Advanced, Metastatic, or Unresectable Soft Tissue Sarcoma"" awarded by NanoCarrier Co., Ltd. 2017 - 2022
- A Phase 1, Dose Escalation Study of Intravenous TK216 in Patients with Relapsed or Refractory Ewing Sarcoma awarded by Oncternal Therapeutics, Inc. 2018 - 2022
- An International, Multicenter, Open-label, Randomized, Phase 3 Study of BLU-285 vs Regorafenib in Patients with Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST) awarded by Blueprint Medicines Corporation 2018 - 2022
- STARTRK-2 awarded by Genentech, Inc. 2017 - 2022
- A PHASE 2-3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND STUDY OF SELINEXOR (KPT-330) VERSUS PLACEBO IN PATIENTS WITH ADVANCED UNRESECTABLE DEDIFFERENTIATED LIPOSARCOMA (DDLS) awarded by Karyopharm Therapeutics 2016 - 2022
- "A Phase 3, Global, Randomized, Double-Blind Trial of Tazemetostat in Combination with Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma" awarded by Epizyme, Inc 2020 - 2022
- A Phase 2 Multi-Center Investigation of Efficacy of ABI-009 (nab-rapamycin) in Patients with Advanced Malignant Perivascular Epithelioid Tumors (PEComa) awarded by AADi LLC 2015 - 2021
- A Double-Blind, Randomized, Placebo-Controlled Phase 3 Study of Orally administered PLX3397 in Subjects with Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath awarded by Daiichi Pharmaceutical Corporation 2015 - 2021
- A blanket protocol to study oral regorafenib in patients with refractory liposarcoma, osteogenic sarcoma, and Ewing/Ewing-like sarcomas awarded by Sarcoma Alliance for Research Through Collaboration 2014 - 2021
- A Randomized, Open-Label, Phase 2 Trial of CMB305 (Sequentially Administered LV305 and G305) and Atezolizumab in Patients with Locally Advanced, Relapsed, or Metastatic Sarcoma Expressing NY-ESO-1 awarded by Immune Design Corp. 2016 - 2021
- A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase III Trial of Crenolanib in Subjects with Advanced or Metastatic Gastrointestinal Stromal Tumors with a D842V Mutation in the PDGFRA Gene awarded by Arog Pharmaceuticals, Inc. 2017 - 2020
- A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin plus Olaratumab versus Doxorubicin plus Placebo in Patients with Advanced or Metastatic Soft Tissue Sarcoma awarded by Eli Lilly and Company 2015 - 2020
- A Phase IB Dose-Escalation Study of TRC105 in combination with Pazopanib in Patients with Advanced Soft Tissue Sarcoma awarded by Tracon Pharmaceuticals, Inc. 2013 - 2020
- A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Determine the Efficacy and Safety of MB305 in Unresectable Locally-advanced or Metastatic NY-ESO-1+ Synovial Sarcoma Subjects Following First-line Systemic Anti-cancer Therapy awarded by Immune Design Corp. 2018 - 2020
- SARC028: A phase II study of anti-PD1 antibody Pembrolizumab (MK-3475) in patients with advanced sarcomas awarded by Sarcoma Alliance for Research Through Collaboration 2015 - 2020
- SARC 024: A blanket protocol to study oral regorafenib in patients with refractory liposarcoma, osteogenic sarcoma, and Ewing/Ewing-like sarcomas - Cohort A awarded by Sarcoma Alliance for Research Through Collaboration 2015 - 2018
- Dissecting Mechanisms of Metastasis Through Comparative Systems Genetics awarded by National Institutes of Health 2008 - 2013
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External Relationships
- Aadi
- Adaptimmune Therapeutics Plc
- Daiichi Sankyo Co., Ltd
- Deciphera
- GlaxoSmithKline
- Springworks
- WCG IRB
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Haddox, Candace L., and Richard F. Riedel. “Emerging predictive biomarkers in the management of bone and soft tissue sarcomas.” Expert Rev Anticancer Ther 23, no. 5 (May 2023): 495–502. https://doi.org/10.1080/14737140.2023.2200169.Full Text Link to Item
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Sag, Alan A., Richard F. Riedel, William C. Eward, Julia D. Visgauss, and Brian E. Brigman. “Hydropneumodissection-Assisted Cryoablation of Recurrent Sarcoma Adjacent to the Sciatic Nerve as a Limb-Sparing Alternative to Hindquarter Amputation.” J Vasc Interv Radiol 34, no. 5 (May 2023): 923-926.e1. https://doi.org/10.1016/j.jvir.2022.12.469.Full Text Link to Item
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Wood, Georgina E., Laurie A. Graves, Elyssa M. Rubin, Damon R. Reed, Richard F. Riedel, and Sandra J. Strauss. “Bad to the Bone: Emerging Approaches to Aggressive Bone Sarcomas.” Am Soc Clin Oncol Educ Book 43 (May 2023): e390306. https://doi.org/10.1200/EDBK_390306.Full Text Link to Item
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Gounder, Mrinal, Ravin Ratan, Thierry Alcindor, Patrick Schöffski, Winette T. van der Graaf, Breelyn A. Wilky, Richard F. Riedel, et al. “Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors.” N Engl J Med 388, no. 10 (March 9, 2023): 898–912. https://doi.org/10.1056/NEJMoa2210140.Full Text Link to Item
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Whiteway, Susan L., Aaron R. Weiss, Safia K. Ahmed, Wendy A. Allen-Rhoades, Viswatej Avutu, Kenneth Cardona, Lara E. Davis, et al. “Joint Adult and Pediatric Working Group as a Successful Platform to Strengthen Adolescent and Young Adult (AYA) Clinical Trial Collaboration: A Report from the NCTN/SARC AYA Clinical Trials Sarcoma Working Group.” J Adolesc Young Adult Oncol, February 1, 2023. https://doi.org/10.1089/jayao.2022.0179.Full Text Link to Item
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Attia, Steven, Vanessa Bolejack, Kristen N. Ganjoo, Suzanne George, Mark Agulnik, Daniel Rushing, Elizabeth T. Loggers, et al. “A phase II trial of regorafenib in patients with advanced Ewing sarcoma and related tumors of soft tissue and bone: SARC024 trial results.” Cancer Med 12, no. 2 (January 2023): 1532–39. https://doi.org/10.1002/cam4.5044.Full Text Link to Item
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Mehren, Margaret von, John M. Kane, Richard F. Riedel, Jason K. Sicklick, Seth M. Pollack, Mark Agulnik, Marilyn M. Bui, et al. “NCCN Guidelines® Insights: Gastrointestinal Stromal Tumors, Version 2.2022.” J Natl Compr Canc Netw 20, no. 11 (November 2022): 1204–14. https://doi.org/10.6004/jnccn.2022.0058.Full Text Link to Item
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Riedel, Richard F., Victoria Chua, Ania Moradkhani, Natalie Krkyan, Amir Ahari, Atsushi Osada, and Sant P. Chawla. “Results of NC-6300 (Nanoparticle Epirubicin) in an Expansion Cohort of Patients with Angiosarcoma.” Oncologist 27, no. 10 (October 1, 2022): 809-e765. https://doi.org/10.1093/oncolo/oyac155.Full Text Link to Item
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Riedel, Richard F., and Mark Agulnik. “Evolving strategies for management of desmoid tumor.” Cancer 128, no. 16 (August 15, 2022): 3027–40. https://doi.org/10.1002/cncr.34332.Full Text Link to Item
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Gounder, Mrinal M., Albiruni Abdul Razak, Neeta Somaiah, Sant Chawla, Javier Martin-Broto, Giovanni Grignani, Scott M. Schuetze, et al. “Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial.” J Clin Oncol 40, no. 22 (August 1, 2022): 2479–90. https://doi.org/10.1200/JCO.21.01829.Full Text Link to Item
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Mehren, Margaret von, John M. Kane, Mark Agulnik, Marilyn M. Bui, Janai Carr-Ascher, Edwin Choy, Mary Connelly, et al. “Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 20, no. 7 (July 2022): 815–33. https://doi.org/10.6004/jnccn.2022.0035.Full Text Link to Item
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Avutu, Viswatej, Aaron R. Weiss, Damon R. Reed, Safia K. Ahmed, Wendy A. Allen-Rhoades, Yen-Lin E. Chen, Lara E. Davis, et al. “Identified Enrollment Challenges of Adolescent and Young Adult Patients on the Nonchemotherapy Arm of Children's Oncology Group Study ARST1321.” J Adolesc Young Adult Oncol 11, no. 3 (June 2022): 328–32. https://doi.org/10.1089/jayao.2021.0103.Full Text Link to Item
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Chawla, Sant P., Brian A. Van Tine, Seth M. Pollack, Kristen N. Ganjoo, Anthony D. Elias, Richard F. Riedel, Steven Attia, et al. “Phase II Randomized Study of CMB305 and Atezolizumab Compared With Atezolizumab Alone in Soft-Tissue Sarcomas Expressing NY-ESO-1.” J Clin Oncol 40, no. 12 (April 20, 2022): 1291–1300. https://doi.org/10.1200/JCO.20.03452.Full Text Link to Item
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Meyer, Mathias, Peter Hohenberger, Daniel Overhoff, Anna Bartsch, Thomas Henzler, Holger Haubenreisser, James Ronald, et al. “Dual-Energy CT Vital Iodine Tumor Burden for Response Assessment in Patients With Metastatic GIST Undergoing TKI Therapy: Comparison With Standard CT and FDG PET/CT Criteria.” Ajr Am J Roentgenol 218, no. 4 (April 2022): 659–69. https://doi.org/10.2214/AJR.21.26636.Full Text Link to Item
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Wagner, Andrew J., Vinod Ravi, Richard F. Riedel, Kristen Ganjoo, Brian A. Van Tine, Rashmi Chugh, Lee Cranmer, et al. “nab-Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors.” J Clin Oncol 39, no. 33 (November 20, 2021): 3660–70. https://doi.org/10.1200/JCO.21.01728.Full Text Link to Item
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Gounder, Mrinal, Albiruni R. Abdul Razak, Adrienne M. Gilligan, Hoyee Leong, Xiwen Ma, Neeta Somaiah, Sant P. Chawla, et al. “Health-related quality of life and pain with selinexor in patients with advanced dedifferentiated liposarcoma.” Future Oncol 17, no. 22 (August 2021): 2923–39. https://doi.org/10.2217/fon-2021-0284.Full Text Link to Item
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Joseph, Cissimol P., Sarah N. Abaricia, Michelle A. Angelis, Kathleen Polson, Robin L. Jones, Yoon-Koo Kang, Richard F. Riedel, et al. “Optimal Avapritinib Treatment Strategies for Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors.” Oncologist 26, no. 4 (April 2021): e622–31. https://doi.org/10.1002/onco.13632.Full Text Link to Item
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Haddox, Candace L., and Richard F. Riedel. “Recent advances in the understanding and management of liposarcoma.” Fac Rev 10 (2021): 1. https://doi.org/10.12703/r/10-1.Full Text Link to Item
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Mehren, Margaret von, John M. Kane, Marilyn M. Bui, Edwin Choy, Mary Connelly, Sarah Dry, Kristen N. Ganjoo, et al. “NCCN Guidelines Insights: Soft Tissue Sarcoma, Version 1.2021.” J Natl Compr Canc Netw 18, no. 12 (December 2, 2020): 1604–12. https://doi.org/10.6004/jnccn.2020.0058.Full Text Link to Item
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Riedel, Richard F., Karla V. Ballman, Yao Lu, Steven Attia, Elizabeth T. Loggers, Kristen N. Ganjoo, Michael B. Livingston, et al. “A Randomized, Double-Blind, Placebo-Controlled, Phase II Study of Regorafenib Versus Placebo in Advanced/Metastatic, Treatment-Refractory Liposarcoma: Results from the SARC024 Study.” Oncologist 25, no. 11 (November 2020): e1655–62. https://doi.org/10.1634/theoncologist.2020-0679.Full Text Link to Item
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Chawla, Sant P., Sanjay Goel, Warren Chow, Fadi Braiteh, Arun S. Singh, Juneko E Grilley Olson, Atsushi Osada, Iulian Bobe, and Richard F. Riedel. “A Phase 1b Dose Escalation Trial of NC-6300 (Nanoparticle Epirubicin) in Patients with Advanced Solid Tumors or Advanced, Metastatic, or Unresectable Soft-tissue Sarcoma.” Clin Cancer Res 26, no. 16 (August 15, 2020): 4225–32. https://doi.org/10.1158/1078-0432.CCR-20-0591.Full Text Link to Item
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Keung, Emily Z., Melissa Burgess, Ruth Salazar, Edwin R. Parra, Jaime Rodrigues-Canales, Vanessa Bolejack, Brian A. Van Tine, et al. “Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab.” Clin Cancer Res 26, no. 6 (March 15, 2020): 1258–66. https://doi.org/10.1158/1078-0432.CCR-19-1824.Full Text Link to Item
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Haddox, Candace L., and Richard F. Riedel. “Individualizing systemic therapy for advanced soft tissue sarcomas based on tumor histology and biology.” Expert Rev Anticancer Ther 20, no. 1 (January 2020): 5–8. https://doi.org/10.1080/14737140.2020.1708198.Full Text Link to Item
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Hendrix, Cristina C., Doreen Matters, Tamara Griffin, Heather Batchelder, Patricia Kramer, Judy R. Prewitt, Loretta Matters, et al. “Academic-Practice Partnership for Caregiver Training and Support: The Duke Elder Family/Caregiver Training (DEFT) Center.” N C Med J 81, no. 4 (2020): 221–27. https://doi.org/10.18043/ncm.81.4.221.Full Text Link to Item
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Davis, Lara E., Vanessa Bolejack, Christopher W. Ryan, Kristen N. Ganjoo, Elizabeth T. Loggers, Sant Chawla, Mark Agulnik, et al. “Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma.” J Clin Oncol 37, no. 16 (June 1, 2019): 1424–31. https://doi.org/10.1200/JCO.18.02374.Full Text Link to Item
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Ray, Emily M., Richard F. Riedel, Thomas W. LeBlanc, Christel N. Rushing, and Anthony N. Galanos. “Assessing the Impact of a Novel Integrated Palliative Care and Medical Oncology Inpatient Service on Health Care Utilization before Hospice Enrollment.” J Palliat Med 22, no. 4 (April 2019): 420–23. https://doi.org/10.1089/jpm.2018.0235.Full Text Link to Item
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Schwartz, Abby J., Richard F. Riedel, Thomas W. LeBlanc, Devi Desai, Carol Jenkins, Ellen Mahoney, Janice Humphreys, and Cristina C. Hendrix. “The experiences of older caregivers of cancer patients following hospital discharge.” Support Care Cancer 27, no. 2 (February 2019): 609–16. https://doi.org/10.1007/s00520-018-4355-2.Full Text Link to Item
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Batich, Kristen A., Richard F. Riedel, John P. Kirkpatrick, Betty C. Tong, William C. Eward, Char Loo Tan, Patricia D. Pittman, Roger E. McLendon, and Katherine B. Peters. “Recurrent Extradural Myxopapillary Ependymoma With Oligometastatic Spread.” Front Oncol 9 (2019): 1322. https://doi.org/10.3389/fonc.2019.01322.Full Text Link to Item
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Riedel, Richard F. “Anti-angiogenic therapy for malignant solitary fibrous tumour: validation through collaboration.” Lancet Oncol 20, no. 1 (January 2019): 14–15. https://doi.org/10.1016/S1470-2045(18)30745-9.Full Text Link to Item
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Gounder, Mrinal M., Michelle R. Mahoney, Brian A. Van Tine, Vinod Ravi, Steven Attia, Hari A. Deshpande, Abha A. Gupta, et al. “Sorafenib for Advanced and Refractory Desmoid Tumors.” N Engl J Med 379, no. 25 (December 20, 2018): 2417–28. https://doi.org/10.1056/NEJMoa1805052.Full Text Link to Item
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Riedel, Richard F., Robin L. Jones, Antoine Italiano, Chet Bohac, Juliette C. Thompson, Kerstin Mueller, Zaeem Khan, Seth M. Pollack, and Brian A. Van Tine. “Systemic Anti-Cancer Therapy in Synovial Sarcoma: A Systematic Review.” Cancers (Basel) 10, no. 11 (November 1, 2018). https://doi.org/10.3390/cancers10110417.Full Text Link to Item
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Wisdom, Amy J., Yvonne M. Mowery, Richard F. Riedel, and David G. Kirsch. “Rationale and emerging strategies for immune checkpoint blockade in soft tissue sarcoma.” Cancer 124, no. 19 (October 1, 2018): 3819–29. https://doi.org/10.1002/cncr.31517.Full Text Link to Item
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Vlahovic, Gordana, Kellen L. Meadows, Ace J. Hatch, Jingquan Jia, Andrew B. Nixon, Hope E. Uronis, Michael A. Morse, et al. “A Phase I Trial of the IGF-1R Antibody Ganitumab (AMG 479) in Combination with Everolimus (RAD001) and Panitumumab in Patients with Advanced Cancer.” Oncologist 23, no. 7 (July 2018): 782–90. https://doi.org/10.1634/theoncologist.2016-0377.Full Text Link to Item
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Mehren, Margaret von, R Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Kristen N. Ganjoo, Suzanne George, et al. “Soft Tissue Sarcoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 16, no. 5 (May 2018): 536–63. https://doi.org/10.6004/jnccn.2018.0025.Full Text Link to Item
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Choe, Jennifer, and Richard Riedel. “Making progress in a rare disease: emerging therapeutics in soft tissue sarcomas.” F1000res 7 (2018). https://doi.org/10.12688/f1000research.15868.1.Full Text Link to Item
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Cancer Genome Atlas Research Network. Electronic address: elizabeth.demicco@sinaihealthsystem.ca, Chris, and Chris Cancer Genome Atlas Research Network. “Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas.” Cell 171, no. 4 (November 2, 2017): 950-965.e28. https://doi.org/10.1016/j.cell.2017.10.014.Full Text Link to Item
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Tawbi, Hussein A., Melissa Burgess, Vanessa Bolejack, Brian A. Van Tine, Scott M. Schuetze, James Hu, Sandra D’Angelo, et al. “Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.” Lancet Oncol 18, no. 11 (November 2017): 1493–1501. https://doi.org/10.1016/S1470-2045(17)30624-1.Full Text Link to Item
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Riedel, Richard F., Kim Slusser, Steve Power, Christopher A. Jones, Thomas W. LeBlanc, Arif H. Kamal, Devi Desai, et al. “Improvements in Patient and Health System Outcomes Using an Integrated Oncology and Palliative Medicine Approach on a Solid Tumor Inpatient Service.” J Oncol Pract 13, no. 9 (September 2017): e738–48. https://doi.org/10.1200/JOP.2017.022749.Full Text Link to Item
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Tap, William D., Zsuzsanna Papai, Brian A. Van Tine, Steven Attia, Kristen N. Ganjoo, Robin L. Jones, Scott Schuetze, et al. “Doxorubicin plus evofosfamide versus doxorubicin alone in locally advanced, unresectable or metastatic soft-tissue sarcoma (TH CR-406/SARC021): an international, multicentre, open-label, randomised phase 3 trial.” Lancet Oncol 18, no. 8 (August 2017): 1089–1103. https://doi.org/10.1016/S1470-2045(17)30381-9.Full Text Link to Item
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Riedel, Richard F., Kellen L. Meadows, Paula H. Lee, Michael A. Morse, Hope E. Uronis, Gerard C. Blobe, Daniel J. George, et al. “Phase I study of pazopanib plus TH-302 in advanced solid tumors.” Cancer Chemother Pharmacol 79, no. 3 (March 2017): 611–19. https://doi.org/10.1007/s00280-017-3256-2.Full Text Link to Item
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Tap, W., Z. Papai, B. van Tine, S. Attia, K. Ganjoo, R. L. Jones, S. Schuetze, et al. “Randomized phase 3, multicenter, open-label study comparing evofosfamide (Evo) in combination with doxorubicin (D) vs. D alone in patients (pts) with advanced soft tissue sarcoma (STS): Study TH-CR-406/SARC021.” Annals of Oncology 27 (October 1, 2016): vi483. https://doi.org/10.1093/annonc/mdw388.01.Full Text
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Wagner, Andrew J., Mark Agulnik, Michael C. Heinrich, Daruka Mahadevan, Richard F. Riedel, Margaret von Mehren, Jonathan Trent, et al. “Dose-escalation study of a second-generation non-ansamycin HSP90 inhibitor, onalespib (AT13387), in combination with imatinib in patients with metastatic gastrointestinal stromal tumour.” Eur J Cancer 61 (July 2016): 94–101. https://doi.org/10.1016/j.ejca.2016.03.076.Full Text Link to Item
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Mehren, Margaret von, R Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Ernest U. Conrad, Kristen N. Ganjoo, et al. “Soft Tissue Sarcoma, Version 2.2016, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 14, no. 6 (June 2016): 758–86. https://doi.org/10.6004/jnccn.2016.0078.Full Text Link to Item
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Whitley, Melodi Javid, Diana M. Cardona, Alexander L. Lazarides, Ivan Spasojevic, Jorge M. Ferrer, Joan Cahill, Chang-Lung Lee, et al. “A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.” Sci Transl Med 8, no. 320 (January 6, 2016): 320ra4. https://doi.org/10.1126/scitranslmed.aad0293.Full Text Link to Item
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Hendrix, Cristina C., Donald E. Bailey, Karen E. Steinhauser, Maren K. Olsen, Karen M. Stechuchak, Sarah G. Lowman, Abby J. Schwartz, et al. “Effects of enhanced caregiver training program on cancer caregiver's self-efficacy, preparedness, and psychological well-being.” Support Care Cancer 24, no. 1 (January 2016): 327–36. https://doi.org/10.1007/s00520-015-2797-3.Full Text Link to Item
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Gwin, W., and R. F. Riedel. “Chemotherapy in soft-tissue sarcoma: where do we go from here?” Oncology (Williston Park, N.Y.) 29, no. 1 (January 1, 2015).
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Gwin, W., and R. F. Riedel. “Chemotherapy in soft-tissue sarcoma: where do we go from here?” Oncology (Williston Park, N.Y.) 29, no. 1 (January 1, 2015).
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Gwin, William, and Richard F. Riedel. “Chemotherapy in soft-tissue sarcoma: where do we go from here?” Oncology (Williston Park) 29, no. 1 (January 2015): 50–53.Link to Item
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Jiang, Xiaoyin, H Bryan Anderson, Cynthia D. Guy, Paul J. Mosca, Richard F. Riedel, and Diana M. Cardona. “Rhabdomyosarcomatous Transformation of a Gastrointestinal Stromal Tumor following Treatment with Imatinib.” Case Rep Oncol Med 2015 (2015): 317493. https://doi.org/10.1155/2015/317493.Full Text Link to Item
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Slusser, K., S. Power, C. A. Jones, T. W. LeBlanc, A. Kamal, D. Desai, D. Allen, and A. N. Galanos. “Early palliative care on an inpatient oncology unit: Impact of a novel co-rounding partnership on patient and health system outcomes.” J Clin Oncol 32, no. 31_suppl (November 2014): 3. https://doi.org/10.1200/jco.2014.32.31_suppl.3.Full Text Link to Item
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Mehren, Margaret von, R Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad, et al. “Gastrointestinal stromal tumors, version 2.2014.” J Natl Compr Canc Netw 12, no. 6 (June 2014): 853–62. https://doi.org/10.6004/jnccn.2014.0080.Full Text Link to Item
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Mehren, Margaret von, R Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad, et al. “Soft tissue sarcoma, version 2.2014.” J Natl Compr Canc Netw 12, no. 4 (April 2014): 473–83. https://doi.org/10.6004/jnccn.2014.0053.Full Text Link to Item
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Meadows, Kellen L., Paula H. Lee, Richard F. Riedel, Michael A. Morse, Hope E. Uronis, Gerard C. Blobe, Daniel J. George, Jeffrey Crawford, and Herbert I. Hurwitz. “Abstract C61: Phase I Study of pazopanib in combination with the investigational hypoxia-targeted drug TH-302.” Molecular Cancer Therapeutics 12, no. 11_Supplement (November 1, 2013): C61–C61. https://doi.org/10.1158/1535-7163.targ-13-c61.Full Text
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Demetri, George D., Sant P. Chawla, Isabelle Ray-Coquard, Axel Le Cesne, Arthur P. Staddon, Mohammed M. Milhem, Nicolas Penel, et al. “Results of an international randomized phase III trial of the mammalian target of rapamycin inhibitor ridaforolimus versus placebo to control metastatic sarcomas in patients after benefit from prior chemotherapy.” J Clin Oncol 31, no. 19 (July 1, 2013): 2485–92. https://doi.org/10.1200/JCO.2012.45.5766.Full Text Link to Item
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Larrier, Nicole A., David G. Kirsch, Richard F. Riedel, Howard Levinson, William C. Eward, and Brian E. Brigman. “Practical radiation oncology for extremity sarcomas.” Surg Oncol Clin N Am 22, no. 3 (July 2013): 433–43. https://doi.org/10.1016/j.soc.2013.02.004.Full Text Link to Item
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Cuneo, Kyle C., Richard F. Riedel, Leslie G. Dodd, David H. Harpole, and David G. Kirsch. “Pathologic complete response of a malignant peripheral nerve sheath tumor in the lung treated with neoadjuvant Ifosfamide and radiation therapy.” J Clin Oncol 30, no. 28 (October 1, 2012): e291–93. https://doi.org/10.1200/JCO.2012.42.8797.Full Text Link to Item
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Mehren, Margaret von, Robert S. Benjamin, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad, Thomas F. DeLaney, Kristen N. Ganjoo, et al. “Soft tissue sarcoma, version 2.2012: featured updates to the NCCN guidelines.” J Natl Compr Canc Netw 10, no. 8 (August 2012): 951–60. https://doi.org/10.6004/jnccn.2012.0099.Full Text Link to Item
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Vlahovic, Gordana, Kellen L. Meadows, Hope E. Uronis, Michael A. Morse, Gerard C. Blobe, Richard F. Riedel, S Yousuf Zafar, et al. “A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors.” Cancer Chemother Pharmacol 70, no. 1 (July 2012): 95–102. https://doi.org/10.1007/s00280-012-1889-8.Full Text Link to Item
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Riedel, Richard F., Alessandro Porrello, Emily Pontzer, Emily J. Chenette, David S. Hsu, Bala Balakumaran, Anil Potti, Joseph Nevins, and Phillip C. Febbo. “Retraction in part: A genomic approach to identify molecular pathways associated with chemotherapy resistance.” Mol Cancer Ther 11, no. 5 (May 2012): 1214–15. https://doi.org/10.1158/1535-7163.MCT-12-0210.Full Text Link to Item
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Riedel, Richard F. “Systemic therapy for advanced soft tissue sarcomas: highlighting novel therapies and treatment approaches.” Cancer 118, no. 6 (March 15, 2012): 1474–85. https://doi.org/10.1002/cncr.26415.Full Text Link to Item
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Kim, Suzy, Rebecca D. Dodd, Jeffrey K. Mito, Yan Ma, Yongbaek Kim, Richard F. Riedel, and David G. Kirsch. “Efficacy of phosphatidylinositol-3 kinase inhibitors in a primary mouse model of undifferentiated pleomorphic sarcoma.” Sarcoma 2012 (2012): 680708. https://doi.org/10.1155/2012/680708.Full Text Link to Item
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Riedel, Richard F., Robert G. Maki, and Andrew J. Wagner. “Targeted therapy in sarcoma: should we be lumpers or splitters?” Am Soc Clin Oncol Educ Book, 2012, 652–57. https://doi.org/10.14694/EdBook_AM.2012.32.204.Full Text Link to Item
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Riedel, Richard F. “Targeted agents for sarcoma: is individualized therapy possible in such a diverse tumor type?” Semin Oncol 38 Suppl 3 (October 2011): S30–42. https://doi.org/10.1053/j.seminoncol.2011.09.003.Full Text Link to Item
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Hsu, D. S., C. R. Acharya, B. S. Balakumaran, R. F. Riedel, M. K. Kim, M. Stevenson, S. Tuchman, et al. “Erratum: Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 13 (5312-5317) DOI: 10.1073/pnas.0900827106).” Proceedings of the National Academy of Sciences of the United States of America 108, no. 35 (August 30, 2011): 14705. https://doi.org/10.1073/pnas.1111196108.Full Text
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Smith, Jason L., and Richard F. Riedel. “Emerging therapeutic targets for soft tissue sarcoma.” Curr Oncol Rep 13, no. 4 (August 2011): 350–58. https://doi.org/10.1007/s11912-011-0175-y.Full Text Link to Item
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Chawla, S. P., J. Blay, I. L. Ray-Coquard, A. Le Cesne, A. P. Staddon, M. M. Milhem, N. Penel, et al. “Results of the phase III, placebo-controlled trial (SUCCEED) evaluating the mTOR inhibitor ridaforolimus (R) as maintenance therapy in advanced sarcoma patients (pts) following clinical benefit from prior standard cytotoxic chemotherapy (CT).” J Clin Oncol 29, no. 15_suppl (May 20, 2011): 10005.Link to Item
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Chawla, S. P., J. Blay, I. L. Ray-Coquard, A. Le Cesne, A. P. Staddon, M. M. Milhem, N. Penel, et al. “Results of the phase III, placebo-controlled trial (SUCCEED) evaluating the mTOR inhibitor ridaforolimus (R) as maintenance therapy in advanced sarcoma patients (pts) following clinical benefit from prior standard cytotoxic chemotherapy (CT).” Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): 10005–10005. https://doi.org/10.1200/jco.2011.29.15_suppl.10005.Full Text
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Palta, Manisha, Richard F. Riedel, James J. Vredenburgh, Thomas J. Cummings, Scott Green, Zheng Chang, and John P. Kirkpatrick. “Primary meningeal rhabdomyosarcoma.” Sarcoma 2011 (2011): 312802. https://doi.org/10.1155/2011/312802.Full Text Link to Item
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Demetri, George D., Scott Antonia, Robert S. Benjamin, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad, Thomas F. DeLaney, et al. “Soft tissue sarcoma.” J Natl Compr Canc Netw 8, no. 6 (June 2010): 630–74. https://doi.org/10.6004/jnccn.2010.0049.Full Text Link to Item
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Demetri, George D., Margaret von Mehren, Cristina R. Antonescu, Ronald P. DeMatteo, Kristen N. Ganjoo, Robert G. Maki, Peter W. T. Pisters, et al. “NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors.” J Natl Compr Canc Netw 8 Suppl 2, no. 0 2 (April 2010): S1-41. https://doi.org/10.6004/jnccn.2010.0116.Full Text Link to Item
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Mito, Jeffrey K., Richard F. Riedel, Leslie Dodd, Guy Lahat, Alexander J. Lazar, Rebecca D. Dodd, Lars Stangenberg, et al. “Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.” Plos One 4, no. 11 (November 30, 2009): e8075. https://doi.org/10.1371/journal.pone.0008075.Full Text Link to Item
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Howard, L. A., K. E. Bullock, J. C. Bendell, H. E. Uronis, G. Vlahovic, G. C. Blobe, R. F. Riedel, A. B. Nixon, J. P. Gockerman, and H. I. Hurwitz. “Bevacizumab (B) plus everolimus (E) and panitumumab (P) in refractory advanced solid tumors.” J Clin Oncol 27, no. 15_suppl (May 20, 2009): 3551.Link to Item
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Riedel, Richard F., Nicole Larrier, Leslie Dodd, David Kirsch, Salutario Martinez, and Brian E. Brigman. “The clinical management of chondrosarcoma.” Curr Treat Options Oncol 10, no. 1–2 (April 2009): 94–106. https://doi.org/10.1007/s11864-009-0088-2.Full Text Link to Item
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Hsu, David S., Chaitanya R. Acharya, Bala S. Balakumaran, Richard F. Riedel, Mickey K. Kim, Marvaretta Stevenson, Sascha Tuchman, et al. “Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer.” Proc Natl Acad Sci U S A 106, no. 13 (March 31, 2009): 5312–17. https://doi.org/10.1073/pnas.0900827106.Full Text Link to Item
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Riedel, Richard F., Alessandro Porrello, Emily Pontzer, Emily J. Chenette, David S. Hsu, Bala Balakumaran, Anil Potti, Joseph Nevins, and Phillip G. Febbo. “A genomic approach to identify molecular pathways associated with chemotherapy resistance.” Mol Cancer Ther 7, no. 10 (October 2008): 3141–49. https://doi.org/10.1158/1535-7163.MCT-08-0642.Full Text Link to Item
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Hsu, S. D., C. R. Acharya, R. F. Riedel, R. C. Redman, K. S. Garman, H. K. Dressman, G. Ginsburg, S. Powers, D. Mu, and A. Potti. “Use of co-activation of lung cancer specific developmental pathway genes, TTF-1, NKX2-8, and PAX9, to predict prognosis and guide therapeutic strategies.” J Clin Oncol 26, no. 15_suppl (May 20, 2008): 7511.Link to Item
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Riedel, R. F., D. Friedman, and P. G. Febbo. “A genomic approach to identify therapeutic targets in histologic subtypes of soft tissue sarcoma.” J Clin Oncol 26, no. 15_suppl (May 20, 2008): 10577.Link to Item
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Hsu, S. D., C. R. Acharya, R. F. Riedel, R. C. Redman, K. S. Garman, H. K. Dressman, G. Ginsburg, S. Powers, D. Mu, and A. Potti. “Use of co-activation of lung cancer specific developmental pathway genes, TTF-1, NKX2–8, and PAX9, to predict prognosis and guide therapeutic strategies.” Journal of Clinical Oncology 26, no. 15_suppl (May 20, 2008): 7511–7511. https://doi.org/10.1200/jco.2008.26.15_suppl.7511.Full Text
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Riedel, R. F., D. Friedman, and P. G. Febbo. “A genomic approach to identify therapeutic targets in histologic subtypes of soft tissue sarcoma.” Journal of Clinical Oncology 26, no. 15_suppl (May 20, 2008): 10577–10577. https://doi.org/10.1200/jco.2008.26.15_suppl.10577.Full Text
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Hsu, David S., Bala S. Balakumaran, Chaitanya R. Acharya, Vanja Vlahovic, Kelli S. Walters, Katherine Garman, Carey Anders, et al. “Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer.” J Clin Oncol 25, no. 28 (October 1, 2007): 4350–57. https://doi.org/10.1200/JCO.2007.11.0593.Full Text Link to Item
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Riedel, Richard F., Carolyn Andrews, Jennifer Garst, Frank Dunphy, James E. Herndon, Susan Blackwell, Sally Barbour, and Jeffrey Crawford. “A phase II trial of carboplatin/vinorelbine with pegfilgrastim support for the treatment of patients with advanced non-small cell lung cancer.” J Thorac Oncol 2, no. 6 (June 2007): 520–25. https://doi.org/10.1097/JTO.0b013e318060107c.Full Text Link to Item
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Riedel, Richard F., Jeffrey Crawford, Frank Dunphy, James E. Herndon, Jennifer Garst, and Michael J. Kelley. “Phase II study of carboplatin, irinotecan, and thalidomide combination in patients with extensive stage small-cell lung cancer.” Lung Cancer 54, no. 3 (December 2006): 431–32. https://doi.org/10.1016/j.lungcan.2006.08.008.Full Text Link to Item
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Riedel, Richard F., Xiaofei Wang, Meg McCormack, Eric Toloza, Gustavo S. Montana, Gilbert Schreiber, and Michael J. Kelley. “Impact of a multidisciplinary thoracic oncology clinic on the timeliness of care.” J Thorac Oncol 1, no. 7 (September 2006): 692–96.Link to Item
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Riedel, Richard F., and William R. Burfeind. “Thymoma: benign appearance, malignant potential.” Oncologist 11, no. 8 (September 2006): 887–94. https://doi.org/10.1634/theoncologist.11-8-887.Full Text Link to Item
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Riedel, Richard F., and Phillip G. Febbo. “Epidermal growth factor receptor mutations predict sensitivity to gefitinib in patients with non-small-cell lung cancer.” Future Oncol 1, no. 4 (August 2005): 461–66. https://doi.org/10.2217/14796694.1.4.461.Full Text Link to Item
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Riedel, Richard F., and Jeffrey Crawford. “Small-cell lung cancer: a review of clinical trials.” Semin Thorac Cardiovasc Surg 15, no. 4 (October 2003): 448–56. https://doi.org/10.1053/s1043-0679(03)00098-4.Full Text Link to Item
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Luetteke, N. C., T. H. Qiu, S. E. Fenton, K. L. Troyer, R. F. Riedel, A. Chang, and D. C. Lee. “Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development.” Development 126, no. 12 (June 1999): 2739–50. https://doi.org/10.1242/dev.126.12.2739.Full Text Link to Item
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Salomoni, P., M. A. Wasik, R. F. Riedel, K. Reiss, J. K. Choi, T. Skorski, and B. Calabretta. “Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant.” J Exp Med 187, no. 12 (June 15, 1998): 1995–2007. https://doi.org/10.1084/jem.187.12.1995.Full Text Link to Item
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Berkowitz, E. A., K. B. Seroogy, J. A. Schroeder, W. E. Russell, E. P. Evans, R. F. Riedel, H. K. Phillips, C. A. Harrison, D. C. Lee, and N. C. Luetteke. “Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues.” Cell Growth Differ 7, no. 9 (September 1996): 1271–82.Link to Item
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Book Sections
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Larrier, N., W. C. Eward, and R. F. Riedel. “Bone Sarcomas.” In Cancer Consult: Expertise for Clinical Practice, 687–95, 2014. https://doi.org/10.1002/9781118589199.ch105.Full Text
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Larrier, Nicole, William C. Eward, and Richard F. Riedel. “Bone sarcomas.” In CANCER CONSULT: EXPERTISE FOR CLINICAL PRACTICE, 689–95, 2014.Link to Item
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Other Articles
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Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Retraction: Genomic signatures to guide the use of chemotherapeutics.” Nat Med, January 2011. https://doi.org/10.1038/nm0111-135.Full Text Link to Item
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“Retraction. Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer. J Clin Oncol 25:4350–7, 2007.” J Clin Oncol, December 10, 2010. https://doi.org/10.1200/JCO.2010.33.7311.Full Text Link to Item
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300)).” Nature Medicine, August 1, 2008. https://doi.org/10.1038/nm0808-889.Full Text
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300)).” Nature Medicine, November 1, 2007. https://doi.org/10.1038/nm1107-1388.Full Text
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Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Genomic signatures to guide the use of chemotherapeutics.” Nat Med, November 2006. https://doi.org/10.1038/nm1491.Full Text Link to Item
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Conference Papers
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Kasper, B., R. Ratan, T. Alcindor, P. Schoeffski, W. T. A. van der Graaf, B. A. Wilky, R. F. Riedel, et al. “LBA2 DeFi: A phase III, randomized controlled trial of nirogacestat versus placebo for progressing desmoid tumors (DT).” In Annals of Oncology, 33:S1435–36. Elsevier BV, 2022. https://doi.org/10.1016/j.annonc.2022.08.075.Full Text
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Dickson, Mark Andrew, Vinod Ravi, Richard F. Riedel, Kristen N. Ganjoo, Brian Andrew Van Tine, Rashmi Chugh, Lee D. Cranmer, et al. “nab-Sirolimus for patients with advanced malignant PEComa with or without prior mTOR inhibitors: Biomarker results from AMPECT and an expanded access program.” In Journal of Clinical Oncology, Vol. 40, 2022.Link to Item
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Hohenberger, Peter, Mathias Meyer, Thomas Henzler, Richard F. Riedel, Christina Messiou, Daniele Marin, and Stefan Schoenberg. “Dual energy analysis of TKI response in GIST - results of a prospective trial.” In Cancer Research, Vol. 82, 2022.Link to Item
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Copeland, Tabitha, Roman Groisberg, Don S. Dizon, Andrew Elliott, Galina Lagos, Andreas Seeber, Margaret von Mehren, et al. “Multiomic analysis to reveal distinct molecular profiles of uterine and nonuterine leiomyosarcoma.” In Journal of Clinical Oncology, 39:11555–11555. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.11555.Full Text
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Lagos, Galina, Roman Groisberg, Don S. Dizon, Andrew Elliott, Tabitha Copeland, Andreas Seeber, Geoffrey Thomas Gibney, et al. “Large scale multiomic analysis suggests mechanisms of resistance to immunotherapy in leiomyosarcoma.” In Journal of Clinical Oncology, 39:11512–11512. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.11512.Full Text
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Ludwig, Joseph Aloysius, Noah C. Federman, Peter Meade Anderson, Margaret E. Macy, Richard F. Riedel, Lara E. Davis, Najat C. Daw, et al. “TK216 for relapsed/refractory Ewing sarcoma: Interim phase 1/2 results.” In Journal of Clinical Oncology, 39:11500–11500. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.11500.Full Text
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Naqash, Abdul Rafeh, Geraldine Helen O’Sullivan Coyne, Nancy Moore, Elad Sharon, Naoko Takebe, Kristin K. Fino, Katherine V. Ferry-Galow, et al. “Phase II study of atezolizumab in advanced alveolar soft part sarcoma (ASPS).” In Journal of Clinical Oncology, 39:11519–11519. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.11519.Full Text
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Riedel, Richard F., Victoria S. Chua, Ted Kim, Jonathan Dang, Kitty Zheng, Ania Moradkhani, Atsushi Osada, and Sant P. Chawla. “Results of NC-6300 (nanoparticle epirubicin) in an expansion cohort of patients with angiosarcoma.” In Journal of Clinical Oncology, 39:11543–11543. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.11543.Full Text
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Schuetze, Scott, Karla V. Ballman, Kristen N. Ganjoo, Elizabeth J. Davis, Jeffrey A. Morgan, Gabriel Tinoco, Melissa Amber Burgess, et al. “P10015/SARC033: A phase 2 trial of trametinib in patients with advanced epithelioid hemangioendothelioma (EHE).” In Journal of Clinical Oncology, 39:11503–11503. American Society of Clinical Oncology (ASCO), 2021. https://doi.org/10.1200/jco.2021.39.15_suppl.11503.Full Text
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Ludwig, J. A., N. Federman, P. Anderson, M. E. Macy, L. E. Davis, R. F. Riedel, J. A. Muscal, et al. “1620O Phase I study of TK216, a novel anti-ETS agent for Ewing sarcoma.” In Annals of Oncology, 31:S972–S972. Elsevier BV, 2020. https://doi.org/10.1016/j.annonc.2020.08.1846.Full Text
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Ingham, Matthew, Michelle R. Mahoney, Fabrizio Remotti, Ardaman Shergill, Mark Andrew Dickson, Richard F. Riedel, Steven Attia, et al. “A randomized phase II study of MLN0128 (M) versus pazopanib (P) in patients (pt) with advanced sarcoma (Alliance A091304).” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Kopp, Lisa M., Damon R. Reed, Safia K. Ahmed, Wendy Allen-Rhoades, Viswatej Avutu, Yen-Lin Chen, Lara E. Davis, et al. “Enrollment barriers of adolescents and young adults (AYA) on the non-chemotherapy arm of ARST1321.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Wagner, Andrew J., Vinod Ravi, Richard F. Riedel, Kristen N. Ganjoo, Brian Andrew Van Tine, Rashmi Chugh, Lee D. Cranmer, et al. “Long-term follow-up for duration of response (DoR) after weekly nab-sirolimus in patients with advanced malignant perivascular epithelioid cell tumors (PEComa): Results from a registrational open-label phase II trial, AMPECT.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Burgess, Melissa Amber, Vanessa Bolejack, Scott Schuetze, Brian Andrew Van Tine, Steven Attia, Richard F. Riedel, James S. Hu, et al. “Clinical activity of pembrolizumab (P) in undifferentiated pleomorphic sarcoma (UPS) and dedifferentiated/pleomorphic liposarcoma (LPS): Final results of SARC028 expansion cohorts.” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.Link to Item
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Chawla, Sant P., Brian Andrew Van Tine, Seth Pollack, Kristen N. Ganjoo, Anthony D. Elias, Richard F. Riedel, Steven Attia, et al. “A phase II randomized study of CMB305 and atezolizumab versus atezolizumab in NY-ESO-1(+) soft tissue sarcoma: Analysis of immunogenicity, tumor control, and patient survival.” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.Link to Item
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Wagner, Andrew J., Vinod Ravi, Kristen N. Ganjoo, Brian Andrew Van Tine, Richard F. Riedel, Rashmi Chugh, Lee D. Cranmer, et al. “ABI-009 (nab-sirolimus) in advanced malignant perivascular epithelioid cell tumors (PEComa): Preliminary efficacy, safety, and mutational status from AMPECT, an open label phase II registration trial.” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.Link to Item
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Gounder, Mrinal M., Neeta Somaiah, Steven Attia, Sant P. Chawla, Victor Manuel Villalobos, Bartosz Chmielowski, Melissa Amber Burgess, et al. “Phase 2 results of selinexor in advanced de-differentiated (DDLS) liposarcoma (SEAL) study: A phase 2/3, randomized, double blind, placebo controlled cross-over study.” In Journal of Clinical Oncology, 36:11512–11512. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.11512.Full Text
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Mowery, Yvonne Marie, Karla V. Ballman, Richard F. Riedel, Brian E. Brigman, Steven Attia, Christian Frederick Meyer, Scott Schuetze, et al. “SU2C-SARC032: A phase II randomized controlled trial of neoadjuvant pembrolizumab with radiotherapy and adjuvant pembrolizumab for high-risk soft tissue sarcoma.” In Journal of Clinical Oncology, 36:TPS11588–TPS11588. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.tps11588.Full Text
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Ravi, Vinod, Andrew Scott Brohl, Sant P. Chawla, Steven Attia, Richard F. Riedel, David A. Liebner, Katherine Anne Thornton, et al. “Detection of endoglin-expressing CTCs in patients enrolled in an adaptive enrichment phase 3 trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma (TAPPAS).” In Journal of Clinical Oncology, 36:e23570–e23570. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.e23570.Full Text
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Ravi, Vinod, Andrew Scott Brohl, Sant P. Chawla, Steven Attia, Richard F. Riedel, David A. Liebner, Katherine Anne Thornton, et al. “TAPPAS: An adaptive enrichment phase 3 trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma.” In Journal of Clinical Oncology, 36:TPS11590–TPS11590. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.tps11590.Full Text
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Riedel, Richard F., Karla V. Ballman, Yao Lu, Steven Attia, Elizabeth Trice Loggers, Kristen N. Ganjoo, Michael B. Livingston, et al. “A randomized, double-blind, placebo-controlled, phase II study of regorafenib vs placebo in advanced/metastatic, treatment-refractory liposarcoma: results from the SARC024 study.” In Journal of Clinical Oncology, 36:11505–11505. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.11505.Full Text
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Wagner, Andrew J., Richard F. Riedel, Brian Andrew Van Tine, Rashmi Chugh, Kristen N. Ganjoo, Lee D. Cranmer, Seth Pollack, et al. “Mutational analysis and safety/efficacy in a phase 2 multi-center investigation of ABI-009 (nab-rapamycin) in patients with advanced malignant perivascular epithelioid cell tumors (PEComa).” In Journal of Clinical Oncology, 36:TPS11589–TPS11589. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.tps11589.Full Text
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Chawla, S., B. A. Van Tine, S. Pollack, K. Ganjoo, A. Elias, R. F. Riedel, S. Attia, et al. “A phase 2 study of CMB305 and atezolizumab in NY-ESO-1+soft tissue sarcoma: Interim analysis of immunogenicity, tumor control and survival.” In Annals of Oncology, Vol. 28. OXFORD UNIV PRESS, 2017.Link to Item
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Attia, Steven, Vanessa Bolejack, Kristen N. Ganjoo, Suzanne George, Mark Agulnik, Daniel A. Rushing, Elizabeth Trice Loggers, et al. “A phase II trial of regorafenib (REGO) in patients (pts) with advanced Ewing sarcoma and related tumors (EWS) of soft tissue and bone: SARC024 trial results.” In Journal of Clinical Oncology, 35:11005–11005. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.11005.Full Text
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Burgess, Melissa Amber, Vanessa Bolejack, Brian Andrew Van Tine, Scott Schuetze, James Hu, Sandra P. D’Angelo, Steven Attia, et al. “Multicenter phase II study of pembrolizumab (P) in advanced soft tissue (STS) and bone sarcomas (BS): Final results of SARC028 and biomarker analyses.” In Journal of Clinical Oncology, 35:11008–11008. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.11008.Full Text
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Burgess, Melissa Amber, Jason Roszik, Brian Andrew Van Tine, James Hu, Scott Schuetze, Sandra P. D’Angelo, Steven Attia, et al. “Correlation of circulating PD-L2 levels with outcomes of therapy with the anti-PD-1 antibody pembrolizumab (P) in patients (pts) with advanced soft tissue sarcomas (STS): Biomarker analysis of SARC028.” In Journal of Clinical Oncology, 35:60–60. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.7_suppl.60.Full Text
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Rav, Emily Miller, Richard F. Riedel, Christel N. Rushing, and Anthony N. Galanos. “Healthcare utilization among cancer patients prior to hospice.” In Journal of Clinical Oncology, Vol. 34. AMER SOC CLINICAL ONCOLOGY, 2016.Link to Item
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Attia, Steven, Kamalesh Kumar Sankhala, Richard F. Riedel, Steven Ian Robinson, Robert Martin Conry, Patrick McKay Boland, Minal A. Barve, et al. “A phase 1B/ phase 2A study of TRC105 (Endoglin Antibody) in combination with pazopanib (P) in patients (pts) with advanced soft tissue sarcoma (STS).” In Journal of Clinical Oncology, 34:11016–11016. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.11016.Full Text
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Gounder, Mrinal M., Andrew J. Wagner, Neeta Somaiah, Richard F. Riedel, Gary K. Schwartz, Steven Attia, Albiruni R. A. Razak, et al. “The Selinexor in Advanced Liposarcoma (SEAL) study: A phase 2/3, multicenter, randomized, double blind study of selinexor versus placebo in patients with advanced, unresectable, dedifferentiated liposarcoma (DDLS).” In Journal of Clinical Oncology, 34:TPS11072–TPS11072. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.tps11072.Full Text
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Patel, Krish, Lowell T. Nicholson, and Richard F. Riedel. “Defining the characteristics of medical oncology patients requiring inpatient hospital admission.” In Journal of Clinical Oncology, 34:e18023–e18023. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.e18023.Full Text
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Tawbi, Hussein Abdul-Hassan, Melissa Amber Burgess, John Crowley, Brian Andrew Van Tine, James Hu, Scott Schuetze, Sandra P. D’Angelo, et al. “Safety and efficacy of PD-1 blockade using pembrolizumab in patients with advanced soft tissue (STS) and bone sarcomas (BS): Results of SARC028—A multicenter phase II study.” In Journal of Clinical Oncology, 34:11006–11006. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.11006.Full Text
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Whitley, Melodi J., Diana M. Cardona, Dan G. Blazer, Shelley Hwang, Rachel A. Greenup, Paul J. Mosca, Joan Cahill, et al. “Abstract SY36-03: Intraoperative molecular imaging with protease-activated fluorescent imaging agents.” In Cancer Research, Vol. 75. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.am2015-sy36-03.Full Text
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Attia, Steven, Richard F. Riedel, Steven Ian Robinson, Robert Martin Conry, Kamalesh Kumar Sankhala, Ben K. Seon, Delia Alvarez, Bonne J. Adams, Charles P. Theuer, and Robert G. Maki. “A phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) in combination with pazopanib in patients with advanced soft tissue sarcoma (STS).” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.Link to Item
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Burgess, Melissa Amber, John Crowley, Denise K. Reinke, Richard F. Riedel, Suzanne George, Sujana Movva, Brian Andrew Van Tine, et al. “SARC 028: A phase II study of the anti-PD1 antibody pembrolizumab (P) in patients (Pts) with advanced sarcomas.” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.Link to Item
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Whitley, M. J., D. M. Cardona, D. G. Blazer, E. Hwang, R. A. Greenup, P. J. Mosca, J. Cahill, et al. “A Phase I Clinical Trial of LUM015: A Protease-activated Fluorescent Imaging Agent to Detect Cancer during Surgery.” In Annals of Surgical Oncology, 22:S11–12. SPRINGER, 2015.Link to Item
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Whitley, Melodi Javid, Diana M. Cardona, Dan G. Blazer, Shelley E. Hwang, Paul J. Mosca, Joan Cahill, Jorge M. Ferrer, et al. “A phase I study of the safety and activation of a cathepsin-activatable fluorescent cancer-specific probe LUM015.” In Journal of Clinical Oncology, 32:TPS11135–TPS11135. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.tps11135.Full Text
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LeBlanc, Thomas William, James A. Tulsky, Amy Pickar Abernethy, Christopher A. Jones, Anthony N. Galanos, and Richard F. Riedel. “Oncologists' perceptions of rounding alongside palliative care physicians: Results of a post-intervention survey study.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Jones, Christopher, Richard Riedel, Kim Slusser, Devi Desai, and Anthony Galanos. “Sharing the Sandbox: Implementation and Results From a Fully Integrated Palliative Care/Medical Oncology Rounding Model for Inpatient Cancer Care (SA512).” In Journal of Pain and Symptom Management, 45:400–401. Elsevier BV, 2013. https://doi.org/10.1016/j.jpainsymman.2012.10.256.Full Text
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Blay, Jean-Yves, Sant P. Chawla, Isabelle Ray-Coquard, Axel Le Cesne, Arthur P. Staddon, Mohammed M. Milhem, Nicolas Penel, et al. “Phase III, placebo-controlled trial (SUCCEED) evaluating ridaforolimus as maintenance therapy in advanced sarcoma patients following clinical benefit from prior standard cytotoxic chemotherapy: Long-term (>= 24 months) overall survival results.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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Howard, L. A., K. E. Bullock, J. C. Bendell, H. E. Uronis, G. Vlahovic, G. C. Blobe, R. F. Riedel, A. B. Nixon, J. P. Gockerman, and H. I. Hurwitz. “Bevacizumab (B) plus everolimus (E) and panitumumab (P) in refractory advanced solid tumors.” In Journal of Clinical Oncology, Vol. 27. AMER SOC CLINICAL ONCOLOGY, 2009.Link to Item
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Riedel, R. F., A. Porrello, E. Chenette, A. Potti, J. R. Nevins, and P. G. Febbo. “A genomic approach to identify mechanisms associated with chemotherapy resistance.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Riedel, R. F., P. G. Febbo, and J. Crawford. “IDENTIFYING MECHANISMS OF RESISTANCE IN PATIENTS WITH LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER RECEIVING DOSE-DENSE NEOADJUVANT/INDUCTION CHEMOTHERAPY.” In Journal of Investigative Medicine, 55:S282–S282. SAGE Publications, 2007. https://doi.org/10.1097/00042871-200701010-00730.Full Text
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- Teaching & Mentoring
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Recent Courses
- MEDICINE 425C: Clinical Coagulation 2023
- MEDICINE 438C: Clinical Hematology and Oncology Consults (Duke or Durham VA) 2023
- MEDICINE 402C: Medical Sub-Internship in Hematology-Oncology 2022
- MEDICINE 425C: Clinical Coagulation 2022
- MEDICINE 434C: Outpatient Hematology-Oncology (Duke or Durham VA) 2022
- MEDICINE 438C: Clinical Hematology and Oncology Consults (Duke or Durham VA) 2022
- MEDICINE 402C: Medical Sub-Internship in Hematology-Oncology 2021
- MEDICINE 425C: Clinical Coagulation 2021
- MEDICINE 434C: Outpatient Hematology-Oncology (Duke or Durham VA) 2021
- MEDICINE 438C: Clinical Hematology and Oncology Consults (Duke or Durham VA) 2021
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