Scholars@Duke
Joseph Linton Roberts

Joseph Linton Roberts

Professor Emeritus of Pediatrics
Pediatrics, Allergy and Immunology
rober060@mc.duke.edu
Box 2898 Med Ctr, Durham, NC 27710
Room 101B MSRB1, Duke University Medical Center, Durham, NC 27710

Scholarly Works - Conferences

Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency.

Conference J Clin Invest · July 2, 2018 Ikaros/IKZF1 is an essential transcription factor expressed throughout hematopoiesis. IKZF1 is implicated in lymphocyte and myeloid differentiation and negative regulation of cell proliferation. In humans, somatic mutations in IKZF1 have been linked to the ... Full text Link to item Cite