Scholars@Duke

Academic Articles

• Wang, Virginia, Cynthia J. Coffman, Ann M. O’Hare, and Matthew L. Maciejewski. “Authors' Reply.” J Am Soc Nephrol 30, no. 7 (July 2019): 1338–39. https://doi.org/10.1681/ASN.2019040402.
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• Pun, Patrick H., Matthew E. Dupre, Clark Tyson, Sana M. Al-Khatib, and Christopher B. Granger. “Authors' Reply.” J Am Soc Nephrol 30, no. 6 (June 2019): 1137–38. https://doi.org/10.1681/ASN.2019040353.
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• Dragani, Tommaso A., Francesca Colombo, Elizabeth N. Pavlisko, and Victor L. Roggli. “Response to comments on 'Malignant mesothelioma diagnosed at a younger age is associated with heavier asbestos exposure' by Farioli et al. and Oddone et al.” Carcinogenesis 40, no. 3 (May 14, 2019): 490–91. https://doi.org/10.1093/carcin/bgy145.
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• Califf, Robert M. “Improving Clinical Outcomes in the Era of Information Ubiquity.” J Am Soc Nephrol 30, no. 1 (January 2019): 7–12. https://doi.org/10.1681/ASN.2018111128.
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• Warraich, Haider J., and Robert M. Califf. “Differences in Health Outcomes between Men and Women: Biological, Behavioral, and Societal Factors.” Clin Chem 65, no. 1 (January 2019): 19–23. https://doi.org/10.1373/clinchem.2018.287334.
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• Califf, Robert M. “Future of Personalized Cardiovascular Medicine: JACC State-of-the-Art Review.” J Am Coll Cardiol 72, no. 25 (December 25, 2018): 3301–9. https://doi.org/10.1016/j.jacc.2018.09.079.
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• Yang, Ju Dong, Manal F. Abdelmalek, Cynthia D. Guy, Anna Mae Diehl, and Ayako Suzuki. “Reply.” Clin Gastroenterol Hepatol 16, no. 10 (October 2018): 1684. https://doi.org/10.1016/j.cgh.2017.05.003.
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• Califf, Robert M., and Frank E. Harrell. “Individual risk prediction using data beyond the medical clinic.” Cmaj 190, no. 32 (August 13, 2018): E947–48. https://doi.org/10.1503/cmaj.180967.
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• Aronson, Solomon. “In Response.” Anesthesia and Analgesia 127, no. 1 (July 2018): 317–18. https://doi.org/10.1213/ane.0000000000003402.
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• Califf, Robert M. “Mass Customization, Ubiquitous Information, and Improvements to Health Outcomes in the United States.” Jama Cardiol 3, no. 5 (May 1, 2018): 365–66. https://doi.org/10.1001/jamacardio.2017.5354.
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• Partin, Melissa R., Aasma Shaukat, David B. Nelson, Amy Gravely, Sean Nugent, Ziad F. Gellad, and James F. Burgess. “Reply.” Clin Gastroenterol Hepatol 14, no. 3 (March 2016): 486. https://doi.org/10.1016/j.cgh.2015.12.008.
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• Selker, Harry P., John B. Buse, Robert M. Califf, Robert Carter, Dan M. Cooper, Jonathan Davis, Daniel E. Ford, et al. “CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes.” Clin Transl Sci 8, no. 6 (December 2015): 623–31. https://doi.org/10.1111/cts.12306.
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• Preiss, David, Laine E. Thomas, Daniel M. Wojdyla, Steven M. Haffner, Jason M. R. Gill, Thomas Yates, Melanie J. Davies, et al. “Prospective relationships between body weight and physical activity: an observational analysis from the NAVIGATOR study.” Bmj Open 5, no. 8 (August 14, 2015): e007901. https://doi.org/10.1136/bmjopen-2015-007901.
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• Kelly, Jacob P., Robert J. Mentz, Vic Hasselblad, Justin A. Ezekowitz, Paul W. Armstrong, Faiez Zannad, G Michael Felker, Robert M. Califf, Christopher M. O’Connor, and Adrian F. Hernandez. “Worsening heart failure during hospitalization for acute heart failure: Insights from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF).” Am Heart J 170, no. 2 (August 2015): 298–305. https://doi.org/10.1016/j.ahj.2015.04.007.
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• Khazanie, Prateeti, Gretchen M. Heizer, Vic Hasselblad, Paul W. Armstrong, Robert M. Califf, Justin Ezekowitz, Kenneth Dickstein, et al. “Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models.” Am Heart J 170, no. 2 (August 2015): 290–97. https://doi.org/10.1016/j.ahj.2015.04.006.
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• Maaten, Jozine M. ter, Allison M. Dunning, Mattia A. E. Valente, Kevin Damman, Justin A. Ezekowitz, Robert M. Califf, Randall C. Starling, et al. “Diuretic response in acute heart failure-an analysis from ASCEND-HF.” Am Heart J 170, no. 2 (August 2015): 313–21. https://doi.org/10.1016/j.ahj.2015.05.003.
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• Yates, T., M. J. Davies, S. M. Haffner, P. J. Schulte, L. Thomas, K. M. Huffman, C. W. Bales, et al. “Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial.” Diabet Med 32, no. 8 (August 2015): 1090–96. https://doi.org/10.1111/dme.12762.
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• Cannon, Christopher P., Michael A. Blazing, Robert P. Giugliano, Amy McCagg, Jennifer A. White, Pierre Theroux, Harald Darius, et al. “Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.” N Engl J Med 372, no. 25 (June 18, 2015): 2387–97. https://doi.org/10.1056/NEJMoa1410489.
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• Washam, Jeffrey B., Susanna R. Stevens, Yuliya Lokhnygina, Jonathan L. Halperin, Günter Breithardt, Daniel E. Singer, Kenneth W. Mahaffey, et al. “Digoxin use in patients with atrial fibrillation and adverse cardiovascular outcomes: a retrospective analysis of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF).” Lancet 385, no. 9985 (June 13, 2015): 2363–70. https://doi.org/10.1016/S0140-6736(14)61836-5.
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• Anderson, Monique L., Robert M. Califf, Jeremy Sugarman, and Jeremy participants in the NIH Health Care Systems Research Collaboratory Cluster Randomized Trial Workshop. “Ethical and regulatory issues of pragmatic cluster randomized trials in contemporary health systems.” Clinical Trials (London, England) 12, no. 3 (June 2015): 276–86. https://doi.org/10.1177/1740774515571140.
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• Roe, Matthew T., Kenneth W. Mahaffey, Justin A. Ezekowitz, John H. Alexander, Shaun G. Goodman, Adrian Hernandez, Tracy Temple, et al. “The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations.” Am Heart J 169, no. 6 (June 2015): 743–50. https://doi.org/10.1016/j.ahj.2015.03.002.
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• Eapen, Zubin J., Lisa A. McCoy, Gregg C. Fonarow, Clyde W. Yancy, Marie Lynn Miranda, Eric D. Peterson, Robert M. Califf, and Adrian F. Hernandez. “Utility of socioeconomic status in predicting 30-day outcomes after heart failure hospitalization.” Circ Heart Fail 8, no. 3 (May 2015): 473–80. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001879.
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• Fordyce, Christopher B., Matthew T. Roe, Tariq Ahmad, Peter Libby, Jeffrey S. Borer, William R. Hiatt, Michael R. Bristow, et al. “Cardiovascular drug development: is it dead or just hibernating?” J Am Coll Cardiol 65, no. 15 (April 21, 2015): 1567–82. https://doi.org/10.1016/j.jacc.2015.03.016.
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• Bethel, M. A., J. B. Green, J. Milton, A. Tajar, S. S. Engel, R. M. Califf, R. R. Holman, and R. R. TECOS Executive Committee. “Regional, age and sex differences in baseline characteristics of patients enrolled in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS).” Diabetes, Obesity & Metabolism 17, no. 4 (April 2015): 395–402. https://doi.org/10.1111/dom.12441.
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• Mark, D. B., P. Hodgson, J. Anuels, and R. M. Califf. “Transitions at the american heart journal.” Am Heart J 169, no. 4 (April 2015): 445. https://doi.org/10.1016/j.ahj.2015.02.013.
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• Anderson, Monique L., Karen Chiswell, Eric D. Peterson, Asba Tasneem, James Topping, and Robert M. Califf. “Compliance with results reporting at ClinicalTrials.gov.” N Engl J Med 372, no. 11 (March 12, 2015): 1031–39. https://doi.org/10.1056/NEJMsa1409364.
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• Bloomfield, Gerald S., Tracy Y. Wang, L Ebony Boulware, Robert M. Califf, Adrian F. Hernandez, Eric J. Velazquez, Eric D. Peterson, and Jennifer S. Li. “Implementation of management strategies for diabetes and hypertension: from local to global health in cardiovascular diseases.” Glob Heart 10, no. 1 (March 2015): 31–38. https://doi.org/10.1016/j.gheart.2014.12.010.
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• Katz, Marcelo, Robert M. Califf, Jie-Lena Sun, John J. V. McMurray, Laine Thomas, and Renato D. Lopes. “Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial.” Am J Med 128, no. 3 (March 2015): 297–302. https://doi.org/10.1016/j.amjmed.2014.08.022.
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• Lam, Carolyn S. P., Margaret McEntegart, Brian Claggett, Jiankang Liu, Hicham Skali, Eldrin Lewis, Lars Køber, et al. “Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the Valsartan in Acute Myocardial Infarction Trial (VALIANT).” European Journal of Heart Failure 17, no. 3 (March 2015): 301–12. https://doi.org/10.1002/ejhf.238.
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• Spratt, Susan E., Bryan C. Batch, Lisa P. Davis, Ashley A. Dunham, Michele Easterling, Mark N. Feinglos, Bradi B. Granger, et al. “Methods and initial findings from the Durham Diabetes Coalition: Integrating geospatial health technology and community interventions to reduce death and disability.” J Clin Transl Endocrinol 2, no. 1 (March 2015): 26–36. https://doi.org/10.1016/j.jcte.2014.10.006.
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• Califf, Robert M. “LCZ696: too good to be true?” Eur Heart J 36, no. 7 (February 14, 2015): 410–12. https://doi.org/10.1093/eurheartj/ehu501.
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• Halim, Sharif A., Megan L. Neely, Karen S. Pieper, Svati H. Shah, William E. Kraus, Elizabeth R. Hauser, Robert M. Califf, Christopher B. Granger, and L Kristin Newby. “Simultaneous consideration of multiple candidate protein biomarkers for long-term risk for cardiovascular events.” Circ Cardiovasc Genet 8, no. 1 (February 2015): 168–77. https://doi.org/10.1161/CIRCGENETICS.113.000490.
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• Putera, Martin, Robin Roark, Renato D. Lopes, Krishna Udayakumar, Eric D. Peterson, Robert M. Califf, and Bimal R. Shah. “Translation of acute coronary syndrome therapies: from evidence to routine clinical practice.” American Heart Journal 169, no. 2 (February 2015): 266–73. https://doi.org/10.1016/j.ahj.2014.09.015.
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• Koshizaka, Masaya, Renato D. Lopes, Eric M. Reyes, C Michael Gibson, Phillip J. Schulte, Gail E. Hafley, Adrian F. Hernandez, et al. “Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: results from the Project of Ex-vivo Vein Graft Engineering via Transfection IV trial.” Am Heart J 169, no. 1 (January 2015): 175–84. https://doi.org/10.1016/j.ahj.2014.10.013.
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• Tang, WH Wilson, Matthias Dupont, Adrian F. Hernandez, Adriaan A. Voors, Amy P. Hsu, G Michael Felker, Javed Butler, et al. “Comparative assessment of short-term adverse events in acute heart failure with cystatin C and other estimates of renal function: results from the ASCEND-HF trial.” Jacc Heart Fail 3, no. 1 (January 2015): 40–49. https://doi.org/10.1016/j.jchf.2014.06.014.
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• Van Wagoner, David R., Jonathan P. Piccini, Christine M. Albert, Mark E. Anderson, Emelia J. Benjamin, Bianca Brundel, Robert M. Califf, et al. “Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013.” Heart Rhythm 12, no. 1 (January 2015): e5–29. https://doi.org/10.1016/j.hrthm.2014.11.011.
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• Diepen, Sean van, Mohua Podder, Adrian F. Hernandez, Cynthia M. Westerhout, Paul W. Armstong, John J. V. McMurray, Zubin J. Eapen, et al. “Acute decompensated heart failure patients admitted to critical care units: insights from ASCEND-HF.” Int J Cardiol 177, no. 3 (December 20, 2014): 840–46. https://doi.org/10.1016/j.ijcard.2014.11.007.
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• Breithardt, Günter, Helmut Baumgartner, Scott D. Berkowitz, Anne S. Hellkamp, Jonathan P. Piccini, Susanna R. Stevens, Yuliya Lokhnygina, et al. “Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial.” Eur Heart J 35, no. 47 (December 14, 2014): 3377–85. https://doi.org/10.1093/eurheartj/ehu305.
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• Califf, Robert M. “Commentary on Vickers.” Clin Trials 11, no. 6 (December 2014): 626–27. https://doi.org/10.1177/1740774514553485.
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• Preiss, D., S. M. Haffner, L. E. Thomas, J. -. L. Sun, N. Sattar, T. Yates, M. J Davies, et al. “Change in levels of physical activity after diagnosis of type 2 diabetes: an observational analysis from the NAVIGATOR study.” Diabetes Obes Metab 16, no. 12 (December 2014): 1265–68. https://doi.org/10.1111/dom.12320.
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• Park, Duk-Woo, Robert M. Clare, Phillip J. Schulte, Karen S. Pieper, Linda K. Shaw, Robert M. Califf, E Magnus Ohman, et al. “Extent, location, and clinical significance of non-infarct-related coronary artery disease among patients with ST-elevation myocardial infarction.” Jama 312, no. 19 (November 19, 2014): 2019–27. https://doi.org/10.1001/jama.2014.15095.
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• Patel, Priyesh A., Gretchen Heizer, Christopher M. O’Connor, Phillip J. Schulte, Kenneth Dickstein, Justin A. Ezekowitz, Paul W. Armstrong, et al. “Hypotension during hospitalization for acute heart failure is independently associated with 30-day mortality: findings from ASCEND-HF.” Circ Heart Fail 7, no. 6 (November 2014): 918–25. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000872.
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• Thomas, Kevin L., Bimal R. Shah, Sharon Elliot-Bynum, Kristin D. Thomas, Katrina Damon, Nancy M. Allen LaPointe, Sarah Calhoun, et al. “Check it, change it: a community-based, multifaceted intervention to improve blood pressure control.” Circ Cardiovasc Qual Outcomes 7, no. 6 (November 2014): 828–34. https://doi.org/10.1161/CIRCOUTCOMES.114.001039.
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• Hess, Connie N., Renato D. Lopes, C Michael Gibson, Rebecca Hager, Daniel M. Wojdyla, Brian R. Englum, Michael J. Mack, et al. “Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV.” Circulation 130, no. 17 (October 21, 2014): 1445–51. https://doi.org/10.1161/CIRCULATIONAHA.113.008193.
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• Barros e Silva, Pedro G. M. de, Robert M. Califf, Jie-Lena Sun, John J. V. McMurray, Rury Holman, Steven Haffner, Laine Thomas, and Renato D. Lopes. “Chronic obstructive pulmonary disease and cardiovascular risk: insights from the NAVIGATOR trial.” Int J Cardiol 176, no. 3 (October 20, 2014): 1126–28. https://doi.org/10.1016/j.ijcard.2014.07.297.
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• Califf, Robert M. “Patient-centered outcomes composites: a glimpse of the future.” Circulation 130, no. 15 (October 7, 2014): 1223–24. https://doi.org/10.1161/CIRCULATIONAHA.114.013135.
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• Deursen, Vincent M. van, Adrian F. Hernandez, Amanda Stebbins, Vic Hasselblad, Justin A. Ezekowitz, Robert M. Califf, Stephen S. Gottlieb, et al. “Nesiritide, renal function, and associated outcomes during hospitalization for acute decompensated heart failure: results from the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF).” Circulation 130, no. 12 (September 16, 2014): 958–65. https://doi.org/10.1161/CIRCULATIONAHA.113.003046.
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• Hess, Paul L., Michael J. Mirro, Hans-Christoph Diener, John W. Eikelboom, Sana M. Al-Khatib, Elaine M. Hylek, Hayden B. Bosworth, et al. “Addressing barriers to optimal oral anticoagulation use and persistence among patients with atrial fibrillation: Proceedings, Washington, DC, December 3-4, 2012.” Am Heart J 168, no. 3 (September 2014): 239-247.e1. https://doi.org/10.1016/j.ahj.2014.04.007.
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• Holman, Rury R., Harald Sourij, and Robert M. Califf. “Cardiovascular outcome trials of glucose-lowering strategies in type 2 diabetes--Authors' reply.” Lancet (London, England) 384, no. 9948 (September 2014): 1097–98. https://doi.org/10.1016/s0140-6736(14)61674-3.
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• Bernardez-Pereira, Sabrina, Renato D. Lopes, Maria Julia Machline Carrion, Eliana Vieira Santucci, Rafael Marques Soares, Matheus de Oliveira Abreu, Ligia Nasi Laranjeira, et al. “Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: insights from the ClinicalTrials.gov registry.” Am Heart J 168, no. 2 (August 2014): 213-9.e1. https://doi.org/10.1016/j.ahj.2014.04.013.
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• Blazing, Michael A., Robert P. Giugliano, Christopher P. Cannon, Thomas A. Musliner, Andrew M. Tershakovec, Jennifer A. White, Craig Reist, Amy McCagg, Eugene Braunwald, and Robert M. Califf. “Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18,144 patients after acute coronary syndromes: final baseline characteristics of the IMPROVE-IT study population.” Am Heart J 168, no. 2 (August 2014): 205-12.e1. https://doi.org/10.1016/j.ahj.2014.05.004.
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• Califf, Robert M. “The new era of clinical research: using data for multiple purposes.” Am Heart J 168, no. 2 (August 2014): 133–34. https://doi.org/10.1016/j.ahj.2014.04.014.
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• Girgis, I. G., M. R. Patel, G. R. Peters, K. T. Moore, K. W. Mahaffey, C. C. Nessel, J. L. Halperin, R. M. Califf, K. A. A. Fox, and R. C. Becker. “Population pharmacokinetics and pharmacodynamics of rivaroxaban in patients with non-valvular atrial fibrillation: results from ROCKET AF.” J Clin Pharmacol 54, no. 8 (August 2014): 917–27. https://doi.org/10.1002/jcph.288.
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• Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, Colleen M. Brophy, Michael J. Mack, Eric D. Peterson, Judson B. Williams, et al. “Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial.” Jama Surg 149, no. 8 (August 2014): 798–805. https://doi.org/10.1001/jamasurg.2014.87.
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• Hess, Connie N., Matthew T. Roe, C Michael Gibson, Robert J. Temple, Michael J. Pencina, Deborah A. Zarin, Kevin J. Anstrom, et al. “Independent data monitoring committees: preparing a path for the future.” Am Heart J 168, no. 2 (August 2014): 135-41.e1. https://doi.org/10.1016/j.ahj.2014.05.003.
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• Piccini, Jonathan P., Jyotsna Garg, Manesh R. Patel, Yuliya Lokhnygina, Shaun G. Goodman, Richard C. Becker, Scott D. Berkowitz, et al. “Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial.” Eur Heart J 35, no. 28 (July 21, 2014): 1873–80. https://doi.org/10.1093/eurheartj/ehu083.
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• Halperin, Jonathan L., Graeme J. Hankey, Daniel M. Wojdyla, Jonathan P. Piccini, Yuliya Lokhnygina, Manesh R. Patel, Günter Breithardt, et al. “Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF).” Circulation 130, no. 2 (July 8, 2014): 138–46. https://doi.org/10.1161/CIRCULATIONAHA.113.005008.
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• Fleurence, Rachael L., Lesley H. Curtis, Robert M. Califf, Richard Platt, Joe V. Selby, and Jeffrey S. Brown. “Launching PCORnet, a national patient-centered clinical research network.” J Am Med Inform Assoc 21, no. 4 (July 2014): 578–82. https://doi.org/10.1136/amiajnl-2014-002747.
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• Sugarman, Jeremy, and Robert M. Califf. “Ethics and regulatory complexities for pragmatic clinical trials.” Jama 311, no. 23 (June 18, 2014): 2381–82. https://doi.org/10.1001/jama.2014.4164.
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• Holman, Rury R., Harald Sourij, and Robert M. Califf. “Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes.” Lancet 383, no. 9933 (June 7, 2014): 2008–17. https://doi.org/10.1016/S0140-6736(14)60794-7.
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• Hill, Kevin D., Karen Chiswell, Robert M. Califf, Gail Pearson, and Jennifer S. Li. “Characteristics of pediatric cardiovascular clinical trials registered on ClinicalTrials.gov.” Am Heart J 167, no. 6 (June 2014): 921-9.e2. https://doi.org/10.1016/j.ahj.2014.02.002.
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• Steinberg, Benjamin A., Anne S. Hellkamp, Yuliya Lokhnygina, Jonathan L. Halperin, Günter Breithardt, Rod Passman, Graeme J. Hankey, et al. “Use and outcomes of antiarrhythmic therapy in patients with atrial fibrillation receiving oral anticoagulation: results from the ROCKET AF trial.” Heart Rhythm 11, no. 6 (June 2014): 925–32. https://doi.org/10.1016/j.hrthm.2014.03.006.
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• Vemulapalli, Sreekanth, Jamy Ard, George L. Bakris, Deepak L. Bhatt, Alan S. Brown, William C. Cushman, Keith C. Ferdinand, et al. “Proceedings from Duke resistant hypertension think tank.” Am Heart J 167, no. 6 (June 2014): 775-88.e1. https://doi.org/10.1016/j.ahj.2014.02.008.
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• Wong, Ka Sing Lawrence, Dai Yi Hu, Abraham Oomman, Ru-San Tan, Manesh R. Patel, Daniel E. Singer, Günter Breithardt, et al. “Rivaroxaban for stroke prevention in East Asian patients from the ROCKET AF trial.” Stroke 45, no. 6 (June 2014): 1739–47. https://doi.org/10.1161/STROKEAHA.113.002968.
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• Sherwood, Matthew W., James D. Douketis, Manesh R. Patel, Jonathan P. Piccini, Anne S. Hellkamp, Yuliya Lokhnygina, Alex C. Spyropoulos, et al. “Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF).” Circulation 129, no. 18 (May 6, 2014): 1850–59. https://doi.org/10.1161/CIRCULATIONAHA.113.005754.
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• Califf, Robert M. “The Patient-Centered Outcomes Research Network: a national infrastructure for comparative effectiveness research.” N C Med J 75, no. 3 (May 2014): 204–10. https://doi.org/10.18043/ncm.75.3.204.
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• Hankey, Graeme J., Susanna R. Stevens, Jonathan P. Piccini, Yuliya Lokhnygina, Kenneth W. Mahaffey, Jonathan L. Halperin, Manesh R. Patel, et al. “Intracranial hemorrhage among patients with atrial fibrillation anticoagulated with warfarin or rivaroxaban: the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation.” Stroke 45, no. 5 (May 2014): 1304–12. https://doi.org/10.1161/STROKEAHA.113.004506.
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• Inrig, Jula K., Robert M. Califf, Asba Tasneem, Radha K. Vegunta, Christopher Molina, John W. Stanifer, Karen Chiswell, and Uptal D. Patel. “The landscape of clinical trials in nephrology: a systematic review of Clinicaltrials.gov.” Am J Kidney Dis 63, no. 5 (May 2014): 771–80. https://doi.org/10.1053/j.ajkd.2013.10.043.
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• Kalogeropoulos, Andreas P., WH Wilson Tang, Amy Hsu, G Michael Felker, Adrian F. Hernandez, Richard W. Troughton, Adriaan A. Voors, et al. “High-sensitivity C-reactive protein in acute heart failure: insights from the ASCEND-HF trial.” J Card Fail 20, no. 5 (May 2014): 319–26. https://doi.org/10.1016/j.cardfail.2014.02.002.
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• Kunadian, Vijay, Robert P. Giugliano, L Kristin Newby, Cafer Zorkun, Jianping Guo, Akshay Bagai, Gilles Montalescot, et al. “Angiographic outcomes with early eptifibatide therapy in non-ST-segment elevation acute coronary syndrome (from the EARLY ACS Trial).” Am J Cardiol 113, no. 8 (April 15, 2014): 1297–1305. https://doi.org/10.1016/j.amjcard.2014.01.404.
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• Huffman, Kim M., Jie-Lena Sun, Laine Thomas, Connie W. Bales, Robert M. Califf, Thomas Yates, Melanie J. Davies, et al. “Impact of baseline physical activity and diet behavior on metabolic syndrome in a pharmaceutical trial: results from NAVIGATOR.” Metabolism: Clinical and Experimental 63, no. 4 (April 2014): 554–61. https://doi.org/10.1016/j.metabol.2014.01.002.
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• Lewis, Eldrin F., Yanhong Li, Marc A. Pfeffer, Scott D. Solomon, Kevin P. Weinfurt, Eric J. Velazquez, Robert M. Califf, et al. “Impact of cardiovascular events on change in quality of life and utilities in patients after myocardial infarction: a VALIANT study (valsartan in acute myocardial infarction).” Jacc Heart Fail 2, no. 2 (April 2014): 159–65. https://doi.org/10.1016/j.jchf.2013.12.003.
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• Yates, Thomas, Steven M. Haffner, Phillip J. Schulte, Laine Thomas, Kim M. Huffman, Connie W. Bales, Robert M. Califf, et al. “Association between change in daily ambulatory activity and cardiovascular events in people with impaired glucose tolerance (NAVIGATOR trial): a cohort analysis.” Lancet 383, no. 9922 (March 22, 2014): 1059–66. https://doi.org/10.1016/S0140-6736(13)62061-9.
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• Goodman, Shaun G., Daniel M. Wojdyla, Jonathan P. Piccini, Harvey D. White, John F. Paolini, Christopher C. Nessel, Scott D. Berkowitz, et al. “Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation).” J Am Coll Cardiol 63, no. 9 (March 11, 2014): 891–900. https://doi.org/10.1016/j.jacc.2013.11.013.
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• Califf, Robert M. “Large simple trials: really, it can't be that simple!.” Eur Heart J 35, no. 9 (March 2014): 549–51. https://doi.org/10.1093/eurheartj/eht556.
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• De Ferrari, Gaetano M., Keith A. A. Fox, Jennifer A. White, Robert P. Giugliano, Pierluigi Tricoci, Harmony R. Reynolds, Judith S. Hochman, et al. “Outcomes among non-ST-segment elevation acute coronary syndromes patients with no angiographically obstructive coronary artery disease: observations from 37,101 patients.” Eur Heart J Acute Cardiovasc Care 3, no. 1 (March 2014): 37–45. https://doi.org/10.1177/2048872613489315.
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• Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, W Schuyler Jones, Judson B. Williams, Michael J. Mack, Eric D. Peterson, et al. “Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery.” Ann Thorac Surg 97, no. 3 (March 2014): 824–30. https://doi.org/10.1016/j.athoracsur.2013.09.099.
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• Califf, R. M. “Integrated efficacy to effectiveness trials.” Clinical Pharmacology and Therapeutics 95, no. 2 (February 2014): 131–33. https://doi.org/10.1038/clpt.2013.232.
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• Fleurence, R. L., L. H. Curtis, R. M. Califf, R. Platt, J. V. Selby, and J. S. Brown. “Launching PCORnet, a national patient-centered clinical research network.” Journal of the American Medical Informatics Association 21, no. 4 (January 1, 2014): 578–82. https://doi.org/10.1136/amiajnl-2014-002747.
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• Holman, R. R., H. Sourij, and R. M. Califf. “Erratum: Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes (Lancet (2014) 383 (2008-17)).” The Lancet 383, no. 9936 (January 1, 2014): 2212. https://doi.org/10.1016/S0140-6736(14)61084-9.
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• Jones, William Schuyler, Anne S. Hellkamp, Jonathan Halperin, Jonathan P. Piccini, Gunter Breithardt, Daniel E. Singer, Keith A. A. Fox, et al. “Efficacy and safety of rivaroxaban compared with warfarin in patients with peripheral artery disease and non-valvular atrial fibrillation: insights from ROCKET AF.” Eur Heart J 35, no. 4 (January 2014): 242–49. https://doi.org/10.1093/eurheartj/eht492.
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• Mahaffey, Kenneth W., Susanna R. Stevens, Harvey D. White, Christopher C. Nessel, Shaun G. Goodman, Jonathan P. Piccini, Manesh R. Patel, et al. “Ischaemic cardiac outcomes in patients with atrial fibrillation treated with vitamin K antagonism or factor Xa inhibition: results from the ROCKET AF trial.” Eur Heart J 35, no. 4 (January 2014): 233–41. https://doi.org/10.1093/eurheartj/eht428.
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• Vo-Dinh, T., A. Mahadevan-Jansen, and W. S. Grundfest. “Introduction.” Progress in Biomedical Optics and Imaging  Proceedings of Spie 8935 (January 1, 2014).
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• Shen, Lan, Bimal R. Shah, Eric M. Reyes, Laine Thomas, Daniel Wojdyla, Peter Diem, Lawrence A. Leiter, et al. “Role of diuretics, β blockers, and statins in increasing the risk of diabetes in patients with impaired glucose tolerance: reanalysis of data from the NAVIGATOR study.” Bmj 347 (December 9, 2013): f6745. https://doi.org/10.1136/bmj.f6745.
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• Reith, Christina, Martin Landray, and Robert M. Califf. “Randomized clinical trials--removing obstacles.” N Engl J Med 369, no. 23 (December 5, 2013): 2269. https://doi.org/10.1056/NEJMc1312901.
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• Green, Jennifer B., M Angelyn Bethel, Sanjoy K. Paul, Arne Ring, Keith D. Kaufman, Deborah R. Shapiro, Robert M. Califf, and Rury R. Holman. “Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease.” Am Heart J 166, no. 6 (December 2013): 983-989.e7. https://doi.org/10.1016/j.ahj.2013.09.003.
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• Kaul, Padma, Shelby D. Reed, Adrian F. Hernandez, Jonathan G. Howlett, Justin A. Ezekowitz, Yanhong Li, Yinggan Zheng, et al. “Differences in treatment, outcomes, and quality of life among patients with heart failure in Canada and the United States.” Jacc Heart Fail 1, no. 6 (December 2013): 523–30. https://doi.org/10.1016/j.jchf.2013.07.004.
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• Richesson, Rachel L., Shelley A. Rusincovitch, Douglas Wixted, Bryan C. Batch, Mark N. Feinglos, Marie Lynn Miranda, W Ed Hammond, Robert M. Califf, and Susan E. Spratt. “A comparison of phenotype definitions for diabetes mellitus.” J Am Med Inform Assoc 20, no. e2 (December 2013): e319–26. https://doi.org/10.1136/amiajnl-2013-001952.
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• Richesson, Rachel L., W Ed Hammond, Meredith Nahm, Douglas Wixted, Gregory E. Simon, Jennifer G. Robinson, Alan E. Bauck, et al. “Electronic health records based phenotyping in next-generation clinical trials: a perspective from the NIH Health Care Systems Collaboratory.” J Am Med Inform Assoc 20, no. e2 (December 2013): e226–31. https://doi.org/10.1136/amiajnl-2013-001926.
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• Califf, Robert M., and Richard Platt. “Embedding cardiovascular research into practice.” Jama 310, no. 19 (November 20, 2013): 2037–38. https://doi.org/10.1001/jama.2013.282771.
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• Eggers, Kai M., Paul W. Armstrong, Robert M. Califf, Nina Johnston, Maarten L. Simoons, Per Venge, and Stefan K. James. “Clinical and prognostic implications of circulating pentraxin 3 levels in non ST-elevation acute coronary syndrome.” Clin Biochem 46, no. 16–17 (November 2013): 1655–59. https://doi.org/10.1016/j.clinbiochem.2013.08.014.
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• Latini, Roberto, Lidia Staszewsky, Jie-Lena Sun, M Angelyn Bethel, Marcello Disertori, Steven M. Haffner, Rury R. Holman, et al. “Incidence of atrial fibrillation in a population with impaired glucose tolerance: the contribution of glucose metabolism and other risk factors. A post hoc analysis of the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial.” Am Heart J 166, no. 5 (November 2013): 935-40.e1. https://doi.org/10.1016/j.ahj.2013.08.012.
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• Shah, Bimal R., Kevin L. Thomas, Sharon Elliot-Bynum, Kristin Thomas, Katrina Damon, Nancy Allen LaPointe, Sarah A. Calhoun, et al. “Check it, change it: a community-based intervention to improve blood pressure control.” Circ Cardiovasc Qual Outcomes 6, no. 6 (November 2013): 741–48. https://doi.org/10.1161/CIRCOUTCOMES.113.000148.
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• Armstrong, Paul W., and Robert M. Califf. “Data and safety monitoring boards: academic credit where credit is due?” Jama 310, no. 15 (October 16, 2013): 1563–64. https://doi.org/10.1001/jama.2013.280383.
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• Ezekowitz, Justin A., Jeffrey A. Bakal, Cynthia M. Westerhout, Robert P. Giugliano, Harvey White, Matyas Keltai, Dorairaj Prabhakaran, et al. “The relationship between meteorological conditions and index acute coronary events in a global clinical trial.” Int J Cardiol 168, no. 3 (October 3, 2013): 2315–21. https://doi.org/10.1016/j.ijcard.2013.01.061.
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• Kaul, Padma, Jean-François Tanguay, L Kristin Newby, Judith S. Hochman, Cynthia M. Westerhout, Robert M. Califf, Pierluigi Tricoci, et al. “Association between bleeding and mortality among women and men with high-risk acute coronary syndromes: insights from the Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes (EARLY ACS) trial.” Am Heart J 166, no. 4 (October 2013): 723–28. https://doi.org/10.1016/j.ahj.2013.07.014.
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• Piccini, Jonathan P., and Robert M. Califf. “Postmarket surveillance and returned product analysis: success but not transparency.” Heart Rhythm 10, no. 10 (October 2013): 1469–70. https://doi.org/10.1016/j.hrthm.2013.08.001.
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• Alexander, Karen P., David F. Kong, Aijing Z. Starr, Judith Kramer, Karen Chiswell, Asba Tasneem, and Robert M. Califf. “Portfolio of clinical research in adult cardiovascular disease as reflected in ClinicalTrials.gov.” J Am Heart Assoc 2, no. 5 (September 26, 2013): e000009. https://doi.org/10.1161/JAHA.113.000009.
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• Gottlieb, Stephen S., Amanda Stebbins, Adriaan A. Voors, Vic Hasselblad, Justin A. Ezekowitz, Robert M. Califf, Christopher M. O’Connor, Randall C. Starling, and Adrian F. Hernandez. “Effects of nesiritide and predictors of urine output in acute decompensated heart failure: results from ASCEND-HF (acute study of clinical effectiveness of nesiritide and decompensated heart failure).” J Am Coll Cardiol 62, no. 13 (September 24, 2013): 1177–83. https://doi.org/10.1016/j.jacc.2013.04.073.
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• Reith, Christina, Martin Landray, P. J. Devereaux, Jackie Bosch, Christopher B. Granger, Colin Baigent, Robert M. Califf, Rory Collins, and Salim Yusuf. “Randomized clinical trials--removing unnecessary obstacles.” N Engl J Med 369, no. 11 (September 12, 2013): 1061–65. https://doi.org/10.1056/NEJMsb1300760.
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• Lopes, Renato D., Jennifer A. White, Pierluigi Tricoci, Harvey D. White, Paul W. Armstrong, Eugene Braunwald, Robert P. Giugliano, et al. “Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: insights from the EARLY ACS trial.” Int J Cardiol 167, no. 6 (September 10, 2013): 2580–87. https://doi.org/10.1016/j.ijcard.2012.06.053.
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• Piccini, Jonathan P., Susanna R. Stevens, Yuchiao Chang, Daniel E. Singer, Yuliya Lokhnygina, Alan S. Go, Manesh R. Patel, et al. “Response to letter regarding article, "renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R2CHADS2 index in the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) study cohorts".” Circulation 128, no. 11 (September 10, 2013): e172–73. https://doi.org/10.1161/CIRCULATIONAHA.113.004013.
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• Alexander, John H., Elliott Levy, Jack Lawrence, Michael Hanna, Anthony P. Waclawski, Junyuan Wang, Robert M. Califf, Lars Wallentin, and Christopher B. Granger. “Documentation of study medication dispensing in a prospective large randomized clinical trial: experiences from the ARISTOTLE Trial.” Am Heart J 166, no. 3 (September 2013): 559–65. https://doi.org/10.1016/j.ahj.2013.05.025.
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• Bagai, Akshay, Jennifer A. White, Yuliya Lokhnygina, Robert P. Giugliano, Frans Van de Werf, Gilles Montalescot, Paul W. Armstrong, et al. “Routine early eptifibatide versus delayed provisional use at percutaneous coronary intervention in high-risk non-ST-segment elevation acute coronary syndromes patients: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome trial.” Am Heart J 166, no. 3 (September 2013): 466–73. https://doi.org/10.1016/j.ahj.2013.05.019.
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• Cai, Qiangjun, Nilay Mehta, Elena B. Sgarbossa, Sergio L. Pinski, Galen S. Wagner, Robert M. Califf, and Alejandro Barbagelata. “The left bundle-branch block puzzle in the 2013 ST-elevation myocardial infarction guideline: from falsely declaring emergency to denying reperfusion in a high-risk population. Are the Sgarbossa Criteria ready for prime time?” Am Heart J 166, no. 3 (September 2013): 409–13. https://doi.org/10.1016/j.ahj.2013.03.032.
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• Califf, Robert M., and Michael J. Pencina. “Predictive models in heart failure: who cares?” Circ Heart Fail 6, no. 5 (September 1, 2013): 877–78. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000659.
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• Gallin, Elaine K., Enriqueta Bond, Robert M. Califf, William F. Crowley, Pamela Davis, Richard Galbraith, and E Albert Reece. “Forging stronger partnerships between academic health centers and patient-driven organizations.” Acad Med 88, no. 9 (September 2013): 1220–24. https://doi.org/10.1097/ACM.0b013e31829ed2a7.
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• Hess, Connie N., Phillip J. Schulte, L Kristin Newby, Philippe Gabriel Steg, Anthony J. Dalby, Marc J. Schweiger, Basil S. Lewis, et al. “Duration of eptifibatide infusion after percutaneous coronary intervention and outcomes among high-risk patients with non-ST-segment elevation acute coronary syndrome: insights from EARLY ACS.” Eur Heart J Acute Cardiovasc Care 2, no. 3 (September 2013): 246–55. https://doi.org/10.1177/2048872612474922.
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• Howlett, Jonathan G., Justin A. Ezekowitz, Mohua Podder, Adrian F. Hernandez, Rafael Diaz, Kenneth Dickstein, Mark E. Dunlap, et al. “Global variation in quality of care among patients hospitalized with acute heart failure in an international trial: findings from the acute study clinical effectiveness of nesiritide in decompensated heart failure trial (ASCEND-HF).” Circ Cardiovasc Qual Outcomes 6, no. 5 (September 1, 2013): 534–42. https://doi.org/10.1161/CIRCOUTCOMES.113.000119.
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• Kimmel, Stephen E., Benjamin French, Jeffrey L. Anderson, Brian F. Gage, Julie A. Johnson, Yves D. Rosenberg, Nancy L. Geller, et al. “Rationale and design of the Clarification of Optimal Anticoagulation through Genetics trial.” Am Heart J 166, no. 3 (September 2013): 435–41. https://doi.org/10.1016/j.ahj.2013.04.009.
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• Miranda, Marie Lynn, Jeffrey Ferranti, Benjamin Strauss, Brian Neelon, and Robert M. Califf. “Geographic health information systems: a platform to support the 'triple aim'.” Health Aff (Millwood) 32, no. 9 (September 2013): 1608–15. https://doi.org/10.1377/hlthaff.2012.1199.
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• Preiss, David, Thomas D. Giles, Laine E. Thomas, Jie-Lena Sun, Steven M. Haffner, Rury R. Holman, Eberhard Standl, et al. “Predictors of stroke in patients with impaired glucose tolerance: results from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial.” Stroke 44, no. 9 (September 2013): 2590–93. https://doi.org/10.1161/STROKEAHA.113.001177.
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• Reed, Shelby D., Padma Kaul, Yanhong Li, Zubin J. Eapen, Linda Davidson-Ray, Kevin A. Schulman, Barry M. Massie, et al. “Medical resource use, costs, and quality of life in patients with acute decompensated heart failure: findings from ASCEND-HF.” J Card Fail 19, no. 9 (September 2013): 611–20. https://doi.org/10.1016/j.cardfail.2013.07.003.
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• Mahaffey, Kenneth W., and Robert M. Califf. “Atrial fibrillation: a spectrum of risk with a uniform treatment effect of novel anticoagulants?” Eur Heart J 34, no. 31 (August 2013): 2429–31. https://doi.org/10.1093/eurheartj/eht205.
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• Chan, Mark Y., Jie-Lena Sun, L Kristin Newby, Yuliya Lokhnygina, Harvey D. White, David J. Moliterno, Pierre Théroux, et al. “Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years.” Int J Cardiol 167, no. 2 (July 31, 2013): 548–54. https://doi.org/10.1016/j.ijcard.2012.01.065.
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• Tricoci, Pierluigi, Sergio Leonardi, Jennifer White, Harvey D. White, Paul W. Armstrong, Gilles Montalescot, Robert P. Giugliano, et al. “Cardiac troponin after percutaneous coronary intervention and 1-year mortality in non-ST-segment elevation acute coronary syndrome using systematic evaluation of biomarker trends.” J Am Coll Cardiol 62, no. 3 (July 16, 2013): 242–51. https://doi.org/10.1016/j.jacc.2013.04.043.
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• Bethel, M Angelyn, Antonio R. Chacra, Prakash Deedwania, Gregory R. Fulcher, Rury R. Holman, Trond Jenssen, Steven E. Kahn, et al. “A novel risk classification paradigm for patients with impaired glucose tolerance and high cardiovascular risk.” Am J Cardiol 112, no. 2 (July 15, 2013): 231–37. https://doi.org/10.1016/j.amjcard.2013.03.019.
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• Diepen, Sean van, Anne S. Hellkamp, Manesh R. Patel, Richard C. Becker, Günter Breithardt, Werner Hacke, Jonathan L. Halperin, et al. “Efficacy and safety of rivaroxaban in patients with heart failure and nonvalvular atrial fibrillation: insights from ROCKET AF.” Circ Heart Fail 6, no. 4 (July 2013): 740–47. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000212.
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• Eapen, Zubin J., Shelby D. Reed, Yanhong Li, Robb D. Kociol, Paul W. Armstrong, Randall C. Starling, John J. McMurray, et al. “Do countries or hospitals with longer hospital stays for acute heart failure have lower readmission rates?: Findings from ASCEND-HF.” Circ Heart Fail 6, no. 4 (July 2013): 727–32. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000265.
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• Mahaffey, Kenneth W., Anne S. Hellkamp, Manesh R. Patel, Karen L. Hannan, Kimberly Schwabe, Christopher C. Nessel, Scott D. Berkowitz, et al. “End of study transition from study drug to open-label vitamin K antagonist therapy: the ROCKET AF experience.” Circ Cardiovasc Qual Outcomes 6, no. 4 (July 2013): 470–78. https://doi.org/10.1161/CIRCOUTCOMES.113.000132.
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• Califf, Robert M., Jonathan McCall, and Robert A. Harrington. “Assessing research results in the medical literature: trust but verify.” Jama Intern Med 173, no. 12 (June 24, 2013): 1053–55. https://doi.org/10.1001/jamainternmed.2013.829.
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• Mahaffey, Kenneth W., Daniel Wojdyla, Graeme J. Hankey, Harvey D. White, Christopher C. Nessel, Jonathan P. Piccini, Manesh R. Patel, et al. “Clinical outcomes with rivaroxaban in patients transitioned from vitamin K antagonist therapy: a subgroup analysis of a randomized trial.” Ann Intern Med 158, no. 12 (June 18, 2013): 861–68. https://doi.org/10.7326/0003-4819-158-12-201306180-00003.
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• Anderson, Jeffrey L., Cynthia D. Adams, Elliott M. Antman, Charles R. Bridges, Robert M. Califf, Donald E. Casey, William E. Chavey, et al. “2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.” Circulation 127, no. 23 (June 11, 2013): e663–828. https://doi.org/10.1161/CIR.0b013e31828478ac.
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• Anderson, Jeffrey L., Cynthia D. Adams, Elliott M. Antman, Charles R. Bridges, Robert M. Califf, Donald E. Casey, William E. Chavey, et al. “2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.” J Am Coll Cardiol 61, no. 23 (June 11, 2013): e179–347. https://doi.org/10.1016/j.jacc.2013.01.014.
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• Hirsch, Bradford R., Robert M. Califf, Steven K. Cheng, Asba Tasneem, John Horton, Karen Chiswell, Kevin A. Schulman, David M. Dilts, and Amy P. Abernethy. “Characteristics of oncology clinical trials: insights from a systematic analysis of ClinicalTrials.gov.” Jama Intern Med 173, no. 11 (June 10, 2013): 972–79. https://doi.org/10.1001/jamainternmed.2013.627.
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• Chatterjee, Ranee, Laine Thomas, Laura Svetkey, Frederick L. Brancati, Robert M. Califf, and David Edelman. “Effects of changes in potassium with valsartan use on diabetes risk: Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial.” Am J Hypertens 26, no. 6 (June 2013): 723–26. https://doi.org/10.1093/ajh/hpt016.
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• Eapen, Zubin J., John P. Vavalle, Christopher B. Granger, Robert A. Harrington, Eric D. Peterson, and Robert M. Califf. “Rescuing clinical trials in the United States and beyond: a call for action.” Am Heart J 165, no. 6 (June 2013): 837–47. https://doi.org/10.1016/j.ahj.2013.02.003.
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• Piccini, Jonathan P., Jennifer A. White, Rajendra H. Mehta, Yuliya Lokhnygina, Sana M. Al-Khatib, Pierluigi Tricoci, Robert M. Califf, et al. “Response to letter regarding article, “sustained ventricular tachycardia and ventricular fibrillation complicating non–ST-segment elevation acute coronary syndromes”.” Circulation 127, no. 20 (May 21, 2013): e634. https://doi.org/10.1161/circulationaha.112.147546.
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• Piccini, Jonathan P., Susanna R. Stevens, Yuliya Lokhnygina, Manesh R. Patel, Jonathan L. Halperin, Daniel E. Singer, Graeme J. Hankey, et al. “Outcomes after cardioversion and atrial fibrillation ablation in patients treated with rivaroxaban and warfarin in the ROCKET AF trial.” J Am Coll Cardiol 61, no. 19 (May 14, 2013): 1998–2006. https://doi.org/10.1016/j.jacc.2013.02.025.
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• Rose, Jason J., L Kristin Newby, Samuel Broderick, Karen Chiswell, Frans Van de Werf, Paul W. Armstrong, Kenneth W. Mahaffey, et al. “Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes.” J Am Coll Cardiol 61, no. 13 (April 2, 2013): 1461–63. https://doi.org/10.1016/j.jacc.2012.12.032.
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• Berger, Peter B., Judson B. Williams, Vic Hasselblad, Karen Chiswell, Karen S. Pieper, and Robert M. Califf. “Would tirofiban have been shown non-inferior to abciximab had the TENACITY trial not been terminated for financial reasons?” J Interv Cardiol 26, no. 2 (April 2013): 123–30. https://doi.org/10.1111/j.1540-8183.2013.12020.x.
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• Califf, Robert M. “Better late than never: a welcome publication of tardy clinical trial results.” Jacc Heart Fail 1, no. 2 (April 2013): 112–14. https://doi.org/10.1016/j.jchf.2013.02.001.
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• Mentz, Robert J., Adrian F. Hernandez, Amanda Stebbins, Justin A. Ezekowitz, G Michael Felker, Gretchen M. Heizer, Dan Atar, et al. “Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF.” Eur J Heart Fail 15, no. 4 (April 2013): 456–64. https://doi.org/10.1093/eurjhf/hfs188.
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• Califf, Robert M. “Conflicting information about conflict of interest.” J Am Coll Cardiol 61, no. 11 (March 19, 2013): 1144–45. https://doi.org/10.1016/j.jacc.2012.12.030.
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• Califf, Robert M. “Attribution of causality in clinical research: an important element for learning health systems.” Am Heart J 165, no. 3 (March 2013): 252–53. https://doi.org/10.1016/j.ahj.2013.01.014.
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• Westerhout, Cynthia M., Karen S. Pieper, Stefan K. James, Kenneth W. Mahaffey, Frans Van de Werf, Robert M. Califf, Christopher B. Granger, and Paul W. Armstrong. “Dynamic modeling of 90-day mortality in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention.” Am Heart J 165, no. 3 (March 2013): 354-62.e2. https://doi.org/10.1016/j.ahj.2012.12.001.
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• Wong, Yee Weng, Laine Thomas, Jie-Lena Sun, John J. V. McMurray, Henry Krum, Adrian F. Hernandez, Guy E. H. M. Rutten, et al. “Predictors of incident heart failure hospitalizations among patients with impaired glucose tolerance: insight from the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research study.” Circ Heart Fail 6, no. 2 (March 2013): 203–10. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000086.
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• Singer, Daniel E., Anne S. Hellkamp, Jonathan P. Piccini, Kenneth W. Mahaffey, Yuliya Lokhnygina, Guohua Pan, Jonathan L. Halperin, et al. “Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial.” J Am Heart Assoc 2, no. 1 (February 19, 2013): e000067. https://doi.org/10.1161/JAHA.112.000067.
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• Patel, Manesh R., Anne S. Hellkamp, Yuliya Lokhnygina, Jonathan P. Piccini, Zhongxin Zhang, Surya Mohanty, Daniel E. Singer, et al. “Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation).” J Am Coll Cardiol 61, no. 6 (February 12, 2013): 651–58. https://doi.org/10.1016/j.jacc.2012.09.057.
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• Plapp, Bryce V., Natalia Y. Kedishvili, Tea Lanišnik Rižner, Edmund Maser, and Peter J. O’Brien. “Chemico-Biological Interactions. Enzymology and molecular biology of carbonyl metabolism 16. Introduction.” Chemico Biological Interactions 202, no. 1–3 (February 2013): 1. https://doi.org/10.1016/j.cbi.2013.02.004.
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• Piccini, Jonathan P., Susanna R. Stevens, YuChiao Chang, Daniel E. Singer, Yuliya Lokhnygina, Alan S. Go, Manesh R. Patel, et al. “Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts.” Circulation 127, no. 2 (January 15, 2013): 224–32. https://doi.org/10.1161/CIRCULATIONAHA.112.107128.
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• Abbott, D., R. Califf, B. W. Morrison, C. Pierre, J. Bolte, and S. Chakraborty. “Cycle Time Metrics for Multisite Clinical Trials in the United States.” Drug Information Journal 47, no. 2 (2013): 152–60. https://doi.org/10.1177/2168479012464371.
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• Califf, R. M. “Conflicting Information About Conflict of Interest.” Journal of the American College of Cardiology, 2013.
• Califf, Robert M. “Biomarkers, putative surrogates, surrogates, and decision making.” Circ Cardiovasc Imaging 6, no. 1 (January 1, 2013): 6–7. https://doi.org/10.1161/CIRCIMAGING.112.982538.
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• Granger, Bradi B., Shelley A. Rusincovitch, Suzanne Avery, Bryan C. Batch, Ashley A. Dunham, Mark N. Feinglos, Katherine Kelly, Marjorie Pierre-Louis, Susan E. Spratt, and Robert M. Califf. “Missing signposts on the roadmap to quality: a call to improve medication adherence indicators in data collection for population research.” Front Pharmacol 4 (2013): 139. https://doi.org/10.3389/fphar.2013.00139.
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• McCullough, Peter A., Huiman X. Barnhart, Jula K. Inrig, Donal Reddan, Shelly Sapp, Uptal D. Patel, Ajay K. Singh, Lynda A. Szczech, and Robert M. Califf. “Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease.” Am J Nephrol 37, no. 6 (2013): 549–58. https://doi.org/10.1159/000351175.
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• Leonardi, Sergio, Laine Thomas, Megan L. Neely, Pierluigi Tricoci, Renato D. Lopes, Harvey D. White, Paul W. Armstrong, et al. “Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction.” J Am Coll Cardiol 60, no. 22 (December 4, 2012): 2296–2304. https://doi.org/10.1016/j.jacc.2012.09.005.
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• Califf, Robert M., Iain Sanderson, and Marie Lynn Miranda. “The future of cardiovascular clinical research: informatics, clinical investigators, and community engagement.” Jama 308, no. 17 (November 7, 2012): 1747–48. https://doi.org/10.1001/jama.2012.28745.
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• Eisenstein, Eric L., Daniel Wojdyla, Kevin J. Anstrom, J Matthew Brennan, Robert M. Califf, Eric D. Peterson, and Pamela S. Douglas. “Evaluating the impact of public health notification: Duke clopidogrel experience.” Circ Cardiovasc Qual Outcomes 5, no. 6 (November 2012): 767–74. https://doi.org/10.1161/CIRCOUTCOMES.111.963330.
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• Felker, G Michael, Vic Hasselblad, WH Wilson Tang, Adrian F. Hernandez, Paul W. Armstrong, Gregg C. Fonarow, Adriaan A. Voors, et al. “Troponin I in acute decompensated heart failure: insights from the ASCEND-HF study.” Eur J Heart Fail 14, no. 11 (November 2012): 1257–64. https://doi.org/10.1093/eurjhf/hfs110.
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• Duval, Sue, Joseph M. Massaro, Michael R. Jaff, William E. Boden, Mark J. Alberts, Robert M. Califf, Kim A. Eagle, et al. “An evidence-based score to detect prevalent peripheral artery disease (PAD).” Vasc Med 17, no. 5 (October 2012): 342–51. https://doi.org/10.1177/1358863X12445102.
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• McMurray, John J. V., Robert M. Califf, Angelyn M. Bethel, Steven M. Haffner, and Rury R. Holman. “Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for hypertension on clinical end points: a cohort study.” J Clin Hypertens (Greenwich) 14, no. 10 (October 2012): 731. https://doi.org/10.1111/j.1751-7176.2012.00687.x.
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• McMurray, John J. V., Steven M. Haffner, Robert M. Califf, and Rury R. Holman. “Prediabetes and the risk of diabetes.” Lancet (London, England) 380, no. 9849 (October 2012): 1225–26. https://doi.org/10.1016/s0140-6736(12)61706-1.
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• Fuster, Valentin, Deepak L. Bhatt, Robert M. Califf, Alan D. Michelson, Marc S. Sabatine, Dominick J. Angiolillo, Eric R. Bates, et al. “Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group.” Circulation 126, no. 13 (September 25, 2012): 1645–62. https://doi.org/10.1161/CIRCULATIONAHA.112.105908.
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• Antman, E. M., R. M. Califf, and N. K. Choudhry. “Tools for assessment of cardiovascular tests and therapies,” September 1, 2012, 1–32. https://doi.org/10.1016/B978-1-4557-0101-8.00001-1.
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• Inrig, Jula K., Huiman X. Barnhart, Donal Reddan, Uptal D. Patel, Shelly Sapp, Robert M. Califf, Ajay K. Singh, and Lynda A. Szczech. “Effect of hemoglobin target on progression of kidney disease: a secondary analysis of the CHOIR (Correction of Hemoglobin and Outcomes in Renal Insufficiency) trial.” American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 60, no. 3 (September 2012): 390–401. https://doi.org/10.1053/j.ajkd.2012.03.009.
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• Inrig, Jula K., Shelly Sapp, Huiman Barnhart, Uptal D. Patel, Donal Reddan, Ajay Singh, Robert M. Califf, and Lynda Szczech. “Impact of higher hemoglobin targets on blood pressure and clinical outcomes: a secondary analysis of CHOIR.” Nephrol Dial Transplant 27, no. 9 (September 2012): 3606–14. https://doi.org/10.1093/ndt/gfs123.
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• Lopes, Renato D., Judson B. Williams, Rajendra H. Mehta, Eric M. Reyes, Gail E. Hafley, Keith B. Allen, Michael J. Mack, et al. “Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results.” Am Heart J 164, no. 3 (September 2012): 379-386.e1. https://doi.org/10.1016/j.ahj.2012.05.019.
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• Pride, Yuri B., Satishkumar Mohanavelu, Cafer Zorkun, Vijayalakshmi Kunadian, Robert P. Giugliano, L Kristin Newby, Eugene Braunwald, et al. “Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) angiographic substudy.” Jacc Cardiovasc Interv 5, no. 9 (September 2012): 927–35. https://doi.org/10.1016/j.jcin.2012.05.007.
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• Califf, Robert M. “In search of the efficient way to medical decisions: the case of acute heart failure syndrome.” Am Heart J 164, no. 2 (August 2012): 135–37. https://doi.org/10.1016/j.ahj.2012.05.006.
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• Califf, Robert M. “The trouble with ischemia.” Am Heart J 164, no. 2 (August 2012): 133–34. https://doi.org/10.1016/j.ahj.2012.06.007.
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• Piccini, Jonathan P., Jennifer A. White, Rajendra H. Mehta, Yuliya Lokhnygina, Sana M. Al-Khatib, Pierluigi Tricoci, Charles V. Pollack, et al. “Sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes.” Circulation 126, no. 1 (July 3, 2012): 41–49. https://doi.org/10.1161/CIRCULATIONAHA.111.071860.
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• Adams, Julie, Maragatha Kuchibhatla, Eric J. Christopher, Jude D. Alexander, Greg L. Clary, Michael S. Cuffe, Robert M. Califf, Ranga R. Krishnan, Christopher M. O’Connor, and Wei Jiang. “Association of depression and survival in patients with chronic heart failure over 12 Years.” Psychosomatics 53, no. 4 (July 2012): 339–46. https://doi.org/10.1016/j.psym.2011.12.002.
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• Thomas, Michael P., Kenneth W. Mahaffey, Karen Chiswell, Marc Cohen, Michael C. Kontos, Elliott M. Antman, James J. Ferguson, Robert M. Califf, Shaun G. Goodman, and Richard C. Becker. “Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin.” J Thromb Thrombolysis 34, no. 1 (July 2012): 114–19. https://doi.org/10.1007/s11239-012-0693-y.
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• Califf, Robert M., and Sally Kornbluth. “Establishing a framework for improving the quality of clinical and translational research.” J Clin Oncol 30, no. 14 (May 10, 2012): 1725–26. https://doi.org/10.1200/JCO.2011.41.4458.
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• Califf, Robert M. “A new look at an old therapy.” Jama 307, no. 18 (May 9, 2012): 1972–73. https://doi.org/10.1001/jama.2012.4434.
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• Califf, Robert M., Deborah A. Zarin, Judith M. Kramer, Rachel E. Sherman, Laura H. Aberle, and Asba Tasneem. “Characteristics of clinical trials registered in ClinicalTrials.gov, 2007-2010.” Jama 307, no. 17 (May 2, 2012): 1838–47. https://doi.org/10.1001/jama.2012.3424.
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• Meris, Alessandra, Maria Amigoni, Anil Verma, Jens Jakob Thune, Lars Køber, Eric Velazquez, John J. V. McMurray, et al. “Mechanisms and predictors of mitral regurgitation after high-risk myocardial infarction.” J Am Soc Echocardiogr 25, no. 5 (May 2012): 535–42. https://doi.org/10.1016/j.echo.2012.01.006.
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• Shah, Svati H., Jie-Lena Sun, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, Karen S. Pieper, Carol Haynes, et al. “Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease.” Am Heart J 163, no. 5 (May 2012): 844-850.e1. https://doi.org/10.1016/j.ahj.2012.02.005.
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• Ezekowitz, Justin A., Adrian F. Hernandez, Christopher M. O’Connor, Randall C. Starling, Guy Proulx, Mason H. Weiss, Jeffrey A. Bakal, Robert M. Califf, John J. V. McMurray, and Paul W. Armstrong. “Assessment of dyspnea in acute decompensated heart failure: insights from ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure) on the contributions of peak expiratory flow.” J Am Coll Cardiol 59, no. 16 (April 17, 2012): 1441–48. https://doi.org/10.1016/j.jacc.2011.11.061.
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• Hankey, Graeme J., Manesh R. Patel, Susanna R. Stevens, Richard C. Becker, Günter Breithardt, Antonio Carolei, Hans-Christoph Diener, et al. “Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF.” Lancet Neurol 11, no. 4 (April 2012): 315–22. https://doi.org/10.1016/S1474-4422(12)70042-X.
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• Granger, Bradi B., Janet Prvu-Bettger, Julia Aucoin, Mary Ann Fuchs, Pamela H. Mitchell, Diane Holditch-Davis, Deborah Roth, Robert M. Califf, and Catherine L. Gilliss. “An academic-health service partnership in nursing: lessons from the field.” J Nurs Scholarsh 44, no. 1 (March 2012): 71–79. https://doi.org/10.1111/j.1547-5069.2011.01432.x.
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• Kramer, J. M., P. B. Smith, and R. M. Califf. “Impediments to clinical research in the United States.” Clinical Pharmacology and Therapeutics 91, no. 3 (March 2012): 535–41. https://doi.org/10.1038/clpt.2011.341.
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• Roe, Matthew T., Jennifer A. White, Padma Kaul, Pierluigi Tricoci, Yuliya Lokhnygina, Chadwick D. Miller, Arnoud W. van’t Hof, et al. “Regional patterns of use of a medical management strategy for patients with non-ST-segment elevation acute coronary syndromes: insights from the EARLY ACS Trial.” Circ Cardiovasc Qual Outcomes 5, no. 2 (March 1, 2012): 205–13. https://doi.org/10.1161/CIRCOUTCOMES.111.962332.
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• Lopes, Renato D., Rajendra H. Mehta, Gail E. Hafley, Judson B. Williams, Michael J. Mack, Eric D. Peterson, Keith B. Allen, et al. “Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery.” Circulation 125, no. 6 (February 14, 2012): 749–56. https://doi.org/10.1161/CIRCULATIONAHA.111.040311.
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• Mehta, Rajendra H., Amanda S. Stebbins, Renato D. Lopes, Robert M. Califf, Karen S. Pieper, Paul W. Armstrong, Frans Van de Werf, et al. “Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis.” Am J Cardiol 109, no. 3 (February 1, 2012): 320–26. https://doi.org/10.1016/j.amjcard.2011.09.012.
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• Bhattacharya, Sayanti, Ashley A. Dunham, Melissa A. Cornish, Victoria A. Christian, Geoffrey S. Ginsburg, Jessica D. Tenenbaum, Meredith L. Nahm, et al. “The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study Community Registry and Biorepository.” Am J Transl Res 4, no. 4 (2012): 458–70.
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• Preiss, David, Laine E. Thomas, Jie-Lena Sun, Steven M. Haffner, Rury R. Holman, Eberhard Standl, Lawrence A. Leiter, et al. “Predictors of cardiovascular events in a contemporary population with impaired glucose tolerance: an observational analysis of the Nateglinide and Valsartan in impaired glucose tolerance outcomes research (NAVIGATOR) trial.” Bmj Open 2, no. 6 (2012). https://doi.org/10.1136/bmjopen-2012-001925.
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• Tenenbaum, Jessica D., Victoria Christian, Melissa A. Cornish, Rowena J. Dolor, Ashley A. Dunham, Geoffrey S. Ginsburg, Virginia B. Kraus, et al. “The MURDOCK Study: a long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records.” Am J Transl Res 4, no. 3 (2012): 291–301.
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• Califf, Robert M. “Commentary on Anand et al.” Clin Trials 8, no. 6 (December 2011): 724–25. https://doi.org/10.1177/1740774511427169.
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• Melloni, Chiara, Stefan K. James, Jennifer A. White, Robert P. Giugliano, Robert A. Harrington, Kurt Huber, Pierluigi Tricoci, et al. “Safety and efficacy of adjusted-dose eptifibatide in patients with acute coronary syndromes and reduced renal function.” Am Heart J 162, no. 5 (November 2011): 884-892.e1. https://doi.org/10.1016/j.ahj.2011.08.020.
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• Kramer, Daniel B. “Nesiritide in acute decompensated heart failure.” N Engl J Med 365, no. 16 (October 20, 2011): 1547. https://doi.org/10.1056/NEJMc1109292.
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• Fiuzat, Mona, and Robert M. Califf. “Conduct of clinical trials in acute heart failure: regional differences in heart failure clinical trials.” Heart Fail Clin 7, no. 4 (October 2011): 539–44. https://doi.org/10.1016/j.hfc.2011.06.004.
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• Fox, Keith A. A., Jonathan P. Piccini, Daniel Wojdyla, Richard C. Becker, Jonathan L. Halperin, Christopher C. Nessel, John F. Paolini, et al. “Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment.” Eur Heart J 32, no. 19 (October 2011): 2387–94. https://doi.org/10.1093/eurheartj/ehr342.
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• Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Judson B. Williams, Linda K. Shaw, Sean M. O’Brien, Robert M. Califf, G Chad Hughes, and Michael H. Sketch. “Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury.” Circulation 124, no. 11 Suppl (September 13, 2011): S149–55. https://doi.org/10.1161/CIRCULATIONAHA.110.011700.
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• Patel, Manesh R., Kenneth W. Mahaffey, Jyotsna Garg, Guohua Pan, Daniel E. Singer, Werner Hacke, Günter Breithardt, et al. “Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.” N Engl J Med 365, no. 10 (September 8, 2011): 883–91. https://doi.org/10.1056/NEJMoa1009638.
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• Califf, Robert M., and Robert A. Harrington. “American industry and the U.S. Cardiovascular Clinical Research Enterprise an appropriate analogy?” J Am Coll Cardiol 58, no. 7 (August 9, 2011): 677–80. https://doi.org/10.1016/j.jacc.2011.03.048.
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• Lopes, Renato D., Richard C. Becker, John H. Alexander, Paul W. Armstrong, Robert M. Califf, Mark Y. Chan, Mark Crowther, et al. “Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil.” J Thromb Thrombolysis 32, no. 2 (August 2011): 242–66. https://doi.org/10.1007/s11239-011-0592-7.
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• Shah, Monica R., Robert M. Califf, Anju Nohria, Manju Bhapkar, Margaret Bowers, Donna M. Mancini, Mona Fiuzat, Lynne W. Stevenson, and Christopher M. O’Connor. “The STARBRITE trial: a randomized, pilot study of B-type natriuretic peptide-guided therapy in patients with advanced heart failure.” J Card Fail 17, no. 8 (August 2011): 613–21. https://doi.org/10.1016/j.cardfail.2011.04.012.
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• Mehta, Rajendra H., T Bruce Ferguson, Renato D. Lopes, Gail E. Hafley, Michael J. Mack, Nicholas T. Kouchoukos, C Michael Gibson, et al. “Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV trial.” Circulation 124, no. 3 (July 19, 2011): 280–88. https://doi.org/10.1161/CIRCULATIONAHA.110.991299.
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• O’Connor, C. M., R. C. Starling, A. F. Hernandez, P. W. Armstrong, K. Dickstein, V. Hasselblad, G. M. Heizer, et al. “Effect of nesiritide in patients with acute decompensated heart failure.” N Engl J Med 365, no. 1 (July 7, 2011): 32–43. https://doi.org/10.1056/NEJMoa1100171.
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• Tricoci, Pierluigi, L Kristin Newby, Vic Hasselblad, David F. Kong, Robert P. Giugliano, Harvey D. White, Pierre Théroux, et al. “Upstream use of small-molecule glycoprotein iib/iiia inhibitors in patients with non-ST-segment elevation acute coronary syndromes: a systematic overview of randomized clinical trials.” Circ Cardiovasc Qual Outcomes 4, no. 4 (July 2011): 448–58. https://doi.org/10.1161/CIRCOUTCOMES.110.960294.
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• Ye, Siqin, Matthew Grunnert, Jens Jakob Thune, Kent M. Stephenson, Hajime Uno, Peter V. Finn, John J. V. McMurray, et al. “Circumstances and outcomes of sudden unexpected death in patients with high-risk myocardial infarction: implications for prevention.” Circulation 123, no. 23 (June 14, 2011): 2674–80. https://doi.org/10.1161/CIRCULATIONAHA.110.990655.
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• Patel, Keyur, Joseph E. Lucas, J Will Thompson, Laura G. Dubois, Hans L. Tillmann, Alexander J. Thompson, Diane Uzarski, et al. “High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients.” Hepatology 53, no. 6 (June 2011): 1809–18. https://doi.org/10.1002/hep.24284.
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• Verma, Anil, Marc A. Pfeffer, Hicham Skali, Jean Rouleau, Aldo Maggioni, John J. V. McMurray, Robert M. Califf, Eric J. Velazquez, and Scott D. Solomon. “Incremental value of echocardiographic assessment beyond clinical evaluation for prediction of death and development of heart failure after high-risk myocardial infarction.” Am Heart J 161, no. 6 (June 2011): 1156–62. https://doi.org/10.1016/j.ahj.2011.03.024.
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• Goyal, A., D. L. Bhatt, P. G. Steg, B. J. Gersh, M. J. Alberts, E. M. Ohman, R. M. Califf, et al. “Response to letter regarding article, "attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countries".” Circulation 123, no. 20 (May 24, 2011). https://doi.org/10.1161/CIRCULATIONAHA.111.025189.
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• Anderson, Jeffrey L., Cynthia D. Adams, Elliott M. Antman, Charles R. Bridges, Robert M. Califf, Donald E. Casey, William E. Chavey, et al. “2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.” Circulation 123, no. 18 (May 10, 2011): e426–579. https://doi.org/10.1161/CIR.0b013e318212bb8b.
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• Pouleur, A. C., E. Barkoudah, H. Uno, H. Skali, P. V. Finn, S. L. Zelenkofske, Y. N. Belenkov, et al. “Response to letter regarding article, "pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both".” Circulation 123, no. 18 (May 10, 2011). https://doi.org/10.1161/CIRCULATIONAHA.111.021600.
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• Wright, R Scott, Jeffrey L. Anderson, Cynthia D. Adams, Charles R. Bridges, Donald E. Casey, Steven M. Ettinger, Francis M. Fesmire, et al. “2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the American Academy of Family Physicians, Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons.” J Am Coll Cardiol 57, no. 19 (May 10, 2011): e215–367. https://doi.org/10.1016/j.jacc.2011.02.011.
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• Armstrong, Paul W., Cynthia M. Westerhout, Frans Van de Werf, Robert M. Califf, Robert C. Welsh, Robert G. Wilcox, and Jeffrey A. Bakal. “Refining clinical trial composite outcomes: an application to the Assessment of the Safety and Efficacy of a New Thrombolytic-3 (ASSENT-3) trial.” Am Heart J 161, no. 5 (May 2011): 848–54. https://doi.org/10.1016/j.ahj.2010.12.026.
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• Selker, Harry P., and Robert M. Califf. “The need for academic leadership in full-spectrum translational research.” Clin Transl Sci 4, no. 2 (April 2011): 78–79. https://doi.org/10.1111/j.1752-8062.2011.00275.x.
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• Zarin, Deborah A., Tony Tse, Rebecca J. Williams, Robert M. Califf, and Nicholas C. Ide. “The ClinicalTrials.gov results database--update and key issues.” N Engl J Med 364, no. 9 (March 3, 2011): 852–60. https://doi.org/10.1056/NEJMsa1012065.
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• Mahaffey, Kenneth W., Karen S. Pieper, Yuliya Lokhnygina, Robert M. Califf, Elliott M. Antman, Neal S. Kleiman, Shaun G. Goodman, et al. “The impact of postrandomization crossover of therapy in acute coronary syndromes care.” Circ Cardiovasc Qual Outcomes 4, no. 2 (March 2011): 211–19. https://doi.org/10.1161/CIRCOUTCOMES.109.853598.
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• Vamadevan, Ajay S., Bimal R. Shah, Robert M. Califf, and Dorairaj Prabhakaran. “Cardiovascular research in India: a perspective.” Am Heart J 161, no. 3 (March 2011): 431–38. https://doi.org/10.1016/j.ahj.2010.10.042.
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• Wang, Tracy Y., Jennifer A. White, Pierluigi Tricoci, Robert P. Giugliano, Uwe Zeymer, Robert A. Harrington, Gilles Montalescot, et al. “Upstream clopidogrel use and the efficacy and safety of early eptifibatide treatment in patients with acute coronary syndrome: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) trial.” Circulation 123, no. 7 (February 22, 2011): 722–30. https://doi.org/10.1161/CIRCULATIONAHA.110.958041.
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• DeMets, David L., and Robert M. Califf. “A historical perspective on clinical trials innovation and leadership: where have the academics gone?” Jama 305, no. 7 (February 16, 2011): 713–14. https://doi.org/10.1001/jama.2011.175.
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• Thune, Jens Jakob, James E. Signorovitch, Lars Kober, John J. V. McMurray, Karl Swedberg, Jean Rouleau, Aldo Maggioni, et al. “Predictors and prognostic impact of recurrent myocardial infarction in patients with left ventricular dysfunction, heart failure, or both following a first myocardial infarction.” Eur J Heart Fail 13, no. 2 (February 2011): 148–53. https://doi.org/10.1093/eurjhf/hfq194.
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• Mehta, Rajendra H., J Conor O’Shea, Amanda L. Stebbins, Christopher B. Granger, Paul W. Armstrong, Harvey D. White, Eric J. Topol, Robert M. Califf, and E Magnus Ohman. “Association of mortality with years of education in patients with ST-segment elevation myocardial infarction treated with fibrinolysis.” J Am Coll Cardiol 57, no. 2 (January 11, 2011): 138–46. https://doi.org/10.1016/j.jacc.2010.09.021.
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• Alexander, W., K. W. Mahaffey, E. M. Hylek, and R. M. Califf. “American Heart Association 2010 Scientific Sessions and American Society of Nephrology: Renal Week 2010. 43rd Annual Meeting & Scientific Exposition. Preventing stroke with Rivaroxaban (Xarelto) - The ROCKET-AF trial.” P and T 36, no. 1 (January 1, 2011).
• Mehta, Rajendra H., Amanda Stebbins, Renato D. Lopes, Sunil V. Rao, Eric R. Bates, Karen S. Pieper, Paul W. Armstrong, et al. “Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy.” Am J Med 124, no. 1 (January 2011): 48–57. https://doi.org/10.1016/j.amjmed.2010.07.028.
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• Piccini, Jonathan P., Phillip J. Schulte, Karen S. Pieper, Rajendra H. Mehta, Harvey D. White, Frans Van de Werf, Diego Ardissino, et al. “Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction.” Crit Care Med 39, no. 1 (January 2011): 78–83. https://doi.org/10.1097/CCM.0b013e3181fd6ad7.
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• Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Linda K. Shaw, Donald D. Glower, Robert A. Harrington, Robert M. Califf, and Michael H. Sketch. “Impact of recovery of renal function on long-term mortality after coronary artery bypass grafting.” Am J Cardiol 106, no. 12 (December 15, 2010): 1728–34. https://doi.org/10.1016/j.amjcard.2010.07.045.
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• Shah, Amil M., Hajime Uno, Lars Køber, Eric J. Velazquez, Aldo P. Maggioni, Michael R. MacDonald, Mark C. Petrie, et al. “The inter-relationship of diabetes and left ventricular systolic function on outcome after high-risk myocardial infarction.” Eur J Heart Fail 12, no. 11 (November 2010): 1229–37. https://doi.org/10.1093/eurjhf/hfq179.
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• Tackett, Andrea H., Alison L. Bailey, Joanne Micale Foody, Julie M. Miller, Carolyn Apperson-Hansen, E Magnus Ohman, Judith S. Hochman, et al. “Hormone replacement therapy among postmenopausal women presenting with acute myocardial infarction: insights from the GUSTO-III trial.” Am Heart J 160, no. 4 (October 2010): 678–84. https://doi.org/10.1016/j.ahj.2010.06.030.
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• Taekman, J. M., M. Stafford-Smith, E. J. Velazquez, M. C. Wright, B. G. Phillips-Bute, M. A. Pfeffer, M. A. Sellers, et al. “Departures from the protocol during conduct of a clinical trial: a pattern from the data record consistent with a learning curve.” Qual Saf Health Care 19, no. 5 (October 2010): 405–10. https://doi.org/10.1136/qshc.2008.028605.
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• Spinler, Sarah A., Kenneth W. Mahaffey, Dianne Gallup, Glenn N. Levine, James J. Ferguson, Sunil V. Rao, Richard Gallo, et al. “Relationship between renal function and outcomes in high-risk patients with non-ST-segment elevation acute coronary syndromes: results from SYNERGY.” Int J Cardiol 144, no. 1 (September 24, 2010): 36–41. https://doi.org/10.1016/j.ijcard.2009.03.119.
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• Goyal, Abhinav, Deepak L. Bhatt, P Gabriel Steg, Bernard J. Gersh, Mark J. Alberts, E Magnus Ohman, Ramón Corbalán, et al. “Attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countries.” Circulation 122, no. 12 (September 21, 2010): 1167–75. https://doi.org/10.1161/CIRCULATIONAHA.109.919274.
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• Boden, William E., Gregory S. Cherr, Kim A. Eagle, Christopher P. Cannon, Robert M. Califf, Alan T. Hirsch, Mark J. Alberts, et al. “Prior cardiovascular interventions are not associated with worsened clinical outcomes in patients with symptomatic atherothrombosis.” Crit Pathw Cardiol 9, no. 3 (September 2010): 116–25. https://doi.org/10.1097/HPC.0b013e3181e7f93e.
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• Shah, Svati H., Christopher B. Granger, Elizabeth R. Hauser, William E. Kraus, Jie-Lena Sun, Karen Pieper, Charlotte L. Nelson, et al. “Reclassification of cardiovascular risk using integrated clinical and molecular biosignatures: Design of and rationale for the Measurement to Understand the Reclassification of Disease of Cabarrus and Kannapolis (MURDOCK) Horizon 1 Cardiovascular Disease Study.” Am Heart J 160, no. 3 (September 2010): 371-379.e2. https://doi.org/10.1016/j.ahj.2010.06.051.
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• Pouleur, Anne-Catherine, Ebrahim Barkoudah, Hajime Uno, Hicham Skali, Peter V. Finn, Steven L. Zelenkofske, Yuri N. Belenkov, et al. “Pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both.” Circulation 122, no. 6 (August 10, 2010): 597–602. https://doi.org/10.1161/CIRCULATIONAHA.110.940619.
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• West, Ryenn L., Adrian F. Hernandez, Christopher M. O’Connor, Randall C. Starling, and Robert M. Califf. “A review of dyspnea in acute heart failure syndromes.” Am Heart J 160, no. 2 (August 2010): 209–14. https://doi.org/10.1016/j.ahj.2010.05.020.
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• Kong, Melissa H., Linda K. Shaw, Christopher O’Connor, Robert M. Califf, Michael A. Blazing, and Sana M. Al-Khatib. “Is rhythm-control superior to rate-control in patients with atrial fibrillation and diastolic heart failure?” Ann Noninvasive Electrocardiol 15, no. 3 (July 2010): 209–17. https://doi.org/10.1111/j.1542-474X.2010.00365.x.
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• Shamshad, Faisal, Satish Kenchaiah, Peter V. Finn, Jordi Soler-Soler, John J. V. McMurray, Eric J. Velazquez, Aldo P. Maggioni, et al. “Fatal myocardial rupture after acute myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALsartan In Acute myocardial iNfarcTion Trial (VALIANT).” Am Heart J 160, no. 1 (July 2010): 145–51. https://doi.org/10.1016/j.ahj.2010.02.037.
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• Baker-Smith, C. M., D. K. Benjamin, R. M. Califf, M. D. Murphy, J. S. Li, and P. B. Smith. “Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials.” Clinical Pharmacology and Therapeutics 87, no. 6 (June 2010): 668–71. https://doi.org/10.1038/clpt.2009.231.
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• Nilsson, Kent R., Sana M. Al-Khatib, Yi Zhou, Karen Pieper, Harvey D. White, Aldo P. Maggioni, Lars Kober, et al. “Atrial fibrillation management strategies and early mortality after myocardial infarction: results from the Valsartan in Acute Myocardial Infarction (VALIANT) Trial.” Heart 96, no. 11 (June 2010): 838–42. https://doi.org/10.1136/hrt.2009.180182.
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• Simes, R John, Rachel L. O’Connell, Philip E. Aylward, Sergei Varshavsky, Rafael Diaz, Robert G. Wilcox, Paul W. Armstrong, et al. “Unexplained international differences in clinical outcomes after acute myocardial infarction and fibrinolytic therapy: lessons from the Hirulog and Early Reperfusion or Occlusion (HERO)-2 trial.” Am Heart J 159, no. 6 (June 2010): 988–97. https://doi.org/10.1016/j.ahj.2009.12.044.
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• Harrington, R. A., and R. M. Califf. “Response to avorn and choudhry.” Circulation 121, no. 20 (May 25, 2010): 2234. https://doi.org/10.1161/CIRCULATIONAHA.109.869636.
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• Harrington, Robert A., and Robert M. Califf. “There is a role for industry-sponsored education in cardiology.” Circulation 121, no. 20 (May 25, 2010): 2221–27. https://doi.org/10.1161/CIRCULATIONAHA.109.868026.
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• Califf, Robert M., Yuliya Lokhnygina, Christopher P. Cannon, Michael E. Stepanavage, Carolyn H. McCabe, Thomas A. Musliner, Richard C. Pasternak, et al. “An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design.” Am Heart J 159, no. 5 (May 2010): 705–9. https://doi.org/10.1016/j.ahj.2010.03.004.
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• Cohen, Marc, Glenn N. Levine, Karen S. Pieper, Lan Lan, Elliott M. Antman, Philip E. Aylward, Harvey D. White, et al. “Enoxaparin 0.3 mg/kg IV supplement for patients transitioning to PCI after subcutaneous enoxaparin therapy for NSTE ACS: a subgroup analysis from the SYNERGY trial.” Catheter Cardiovasc Interv 75, no. 6 (May 1, 2010): 928–35. https://doi.org/10.1002/ccd.22340.
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• Eggers, Kai M., Paul W. Armstrong, Robert M. Califf, Maarten L. Simoons, Per Venge, Lars Wallentin, and Stefan K. James. “ST2 and mortality in non-ST-segment elevation acute coronary syndrome.” Am Heart J 159, no. 5 (May 2010): 788–94. https://doi.org/10.1016/j.ahj.2010.02.022.
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• Rao, Sunil V., and Robert M. Califf. “Is old blood bad blood?” Am Heart J 159, no. 5 (May 2010): 710–12. https://doi.org/10.1016/j.ahj.2010.02.017.
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• NAVIGATOR Study Group, Robert M., John J. McMurray, Rury R. Holman, Steven M. Haffner, M Angelyn Bethel, Björn Holzhauer, Tsushung A. Hua, et al. “Effect of valsartan on the incidence of diabetes and cardiovascular events.” N Engl J Med 362, no. 16 (April 22, 2010): 1477–90. https://doi.org/10.1056/NEJMoa1001121.
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• NAVIGATOR Study Group, Robert M., Rury R. Holman, Steven M. Haffner, John J. McMurray, M Angelyn Bethel, Björn Holzhauer, Tsushung A. Hua, et al. “Effect of nateglinide on the incidence of diabetes and cardiovascular events.” N Engl J Med 362, no. 16 (April 22, 2010): 1463–76. https://doi.org/10.1056/NEJMoa1001122.
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• Califf, Robert M., Paul W. Armstrong, Christopher B. Granger, Robert A. Harrington, Kerry Lee, R John Simes, Frans Van de Werf, Lars Wallentin, Harvey D. White, and Harvey D. Virtual Coordinating Centre for Global Collaborative Cardiovascular Research Organization. “Towards a new order in cardiovascular medicine: re-engineering through global collaboration.” Eur Heart J 31, no. 8 (April 2010): 911–17. https://doi.org/10.1093/eurheartj/ehp550.
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• Krum, Henry, John J. V. McMurray, Edward Horton, Teresa Gerlock, Bjoern Holzhauer, Lineke Zuurman, Steven M. Haffner, M Angelyn Bethel, Rury R. Holman, and Robert M. Califf. “Baseline characteristics of the Nateglinide and Valsartan Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial population: comparison with other diabetes prevention trials.” Cardiovasc Ther 28, no. 2 (April 2010): 124–32. https://doi.org/10.1111/j.1755-5922.2010.00146.x.
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• Califf, Robert M., Svati H. Shah, and L Kristin Newby. “Biomarker bonanza?” J Am Coll Cardiol 55, no. 12 (March 23, 2010): 1197–99. https://doi.org/10.1016/j.jacc.2009.10.051.
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• Dzau, Victor J., D Clay Ackerly, Pamela Sutton-Wallace, Michael H. Merson, R Sanders Williams, K Ranga Krishnan, Robert C. Taber, and Robert M. Califf. “The role of academic health science systems in the transformation of medicine.” Lancet 375, no. 9718 (March 13, 2010): 949–53. https://doi.org/10.1016/S0140-6736(09)61082-5.
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• Shin, Sung-Hee, Chung-Lieh Hung, Hajime Uno, Amira H. Hassanein, Anil Verma, Mikhail Bourgoun, Lars Køber, et al. “Mechanical dyssynchrony after myocardial infarction in patients with left ventricular dysfunction, heart failure, or both.” Circulation 121, no. 9 (March 9, 2010): 1096–1103. https://doi.org/10.1161/CIRCULATIONAHA.109.863795.
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• Mahaffey, Kenneth W., Simon T. Tonev, Sarah A. Spinler, Glenn N. Levine, Richard Gallo, John Ducas, Shaun G. Goodman, et al. “Obesity in patients with non-ST-segment elevation acute coronary syndromes: results from the SYNERGY trial.” Int J Cardiol 139, no. 2 (March 4, 2010): 123–33. https://doi.org/10.1016/j.ijcard.2008.10.008.
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• O’Connor, Christopher M., Vic Hasselblad, Rajendra H. Mehta, Gudaye Tasissa, Robert M. Califf, Mona Fiuzat, Joseph G. Rogers, Carl V. Leier, and Lynne W. Stevenson. “Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score.” J Am Coll Cardiol 55, no. 9 (March 2, 2010): 872–78. https://doi.org/10.1016/j.jacc.2009.08.083.
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• Califf, Robert M., Lars Berglund, and Lars Principal Investigators of National Institutes of Health Clinical and Translational Science Awards. “Linking scientific discovery and better health for the nation: the first three years of the NIH's Clinical and Translational Science Awards.” Acad Med 85, no. 3 (March 2010): 457–62. https://doi.org/10.1097/ACM.0b013e3181ccb74d.
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• Petersen, John L., John J. Barron, Bradley G. Hammill, Mark J. Cziraky, Kevin J. Anstrom, Peter M. Wahl, Eric L. Eisenstein, et al. “Clopidogrel use and clinical events after drug-eluting stent implantation: findings from the HealthCore Integrated Research Database.” Am Heart J 159, no. 3 (March 2010): 462-470.e1. https://doi.org/10.1016/j.ahj.2009.11.031.
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• Reis, Steven E., Lars Berglund, Gordon R. Bernard, Robert M. Califf, Garret A. Fitzgerald, Peter C. Johnson, and Peter C. National Clinical and Translational Science Awards Consortium. “Reengineering the national clinical and translational research enterprise: the strategic plan of the National Clinical and Translational Science Awards Consortium.” Acad Med 85, no. 3 (March 2010): 463–69. https://doi.org/10.1097/ACM.0b013e3181ccc877.
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• Cannon, Christopher P., Karen E. Rhee, Robert M. Califf, William E. Boden, Alan T. Hirsch, Mark J. Alberts, Greg Cable, et al. “Current use of aspirin and antithrombotic agents in the United States among outpatients with atherothrombotic disease (from the REduction of Atherothrombosis for Continued Health [REACH] Registry).” Am J Cardiol 105, no. 4 (February 15, 2010): 445–52. https://doi.org/10.1016/j.amjcard.2009.10.014.
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• Ohman, E Magnus, and Robert M. Califf. “When can noninferior be superior? The multidimensional nature of clinical decision-making calls for innovative approaches to clinical trials.” J Am Coll Cardiol 55, no. 6 (February 9, 2010): 555–57. https://doi.org/10.1016/j.jacc.2009.10.027.
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• Katz, Jason N., Bimal R. Shah, Elizabeth M. Volz, John R. Horton, Linda K. Shaw, L Kristin Newby, Christopher B. Granger, Daniel B. Mark, Robert M. Califf, and Richard C. Becker. “Evolution of the coronary care unit: clinical characteristics and temporal trends in healthcare delivery and outcomes.” Crit Care Med 38, no. 2 (February 2010): 375–81. https://doi.org/10.1097/CCM.0b013e3181cb0a63.
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• Szczech, Lynda A., Huiman X. Barnhart, Shelly Sapp, G Michael Felker, Adrian Hernandez, Donal Reddan, Robert M. Califf, Jula K. Inrig, Uptal D. Patel, and Ajay K. Singh. “A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment.” Kidney International 77, no. 3 (February 2010): 239–46. https://doi.org/10.1038/ki.2009.415.
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• Piccini, Jonathan P., Min Zhang, Karen Pieper, Scott D. Solomon, Sana M. Al-Khatib, Frans Van de Werf, Marc A. Pfeffer, John J. V. McMurray, Robert M. Califf, and Eric J. Velazquez. “Predictors of sudden cardiac death change with time after myocardial infarction: results from the VALIANT trial.” Eur Heart J 31, no. 2 (January 2010): 211–21. https://doi.org/10.1093/eurheartj/ehp425.
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• Atwater, Brett D., Vivian P. Thompson, Richard N. Vest, Linda K. Shaw, Walter R. Mazzei, Sana M. Al-Khatib, Patrick M. Hranitzky, et al. “Usefulness of the Duke Sudden Cardiac Death risk score for predicting sudden cardiac death in patients with angiographic (>75% narrowing) coronary artery disease.” Am J Cardiol 104, no. 12 (December 15, 2009): 1624–30. https://doi.org/10.1016/j.amjcard.2009.07.042.
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• Coller, Barry S., and Robert M. Califf. “Traversing the valley of death: a guide to assessing prospects for translational success.” Sci Transl Med 1, no. 10 (December 9, 2009): 10cm9. https://doi.org/10.1126/scitranslmed.3000265.
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• Benjamin, Daniel K., P Brian Smith, M Jessica M. Sun, M Dianne Murphy, Debbie Avant, Lisa Mathis, William Rodriguez, Robert M. Califf, and Jennifer S. Li. “Safety and transparency of pediatric drug trials.” Arch Pediatr Adolesc Med 163, no. 12 (December 2009): 1080–86. https://doi.org/10.1001/archpediatrics.2009.229.
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• Bethel, M. A., P. Deedwania, N. S. Levitt, O. Schmitz, A. Huntsman-Labed, R. M. Califf, S. M. Haffner, P. Diem, and P. NAVIGATOR Study Group. “Metabolic syndrome and alanine aminotransferase: a global perspective from the NAVIGATOR screening population.” Diabet Med 26, no. 12 (December 2009): 1204–11. https://doi.org/10.1111/j.1464-5491.2009.02864.x.
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• Califf, R. M. “Clinical Trials,” December 1, 2009, 13–37. https://doi.org/10.1016/B978-0-12-373639-0.00002-9.
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• Goldschmidt-Clermont, Pascal J., Chunming Dong, Nancy M. Rhodes, Diana B. McNeill, Martha B. Adams, Catherine L. Gilliss, Michael S. Cuffe, Robert M. Califf, Eric D. Peterson, and David A. Lubarsky. “Perspective: Autonomic care systems for hospitalized patients.” Acad Med 84, no. 12 (December 2009): 1727–31. https://doi.org/10.1097/ACM.0b013e3181bf9bfd.
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• Meadows, Telly A., Deepak L. Bhatt, Alan T. Hirsch, Mark A. Creager, Robert M. Califf, E Magnus Ohman, Christopher P. Cannon, et al. “Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry.” Am Heart J 158, no. 6 (December 2009): 1038–45. https://doi.org/10.1016/j.ahj.2009.09.014.
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• Linefsky, Jason P., Min Lin, Karen S. Pieper, Craig J. Reist, Lisa G. Berdan, Elliott M. Antman, Shaun G. Goodman, et al. “Comparison of site-reported and core laboratory-reported creatine kinase-MB values in non-ST-segment elevation acute coronary syndrome (from the international trial SYNERGY).” Am J Cardiol 104, no. 10 (November 15, 2009): 1330–35. https://doi.org/10.1016/j.amjcard.2009.06.056.
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• Califf, Robert M. “Clinical research sites--the underappreciated component of the clinical research system.” Jama 302, no. 18 (November 11, 2009): 2025–27. https://doi.org/10.1001/jama.2009.1655.
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• Al-Khatib, Sana M., Gail Hafley, Robert A. Harrington, Michael J. Mack, Thomas Bruce Ferguson, Eric D. Peterson, Robert M. Califf, Nicholas T. Kouchoukos, and John H. Alexander. “Patterns of management of atrial fibrillation complicating coronary artery bypass grafting: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT-IV) Trial.” Am Heart J 158, no. 5 (November 2009): 792–98. https://doi.org/10.1016/j.ahj.2009.09.003.
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• Mielniczuk, Lisa M., Marc A. Pfeffer, Eldrin F. Lewis, Michael A. Blazing, James A. de Lemos, Satishkumar Mohanavelu, Jean Rouleau, Keith Fox, Terje R. Pedersen, and Robert M. Califf. “Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome.” Clin J Am Soc Nephrol 4, no. 11 (November 2009): 1811–17. https://doi.org/10.2215/CJN.03510509.
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• Piccini, Jonathan P., Vic Hasselblad, Eric D. Peterson, Jeffrey B. Washam, Robert M. Califf, and David F. Kong. “Comparative efficacy of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation.” J Am Coll Cardiol 54, no. 12 (September 15, 2009): 1089–95. https://doi.org/10.1016/j.jacc.2009.04.085.
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• Bonaca, Marc P., Philippe Gabriel Steg, Laurent J. Feldman, John F. Canales, James J. Ferguson, Lars Wallentin, Robert M. Califf, Robert A. Harrington, and Robert P. Giugliano. “Antithrombotics in acute coronary syndromes.” J Am Coll Cardiol 54, no. 11 (September 8, 2009): 969–84. https://doi.org/10.1016/j.jacc.2009.03.083.
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• Kumar, Amit, Gregg C. Fonarow, Kim A. Eagle, Alan T. Hirsch, Robert M. Califf, Mark J. Alberts, William E. Boden, et al. “Regional and practice variation in adherence to guideline recommendations for secondary and primary prevention among outpatients with atherothrombosis or risk factors in the United States: a report from the REACH Registry.” Crit Pathw Cardiol 8, no. 3 (September 2009): 104–11. https://doi.org/10.1097/HPC.0b013e3181b8395d.
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• Moukarbel, George V., James E. Signorovitch, Marc A. Pfeffer, John J. V. McMurray, Harvey D. White, Aldo P. Maggioni, Eric J. Velazquez, Robert M. Califf, James M. Scheiman, and Scott D. Solomon. “Gastrointestinal bleeding in high risk survivors of myocardial infarction: the VALIANT Trial.” Eur Heart J 30, no. 18 (September 2009): 2226–32. https://doi.org/10.1093/eurheartj/ehp256.
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• Berger, Jeffrey S., Laine Elliott, Dianne Gallup, Matthew Roe, Christopher B. Granger, Paul W. Armstrong, R John Simes, et al. “Sex differences in mortality following acute coronary syndromes.” Jama 302, no. 8 (August 26, 2009): 874–82. https://doi.org/10.1001/jama.2009.1227.
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• Califf, Robert M., Robert A. Harrington, and Michael A. Blazing. “Premature release of data from clinical trials of ezetimibe.” N Engl J Med 361, no. 7 (August 13, 2009): 712–17. https://doi.org/10.1056/NEJMsr0900910.
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• Califf, Robert M., and Robert M. Virtual Coordinating Centre for Global Collaborative Cardiovascular Research (VIGOUR) organisation. “Key issues for global cardiovascular medicine.” Lancet (London, England) 374, no. 9689 (August 2009): 508–10. https://doi.org/10.1016/s0140-6736(09)61470-7.
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• Lopes, Renato D., Gail E. Hafley, Keith B. Allen, T Bruce Ferguson, Eric D. Peterson, Robert A. Harrington, Rajendra H. Mehta, et al. “Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery.” N Engl J Med 361, no. 3 (July 16, 2009): 235–44. https://doi.org/10.1056/NEJMoa0900708.
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• Califf, Robert M., Yuliya Lokhnygina, Eric J. Velazquez, John J. V. McMurray, Jeffrey D. Leimberger, Eldrin F. Lewis, Rafael Diaz, Jan Murin, and Marc A. Pfeffer. “Usefulness of beta blockers in high-risk patients after myocardial infarction in conjunction with captopril and/or valsartan (from the VALsartan In Acute Myocardial Infarction [VALIANT] trial).” Am J Cardiol 104, no. 2 (July 15, 2009): 151–57. https://doi.org/10.1016/j.amjcard.2009.03.020.
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• Califf, Robert M. “Rational use of medications: if Canada can't do it ...” Cmaj 181, no. 1–2 (July 7, 2009): 15–16. https://doi.org/10.1503/cmaj.090861.
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• Califf, Robert M. “Angiographic profiles in courage.” Circ Cardiovasc Qual Outcomes 2, no. 4 (July 2009): 292–93. https://doi.org/10.1161/CIRCOUTCOMES.109.883223.
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• Chan, Mark Y., Jie L. Sun, L Kristin Newby, Linda K. Shaw, Min Lin, Eric D. Peterson, Robert M. Califf, David F. Kong, and Matthew T. Roe. “Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction.” Circulation 119, no. 24 (June 23, 2009): 3110–17. https://doi.org/10.1161/CIRCULATIONAHA.108.799981.
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• Harrington, Robert A., Robert M. Califf, Patricia K. Hodgson, Eric D. Peterson, Matthew T. Roe, and Daniel B. Mark. “Careers for clinician investigators.” Circulation 119, no. 22 (June 9, 2009): 2945–50. https://doi.org/10.1161/CIRCULATIONAHA.107.752717.
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• Berry, Colin, Karen S. Pieper, Harvey D. White, Scott D. Solomon, Frans Van de Werf, Eric J. Velazquez, Aldo P. Maggioni, Robert M. Califf, Marc A. Pfeffer, and John J. V. McMurray. “Patients with prior coronary artery bypass grafting have a poor outcome after myocardial infarction: an analysis of the VALsartan in acute myocardial iNfarcTion trial (VALIANT).” Eur Heart J 30, no. 12 (June 2009): 1450–56. https://doi.org/10.1093/eurheartj/ehp102.
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• Eagle, Kim A., Alan T. Hirsch, Robert M. Califf, Mark J. Alberts, P Gabriel Steg, Christopher P. Cannon, Danielle M. Brennan, Deepak L. Bhatt, and Deepak L. REACH Registry Investigators. “Cardiovascular ischemic event rates in outpatients with symptomatic atherothrombosis or risk factors in the united states: insights from the REACH Registry.” Crit Pathw Cardiol 8, no. 2 (June 2009): 91–97. https://doi.org/10.1097/HPC.0b013e3181a84613.
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• Turer, Aslan T., Kenneth W. Mahaffey, Emily Honeycutt, Robert H. Tuttle, Linda K. Shaw, Michael H. Sketch, Peter K. Smith, Robert M. Califf, and John H. Alexander. “Influence of body mass index on the efficacy of revascularization in patients with coronary artery disease.” J Thorac Cardiovasc Surg 137, no. 6 (June 2009): 1468–74. https://doi.org/10.1016/j.jtcvs.2008.11.047.
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• Giugliano, Robert P., Jennifer A. White, Christoph Bode, Paul W. Armstrong, Gilles Montalescot, Basil S. Lewis, Arnoud van ’t Hof, et al. “Early versus delayed, provisional eptifibatide in acute coronary syndromes.” N Engl J Med 360, no. 21 (May 21, 2009): 2176–90. https://doi.org/10.1056/NEJMoa0901316.
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• Giugliano, R. P., J. A. White, C. Bode, P. W. Armstrong, G. Montalescot, B. S. Lewis, A. Van’t Hof, et al. “Early versus delayed, provisional eptifibatide in acute coronary syndromes.” Revista Portuguesa De Cardiologia 28, no. 4 (April 1, 2009): 487–89.
• Califf, Robert M., and Eric D. Peterson. “Public reporting of quality measures what are we trying to accomplish?” J Am Coll Cardiol 53, no. 10 (March 10, 2009): 831–33. https://doi.org/10.1016/j.jacc.2008.10.056.
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• Tricoci, Pierluigi, Joseph M. Allen, Judith M. Kramer, Robert M. Califf, and Sidney C. Smith. “Scientific evidence underlying the ACC/AHA clinical practice guidelines.” Jama 301, no. 8 (February 25, 2009): 831–41. https://doi.org/10.1001/jama.2009.205.
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• Glickman, Seth W., John G. McHutchison, Eric D. Peterson, Charles B. Cairns, Robert A. Harrington, Robert M. Califf, and Kevin A. Schulman. “Ethical and scientific implications of the globalization of clinical research.” N Engl J Med 360, no. 8 (February 19, 2009): 816–23. https://doi.org/10.1056/NEJMsb0803929.
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• Califf, Robert M. “A virtuous cycle to improve hypertension outcomes at a national level: linking public health and individualized medicine.” Hypertension 53, no. 2 (February 2009): 105–7. https://doi.org/10.1161/HYPERTENSIONAHA.108.121608.
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• Ezekowitz, Justin A., Adrian F. Hernandez, Randall C. Starling, Clyde W. Yancy, Barry Massie, James A. Hill, Henry Krum, et al. “Standardizing care for acute decompensated heart failure in a large megatrial: the approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND-HF).” Am Heart J 157, no. 2 (February 2009): 219–28. https://doi.org/10.1016/j.ahj.2008.10.002.
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• Hernandez, Adrian F., Christopher M. O’Connor, Randall C. Starling, Craig J. Reist, Paul W. Armstrong, Kenneth Dickstein, Todd J. Lorenz, et al. “Rationale and design of the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure Trial (ASCEND-HF).” Am Heart J 157, no. 2 (February 2009): 271–77. https://doi.org/10.1016/j.ahj.2008.07.031.
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• Mehta, Rajendra H., Joseph G. Rogers, Vic Hasselblad, Gudaye Tasissa, Cynthia Binanay, Robert M. Califf, Christopher M. O’Connor, and Christopher M. Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) Trial Investigators. “Association of weight change with subsequent outcomes in patients hospitalized with acute decompensated heart failure.” Am J Cardiol 103, no. 1 (January 1, 2009): 76–81. https://doi.org/10.1016/j.amjcard.2008.08.041.
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• Califf, Robert M. “The benefits of moving quality to a national level.” Am Heart J 156, no. 6 (December 2008): 1019–22. https://doi.org/10.1016/j.ahj.2008.09.005.
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• Piccini, Jonathan P., Patrick M. Hranitzky, Rakhi Kilaru, Jean-Lucien Rouleau, Harvey D. White, Philip E. Aylward, Frans Van de Werf, Scott D. Solomon, Robert M. Califf, and Eric J. Velazquez. “Relation of mortality to failure to prescribe beta blockers acutely in patients with sustained ventricular tachycardia and ventricular fibrillation following acute myocardial infarction (from the VALsartan In Acute myocardial iNfarcTion trial [VALIANT] Registry).” Am J Cardiol 102, no. 11 (December 1, 2008): 1427–32. https://doi.org/10.1016/j.amjcard.2008.07.033.
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• Califf, Robert M., and Geoffrey S. Ginsburg. “Organizational improvements to enhance modern clinical epidemiology.” Jama 300, no. 19 (November 19, 2008): 2300–2302. https://doi.org/10.1001/jama.2008.638.
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• Stevenson, Lynne W., Anne S. Hellkamp, Carl V. Leier, George Sopko, Todd Koelling, J Wayne Warnica, William T. Abraham, et al. “Changing preferences for survival after hospitalization with advanced heart failure.” J Am Coll Cardiol 52, no. 21 (November 18, 2008): 1702–8. https://doi.org/10.1016/j.jacc.2008.08.028.
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• Aronow, Herbert D., Robert M. Califf, Robert A. Harrington, Marc Vallee, Carmelo Graffagnino, Ashfaq Shuaib, Desmond J. Fitzgerald, et al. “Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the BRAVO Trial).” Am J Cardiol 102, no. 10 (November 15, 2008): 1285–90. https://doi.org/10.1016/j.amjcard.2008.07.019.
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• O’Connor, Christopher M., Wei Jiang, Maragatha Kuchibhatla, Rajendra H. Mehta, Greg L. Clary, Michael S. Cuffe, Eric J. Christopher, Jude D. Alexander, Robert M. Califf, and Ranga R. Krishnan. “Antidepressant use, depression, and survival in patients with heart failure.” Arch Intern Med 168, no. 20 (November 10, 2008): 2232–37. https://doi.org/10.1001/archinte.168.20.2232.
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• Califf, Robert M., Emma B. Rasiel, and Kevin A. Schulman. “Considerations of net present value in policy making regarding diagnostic and therapeutic technologies.” Am Heart J 156, no. 5 (November 2008): 879–85. https://doi.org/10.1016/j.ahj.2008.06.038.
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• Cannon, Christopher P., Robert P. Giugliano, Michael A. Blazing, Robert A. Harrington, John L. Peterson, Christine McCrary Sisk, John Strony, et al. “Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes.” Am Heart J 156, no. 5 (November 2008): 826–32. https://doi.org/10.1016/j.ahj.2008.07.023.
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• Li, J. S., C. M. Baker-Smith, P. B. Smith, V. Hasselblad, M. D. Murphy, R. M. Califf, and D. K. Benjamin. “Erratum: Racial differences in blood pressure response to angiotensin-converting enzyme inhibitors in children: A meta-analysis (Clinical Pharmacology Therapeutics (2008) 84, (315-319)).” Clinical Pharmacology and Therapeutics 84, no. 5 (November 1, 2008): 636. https://doi.org/10.1038/clpt.2008.180.
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• Mehta, Rajendra H., Gail E. Hafley, C Michael Gibson, Robert A. Harrington, Eric D. Peterson, Michael J. Mack, Nicholas T. Kouchoukos, et al. “Influence of preoperative renal dysfunction on one-year bypass graft patency and two-year outcomes in patients undergoing coronary artery bypass surgery.” J Thorac Cardiovasc Surg 136, no. 5 (November 2008): 1149–55. https://doi.org/10.1016/j.jtcvs.2008.02.085.
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• Novak, James E., Jula K. Inrig, Uptal D. Patel, Robert M. Califf, and Lynda A. Szczech. “Negative trials in nephrology: what can we learn?” Kidney International 74, no. 9 (November 2008): 1121–27. https://doi.org/10.1038/ki.2008.286.
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• Allen, Larry A., Joseph G. Rogers, J Wayne Warnica, Thomas G. Disalvo, Gudaye Tasissa, Cynthia Binanay, Christopher M. O’Connor, et al. “High mortality without ESCAPE: the registry of heart failure patients receiving pulmonary artery catheters without randomization.” J Card Fail 14, no. 8 (October 2008): 661–69. https://doi.org/10.1016/j.cardfail.2008.05.004.
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• Baker-Smith, Carissa M., Daniel K. Benjamin, Henry G. Grabowski, Elizabeth D. Reid, Barry Mangum, John V. Goldsmith, M Dianne Murphy, et al. “The economic returns of pediatric clinical trials of antihypertensive drugs.” Am Heart J 156, no. 4 (October 2008): 682–88. https://doi.org/10.1016/j.ahj.2008.05.001.
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• Bethel, M Angelyn, Rury Holman, Steven M. Haffner, Robert M. Califf, Alice Huntsman-Labed, Tsushung A. Hua, and John McMurray. “Determining the most appropriate components for a composite clinical trial outcome.” Am Heart J 156, no. 4 (October 2008): 633–40. https://doi.org/10.1016/j.ahj.2008.05.018.
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• Califf, Robert M., Mitradev Boolell, Steven M. Haffner, M Angelyn Bethel, John McMurray, Anil Duggal, Rury R. Holman, and Rury R. NAVIGATOR Study Group. “Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial.” Am Heart J 156, no. 4 (October 2008): 623–32. https://doi.org/10.1016/j.ahj.2008.05.017.
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• Peto, Richard, Jonathan Emberson, Martin Landray, Colin Baigent, Rory Collins, Robert Clare, and Robert Califf. “Analyses of cancer data from three ezetimibe trials.” N Engl J Med 359, no. 13 (September 25, 2008): 1357–66. https://doi.org/10.1056/NEJMsa0806603.
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• Brilakis, Emmanouil S., James A. de Lemos, Christopher P. Cannon, Stephen D. Wiviott, Sabina A. Murphy, David A. Morrow, Marc S. Sabatine, et al. “Outcomes of patients with acute coronary syndrome and previous coronary artery bypass grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials).” Am J Cardiol 102, no. 5 (September 1, 2008): 552–58. https://doi.org/10.1016/j.amjcard.2008.04.024.
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• Drazner, Mark H., Anne S. Hellkamp, Carl V. Leier, Monica R. Shah, Leslie W. Miller, Stuart D. Russell, James B. Young, Robert M. Califf, and Anju Nohria. “Value of clinician assessment of hemodynamics in advanced heart failure: the ESCAPE trial.” Circ Heart Fail 1, no. 3 (September 2008): 170–77. https://doi.org/10.1161/CIRCHEARTFAILURE.108.769778.
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• Li, J. S., C. M. Baker-Smith, P. B. Smith, V. Hasselblad, M. D. Murphy, R. M. Califf, and D. K. Benjamin. “Racial differences in blood pressure response to angiotensin-converting enzyme inhibitors in children: a meta-analysis.” Clinical Pharmacology and Therapeutics 84, no. 3 (September 2008): 315–19. https://doi.org/10.1038/clpt.2008.113.
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• Payne, K. A., J. J. Caro, W. L. Daley, Z. M. Khan, K. J. Ishak, K. Stark, D. Purkayastha, et al. “The design of an observational study of hypertension management, adherence and pressure control in Blood Pressure Success Zone Program participants.” Int J Clin Pract 62, no. 9 (September 2008): 1313–21. https://doi.org/10.1111/j.1742-1241.2008.01840.x.
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• Reed, Shelby D., Kevin J. Anstrom, Damon M. Seils, Robert M. Califf, and Kevin A. Schulman. “Use of larger versus smaller drug-safety databases before regulatory approval: the trade-offs.” Health Aff (Millwood) 27, no. 5 (September 2008): w360–70. https://doi.org/10.1377/hlthaff.27.5.w360.
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• Smith, P Brian, Daniel K. Benjamin, M Dianne Murphy, Rosemary Johann-Liang, Solomon Iyasu, Barbara Gould, Robert M. Califf, Jennifer S. Li, and William Rodriguez. “Safety monitoring of drugs receiving pediatric marketing exclusivity.” Pediatrics 122, no. 3 (September 2008): e628–33. https://doi.org/10.1542/peds.2008-0585.
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• Szczech, Lynda A., Huiman X. Barnhart, Jula K. Inrig, Donal N. Reddan, Shelly Sapp, Robert M. Califf, Uptal D. Patel, and Ajay K. Singh. “Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes.” Kidney Int 74, no. 6 (September 2008): 791–98. https://doi.org/10.1038/ki.2008.295.
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• Verma, Anil, Alessandra Meris, Hicham Skali, Jalal K. Ghali, J Malcolm O. Arnold, Mikhail Bourgoun, Eric J. Velazquez, et al. “Prognostic implications of left ventricular mass and geometry following myocardial infarction: the VALIANT (VALsartan In Acute myocardial iNfarcTion) Echocardiographic Study.” Jacc Cardiovasc Imaging 1, no. 5 (September 2008): 582–91. https://doi.org/10.1016/j.jcmg.2008.05.012.
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• Yau, James M., John H. Alexander, Gail Hafley, Kenneth W. Mahaffey, Michael J. Mack, Nicholas Kouchoukos, Abhinav Goyal, et al. “Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV).” Am J Cardiol 102, no. 5 (September 1, 2008): 546–51. https://doi.org/10.1016/j.amjcard.2008.04.069.
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• Anstrom, Kevin J., David F. Kong, Linda K. Shaw, Robert M. Califf, Judith M. Kramer, Eric D. Peterson, Sunil V. Rao, et al. “Long-term clinical outcomes following coronary stenting.” Arch Intern Med 168, no. 15 (August 11, 2008): 1647–55. https://doi.org/10.1001/archinte.168.15.1647.
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• Califf, Robert M., and Judith M. Kramer. “The balance of benefit and safety of rosiglitazone: important lessons for our system of drug development and postmarketing assessment.” Pharmacoepidemiol Drug Saf 17, no. 8 (August 2008): 782–86. https://doi.org/10.1002/pds.1617.
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• Chan, Mark Y., Kenneth W. Mahaffey, Lena J. Sun, Karen S. Pieper, Harvey D. White, Philip E. Aylward, James J. Ferguson, Robert M. Califf, and Matthew T. Roe. “Prevalence, predictors, and impact of conservative medical management for patients with non-ST-segment elevation acute coronary syndromes who have angiographically documented significant coronary disease.” Jacc Cardiovasc Interv 1, no. 4 (August 2008): 369–78. https://doi.org/10.1016/j.jcin.2008.03.019.
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• Lopes, Renato D., Karen P. Alexander, Gretchen Marcucci, Harvey D. White, Sarah Spinler, Jacques Col, Philip E. Aylward, Robert M. Califf, and Kenneth W. Mahaffey. “Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial.” Eur Heart J 29, no. 15 (August 2008): 1827–33. https://doi.org/10.1093/eurheartj/ehn236.
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• Rao, Sunil V., Robert M. Califf, Judith M. Kramer, Eric D. Peterson, Thomas P. Gross, Carl J. Pepine, David O. Williams, et al. “Postmarket evaluation of breakthrough technologies.” Am Heart J 156, no. 2 (August 2008): 201–8. https://doi.org/10.1016/j.ahj.2008.01.036.
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• Leung, Steve, Dianne Gallup, Kenneth W. Mahaffey, Marc Cohen, Elliott M. Antman, Shaun G. Goodman, Robert A. Harrington, et al. “Smoking status and antithrombin therapy in patients with non-ST-segment elevation acute coronary syndrome.” Am Heart J 156, no. 1 (July 2008): 177–84. https://doi.org/10.1016/j.ahj.2008.02.002.
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• Roe, Matthew T., Anita Y. Chen, Elizabeth R. Delong, William E. Boden, James E. Calvin, Charles B. Cairns, Sidney C. Smith, et al. “Patterns of transfer for patients with non-ST-segment elevation acute coronary syndrome from community to tertiary care hospitals.” Am Heart J 156, no. 1 (July 2008): 185–92. https://doi.org/10.1016/j.ahj.2008.01.033.
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• Piccini, Jonathan P., Manesh R. Patel, Kenneth W. Mahaffey, Keith A. A. Fox, and Robert M. Califf. “Rivaroxaban, an oral direct factor Xa inhibitor.” Expert Opin Investig Drugs 17, no. 6 (June 2008): 925–37. https://doi.org/10.1517/13543784.17.6.925.
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• Prisant, L Michael, Kevin L. Thomas, Eldrin F. Lewis, Zhen Huang, Gary S. Francis, W Douglas Weaver, Marc A. Pfeffer, John J. V. McMurray, Robert M. Califf, and Eric J. Velazquez. “Racial analysis of patients with myocardial infarction complicated by heart failure and/or left ventricular dysfunction treated with valsartan, captopril, or both.” J Am Coll Cardiol 51, no. 19 (May 13, 2008): 1865–71. https://doi.org/10.1016/j.jacc.2007.12.050.
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• Weinfurt, Kevin P., Damon M. Seils, Janice P. Tzeng, Li Lin, Kevin A. Schulman, and Robert M. Califf. “Consistency of financial interest disclosures in the biomedical literature: the case of coronary stents.” Plos One 3, no. 5 (May 7, 2008): e2128. https://doi.org/10.1371/journal.pone.0002128.
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• Chew, Derek P., Kenneth W. Mahaffey, Harvey D. White, Zhen Huang, James W. Hoekstra, James J. Ferguson, Robert M. Califf, and Philip E. Aylward. “Coronary artery bypass surgery in patients with acute coronary syndromes is difficult to predict.” Am Heart J 155, no. 5 (May 2008): 841–47. https://doi.org/10.1016/j.ahj.2007.12.002.
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• Jackson, Kevin, Bernard J. Gersh, Norman Stockbridge, Thomas R. Fleming, Robert Temple, Robert M. Califf, Stuart J. Connolly, Lars Wallentin, Christopher B. Granger, and Christopher B. Duke Clinical Research Institute/American Heart Journal Expert Meeting on Antithrombotic Drug Development for Atrial Fibrillation. “Antithrombotic drug development for atrial fibrillation: proceedings, Washington, DC, July 25-27, 2005.” Am Heart J 155, no. 5 (May 2008): 829–40. https://doi.org/10.1016/j.ahj.2008.01.023.
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• Klein, Liviu, Barry M. Massie, Jeffrey D. Leimberger, Christopher M. O’Connor, Ileana L. Piña, Kirkwood F. Adams, Robert M. Califf, Mihai Gheorghiade, and Mihai OPTIME-CHF Investigators. “Admission or changes in renal function during hospitalization for worsening heart failure predict postdischarge survival: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF).” Circ Heart Fail 1, no. 1 (May 2008): 25–33. https://doi.org/10.1161/CIRCHEARTFAILURE.107.746933.
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• Thune, J. J., J. Signorovitch, L. Kober, E. J. Velazquez, J. J. V. McMurray, R. M. Califf, A. P. Maggioni, et al. “Response to The J-point revisited.” Hypertension 51, no. 5 (May 1, 2008). https://doi.org/10.1161/HYPERTENSIONAHA.108.109975.
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• Anavekar, Nagesh S., Scott D. Solomon, John J. V. McMurray, Aldo Maggioni, Jean Lucien Rouleau, Robert Califf, Harvey White, Lars Kober, Eric Velazquez, and Marc A. Pfeffer. “Comparison of renal function and cardiovascular risk following acute myocardial infarction in patients with and without diabetes mellitus.” Am J Cardiol 101, no. 7 (April 1, 2008): 925–29. https://doi.org/10.1016/j.amjcard.2007.11.037.
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• Anderson, Rachel E., Marc A. Pfeffer, Jens Jakob Thune, John J. V. McMurray, Robert M. Califf, Eric Velazquez, Harvey D. White, et al. “High-risk myocardial infarction in the young: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial.” Am Heart J 155, no. 4 (April 2008): 706–11. https://doi.org/10.1016/j.ahj.2007.11.016.
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• Benjamin, Daniel K., P Brian Smith, Pravin Jadhav, Jogarao V. Gobburu, M Dianne Murphy, Vic Hasselblad, Carissa Baker-Smith, Robert M. Califf, and Jennifer S. Li. “Pediatric antihypertensive trial failures: analysis of end points and dose range.” Hypertension 51, no. 4 (April 2008): 834–40. https://doi.org/10.1161/HYPERTENSIONAHA.107.108886.
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• Best, Patricia J. M., Steven R. Steinhubl, Peter B. Berger, Arijit Dasgupta, Danielle M. Brennan, Lynda A. Szczech, Robert M. Califf, Eric J. Topol, and Eric J. CREDO Investigators. “The efficacy and safety of short- and long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial.” Am Heart J 155, no. 4 (April 2008): 687–93. https://doi.org/10.1016/j.ahj.2007.10.046.
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• Konstance, Richard P., Eric L. Eisenstein, Kevin J. Anstrom, Linda K. Shaw, Robert M. Califf, Robert A. Harrington, David B. Matchar, Kevin A. Schulman, and David F. Kong. “Outcomes of second revascularization procedures after stent implantation.” J Med Syst 32, no. 2 (April 2008): 177–86. https://doi.org/10.1007/s10916-007-9120-x.
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• Mehta, Rajendra H., Sunil V. Rao, E Magnus Ohman, Eric R. Bates, Gretchen Marcucci, Min Zhang, Karen S. Pieper, et al. “Variation in the use of stress testing and outcomes in patients with non-ST-elevation acute coronary syndromes: insights from GUSTO IIb.” Eur Heart J 29, no. 7 (April 2008): 880–87. https://doi.org/10.1093/eurheartj/ehn100.
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• Michener, J Lloyd, Susan Yaggy, Michelle Lyn, Samuel Warburton, Mary Champagne, MaryAnn Black, Michael Cuffe, et al. “Improving the health of the community: Duke's experience with community engagement.” Acad Med 83, no. 4 (April 2008): 408–13. https://doi.org/10.1097/ACM.0b013e3181668450.
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• Mielniczuk, Lisa M., Marc A. Pfeffer, Eldrin F. Lewis, Michael A. Blazing, James A. de Lemos, Amy Shui, Satish Mohanavelu, Robert M. Califf, and Eugene Braunwald. “Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome.” Am Heart J 155, no. 4 (April 2008): 725–31. https://doi.org/10.1016/j.ahj.2007.11.031.
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• Nohria, Anju, Vic Hasselblad, Amanda Stebbins, Daniel F. Pauly, Gregg C. Fonarow, Monica Shah, Clyde W. Yancy, Robert M. Califf, Lynne W. Stevenson, and James A. Hill. “Cardiorenal interactions: insights from the ESCAPE trial.” J Am Coll Cardiol 51, no. 13 (April 1, 2008): 1268–74. https://doi.org/10.1016/j.jacc.2007.08.072.
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• Shah, Monica R., David J. Whellan, Eric D. Peterson, Anju Nohria, Vic Hasselblad, Zhenyi Xue, Margaret T. Bowers, Christopher M. O’Connor, Robert M. Califf, and Lynne W. Stevenson. “Delivering heart failure disease management in 3 tertiary care centers: key clinical components and venues of care.” Am Heart J 155, no. 4 (April 2008): 764.e1-764.e5. https://doi.org/10.1016/j.ahj.2007.12.026.
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• Smith, P Brian, Jennifer S. Li, M Dianne Murphy, Robert M. Califf, and Daniel K. Benjamin. “Safety of placebo controls in pediatric hypertension trials.” Hypertension 51, no. 4 (April 2008): 829–33. https://doi.org/10.1161/HYPERTENSIONAHA.107.104950.
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• Anavekar, Nagesh S., Hicham Skali, Mikhail Bourgoun, Jalal K. Ghali, Lars Kober, Aldo P. Maggioni, John J. V. McMurray, et al. “Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study).” Am J Cardiol 101, no. 5 (March 1, 2008): 607–12. https://doi.org/10.1016/j.amjcard.2007.09.115.
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• Jolicoeur, E Marc, E Magnus Ohman, Robert Temple, Norman Stockbridge, Sidney Smith, Daniel Mark, Robert M. Califf, et al. “Clinical and research issues regarding chronic advanced coronary artery disease part II: Trial design, outcomes, and regulatory issues.” Am Heart J 155, no. 3 (March 2008): 435–44. https://doi.org/10.1016/j.ahj.2007.12.005.
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• Lewis, Eldrin F., Eric J. Velazquez, Scott D. Solomon, Anne S. Hellkamp, John J. V. McMurray, Jasmine Mathias, Jean-Lucien Rouleau, et al. “Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction: a VALIANT study.” Eur Heart J 29, no. 6 (March 2008): 748–56. https://doi.org/10.1093/eurheartj/ehn062.
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• Mahaffey, Kenneth W., Qinghong Yang, Karen S. Pieper, Elliott M. Antman, Harvey D. White, Shaun G. Goodman, Marc Cohen, et al. “Prediction of one-year survival in high-risk patients with acute coronary syndromes: results from the SYNERGY trial.” J Gen Intern Med 23, no. 3 (March 2008): 310–16. https://doi.org/10.1007/s11606-007-0498-4.
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• Chew, Derek P., Zhen Huang, Karen S. Pieper, Harvey White, Kenneth W. Mahaffey, James J. Ferguson, Robert M. Califf, and Philip G. Aylward. “Patients with non-ST-elevation acute coronary syndromes undergoing coronary artery bypass grafting in the modern era of antithrombotic therapy.” Am Heart J 155, no. 2 (February 2008): 239–44. https://doi.org/10.1016/j.ahj.2007.10.002.
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• Magee, Mitchell J., John H. Alexander, Gail Hafley, T Bruce Ferguson, C Michael Gibson, Robert A. Harrington, Eric D. Peterson, et al. “Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV.” Ann Thorac Surg 85, no. 2 (February 2008): 494–99. https://doi.org/10.1016/j.athoracsur.2007.10.008.
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• Olenchock, Stephen A., Dimitri Karmpaliotis, William J. Gibson, Sabina A. Murphy, Matthew C. Southard, Lauren Ciaglo, Jacqueline Buros, et al. “Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters.” Ann Thorac Surg 85, no. 2 (February 2008): 520–24. https://doi.org/10.1016/j.athoracsur.2007.10.061.
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• Rao, Sunil V., Padma R. Kaul, Lawrence Liao, Paul W. Armstrong, E Magnus Ohman, Christopher B. Granger, Robert M. Califf, Robert A. Harrington, Eric L. Eisenstein, and Daniel B. Mark. “Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes.” Am Heart J 155, no. 2 (February 2008): 369–74. https://doi.org/10.1016/j.ahj.2007.10.014.
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• Berger, Jeffrey S., Amanda Stebbins, Christopher B. Granger, Eric M. Ohman, Paul W. Armstrong, Frans Van de Werf, Harvey D. White, et al. “Initial aspirin dose and outcome among ST-elevation myocardial infarction patients treated with fibrinolytic therapy.” Circulation 117, no. 2 (January 15, 2008): 192–99. https://doi.org/10.1161/CIRCULATIONAHA.107.729558.
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• Eisenstein, Eric L., Rory Collins, Beena S. Cracknell, Oscar Podesta, Elizabeth D. Reid, Peter Sandercock, Yuriy Shakhov, et al. “Sensible approaches for reducing clinical trial costs.” Clin Trials 5, no. 1 (2008): 75–84. https://doi.org/10.1177/1740774507087551.
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• Harrington, Robert A., Vic Hasselblad, and Robert M. Califf. “Defining and utilizing surrogates in the evaluation of coronary stents: what do we really want and need to know?” J Am Coll Cardiol 51, no. 1 (January 1, 2008): 33–36. https://doi.org/10.1016/j.jacc.2007.08.051.
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• Rao, Sunil V., Karen Chiswell, Jie-Lena Sun, Christopher B. Granger, L Kristin Newby, Frans Van de Werf, Harvey D. White, Paul W. Armstong, Robert M. Califf, and Robert A. Harrington. “International variation in the use of blood transfusion in patients with non-ST-segment elevation acute coronary syndromes.” Am J Cardiol 101, no. 1 (January 1, 2008): 25–29. https://doi.org/10.1016/j.amjcard.2007.07.042.
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• Thomas, Kevin L., Sana M. Al-Khatib, Yuliya Lokhnygina, Scott D. Solomon, Lars Kober, John J. V. McMurray, Robert M. Califf, and Eric J. Velazquez. “Amiodarone use after acute myocardial infarction complicated by heart failure and/or left ventricular dysfunction may be associated with excess mortality.” Am Heart J 155, no. 1 (January 2008): 87–93. https://doi.org/10.1016/j.ahj.2007.09.010.
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• Thune, Jens J., James Signorovitch, Lars Kober, Eric J. Velazquez, John J. V. McMurray, Robert M. Califf, Aldo P. Maggioni, et al. “Effect of antecedent hypertension and follow-up blood pressure on outcomes after high-risk myocardial infarction.” Hypertension 51, no. 1 (January 2008): 48–54. https://doi.org/10.1161/HYPERTENSIONAHA.107.093682.
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• Yusuf, Salim, Jackie Bosch, Philip J. Devereaux, Rory Collins, Colin Baigent, Christopher Granger, Robert Califf, and Robert Temple. “Sensible guidelines for the conduct of large randomized trials.” Clin Trials 5, no. 1 (2008): 38–39. https://doi.org/10.1177/1740774507088099.
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• Tricoci, Pierluigi, Yuliya Lokhnygina, Lisa G. Berdan, Steven R. Steinhubl, Dietrich C. Gulba, Harvey D. White, Neal S. Kleiman, et al. “Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial.” Circulation 116, no. 23 (December 4, 2007): 2669–77. https://doi.org/10.1161/CIRCULATIONAHA.107.690081.
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• Al-Khatib, Sana M., Linda K. Shaw, Christopher O’Connor, Melissa Kong, and Robert M. Califf. “Incidence and predictors of sudden cardiac death in patients with diastolic heart failure.” J Cardiovasc Electrophysiol 18, no. 12 (December 2007): 1231–35. https://doi.org/10.1111/j.1540-8167.2007.00957.x.
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• Antman, E. M., R. M. Califf, and J. Kupersmith. “Tools for Assessment of Cardiovascular Tests and Therapies,” December 1, 2007, 1–34. https://doi.org/10.1016/B978-1-4160-3358-5.50007-3.
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• Califf, R. M. “The cycle of quality as a model for improving health outcomes in the treatment of hypertension.” European Heart Journal, Supplement 9, no. B (December 1, 2007). https://doi.org/10.1093/eurheartj/sum002.
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• Califf, R. M. “Large clinical trials and registries-clinical research institutes,” December 1, 2007, 237–63. https://doi.org/10.1016/B978-012369440-9/50022-0.
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• Lemos, James A. de, David A. Morrow, Michael A. Blazing, Petr Jarolim, Stephen D. Wiviott, Marc S. Sabatine, Robert M. Califf, and Eugene Braunwald. “Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: results from the A to Z trial.” J Am Coll Cardiol 50, no. 22 (November 27, 2007): 2117–24. https://doi.org/10.1016/j.jacc.2007.06.057.
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• Califf, Robert M., Rajendra H. Mehta, and Eric D. Peterson. “Clinical quality in non-ST-elevation acute coronary syndromes.” Am J Med 120, no. 11 (November 2007): 930–35. https://doi.org/10.1016/j.amjmed.2006.10.016.
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• Mark, Daniel B., Frans J. Van de Werf, R John Simes, Harvey D. White, Lars C. Wallentin, Robert M. Califf, Paul W. Armstrong, and Paul W. VIGOUR Group. “Cardiovascular disease on a global scale: defining the path forward for research and practice.” Eur Heart J 28, no. 21 (November 2007): 2678–84. https://doi.org/10.1093/eurheartj/ehm411.
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• Shah, Monica R., Vic Hasselblad, Gudaye Tasissa, Robert H. Christenson, Cynthia Binanay, Christopher M. O’Connor, E Magnus Ohman, Lynne W. Stevenson, and Robert M. Califf. “Rapid assay brain natriuretic peptide and troponin I in patients hospitalized with decompensated heart failure (from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness Trial).” Am J Cardiol 100, no. 9 (November 1, 2007): 1427–33. https://doi.org/10.1016/j.amjcard.2007.06.035.
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• Singh, Mandeep, Jennifer White, David Hasdai, Patricia K. Hodgson, Peter B. Berger, Eric J. Topol, Robert M. Califf, and David R. Holmes. “Long-term outcome and its predictors among patients with ST-segment elevation myocardial infarction complicated by shock: insights from the GUSTO-I trial.” J Am Coll Cardiol 50, no. 18 (October 30, 2007): 1752–58. https://doi.org/10.1016/j.jacc.2007.04.101.
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• Bennett-Guerrero, Elliott, Tim H. Veldman, Allan Doctor, Marilyn J. Telen, Thomas L. Ortel, T Scott Reid, Melissa A. Mulherin, et al. “Evolution of adverse changes in stored RBCs.” Proc Natl Acad Sci U S A 104, no. 43 (October 23, 2007): 17063–68. https://doi.org/10.1073/pnas.0708160104.
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• Hasselblad, Vic, Wendy Gattis Stough, Monica R. Shah, Yuliya Lokhnygina, Christopher M. O’Connor, Robert M. Califf, and Kirkwood F. Adams. “Relation between dose of loop diuretics and outcomes in a heart failure population: results of the ESCAPE trial.” Eur J Heart Fail 9, no. 10 (October 2007): 1064–69. https://doi.org/10.1016/j.ejheart.2007.07.011.
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• Mehta, Rajendra H., Adam B. Greenbaum, Yuliya Lokhnygina, L Kristin Newby, Frans Van De Werf, Paul W. Armstrong, Karen S. Pieper, Robert M. Califf, Christopher B. Granger, and Robert A. Harrington. “Timing of death and myocardial infarction in patients with non-ST elevation acute coronary syndromes: insights from randomized clinical trials.” J Interv Cardiol 20, no. 5 (October 2007): 299–306. https://doi.org/10.1111/j.1540-8183.2007.00277.x.
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• Murphy, Sabina A., Christopher P. Cannon, Stephen D. Wiviott, James A. de Lemos, Michael A. Blazing, Carolyn H. McCabe, Robert M. Califf, and Eugene Braunwald. “Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials).” Am J Cardiol 100, no. 7 (October 1, 2007): 1047–51. https://doi.org/10.1016/j.amjcard.2007.04.053.
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• Anderson, Jeffrey L., Cynthia D. Adams, Elliott M. Antman, Charles R. Bridges, Robert M. Califf, Donald E. Casey, William E. Chavey, et al. “ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine.” Circulation 116, no. 7 (August 14, 2007): e148–304. https://doi.org/10.1161/CIRCULATIONAHA.107.181940.
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• Anderson, Jeffrey L., Cynthia D. Adams, Elliott M. Antman, Charles R. Bridges, Robert M. Califf, Donald E. Casey, William E. Chavey, et al. “ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine.” J Am Coll Cardiol 50, no. 7 (August 14, 2007): e1–157. https://doi.org/10.1016/j.jacc.2007.02.013.
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• Tilson, H. H., L. K. Madre, and R. M. Califf. “Role of the centers for education and research on therapeutics (CERTs) in pharmacovigilance and proper use of therapeutics.” Clinical Pharmacology and Therapeutics 82, no. 2 (August 2007): 118–21. https://doi.org/10.1038/sj.clpt.6100251.
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• Westerhout, Cynthia M., Judy Gnarpe, Wei-Ching Chang, Susan FitzPatrick, Elliot S. Barnathan, Eric Boersma, Robert M. Califf, et al. “No prognostic significance of chronic infection with Chlamydia pneumoniae in acute coronary syndromes: insights from the Global Utilization of Strategies to Open Occluded Arteries IV Acute Coronary Syndromes trial.” Am Heart J 154, no. 2 (August 2007): 306–12. https://doi.org/10.1016/j.ahj.2007.04.010.
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• Wong, Cheuk-Kit, L Kristin Newby, Manju V. Bhapker, Phil E. Aylward, Matthias Pfisterer, Karen P. Alexander, Paul W. Armstrong, et al. “Use of evidence-based medicine for acute coronary syndromes in the elderly and very elderly: insights from the Sibrafiban vs aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes trials.” Am Heart J 154, no. 2 (August 2007): 313–21. https://doi.org/10.1016/j.ahj.2007.04.031.
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• Li, Jennifer S., Eric Yow, Katherine Y. Berezny, John F. Rhodes, Paula M. Bokesch, John R. Charpie, Geoffrey A. Forbus, et al. “Clinical outcomes of palliative surgery including a systemic-to-pulmonary artery shunt in infants with cyanotic congenital heart disease: does aspirin make a difference?” Circulation 116, no. 3 (July 17, 2007): 293–97. https://doi.org/10.1161/CIRCULATIONAHA.106.652172.
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• Barbagelata, Alejandro, Eduardo R. Perna, Peter Clemmensen, Barry F. Uretsky, Juan P Cimbaro Canella, Robert M. Califf, Christopher B. Granger, George L. Adams, Ramanna Merla, and Yochai Birnbaum. “Time to reperfusion in acute myocardial infarction. It is time to reduce it!.” J Electrocardiol 40, no. 3 (July 2007): 257–64. https://doi.org/10.1016/j.jelectrocard.2007.01.007.
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• Jiang, Wei, Maragatha Kuchibhatla, Greg L. Clary, Michael S. Cuffe, Eric J. Christopher, Jude D. Alexander, Robert M. Califf, Ranga R. Krishnan, and Christopher M. O’Connor. “Relationship between depressive symptoms and long-term mortality in patients with heart failure.” Am Heart J 154, no. 1 (July 2007): 102–8. https://doi.org/10.1016/j.ahj.2007.03.043.
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• Mark, D. B., P. Hodgson, and R. M. Califf. “What we publish in the American Heart Journal and why.” American Heart Journal 154, no. 1 (July 1, 2007): 1–2. https://doi.org/10.1016/j.ahj.2007.05.002.
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• Al-Khatib, Sana M., Gillian D. Sanders, J Thomas Bigger, Alfred E. Buxton, Robert M. Califf, Mark Carlson, Anne Curtis, et al. “Preventing tomorrow's sudden cardiac death today: part I: Current data on risk stratification for sudden cardiac death.” Am Heart J 153, no. 6 (June 2007): 941–50. https://doi.org/10.1016/j.ahj.2007.03.003.
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• Sanders, Gillian D., Sana M. Al-Khatib, Elise Berliner, J Thomas Bigger, Alfred E. Buxton, Robert M. Califf, Mark Carlson, et al. “Preventing tomorrow's sudden cardiac death today: part II: Translating sudden cardiac death risk assessment strategies into practice and policy.” Am Heart J 153, no. 6 (June 2007): 951–59. https://doi.org/10.1016/j.ahj.2007.03.002.
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• Mehta, Rajendra H., Eric D. Peterson, and Robert M. Califf. “Performance measures have a major effect on cardiovascular outcomes: a review.” Am J Med 120, no. 5 (May 2007): 398–402. https://doi.org/10.1016/j.amjmed.2006.12.018.
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• Miller, Chadwick D., Anindita Banerjee, Kenneth W. Mahaffey, Michael C. Kontos, Gregory Fermann, Charles V. Pollack, Elliott Antman, et al. “Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trial.” Eur Heart J 28, no. 9 (May 2007): 1079–84. https://doi.org/10.1093/eurheartj/ehm016.
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• Rao, Sunil V., John A. Eikelboom, Christopher B. Granger, Robert A. Harrington, Robert M. Califf, and Jean-Pierre Bassand. “Bleeding and blood transfusion issues in patients with non-ST-segment elevation acute coronary syndromes.” Eur Heart J 28, no. 10 (May 2007): 1193–1204. https://doi.org/10.1093/eurheartj/ehm019.
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• Hernández, Adrián V., Cynthia M. Westerhout, Ewout W. Steyerberg, John P. A. Ioannidis, Héctor Bueno, Harvey White, Pierre Theroux, et al. “Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups.” Heart 93, no. 4 (April 2007): 450–55. https://doi.org/10.1136/hrt.2006.098657.
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• Turer, Aslan T., Kenneth W. Mahaffey, Kate L. Compton, Robert M. Califf, and Kevin A. Schulman. “Publication or presentation of results from multicenter clinical trials: evidence from an academic medical center.” Am Heart J 153, no. 4 (April 2007): 674–80. https://doi.org/10.1016/j.ahj.2007.01.005.
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• Mehta, Rajendra H., Robert M. Califf, Qinghong Yang, Karen S. Pieper, Harvey D. White, E Magnus Ohman, Robert A. Harrington, and Christopher B. Granger. “Impact of initial heart rate and systolic blood pressure on relation of age and mortality among fibrinolytic-treated patients with acute ST-elevation myocardial infarction presenting with cardiogenic shock.” Am J Cardiol 99, no. 6 (March 15, 2007): 793–96. https://doi.org/10.1016/j.amjcard.2006.10.035.
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• Califf, R. M., and L. K. Madre. “A View from Academia,” March 14, 2007, 67–76. https://doi.org/10.1002/9780470059876.ch6.
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• Bethel, M Angelyn, and Robert M. Califf. “Role of lifestyle and oral anti-diabetic agents to prevent type 2 diabetes mellitus and cardiovascular disease.” Am J Cardiol 99, no. 5 (March 1, 2007): 726–31. https://doi.org/10.1016/j.amjcard.2006.09.122.
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• Goyal, Abhinav, John H. Alexander, Gail E. Hafley, Stacy H. Graham, Rajendra H. Mehta, Michael J. Mack, Randall K. Wolf, et al. “Outcomes associated with the use of secondary prevention medications after coronary artery bypass graft surgery.” Ann Thorac Surg 83, no. 3 (March 2007): 993–1001. https://doi.org/10.1016/j.athoracsur.2006.10.046.
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• Rankin, J Scott, Robert H. Tuttle, Andrew S. Wechsler, Tracey L. Teichmann, Donald D. Glower, and Robert M. Califf. “Techniques and benefits of multiple internal mammary artery bypass at 20 years of follow-up.” Ann Thorac Surg 83, no. 3 (March 2007): 1008–14. https://doi.org/10.1016/j.athoracsur.2006.10.032.
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• Stephenson, Kent, Hicham Skali, John J. V. McMurray, Eric J. Velazquez, Philip G. Aylward, Lars Kober, Frans Van de Werf, et al. “Long-term outcomes of left bundle branch block in high-risk survivors of acute myocardial infarction: the VALIANT experience.” Heart Rhythm 4, no. 3 (March 2007): 308–13. https://doi.org/10.1016/j.hrthm.2006.11.021.
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• Wollert, Kai C., Tibor Kempf, Timo Peter, Sylvia Olofsson, Stefan James, Nina Johnston, Bertil Lindahl, et al. “Prognostic value of growth-differentiation factor-15 in patients with non-ST-elevation acute coronary syndrome.” Circulation 115, no. 8 (February 27, 2007): 962–71. https://doi.org/10.1161/CIRCULATIONAHA.106.650846.
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• Li, Jennifer S., Eric L. Eisenstein, Henry G. Grabowski, Elizabeth D. Reid, Barry Mangum, Kevin A. Schulman, John V. Goldsmith, M Dianne Murphy, Robert M. Califf, and Daniel K. Benjamin. “Economic return of clinical trials performed under the pediatric exclusivity program.” Jama 297, no. 5 (February 7, 2007): 480–88. https://doi.org/10.1001/jama.297.5.480.
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• Echols, Melvin R., Kenneth W. Mahaffey, Anindita Banerjee, Karen S. Pieper, Amanda Stebbins, Alexandra Lansky, Mauricio G. Cohen, et al. “Racial differences among high-risk patients presenting with non-ST-segment elevation acute coronary syndromes (results from the SYNERGY trial).” Am J Cardiol 99, no. 3 (February 1, 2007): 315–21. https://doi.org/10.1016/j.amjcard.2006.08.031.
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• Mahaffey, Kenneth W., Matthew T. Roe, Rakhi Kilaru, John H. Alexander, Frans Van de Werf, Robert M. Califf, Maarten L. Simoons, Eric J. Topol, and Robert A. Harrington. “Creatine kinase-MB elevation after coronary artery bypass grafting surgery in patients with non-ST-segment elevation acute coronary syndromes predict worse outcomes: results from four large clinical trials.” Eur Heart J 28, no. 4 (February 2007): 425–32. https://doi.org/10.1093/eurheartj/ehl483.
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• Mehta, Rajendra H., Robert M. Califf, Jyotsna Garg, Harvey D. White, Frans Van de Werf, Paul W. Armstrong, Karen S. Pieper, Eric J. Topol, and Christopher B. Granger. “The impact of anthropomorphic indices on clinical outcomes in patients with acute ST-elevation myocardial infarction.” Eur Heart J 28, no. 4 (February 2007): 415–24. https://doi.org/10.1093/eurheartj/ehl329.
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• Eisenstein, Eric L., Kevin J. Anstrom, David F. Kong, Linda K. Shaw, Robert H. Tuttle, Daniel B. Mark, Judith M. Kramer, et al. “Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation.” Jama 297, no. 2 (January 10, 2007): 159–68. https://doi.org/10.1001/jama.297.2.joc60179.
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• Califf, Robert M., Robert A. Harrington, Leanne K. Madre, Eric D. Peterson, Deborah Roth, and Kevin A. Schulman. “Curbing the cardiovascular disease epidemic: aligning industry, government, payers, and academics.” Health Aff (Millwood) 26, no. 1 (January 2007): 62–74. https://doi.org/10.1377/hlthaff.26.1.62.
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• Califf, Robert M., and Robert M. CERTs Benefit Assessment Workshop Participants. “Benefit assessment of therapeutic products: the Centers for Education and Research on Therapeutics.” Pharmacoepidemiol Drug Saf 16, no. 1 (January 2007): 5–16. https://doi.org/10.1002/pds.1215.
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• Cantor, Warren J., Kenneth W. Mahaffey, Zhen Huang, Pranab Das, Dietrich C. Gulba, Stanislav Glezer, Richard Gallo, et al. “Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal.” Catheter Cardiovasc Interv 69, no. 1 (January 2007): 73–83. https://doi.org/10.1002/ccd.20897.
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• Reed, S. D., R. M. Califf, and K. A. Schulman. “Is there a price to pay for short-term savings in the clinical development of new pharmaceutical products?” Drug Information Journal 41, no. 4 (January 1, 2007): 491–99. https://doi.org/10.1177/009286150704100407.
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• Harrington, Robert A., and Robert M. Califf. “Late ischemic events after clopidogrel cessation following drug-eluting stenting: should we be worried?” J Am Coll Cardiol 48, no. 12 (December 19, 2006): 2592–95. https://doi.org/10.1016/j.jacc.2006.10.025.
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• Echols, Melvin R., G Michael Felker, Kevin L. Thomas, Karen S. Pieper, Jyotsna Garg, Michael S. Cuffe, Mihai Gheorghiade, Robert M. Califf, and Christopher M. O’Connor. “Racial differences in the characteristics of patients admitted for acute decompensated heart failure and their relation to outcomes: results from the OPTIME-CHF trial.” J Card Fail 12, no. 9 (December 2006): 684–88. https://doi.org/10.1016/j.cardfail.2006.08.003.
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• Westerhout, Cynthia M., Adrián V. Hernández, Ewout W. Steyerberg, Héctor Bueno, Harvey White, Pierre Théroux, David J. Moliterno, et al. “Predictors of stroke within 30 days in patients with non-ST-segment elevation acute coronary syndromes.” Eur Heart J 27, no. 24 (December 2006): 2956–61. https://doi.org/10.1093/eurheartj/ehl356.
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• White, Harvey D., Neal S. Kleiman, Kenneth W. Mahaffey, Yuliya Lokhnygina, Karen S. Pieper, Karen Chiswell, Marc Cohen, et al. “Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial.” Am Heart J 152, no. 6 (December 2006): 1042–50. https://doi.org/10.1016/j.ahj.2006.08.002.
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• Mehta, Rajendra H., Matthew T. Roe, Anita Y. Chen, Barbara L. Lytle, Charles V. Pollack, Ralph G. Brindis, Sidney C. Smith, et al. “Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative.” Arch Intern Med 166, no. 18 (October 9, 2006): 2027–34. https://doi.org/10.1001/archinte.166.18.2027.
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• Cohen, Marc, Kenneth W. Mahaffey, Karen Pieper, Charles V. Pollack, Elliott M. Antman, James Hoekstra, Shaun G. Goodman, et al. “A subgroup analysis of the impact of prerandomization antithrombin therapy on outcomes in the SYNERGY trial: enoxaparin versus unfractionated heparin in non-ST-segment elevation acute coronary syndromes.” J Am Coll Cardiol 48, no. 7 (October 3, 2006): 1346–54. https://doi.org/10.1016/j.jacc.2006.05.058.
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• Køber, Lars, Karl Swedberg, John J. V. McMurray, Marc A. Pfeffer, Eric J. Velazquez, Rafael Diaz, Aldo P. Maggioni, et al. “Previously known and newly diagnosed atrial fibrillation: a major risk indicator after a myocardial infarction complicated by heart failure or left ventricular dysfunction.” Eur J Heart Fail 8, no. 6 (October 2006): 591–98. https://doi.org/10.1016/j.ejheart.2005.11.007.
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• Smith, Peter K., Robert M. Califf, Robert H. Tuttle, Linda K. Shaw, Kerry L. Lee, Elizabeth R. Delong, R Eric Lilly, Michael H. Sketch, Eric D. Peterson, and Robert H. Jones. “Selection of surgical or percutaneous coronary intervention provides differential longevity benefit.” Ann Thorac Surg 82, no. 4 (October 2006): 1420–28. https://doi.org/10.1016/j.athoracsur.2006.04.044.
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• James, Stefan K., Johan Lindbäck, Johanna Tilly, Agneta Siegbahn, Per Venge, Paul Armstrong, Robert Califf, Maarten L. Simoons, Lars Wallentin, and Bertil Lindahl. “Troponin-T and N-terminal pro-B-type natriuretic peptide predict mortality benefit from coronary revascularization in acute coronary syndromes: a GUSTO-IV substudy.” J Am Coll Cardiol 48, no. 6 (September 19, 2006): 1146–54. https://doi.org/10.1016/j.jacc.2006.05.056.
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• Lemos, James A. de, Stephen D. Wiviott, Sabina A. Murphy, Michael A. Blazing, Eldrin F. Lewis, Robert M. Califf, Marc A. Pfeffer, and Eugene Braunwald. “Evaluation of the National Cholesterol Education Program Adult Treatment Panel III algorithm for selecting candidates for statin therapy: insights from the A to Z trial.” Am J Cardiol 98, no. 6 (September 15, 2006): 739–42. https://doi.org/10.1016/j.amjcard.2006.03.060.
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• Benjamin, Daniel K., Philip Brian Smith, M Dianne Murphy, Rosemary Roberts, Lisa Mathis, Debbie Avant, Robert M. Califf, and Jennifer S. Li. “Peer-reviewed publication of clinical trials completed for pediatric exclusivity.” Jama 296, no. 10 (September 13, 2006): 1266–73. https://doi.org/10.1001/jama.296.10.1266.
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• Westerhout, Cynthia M., Yuling Fu, Michael S. Lauer, Stefan James, Paul W. Armstrong, Eyad Al-Hattab, Robert M. Califf, et al. “Short- and long-term risk stratification in acute coronary syndromes: the added value of quantitative ST-segment depression and multiple biomarkers.” J Am Coll Cardiol 48, no. 5 (September 5, 2006): 939–47. https://doi.org/10.1016/j.jacc.2006.04.085.
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• Califf, R. M. “Keynote: Translating clinical trials into practice.” Texas Heart Institute Journal 33, no. 2 (September 4, 2006): 192–96.
• Davidson, Karina W., David J. Kupfer, J Thomas Bigger, Robert M. Califf, Robert M. Carney, James C. Coyne, Susan M. Czajkowski, et al. “Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group Report.” Psychosom Med 68, no. 5 (September 2006): 645–50. https://doi.org/10.1097/01.psy.0000233233.48738.22.
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• Grandis, Jennifer R., James F. Battey, Robert M. Califf, Richard A. Chole, Bruce J. Gantz, George A. Gates, Lester Gorelic, et al. “Research education and training in otolaryngology: meeting summary and research opportunities.” Otolaryngology  Head and Neck Surgery : Official Journal of American Academy of Otolaryngology Head and Neck Surgery 135, no. 3 (September 2006): 361–67. https://doi.org/10.1016/j.otohns.2006.05.014.
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• Reed, Shelby D., John J. V. McMurray, Eric J. Velazquez, Kevin A. Schulman, Robert M. Califf, Lars Kober, Aldo P. Maggioni, et al. “Geographic variation in the treatment of acute myocardial infarction in the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial.” Am Heart J 152, no. 3 (September 2006): 500–508. https://doi.org/10.1016/j.ahj.2006.02.032.
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• Reed, Shelby D., Robert M. Califf, and Kevin A. Schulman. “How changes in drug-safety regulations affect the way drug and biotech companies invest in innovation.” Health Aff (Millwood) 25, no. 5 (September 2006): 1309–17. https://doi.org/10.1377/hlthaff.25.5.1309.
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• Goodman, Shaun G., Yuling Fu, Anatoly Langer, Aiala Barr, Mary Tan, Galen S. Wagner, Alejandro Barbagelata, et al. “The prognostic value of the admission and predischarge electrocardiogram in acute coronary syndromes: the GUSTO-IIb ECG Core Laboratory experience.” Am Heart J 152, no. 2 (August 2006): 277–84. https://doi.org/10.1016/j.ahj.2005.12.022.
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• Menon, Sharad, Katherine Y. Berezny, Rakhi Kilaru, Daniel K. Benjamin, Joseph D. Kay, Lydie Hazan, Ronald Portman, et al. “Racial differences are seen in blood pressure response to fosinopril in hypertensive children.” Am Heart J 152, no. 2 (August 2006): 394–99. https://doi.org/10.1016/j.ahj.2005.12.025.
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• Newby, L. K., N. M. Allen-LaPointe, A. Y. Chen, J. M. Kramer, B. G. Hammill, E. R. DeLong, L. H. Muhlbaier, and R. M. Califf. “Response to letter regarding article, "Long-term adherence to evidence-based secondary prevention therapies in coronary artery disease" [2].” Circulation 114, no. 6 (August 1, 2006). https://doi.org/10.1161/CIRCULATIONAHA.106.627521.
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• Whellan, David J., Robert H. Tuttle, Eric J. Velazquez, Linda K. Shaw, James G. Jollis, Wendell Ellis, Christopher M. O’Connor, Robert M. Califf, and Salvador Borges-Neto. “Predicting significant coronary artery disease in patients with left ventricular dysfunction.” Am Heart J 152, no. 2 (August 2006): 340–47. https://doi.org/10.1016/j.ahj.2005.12.001.
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• Morrow, David A., James A. de Lemos, Marc S. Sabatine, Stephen D. Wiviott, Michael A. Blazing, Amy Shui, Nader Rifai, Robert M. Califf, and Eugene Braunwald. “Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial.” Circulation 114, no. 4 (July 25, 2006): 281–88. https://doi.org/10.1161/CIRCULATIONAHA.106.628909.
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• Mehta, Rajendra H., Emily Honeycutt, Eric D. Peterson, Christopher B. Granger, Abdul R. Halabi, Linda K. Shaw, Peter K. Smith, Robert M. Califf, Robert A. Harrington, and Michael H. Sketch. “Impact of internal mammary artery conduit on long-term outcomes after percutaneous intervention of saphenous vein graft.” Circulation 114, no. 1 Suppl (July 4, 2006): I396–401. https://doi.org/10.1161/CIRCULATIONAHA.105.000349.
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• Alexander, Karen P., Laura Kristin Newby, Manju V. Bhapkar, Harvey D. White, Judith S. Hochman, Matthias E. Pfisterer, David J. Moliterno, et al. “International variation in invasive care of the elderly with acute coronary syndromes.” Eur Heart J 27, no. 13 (July 2006): 1558–64. https://doi.org/10.1093/eurheartj/ehl067.
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• Califf, Robert M., and Robert M. Workshop Participants. “Evaluation of diagnostic imaging technologies and therapeutics devices: better information for better decisions: proceedings of a multidisciplinary workshop.” Am Heart J 152, no. 1 (July 2006): 50–58. https://doi.org/10.1016/j.ahj.2005.10.001.
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• Janardhanan, Rajesh, Satish Kenchaiah, Eric J. Velazquez, Yuhyun Park, John J. V. McMurray, W Douglas Weaver, Peter V. Finn, et al. “Extent of coronary artery disease as a predictor of outcomes in acute myocardial infarction complicated by heart failure, left ventricular dysfunction, or both.” Am Heart J 152, no. 1 (July 2006): 183–89. https://doi.org/10.1016/j.ahj.2005.11.013.
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• Bushnell, Cheryl D., Jeffrey Griffin, L Kristin Newby, Larry B. Goldstein, Kenneth W. Mahaffey, Carmelo A. Graffagnino, Robert A. Harrington, et al. “Statin use and sex-specific stroke outcomes in patients with vascular disease.” Stroke 37, no. 6 (June 2006): 1427–31. https://doi.org/10.1161/01.STR.0000221315.60282.ca.
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• Roe, Matthew T., Eric D. Peterson, L Kristin Newby, Anita Y. Chen, Charles V. Pollack, Ralph G. Brindis, Robert A. Harrington, et al. “The influence of risk status on guideline adherence for patients with non-ST-segment elevation acute coronary syndromes.” Am Heart J 151, no. 6 (June 2006): 1205–13. https://doi.org/10.1016/j.ahj.2005.08.006.
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• Allen LaPointe, N. M., E. R. DeLong, A. Chen, B. G. Hammill, L. H. Muhlbaier, R. M. Califf, and J. M. Kramer. “Multifaceted intervention to promote β-blocker use in heart failure.” American Heart Journal 151, no. 5 (May 1, 2006): 999–1005. https://doi.org/10.1016/j.ahj.2005.10.011.
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• Kaul, Padma, Wei-Ching Chang, A Michael Lincoff, Philip Aylward, Amadeo Betriu, Christoph Bode, Robert M. Califf, et al. “Optimizing use of revascularization and clinical outcomes in ST-elevation myocardial infarction: insights from the GUSTO-V trial.” Eur Heart J 27, no. 10 (May 2006): 1198–1206. https://doi.org/10.1093/eurheartj/ehi854.
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• LaPointe, Nancy M Allen, Elizabeth R. DeLong, Anita Chen, Bradley G. Hammill, Lawrence H. Muhlbaier, Robert M. Califf, and Judith M. Kramer. “Multifaceted intervention to promote beta-blocker use in heart failure.” Am Heart J 151, no. 5 (May 2006): 992–98. https://doi.org/10.1016/j.ahj.2005.06.038.
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• O’Shea, J Conor, and Robert M. Califf. “24-hour ambulatory blood pressure monitoring.” Am Heart J 151, no. 5 (May 2006): 962–68. https://doi.org/10.1016/j.ahj.2005.03.020.
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• Begg, Colin B., Otis Brawley, Robert M. Califf, David L. Demets, Susan S. Ellenberg, and Richard S. Kaplan. “Marketing drugs too early in testing.” Science 312, no. 5771 (April 14, 2006): 195. https://doi.org/10.1126/science.312.5771.195c.
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• Califf, Robert M. “Fondaparinux in ST-segment elevation myocardial infarction: the drug, the strategy, the environment, or all of the above?” Jama 295, no. 13 (April 5, 2006): 1579–80. https://doi.org/10.1001/jama.295.13.jed60020.
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• Wiviott, Stephen D., James A. de Lemos, Christopher P. Cannon, Michael Blazing, Sabina A. Murphy, Carolyn H. McCabe, Robert Califf, and Eugene Braunwald. “A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22.” Circulation 113, no. 11 (March 21, 2006): 1406–14. https://doi.org/10.1161/CIRCULATIONAHA.105.586347.
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• Stevenson, L. W., C. M. O’Connor, and R. M. Califf. “In reply [2].” Journal of the American Medical Association 295, no. 10 (March 8, 2006): 1121–22. https://doi.org/10.1001/jama.295.10.1121-b.
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• Orlandini, Andrés, Rafael Díaz, Daniel Wojdyla, Karen Pieper, Frans Van de Werf, Christopher B. Granger, Robert A. Harrington, et al. “Outcomes of patients in clinical trials with ST-segment elevation myocardial infarction among countries with different gross national incomes.” Eur Heart J 27, no. 5 (March 2006): 527–33. https://doi.org/10.1093/eurheartj/ehi701.
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• Patel, Manesh R., Mark Donahue, Peter W. F. Wilson, and Robert M. Califf. “Clinical trial issues in weight-loss therapy.” Am Heart J 151, no. 3 (March 2006): 633–42. https://doi.org/10.1016/j.ahj.2005.03.006.
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• McMurray, John, Scott Solomon, Karen Pieper, Shelby Reed, Jean Rouleau, Eric Velazquez, Harvey White, et al. “The effect of valsartan, captopril, or both on atherosclerotic events after acute myocardial infarction: an analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT).” J Am Coll Cardiol 47, no. 4 (February 21, 2006): 726–33. https://doi.org/10.1016/j.jacc.2005.09.055.
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• Rao, Sunil V., Kristi O’Grady, Karen S. Pieper, Christopher B. Granger, L Kristin Newby, Kenneth W. Mahaffey, David J. Moliterno, et al. “A comparison of the clinical impact of bleeding measured by two different classifications among patients with acute coronary syndromes.” J Am Coll Cardiol 47, no. 4 (February 21, 2006): 809–16. https://doi.org/10.1016/j.jacc.2005.09.060.
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• Patel, Manesh R., Trip J. Meine, Lauren Lindblad, Jeffrey Griffin, Christopher B. Granger, Richard C. Becker, Frans Van de Werf, Harvey White, Robert M. Califf, and Robert A. Harrington. “Cardiac tamponade in the fibrinolytic era: analysis of >100,000 patients with ST-segment elevation myocardial infarction.” Am Heart J 151, no. 2 (February 2006): 316–22. https://doi.org/10.1016/j.ahj.2005.04.014.
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• Newby, L Kristin, Nancy M Allen LaPointe, Anita Y. Chen, Judith M. Kramer, Bradley G. Hammill, Elizabeth R. DeLong, Lawrence H. Muhlbaier, and Robert M. Califf. “Long-term adherence to evidence-based secondary prevention therapies in coronary artery disease.” Circulation 113, no. 2 (January 17, 2006): 203–12. https://doi.org/10.1161/CIRCULATIONAHA.105.505636.
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• James, Stefan K., Bertil Lindahl, Jorik R. Timmer, Jan Paul Ottervanger, Agneta Siegbahn, Mats Stridsberg, Paul Armstrong, Robert Califf, Lars Wallentin, and Maarten L. Simoons. “Usefulness of biomarkers for predicting long-term mortality in patients with diabetes mellitus and non-ST-elevation acute coronary syndromes (a GUSTO IV substudy).” Am J Cardiol 97, no. 2 (January 15, 2006): 167–72. https://doi.org/10.1016/j.amjcard.2005.08.036.
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• Califf, Robert M. “Translating clinical trials into practice.” Tex Heart Inst J 33, no. 2 (2006): 192–96.
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• Califf, Robert M. “Clinical trials bureaucracy: unintended consequences of well-intentioned policy.” Clin Trials 3, no. 6 (2006): 496–502. https://doi.org/10.1177/1740774506073173.
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• Galla, John M., Kenneth W. Mahaffey, Shelly K. Sapp, John H. Alexander, Matthew T. Roe, E Magnus Ohman, Christopher B. Granger, et al. “Elevated creatine kinase-MB with normal creatine kinase predicts worse outcomes in patients with acute coronary syndromes: results from 4 large clinical trials.” Am Heart J 151, no. 1 (January 2006): 16–24. https://doi.org/10.1016/j.ahj.2005.01.045.
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• Heitner, John, Mat Lotfi, J Kevin Harrison, Christopher Cabell, Igor Klem, Lesan Banko, Raymond J. Kim, and Robert M. Califf. “Where's the flap?” Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 8, no. 3 (January 2006): 549–50. https://doi.org/10.1080/10976640600584785.
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• Kauf, Teresa L., Eric J. Velazquez, David R. Crosslin, W Douglas Weaver, Rafael Diaz, Christopher B. Granger, John J. V. McMurray, et al. “The cost of acute myocardial infarction in the new millennium: evidence from a multinational registry.” Am Heart J 151, no. 1 (January 2006): 206–12. https://doi.org/10.1016/j.ahj.2005.02.028.
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• McMurray, J. J. V., R. M. Califf, and M. A. Pfeffer. “Reply.” Journal of the American College of Cardiology 48, no. 7 (2006): 1471-. https://doi.org/10.1016/j.jacc.2006.07.012.
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• Mehta, Rajendra H., David Marks, Robert M. Califf, SeeHyang Sohn, Karen S. Pieper, Frans Van de Werf, Eric D. Peterson, et al. “Differences in the clinical features and outcomes in African Americans and whites with myocardial infarction.” Am J Med 119, no. 1 (January 2006): 70.e1-70.e8. https://doi.org/10.1016/j.amjmed.2005.07.043.
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• Morrow, David A., James A. de Lemos, Michael A. Blazing, Marc S. Sabatine, Sabina A. Murphy, Petr Jarolim, Harvey D. White, et al. “Prognostic value of serial B-type natriuretic peptide testing during follow-up of patients with unstable coronary artery disease.” Jama 294, no. 22 (December 14, 2005): 2866–71. https://doi.org/10.1001/jama.294.22.2866.
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• White, Harvey D., Philip E. G. Aylward, Zhen Huang, Anthony J. Dalby, W Douglas Weaver, Ståle Barvik, José Antonio Marin-Neto, et al. “Mortality and morbidity remain high despite captopril and/or Valsartan therapy in elderly patients with left ventricular systolic dysfunction, heart failure, or both after acute myocardial infarction: results from the Valsartan in Acute Myocardial Infarction Trial (VALIANT).” Circulation 112, no. 22 (November 29, 2005): 3391–99. https://doi.org/10.1161/CIRCULATIONAHA.105.551143.
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• Mahaffey, Kenneth W., Marc Cohen, Jyotsna Garg, Elliott Antman, Neal S. Kleiman, Shaun G. Goodman, Lisa G. Berdan, et al. “High-risk patients with acute coronary syndromes treated with low-molecular-weight or unfractionated heparin: outcomes at 6 months and 1 year in the SYNERGY trial.” Jama 294, no. 20 (November 23, 2005): 2594–2600. https://doi.org/10.1001/jama.294.20.2594.
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• Alexander, John H., Gail Hafley, Robert A. Harrington, Eric D. Peterson, T Bruce Ferguson, Todd J. Lorenz, Abhinav Goyal, et al. “Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial.” Jama 294, no. 19 (November 16, 2005): 2446–54. https://doi.org/10.1001/jama.294.19.2446.
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• Rao, Sunil V., Kristi O’Grady, Karen S. Pieper, Christopher B. Granger, L Kristin Newby, Frans Van de Werf, Kenneth W. Mahaffey, Robert M. Califf, and Robert A. Harrington. “Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes.” Am J Cardiol 96, no. 9 (November 1, 2005): 1200–1206. https://doi.org/10.1016/j.amjcard.2005.06.056.
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• Shah, Monica R., Karen A. Claise, Margaret T. Bowers, Manjushri Bhapkar, Julie Little, Anju Nohria, Laura H. Gaulden, et al. “Testing new targets of therapy in advanced heart failure: the design and rationale of the Strategies for Tailoring Advanced Heart Failure Regimens in the Outpatient Setting: BRain NatrIuretic Peptide Versus the Clinical CongesTion ScorE (STARBRITE) trial.” Am Heart J 150, no. 5 (November 2005): 893–98. https://doi.org/10.1016/j.ahj.2005.01.003.
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• McMahon, Timothy J., Gregory S. Ahearn, Martin P. Moya, Andrew J. Gow, Yuh-Chin T. Huang, Benjamin P. Luchsinger, Raphael Nudelman, et al. “A nitric oxide processing defect of red blood cells created by hypoxia: deficiency of S-nitrosohemoglobin in pulmonary hypertension.” Proc Natl Acad Sci U S A 102, no. 41 (October 11, 2005): 14801–6. https://doi.org/10.1073/pnas.0506957102.
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• Hernandez, Adrian F., Eric J. Velazquez, Scott D. Solomon, Rakhi Kilaru, Rafael Diaz, Christopher M. O’Connor, George Ertl, et al. “Left ventricular assessment in myocardial infarction: the VALIANT registry.” Arch Intern Med 165, no. 18 (October 10, 2005): 2162–69. https://doi.org/10.1001/archinte.165.18.2162.
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• Binanay, Cynthia, Robert M. Califf, Vic Hasselblad, Christopher M. O’Connor, Monica R. Shah, George Sopko, Lynne W. Stevenson, et al. “Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial.” Jama 294, no. 13 (October 5, 2005): 1625–33. https://doi.org/10.1001/jama.294.13.1625.
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• Shah, Monica R., Vic Hasselblad, Lynne W. Stevenson, Cynthia Binanay, Christopher M. O’Connor, George Sopko, and Robert M. Califf. “Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials.” Jama 294, no. 13 (October 5, 2005): 1664–70. https://doi.org/10.1001/jama.294.13.1664.
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• Alexander, John H., T Bruce Ferguson, Diane M. Joseph, Michael J. Mack, Randall K. Wolf, C Michael Gibson, Daniel Gennevois, et al. “The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristics.” Am Heart J 150, no. 4 (October 2005): 643–49. https://doi.org/10.1016/j.ahj.2005.05.021.
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• Barbagelata, Alejandro, Marcelo F. Di Carli, Robert M. Califf, Jyotsna Garg, Yochai Birnbaum, Liliana Grinfeld, Raymond J. Gibbons, et al. “Electrocardiographic infarct size assessment after thrombolysis: insights from the Acute Myocardial Infarction STudy ADenosine (AMISTAD) trial.” Am Heart J 150, no. 4 (October 2005): 659–65. https://doi.org/10.1016/j.ahj.2004.10.014.
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• Reddan, Donal N., Lynda Szczech, Manjushri V. Bhapkar, David J. Moliterno, Robert M. Califf, E Magnus Ohman, Peter B. Berger, et al. “Renal function, concomitant medication use and outcomes following acute coronary syndromes.” Nephrol Dial Transplant 20, no. 10 (October 2005): 2105–12. https://doi.org/10.1093/ndt/gfh981.
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• Savonitto, Stefano, Mauricio G. Cohen, Alessandro Politi, Michael P. Hudson, David F. Kong, Yao Huang, Karen S. Pieper, et al. “Extent of ST-segment depression and cardiac events in non-ST-segment elevation acute coronary syndromes.” Eur Heart J 26, no. 20 (October 2005): 2106–13. https://doi.org/10.1093/eurheartj/ehi395.
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• Szummer, Karolina E., Scott D. Solomon, Eric J. Velazquez, Rakhi Kilaru, John McMurray, Jean-Lucien Rouleau, Kenneth W. Mahaffey, et al. “Heart failure on admission and the risk of stroke following acute myocardial infarction: the VALIANT registry.” Eur Heart J 26, no. 20 (October 2005): 2114–19. https://doi.org/10.1093/eurheartj/ehi352.
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• Khera, Amit, and Benjamin D. Levine. “Sudden death in patients with myocardial infarction.” N Engl J Med 353, no. 12 (September 22, 2005): 1294–97.
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• Eisenstein, Eric L., Darren K. McGuire, Manjushri V. Bhapkar, Arni Kristinsson, Judith S. Hochman, David F. Kong, Robert M. Califf, Frans Van de Werf, William S. Yancy, and L Kristin Newby. “Elevated body mass index and intermediate-term clinical outcomes after acute coronary syndromes.” Am J Med 118, no. 9 (September 2005): 981–90. https://doi.org/10.1016/j.amjmed.2005.02.017.
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• Califf, Robert M. “Stenting or surgery: an opportunity to do it right.” J Am Coll Cardiol 46, no. 4 (August 16, 2005): 589–91. https://doi.org/10.1016/j.jacc.2005.05.024.
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• Reed, Shelby D., Jasmina I. Radeva, Kevin P. Weinfurt, John J. V. McMurray, Marc A. Pfeffer, Eric J. Velazquez, Jennifer S. Allsbrook, et al. “Resource use, costs, and quality of life among patients in the multinational Valsartan in Acute Myocardial Infarction Trial (VALIANT).” Am Heart J 150, no. 2 (August 2005): 323–29. https://doi.org/10.1016/j.ahj.2004.08.037.
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• Wong, Cheuk-Kit, John K. French, Philip E. G. Aylward, Ralph A. H. Stewart, Wanzhen Gao, Paul W. Armstrong, Frans J. J. Van De Werf, et al. “Patients with prolonged ischemic chest pain and presumed-new left bundle branch block have heterogeneous outcomes depending on the presence of ST-segment changes.” J Am Coll Cardiol 46, no. 1 (July 5, 2005): 29–38. https://doi.org/10.1016/j.jacc.2005.02.084.
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• Jiang, Wei, Alexander Glassman, Ranga Krishnan, Christopher M. O’Connor, and Robert M. Califf. “Depression and ischemic heart disease: what have we learned so far and what must we do in the future?” Am Heart J 150, no. 1 (July 2005): 54–78. https://doi.org/10.1016/j.ahj.2005.04.012.
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• Solomon, Scott D., Hicham Skali, Nagesh S. Anavekar, Mikhail Bourgoun, Stale Barvik, Jalal K. Ghali, J Wayne Warnica, et al. “Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction.” Circulation 111, no. 25 (June 28, 2005): 3411–19. https://doi.org/10.1161/CIRCULATIONAHA.104.508093.
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• Solomon, Scott D., Steve Zelenkofske, John J. V. McMurray, Peter V. Finn, Eric Velazquez, George Ertl, Adam Harsanyi, et al. “Sudden death in patients with myocardial infarction and left ventricular dysfunction, heart failure, or both.” N Engl J Med 352, no. 25 (June 23, 2005): 2581–88. https://doi.org/10.1056/NEJMoa043938.
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• Al-Khatib, Sana M., Gillian D. Sanders, Daniel B. Mark, Kerry L. Lee, Gust H. Bardy, J Thomas Bigger, Alfred E. Buxton, et al. “Implantable cardioverter defibrillators and cardiac resynchronization therapy in patients with left ventricular dysfunction: randomized trial evidence through 2004.” Am Heart J 149, no. 6 (June 2005): 1020–34. https://doi.org/10.1016/j.ahj.2005.02.005.
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• Giugliano, Robert P., L Kristin Newby, Robert A. Harrington, C Michael Gibson, Frans Van de Werf, Paul Armstrong, Gilles Montalescot, et al. “The early glycoprotein IIb/IIIa inhibition in non-ST-segment elevation acute coronary syndrome (EARLY ACS) trial: a randomized placebo-controlled trial evaluating the clinical benefits of early front-loaded eptifibatide in the treatment of patients with non-ST-segment elevation acute coronary syndrome--study design and rationale.” Am Heart J 149, no. 6 (June 2005): 994–1002. https://doi.org/10.1016/j.ahj.2005.03.029.
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• Mehta, Rajendra H., Robert M. Califf, Jyotsna Garg, Karen S. Pieper, John H. Alexander, David J. Moliterno, Frans Van de Werf, et al. “Association of height with outcomes in patients with acute myocardial infarction receiving reperfusion therapy.” Am J Cardiol 95, no. 11 (June 1, 2005): 1371–75. https://doi.org/10.1016/j.amjcard.2005.01.087.
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• Klein, Liviu, Christopher M. O’Connor, Jeffrey D. Leimberger, Wendy Gattis-Stough, Ileana L. Piña, G Michael Felker, Kirkwood F. Adams, Robert M. Califf, Mihai Gheorghiade, and Mihai OPTIME-CHF Investigators. “Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study.” Circulation 111, no. 19 (May 17, 2005): 2454–60. https://doi.org/10.1161/01.CIR.0000165065.82609.3D.
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• Al-Khatib, Sana M., Nancy M. Allen LaPointe, Judith M. Kramer, Anita Y. Chen, Bradley G. Hammill, Liz Delong, and Robert M. Califf. “A survey of health care practitioners' knowledge of the QT interval.” J Gen Intern Med 20, no. 5 (May 2005): 392–96. https://doi.org/10.1111/j.1525-1497.2005.0101.x.
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• Califf, R. M., and T. F. Griffith. “Results of expert meetings. Uncontrolled systolic hypertension Washington, DC, April 25-27, 2002.” American Heart Journal 149, no. 5 (May 1, 2005): 768. https://doi.org/10.1016/j.ahj.2005.01.036.
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• Cohen, Mauricio G., Robert V. Kelly, David F. Kong, Venu Menon, Monica Shah, Jorge Ferreira, Karen S. Pieper, et al. “Pulmonary artery catheterization in acute coronary syndromes: insights from the GUSTO IIb and GUSTO III trials.” Am J Med 118, no. 5 (May 2005): 482–88. https://doi.org/10.1016/j.amjmed.2004.12.018.
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• March, John S., Susan G. Silva, Scott Compton, Mark Shapiro, Robert Califf, and Ranga Krishnan. “The case for practical clinical trials in psychiatry.” Am J Psychiatry 162, no. 5 (May 2005): 836–46. https://doi.org/10.1176/appi.ajp.162.5.836.
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• Al-Khatib, Sana M., Kevin J. Anstrom, Eric L. Eisenstein, Eric D. Peterson, James G. Jollis, Daniel B. Mark, Yun Li, Christopher M. O’Connor, Linda K. Shaw, and Robert M. Califf. “Clinical and economic implications of the Multicenter Automatic Defibrillator Implantation Trial-II.” Ann Intern Med 142, no. 8 (April 19, 2005): 593–600. https://doi.org/10.7326/0003-4819-142-8-200504190-00007.
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• Mehta, Rajendra H., John H. Alexander, Frans Van de Werf, Paul W. Armstrong, Karen S. Pieper, Jyotsna Garg, Robert M. Califf, and Christopher B. Granger. “Relationship of incorrect dosing of fibrinolytic therapy and clinical outcomes.” Jama 293, no. 14 (April 13, 2005): 1746–50. https://doi.org/10.1001/jama.293.14.1746.
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• Califf, Robert M., John L. Petersen, Vic Hasselblad, Kenneth W. Mahaffey, and James J. Ferguson. “A perspective on trials comparing enoxaparin and unfractionated heparin in the treatment of non-ST-elevation acute coronary syndromes.” Am Heart J 149, no. 4 Suppl (April 2005): S91–99. https://doi.org/10.1016/j.ahj.2005.02.021.
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• Meine, Trip J., Sana M. Al-Khatib, John H. Alexander, Christopher B. Granger, Harvey D. White, Rakhi Kilaru, Kathryn Williams, E Magnus Ohman, Eric Topol, and Robert M. Califf. “Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy.” Am Heart J 149, no. 4 (April 2005): 670–74. https://doi.org/10.1016/j.ahj.2004.07.035.
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• Drew, Barbara J., Robert M. Califf, Marjorie Funk, Elizabeth S. Kaufman, Mitchell W. Krucoff, Michael M. Laks, Peter W. Macfarlane, et al. “AHA scientific statement: practice standards for electrocardiographic monitoring in hospital settings: an American Heart Association Scientific Statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: endorsed by the International Society of Computerized electrocardiology and the American Association of Critical-Care Nurses.” J Cardiovasc Nurs 20, no. 2 (March 2005): 76–106. https://doi.org/10.1097/00005082-200503000-00003.
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• Eisenstein, Eric L., Philip W. Lemons, Barbara E. Tardiff, Kevin A. Schulman, M King Jolly, and Robert M. Califf. “Reducing the costs of phase III cardiovascular clinical trials.” Am Heart J 149, no. 3 (March 2005): 482–88. https://doi.org/10.1016/j.ahj.2004.04.049.
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• Muni, Neal I., Robert M. Califf, Jonette R. Foy, Ashley B. Boam, Bram D. Zuckerman, and Richard E. Kuntz. “Coronary drug-eluting stent development: issues in trial design.” Am Heart J 149, no. 3 (March 2005): 415–33. https://doi.org/10.1016/j.ahj.2004.09.001.
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• Rebeiz, Abdallah G., Per Johanson, Cindy L. Green, Suzanne W. Crater, Matthew T. Roe, Anatoly Langer, Robert P. Giugliano, et al. “Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials).” Am J Cardiol 95, no. 5 (March 1, 2005): 611–14. https://doi.org/10.1016/j.amjcard.2004.10.038.
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• Reed, Shelby D., Kevin J. Anstrom, Ameet Bakhai, Andrew H. Briggs, Robert M. Califf, David J. Cohen, Michael F. Drummond, et al. “Conducting economic evaluations alongside multinational clinical trials: toward a research consensus.” Am Heart J 149, no. 3 (March 2005): 434–43. https://doi.org/10.1016/j.ahj.2004.11.001.
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• Rathore, Saif S., Martha J. Radford, and Harlan M. Krumholz. “Blood transfusion in patients with acute coronary syndrome.” Jama 293, no. 6 (February 9, 2005): 673. https://doi.org/10.1001/jama.293.6.673-a.
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• Califf, Robert M. “Simple principles of clinical trials remain powerful.” Jama 293, no. 4 (January 26, 2005): 489–91. https://doi.org/10.1001/jama.293.4.489.
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• Borges-Neto, Salvador, Linda K. Shaw, Robert H. Tuttle, John H. Alexander, William T. Smith, Marianna Chambless, R Edward Coleman, Robert A. Harrington, and Robert M. Califf. “Incremental prognostic power of single-photon emission computed tomographic myocardial perfusion imaging in patients with known or suspected coronary artery disease.” Am J Cardiol 95, no. 2 (January 15, 2005): 182–88. https://doi.org/10.1016/j.amjcard.2004.09.004.
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• Crouse, John R. “High-dose statins in acute coronary syndromes.” Jama 293, no. 1 (January 5, 2005): 36. https://doi.org/10.1001/jama.293.1.36-a.
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• Kupersmith, J., N. Sung, M. Genel, H. Slavkin, R. Califf, R. Bonow, L. Sherwood, et al. “Creating a new structure for research on health care effectiveness.” Journal of Investigative Medicine 53, no. 2 (2005): 67–72.
• Labinaz, Marino, Jasmine Mathias, Karen Pieper, Christopher B. Granger, A Michael Lincoff, David J. Moliterno, Frans Van de Werf, et al. “Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: a pooled analysis of three randomized clinical trials.” Eur Heart J 26, no. 2 (January 2005): 128–36. https://doi.org/10.1093/eurheartj/ehi061.
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• Miranda, Phillippa J., Ralph A. DeFronzo, Robert M. Califf, and John R. Guyton. “Metabolic syndrome: definition, pathophysiology, and mechanisms.” Am Heart J 149, no. 1 (January 2005): 33–45. https://doi.org/10.1016/j.ahj.2004.07.013.
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• Miranda, Phillippa J., Ralph A. DeFronzo, Robert M. Califf, and John R. Guyton. “Metabolic syndrome: evaluation of pathological and therapeutic outcomes.” Am Heart J 149, no. 1 (January 2005): 20–32. https://doi.org/10.1016/j.ahj.2004.07.012.
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• Armstrong, Paul W., L Kristin Newby, Christopher B. Granger, Kerry L. Lee, R John Simes, Frans Van de Werf, Harvey D. White, Robert M. Califf, and Robert M. Virtual Coordinating Centre for Global Collaborative Cardiovascular Research (VIGOUR) Group. “Lessons learned from a clinical trial.” Circulation 110, no. 23 (December 7, 2004): 3610–14. https://doi.org/10.1161/01.CIR.0000148680.83392.50.
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• Felker, G Michael, Jeffrey D. Leimberger, Robert M. Califf, Michael S. Cuffe, Barry M. Massie, Kirkwood F. Adams, Mihai Gheorghiade, and Christopher M. O’Connor. “Risk stratification after hospitalization for decompensated heart failure.” J Card Fail 10, no. 6 (December 2004): 460–66. https://doi.org/10.1016/j.cardfail.2004.02.011.
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• Mascelli, Mary Ann, Efthymios N. Deliargyris, Lakshmi V. Damaraju, Elliot S. Barnathan, Robert M. Califf, Maarten L. Simoons, and David C. Sane. “Antibodies to platelet factor 4/heparin are associated with elevated endothelial cell activation markers in patients with acute coronary ischemic syndromes.” J Thromb Thrombolysis 18, no. 3 (December 2004): 171–75. https://doi.org/10.1007/s11239-005-0342-9.
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• Jiang, Wei, Maragatha Kuchibhatla, Michael S. Cuffe, Eric J. Christopher, Jude D. Alexander, Greg L. Clary, Michael A. Blazing, et al. “Prognostic value of anxiety and depression in patients with chronic heart failure.” Circulation 110, no. 22 (November 30, 2004): 3452–56. https://doi.org/10.1161/01.CIR.0000148138.25157.F9.
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• Califf, Robert M., Thomas Ryan, Pamela Douglas, and Pascal J. Goldschmidt-Clermont. “A time of accelerated change in academic cardiovascular medicine: implications for academic divisions of cardiology and their training programs.” J Am Coll Cardiol 44, no. 10 (November 16, 2004): 1957–65. https://doi.org/10.1016/j.jacc.2004.08.046.
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• Barbagelata, Alejandro, Robert M. Califf, Elena B. Sgarbossa, David Knight, Daniel B. Mark, Christopher B. Granger, Paul W. Armstrong, et al. “Prognostic value of predischarge electrocardiographic measurement of infarct size after thrombolysis: insights from GUSTO I Economics and Quality of Life substudy.” Am Heart J 148, no. 5 (November 2004): 795–802. https://doi.org/10.1016/j.ahj.2004.04.046.
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• Califf, Robert M., and Sidney C. Smith. “Introduction. Quality of health care.” Am Heart J 148, no. 5 Suppl (November 2004): S27–28. https://doi.org/10.1016/j.ahj.2004.09.011.
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• Madan, Mina, Marino Labinaz, Eric A. Cohen, Christopher E. Buller, Warren J. Cantor, Peter Seidelin, John Ducas, et al. “A comparison of clinical outcomes between Canadian and American patients after nonurgent coronary stenting.” The Canadian Journal of Cardiology 20, no. 13 (November 2004): 1343–49.
• Velazquez, Eric J., Gary S. Francis, Paul W. Armstrong, Phillip E. Aylward, Rafael Diaz, Christopher M. O’Connor, Harvey D. White, et al. “An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry.” Eur Heart J 25, no. 21 (November 2004): 1911–19. https://doi.org/10.1016/j.ehj.2004.08.006.
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• Kanna, Balavenkatesh, and Puneeta Sharma. “Enoxaparin vs unfractionated heparin in acute coronary syndrome.” Jama 292, no. 16 (October 27, 2004): 1952. https://doi.org/10.1001/jama.292.16.1952-b.
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• Drew, Barbara J., Robert M. Califf, Marjorie Funk, Elizabeth S. Kaufman, Mitchell W. Krucoff, Michael M. Laks, Peter W. Macfarlane, et al. “Practice standards for electrocardiographic monitoring in hospital settings: an American Heart Association scientific statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: endorsed by the International Society of Computerized Electrocardiology and the American Association of Critical-Care Nurses.” Circulation 110, no. 17 (October 26, 2004): 2721–46. https://doi.org/10.1161/01.CIR.0000145144.56673.59.
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• Califf, Robert M., Steven E. Nissen, Anthony N. DeMaria, Erik Magnus Ohman, Bertram Pitt, James T. Willerson, David W. Bilheimer, et al. “Task force 2: Investigator participation in clinical research.” J Am Coll Cardiol 44, no. 8 (October 19, 2004): 1729–36. https://doi.org/10.1016/j.jacc.2004.08.039.
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• Popp, Richard J., Sidney C. Smith, Rober J. Adams, Elliot M. Antman, Rae Ellen W. Kavey, Anthony N. DeMaria, Erik Magnus Ohman, et al. “ACCF/AHA consensus conference report on professionalism and ethics.” Circulation 110, no. 16 (October 19, 2004): 2506–49. https://doi.org/10.1161/01.CIR.0000147952.60985.b0.
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• Rao, Sunil V., James G. Jollis, Robert A. Harrington, Christopher B. Granger, L Kristin Newby, Paul W. Armstrong, David J. Moliterno, et al. “Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes.” Jama 292, no. 13 (October 6, 2004): 1555–62. https://doi.org/10.1001/jama.292.13.1555.
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• Lemos, James A. de, Michael A. Blazing, Stephen D. Wiviott, William E. Brady, Harvey D. White, Keith A. A. Fox, Joanne Palmisano, et al. “Enoxaparin versus unfractionated heparin in patients treated with tirofiban, aspirin and an early conservative initial management strategy: results from the A phase of the A-to-Z trial.” Eur Heart J 25, no. 19 (October 2004): 1688–94. https://doi.org/10.1016/j.ehj.2004.06.028.
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• Parsons, Elizabeth, L Kristin Newby, Manjushri V. Bhapkar, Karen P. Alexander, Harvey D. White, Svati H. Shah, Cheryl D. Bushnell, Robert M. Califf, and Robert M. Symphony and 2nd Symphony Investigators. “Postmenopausal hormone use in women with acute coronary syndromes.” J Womens Health (Larchmt) 13, no. 8 (October 2004): 863–71. https://doi.org/10.1089/jwh.2004.13.863.
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• Kaul, Padma, Paul W. Armstrong, Wei-Ching Chang, C David Naylor, Christopher B. Granger, Kerry L. Lee, Eric D. Peterson, Robert M. Califf, Eric J. Topol, and Daniel B. Mark. “Long-term mortality of patients with acute myocardial infarction in the United States and Canada: comparison of patients enrolled in Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I.” Circulation 110, no. 13 (September 28, 2004): 1754–60. https://doi.org/10.1161/01.CIR.0000142671.06167.91.
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• Anavekar, Nagesh S., John J. V. McMurray, Eric J. Velazquez, Scott D. Solomon, Lars Kober, Jean-Lucien Rouleau, Harvey D. White, et al. “Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction.” N Engl J Med 351, no. 13 (September 23, 2004): 1285–95. https://doi.org/10.1056/NEJMoa041365.
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• Aguilar, David, Scott D. Solomon, Lars Køber, Jean-Lucien Rouleau, Hicham Skali, John J. V. McMurray, Gary S. Francis, et al. “Newly diagnosed and previously known diabetes mellitus and 1-year outcomes of acute myocardial infarction: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial.” Circulation 110, no. 12 (September 21, 2004): 1572–78. https://doi.org/10.1161/01.CIR.0000142047.28024.F2.
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• Al-Khatib, Sana M., Linda K. Shaw, Kerry L. Lee, Christopher O’Connor, and Robert M. Califf. “Is rhythm control superior to rate control in patients with atrial fibrillation and congestive heart failure?” Am J Cardiol 94, no. 6 (September 15, 2004): 797–800. https://doi.org/10.1016/j.amjcard.2004.06.009.
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• Lemos, James A. de, Michael A. Blazing, Stephen D. Wiviott, Eldrin F. Lewis, Keith A. A. Fox, Harvey D. White, Jean-Lucien Rouleau, et al. “Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial.” Jama 292, no. 11 (September 15, 2004): 1307–16. https://doi.org/10.1001/jama.292.11.1307.
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• Kassem-Moussa, Hassan, Kenneth W. Mahaffey, Carmelo Graffagnino, Gudaye Tasissa, Cathy A. Sila, R John Simes, Harvey D. White, et al. “Incidence and characteristics of stroke during 90-day follow-up in patients stabilized after an acute coronary syndrome.” Am Heart J 148, no. 3 (September 2004): 439–46. https://doi.org/10.1016/j.ahj.2004.01.028.
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• Li, Jennifer S., Katherine Berezny, Rakhi Kilaru, Lydie Hazan, Ronald Portman, Ronald Hogg, Randall D. Jenkins, et al. “Is the extrapolated adult dose of fosinopril safe and effective in treating hypertensive children?” Hypertension 44, no. 3 (September 2004): 289–93. https://doi.org/10.1161/01.HYP.0000138069.68413.f0.
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• Gibson, C Michael, Lisa K. Jennings, Sabina A. Murphy, David P. Lorenz, Robert P. Giugliano, Robert A. Harrington, Shila Cholera, et al. “Association between platelet receptor occupancy after eptifibatide (integrilin) therapy and patency, myocardial perfusion, and ST-segment resolution among patients with ST-segment-elevation myocardial infarction: an INTEGRITI (Integrilin and Tenecteplase in Acute Myocardial Infarction) substudy.” Circulation 110, no. 6 (August 10, 2004): 679–84. https://doi.org/10.1161/01.CIR.0000137912.11655.F6.
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• Best, Patricia J. M., Donal N. Reddan, Peter B. Berger, Lynda A. Szczech, Peter A. McCullough, and Robert M. Califf. “Cardiovascular disease and chronic kidney disease: insights and an update.” Am Heart J 148, no. 2 (August 2004): 230–42. https://doi.org/10.1016/j.ahj.2004.04.011.
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• McCullough, Peter A., George L. Bakris, William F. Owen, Preston S. Klassen, and Robert M. Califf. “Slowing the progression of diabetic nephropathy and its cardiovascular consequences.” Am Heart J 148, no. 2 (August 2004): 243–51. https://doi.org/10.1016/j.ahj.2004.03.042.
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• Petersen, John L., Kenneth W. Mahaffey, Richard C. Becker, Shaun G. Goodman, Neal S. Kleiman, A. J. Marian, Gregg W. Stone, et al. “Coordinated series of studies to evaluate characteristics and mechanisms of acute coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractionated heparin: design and rationale of the SYNERGY Library.” Am Heart J 148, no. 2 (August 2004): 269–76. https://doi.org/10.1016/j.ahj.2004.03.022.
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• Baughman, Kenneth Lee, Carl J. Pepine, Jonathan Abrams, Thomas M. Bashore, Robert M. Califf, Arthur M. Feldman, W Bruce Fye, et al. “Working group 1: How to increase the output of cardiologists.” J Am Coll Cardiol 44, no. 2 (July 21, 2004): 233–37. https://doi.org/10.1016/j.jacc.2004.05.020.
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• Blazing, Michael A., James A. de Lemos, Harvey D. White, Keith A. A. Fox, Freek W. A. Verheugt, Diego Ardissino, Peter M. DiBattiste, et al. “Safety and efficacy of enoxaparin vs unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who receive tirofiban and aspirin: a randomized controlled trial.” Jama 292, no. 1 (July 7, 2004): 55–64. https://doi.org/10.1001/jama.292.1.55.
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• Ferguson, James J., Robert M. Califf, Elliott M. Antman, Marc Cohen, Cindy L. Grines, Shaun Goodman, Dean J. Kereiakes, et al. “Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial.” Jama 292, no. 1 (July 7, 2004): 45–54. https://doi.org/10.1001/jama.292.1.45.
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• Petersen, John L., Kenneth W. Mahaffey, Vic Hasselblad, Elliott M. Antman, Marc Cohen, Shaun G. Goodman, Anatoly Langer, et al. “Efficacy and bleeding complications among patients randomized to enoxaparin or unfractionated heparin for antithrombin therapy in non-ST-Segment elevation acute coronary syndromes: a systematic overview.” Jama 292, no. 1 (July 7, 2004): 89–96. https://doi.org/10.1001/jama.292.1.89.
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• Chang, Wei-Ching, Eric Boersma, Christopher B. Granger, Robert A. Harrington, Robert M. Califf, Maarten L. Simoons, Neal S. Kleiman, Paul W. Armstrong, and Paul W. GUSTO-IIb and PURSUIT Investigators. “Dynamic prognostication in non-ST-elevation acute coronary syndromes: insights from GUSTO-IIb and PURSUIT.” Am Heart J 148, no. 1 (July 2004): 62–71. https://doi.org/10.1016/j.ahj.2003.05.004.
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• Reed, Shelby D., Joëlle Y. Friedman, Eric J. Velazquez, Ari Gnanasakthy, Robert M. Califf, and Kevin A. Schulman. “Multinational economic evaluation of valsartan in patients with chronic heart failure: results from the Valsartan Heart Failure Trial (Val-HeFT).” Am Heart J 148, no. 1 (July 2004): 122–28. https://doi.org/10.1016/j.ahj.2003.12.040.
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• Waters, Richard E., Kanwar P. Singh, Matthew T. Roe, Mat Lotfi, Michael H. Sketch, Kenneth W. Mahaffey, L Kristin Newby, et al. “Rationale and strategies for implementing community-based transfer protocols for primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction.” J Am Coll Cardiol 43, no. 12 (June 16, 2004): 2153–59. https://doi.org/10.1016/j.jacc.2003.12.057.
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• Labinaz, Marino, Padma Kaul, Robert A. Harrington, Wei-Ching Chang, Neal S. Kleiman, Maarten L. Simoons, Eric Boersma, et al. “Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trial.” Can J Cardiol 20, no. 8 (June 2004): 773–78.
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• O’Shea, J Conor, Judith M. Kramer, Robert M. Califf, and Eric D. Peterson. “Part I: Identifying holes in the safety net.” Am Heart J 147, no. 6 (June 2004): 977–84. https://doi.org/10.1016/j.ahj.2004.03.001.
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• Peterson, Eric D., John W. Hirshfeld, T Bruce Ferguson, Judith M. Kramer, Robert M. Califf, and Larry G. Kessler. “Part II: Sealing holes in the safety net.” Am Heart J 147, no. 6 (June 2004): 985–90. https://doi.org/10.1016/j.ahj.2004.03.002.
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• Califf, Robert M. “Benefit the patient, manage the risk: a system goal.” Pharmacoepidemiol Drug Saf 13, no. 5 (May 2004): 269–76. https://doi.org/10.1002/pds.957.
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• March, John S., Susan G. Silva, Scott Compton, Ginger Anthony, Joseph DeVeaugh-Geiss, Robert Califf, and Ranga Krishnan. “The Child and Adolescent Psychiatry Trials Network (CAPTN).” J Am Acad Child Adolesc Psychiatry 43, no. 5 (May 2004): 515–18. https://doi.org/10.1097/00004583-200405000-00004.
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• Gibson, C Michael, Juhana Karha, Sabina A. Murphy, James A. de Lemos, David A. Morrow, Robert P. Giugliano, Mathew T. Roe, et al. “Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction.” J Am Coll Cardiol 43, no. 7 (April 7, 2004): 1170–76. https://doi.org/10.1016/j.jacc.2003.11.035.
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• Califf, Robert M. “Watching the WATCH trial: the role of sponsors and data monitoring committees.” J Card Fail 10, no. 2 (April 2004): 113–14. https://doi.org/10.1016/j.cardfail.2004.03.001.
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• Califf, Robert M., Vance Fowler, Christopher H. Cabell, and G Ralph Corey. “Novel approaches to clinical trials: device-related infections.” Am Heart J 147, no. 4 (April 2004): 599–604. https://doi.org/10.1016/j.ahj.2003.12.031.
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• Maas, Arthur C. P., Christina M. Wyatt, Cynthia L. Green, Galen S. Wagner, Kathleen M. Trollinger, James E. Pope, Anatoly Langer, et al. “Combining baseline clinical descriptors and real-time response to therapy: the incremental prognostic value of continuous ST-segment monitoring in acute myocardial infarction.” Am Heart J 147, no. 4 (April 2004): 698–704. https://doi.org/10.1016/j.ahj.2003.08.014.
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• Bittl, John A., Derek P. Chew, Eric J. Topol, David F. Kong, and Robert M. Califf. “Meta-analysis of randomized trials of percutaneous transluminal coronary angioplasty versus atherectomy, cutting balloon atherotomy, or laser angioplasty.” J Am Coll Cardiol 43, no. 6 (March 17, 2004): 936–42. https://doi.org/10.1016/j.jacc.2003.10.039.
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• Quinn, Martin J., Herbert D. Aronow, Robert M. Califf, Deepak L. Bhatt, Shelly Sapp, Neal S. Kleiman, Robert A. Harrington, David F. Kong, David E. Kandzari, and Eric J. Topol. “Aspirin dose and six-month outcome after an acute coronary syndrome.” J Am Coll Cardiol 43, no. 6 (March 17, 2004): 972–78. https://doi.org/10.1016/j.jacc.2003.09.059.
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• Berger, Peter B., Michael H. Sketch, and Robert M. Califf. “Choosing between percutaneous coronary intervention and coronary artery bypass grafting for patients with multivessel disease: what can we learn from the Arterial Revascularization Therapy Study (ARTS)?” Circulation 109, no. 9 (March 9, 2004): 1079–81. https://doi.org/10.1161/01.CIR.0000121313.22131.41.
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• Kandzari, David E., Alan Chu, Bruce R. Brodie, Thomas A. Stuckey, James B. Hermiller, George W. Vetrovec, Karen L. Hannan, et al. “Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study).” Am J Cardiol 93, no. 5 (March 1, 2004): 636–39. https://doi.org/10.1016/j.amjcard.2003.11.038.
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• Kandzari, David E., Vic Hasselblad, James E. Tcheng, Gregg W. Stone, Robert M. Califf, Adnan Kastrati, Franz-Josef Neumann, et al. “Improved clinical outcomes with abciximab therapy in acute myocardial infarction: a systematic overview of randomized clinical trials.” Am Heart J 147, no. 3 (March 2004): 457–62. https://doi.org/10.1016/j.ahj.2003.08.011.
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• Kong, David F., Eric L. Eisenstein, Michael H. Sketch, James P. Zidar, Thomas J. Ryan, Robert A. Harrington, Mark F. Newman, Peter K. Smith, Daniel B. Mark, and Robert M. Califf. “Economic impact of drug-eluting stents on hospital systems: a disease-state model.” Am Heart J 147, no. 3 (March 2004): 449–56. https://doi.org/10.1016/j.ahj.2003.11.005.
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• McAnulty, John H. “Valsartan, captopril, or both in myocardial infarction.” N Engl J Med 350, no. 9 (February 26, 2004): 943–45. https://doi.org/10.1056/NEJM200402263500918.
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• Gurm, Hitinder S., A Michael Lincoff, David Lee, WH Wilson Tang, Gang Jia, Joan E. Booth, Robert M. Califf, et al. “Outcome of acute ST-segment elevation myocardial infarction in diabetics treated with fibrinolytic or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: lessons from the GUSTO V trial.” J Am Coll Cardiol 43, no. 4 (February 18, 2004): 542–48. https://doi.org/10.1016/j.jacc.2003.09.038.
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• Nabel, Elizabeth G., Harry P. Selker, Robert M. Califf, John G. Canto, Jie J. Cao, Patrice Desvigne-Nikkens, Robert J. Goldberg, et al. “Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 3: diagnosis and treatment of acute cardiac ischemia: gender issues.” Circulation 109, no. 6 (February 17, 2004): e50–52. https://doi.org/10.1161/01.CIR.0000116208.41269.75.
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• Kandzari, David E., Christopher B. Granger, Maarten L. Simoons, Harvey D. White, John Simes, Kenneth W. Mahaffey, Joel Gore, et al. “Risk factors for intracranial hemorrhage and nonhemorrhagic stroke after fibrinolytic therapy (from the GUSTO-i trial).” Am J Cardiol 93, no. 4 (February 15, 2004): 458–61. https://doi.org/10.1016/j.amjcard.2003.10.043.
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• Pieper, Karen S., Anastasios A. Tsiatis, Marie Davidian, Vic Hasselblad, Neal S. Kleiman, Eric Boersma, Wei-Ching Chang, et al. “Differential treatment benefit of platelet glycoprotein IIb/IIIa inhibition with percutaneous coronary intervention versus medical therapy for acute coronary syndromes: exploration of methods.” Circulation 109, no. 5 (February 10, 2004): 641–46. https://doi.org/10.1161/01.CIR.0000112570.97220.89.
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• James, Stefan K., Agneta Siegbahn, Paul Armstrong, Elliott Barnathan, Robert Califf, Maarten L. Simoons, and Lars Wallentin. “Activation of the inflammation, coagulation, and fibrinolysis systems, without influence of abciximab infusion in patients with non-ST-elevation acute coronary syndromes treated with dalteparin: a GUSTO IV substudy.” Am Heart J 147, no. 2 (February 2004): 267–74. https://doi.org/10.1016/j.ahj.2003.09.014.
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• James, Stefan K., Bertil Lindahl, Paul Armstrong, Robert Califf, ML Maarten L. Simoons, Per Venge, Lars Wallentin, and Lars GUSTO-IV ACS Investigators. “A rapid troponin I assay is not optimal for determination of troponin status and prediction of subsequent cardiac events at suspicion of unstable coronary syndromes.” International Journal of Cardiology 93, no. 2–3 (February 2004): 113–20. https://doi.org/10.1016/s0167-5273(03)00157-8.
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• Kaul, Padma, L Kristin Newby, Yuling Fu, Daniel B. Mark, Robert M. Califf, Eric J. Topol, Phil Aylward, Christopher B. Granger, Frans Van de Werf, and Paul W. Armstrong. “International differences in evolution of early discharge after acute myocardial infarction.” Lancet (London, England) 363, no. 9408 (February 2004): 511–17. https://doi.org/10.1016/s0140-6736(04)15536-0.
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• McGuire, Darren K., L Kristin Newby, Manjushri V. Bhapkar, David J. Moliterno, Judith S. Hochman, Werner W. Klein, W Douglas Weaver, et al. “Association of diabetes mellitus and glycemic control strategies with clinical outcomes after acute coronary syndromes.” Am Heart J 147, no. 2 (February 2004): 246–52. https://doi.org/10.1016/j.ahj.2003.07.024.
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• Roe, M. T., K. W. Mahaffey, R. Kilaru, J. H. Alexander, K. M. Akkerhuis, M. L. Simoons, R. A. Harrington, et al. “Creatine kinase-MB elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes.” Eur Heart J 25, no. 4 (February 2004): 313–21. https://doi.org/10.1016/j.ehj.2003.12.009.
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• Cowper, Patricia A., Elizabeth R. DeLong, David J. Whellan, Nancy M. Allen LaPointe, and Robert M. Califf. “Economic effects of beta-blocker therapy in patients with heart failure.” Am J Med 116, no. 2 (January 15, 2004): 104–11. https://doi.org/10.1016/j.amjmed.2003.07.016.
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• Rebeiz, Abdallah G., Matthew T. Roe, John H. Alexander, Kenneth W. Mahaffey, Christopher B. Granger, Eric D. Peterson, Robert M. Califf, and Robert A. Harrington. “Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes.” Am J Med 116, no. 2 (January 15, 2004): 119–29. https://doi.org/10.1016/j.amjmed.2003.09.028.
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• Califf, Robert M. “Defining the balance of risk and benefit in the era of genomics and proteomics.” Health Aff (Millwood) 23, no. 1 (January 2004): 77–87. https://doi.org/10.1377/hlthaff.23.1.77.
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• DeMets, David L., Thomas R. Fleming, Frank Rockhold, Barry Massie, Thomas Merchant, Alan Meisel, Barbara Mishkin, Janet Wittes, David Stump, and Robert Califf. “Liability issues for data monitoring committee members.” Clin Trials 1, no. 6 (2004): 525–31. https://doi.org/10.1191/1740774504cn54oa.
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• DeMets, David, Robert Califf, Dennis Dixon, Susan Ellenberg, Thomas Fleming, Peter Held, Desmond Julian, et al. “Issues in regulatory guidelines for data monitoring committees.” Clin Trials 1, no. 2 (2004): 162–69. https://doi.org/10.1191/1740774504cn019xx.
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• Mark, D. B., and R. M. Califf. “Introduction of a new section: Cardiology Fellows - Quick Evidence-Based Consult.” American Heart Journal 147, no. 1 (January 1, 2004): 1. https://doi.org/10.1016/j.ahj.2003.11.002.
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• Alexander, John H., Robert A. Harrington, Manju Bhapkar, Kenneth W. Mahaffey, A Michael Lincoff, E Magnus Ohman, Peter Klootwijk, et al. “Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes.” Am J Med 115, no. 8 (December 1, 2003): 613–19. https://doi.org/10.1016/j.amjmed.2003.08.007.
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• Kramer, Judith M., L Kristin Newby, Wei Ching Chang, R John Simes, Frans Van de Werf, Christopher B. Granger, Kerry L. Lee, et al. “International variation in the use of evidence-based medicines for acute coronary syndromes.” Eur Heart J 24, no. 23 (December 2003): 2133–41. https://doi.org/10.1016/j.ehj.2003.09.018.
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• Newby, L Kristin, Manjushri V. Bhapkar, Harvey D. White, David J. Moliterno, Nancy M Allen LaPointe, David E. Kandzari, Freek W. A. Verheugt, et al. “Aspirin use post-acute coronary syndromes: intolerance, bleeding and discontinuation.” Journal of Thrombosis and Thrombolysis 16, no. 3 (December 2003): 119–28. https://doi.org/10.1023/b:thro.0000024050.78728.35.
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• Stamler, Jonathan S., Robert L. Taber, and Robert M. Califf. “Translation of academic discovery into societal benefit: proposal for a balanced approach--part 2.” Am J Med 115, no. 8 (December 1, 2003): 683–88. https://doi.org/10.1016/j.amjmed.2003.10.003.
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• Pfeffer, Marc A., John J. V. McMurray, Eric J. Velazquez, Jean-Lucien Rouleau, Lars Køber, Aldo P. Maggioni, Scott D. Solomon, et al. “Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both.” N Engl J Med 349, no. 20 (November 13, 2003): 1893–1906. https://doi.org/10.1056/NEJMoa032292.
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• Allen LaPointe, Nancy M., Anita Chen, Bradley Hammill, Elizabeth DeLong, Judith M. Kramer, and Robert M. Califf. “Evaluation of the dofetilide risk-management program.” Am Heart J 146, no. 5 (November 2003): 894–901. https://doi.org/10.1016/S0002-8703(03)00409-5.
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• Califf, R. M. “Issues facing clinical trials of the future.” Journal of Internal Medicine 254, no. 5 (November 2003): 426–33. https://doi.org/10.1046/j.1365-2796.2003.01238.x.
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• Mahaffey, Kenneth W., Bruce E. Lewis, Nancy M. Wildermann, Scott D. Berkowitz, Renee M. Oliverio, Mark A. Turco, Yoseph Shalev, et al. “The anticoagulant therapy with bivalirudin to assist in the performance of percutaneous coronary intervention in patients with heparin-induced thrombocytopenia (ATBAT) study: main results.” J Invasive Cardiol 15, no. 11 (November 2003): 611–16.
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• Stamler, Jonathan S., Robert L. Taber, and Robert M. Califf. “Translation of academic discovery into societal benefit: proposal for a balanced approach--part 1.” Am J Med 115, no. 7 (November 2003): 596–99. https://doi.org/10.1016/j.amjmed.2003.09.006.
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• Califf, R. M. “Supplement on Acute Coronary Syndromes: Introduction.” Circulation 108, no. 16 SUPPL. (October 21, 2003).
• Califf, Robert M. “Supplement on acute coronary syndromes: introduction.” Circulation 108, no. 16 Suppl 1 (October 21, 2003): III1–5. https://doi.org/10.1161/01.CIR.0000086949.66085.f7.
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• Roe, Matthew T., E Magnus Ohman, Charles V. Pollack, Eric D. Peterson, Ralph G. Brindis, Robert A. Harrington, Robert H. Christenson, Sidney C. Smith, Robert M. Califf, and W Brian Gibler. “Changing the model of care for patients with acute coronary syndromes.” American Heart Journal 146, no. 4 (October 2003): 605–12. https://doi.org/10.1016/s0002-8703(03)00388-0.
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• Savonitto, S., P. W. Armstrong, A. M. Lincoff, G. Jia, C. A. Sila, J. Booth, P. Terrosu, et al. “Risk of intracranial haemorrhage with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy in acute myocardial infarction. Dichotomous response as a function of age in the GUSTO V trial.” Eur Heart J 24, no. 20 (October 2003): 1807–14. https://doi.org/10.1016/j.ehj.2003.07.004.
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• Kong, David F., Vic Hasselblad, Robert A. Harrington, Harvey D. White, James E. Tcheng, David E. Kandzari, Eric J. Topol, and Robert M. Califf. “Meta-analysis of survival with platelet glycoprotein IIb/IIIa antagonists for percutaneous coronary interventions.” The American Journal of Cardiology 92, no. 6 (September 2003): 651–55. https://doi.org/10.1016/s0002-9149(03)00816-6.
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• Reddan, Donal N., Lynda Anne Szczech, Robert H. Tuttle, Linda K. Shaw, Robert H. Jones, Steve J. Schwab, Mark Stafford Smith, Robert M. Califf, Daniel B. Mark, and William F. Owen. “Chronic kidney disease, mortality, and treatment strategies among patients with clinically significant coronary artery disease.” J Am Soc Nephrol 14, no. 9 (September 2003): 2373–80. https://doi.org/10.1097/01.asn.0000083900.92829.f5.
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• Wong, Cheuk-Kit, Harvey D. White, Robert G. Wilcox, Douglas A. Criger, Robert M. Califf, Eric J. Topol, and E Magnus Ohman. “Significance of atrial fibrillation during acute myocardial infarction, and its current management: insights from the GUSTO-3 trial.” Cardiac Electrophysiology Review 7, no. 3 (September 2003): 201–7. https://doi.org/10.1023/b:cepr.0000012382.81986.47.
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• Krantz, Mori J., Bridget A. Martell, Julia H. Arnsten, and Marc N. Gourevitch. “Medications that prolong the QT interval.” Jama 290, no. 8 (August 27, 2003): 1025. https://doi.org/10.1001/jama.290.8.1025-a.
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• Califf, Robert M., and Lawrence H. Muhlbaier. “Health Insurance Portability and Accountability Act (HIPAA): must there be a trade-off between privacy and quality of health care, or can we advance both?” Circulation 108, no. 8 (August 26, 2003): 915–18. https://doi.org/10.1161/01.CIR.0000085720.65685.90.
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• Serebruany, Victor L., Alexander H. Glassman, Alex I. Malinin, Charles B. Nemeroff, Dominique L. Musselman, Louis T. van Zyl, Mitchell S. Finkel, et al. “Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy.” Circulation 108, no. 8 (August 26, 2003): 939–44. https://doi.org/10.1161/01.CIR.0000085163.21752.0A.
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• James, Stefan, Paul Armstrong, Robert Califf, Maarten L. Simoons, Per Venge, Lars Wallentin, and Bertil Lindahl. “Troponin T levels and risk of 30-day outcomes in patients with the acute coronary syndrome: prospective verification in the GUSTO-IV trial.” The American Journal of Medicine 115, no. 3 (August 2003): 178–84. https://doi.org/10.1016/s0002-9343(03)00348-6.
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• Tolleson, Thaddeus R., L Kristin Newby, Robert A. Harrington, Manjushri V. Bhapkar, Freek W. A. Verheugt, Peter B. Berger, David J. Moliterno, et al. “Frequency of stent thrombosis after acute coronary syndromes (from the SYMPHONY and 2nd SYMPHONY trials).” The American Journal of Cardiology 92, no. 3 (August 2003): 330–33. https://doi.org/10.1016/s0002-9149(03)00641-6.
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• Velazquez, Eric J., Marc A. Pfeffer, John V. McMurray, Aldo P. Maggioni, Jean Lucien Rouleau, Frans Van de Werf, Lars Kober, et al. “VALsartan In Acute myocardial iNfarcTion (VALIANT) trial: baseline characteristics in context.” Eur J Heart Fail 5, no. 4 (August 2003): 537–44. https://doi.org/10.1016/s1388-9842(03)00112-0.
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• Topol, Eric J., Donald Easton, Robert A. Harrington, Pierre Amarenco, Robert M. Califf, Carmen Graffagnino, Stephen Davis, et al. “Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease.” Circulation 108, no. 4 (July 29, 2003): 399–406. https://doi.org/10.1161/01.CIR.0000084501.48570.F6.
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• James, Stefan K., Bertil Lindahl, Agneta Siegbahn, Mats Stridsberg, Per Venge, Paul Armstrong, Elliot S. Barnathan, et al. “N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease: a Global Utilization of Strategies To Open occluded arteries (GUSTO)-IV substudy.” Circulation 108, no. 3 (July 22, 2003): 275–81. https://doi.org/10.1161/01.CIR.0000079170.10579.DC.
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• Califf, Robert M., Michael A. Morse, Janet Wittes, Steven N. Goodman, Daniel K. Nelson, David L. DeMets, R Peter Iafrate, and Jeremy Sugarman. “Toward protecting the safety of participants in clinical trials.” Control Clin Trials 24, no. 3 (June 2003): 256–71. https://doi.org/10.1016/s0197-2456(03)00005-9.
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• Williams, R Taylor, Lakshmi V. Damaraju, Mary Ann Mascelli, Elliot S. Barnathan, Robert M. Califf, Maarten L. Simoons, Efthymios N. Deliargyris, and David C. Sane. “Anti-platelet factor 4/heparin antibodies: an independent predictor of 30-day myocardial infarction after acute coronary ischemic syndromes.” Circulation 107, no. 18 (May 13, 2003): 2307–12. https://doi.org/10.1161/01.CIR.0000066696.57519.AF.
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• Belch, Jill J. F., Eric J. Topol, Giancarlo Agnelli, Michel Bertrand, Robert M. Califf, Denis L. Clement, Mark A. Creager, et al. “Critical issues in peripheral arterial disease detection and management: a call to action.” Arch Intern Med 163, no. 8 (April 28, 2003): 884–92. https://doi.org/10.1001/archinte.163.8.884.
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• Al-Khatib, Sana M., Nancy M Allen LaPointe, Judith M. Kramer, and Robert M. Califf. “What clinicians should know about the QT interval.” Jama 289, no. 16 (April 23, 2003): 2120–27. https://doi.org/10.1001/jama.289.16.2120.
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• Giugliano, Robert P., Matthew T. Roe, Robert A. Harrington, C Michael Gibson, Uwe Zeymer, Frans Van de Werf, Kenneth W. Baran, et al. “Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction: results of the integrilin and tenecteplase in acute myocardial infarction (INTEGRITI) Phase II Angiographic Trial.” J Am Coll Cardiol 41, no. 8 (April 16, 2003): 1251–60. https://doi.org/10.1016/s0735-1097(03)00123-2.
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• Califf, R. M. “Insulin resistance: A global epidemic in need of effective therapies.” European Heart Journal, Supplement 5, no. C (April 1, 2003). https://doi.org/10.1016/S1520-765X(03)90045-9.
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• Campbell, William H., and Robert M. Califf. “Improving communication of drug risks to prevent patient injury: proceedings of a workshop.” Pharmacoepidemiol Drug Saf 12, no. 3 (April 2003): 183–94. https://doi.org/10.1002/pds.761.
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• LaPointe, Nancy M Allen, Sana M. Al-Khatib, Judith M. Kramer, and Robert M. Califf. “Knowledge deficits related to the QT interval could affect patient safety.” Ann Noninvasive Electrocardiol 8, no. 2 (April 2003): 157–60. https://doi.org/10.1046/j.1542-474x.2003.08211.x.
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• Reddan, Donal, Lynda A. Szczech, Susan O’Shea, and Robert M. Califf. “Anticoagulation in acute cardiac care in patients with chronic kidney disease.” Am Heart J 145, no. 4 (April 2003): 586–94. https://doi.org/10.1067/mhj.2003.168.
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• Tcheng, James E., Mina Madan, J Conor O’Shea, Eric A. Cohen, Christopher E. Buller, A Michael Lincoff, Jeffrey J. Popma, et al. “Ethics and equipoise: rationale for a placebo-controlled study design of platelet glycoprotein IIb/IIIa inhibition in coronary intervention.” Journal of Interventional Cardiology 16, no. 2 (April 2003): 97–105. https://doi.org/10.1046/j.1540-8183.2003.08020.x.
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• Califf, Robert M., and David P. Faxon. “Need for centers to care for patients with acute coronary syndromes.” Circulation 107, no. 11 (March 25, 2003): 1467–70. https://doi.org/10.1161/01.cir.0000065160.19016.26.
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• Felker, G Michael, Raymond L. Benza, A Bleakley Chandler, Jeffrey D. Leimberger, Michael S. Cuffe, Robert M. Califf, Mihai Gheorghiade, Christopher M. O’Connor, and Christopher M. OPTIME-CHF Investigators. “Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.” J Am Coll Cardiol 41, no. 6 (March 19, 2003): 997–1003. https://doi.org/10.1016/s0735-1097(02)02968-6.
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• Khadour, Fadi H., Yuling Fu, Wei-Ching Chang, Xin Ma, Dan Mark, Christopher B. Granger, Eric J. Topol, Robert M. Califf, Paul W. Armstrong, and Paul W. GUSTO IIb investigators. “Impact of on-site cardiac interventional facilities on management and outcome of patients with acute coronary syndromes.” Can J Cardiol 19, no. 3 (March 15, 2003): 257–63.
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• Al-Khatib, Sana M., Amanda L. Stebbins, Robert M. Califf, Kerry L. Lee, Christopher B. Granger, Harvey D. White, Paul W. Armstrong, Eric J. Topol, E Magnus Ohman, and E Magnus GUSTO-III trial. “Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: results from the GUSTO-III trial.” Am Heart J 145, no. 3 (March 2003): 515–21. https://doi.org/10.1067/mhj.2003.170.
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• Hersi, A., Y. Fu, B. Wong, K. W. Mahaffey, R. A. Harrington, R. M. Califf, F. Van de Werf, P. W. Armstrong, and P. W. PARAGON-B Investigators. “Does the discharge ECG provide additional prognostic insight(s) in non-ST elevation ACS patients from that acquired on admission?” European Heart Journal 24, no. 6 (March 2003): 522–31. https://doi.org/10.1016/s0195-668x(02)00525-0.
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• James, Stefan K., Paul Armstrong, Elliott Barnathan, Robert Califf, Bertil Lindahl, Agneta Siegbahn, Maarten L. Simoons, et al. “Troponin and C-reactive protein have different relations to subsequent mortality and myocardial infarction after acute coronary syndrome: a GUSTO-IV substudy.” Journal of the American College of Cardiology 41, no. 6 (March 2003): 916–24. https://doi.org/10.1016/s0735-1097(02)02969-8.
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• Rao, Sunil V., and Robert M. Califf. “Lessons learned from clinical trials: a roundtable discussion.” Crit Pathw Cardiol 2, no. 1 (March 2003): 55–59. https://doi.org/10.1097/01.HPC.0000056943.80804.80.
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• Batchelor, Wayne B., Daniel B. Mark, J David Knight, Christopher B. Granger, Paul W. Armstrong, Robert M. Califf, and Eric D. Peterson. “Development and validation of a simple model to predict severe coronary artery disease after myocardial infarction: potential impact on cardiac catheterization use in the United States and Canada.” American Heart Journal 145, no. 2 (February 2003): 349–55. https://doi.org/10.1067/mhj.2003.111.
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• Cho, Leslie, Deepak L. Bhatt, Steve P. Marso, Danielle Brennan, David R. Holmes, Robert M. Califf, and Eric J. Topol. “An invasive strategy is associated with decreased mortality in patients with unstable angina and non-ST-elevation myocardial infarction: GUSTO IIb trial.” The American Journal of Medicine 114, no. 2 (February 2003): 106–11. https://doi.org/10.1016/s0002-9343(02)01446-8.
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• Curtis, Lesley H., Truls Østbye, Veronica Sendersky, Steve Hutchison, Nancy M. Allen LaPointe, Sana M. Al-Khatib, Sally Usdin Yasuda, et al. “Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients.” Am J Med 114, no. 2 (February 1, 2003): 135–41. https://doi.org/10.1016/s0002-9343(02)01455-9.
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• Kaul, Padma, L Kristin Newby, Yuling Fu, Vic Hasselblad, Kenneth W. Mahaffey, Robert H. Christenson, Robert A. Harrington, et al. “Troponin T and quantitative ST-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients.” Journal of the American College of Cardiology 41, no. 3 (February 2003): 371–80. https://doi.org/10.1016/s0735-1097(02)02824-3.
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• Selker, Harry P., Merritt H. Raitt, Christopher H. Schmid, Michael M. Laks, Joni R. Beshansky, John L. Griffith, Robert M. Califf, et al. “Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction.” The American Journal of Cardiology 91, no. 3 (February 2003): 280–86. https://doi.org/10.1016/s0002-9149(02)03155-7.
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• Novak, Joel W. “Clinical-trial agreements between medical schools and industry.” N Engl J Med 348, no. 5 (January 30, 2003): 476–78. https://doi.org/10.1056/NEJM200301303480523.
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• Yancy, William S., Eric C. Westman, Patricia A. French, and Robert M. Califf. “Diets and clinical coronary events: the truth is out there.” Circulation 107, no. 1 (January 7, 2003): 10–16. https://doi.org/10.1161/01.cir.0000049205.35749.00.
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• Al-Khatib, Sana M., Nancy M Allen LaPointe, Lesley H. Curtis, Judith M. Kramer, Joslyn Swann, Peter Honig, and Robert M. Califf. “Outpatient prescribing of antiarrhythmic drugs from 1995 to 2000.” The American Journal of Cardiology 91, no. 1 (January 2003): 91–94. https://doi.org/10.1016/s0002-9149(02)03008-4.
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• Califf, R. M. “Cardiac markers in acute coronary syndromes-refining our knowledge.” Eur Heart J 24, no. 2 (January 2003): 136–37. https://doi.org/10.1016/s0195-668x(02)00798-4.
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• Newby, L. K., M. V. Bhapkar, H. D. White, E. J. Topol, F. C. Dougherty, R. A. Harrington, M. C. Smith, L. F. Asarch, R. M. Califf, and R. M. SYMPHONY and 2nd SYMPHONY Investigators. “Predictors of 90-day outcome in patients stabilized after acute coronary syndromes.” Eur Heart J 24, no. 2 (January 2003): 172–81. https://doi.org/10.1016/s0195-668x(02)00325-1.
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• Newby, L. K., V. Hasselblad, P. W. Armstrong, F. Van de Werf, D. B. Mark, H. D. White, E. J. Topol, and R. M. Califf. “Time-based risk assessment after myocardial infarction. Implications for timing of discharge and applications to medical decision-making.” Eur Heart J 24, no. 2 (January 2003): 182–89. https://doi.org/10.1016/s0195-668x(02)00301-9.
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• Abman, Steven H., and John P. Kinsella. “Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.” Lancet (London, England) 360, no. 9350 (December 2002): 2076–77. https://doi.org/10.1016/s0140-6736(02)12000-9.
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• Blankenship, James C., Craig Balog, Shelly K. Sapp, Robert M. Califf, A Michael Lincoff, James E. Tcheng, and Eric J. Topol. “Reduction in vascular access site bleeding in sequential abciximab coronary intervention trials.” Catheter Cardiovasc Interv 57, no. 4 (December 2002): 476–83. https://doi.org/10.1002/ccd.10322.
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• Califf, Robert M. “Heart failure roundtable: beta-blockers in the elderly. Introduction.” Postgrad Med 112, no. 6 Suppl Heart (December 2002): 5. https://doi.org/10.3810/pgm.12.2002.suppl24.124.
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• Califf, Robert M., Eric D. Peterson, Raymond J. Gibbons, Arthur Garson, Ralph G. Brindis, George A. Beller, Sidney C. Smith, Sidney C. American College of Cardiology, and Sidney C. American Heart Association. “Integrating quality into the cycle of therapeutic development.” Journal of the American College of Cardiology 40, no. 11 (December 2002): 1895–1901. https://doi.org/10.1016/s0735-1097(02)02537-8.
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• Califf, Robert M., and Karen P. Alexander. “Cardiovascular research in the elderly: challenges, opportunities, and impact.” Postgrad Med 112, no. 6 Suppl Heart (December 2002): 6–11. https://doi.org/10.3810/pgm.12.2002.suppl24.125.
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• Mukherjee, Debabrata, Kenneth W. Mahaffey, David J. Moliterno, Robert A. Harrington, Jay S. Yadav, Karen S. Pieper, Dianne Gallup, et al. “Promise of combined low-molecular-weight heparin and platelet glycoprotein IIb/IIIa inhibition: results from Platelet IIb/IIIa Antagonist for the Reduction of Acute coronary syndrome events in a Global Organization Network B (PARAGON B).” Am Heart J 144, no. 6 (December 2002): 995–1002. https://doi.org/10.1067/mhj.2002.126118.
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• Newby, L Kristin, Joseph S. Alpert, E Magnus Ohman, Kristian Thygesen, and Robert M. Califf. “Changing the diagnosis of acute myocardial infarction: implications for practice and clinical investigations.” Am Heart J 144, no. 6 (December 2002): 957–80. https://doi.org/10.1067/mhj.2002.129778.
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• O’Shea, J Conor, Robert G. Wilcox, Allan M. Skene, Amanda L. Stebbins, Christopher B. Granger, Paul W. Armstrong, Christoph Bode, et al. “Comparison of outcomes of patients with myocardial infarction when living alone versus those not living alone.” The American Journal of Cardiology 90, no. 12 (December 2002): 1374–77. https://doi.org/10.1016/s0002-9149(02)02876-x.
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• Lincoff, A Michael, Robert M. Califf, Frans Van de Werf, James T. Willerson, Harvey D. White, Paul W. Armstrong, Victor Guetta, et al. “Mortality at 1 year with combination platelet glycoprotein IIb/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trial.” Jama 288, no. 17 (November 6, 2002): 2130–35. https://doi.org/10.1001/jama.288.17.2130.
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• Anderson, Mark E., Sana M. Al-Khatib, Dan M. Roden, Robert M. Califf, and Robert M. Duke Clinical Research Institute/American Heart Journal Expert Meeting on Repolarization Changes. “Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management.” American Heart Journal 144, no. 5 (November 2002): 769–81. https://doi.org/10.1067/mhj.2002.125804.
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• Califf, R. M. “Introduction: Redefining acute coronary syndrome care in the era of aggressive revascularization.” Clinical Cardiology 25, no. 11 SUPPL. 1 (November 1, 2002): 1.
• Califf, R. M. “Matching resources to treatment decisions for patients with acute coronary syndromes.” Clinical Cardiology 25, no. 11 SUPPL. 1 (November 1, 2002).
• Califf, R. M. “Conclusion.” Clinical Cardiology 25, no. 11 SUPPL. 1 (November 1, 2002): 33.
• Califf, Robert M. “Matching resources to treatment decisions for patients with acute coronary syndromes.” Clin Cardiol 25, no. 11 Suppl 1 (November 2002): I2–8. https://doi.org/10.1002/clc.4960251303.
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• Islam, M Ashequl, James C. Blankenship, Craig Balog, Elias A. Iliadis, A Michael Lincoff, James E. Tcheng, Robert M. Califf, Eric J. Topol, and Eric J. EPISTENT Investigators. “Effect of abciximab on angiographic complications during percutaneous coronary stenting in the Evaluation of Platelet IIb/IIIa Inhibition in Stenting Trial (EPISTENT).” The American Journal of Cardiology 90, no. 9 (November 2002): 916–21. https://doi.org/10.1016/s0002-9149(02)02653-x.
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• Schulman, Kevin A., Damon M. Seils, Justin W. Timbie, Jeremy Sugarman, Lauren A. Dame, Kevin P. Weinfurt, Daniel B. Mark, and Robert M. Califf. “A national survey of provisions in clinical-trial agreements between medical schools and industry sponsors.” N Engl J Med 347, no. 17 (October 24, 2002): 1335–41. https://doi.org/10.1056/NEJMsa020349.
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• Califf, Robert M. “Evaluating the costs and effectiveness of cardiovascular therapies: who cares about economic analyses?” Stat Med 21, no. 19 (October 15, 2002): 2889–97. https://doi.org/10.1002/sim.1293.
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• Braunwald, Eugene, Elliott M. Antman, John W. Beasley, Robert M. Califf, Melvin D. Cheitlin, Judith S. Hochman, Robert H. Jones, et al. “ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients With Unstable Angina).” J Am Coll Cardiol 40, no. 7 (October 2, 2002): 1366–74. https://doi.org/10.1016/s0735-1097(02)02336-7.
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• Braunwald, Eugene, Elliott M. Antman, John W. Beasley, Robert M. Califf, Melvin D. Cheitlin, Judith S. Hochman, Robert H. Jones, et al. “ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--2002: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina).” Circulation 106, no. 14 (October 1, 2002): 1893–1900. https://doi.org/10.1161/01.cir.0000037106.76139.53.
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• James, S., P. Armstrong, R. Califf, S. Husted, F. Kontny, M. Niemminen, M. Pfisterer, M. L. Simoons, and L. Wallentin. “Safety and efficacy of abciximab combined with dalteparin in treatment of acute coronary syndromes.” European Heart Journal 23, no. 19 (October 2002): 1538–45. https://doi.org/10.1053/euhj.2002.3257.
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• Lee, Michael S., Andreas U. Wali, Venu Menon, Scott D. Berkowitz, Trevor D. Thompson, Robert M. Califf, Eric J. Topol, Christopher B. Granger, and Judith S. Hochman. “The determinants of activated partial thromboplastin time, relation of activated partial thromboplastin time to clinical outcomes, and optimal dosing regimens for heparin treated patients with acute coronary syndromes: a review of GUSTO-IIb.” J Thromb Thrombolysis 14, no. 2 (October 2002): 91–101. https://doi.org/10.1023/a:1023235926825.
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• Wong, C. -. K., H. D. White, R. G. Wilcox, D. A. Criger, R. M. Califf, E. J. Topol, E. M. Ohman, and E. M. GUSTO-III Investigators. “Management and outcome of patients with atrial fibrillation during acute myocardial infarction: the GUSTO-III experience. Global use of strategies to open occluded coronary arteries.” Heart 88, no. 4 (October 2002): 357–62. https://doi.org/10.1136/heart.88.4.357.
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• Batchelor, Wayne B., Thaddeus R. Tolleson, Yao Huang, Rhonda L. Larsen, R Michael Mantell, Patricia Dillard, Marie Davidian, et al. “Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, and Eptifibatide.” Circulation 106, no. 12 (September 17, 2002): 1470–76. https://doi.org/10.1161/01.cir.0000029744.01096.1f.
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• Hillegass, William B., Brigitta C. Brott, Gregory D. Chapman, Harry R. Phillips, Richard S. Stack, James E. Tcheng, and Robert M. Califf. “Relationship between activated clotting time during percutaneous intervention and subsequent bleeding complications.” Am Heart J 144, no. 3 (September 2002): 501–7. https://doi.org/10.1067/mhj.2002.123143.
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• Kereiakes, Dean J., A Michael Lincoff, Keaven M. Anderson, Robert Achenbach, Kamlesh Patel, Elliot Barnathan, Robert M. Califf, et al. “Abciximab survival advantage following percutaneous coronary intervention is predicted by clinical risk profile.” The American Journal of Cardiology 90, no. 6 (September 2002): 628–30. https://doi.org/10.1016/s0002-9149(02)02568-7.
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• Kong, David F., Vic Hasselblad, David E. Kandzari, L Kristin Newby, and Robert M. Califf. “Seeking the optimal aspirin dose in acute coronary syndromes.” The American Journal of Cardiology 90, no. 6 (September 2002): 622–25. https://doi.org/10.1016/s0002-9149(02)02566-3.
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• Labinaz, Marino, Mina Madan, J O’Conor O’Shea, Rakhi Kilaru, Wai Chin, Karen Pieper, Darren K. McGuire, et al. “Comparison of one-year outcomes following coronary artery stenting in diabetic versus nondiabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy [ESPRIT] Trial).” The American Journal of Cardiology 90, no. 6 (September 2002): 585–90. https://doi.org/10.1016/s0002-9149(02)02560-2.
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• Mehta, Rajendra H., Douglas A. Criger, Christopher B. Granger, Karen K. Pieper, Robert M. Califf, Eric J. Topol, and Eric R. Bates. “Patient outcomes after fibrinolytic therapy for acute myocardial infarction at hospitals with and without coronary revascularization capability.” Journal of the American College of Cardiology 40, no. 6 (September 2002): 1034–40. https://doi.org/10.1016/s0735-1097(02)02067-3.
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• Califf, Robert M., and David L. DeMets. “Principles from clinical trials relevant to clinical practice: Part II.” Circulation 106, no. 9 (August 27, 2002): 1172–75. https://doi.org/10.1161/01.cir.0000023218.39412.32.
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• Al Suwaidi, Jassim, Donal N. Reddan, Kathryn Williams, Karen S. Pieper, Robert A. Harrington, Robert M. Califf, Christopher B. Granger, et al. “Prognostic implications of abnormalities in renal function in patients with acute coronary syndromes.” Circulation 106, no. 8 (August 20, 2002): 974–80. https://doi.org/10.1161/01.cir.0000027560.41358.b3.
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• Califf, Robert M., and David L. DeMets. “Principles from clinical trials relevant to clinical practice: Part I.” Circulation 106, no. 8 (August 20, 2002): 1015–21. https://doi.org/10.1161/01.cir.0000023260.78078.bb.
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• Packer, Milton, Robert M. Califf, Marvin A. Konstam, Henry Krum, John J. McMurray, Jean-Lucien Rouleau, and Karl Swedberg. “Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE).” Circulation 106, no. 8 (August 20, 2002): 920–26. https://doi.org/10.1161/01.cir.0000029801.86489.50.
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• Glassman, Alexander H., Christopher M. O’Connor, Robert M. Califf, Karl Swedberg, Peter Schwartz, J Thomas Bigger, K Ranga Rama Krishnan, et al. “Sertraline treatment of major depression in patients with acute MI or unstable angina.” Jama 288, no. 6 (August 14, 2002): 701–9. https://doi.org/10.1001/jama.288.6.701.
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• DeMets, David L., and Robert M. Califf. “Lessons learned from recent cardiovascular clinical trials: Part II.” Circulation 106, no. 7 (August 13, 2002): 880–86. https://doi.org/10.1161/01.cir.0000023220.26465.89.
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• DeMets, David L., and Robert M. Califf. “Lessons learned from recent cardiovascular clinical trials: Part I.” Circulation 106, no. 6 (August 6, 2002): 746–51. https://doi.org/10.1161/01.cir.0000023219.51483.66.
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• Kent, David M., Rodney A. Hayward, John L. Griffith, Sandeep Vijan, Joni R. Beshansky, Robert M. Califf, and Harry P. Selker. “An independently derived and validated predictive model for selecting patients with myocardial infarction who are likely to benefit from tissue plasminogen activator compared with streptokinase.” Am J Med 113, no. 2 (August 1, 2002): 104–11. https://doi.org/10.1016/s0002-9343(02)01160-9.
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• Kottke-Marchant, K., M. C. Bahit, C. B. Granger, P. Zoldhelyi, D. Ardissino, L. Brooks, J. H. Griffin, et al. “Effect of hirudin vs heparin on haemostatic activity in patients with acute coronary syndromes; the GUSTO-IIb haemostasis substudy.” Eur Heart J 23, no. 15 (August 2002): 1202–12. https://doi.org/10.1053/euhj.2001.3074.
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• LaPointe, Nancy M Allen, Judith M. Kramer, Kevin P. Weinfurt, and Robert M. Califf. “Practitioner acceptance of the dofetilide risk-management program.” Pharmacotherapy 22, no. 8 (August 2002): 1041–46. https://doi.org/10.1592/phco.22.12.1041.33611.
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• Newby, L Kristin, Robert A. Harrington, Manjushri V. Bhapkar, Frans Van de Werf, Judith S. Hochman, Christopher B. Granger, R John Simes, et al. “An automated strategy for bedside aPTT determination and unfractionated heparin infusion adjustment in acute coronary syndromes: insights from PARAGON A.” J Thromb Thrombolysis 14, no. 1 (August 2002): 33–42. https://doi.org/10.1023/a:1022062204490.
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• Al-Khatib, Sana M., Christopher B. Granger, Yao Huang, Kerry L. Lee, Robert M. Califf, Maarten L. Simoons, Paul W. Armstrong, et al. “Sustained ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation: incidence, predictors, and outcomes.” Circulation 106, no. 3 (July 16, 2002): 309–12. https://doi.org/10.1161/01.cir.0000022692.49934.e3.
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• O’Connor, Christopher M., Eric J. Velazquez, Laura H. Gardner, Peter K. Smith, Mark F. Newman, Kevin P. Landolfo, Kerry L. Lee, Robert M. Califf, and Robert H. Jones. “Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank).” Am J Cardiol 90, no. 2 (July 15, 2002): 101–7. https://doi.org/10.1016/s0002-9149(02)02429-3.
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• Moya, Martin P., Andrew J. Gow, Robert M. Califf, Ronald N. Goldberg, and Jonathan S. Stamler. “Inhaled ethyl nitrite gas for persistent pulmonary hypertension of the newborn.” Lancet 360, no. 9327 (July 13, 2002): 141–43. https://doi.org/10.1016/S0140-6736(02)09385-6.
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• Anderson, R David, Harvey D. White, E Magnus Ohman, Galen S. Wagner, Mitchell W. Krucoff, Paul W. Armstrong, W Douglas Weaver, et al. “Predicting outcome after thrombolysis in acute myocardial infarction according to ST-segment resolution at 90 minutes: a substudy of the GUSTO-III trial. Global Use of Strategies To Open occluded coronary arteries.” Am Heart J 144, no. 1 (July 2002): 81–88. https://doi.org/10.1067/mhj.2002.123319.
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• Chang, W. -. C., R. A. Harrington, M. L. Simoons, R. M. Califf, A. M. Lincoff, P. W. Armstrong, and P. W. PURSUIT Investigators. “Does eptifibatide confer a greater benefit to patients with unstable angina than with non-ST segment elevation myocardial infarction? Insights from the PURSUIT Trial.” European Heart Journal 23, no. 14 (July 2002): 1102–11. https://doi.org/10.1053/euhj.2001.3151.
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• Gilchrist, Ian C., Scott D. Berkowitz, Trevor D. Thompson, Robert M. Califf, and Christopher B. Granger. “Heparin dosing and outcome in acute coronary syndromes: the GUSTO-IIb experience. Global Use of Strategies to Open Occluded Coronary Arteries.” Am Heart J 144, no. 1 (July 2002): 73–80. https://doi.org/10.1067/mhj.2002.123112.
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• Kandzari, David E., and Robert M. Califf. “TARGET versus GUSTO-IV: appropriate use of glycoprotein IIb/IIIa inhibitors in acute coronary syndromes and percutaneous coronary intervention.” Curr Opin Cardiol 17, no. 4 (July 2002): 332–39. https://doi.org/10.1097/00001573-200207000-00002.
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• Topol, Eric J., A Michael Lincoff, Dean J. Kereiakes, Neal S. Kleiman, Eric A. Cohen, James J. Ferguson, James E. Tcheng, Shelly Sapp, and Robert M. Califf. “Multi-year follow-up of abciximab therapy in three randomized, placebo-controlled trials of percutaneous coronary revascularization.” The American Journal of Medicine 113, no. 1 (July 2002): 1–6. https://doi.org/10.1016/s0002-9343(02)01145-2.
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• Whellan, David J., Elizabeth J. Cohen, David B. Matchar, and Robert M. Califf. “Disease management in healthcare organizations: results of in-depth interviews with disease management decision makers.” Am J Manag Care 8, no. 7 (July 2002): 633–41.
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• Aviles, Ronnier J., Arman T. Askari, Bertil Lindahl, Lars Wallentin, Gang Jia, E Magnus Ohman, Kenneth W. Mahaffey, et al. “Troponin T levels in patients with acute coronary syndromes, with or without renal dysfunction.” N Engl J Med 346, no. 26 (June 27, 2002): 2047–52. https://doi.org/10.1056/NEJMoa013456.
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• Newby, L Kristin, Arni Kristinsson, Manjushri V. Bhapkar, Philip E. Aylward, Alexios P. Dimas, Werner W. Klein, Darren K. McGuire, et al. “Early statin initiation and outcomes in patients with acute coronary syndromes.” Jama 287, no. 23 (June 19, 2002): 3087–95. https://doi.org/10.1001/jama.287.23.3087.
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• Califf, Robert M. “The need for a national infrastructure to improve the rational use of therapeutics.” Pharmacoepidemiol Drug Saf 11, no. 4 (June 2002): 319–27. https://doi.org/10.1002/pds.699.
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• Cantor, Warren J., L Kristin Newby, Robert H. Christenson, Robert H. Tuttle, Vic Hasselblad, Paul W. Armstrong, David J. Moliterno, et al. “Prognostic significance of elevated troponin I after percutaneous coronary intervention.” Journal of the American College of Cardiology 39, no. 11 (June 2002): 1738–44. https://doi.org/10.1016/s0735-1097(02)01877-6.
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• Julian, Desmond. “Absolute and relative truth in clinical trials.” Lancet (London, England) 359, no. 9321 (June 2002): 1945–46. https://doi.org/10.1016/s0140-6736(02)08750-0.
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• Newby, L Kristin, Robert M. Califf, Harvey D. White, Robert A. Harrington, Frans Van de Werf, Christopher B. Granger, R John Simes, Vic Hasselblad, and Paul W. Armstrong. “The failure of orally administered glycoprotein IIb/IIIa inhibitors to prevent recurrent cardiac events.” The American Journal of Medicine 112, no. 8 (June 2002): 647–58. https://doi.org/10.1016/s0002-9343(02)01106-3.
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• Ronner, Eelko, Eric Boersma, Gert-Jan Laarman, G Aernout Somsen, Robert A. Harrington, Jaap W. Deckers, Eric J. Topol, Robert M. Califf, and Maarten L. Simoons. “Early angioplasty in acute coronary syndromes without persistent ST-segment elevation improves outcome but increases the need for six-month repeat revascularization: an analysis of the PURSUIT Trial. Platelet glycoprotein IIB/IIIA in Unstable angina: Receptor Suppression Using Integrilin Therapy.” Journal of the American College of Cardiology 39, no. 12 (June 2002): 1924–29. https://doi.org/10.1016/s0735-1097(02)01897-1.
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• Shah, Monica R., Vic Hasselblad, Sandra S. Stinnett, Judith M. Kramer, Steven Grossman, Mihai Gheorghiade, Kirkwood F. Adams, Karl Swedberg, Robert M. Califf, and Christopher M. O’Connor. “Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure.” Eur J Heart Fail 4, no. 3 (June 2002): 297–304. https://doi.org/10.1016/s1388-9842(01)00202-1.
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• Szczech, L. A., P. J. Best, E. Crowley, M. M. Brooks, P. B. Berger, V. Bittner, B. J. Gersh, et al. “Outcomes of patients with chronic renal insufficiency in the bypass angioplasty revascularization investigation.” Circulation 105, no. 19 (May 14, 2002): 2253–58. https://doi.org/10.1161/01.cir.0000016051.33225.33.
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• Allen LaPointe, Nancy M., Judith M. Kramer, Elizabeth R. DeLong, Truls Ostbye, Bradley G. Hammill, Lawrence H. Muhlbaier, Charles B. McCants, Anita Chen, and Robert M. Califf. “Patient-reported frequency of taking aspirin in a population with coronary artery disease.” The American Journal of Cardiology 89, no. 9 (May 2002): 1042–46. https://doi.org/10.1016/s0002-9149(02)02272-5.
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• Kip, Kevin E., Edwin L. Alderman, Martial G. Bourassa, Maria Mori Brooks, Leonard Schwartz, David R. Holmes, Robert M. Califf, Patrick L. Whitlow, Bernard R. Chaitman, and Katherine M. Detre. “Differential influence of diabetes mellitus on increased jeopardized myocardium after initial angioplasty or bypass surgery: bypass angioplasty revascularization investigation.” Circulation 105, no. 16 (April 23, 2002): 1914–20. https://doi.org/10.1161/01.cir.0000014967.78190.bb.
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• Hypericum  Depression Trial Study Group, M. N. “Effect of Hypericum perforatum (St John's wort) in major depressive disorder: a randomized controlled trial.” Jama 287, no. 14 (April 10, 2002): 1807–14. https://doi.org/10.1001/jama.287.14.1807.
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• Califf, Robert M. “The coxib story: some lessons and more questions.” The American Journal of Cardiology 89, no. 8 (April 2002): 971–72. https://doi.org/10.1016/s0002-9149(02)02249-x.
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• Cuffe, Michael S., Robert M. Califf, Kirkwood F. Adams, Raymond Benza, Robert Bourge, Wilson S. Colucci, Barry M. Massie, et al. “Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial.” Jama 287, no. 12 (March 27, 2002): 1541–47. https://doi.org/10.1001/jama.287.12.1541.
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• Starke, Peter R., and Badrul A. Chowdhury. “Efficacy of intranasal corticosteroids for acute sinusitis.” Jama 287, no. 10 (March 13, 2002): 1261–62. https://doi.org/10.1001/jama.287.10.1261.
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• Califf, Robert M., Elizabeth R. DeLong, Truls Ostbye, Lawrence H. Muhlbaier, Anita Chen, Nancy Allen LaPointe, Bradley G. Hammill, Charles B. McCants, and Judith M. Kramer. “Underuse of aspirin in a referral population with documented coronary artery disease.” The American Journal of Cardiology 89, no. 6 (March 2002): 653–61. https://doi.org/10.1016/s0002-9149(01)02335-9.
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• O’Shea, J Conor, Christopher E. Buller, Warren J. Cantor, A Bleakley Chandler, Eric A. Cohen, David J. Cohen, Ian C. Gilchrist, et al. “Long-term efficacy of platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention.” Jama 287, no. 5 (February 6, 2002): 618–21. https://doi.org/10.1001/jama.287.5.618.
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• Califf, Robert M. “Publication policy, informed consent, and the randomized clinical trial.” Am Heart J 143, no. 2 (February 2002): 187–88. https://doi.org/10.1067/mhj.2002.120406.
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• Gibler, W Brian, Paul W. Armstrong, E Magnus Ohman, W Douglas Weaver, Amanda L. Stebbins, Joel M. Gore, L Kristin Newby, Robert M. Califf, Eric J. Topol, and Eric J. Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) Investigators. “Persistence of delays in presentation and treatment for patients with acute myocardial infarction: The GUSTO-I and GUSTO-III experience.” Ann Emerg Med 39, no. 2 (February 2002): 123–30. https://doi.org/10.1067/mem.2002.121402.
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• Roe, M. T., R. P. Giugliano, R. A. Harrington, C. M. Gibson, J. Strony, M. M. Kitt, R. M. Califf, and E. Braunwald. “Combination reperfusion therapy with eptifibatide and tenecteplase for acute myocardial infarction: Design and methodology of the INTEGRITI (Integrilin and Tenecteplase for Acute Myocardial Infarction) Trial.” Heartdrug 1, no. 1 (December 1, 2001): 5–13. https://doi.org/10.1159/000022704.
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• Shah, M. R., V. Hasselblad, M. Gheorghiade, K. F. Adams, K. Swedberg, R. M. Califf, and C. M. O’Connor. “Prognostic usefulness of the six-minute walk in patients with advanced congestive heart failure secondary to ischemic or nonischemic cardiomyopathy.” The American Journal of Cardiology 88, no. 9 (November 2001): 987–93. https://doi.org/10.1016/s0002-9149(01)01975-0.
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• Anderson, K. M., R. M. Califf, G. W. Stone, F. J. Neumann, G. Montalescot, D. P. Miller, J. J. Ferguson, J. T. Willerson, H. F. Weisman, and E. J. Topol. “Long-term mortality benefit with abciximab in patients undergoing percutaneous coronary intervention.” Journal of the American College of Cardiology 37, no. 8 (June 2001): 2059–65. https://doi.org/10.1016/s0735-1097(01)01290-6.
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• Akkerhuis, K. M., J. W. Deckers, E. Boersma, R. A. Harrington, J. Stepinska, K. W. Mahaffey, R. G. Wilcox, et al. “Geographic variability in outcomes within an international trial of glycoprotein IIb/IIIa inhibition in patients with acute coronary syndromes. Results from PURSUIT.” European Heart Journal 21, no. 5 (March 2000): 371–81. https://doi.org/10.1053/euhj.1999.1743.
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• Batchelor, W. B., C. B. Granger, N. S. Kleiman, H. R. Phillips, S. G. Ellis, A. Betriu, D. A. Criger, et al. “A comparison of ionic versus nonionic contrast medium during primary percutaneous transluminal coronary angioplasty for acute myocardial infarction (GUSTO IIb). Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes.” The American Journal of Cardiology 85, no. 6 (March 2000): 692–97. https://doi.org/10.1016/s0002-9149(99)00842-5.
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• Brener, S. J., S. G. Ellis, S. K. Sapp, A. Betriu, C. B. Granger, J. E. Burchenal, D. J. Moliterno, R. M. Califf, and E. J. Topol. “Predictors of death and reinfarction at 30 days after primary angioplasty: the GUSTO IIb and RAPPORT trials.” American Heart Journal 139, no. 3 (March 2000): 476–81. https://doi.org/10.1016/s0002-8703(00)90091-7.
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• Christenson, R. H., R. T. Vollmer, E. M. Ohman, S. Peck, T. D. Thompson, S. H. Duh, S. G. Ellis, L. K. Newby, E. J. Topol, and R. M. Califf. “Relation of temporal creatine kinase-MB release and outcome after thrombolytic therapy for acute myocardial infarction. TAMI Study Group.” The American Journal of Cardiology 85, no. 5 (March 2000): 543–47. https://doi.org/10.1016/s0002-9149(99)00808-5.
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• Eisenstein, E. L., E. D. Peterson, J. G. Jollis, B. E. Tardiff, R. M. Califf, J. D. Knight, and D. B. Mark. “Evaluating the potential 'economic attractiveness' of new therapies in patients with non-ST elevation acute coronary syndrome.” Pharmacoeconomics 17, no. 3 (March 2000): 263–72. https://doi.org/10.2165/00019053-200017030-00004.
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• Hasdai, D., D. R. Holmes, D. A. Criger, E. J. Topol, R. M. Califf, R. G. Wilcox, E. Paolasso, M. Simoons, J. Deckers, and R. A. Harrington. “Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators.” American Heart Journal 139, no. 3 (March 2000): 454–60. https://doi.org/10.1016/s0002-8703(00)90089-9.
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• Shah, A., G. S. Wagner, C. B. Granger, C. M. O’Connor, C. L. Green, K. M. Trollinger, R. M. Califf, and M. W. Krucoff. “Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment.” J Am Coll Cardiol 35, no. 3 (March 1, 2000): 666–72. https://doi.org/10.1016/s0735-1097(99)00601-4.
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• Califf, R. M. “Combination therapy for acute myocardial infarction: Fibrinolytic therapy and glycoprotein IIb/IIIa inhibition.” American Heart Journal 139, no. 2 II (February 23, 2000).
• Kleiman, N. S., A. M. Lincoff, G. C. Flaker, K. S. Pieper, R. G. Wilcox, L. G. Berdan, T. J. Lorenz, et al. “Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes. PURSUIT Investigators.” Circulation 101, no. 7 (February 22, 2000): 751–57. https://doi.org/10.1161/01.cir.101.7.751.
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• Auerbach, A. D., M. B. Hamel, R. B. Davis, A. F. Connors, C. Regueiro, N. Desbiens, L. Goldman, et al. “Resource use and survival of patients hospitalized with congestive heart failure: differences in care by specialty of the attending physician. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.” Ann Intern Med 132, no. 3 (February 1, 2000): 191–200. https://doi.org/10.7326/0003-4819-132-3-200002010-00004.
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• Califf, R. M. “Combination therapy for acute myocardial infarction: fibrinolytic therapy and glycoprotein IIb/IIIa inhibition.” Am Heart J 139, no. 2 Pt 2 (February 2000): S33–37. https://doi.org/10.1067/mhj.2000.104090.
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• Mark, D. B., R. A. Harrington, A. M. Lincoff, R. M. Califf, C. L. Nelson, A. A. Tsiatis, H. Buell, K. W. Mahaffey, L. Davidson-Ray, and E. J. Topol. “Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes.” Circulation 101, no. 4 (February 1, 2000): 366–71. https://doi.org/10.1161/01.cir.101.4.366.
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• Thel, M. C., R. M. Califf, B. E. Tardiff, L. H. Gardner, K. N. Sigmon, A. M. Lincoff, E. J. Topol, M. M. Kitt, J. C. Blankenship, and J. E. Tcheng. “Timing of and risk factors for myocardial ischemic events after percutaneous coronary intervention (IMPACT-II). Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis.” The American Journal of Cardiology 85, no. 4 (February 2000): 427–34. https://doi.org/10.1016/s0002-9149(99)00767-5.
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• Alexander, J. H., R. A. Sparapani, K. W. Mahaffey, J. W. Deckers, L. K. Newby, E. M. Ohman, R. Corbalán, et al. “Association between minor elevations of creatine kinase-MB level and mortality in patients with acute coronary syndromes without ST-segment elevation. PURSUIT Steering Committee. Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy.” Jama 283, no. 3 (January 19, 2000): 347–53. https://doi.org/10.1001/jama.283.3.347.
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• Crenshaw, B. S., C. B. Granger, Y. Birnbaum, K. S. Pieper, D. C. Morris, N. S. Kleiman, A. Vahanian, R. M. Califf, and E. J. Topol. “Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO-I (Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators.” Circulation 101, no. 1 (January 4, 2000): 27–32. https://doi.org/10.1161/01.cir.101.1.27.
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• Braunwald, E., R. M. Califf, C. P. Cannon, K. A. Fox, V. Fuster, W. B. Gibler, R. A. Harrington, et al. “Redefining medical treatment in the management of unstable angina.” The American Journal of Medicine 108, no. 1 (January 2000): 41–53. https://doi.org/10.1016/s0002-9343(99)00416-7.
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• Califf, R. M., and J. N. Cohn. “Cardiac protection: evolving role of angiotensin receptor blockers.” Am Heart J 139, no. 1 Pt 2 (January 2000): S15–22. https://doi.org/10.1067/mhj.2000.102903.
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• Califf, R. “How should phase II trials in cardiovascular medicine be conducted?” American Heart Journal 139, no. 4 (2000): S131–32.
• Cuffe, M. S., R. M. Califf, K. F. Adams, R. C. Bourge, W. Colucci, B. Massie, C. M. O’Connor, et al. “Rationale and design of the OPTIME CHF trial: outcomes of a prospective trial of intravenous milrinone for exacerbations of chronic heart failure.” American Heart Journal 139, no. 1 Pt 1 (January 2000): 15–22. https://doi.org/10.1016/s0002-8703(00)90303-x.
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• Hasdai, D., R. M. Califf, T. D. Thompson, J. S. Hochman, E. M. Ohman, M. Pfisterer, E. R. Bates, et al. “Predictors of cardiogenic shock after thrombolytic therapy for acute myocardial infarction.” J Am Coll Cardiol 35, no. 1 (January 2000): 136–43. https://doi.org/10.1016/s0735-1097(99)00508-2.
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• Kleiman, N. S., R. P. Tracy, J. D. Talley, K. Sigmon, D. Joseph, E. J. Topol, R. M. Califf, M. Kitt, and E. M. Ohman. “Inhibition of platelet aggregation with a glycoprotein IIb-IIIa antagonist does not prevent thrombin generation in patients undergoing thrombolysis for acute myocardial infarction.” J Thromb Thrombolysis 9, no. 1 (January 2000): 5–12. https://doi.org/10.1023/a:1018650123272.
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• Phillips, R. S., M. B. Hamel, J. M. Teno, J. Soukup, J. Lynn, R. Califf, H. Vidaillet, R. B. Davis, P. Bellamy, and L. Goldman. “Patient race and decisions to withhold or withdraw life-sustaining treatments for seriously ill hospitalized adults. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.” The American Journal of Medicine 108, no. 1 (January 2000): 14–19. https://doi.org/10.1016/s0002-9343(99)00312-5.
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• Wenger, N. S., R. S. Phillips, J. M. Teno, R. K. Oye, N. V. Dawson, H. Liu, R. Califf, P. Layde, R. Hakim, and J. Lynn. “Physician understanding of patient resuscitation preferences: Insights and clinical implications.” Journal of the American Geriatrics Society 48, no. 5 SUPPL. (2000): S44–51.
• Ohman, E. M., P. W. Armstrong, H. D. White, C. B. Granger, R. G. Wilcox, W. D. Weaver, W. B. Gibler, et al. “Risk stratification with a point-of-care cardiac troponin T test in acute myocardial infarction. GUSTOIII Investigators. Global Use of Strategies To Open Occluded Coronary Arteries.” Am J Cardiol 84, no. 11 (December 1, 1999): 1281–86. https://doi.org/10.1016/s0002-9149(99)00558-5.
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• Topol, E. J., D. B. Mark, A. M. Lincoff, E. Cohen, J. Burton, N. Kleiman, D. Talley, et al. “Outcomes at 1 year and economic implications of platelet glycoprotein IIb/IIIa blockade in patients undergoing coronary stenting: results from a multicentre randomised trial. EPISTENT Investigators. Evaluation of Platelet IIb/IIIa Inhibitor for Stenting.” Lancet (London, England) 354, no. 9195 (December 1999): 2019–24. https://doi.org/10.1016/s0140-6736(99)10018-7.
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• Boersma, E., K. M. Akkerhuis, P. Théroux, R. M. Califf, E. J. Topol, and M. L. Simoons. “Platelet glycoprotein IIb/IIIa receptor inhibition in non-ST-elevation acute coronary syndromes: early benefit during medical treatment only, with additional protection during percutaneous coronary intervention.” Circulation 100, no. 20 (November 16, 1999): 2045–48. https://doi.org/10.1161/01.cir.100.20.2045.
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• Holmes, D. R., P. B. Berger, J. S. Hochman, C. B. Granger, T. D. Thompson, R. M. Califf, A. Vahanian, E. R. Bates, and E. J. Topol. “Cardiogenic shock in patients with acute ischemic syndromes with and without ST-segment elevation.” Circulation 100, no. 20 (November 16, 1999): 2067–73. https://doi.org/10.1161/01.cir.100.20.2067.
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• Kong, D. F., E. J. Topol, J. A. Bittl, H. D. White, P. Théroux, V. Hasselblad, and R. M. Califf. “Clinical outcomes of bivalirudin for ischemic heart disease.” Circulation 100, no. 20 (November 16, 1999): 2049–53. https://doi.org/10.1161/01.cir.100.20.2049.
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• Cohen, M. G., C. B. Granger, E. M. Ohman, A. L. Stebbins, L. R. Grinfeld, A. M. Cagide, M. V. Elizari, et al. “Outcome of Hispanic patients treated with thrombolytic therapy for acute myocardial infarction: results from the GUSTO-I and III trials. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.” J Am Coll Cardiol 34, no. 6 (November 15, 1999): 1729–37. https://doi.org/10.1016/s0735-1097(99)00433-7.
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• Mahaffey, K. W., J. A. Puma, N. A. Barbagelata, M. F. DiCarli, M. A. Leesar, K. F. Browne, P. R. Eisenberg, et al. “Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trial.” J Am Coll Cardiol 34, no. 6 (November 15, 1999): 1711–20. https://doi.org/10.1016/s0735-1097(99)00418-0.
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• Gilchrist, I. C., L. H. Gardner, J. B. Muhlestein, A. M. Arnold, A. M. Lincoff, R. M. Califf, J. E. Tcheng, and E. J. Topol. “Effect of institutional volume and academic status on outcomes of coronary interventions: the IMPACT-II experience.” Am Heart J 138, no. 5 Pt 1 (November 1999): 976–82. https://doi.org/10.1016/s0002-8703(99)70026-8.
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• Gilchrist, I. C., L. H. Gardner, J. B. Muhlestein, A. M. Arnold, A. M. Lincoff, R. M. Califf, J. E. Tcheng, and E. J. Topol. “Effect of institutional volume and academic status on outcomes of coronary interventions: the IMPACT-II experience.” American Heart Journal 138, no. 5 Pt 1 (November 1999): 976–82. https://doi.org/10.1016/s0002-8703(99)70026-8.
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• McGuire, D. K., and R. M. Califf. “Diabetes and cardiovascular disease: current opinions and future directions.” American Heart Journal 138, no. 5 Pt 1 (November 1999): S327–29. https://doi.org/10.1016/s0002-8703(99)70030-x.
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• Whitlow, P. L., A. P. Dimas, T. M. Bashore, R. M. Califf, M. G. Bourassa, B. R. Chaitman, A. D. Rosen, K. E. Kip, M. L. Stadius, and E. L. Alderman. “Relationship of extent of revascularization with angina at one year in the Bypass Angioplasty Revascularization Investigation (BARI).” Journal of the American College of Cardiology 34, no. 6 (November 1999): 1750–59. https://doi.org/10.1016/s0735-1097(99)00406-4.
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• Kong, D. F., and R. M. Califf. “Glycoprotein IIb/IIIa receptor antagonists in non-ST elevation acute coronary syndromes and percutaneous revascularisation: a review of trial reports.” Drugs 58, no. 4 (October 1999): 609–20. https://doi.org/10.2165/00003495-199958040-00003.
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• Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada. The CARS Investigators (Coumadin/Aspirin Reinfarction Study).” Can J Cardiol 15, no. 10 (October 1999): 1095–1102.
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• Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada.” Canadian Journal of Cardiology 15, no. 10 (October 1, 1999): 1095–1102.
• Miller, J. M., R. Smalling, E. M. Ohman, C. Bode, A. Betriu, N. S. Kleiman, J. S. Schildcrout, E. Bastos, E. J. Topol, and R. M. Califf. “Effectiveness of early coronary angioplasty and abciximab for failed thrombolysis (reteplase or alteplase) during acute myocardial infarction (results from the GUSTO-III trial). Global Use of Strategies To Open occluded coronary arteries.” The American Journal of Cardiology 84, no. 7 (October 1999): 779–84. https://doi.org/10.1016/s0002-9149(99)00437-3.
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• Mahaffey, K. W., C. B. Granger, M. A. Sloan, C. L. Green, J. M. Gore, W. D. Weaver, H. D. White, et al. “Neurosurgical evacuation of intracranial hemorrhage after thrombolytic therapy for acute myocardial infarction: experience from the GUSTO-I trial. Global Utilization of Streptokinase and tissue-plasminogen activator (tPA) for Occluded Coronary Arteries.” Am Heart J 138, no. 3 Pt 1 (September 1999): 493–99. https://doi.org/10.1016/s0002-8703(99)70152-3.
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• Ryan, T. J., E. M. Antman, N. H. Brooks, R. M. Califf, L. D. Hillis, L. F. Hiratzka, E. Rapaport, et al. “1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).” Journal of the American College of Cardiology 34, no. 3 (September 1999): 890–911. https://doi.org/10.1016/s0735-1097(99)00351-4.
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• Ryan, T. J., E. M. Antman, N. H. Brooks, R. M. Califf, L. D. Hillis, L. F. Hiratzka, E. Rapaport, et al. “1999 update: ACC/AHA Guidelines for the Management of Patients With Acute Myocardial Infarction: Executive Summary and Recommendations: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).” Circulation 100, no. 9 (August 31, 1999): 1016–30. https://doi.org/10.1161/01.cir.100.9.1016.
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• Assessment of the Safety and Efficacy of a New Thrombolytic (ASSENT-2) Investigators, H., F. Van De Werf, J. Adgey, D. Ardissino, P. W. Armstrong, P. Aylward, G. Barbash, et al. “Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial.” Lancet 354, no. 9180 (August 28, 1999): 716–22. https://doi.org/10.1016/s0140-6736(99)07403-6.
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• Bart, B. A., G. Ertl, P. Held, J. Kuch, A. P. Maggioni, J. McMurray, E. L. Michelson, et al. “Contemporary management of patients with left ventricular systolic dysfunction. Results from the Study of Patients Intolerant of Converting Enzyme Inhibitors (SPICE) Registry.” European Heart Journal 20, no. 16 (August 1999): 1182–90. https://doi.org/10.1053/euhj.1998.1481.
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• Simoons, M. L., M. van den Brand, M. Lincoff, R. Harrington, R. van der Wieken, A. Vahanian, W. Rutsch, et al. “Minimal myocardial damage during coronary intervention is associated with impaired outcome.” European Heart Journal 20, no. 15 (August 1999): 1112–19. https://doi.org/10.1053/euhj.1999.1521.
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• Lincoff, A. M., R. M. Califf, D. J. Moliterno, S. G. Ellis, J. Ducas, J. H. Kramer, N. S. Kleiman, et al. “Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators.” N Engl J Med 341, no. 5 (July 29, 1999): 319–27. https://doi.org/10.1056/NEJM199907293410503.
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• Hochman, J. S., J. E. Tamis, T. D. Thompson, W. D. Weaver, H. D. White, F. Van de Werf, P. Aylward, E. J. Topol, and R. M. Califf. “Sex, clinical presentation, and outcome in patients with acute coronary syndromes. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes IIb Investigators.” N Engl J Med 341, no. 4 (July 22, 1999): 226–32. https://doi.org/10.1056/NEJM199907223410402.
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• Berger, P. B., S. G. Ellis, D. R. Holmes, C. B. Granger, D. A. Criger, A. Betriu, E. J. Topol, and R. M. Califf. “Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the global use of strategies to open occluded arteries in Acute Coronary Syndromes (GUSTO-IIb) trial.” Circulation 100, no. 1 (July 6, 1999): 14–20. https://doi.org/10.1161/01.cir.100.1.14.
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• Batchelor, W. B., E. D. Peterson, D. B. Mark, J. D. Knight, C. B. Granger, P. W. Armstrong, and R. M. Califf. “A comparison of U.S. and Canadian cardiac catheterization practices in detecting severe coronary artery disease after myocardial infarction: efficiency, yield and long-term implications.” Journal of the American College of Cardiology 34, no. 1 (July 1999): 12–19. https://doi.org/10.1016/s0735-1097(99)00174-6.
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• Califf, R. M. “Glycoprotein IIb/IIIa blockade and thrombolytics: early lessons from the SPEED and GUSTO IV trials.” Am Heart J 138, no. 1 Pt 2 (July 1999): S12–15. https://doi.org/10.1053/hj.1999.v138.99235.
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• Hasdai, D., D. R. Holmes, R. M. Califf, T. D. Thompson, J. S. Hochman, M. Pfisterer, and E. J. Topol. “Cardiogenic shock complicating acute myocardial infarction: predictors of death. GUSTO Investigators. Global Utilization of Streptokinase and Tissue-Plasminogen Activator for Occluded Coronary Arteries.” Am Heart J 138, no. 1 Pt 1 (July 1999): 21–31. https://doi.org/10.1016/s0002-8703(99)70241-3.
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• O’Connor, C. M., W. A. Gattis, B. F. Uretsky, K. F. Adams, S. E. McNulty, S. H. Grossman, W. J. McKenna, et al. “Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST).” Am Heart J 138, no. 1 Pt 1 (July 1999): 78–86. https://doi.org/10.1016/s0002-8703(99)70250-4.
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• McClure, M. W., S. D. Berkowitz, R. Sparapani, R. Tuttle, N. S. Kleiman, L. G. Berdan, A. M. Lincoff, et al. “Clinical significance of thrombocytopenia during a non-ST-elevation acute coronary syndrome. The platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial experience.” Circulation 99, no. 22 (June 8, 1999): 2892–2900. https://doi.org/10.1161/01.cir.99.22.2892.
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• Kong, D. F., and R. M. Califf. “Coronary interventions "to go": Is faster better?” J Invasive Cardiol 11, no. 6 (June 1999): 401–2.
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• Mahaffey, K. W., R. A. Harrington, M. L. Simoons, C. B. Granger, C. Graffagnino, M. J. Alberts, D. T. Laskowitz, et al. “Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators.” Circulation 99, no. 18 (May 11, 1999): 2371–77. https://doi.org/10.1161/01.cir.99.18.2371.
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• Alexander, J. H., C. B. Granger, Z. Sadowski, P. E. Aylward, H. D. White, T. D. Thompson, R. M. Califf, and E. J. Topol. “Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators.” American Heart Journal 137, no. 5 (May 1999): 799–805. https://doi.org/10.1016/s0002-8703(99)70402-3.
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• Califf, R. M. “Economics and cost-effectiveness in evaluating the value of cardiovascular therapies. Evaluating the economic implications of cardiovascular therapeutics.” American Heart Journal 137, no. 5 (May 1999): S35–37. https://doi.org/10.1016/s0002-8703(99)70425-4.
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• Califf, R. M., D. Stump, E. J. Topol, and D. B. Mark. “Economic and cost-effectiveness in evaluating the value of cardiovascular therapies. The impact of the cost-effectiveness study of GUSTO-1 on decision making with regard to fibrinolytic therapy.” Am Heart J 137, no. 5 (May 1999): S90–93. https://doi.org/10.1016/s0002-8703(99)70438-2.
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• Califf, R. M., D. Stump, E. J. Topol, and D. B. Mark. “Economic and cost-effectiveness in evaluating the value of cardiovascular therapies. The impact of the cost-effectiveness study of GUSTO-1 on decision making with regard to fibrinolytic therapy.” American Heart Journal 137, no. 5 (May 1999): S90–93. https://doi.org/10.1016/s0002-8703(99)70438-2.
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• Lincoff, A. M., J. E. Tcheng, R. M. Califf, D. J. Kereiakes, T. A. Kelly, G. C. Timmis, N. S. Kleiman, et al. “Sustained suppression of ischemic complications of coronary intervention by platelet GP IIb/IIIa blockade with abciximab: one-year outcome in the EPILOG trial. Evaluation in PTCA to Improve Long-term Outcome with abciximab GP IIb/IIIa blockade.” Circulation 99, no. 15 (April 20, 1999): 1951–58. https://doi.org/10.1161/01.cir.99.15.1951.
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• Adams, K. F., C. A. Sueta, M. Gheorghiade, C. M. O’Connor, T. A. Schwartz, G. G. Koch, B. Uretsky, et al. “Gender differences in survival in advanced heart failure. Insights from the FIRST study.” Circulation 99, no. 14 (April 13, 1999): 1816–21. https://doi.org/10.1161/01.cir.99.14.1816.
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• Alexander, J. H., R. A. Harrington, R. H. Tuttle, L. G. Berdan, A. M. Lincoff, J. W. Deckers, M. L. Simoons, et al. “Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes. PURSUIT Investigators. Platelet IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy.” The American Journal of Cardiology 83, no. 8 (April 1999): 1147–51. https://doi.org/10.1016/s0002-9149(99)00049-1.
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• Califf, R. M. “What to do with acute atrial fibrillation?” American Heart Journal 137, no. 4 Pt 1 (April 1999): 601–2. https://doi.org/10.1016/s0002-8703(99)70211-5.
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• Hasdai, D., A. Lerman, C. S. Rihal, D. A. Criger, K. N. Garratt, A. Betriu, H. D. White, et al. “Smoking status and outcome after primary coronary angioplasty for acute myocardial infarction.” American Heart Journal 137, no. 4 Pt 1 (April 1999): 612–20. https://doi.org/10.1016/s0002-8703(99)70213-9.
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• Narins, C. R., D. P. Miller, R. M. Califf, and E. J. Topol. “The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization: insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications.” Journal of the American College of Cardiology 33, no. 3 (March 1999): 647–53. https://doi.org/10.1016/s0735-1097(98)00620-2.
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• O’Connor, C. M., W. A. Gattis, F. Zannad, S. E. McNulty, M. Gheorghiade, K. F. Adams, R. M. Califf, W. J. McKenna, J. Soler-Soler, and K. Swedberg. “Beta-blocker therapy in advanced heart failure: clinical characteristics and long-term outcomes.” Eur J Heart Fail 1, no. 1 (March 1999): 81–88. https://doi.org/10.1016/S1388-9842(98)00004-X.
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• Savonitto, S., D. Ardissino, C. B. Granger, G. Morando, M. D. Prando, A. Mafrici, C. Cavallini, et al. “Prognostic value of the admission electrocardiogram in acute coronary syndromes.” Jama 281, no. 8 (February 24, 1999): 707–13. https://doi.org/10.1001/jama.281.8.707.
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• Berger, P. B., R. H. Tuttle, D. R. Holmes, E. J. Topol, P. E. Aylward, J. H. Horgan, and R. M. Califf. “One-year survival among patients with acute myocardial infarction complicated by cardiogenic shock, and its relation to early revascularization: results from the GUSTO-I trial.” Circulation 99, no. 7 (February 23, 1999): 873–78. https://doi.org/10.1161/01.cir.99.7.873.
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• Puma, J. A., M. H. Sketch, T. D. Thompson, R. J. Simes, D. C. Morris, H. D. White, E. J. Topol, and R. M. Califf. “Support for the open-artery hypothesis in survivors of acute myocardial infarction: analysis of 11,228 patients treated with thrombolytic therapy.” Am J Cardiol 83, no. 4 (February 15, 1999): 482–87. https://doi.org/10.1016/s0002-9149(98)00899-6.
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• Detre, K. M., P. Guo, R. Holubkov, R. M. Califf, G. Sopko, R. Bach, M. M. Brooks, et al. “Coronary revascularization in diabetic patients: a comparison of the randomized and observational components of the Aypass Angioplasty Revascularization Investigation (BARI).” Circulation 99, no. 5 (February 9, 1999): 633–40. https://doi.org/10.1161/01.cir.99.5.633.
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• Harrington, R. A., R. M. Califf, D. R. Holmes, K. S. Pieper, A. M. Lincoff, L. G. Berdan, T. D. Thompson, and E. J. Topol. “Is all unstable angina the same? insights from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT-I). The CAVEAT-Investigators.” Am Heart J 137, no. 2 (February 1999): 227–33. https://doi.org/10.1053/hj.1999.v137.90600.
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• Holmes, D. R., H. D. White, K. S. Pieper, S. G. Ellis, R. M. Califf, and E. J. Topol. “Effect of age on outcome with primary angioplasty versus thrombolysis.” Journal of the American College of Cardiology 33, no. 2 (February 1999): 412–19. https://doi.org/10.1016/s0735-1097(98)00579-8.
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• Thel, M. C., R. M. Califf, J. E. Tcheng, K. N. Sigmon, A. M. Lincoff, E. J. Topol, and S. G. Ellis. “Clinical risk factors for ischemic complications after percutaneous coronary interventions: results from the EPIC trial. The EPIC Investigators.” Am Heart J 137, no. 2 (February 1999): 264–73. https://doi.org/10.1053/hj.1999.v137.92521.
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• Tung, C. Y., C. B. Granger, M. A. Sloan, E. J. Topol, J. D. Knight, W. D. Weaver, K. W. Mahaffey, et al. “Effects of stroke on medical resource use and costs in acute myocardial infarction. GUSTO I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries Study.” Circulation 99, no. 3 (January 26, 1999): 370–76. https://doi.org/10.1161/01.cir.99.3.370.
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• Reimer, K. A., and R. M. Califf. “Good news for experimental concept but bad news for clinically effective therapy.” Circulation 99, no. 2 (January 19, 1999): 198–200. https://doi.org/10.1161/01.cir.99.2.198.
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• Barbagelata, A., M. F. Di Carli, E. B. Sgarbossa, R. M. Califf, P. Clemmensen, D. A. Criger, K. B. Gates, et al. “The use of tomographic myocardial perfusion scanning to evaluate an electrocardiographic salvage estimation method in patients with acute myocardial infarction: an AMISTAD substudy. Acute Myocardial Infarction Study Adenosine.” Journal of Electrocardiology 32 Suppl (January 1999): 111–13. https://doi.org/10.1016/s0022-0736(99)90059-6.
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• Califf, R. M. “When I have acute coronary syndrome, treat me gingerly.” European Heart Journal, Supplement 1, no. N (January 1, 1999).
• Califf, R. M. “Integrated plan of care.” Cardiology Review 16, no. 10 (January 1, 1999).
• Califf, R. M., and D. B. Mark. “Dealing with success at the American Heart Journal.” American Heart Journal 137, no. 5 (January 1, 1999): 769. https://doi.org/10.1016/S0002-8703(99)70394-7.
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• Dawson, N. V., P. Jaagosild, C. Thomas, N. S. Wenger, J. Tsevat, W. A. Knaus, R. M. Califf, et al. “Quality-of-life outcomes for patients with severe CHF.” Cardiology Review 16, no. 5 (January 1, 1999): 14–21.
• Granger, C. B., and R. M. Califf. “The gusto trials.” Journal of Interventional Cardiology 12, no. 1 (January 1, 1999): 13–31. https://doi.org/10.1111/j.1540-8183.1999.tb00207.x.
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• Hasdai, D., D. R. Holmes, E. J. Topol, P. B. Berger, D. A. Criger, J. S. Hochman, E. R. Bates, et al. “Frequency and clinical outcome of cardiogenic shock during acute myocardial infarction among patients receiving reteplase or alteplase. Results from GUSTO-III. Global Use of Strategies to Open Occluded Coronary Arteries.” European Heart Journal 20, no. 2 (January 1999): 128–35. https://doi.org/10.1053/euhj.1999.1282.
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• Kleiman, N. S., C. B. Granger, H. D. White, P. Armstrong, D. Ardissino, F. V. de Werf, P. Zoldeyhi, T. D. Thompson, R. M. Califf, and E. J. Topol. “Death and nonfatal reinfarction within the first 24 hours after presentation with an acute coronary syndrome: experience from GUSTO-IIb. Global Utilization of Strategies for Total Occlusion.” American Heart Journal 137, no. 1 (January 1999): 12–23. https://doi.org/10.1016/s0002-8703(99)70455-2.
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• Tardiff, B. E., R. M. Califf, J. E. Tcheng, A. M. Lincoff, K. N. Sigmon, R. A. Harrington, K. W. Mahaffey, et al. “Clinical outcomes after detection of elevated cardiac enzymes in patients undergoing percutaneous intervention. IMPACT-II Investigators. Integrilin (eptifibatide) to Minimize Platelet Aggregation and Coronary Thrombosis-II.” J Am Coll Cardiol 33, no. 1 (January 1999): 88–96. https://doi.org/10.1016/s0735-1097(98)00551-8.
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• Kong, D. F., R. M. Califf, D. P. Miller, D. J. Moliterno, H. D. White, R. A. Harrington, J. E. Tcheng, A. M. Lincoff, V. Hasselblad, and E. J. Topol. “Clinical outcomes of therapeutic agents that block the platelet glycoprotein IIb/IIIa integrin in ischemic heart disease.” Circulation 98, no. 25 (December 22, 1998): 2829–35. https://doi.org/10.1161/01.cir.98.25.2829.
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• Califf, R. M. “Ten years of benefit from a one-hour intervention.” Circulation 98, no. 24 (December 15, 1998): 2649–51. https://doi.org/10.1161/01.cir.98.24.2649.
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• Newby, K. H., T. Thompson, A. Stebbins, E. J. Topol, R. M. Califf, and A. Natale. “Sustained ventricular arrhythmias in patients receiving thrombolytic therapy: incidence and outcomes. The GUSTO Investigators.” Circulation 98, no. 23 (December 8, 1998): 2567–73. https://doi.org/10.1161/01.cir.98.23.2567.
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• Alexander, K. P., E. D. Peterson, C. B. Granger, A. C. Casas, F. Van de Werf, P. W. Armstrong, A. Guerci, E. J. Topol, and R. M. Califf. “Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes trial.” Journal of the American College of Cardiology 32, no. 7 (December 1998): 2023–30. https://doi.org/10.1016/s0735-1097(98)00466-5.
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• Simons, G. R., E. Sgarbossa, G. Wagner, R. M. Califf, E. J. Topol, and A. Natale. “Atrioventricular and intraventricular conduction disorders in acute myocardial infarction: a reappraisal in the thrombolytic era.” Pacing Clin Electrophysiol 21, no. 12 (December 1998): 2651–63. https://doi.org/10.1111/j.1540-8159.1998.tb00042.x.
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• “Combining thrombolysis with the platelet glycoprotein IIb/IIIa inhibitor lamifiban: results of the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) trial.” J Am Coll Cardiol 32, no. 7 (December 1998): 2003–10. https://doi.org/10.1016/s0735-1097(98)00474-4.
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• Califf, RM, and Harrington, RA. "New agents, new trials, new solutions." Journal of Thrombosis and Thrombolysis 5, no. SUPPL. 2 (December 1, 1998).
• Armstrong, P. W., Y. Fu, W. C. Chang, E. J. Topol, C. B. Granger, A. Betriu, F. Van de Werf, K. L. Lee, and R. M. Califf. “Acute coronary syndromes in the GUSTO-IIb trial: prognostic insights and impact of recurrent ischemia. The GUSTO-IIb Investigators.” Circulation 98, no. 18 (November 3, 1998): 1860–68. https://doi.org/10.1161/01.cir.98.18.1860.
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• Newby, L. K., R. H. Christenson, E. M. Ohman, P. W. Armstrong, T. D. Thompson, K. L. Lee, C. W. Hamm, et al. “Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. The GUSTO-IIa Investigators.” Circulation 98, no. 18 (November 3, 1998): 1853–59. https://doi.org/10.1161/01.cir.98.18.1853.
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• Bhatt, D. L., A. M. Lincoff, D. J. Kereiakes, J. E. Tcheng, M. L. Simoons, L. R. van der Wieken, N. Godfrey, R. M. Califf, and E. J. Topol. “Reduction in the need for unplanned stenting with the use of platelet glycoprotein IIb/IIIa blockade in percutaneous coronary intervention.” Am J Cardiol 82, no. 9 (November 1, 1998): 1105-A6. https://doi.org/10.1016/s0002-9149(98)00565-7.
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• Ellis, S. G., A. M. Lincoff, D. Miller, J. E. Tcheng, N. S. Kleiman, D. Kereiakes, R. Califf, and E. J. Topol. “Reduction in complications of angioplasty with abciximab occurs largely independently of baseline lesion morphology. EPIC and EPILOG Investigators. Evaluation of 7E3 for the Prevention of Ischemic Complications. Evaluation of PTCA To Improve Long-term Outcome with abciximab GPIIb/IIIa Receptor Blockade.” Journal of the American College of Cardiology 32, no. 6 (November 1998): 1619–23. https://doi.org/10.1016/s0735-1097(98)00403-3.
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• Zabel, K. M., C. B. Granger, R. C. Becker, E. G. Bovill, J. Hirsh, P. E. Aylward, E. J. Topol, and R. M. Califf. “Use of bedside activated partial thromboplastin time monitor to adjust heparin dosing after thrombolysis for acute myocardial infarction: results of GUSTO-I. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.” American Heart Journal 136, no. 5 (November 1998): 868–76. https://doi.org/10.1016/s0002-8703(98)70133-4.
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• Sloan, M. A., C. A. Sila, K. W. Mahaffey, C. B. Granger, W. T. Longstreth, P. Koudstaal, H. D. White, et al. “Prediction of 30-day mortality among patients with thrombolysis-related intracranial hemorrhage.” Circulation 98, no. 14 (October 6, 1998): 1376–82. https://doi.org/10.1161/01.cir.98.14.1376.
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• Anderson, R. D., E. M. Ohman, D. R. Holmes, R. A. Harrington, G. W. Barsness, N. M. Wildermann, H. R. Phillips, E. J. Topol, and R. M. Califf. “Prognostic value of congestive heart failure history in patients undergoing percutaneous coronary interventions.” Journal of the American College of Cardiology 32, no. 4 (October 1998): 936–41. https://doi.org/10.1016/s0735-1097(98)00339-8.
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• Califf, R. M. “Role and significance of coagulation markers in understanding and treating acute coronary syndromes. Introduction.” American Heart Journal 136, no. 4 Pt 2 Su (October 1998): S1–6. https://doi.org/10.1053/hj.1998.v136.93437.
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• Califf, R. M. “A perspective on the regulation of the evaluation of new antithrombotic drugs.” The American Journal of Cardiology 82, no. 8B (October 1998): 25P-35P. https://doi.org/10.1016/s0002-9149(98)00661-4.
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• Califf, R. M., and R. A. Harrington. “Improved outlook for patients with acute myocardial infarction: an interim progress report.” Eur Heart J 19, no. 10 (October 1998): 1416–18.
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• Califf, R. M. “Robert McKinnon Califf, MD: a conversation with the editor. Interview by William Clifford Roberts.” Am J Cardiol 82, no. 5 (September 1, 1998): 639–58. https://doi.org/10.1016/s0002-9149(98)00482-2.
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• Cohen, M., C. Demers, E. P. Gurfinkel, A. G. Turpie, G. J. Fromell, S. Goodman, A. Langer, et al. “Low-molecular-weight heparins in non-ST-segment elevation ischemia: the ESSENCE trial. Efficacy and Safety of Subcutaneous Enoxaparin versus intravenous unfractionated heparin, in non-Q-wave Coronary Events.” The American Journal of Cardiology 82, no. 5B (September 1998): 19L-24L. https://doi.org/10.1016/s0002-9149(98)00108-8.
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• Lundergan, C. F., J. S. Reiner, W. F. McCarthy, K. S. Coyne, R. M. Califf, and A. M. Ross. “Clinical predictors of early infarct-related artery patency following thrombolytic therapy: importance of body weight, smoking history, infarct-related artery and choice of thrombolytic regimen: the GUSTO-I experience. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries.” Journal of the American College of Cardiology 32, no. 3 (September 1998): 641–47. https://doi.org/10.1016/s0735-1097(98)00278-2.
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• Pfisterer, M., J. L. Cox, C. B. Granger, S. J. Brener, C. D. Naylor, R. M. Califf, F. van de Werf, et al. “Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries.” Journal of the American College of Cardiology 32, no. 3 (September 1998): 634–40. https://doi.org/10.1016/s0735-1097(98)00279-4.
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• Krumholz, H. M., R. S. Phillips, M. B. Hamel, J. M. Teno, P. Bellamy, S. K. Broste, R. M. Califf, et al. “Resuscitation preferences among patients with severe congestive heart failure: results from the SUPPORT project. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.” Circulation 98, no. 7 (August 18, 1998): 648–55. https://doi.org/10.1161/01.cir.98.7.648.
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• Berkowitz, S. D., D. C. Sane, K. N. Sigmon, J. H. Shavender, R. A. Harrington, J. E. Tcheng, E. J. Topol, and R. M. Califf. “Occurrence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularization. Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC) Study Group.” J Am Coll Cardiol 32, no. 2 (August 1998): 311–19. https://doi.org/10.1016/s0735-1097(98)00252-6.
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• Kong, D. F., and R. M. Califf. “Post-procedure heparin: boon or burden?” American Heart Journal 136, no. 2 (August 1998): 183–85. https://doi.org/10.1053/hj.1998.v136.90239.
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• Straznicky, I., H. D. White, C. B. Granger, P. E. Aylward, G. I. Barbash, E. J. Topol, and R. M. Califf. “Effects of four thrombolytic regimens in elderly patients.” Cardiology Review 15, no. 1 (July 13, 1998): 22–28.
• Califf, R. M., H. Vidaillet, and L. Goldman. “Advanced congestive heart failure: What do patients want?” Am Heart J 135, no. 6 Pt 2 Su (June 1998): S320–26. https://doi.org/10.1016/s0002-8703(98)70259-5.
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• Mandak, J. S., J. C. Blankenship, L. H. Gardner, S. D. Berkowitz, F. V. Aguirre, K. N. Sigmon, G. C. Timmis, et al. “Modifiable risk factors for vascular access site complications in the IMPACT II Trial of angioplasty with versus without eptifibatide. Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis.” Journal of the American College of Cardiology 31, no. 7 (June 1998): 1518–24. https://doi.org/10.1016/s0735-1097(98)00130-2.
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• Metz, B. K., H. D. White, C. B. Granger, R. J. Simes, P. W. Armstrong, J. Hirsh, V. Fuster, C. M. MacAulay, R. M. Califf, and E. J. Topol. “Randomized comparison of direct thrombin inhibition versus heparin in conjunction with fibrinolytic therapy for acute myocardial infarction: results from the GUSTO-IIb Trial. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO-IIb) Investigators.” Journal of the American College of Cardiology 31, no. 7 (June 1998): 1493–98. https://doi.org/10.1016/s0735-1097(98)00138-7.
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• Schulman, K. A., D. B. Mark, and R. M. Califf. “Outcomes and costs within a disease management program for advanced congestive heart failure.” Am Heart J 135, no. 6 Pt 2 Su (June 1998): S285–92. https://doi.org/10.1016/s0002-8703(98)70256-x.
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• Jaagosild, P., N. V. Dawson, C. Thomas, N. S. Wenger, J. Tsevat, W. A. Knaus, R. M. Califf, L. Goldman, H. Vidaillet, and A. F. Connors. “Outcomes of acute exacerbation of severe congestive heart failure: quality of life, resource use, and survival. SUPPORT Investigators. The Study to Understand Prognosis and Preferences for Outcomes and Risks of Treatments.” Arch Intern Med 158, no. 10 (May 25, 1998): 1081–89. https://doi.org/10.1001/archinte.158.10.1081.
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• Kleiman, N. S., A. M. Lincoff, D. J. Kereiakes, D. P. Miller, F. V. Aguirre, K. M. Anderson, H. F. Weisman, R. M. Califf, and E. J. Topol. “Diabetes mellitus, glycoprotein IIb/IIIa blockade, and heparin: evidence for a complex interaction in a multicenter trial. EPILOG Investigators.” Circulation 97, no. 19 (May 19, 1998): 1912–20. https://doi.org/10.1161/01.cir.97.19.1912.
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• Mark, D. B., P. A. Cowper, S. D. Berkowitz, L. Davidson-Ray, E. R. DeLong, A. G. Turpie, R. M. Califf, B. Weatherley, and M. Cohen. “Economic assessment of low-molecular-weight heparin (enoxaparin) versus unfractionated heparin in acute coronary syndrome patients: results from the ESSENCE randomized trial. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q wave Coronary Events [unstable angina or non-Q-wave myocardial infarction].” Circulation 97, no. 17 (May 5, 1998): 1702–7. https://doi.org/10.1161/01.cir.97.17.1702.
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• Hochrein, J., F. Sun, K. S. Pieper, K. L. Lee, K. B. Gates, P. W. Armstrong, W. D. Weaver, et al. “Higher T-wave amplitude associated with better prognosis in patients receiving thrombolytic therapy for acute myocardial infarction (a GUSTO-I substudy). Global Utilization of Streptokinase and Tissue plasminogen Activator for Occluded Coronary Arteries.” The American Journal of Cardiology 81, no. 9 (May 1998): 1078–84. https://doi.org/10.1016/s0002-9149(98)00112-x.
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• Califf, R. M., and J. M. Kramer. “What have we learned from the calcium channel blocker controversy?” Circulation 97, no. 16 (April 28, 1998): 1529–31. https://doi.org/10.1161/01.cir.97.16.1529.
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• Ross, A. M., K. S. Coyne, E. Moreyra, J. S. Reiner, S. W. Greenhouse, P. L. Walker, M. L. Simoons, et al. “Extended mortality benefit of early postinfarction reperfusion. GUSTO-I Angiographic Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries Trial.” Circulation 97, no. 16 (April 28, 1998): 1549–56. https://doi.org/10.1161/01.cir.97.16.1549.
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• Braunwald, E., A. Maseri, P. W. Armstrong, R. M. Califf, W. B. Gibler, C. W. Hamm, M. L. Simoons, and F. Van de Werf. “Rationale and clinical evidence for the use of GP IIb/IIIa inhibitors in acute coronary syndromes.” Eur Heart J 19 Suppl D (April 1998): D22–30.
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• Califf, R. M., and C. B. Granger. “Hypertension and diabetes and the Fosinopril versus Amlodipine Cardiovascular Events Trial (FACET). More ammunition against surrogate end points.” Diabetes Care 21, no. 4 (April 1998): 655–57. https://doi.org/10.2337/diacare.21.4.655.
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• Langer, A., M. W. Krucoff, P. Klootwijk, M. L. Simoons, C. B. Granger, A. Barr, R. M. Califf, and P. W. Armstrong. “Prognostic significance of ST segment early after resolution ST elevation in patients with myocardial infarction treated with thrombolytic therapy: The GUSTO-I ST segment monitoring substudy.” Journal of the American College of Cardiology 31, no. 4 (March 15, 1998): 783–89.
• Kereiakes, D. J., A. M. Lincoff, D. P. Miller, J. E. Tcheng, C. F. Cabot, K. M. Anderson, H. F. Weisman, R. M. Califf, and E. J. Topol. “Abciximab therapy and unplanned coronary stent deployment: favorable effects on stent use, clinical outcomes, and bleeding complications. EPILOG Trial Investigators.” Circulation 97, no. 9 (March 10, 1998): 857–64. https://doi.org/10.1161/01.cir.97.9.857.
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• Mahaffey, K. W., C. B. Granger, M. A. Sloan, T. D. Thompson, J. M. Gore, W. D. Weaver, H. D. White, et al. “Risk factors for in-hospital nonhemorrhagic stroke in patients with acute myocardial infarction treated with thrombolysis: results from GUSTO-I.” Circulation 97, no. 8 (March 3, 1998): 757–64. https://doi.org/10.1161/01.cir.97.8.757.
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• Christenson, R. H., S. H. Duh, L. K. Newby, E. M. Ohman, R. M. Califf, C. B. Granger, S. Peck, et al. “Cardiac troponin T and cardiac troponin I: relative values in short-term risk stratification of patients with acute coronary syndromes. GUSTO-IIa Investigators.” Clin Chem 44, no. 3 (March 1998): 494–501.
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• Gebel, J. M., C. A. Sila, M. A. Sloan, C. B. Granger, K. W. Mahaffey, J. Weisenberger, C. L. Green, et al. “Thrombolysis-related intracranial hemorrhage: a radiographic analysis of 244 cases from the GUSTO-1 trial with clinical correlation. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” Stroke 29, no. 3 (March 1998): 563–69. https://doi.org/10.1161/01.str.29.3.563.
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• Granger, C. B., R. Becker, R. P. Tracy, R. M. Califf, E. J. Topol, K. S. Pieper, A. M. Ross, S. Roth, C. Lambrew, and E. G. Bovill. “Thrombin generation, inhibition and clinical outcomes in patients with acute myocardial infarction treated with thrombolytic therapy and heparin: results from the GUSTO-I Trial. GUSTO-I Hemostasis Substudy Group. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.” Journal of the American College of Cardiology 31, no. 3 (March 1998): 497–505. https://doi.org/10.1016/s0735-1097(97)00539-1.
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• Langer, A., M. W. Krucoff, P. Klootwijk, M. L. Simoons, C. B. Granger, A. Barr, R. M. Califf, and P. W. Armstrong. “Prognostic significance of ST segment shift early after resolution of ST elevation in patients with myocardial infarction treated with thrombolytic therapy: the GUSTO-I ST Segment Monitoring Substudy.” Journal of the American College of Cardiology 31, no. 4 (March 1998): 783–89. https://doi.org/10.1016/s0735-1097(97)00544-5.
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• Brophy, J. “Thrombolytic therapy for myocardial infarction.” N Engl J Med 338, no. 8 (February 19, 1998): 545–46.
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• Goodman, S. G., A. Langer, A. M. Ross, N. M. Wildermann, A. Barbagelata, E. B. Sgarbossa, G. S. Wagner, et al. “Non-Q-wave versus Q-wave myocardial infarction after thrombolytic therapy: angiographic and prognostic insights from the global utilization of streptokinase and tissue plasminogen activator for occluded coronary arteries-I angiographic substudy. GUSTO-I Angiographic Investigators.” Circulation 97, no. 5 (February 10, 1998): 444–50. https://doi.org/10.1161/01.cir.97.5.444.
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• Hathaway, W. R., E. D. Peterson, G. S. Wagner, C. B. Granger, K. M. Zabel, K. S. Pieper, K. A. Clark, L. H. Woodlief, and R. M. Califf. “Prognostic significance of the initial electrocardiogram in patients with acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries.” Jama 279, no. 5 (February 4, 1998): 387–91. https://doi.org/10.1001/jama.279.5.387.
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• Brieger, D. B., K. H. Mak, H. D. White, N. S. Kleiman, D. P. Miller, A. Vahanian, A. M. Ross, R. M. Califf, and E. J. Topol. “Benefit of early sustained reperfusion in patients with prior myocardial infarction (the GUSTO-I trial). Global Utilization of Streptokinase and TPA for occluded arteries.” The American Journal of Cardiology 81, no. 3 (February 1998): 282–87. https://doi.org/10.1016/s0002-9149(97)00909-0.
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• Califf, R. M., A. E. Abdelmeguid, R. E. Kuntz, J. J. Popma, C. J. Davidson, E. A. Cohen, N. S. Kleiman, et al. “Myonecrosis after revascularization procedures.” Journal of the American College of Cardiology 31, no. 2 (February 1998): 241–51. https://doi.org/10.1016/s0735-1097(97)00506-8.
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• Hassan, T. B., and D. B. Barnett. “Magnesium in in-hospital cardiac arrest.” Lancet (London, England) 351, no. 9100 (February 1998): 445–46. https://doi.org/10.1016/s0140-6736(05)78390-2.
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• Omoigui, N. A., M. J. Silver, L. A. Rybicki, M. Rosenthal, L. G. Berdan, K. Pieper, S. V. King, R. M. Califf, and E. J. Topol. “Influence of a randomized clinical trial on practice by participating investigators: lessons from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT). CAVEAT I and II Investigators.” Journal of the American College of Cardiology 31, no. 2 (February 1998): 265–72. https://doi.org/10.1016/s0735-1097(97)00498-1.
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• Betriu, A., R. M. Califf, X. Bosch, A. Guerci, A. L. Stebbins, N. A. Barbagelata, P. E. Aylward, A. Vahanian, F. Van de Werf, and E. J. Topol. “Recurrent ischemia after thrombolysis: importance of associated clinical findings. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA [tissue-plasminogen activator] for Occluded Coronary Arteries.” Journal of the American College of Cardiology 31, no. 1 (January 1998): 94–102. https://doi.org/10.1016/s0735-1097(97)00428-2.
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• Blankenship, J. C., A. S. Hellkamp, F. V. Aguirre, S. L. Demko, E. J. Topol, and R. M. Califf. “Vascular access site complications after percutaneous coronary intervention with abciximab in the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC) trial.” The American Journal of Cardiology 81, no. 1 (January 1998): 36–40. https://doi.org/10.1016/s0002-9149(97)00796-0.
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• Califf, R. M., and M. Gheorghiade. “Introduction: Managing the patient with advanced heart failure.” American Heart Journal 135, no. 6 II SUPPL. (January 1, 1998).
• Califf, R. M., and M. L. Simoons. “Introduction: Use of GP IIb/IIIa inhibitors in coronary syndromes: State of the art.” American Heart Journal 135, no. 4 (January 1, 1998).
• Califf, R. M., and M. L. Simoons. “International roundtable on Use of GP IIb/IIIa inhibitors in coronary syndromes: State of the art, Davos, Switzerland, 15-16 February 1997: Foreward.” European Heart Journal 19, no. SUPPL.D (January 1, 1998).
• Ghaffari, S., D. J. Kereiakes, A. M. Lincoff, T. A. Kelly, G. C. Timmis, N. S. Kleiman, J. J. Ferguson, D. P. Miller, R. A. Califf, and E. J. Topol. “Platelet glycoprotein IIb/IIIa receptor blockade with abciximab reduces ischemic complications in patients undergoing directional coronary atherectomy.” American Journal of Cardiology 82, no. 1 (1998): 7–12. https://doi.org/10.1016/S0002-9149(98)00238-0.
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• Khan, M. M., S. G. Ellis, F. V. Aguirre, H. F. Weisman, N. M. Wildermann, R. M. Califf, E. J. Topol, and N. S. Kleiman. “Does intracoronary thrombus influence the outcome of high risk percutaneous transluminal coronary angioplasty? Clinical and angiographic outcomes in a large multicenter trial. EPIC Investigators. Evaluation of IIb/IIIa Platelet Receptor Antagonist 7E3 in Preventing Ischemic Complications.” Journal of the American College of Cardiology 31, no. 1 (January 1998): 31–36. https://doi.org/10.1016/s0735-1097(97)00423-3.
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• Krucoff, M. W., C. L. Green, A. Langer, P. Klootwijk, K. M. Trollinger, J. E. Pope, P. W. Armstrong, M. L. Simoons, E. J. Topol, and R. M. Califf. “Continuous 12-lead ST-segment recovery predicts outcome in acute myocardial infarction better than 'snapshot' angiograms of TIMI flow.” Journal of Electrocardiology 30, no. SUPPL. (January 1, 1998): 167. https://doi.org/10.1016/S0022-0736(98)80069-1.
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• Schulman, K. A., D. B. Mark, and R. M. Califf. “Outcomes and costs within a disease management program for advanced congestive heart failure.” American Heart Journal 135, no. 6 II SUPPL. (January 1, 1998).
• Sgarbossa, E. B., S. L. Pinski, E. J. Topol, R. M. Califf, A. Barbagelata, S. G. Goodman, K. B. Gates, et al. “Acute myocardial infarction and complete bundle branch block at hospital admission: clinical characteristics and outcome in the thrombolytic era. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA [tissue-type plasminogen activator] for Occluded Coronary Arteries.” Journal of the American College of Cardiology 31, no. 1 (January 1998): 105–10. https://doi.org/10.1016/s0735-1097(97)00446-4.
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• Straznicky, Ivan T., John K. French, Harvey D. White, and Robert M. Califf. “Fibrinolysis for Acute Myocardial Infarction in the Elderly Patient: Is it Effective or Too Dangerous?” Am J Geriatr Cardiol 7, no. 1 (January 1998): 22–27.
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• Ohman, E. M., R. M. Califf, E. J. Topol, F. Catella-Lawson, and G. A. FitzGerald. “Trials in myocardial infarction [32] (multiple letters).” Circulation 96, no. 10 (December 12, 1997): 3814–16.
• Califf, R. M. “The GUSTO trial and the open artery theory.” Eur Heart J 18 Suppl F (December 1997): F2-10. https://doi.org/10.1093/eurheartj/18.suppl_f.2.
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• Califf, R. M., S. L. Karnash, and L. H. Woodlief. “Developing systems for cost-effective auditing of clinical trials.” Controlled Clinical Trials 18, no. 6 (December 1997): 651–60. https://doi.org/10.1016/s0197-2456(96)00237-1.
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• Califf, R. M., and D. B. Mark. “Issues of cost-effectiveness in the use of antithrombotic therapy for ischemic heart disease.” American Heart Journal 134, no. 5 II (December 1, 1997).
• Horton, H. L. “Risk stratification after myocardial infarction.” Ann Intern Med 127, no. 11 (December 1, 1997): 1040–41. https://doi.org/10.7326/0003-4819-127-11-199712010-00024.
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• Mahaffey, K. W., C. B. Granger, C. A. Toth, H. D. White, A. L. Stebbins, G. I. Barbash, A. Vahanian, E. J. Topol, and R. M. Califf. “Diabetic retinopathy should not be a contraindication to thrombolytic therapy for acute myocardial infarction: review of ocular hemorrhage incidence and location in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries.” J Am Coll Cardiol 30, no. 7 (December 1997): 1606–10. https://doi.org/10.1016/s0735-1097(97)00394-x.
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• Mahaffey, K. W., C. B. Granger, C. A. Toth, H. D. White, A. L. Stebbins, G. I. Barbash, A. Vahanian, E. J. Topol, and R. M. Califf. “Diabetic retinopathy should not be a contraindication to thrombolytic therapy for acute myocardial infarction: review of ocular hemorrhage incidence and location in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries.” Journal of the American College of Cardiology 30, no. 7 (December 1997): 1606–10. https://doi.org/10.1016/s0735-1097(97)00394-x.
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• Williams, P. A., R. M. Califf, and E. J. Topol. “Tissue-type plasminogen activator's 10% one-year edge.” Cardiology Review 14, no. 2 (December 1, 1997): 41–46.
• Ohman, E. M., R. M. Califf, and E. J. Topol. “Trials in myocardial infarction.” Circulation 96, no. 10 (November 18, 1997): 3814–16.
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• Simon, K., A. Szépvölgyi, and T. Böhm. “Does the early hazard phenomenon exist? Do the GUSTO findings prove or disprove?” Circulation 96, no. 10 (November 18, 1997): 3780–81.
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• Califf, R. M., and D. B. Mark. “Issues of cost-effectiveness in the use of antithrombotic therapy for ischemic heart disease.” Am Heart J 134, no. 5 Pt 2 (November 1997): S88–96.
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• Shah, A., G. S. Wagner, R. M. Califf, R. E. Boineau, C. L. Green, N. M. Wildermann, K. M. Trollinger, J. E. Pope, and M. W. Krucoff. “Comparative prognostic significance of simultaneous versus independent resolution of ST segment depression relative to ST segment elevation during acute myocardial infarction.” Journal of the American College of Cardiology 30, no. 6 (November 1997): 1478–83. https://doi.org/10.1016/s0735-1097(97)00331-8.
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• Thel, M. C., A. L. Armstrong, S. E. McNulty, R. M. Califf, and C. M. O’Connor. “Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff.” Lancet (London, England) 350, no. 9087 (November 1997): 1272–76. https://doi.org/10.1016/s0140-6736(97)05048-4.
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• Barsness, G. W., E. D. Peterson, E. M. Ohman, C. L. Nelson, E. R. DeLong, J. G. Reves, P. K. Smith, et al. “Relationship between diabetes mellitus and long-term survival after coronary bypass and angioplasty.” Circulation 96, no. 8 (October 21, 1997): 2551–56. https://doi.org/10.1161/01.cir.96.8.2551.
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• Mak, K. H., R. Challapalli, M. J. Eisenberg, K. M. Anderson, R. M. Califf, and E. J. Topol. “Effect of platelet glycoprotein IIb/IIIa receptor inhibition on distal embolization during percutaneous revascularization of aortocoronary saphenous vein grafts. EPIC Investigators. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications.” Am J Cardiol 80, no. 8 (October 15, 1997): 985–88. https://doi.org/10.1016/s0002-9149(97)00589-4.
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• Bart, B. A., L. K. Shaw, C. B. McCants, D. F. Fortin, K. L. Lee, R. M. Califf, and C. M. O’Connor. “Clinical determinants of mortality in patients with angiographically diagnosed ischemic or nonischemic cardiomyopathy.” Journal of the American College of Cardiology 30, no. 4 (October 1997): 1002–8. https://doi.org/10.1016/s0735-1097(97)00235-0.
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• Selker, H. P., J. L. Griffith, J. R. Beshansky, C. H. Schmid, R. M. Califf, R. B. D’Agostino, M. M. Laks, et al. “Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument.” Ann Intern Med 127, no. 7 (October 1, 1997): 538–56. https://doi.org/10.7326/0003-4819-127-7-199710010-00006.
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• Christenson, R. H., E. M. Ohman, E. J. Topol, S. Peck, L. K. Newby, S. H. Duh, D. J. Kereiakes, et al. “Assessment of coronary reperfusion after thrombolysis with a model combining myoglobin, creatine kinase-MB, and clinical variables. TAMI-7 Study Group. Thrombolysis and Angioplasty in Myocardial Infarction-7.” Circulation 96, no. 6 (September 16, 1997): 1776–82. https://doi.org/10.1161/01.cir.96.6.1776.
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• Anderson, R. D., E. M. Ohman, D. R. Holmes, I. Col, A. L. Stebbins, E. R. Bates, R. J. Stomel, C. B. Granger, E. J. Topol, and R. M. Califf. “Use of intraaortic balloon counterpulsation in patients presenting with cardiogenic shock: observations from the GUSTO-I Study. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.” Journal of the American College of Cardiology 30, no. 3 (September 1997): 708–15. https://doi.org/10.1016/s0735-1097(97)00227-1.
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• Cohen, M., C. Demers, E. P. Gurfinkel, A. G. Turpie, G. J. Fromell, S. Goodman, A. Langer, et al. “A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group.” N Engl J Med 337, no. 7 (August 14, 1997): 447–52. https://doi.org/10.1056/NEJM199708143370702.
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• Topol, E. J., J. J. Ferguson, H. F. Weisman, J. E. Tcheng, S. G. Ellis, N. S. Kleiman, R. J. Ivanhoe, et al. “Long-term protection from myocardial ischemic events in a randomized trial of brief integrin beta3 blockade with percutaneous coronary intervention. EPIC Investigator Group. Evaluation of Platelet IIb/IIIa Inhibition for Prevention of Ischemic Complication.” Jama 278, no. 6 (August 13, 1997): 479–84. https://doi.org/10.1001/jama.278.6.479.
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• Crenshaw, B. S., S. R. Ward, C. B. Granger, A. L. Stebbins, E. J. Topol, and R. M. Califf. “Atrial fibrillation in the setting of acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.” J Am Coll Cardiol 30, no. 2 (August 1997): 406–13. https://doi.org/10.1016/s0735-1097(97)00194-0.
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• Topol, E. J., J. J. Ferguson, H. F. Weisman, J. E. Tcheng, S. G. Ellis, N. S. Kleiman, R. J. Ivanhoe, et al. “Long-term protection from myocardial ischemic events in a randomized trial of brief integrin beta3 blockade with percutaneous coronary intervention. EPIC Investigator Group. Evaluation of Platelet IIb/IIIa Inhibition for Prevention of Ischemic Complication.” Jama 278, no. 6 (August 1997): 479–84. https://doi.org/10.1001/jama.1997.03550060055036.
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• Berger, P. B., D. R. Holmes, A. L. Stebbins, E. R. Bates, R. M. Califf, and E. J. Topol. “Impact of an aggressive invasive catheterization and revascularization strategy on mortality in patients with cardiogenic shock in the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO-I) trial. An observational study.” Circulation 96, no. 1 (July 1, 1997): 122–27. https://doi.org/10.1161/01.cir.96.1.122.
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• Califf, R. M., K. F. Adams, W. J. McKenna, M. Gheorghiade, B. F. Uretsky, S. E. McNulty, H. Darius, et al. “A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST).” American Heart Journal 134, no. 1 (July 1997): 44–54. https://doi.org/10.1016/s0002-8703(97)70105-4.
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• Lincoff, A. M., R. M. Califf, K. M. Anderson, H. F. Weisman, F. V. Aguirre, N. S. Kleiman, R. A. Harrington, and E. J. Topol. “Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization. EPIC Investigators. Evaluation of 7E3 in Preventing Ischemic Complications.” J Am Coll Cardiol 30, no. 1 (July 1997): 149–56. https://doi.org/10.1016/s0735-1097(97)00110-1.
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• Mak, K. H., D. J. Moliterno, C. B. Granger, D. P. Miller, H. D. White, R. G. Wilcox, R. M. Califf, and E. J. Topol. “Influence of diabetes mellitus on clinical outcome in the thrombolytic era of acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” J Am Coll Cardiol 30, no. 1 (July 1997): 171–79. https://doi.org/10.1016/s0735-1097(97)00118-6.
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• Mattimore, T. J., N. S. Wenger, N. A. Desbiens, J. M. Teno, M. B. Hamel, H. Liu, R. Califf, A. F. Connors, J. Lynn, and R. K. Oye. “Surrogate and physician understanding of patients' preferences for living permanently in a nursing home.” J Am Geriatr Soc 45, no. 7 (July 1997): 818–24. https://doi.org/10.1111/j.1532-5415.1997.tb01508.x.
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• Migrino, R. Q., J. B. Young, S. G. Ellis, H. D. White, C. F. Lundergan, D. P. Miller, C. B. Granger, A. M. Ross, R. M. Califf, and E. J. Topol. “End-systolic volume index at 90 to 180 minutes into reperfusion therapy for acute myocardial infarction is a strong predictor of early and late mortality. The Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I Angiographic Investigators.” Circulation 96, no. 1 (July 1, 1997): 116–21. https://doi.org/10.1161/01.cir.96.1.116.
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• Berkowitz, S. D., C. B. Granger, K. S. Pieper, K. L. Lee, J. M. Gore, M. Simoons, P. W. Armstrong, E. J. Topol, and R. M. Califf. “Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction. The Global Utilization of Streptokinase and Tissue Plasminogen activator for Occluded coronary arteries (GUSTO) I Investigators.” Circulation 95, no. 11 (June 3, 1997): 2508–16. https://doi.org/10.1161/01.cir.95.11.2508.
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• Califf, R. M., L. H. Woodlief, F. E. Harrell, K. L. Lee, H. D. White, A. Guerci, G. I. Barbash, et al. “Selection of thrombolytic therapy for individual patients: development of a clinical model. GUSTO-I Investigators.” American Heart Journal 133, no. 6 (June 1997): 630–39. https://doi.org/10.1016/s0002-8703(97)70164-9.
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• Moen, E. K., C. R. Asher, D. P. Miller, W. D. Weaver, H. D. White, R. M. Califf, and E. J. Topol. “Long-term follow-up of gender-specific outcomes after thrombolytic therapy for acute myocardial infarction from the GUSTO-I trial. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” J Womens Health 6, no. 3 (June 1997): 285–93. https://doi.org/10.1089/jwh.1997.6.285.
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• Tsang, T. S., R. M. Califf, A. L. Stebbins, K. L. Lee, S. Cho, A. M. Ross, and P. W. Armstrong. “Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries.” The American Journal of Cardiology 79, no. 9 (May 1997): 1232–35. https://doi.org/10.1016/s0002-9149(97)00087-8.
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• Eisenberg, M. J., R. M. Califf, E. A. Cohen, A. G. Adelman, D. B. Mark, and E. J. Topol. “Use of evidence-based medical therapy in patients undergoing percutaneous coronary revascularization in the United States, Europe, and Canada. Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT-I) and Canadian Coronary Atherectomy Trial (CCAT) investigators.” The American Journal of Cardiology 79, no. 7 (April 1997): 867–72. https://doi.org/10.1016/s0002-9149(97)00005-2.
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• Puma, J. A., M. H. Sketch, J. E. Tcheng, L. H. Gardner, C. L. Nelson, H. R. Phillips, R. S. Stack, and R. M. Califf. “The natural history of single-vessel chronic coronary occlusion: a 25-year experience.” American Heart Journal 133, no. 4 (April 1997): 393–99. https://doi.org/10.1016/s0002-8703(97)70179-0.
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• Barbagelata, A., R. M. Califf, E. B. Sgarbossa, S. G. Goodman, A. L. Stebbins, C. B. Granger, L. D. Suarez, et al. “Thrombolysis and Q wave versus non-Q wave first acute myocardial infarction: a GUSTO-I substudy. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries Investigators.” Journal of the American College of Cardiology 29, no. 4 (March 1997): 770–77. https://doi.org/10.1016/s0735-1097(96)00587-6.
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• Barbagelata, N. A., C. B. Granger, E. Oqueli, L. D. Suárez, M. Borruel, E. J. Topol, and R. M. Califf. “TIMI grade 3 flow and reocclusion after intravenous thrombolytic therapy: a pooled analysis.” American Heart Journal 133, no. 3 (March 1997): 273–82. https://doi.org/10.1016/s0002-8703(97)70220-5.
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• Califf, R. M., and L. H. Woodlief. “Pragmatic and mechanistic trials.” Eur Heart J 18, no. 3 (March 1997): 367–70. https://doi.org/10.1093/oxfordjournals.eurheartj.a015256.
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• Levine, G. N., A. K. Jacobs, G. P. Keeler, P. L. Whitlow, L. G. Berdan, F. Leya, E. J. Topol, and R. M. Califf. “Impact of diabetes mellitus on percutaneous revascularization (CAVEAT-I). CAVEAT-I Investigators. Coronary Angioplasty Versus Excisional Atherectomy Trial.” The American Journal of Cardiology 79, no. 6 (March 1997): 748–55. https://doi.org/10.1016/s0002-9149(96)00862-4.
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• Talley, J. D., E. M. Ohman, D. B. Mark, B. S. George, J. D. Leimberger, L. G. Berdan, L. Davidson-Ray, et al. “Economic implications of the prophylactic use of intraaortic balloon counterpulsation in the setting of acute myocardial infarction. The Randomized IABP Study Group. Intraaortic Balloon Pump.” Am J Cardiol 79, no. 5 (March 1, 1997): 590–94. https://doi.org/10.1016/0002-9149(96)00821-1.
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• Ward, S. R., J. M. Sutton, K. S. Pieper, M. Schwaiger, R. M. Califf, and E. J. Topol. “Effects of thrombolytic regimen, early catheterization, and predischarge angiographic variables on six-week left ventricular function. The TAMI Investigators. Thrombolysis and Angioplasty in Acute Myocardial Infarction.” The American Journal of Cardiology 79, no. 5 (March 1997): 539–44. https://doi.org/10.1016/s0002-9149(96)00812-0.
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• Ohman, E. M., N. S. Kleiman, G. Gacioch, S. J. Worley, F. I. Navetta, J. D. Talley, H. V. Anderson, et al. “Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. IMPACT-AMI Investigators.” Circulation 95, no. 4 (February 18, 1997): 846–54. https://doi.org/10.1161/01.cir.95.4.846.
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• Topol, E. J., R. M. Califf, F. Van de Werf, M. Simoons, J. Hampton, K. L. Lee, H. White, J. Simes, and P. W. Armstrong. “Perspectives on large-scale cardiovascular clinical trials for the new millennium. The Virtual Coordinating Center for Global Collaborative Cardiovascular Research (VIGOUR) Group.” Circulation 95, no. 4 (February 18, 1997): 1072–82. https://doi.org/10.1161/01.cir.95.4.1072.
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• Peterson, E. D., L. K. Shaw, E. R. DeLong, D. B. Pryor, R. M. Califf, and D. B. Mark. “Racial variation in the use of coronary-revascularization procedures. Are the differences real? Do they matter?” N Engl J Med 336, no. 7 (February 13, 1997): 480–86. https://doi.org/10.1056/NEJM199702133360706.
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• Lincoff, A. M., J. E. Tcheng, R. M. Califf, T. Bass, J. J. Popma, P. S. Teirstein, N. S. Kleiman, et al. “Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization. PROLOG Investigators.” Am J Cardiol 79, no. 3 (February 1, 1997): 286–91. https://doi.org/10.1016/s0002-9149(96)00749-7.
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• Tardiff, B. E., R. M. Califf, D. Morris, E. Bates, L. H. Woodlief, K. L. Lee, C. Green, et al. “Coronary revascularization surgery after myocardial infarction: impact of bypass surgery on survival after thrombolysis. GUSTO Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” Journal of the American College of Cardiology 29, no. 2 (February 1997): 240–49. https://doi.org/10.1016/s0735-1097(96)00492-5.
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• FitzGerald, J. D., N. S. Wenger, R. M. Califf, R. S. Phillips, N. A. Desbiens, H. Liu, J. Lynn, A. W. Wu, A. F. Connors, and R. K. Oye. “Functional status among survivors of in-hospital cardiopulmonary resuscitation.” Archives of Internal Medicine 157, no. 1 (January 21, 1997): 72–76.
• FitzGerald, J. D., N. S. Wenger, R. M. Califf, R. S. Phillips, N. A. Desbiens, H. Liu, J. Lynn, A. W. Wu, A. F. Connors, and R. K. Oye. “Functional status among survivors of in-hospital cardiopulmonary resuscitation. SUPPORT Investigators Study to Understand Progress and Preferences for Outcomes and Risks of Treatment.” Arch Intern Med 157, no. 1 (January 13, 1997): 72–76.
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• Berdan, L. G., N. S. Kleiman, L. H. Woodlief, R. A. Harrington, C. B. Granger, and R. M. Califf. “Physicians' Use of Heparin Following Thrombolytic Therapy: An International Perspective.” J Thromb Thrombolysis 4, no. 3/4 (1997): 415–23. https://doi.org/10.1023/a:1008805601821.
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• Boersma, H., R. Califf, R. Collins, J. W. Deckers, and M. L. Simoons. “Selection of reperfusion therapy for individual patients with evolving myocardial infarction.” European Heart Journal 18, no. 9 (1997): 1371–81.
• Califf, R. M., and D. B. Mark. “Our vision for the American Heart Journal.” Am Heart J 133, no. 1 (January 1997): 137–38. https://doi.org/10.1016/s0002-8703(97)70261-8.
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• Califf, R. M., and D. B. Mark. “Lessons for the editors.” American Heart Journal 134, no. 1 (January 1, 1997): 1–2. https://doi.org/10.1016/S0002-8703(97)70099-1.
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• Califf, R. “Introduction: How will we manage acute coronary syndromes in the new millennium?” American Heart Journal 134, no. 5 II (1997): S53–54.
• Eisenstein, E. L., E. D. Peterson, J. G. Jollis, B. E. Tardiff, R. M. Califf, J. D. Knight, and D. B. Mark. “Assessing the value of newer pharmacologic agents in non-ST elevation patients: a decision support system application.” Proc Amia Annu Fall Symp, 1997, 273–77.
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• Fox, K. A. A., M. Cohen, C. Demers, E. Gurfinkel, G. Fromell, F. Bigonzi, J. Premmereur, et al. “A double blind comparison of enoxaparin (a low molecular weight heparin) with standard heparin in the treatment of unstable coronary artery disease "The essence trial".” Heart 77, no. SUPPL. 1 (1997).
• Holmes, D. R., R. M. Califf, F. Van de Werf, P. B. Berger, E. R. Bates, M. L. Simoons, H. D. White, T. D. Thompson, and E. J. Topol. “Difference in countries' use of resources and clinical outcome for patients with cardiogenic shock after myocardial infarction: results from the GUSTO trial.” Lancet (London, England) 349, no. 9045 (January 1997): 75–78. https://doi.org/10.1016/s0140-6736(96)03031-0.
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• Khan, S. S., J. Forrester, G. Gambassi, R. Landolfi, R. Bernabei, A. M. Lincoff, E. J. Topol, R. M. Califf, and H. D. R. Jr. “Platelet glycoprotein IIb/IIIa receptor blockade after coronary angioplasty [3] (multiple letters).” New England Journal of Medicine 337, no. 17 (1997): 1243–45. https://doi.org/10.1056/NEJM199710233371716.
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• Puopolo, A. L., M. J. Kennard, L. Mallatratt, M. A. Follen, N. A. Desbiens, A. F. C. Jr, R. Califf, et al. “Preferences for Cardiopulmonary Resuscitation.” Journal of Nursing Scholarship 29, no. 3 (1997): 229–35.
• Woodfield, S. L., C. F. Lundergan, J. S. Reiner, M. A. Thompson, S. C. Rohrbeck, Y. Deychak, J. O. Smith, et al. “Gender and acute myocardial infarction: is there a different response to thrombolysis?” Journal of the American College of Cardiology 29, no. 1 (January 1997): 35–42. https://doi.org/10.1016/s0735-1097(96)00449-4.
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• Jollis, J. G., E. R. DeLong, E. D. Peterson, L. H. Muhlbaier, D. F. Fortin, R. M. Califf, and D. B. Mark. “Outcome of acute myocardial infarction according to the specialty of the admitting physician.” N Engl J Med 335, no. 25 (December 19, 1996): 1880–87. https://doi.org/10.1056/NEJM199612193352505.
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• Shaw, L. J., E. D. Peterson, K. Kesler, V. Hasselblad, and R. M. Califf. “A metaanalysis of predischarge risk stratification after acute myocardial infarction with stress electrocardiographic, myocardial perfusion, and ventricular function imaging.” Am J Cardiol 78, no. 12 (December 15, 1996): 1327–37. https://doi.org/10.1016/s0002-9149(96)00653-4.
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• Aylward, P. E., R. G. Wilcox, J. H. Horgan, H. D. White, C. B. Granger, R. M. Califf, and E. J. Topol. “Relation of increased arterial blood pressure to mortality and stroke in the context of contemporary thrombolytic therapy for acute myocardial infarction. A randomized trial. GUSTO-I Investigators.” Ann Intern Med 125, no. 11 (December 1, 1996): 891–900. https://doi.org/10.7326/0003-4819-125-11-199612010-00004.
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• Califf, R. M., and L. K. Newby. “How much do we gain by reducing time to reperfusion therapy?” The American Journal of Cardiology 78, no. 12A (December 1996): 8–15. https://doi.org/10.1016/s0002-9149(96)00737-0.
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• Labinaz, M., M. H. Sketch, A. L. Stebbins, A. C. DeFranco, D. R. Holmes, N. S. Kleiman, A. Betriu, et al. “Thrombolytic therapy for patients with prior percutaneous transluminal coronary angioplasty and subsequent acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries.” The American Journal of Cardiology 78, no. 12 (December 1996): 1338–44. https://doi.org/10.1016/s0002-9149(96)00654-6.
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• Woodfield, S. L., C. F. Lundergan, J. S. Reiner, S. W. Greenhouse, M. A. Thompson, S. C. Rohrbeck, Y. Deychak, et al. “Angiographic findings and outcome in diabetic patients treated with thrombolytic therapy for acute myocardial infarction: the GUSTO-I experience.” Journal of the American College of Cardiology 28, no. 7 (December 1996): 1661–69. https://doi.org/10.1016/s0735-1097(96)00397-x.
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• Brener, S. J., F. S. Leya, C. Apperson-Hansen, M. J. Cowley, R. M. Califf, and E. J. Topol. “A comparison of debulking versus dilatation of bifurcation coronary arterial narrowings (from the CAVEAT I Trial). Coronary Angioplasty Versus Excisional Atherectomy Trial-I.” The American Journal of Cardiology 78, no. 9 (November 1996): 1039–41. https://doi.org/10.1016/s0002-9149(96)00531-0.
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• O’Brien, J. E., E. D. Peterson, G. P. Keeler, L. G. Berdan, E. M. Ohman, D. P. Faxon, A. K. Jacobs, E. J. Topol, and R. M. Califf. “Relation between estrogen replacement therapy and restenosis after percutaneous coronary interventions.” Journal of the American College of Cardiology 28, no. 5 (November 1996): 1111–18. https://doi.org/10.1016/s0735-1097(96)00306-3.
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• Ryan, T. J., J. L. Anderson, E. M. Antman, B. A. Braniff, N. H. Brooks, R. M. Califf, L. D. Hillis, et al. “ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).” Journal of the American College of Cardiology 28, no. 5 (November 1996): 1328–1428. https://doi.org/10.1016/s0735-1097(96)00392-0.
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• Ryan, T. J., J. L. Anderson, E. M. Antman, B. A. Braniff, N. H. Brooks, R. M. Califf, L. D. Hillis, et al. “ACC/AHA guidelines for the management of patients with acute myocardial infarction: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).” Circulation 94, no. 9 (November 1, 1996): 2341–50. https://doi.org/10.1161/01.cir.94.9.2341.
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• Schulman, S. P., P. J. Goldschmidt-Clermont, E. J. Topol, R. M. Califf, F. I. Navetta, J. T. Willerson, N. C. Chandra, et al. “Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina. A randomized multicenter trial.” Circulation 94, no. 9 (November 1, 1996): 2083–89. https://doi.org/10.1161/01.cir.94.9.2083.
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• Ohman, E. M., P. W. Armstrong, R. H. Christenson, C. B. Granger, H. A. Katus, C. W. Hamm, M. A. O’Hanesian, et al. “Cardiac troponin T levels for risk stratification in acute myocardial ischemia. GUSTO IIA Investigators.” N Engl J Med 335, no. 18 (October 31, 1996): 1333–41. https://doi.org/10.1056/NEJM199610313351801.
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• Pilote, L., D. P. Miller, R. M. Califf, J. S. Rao, W. D. Weaver, and E. J. Topol. “Determinants of the use of coronary angiography and revascularization after thrombolysis for acute myocardial infarction.” N Engl J Med 335, no. 16 (October 17, 1996): 1198–1205. https://doi.org/10.1056/NEJM199610173351606.
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• White, H. D., G. I. Barbash, R. M. Califf, R. J. Simes, C. B. Granger, W. D. Weaver, N. S. Kleiman, et al. “Age and outcome with contemporary thrombolytic therapy. Results from the GUSTO-I trial. Global Utilization of Streptokinase and TPA for Occluded coronary arteries trial.” Circulation 94, no. 8 (October 15, 1996): 1826–33. https://doi.org/10.1161/01.cir.94.8.1826.
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• Jelesoff, N. E., M. Feinglos, C. B. Granger, and R. M. Califf. “Outcomes of diabetic patients following acute myocardial infarction: a review of the major thrombolytic trials.” Coron Artery Dis 7, no. 10 (October 1996): 732–43. https://doi.org/10.1097/00019501-199610000-00006.
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• Lefkovits, J., J. C. Blankenship, K. M. Anderson, G. L. Stoner, J. D. Talley, S. J. Worley, H. F. Weisman, R. M. Califf, and E. J. Topol. “Increased risk of non-Q wave myocardial infarction after directional atherectomy is platelet dependent: evidence from the EPIC trial. Evaluation of c7E3 for the Prevention of Ischemic Complications.” Journal of the American College of Cardiology 28, no. 4 (October 1996): 849–55. https://doi.org/10.1016/s0735-1097(96)00239-2.
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• Naylor, C. D. “Left main stenosis.” Ann Thorac Surg 62, no. 4 (October 1996): 1239–41. https://doi.org/10.1016/0003-4975(96)85167-8.
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• Veldkamp, R. F., S. Sawchak, J. E. Pope, R. M. Califf, and M. W. Krucoff. “Performance of an automated real-time ST-segment analysis program to detect coronary occlusion and reperfusion.” Journal of Electrocardiology 29, no. 4 (October 1996): 257–63. https://doi.org/10.1016/s0022-0736(96)80090-2.
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• Connors, A. F., T. Speroff, N. V. Dawson, C. Thomas, F. E. Harrell, D. Wagner, N. Desbiens, et al. “The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators.” Jama 276, no. 11 (September 18, 1996): 889–97. https://doi.org/10.1001/jama.276.11.889.
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• Barefoot, J. C., M. J. Helms, D. B. Mark, J. A. Blumenthal, R. M. Califf, T. L. Haney, C. M. O’Connor, I. C. Siegler, and R. B. Williams. “Depression and long-term mortality risk in patients with coronary artery disease.” Am J Cardiol 78, no. 6 (September 15, 1996): 613–17. https://doi.org/10.1016/s0002-9149(96)00380-3.
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• Califf, R. M., H. D. White, F. Van de Werf, Z. Sadowski, P. W. Armstrong, A. Vahanian, M. L. Simoons, R. J. Simes, K. L. Lee, and E. J. Topol. “One-year results from the Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries (GUSTO-I) trial. GUSTO-I Investigators.” Circulation 94, no. 6 (September 15, 1996): 1233–38. https://doi.org/10.1161/01.cir.94.6.1233.
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• Califf, R. M. “The rationale for thrombolytic therapy.” Eur Heart J 17 Suppl E (September 1996): 2–8. https://doi.org/10.1093/eurheartj/17.suppl_e.2.
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• Eisenstein, E. L., D. B. Mark, and R. M. Califf. “Importance of cost and quality of life in decisions about routine angiography after acute myocardial infarction. The role of cost-effectiveness models.” Circulation 94, no. 5 (September 1, 1996): 869–71. https://doi.org/10.1161/01.cir.94.5.869.
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• Holmes, D. R., K. N. Garratt, J. M. Isner, M. Kearney, L. G. Berdan, R. S. Schwartz, R. M. Califf, and E. J. Topol. “Effect of subintimal resection on initial outcome and restenosis for native coronary lesions and saphenous vein graft disease treated by directional coronary atherectomy. A report from the CAVEAT I and II investigators. Coronary Angioplasty Versus Excisional Atherectomy Trial.” J Am Coll Cardiol 28, no. 3 (September 1996): 645–51. https://doi.org/10.1016/0735-1097(96)00185-4.
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• Hakim, R. B., J. M. Teno, F. E. Harrell, W. A. Knaus, N. Wenger, R. S. Phillips, P. Layde, R. Califf, A. F. Connors, and J. Lynn. “Factors associated with do-not-resuscitate orders: patients' preferences, prognoses, and physicians' judgments. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment.” Ann Intern Med 125, no. 4 (August 15, 1996): 284–93. https://doi.org/10.7326/0003-4819-125-4-199608150-00005.
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• Mark, D. B., J. D. Talley, E. J. Topol, L. Bowman, L. C. Lam, K. M. Anderson, J. G. Jollis, et al. “Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty. EPIC Investigators.” Circulation 94, no. 4 (August 15, 1996): 629–35. https://doi.org/10.1161/01.cir.94.4.629.
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• Lesnefsky, E. J., C. F. Lundergan, J. M. Hodgson, R. Nair, J. S. Reiner, S. W. Greenhouse, R. M. Califf, and A. M. Ross. “Increased left ventricular dysfunction in elderly patients despite successful thrombolysis: the GUSTO-I angiographic experience.” J Am Coll Cardiol 28, no. 2 (August 1996): 331–37. https://doi.org/10.1016/0735-1097(96)00148-9.
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• Midgette, A. S., J. L. Griffith, R. M. Califf, M. M. Laks, S. B. Dietz, J. R. Beshansky, and H. P. Selker. “Prediction of the infarct-related artery in acute myocardial infarction by a scoring system using summary ST-segment and T-wave changes.” The American Journal of Cardiology 78, no. 4 (August 1996): 389–95. https://doi.org/10.1016/s0002-9149(96)00325-6.
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• Peterson, E. D., W. R. Hathaway, K. M. Zabel, K. S. Pieper, C. B. Granger, G. S. Wagner, E. J. Topol, E. R. Bates, M. L. Simoons, and R. M. Califf. “Prognostic significance of precordial ST segment depression during inferior myocardial infarction in the thrombolytic era: results in 16,521 patients.” J Am Coll Cardiol 28, no. 2 (August 1996): 305–12. https://doi.org/10.1016/0735-1097(96)00133-7.
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• Rosenfeld, K. E., N. S. Wenger, R. S. Phillips, A. F. Connors, N. V. Dawson, P. Layde, R. M. Califf, H. Liu, J. Lynn, and R. K. Oye. “Factors associated with change in resuscitation preference of seriously ill patients. The SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.” Arch Intern Med 156, no. 14 (July 22, 1996): 1558–64.
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• Rosenfeld, K. E., N. S. Wenger, R. S. Phillips, A. F. Connors, N. V. Dawson, P. Layde, R. M. Califf, H. Liu, J. Lynn, and R. K. Oye. “Factors associated with change in resuscitation preference of seriously ill patients.” Archives of Internal Medicine 156, no. 14 (July 22, 1996): 1558–64. https://doi.org/10.1001/archinte.156.14.1558.
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• Anderson, J. L., L. A. Karagounis, and R. M. Califf. “Metaanalysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction.” Am J Cardiol 78, no. 1 (July 1, 1996): 1–8. https://doi.org/10.1016/s0002-9149(96)00217-2.
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• Phillips, R. S., M. B. Hamel, J. M. Teno, P. Bellamy, S. K. Broste, R. M. Califf, H. Vidaillet, R. B. Davis, L. H. Muhlbaier, and A. F. Connors. “Race, resource use, and survival in seriously ill hospitalized adults. The SUPPORT Investigators.” J Gen Intern Med 11, no. 7 (July 1996): 387–96. https://doi.org/10.1007/bf02600183.
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• Zahger, D., and P. K. Shah. “Effect of smoking status on response to thrombolytic therapy.” J Am Coll Cardiol 28, no. 1 (July 1996): 283. https://doi.org/10.1016/0735-1097(96)87143-9.
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• Califf, R. M., B. E. Tardiff, K. S. Pieper, and W. B. Hillegass. “Use of calcium channel antagonists in myocardial revascularization procedures.” The American Journal of Cardiology 77, no. 16 (June 1996): 26D-31D. https://doi.org/10.1016/s0002-9149(96)00305-0.
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• Newby, L. K., W. R. Rutsch, R. M. Califf, M. L. Simoons, P. E. Aylward, P. W. Armstrong, L. H. Woodlief, K. L. Lee, E. J. Topol, and F. Van de Werf. “Time from symptom onset to treatment and outcomes after thrombolytic therapy. GUSTO-1 Investigators.” J Am Coll Cardiol 27, no. 7 (June 1996): 1646–55. https://doi.org/10.1016/0735-1097(96)00053-8.
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• Granger, C. B., J. M. Miller, E. G. Bovill, A. Gruber, R. P. Tracy, M. W. Krucoff, C. Green, et al. “Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes.” Journal of Intravenous Nursing 19, no. 3 (May 1, 1996): 147–56.
• Jones, R. H., K. Kesler, H. R. Phillips, D. B. Mark, P. K. Smith, C. L. Nelson, M. F. Newman, J. G. Reves, R. W. Anderson, and R. M. Califf. “Long-term survival benefits of coronary artery bypass grafting and percutaneous transluminal angioplasty in patients with coronary artery disease.” The Journal of Thoracic and Cardiovascular Surgery 111, no. 5 (May 1996): 1013–25. https://doi.org/10.1016/s0022-5223(96)70378-1.
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• Kennard, M. J., T. Speroff, A. L. Puopolo, M. A. Follen, L. Mallatratt, R. Phillips, N. Desbiens, R. M. Califf, and A. F. Connors. “Participation of nurses in decision making for seriously ill adults.” Clin Nurs Res 5, no. 2 (May 1996): 199–219. https://doi.org/10.1177/105477389600500207.
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• Lefkovits, J., R. J. Ivanhoe, R. M. Califf, B. A. Bergelson, K. M. Anderson, G. L. Stoner, H. F. Weisman, and E. J. Topol. “Effects of platelet glycoprotein IIb/IIIa receptor blockade by a chimeric monoclonal antibody (abciximab) on acute and six-month outcomes after percutaneous transluminal coronary angioplasty for acute myocardial infarction. EPIC investigators.” The American Journal of Cardiology 77, no. 12 (May 1996): 1045–51. https://doi.org/10.1016/s0002-9149(96)00128-2.
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• Califf, R. M., P. W. Armstrong, J. R. Carver, R. B. D’Agostino, and W. E. Strauss. “27th Bethesda Conference: matching the intensity of risk factor management with the hazard for coronary disease events. Task Force 5. Stratification of patients into high, medium and low risk subgroups for purposes of risk factor management.” J Am Coll Cardiol 27, no. 5 (April 1996): 1007–19. https://doi.org/10.1016/0735-1097(96)87733-3.
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• Fetters, J. K., E. D. Peterson, L. J. Shaw, L. K. Newby, and R. M. Califf. “Sex-specific differences in coronary artery disease risk factors, evaluation, and treatment: have they been adequately evaluated?” American Heart Journal 131, no. 4 (April 1996): 796–813. https://doi.org/10.1016/s0002-8703(96)90289-6.
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• O’Connor, C. M., R. B. Meese, S. McNulty, K. D. Lucas, R. J. Carney, R. M. LeBoeuf, W. Maddox, et al. “A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. The DUCCS-II Investigators.” The American Journal of Cardiology 77, no. 10 (April 1996): 791–97. https://doi.org/10.1016/s0002-9149(97)89171-0.
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• Weaver, W. D., H. D. White, R. G. Wilcox, P. E. Aylward, D. Morris, A. Guerci, E. M. Ohman, et al. “Comparisons of characteristics and outcomes among women and men with acute myocardial infarction treated with thrombolytic therapy. GUSTO-I investigators.” Jama 275, no. 10 (March 13, 1996): 777–82.
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• Granger, C. B., J. Hirsch, R. M. Califf, J. Col, H. D. White, A. Betriu, L. H. Woodlief, et al. “Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: results from the GUSTO-I trial.” Circulation 93, no. 5 (March 1, 1996): 870–78. https://doi.org/10.1161/01.cir.93.5.870.
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• Mahaffey, K. W., C. B. Granger, R. Collins, C. M. O’Connor, E. M. Ohman, S. D. Bleich, J. J. Col, and R. M. Califf. “Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy.” The American Journal of Cardiology 77, no. 8 (March 1996): 551–56. https://doi.org/10.1016/s0002-9149(97)89305-8.
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• Newby, L. K., R. M. Califf, A. Guerci, W. D. Weaver, J. Col, J. H. Horgan, D. B. Mark, et al. “Early discharge in the thrombolytic era: an analysis of criteria for uncomplicated infarction from the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) trial.” J Am Coll Cardiol 27, no. 3 (March 1, 1996): 625–32. https://doi.org/10.1016/0735-1097(95)00513-7.
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• Sgarbossa, E. B., S. L. Pinski, A. Barbagelata, D. A. Underwood, K. B. Gates, E. J. Topol, R. M. Califf, and G. S. Wagner. “Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators.” N Engl J Med 334, no. 8 (February 22, 1996): 481–87. https://doi.org/10.1056/NEJM199602223340801.
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• Narins, C. R., W. B. Hillegass, C. L. Nelson, J. E. Tcheng, R. A. Harrington, H. R. Phillips, R. S. Stack, and R. M. Califf. “Relation between activated clotting time during angioplasty and abrupt closure.” Circulation 93, no. 4 (February 15, 1996): 667–71. https://doi.org/10.1161/01.cir.93.4.667.
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• Califf, R. M., J. G. Jollis, and E. D. Peterson. “Operator-specific outcomes. A call to professional responsibility.” Circulation 93, no. 3 (February 1, 1996): 403–6. https://doi.org/10.1161/01.cir.93.3.403.
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• Jollis, J. G., and R. M. Califf. “A randomized study would answer the question.” Ann Thorac Surg 61, no. 2 (February 1996): 513–14. https://doi.org/10.1016/0003-4975(95)01107-2.
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• Phillips, R. S., N. S. Wenger, J. Teno, R. K. Oye, S. Youngner, R. Califf, P. Layde, N. Desbiens, A. F. Connors, and J. Lynn. “Choices of seriously ill patients about cardiopulmonary resuscitation: correlates and outcomes. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.” The American Journal of Medicine 100, no. 2 (February 1996): 128–37. https://doi.org/10.1016/s0002-9343(97)89450-8.
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• Aguirre, F. V., E. J. Topol, K. M. Anderson, N. S. Kleiman, H. F. Weisman, S. E. FitzPatrick, and R. M. Califf. “Clinical Benefit within Patient Subgroups Receiving c7E3 Fab (Abciximab) During Percutaneous Coronary Revascularization: Subgroup Analysis from the EPIC Trial.” J Invasive Cardiol 8 Suppl B (1996): 21B-29B.
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• Barsness, G. W., E. M. Ohman, R. M. Califf, D. J. Kereiakes, B. S. George, and E. J. Topol. “The thrombolysis and angioplasty in myocardial infarction (TAMI) trials: A decade of reperfusion strategies.” Journal of Interventional Cardiology 9, no. 2 (January 1, 1996): 89–115. https://doi.org/10.1111/j.1540-8183.1996.tb00604.x.
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• Holmes, D. R., K. N. Garratt, J. M. Isner, M. Kearney, L. G. Berdan, R. S. Schwartz, R. M. Califf, and E. J. Topol. “Effect of subintimal resection on initial outcome and restenosis for native coronary lesions and saphenous vein graft disease treated by directional coronary atherectomy. A report from the CAVEAT I and II investigators.” Journal of the American College of Cardiology 28, no. 3 (January 1, 1996): 645–51. https://doi.org/10.1016/S0735-1097(96)00185-4.
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• Newby, L. K., and R. M. Califf. “Identifying Patient Risk: The Basis for Rational Discharge Planning After Acute Myocardial Infarction.” J Thromb Thrombolysis 3, no. 2 (1996): 107–15. https://doi.org/10.1007/bf00132403.
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• Prendergast, T. J., P. J. Dougherty, W. J. Donnelly, R. R. Frank, M. L. Campbell, J. E. Parrillo, G. A. Sachs, et al. “The SUPPORT project and improving care for seriously ill patients [1].” Journal of the American Medical Association 275, no. 16 (1996): 1227–32. https://doi.org/10.1001/jama.275.16.1227.
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• Puma, J. A., R. M. Califf, and M. H. Sketch. “The natural history of single vessel chronic total occlusions.” Acc Current Journal Review 5, no. 2 (January 1, 1996): 73–76. https://doi.org/10.1016/1062-1458(96)82291-4.
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• Califf, R. M. “Implications for cost-effectiveness.” The American Journal of Cardiology 76, no. 16 (December 1, 1995): 1182. https://doi.org/10.1016/S0002-9149(99)80332-4.
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• Fortin, D. F., R. M. Califf, D. B. Pryor, and D. B. Mark. “The way of the future redux.” The American Journal of Cardiology 76, no. 16 (December 1995): 1177–82. https://doi.org/10.1016/s0002-9149(99)80331-2.
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• Harrington, R. A., N. S. Kleiman, K. Kottke-Marchant, A. M. Lincoff, J. E. Tcheng, K. N. Sigmon, D. Joseph, G. Rios, K. Trainor, and D. Rose. “Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention.” The American Journal of Cardiology 76, no. 17 (December 1995): 1222–27. https://doi.org/10.1016/s0002-9149(99)80345-2.
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• Karnash, S. L., C. B. Granger, H. D. White, L. H. Woodlief, E. J. Topol, and R. M. Califf. “Treating menstruating women with thrombolytic therapy: insights from the global utilization of streptokinase and tissue plasminogen activator for occluded coronary arteries (GUSTO-I) trial.” J Am Coll Cardiol 26, no. 7 (December 1995): 1651–56. https://doi.org/10.1016/0735-1097(95)00386-x.
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• Gore, J. M., C. B. Granger, M. L. Simoons, M. A. Sloan, W. D. Weaver, H. D. White, G. I. Barbash, F. Van de Werf, P. E. Aylward, and E. J. Topol. “Stroke after thrombolysis. Mortality and functional outcomes in the GUSTO-I trial. Global Use of Strategies to Open Occluded Coronary Arteries.” Circulation 92, no. 10 (November 15, 1995): 2811–18. https://doi.org/10.1161/01.cir.92.10.2811.
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• Holmes, D. R., J. B. Simpson, L. G. Berdan, R. S. Gottlieb, F. Leya, G. P. Keeler, R. M. Califf, and E. J. Topol. “Abrupt closure: the CAVEAT I experience. Coronary Angioplasty Versus Excisional Atherectomy Trial.” J Am Coll Cardiol 26, no. 6 (November 15, 1995): 1494–1500. https://doi.org/10.1016/0735-1097(95)00339-8.
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• Barbagelata, A., C. B. Granger, E. J. Topol, S. J. Worley, D. J. Kereiakes, B. S. George, E. M. Ohman, J. D. Leimberger, D. B. Mark, and R. M. Califf. “Frequency, significance, and cost of recurrent ischemia after thrombolytic therapy for acute myocardial infarction. TAMI Study Group.” The American Journal of Cardiology 76, no. 14 (November 1995): 1007–13. https://doi.org/10.1016/s0002-9149(99)80285-9.
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• Barbash, G. I., J. Reiner, H. D. White, R. G. Wilcox, P. W. Armstrong, Z. Sadowski, D. Morris, P. Aylward, L. H. Woodlief, and E. J. Topol. “Evaluation of paradoxic beneficial effects of smoking in patients receiving thrombolytic therapy for acute myocardial infarction: mechanism of the "smoker's paradox" from the GUSTO-I trial, with angiographic insights. Global Utilization of Streptokinase and Tissue-Plasminogen Activator for Occluded Coronary Arteries.” J Am Coll Cardiol 26, no. 5 (November 1, 1995): 1222–29. https://doi.org/10.1016/0735-1097(95)00299-5.
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• Califf, R. M., A. M. Lincoff, J. E. Tcheng, and E. J. Topol. “An overview of the results of the EPIC trial.” Eur Heart J 16 Suppl L (November 1995): 43–49. https://doi.org/10.1093/eurheartj/16.suppl_l.43.
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• Levine, M. N., S. Z. Goldhaber, J. M. Gore, J. Hirsh, and R. M. Califf. “Hemorrhagic complications of thrombolytic therapy in the treatment of myocardial infarction and venous thromboembolism.” Chest 108, no. 4 Suppl (October 1995): 291S-301S. https://doi.org/10.1378/chest.108.4_supplement.291s.
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• Omoigui, N. A., R. M. Califf, K. Pieper, G. Keeler, M. A. O’Hanesian, L. G. Berdan, D. B. Mark, J. D. Talley, and E. J. Topol. “Peripheral vascular complications in the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT-I).” J Am Coll Cardiol 26, no. 4 (October 1995): 922–30. https://doi.org/10.1016/0735-1097(95)00263-4.
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• Weitz, J. I., R. M. Califf, J. S. Ginsberg, J. Hirsh, and P. Théroux. “New antithrombotics.” Chest 108, no. 4 Suppl (October 1995): 471S-485S. https://doi.org/10.1378/chest.108.4_supplement.471s.
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• Califf, R. M. “Acute ischemic syndromes.” Med Clin North Am 79, no. 5 (September 1995): 999–1024. https://doi.org/10.1016/s0025-7125(16)30018-9.
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• Califf, R. M. “Restenosis: the cost to society.” Am Heart J 130, no. 3 Pt 2 (September 1995): 680–84. https://doi.org/10.1016/0002-8703(95)90306-2.
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• Holmes, D. R., E. R. Bates, N. S. Kleiman, Z. Sadowski, J. H. Horgan, D. C. Morris, R. M. Califf, P. B. Berger, and E. J. Topol. “Contemporary reperfusion therapy for cardiogenic shock: the GUSTO-I trial experience. The GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” J Am Coll Cardiol 26, no. 3 (September 1995): 668–74. https://doi.org/10.1016/0735-1097(95)00215-p.
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• Mark, D. B., W. W. O’Neill, B. Brodie, R. Ivanhoe, W. Knopf, G. Taylor, J. H. O’Keefe, C. L. Grines, L. Davidson-Ray, and J. D. Knight. “Baseline and 6-month costs of primary angioplasty therapy for acute myocardial infarction: results from the primary angioplasty registry.” J Am Coll Cardiol 26, no. 3 (September 1995): 688–95. https://doi.org/10.1016/0735-1097(95)00246-z.
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• Pilote, L., R. M. Califf, S. Sapp, D. P. Miller, D. B. Mark, W. D. Weaver, J. M. Gore, P. W. Armstrong, E. M. Ohman, and E. J. Topol. “Regional variation across the United States in the management of acute myocardial infarction. GUSTO-1 Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” N Engl J Med 333, no. 9 (August 31, 1995): 565–72. https://doi.org/10.1056/NEJM199508313330907.
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• Lefkovits, J., D. R. Holmes, R. M. Califf, R. D. Safian, K. Pieper, G. Keeler, and E. J. Topol. “Predictors and sequelae of distal embolization during saphenous vein graft intervention from the CAVEAT-II trial. Coronary Angioplasty Versus Excisional Atherectomy Trial.” Circulation 92, no. 4 (August 15, 1995): 734–40. https://doi.org/10.1161/01.cir.92.4.734.
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• Califf, R. M. “How should clinicians interpret clinical trials?” Cardiol Clin 13, no. 3 (August 1995): 459–68.
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• Hlatky, M. A., L. C. Lam, K. L. Lee, N. E. Clapp-Channing, R. B. Williams, D. B. Pryor, R. M. Califf, and D. B. Mark. “Job strain and the prevalence and outcome of coronary artery disease.” Circulation 92, no. 3 (August 1, 1995): 327–33. https://doi.org/10.1161/01.cir.92.3.327.
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• Van de Werf, F., R. M. Califf, P. W. Armstrong, E. R. Bates, A. M. Ross, N. S. Kleinman, and E. J. Topol. “Progress culminating from ten years of clinical trials on thrombolysis for acute myocardial infarction. GUSTO-I Steering Committee. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” Eur Heart J 16, no. 8 (August 1995): 1024–26. https://doi.org/10.1093/oxfordjournals.eurheartj.a061042.
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• Werf, F. V. D., R. M. Califf, P. W. Armstrong, E. R. Bates, A. M. Ross, and N. S. Kleinman. “Progress culminating from ten years of clinical trials on thrombolysis for acute myocardial infarction.” European Heart Journal 16, no. 8 (August 1, 1995): 1024–26.
• Puma, J. A., M. H. Sketch, J. E. Tcheng, R. A. Harrington, H. R. Phillips, R. S. Stack, and R. M. Califf. “Percutaneous revascularization of chronic coronary occlusions: an overview.” J Am Coll Cardiol 26, no. 1 (July 1995): 1–11. https://doi.org/10.1016/0735-1097(95)00156-t.
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• Hamel, M. B., L. Goldman, J. Teno, J. Lynn, R. B. Davis, F. E. Harrell, A. F. Connors, R. Califf, P. Kussin, and P. Bellamy. “Identification of comatose patients at high risk for death or severe disability. SUPPORT Investigators. Understand Prognoses and Preferences for Outcomes and Risks of Treatments.” Jama 273, no. 23 (June 21, 1995): 1842–48.
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• Aguirre, F. V., E. J. Topol, J. J. Ferguson, K. Anderson, J. C. Blankenship, R. R. Heuser, K. Sigmon, M. Taylor, R. Gottlieb, and G. Hanovich. “Bleeding complications with the chimeric antibody to platelet glycoprotein IIb/IIIa integrin in patients undergoing percutaneous coronary intervention. EPIC Investigators.” Circulation 91, no. 12 (June 15, 1995): 2882–90. https://doi.org/10.1161/01.cir.91.12.2882.
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• Harrington, R. A., A. M. Lincoff, R. M. Califf, D. R. Holmes, L. G. Berdan, M. A. O’Hanesian, G. P. Keeler, K. N. Garratt, E. M. Ohman, and D. B. Mark. “Characteristics and consequences of myocardial infarction after percutaneous coronary intervention: insights from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT).” J Am Coll Cardiol 25, no. 7 (June 1995): 1693–99. https://doi.org/10.1016/0735-1097(95)00091-h.
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• Holmes, D. R., R. M. Califf, and E. J. Topol. “Lessons we have learned from the GUSTO trial. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries.” J Am Coll Cardiol 25, no. 7 Suppl (June 1995): 10S-17S. https://doi.org/10.1016/0735-1097(95)00188-a.
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• Langer, A., M. W. Krucoff, P. Klootwijk, R. Veldkamp, M. L. Simoons, C. Granger, R. M. Califf, and P. W. Armstrong. “Noninvasive assessment of speed and stability of infarct-related artery reperfusion: results of the GUSTO ST segment monitoring study. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” J Am Coll Cardiol 25, no. 7 (June 1995): 1552–57. https://doi.org/10.1016/0735-1097(95)00110-p.
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• Mark, D. B., M. A. Hlatky, R. M. Califf, C. D. Naylor, K. L. Lee, P. W. Armstrong, G. Barbash, H. White, M. L. Simoons, and C. L. Nelson. “Cost effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarction.” N Engl J Med 332, no. 21 (May 25, 1995): 1418–24. https://doi.org/10.1056/NEJM199505253322106.
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• Van de Werf, F., E. J. Topol, K. L. Lee, L. H. Woodlief, C. B. Granger, P. W. Armstrong, G. I. Barbash, J. R. Hampton, A. Guerci, and R. J. Simes. “Variations in patient management and outcomes for acute myocardial infarction in the United States and other countries. Results from the GUSTO trial. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” Jama 273, no. 20 (May 24, 1995): 1586–91. https://doi.org/10.1001/jama.273.20.1586.
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• Boehrer, J. D., S. G. Ellis, K. Pieper, D. R. Holmes, G. P. Keeler, D. Debowey, A. T. Chapekis, F. Leya, M. R. Mooney, and R. S. Gottlieb. “Directional atherectomy versus balloon angioplasty for coronary ostial and nonostial left anterior descending coronary artery lesions: results from a randomized multicenter trial. The CAVEAT-I investigators. Coronary Angioplasty Versus Excisional Atherectomy Trial.” J Am Coll Cardiol 25, no. 6 (May 1995): 1380–86. https://doi.org/10.1016/0735-1097(95)00008-r.
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• Burnett, R. E., J. A. Blumenthal, D. B. Mark, J. D. Leimberger, and R. M. Califf. “Distinguishing between early and late responders to symptoms of acute myocardial infarction.” The American Journal of Cardiology 75, no. 15 (May 1995): 1019–22. https://doi.org/10.1016/s0002-9149(99)80716-4.
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• Lincoff, A. M., E. J. Topol, R. M. Califf, K. N. Sigmon, K. L. Lee, E. M. Ohman, U. Rosenschein, and S. G. Ellis. “Significance of a coronary artery with thrombolysis in myocardial infarction grade 2 flow "patency" (outcome in the thrombolysis and angioplasty in myocardial infarction trials). Thrombolysis and Angioplasty in Myocardial Infarction Study Group.” The American Journal of Cardiology 75, no. 14 (May 1995): 871–76. https://doi.org/10.1016/s0002-9149(99)80678-x.
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• Elliott, J. M., L. G. Berdan, D. R. Holmes, J. M. Isner, S. B. King, G. P. Keeler, M. Kearney, R. M. Califf, and E. J. Topol. “One-year follow-up in the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT I).” Circulation 91, no. 8 (April 15, 1995): 2158–66. https://doi.org/10.1161/01.cir.91.8.2158.
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• Tcheng, J. E., R. A. Harrington, K. Kottke-Marchant, N. S. Kleiman, S. G. Ellis, D. J. Kereiakes, M. J. Mick, F. I. Navetta, J. E. Smith, and S. J. Worley. “Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT Investigators.” Circulation 91, no. 8 (April 15, 1995): 2151–57. https://doi.org/10.1161/01.cir.91.8.2151.
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• Granger, C. B., J. M. Miller, E. G. Bovill, A. Gruber, R. P. Tracy, M. W. Krucoff, C. Green, E. Berrios, R. A. Harrington, and E. M. Ohman. “Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes.” Circulation 91, no. 7 (April 1, 1995): 1929–35. https://doi.org/10.1161/01.cir.91.7.1929.
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• Holmes, D. R., E. J. Topol, R. M. Califf, L. G. Berdan, F. Leya, P. B. Berger, P. L. Whitlow, R. D. Safian, A. G. Adelman, and M. A. Kellett. “A multicenter, randomized trial of coronary angioplasty versus directional atherectomy for patients with saphenous vein bypass graft lesions. CAVEAT-II Investigators.” Circulation 91, no. 7 (April 1, 1995): 1966–74. https://doi.org/10.1161/01.cir.91.7.1966.
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• Simes, R. J., E. J. Topol, D. R. Holmes, H. D. White, W. R. Rutsch, A. Vahanian, M. L. Simoons, D. Morris, A. Betriu, and R. M. Califf. “Link between the angiographic substudy and mortality outcomes in a large randomized trial of myocardial reperfusion. Importance of early and complete infarct artery reperfusion. GUSTO-I Investigators.” Circulation 91, no. 7 (April 1, 1995): 1923–28. https://doi.org/10.1161/01.cir.91.7.1923.
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• Lee, K. L., L. H. Woodlief, E. J. Topol, W. D. Weaver, A. Betriu, J. Col, M. Simoons, P. Aylward, F. Van de Werf, and R. M. Califf. “Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators.” Circulation 91, no. 6 (March 15, 1995): 1659–68. https://doi.org/10.1161/01.cir.91.6.1659.
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• Moliterno, D. J., R. M. Califf, F. V. Aguirre, K. Anderson, K. N. Sigmon, H. F. Weisman, and E. J. Topol. “Effect of platelet glycoprotein IIb/IIIa integrin blockade on activated clotting time during percutaneous transluminal coronary angioplasty or directional atherectomy (the EPIC trial). Evaluation of c7E3 Fab in the Prevention of Ischemic Complications trial.” The American Journal of Cardiology 75, no. 8 (March 1995): 559–62. https://doi.org/10.1016/s0002-9149(99)80616-x.
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• Harrington, R. A., and R. M. Califf. “Emerging role of PTCA in acute MI.” Journal of Myocardial Ischemia 7, no. 1 (February 17, 1995): 23–28.
• Knaus, W. A., F. E. Harrell, J. Lynn, L. Goldman, R. S. Phillips, A. F. Connors, N. V. Dawson, et al. “The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments.” Ann Intern Med 122, no. 3 (February 1, 1995): 191–203. https://doi.org/10.7326/0003-4819-122-3-199502010-00007.
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• Grines, C. L., E. J. Topol, W. W. O’Neill, B. S. George, D. Kereiakes, H. R. Phillips, J. D. Leimberger, L. H. Woodlief, and R. M. Califf. “Effect of cigarette smoking on outcome after thrombolytic therapy for myocardial infarction.” Circulation 91, no. 2 (January 15, 1995): 298–303. https://doi.org/10.1161/01.cir.91.2.298.
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• Christenson, R. H., E. M. Ohman, E. J. Topol, M. A. O’Hanesian, K. N. Sigmon, S. H. Duh -, D. Kereiakes, et al. “Creatine kinase MM and MB isoforms in patients receiving thrombolytic therapy and acute angiography.” Clinical Chemistry 41, no. 6 (January 1, 1995): 844–52.
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• Maynard, C., H. P. Selker, J. R. Beshansky, J. L. Griffith, C. H. Schmid, R. M. Califf, R. B. D’Agostino, M. M. Laks, K. L. Lee, and G. S. Wagner. “The exclusion of women from clinical trials of thrombolytic therapy: implications for developing the thrombolytic predictive instrument database.” Med Decis Making 15, no. 1 (January 1995): 38–43. https://doi.org/10.1177/0272989X9501500107.
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• Moliterno, D. J., R. A. Harrington, R. M. Califf, H. J. Rapold, and E. J. Topol. “Randomized, Placebo-Controlled Study of Lamifiban with Thrombolytic Therapy for the Treatment of Acute Myocardial Infarction: Rationale and Design for the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) Study.” J Thromb Thrombolysis 2, no. 3 (1995): 165–69. https://doi.org/10.1007/bf01062706.
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• Peterson, E. D., and R. M. Califf. “The complexity of studying coronary heart disease in women.” Ann Epidemiol 5, no. 1 (January 1995): 79–81. https://doi.org/10.1016/1047-2797(94)00045-u.
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• Steg, P. G., M. Ziol, O. Tahlil, C. Robert, P. Masson, D. Pruneau, P. Bruneval, and P. Bélichard. “Reduction of intimai hyperplasia by naroparcil, a 4-methylumbelliferyl β-D-xyloside analogue, after arterial injury in the hypercholesterolemic rabbit.” Circulation Research 77, no. 5 (1995): 919–26.
• Topol, E. J., R. N. Califf, K. M. Sigmon, and K. L. Lee. “Cardiovascular health and disease in women: Thrombolytic therapy for women with acute myocardial infarction: Is there a gender gap?” Cardiovascular Reviews and Reports 16, no. 1 (January 1, 1995): 22–27.
• Granger, C. B., H. D. White, E. R. Bates, E. M. Ohman, and R. M. Califf. “A pooled analysis of coronary arterial patency and left ventricular function after intravenous thrombolysis for acute myocardial infarction.” Am J Cardiol 74, no. 12 (December 15, 1994): 1220–28. https://doi.org/10.1016/0002-9149(94)90552-5.
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• Boehrer, J. D., D. J. Kereiakes, F. I. Navetta, R. M. Califf, and E. J. Topol. “Effects of profound platelet inhibition with c7E3 before coronary angioplasty on complications of coronary bypass surgery. EPIC Investigators. Evaluation Prevention of Ischemic Complications.” Am J Cardiol 74, no. 11 (December 1, 1994): 1166–70. https://doi.org/10.1016/0002-9149(94)90474-x.
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• Kleiman, N. S., H. D. White, E. M. Ohman, A. M. Ross, L. H. Woodlief, R. M. Califf, D. R. Holmes, E. Bates, M. Pfisterer, and A. Vahanian. “Mortality within 24 hours of thrombolysis for myocardial infarction. The importance of early reperfusion. The GUSTO Investigators, Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” Circulation 90, no. 6 (December 1994): 2658–65. https://doi.org/10.1161/01.cir.90.6.2658.
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• Kleiman, N. S., H. D. White, E. M. Ohman, A. M. Ross, L. H. Woodlief, R. M. Califf, D. R. Holmes, et al. “Mortality within 24 hours of thrombolysis for myocardial infarction: The importance of early reperfusion.” Circulation 90, no. 6 (December 1, 1994): 2658–65.
• Zabel, K. M., and R. M. Califf. “The value of exercise thallium imaging.” Ann Intern Med 121, no. 11 (December 1, 1994): 891–93. https://doi.org/10.7326/0003-4819-121-11-199412010-00013.
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• Reiner, J. S., C. F. Lundergan, M. van den Brand, J. Boland, M. A. Thompson, J. Machecourt, A. Py, G. S. Pilcher, C. A. Fink, and J. R. Burton. “Early angiography cannot predict postthrombolytic coronary reocclusion: observations from the GUSTO angiographic study. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries.” J Am Coll Cardiol 24, no. 6 (November 15, 1994): 1439–44. https://doi.org/10.1016/0735-1097(94)90137-6.
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• Mark, D. B., C. D. Naylor, M. A. Hlatky, R. M. Califf, E. J. Topol, C. B. Granger, J. D. Knight, C. L. Nelson, K. L. Lee, and N. E. Clapp-Channing. “Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States.” N Engl J Med 331, no. 17 (October 27, 1994): 1130–35. https://doi.org/10.1056/NEJM199410273311706.
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• Selker, H. P., J. R. Beshansky, C. H. Schmid, J. L. Griffith, W. T. Longstreth, C. M. O’Connor, L. R. Caplan, E. W. Massey, R. B. D’Agostino, and M. M. Laks. “Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results.” Circulation 90, no. 4 (October 1994): 1657–61. https://doi.org/10.1161/01.cir.90.4.1657.
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• Tcheng, J. E., S. G. Ellis, B. S. George, D. J. Kereiakes, N. S. Kleiman, J. D. Talley, A. L. Wang, H. F. Weisman, R. M. Califf, and E. J. Topol. “Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty.” Circulation 90, no. 4 (October 1994): 1757–64. https://doi.org/10.1161/01.cir.90.4.1757.
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• Tenaglia, A. N., D. F. Fortin, R. M. Califf, D. J. Frid, C. L. Nelson, L. Gardner, M. Miller, F. I. Navetta, J. E. Smith, and J. E. Tcheng. “Predicting the risk of abrupt vessel closure after angioplasty in an individual patient.” J Am Coll Cardiol 24, no. 4 (October 1994): 1004–11. https://doi.org/10.1016/0735-1097(94)90862-1.
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• Ellis, S. G., A. M. Lincoff, B. S. George, D. J. Kereiakes, E. M. Ohman, M. W. Krucoff, R. M. Califf, and E. J. Topol. “Randomized evaluation of coronary angioplasty for early TIMI 2 flow after thrombolytic therapy for the treatment of acute myocardial infarction: A new look at an old study.” Coronary Artery Disease 5, no. 7 (September 13, 1994): 611–15.
• Califf, R. M., and C. B. Granger. “Trials of new antithrombin agents.” Journal of Myocardial Ischemia 6, no. 6 (August 8, 1994): 10–14.
• Holmes, D. R., E. J. Topol, A. G. Adelman, E. A. Cohen, and R. M. Califf. “Randomized trials of directional coronary atherectomy: implications for clinical practice and future investigation.” J Am Coll Cardiol 24, no. 2 (August 1994): 431–39. https://doi.org/10.1016/0735-1097(94)90300-x.
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• Ohman, E. M., B. S. George, C. J. White, M. J. Kern, P. A. Gurbel, R. J. Freedman, C. Lundergan, J. R. Hartmann, J. D. Talley, and M. J. Frey. “Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group.” Circulation 90, no. 2 (August 1994): 792–99. https://doi.org/10.1161/01.cir.90.2.792.
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• Topol, E. J., R. M. Califf, and K. L. Lee. “More on the GUSTO trial.” N Engl J Med 331, no. 4 (July 28, 1994): 277–78. https://doi.org/10.1056/NEJM199407283310418.
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• Brodie, B. R., C. L. Grines, R. Ivanhoe, W. Knopf, G. Taylor, J. O’Keefe, R. A. Weintraub, L. G. Berdan, J. E. Tcheng, and L. H. Woodlief. “Six-month clinical and angiographic follow-up after direct angioplasty for acute myocardial infarction. Final results from the Primary Angioplasty Registry.” Circulation 90, no. 1 (July 1994): 156–62. https://doi.org/10.1161/01.cir.90.1.156.
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• Ellis, S. G., A. M. Lincoff, B. S. George, D. J. Kereiakes, E. M. Ohman, M. W. Krucoff, R. M. Califf, and E. J. Topol. “Randomized evaluation of coronary angioplasty for early TIMI 2 flow after thrombolytic therapy for the treatment of acute myocardial infarction: a new look at an old study. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.” Coron Artery Dis 5, no. 7 (July 1994): 611–15. https://doi.org/10.1097/00019501-199407000-00009.
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• Wall, T. C., R. M. Califf, J. Blankenship, J. D. Talley, M. Tannenbaum, M. Schwaiger, G. Gacioch, M. D. Cohen, M. Sanz, and J. D. Leimberger. “Intravenous Fluosol in the treatment of acute myocardial infarction. Results of the Thrombolysis and Angioplasty in Myocardial Infarction 9 Trial. TAMI 9 Research Group.” Circulation 90, no. 1 (July 1994): 114–20. https://doi.org/10.1161/01.cir.90.1.114.
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• Califf, R. M., and J. R. Bengtson. “Cardiogenic shock.” N Engl J Med 330, no. 24 (June 16, 1994): 1724–30. https://doi.org/10.1056/NEJM199406163302406.
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• Lee, K. L., R. M. Califf, and E. J. Topol. “The last word on GUSTO, for now.” Ann Intern Med 120, no. 11 (June 1, 1994): 970. https://doi.org/10.7326/0003-4819-120-11-199406010-00014.
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• Veldkamp, R. F., C. L. Green, M. L. Wilkins, J. E. Pope, S. T. Sawchak, J. A. Ryan, R. M. Califf, G. S. Wagner, and M. W. Krucoff. “Comparison of continuous ST-segment recovery analysis with methods using static electrocardiograms for noninvasive patency assessment during acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 7 Study Group.” Am J Cardiol 73, no. 15 (June 1, 1994): 1069–74. https://doi.org/10.1016/0002-9149(94)90285-2.
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• Lee, K. L., R. M. Califf, J. Simes, F. Van de Werf, E. J. Topol, P. M. Ridker, C. J. O’Donnell, V. J. Marder, and C. H. Hennekens. “Holding GUSTO up to the light.” Annals of Internal Medicine 120, no. 10 (May 19, 1994): 876–85.
• Lee, K. L., R. M. Califf, J. Simes, F. Van de Werf, and E. J. Topol. “Holding GUSTO up to the light. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.” Ann Intern Med 120, no. 10 (May 15, 1994): 876–81. https://doi.org/10.7326/0003-4819-120-10-199405150-00009.
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• Harrington, R. A., and R. M. Califf. “The role of angioplasty after failed thrombolysis for acute myocardial infarction.” Coron Artery Dis 5, no. 5 (May 1994): 392–98. https://doi.org/10.1097/00019501-199405000-00005.
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• Hillegass, W. B., E. M. Ohman, J. D. Leimberger, and R. M. Califf. “A meta-analysis of randomized trials of calcium antagonists to reduce restenosis after coronary angioplasty.” Am J Cardiol 73, no. 12 (May 1, 1994): 835–39. https://doi.org/10.1016/0002-9149(94)90805-2.
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• Mark, D. B., C. L. Nelson, R. M. Califf, F. E. Harrell, K. L. Lee, R. H. Jones, D. F. Fortin, R. S. Stack, D. D. Glower, and L. R. Smith. “Continuing evolution of therapy for coronary artery disease. Initial results from the era of coronary angioplasty.” Circulation 89, no. 5 (May 1994): 2015–25. https://doi.org/10.1161/01.cir.89.5.2015.
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• Mark, D. B., L. K. Shaw, E. R. DeLong, R. M. Califf, and D. B. Pryor. “Absence of sex bias in the referral of patients for cardiac catheterization.” N Engl J Med 330, no. 16 (April 21, 1994): 1101–6. https://doi.org/10.1056/NEJM199404213301601.
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• EPIC Investigators, Adrian. “Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty.” N Engl J Med 330, no. 14 (April 7, 1994): 956–61. https://doi.org/10.1056/NEJM199404073301402.
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• Califf, R. M., and D. B. Mark. “Percutaneous intervention, surgery, and medical therapy: a perspective from the Duke Databank for Cardiovascular Diseases.” Semin Thorac Cardiovasc Surg 6, no. 2 (April 1994): 120–28.
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• Milner, L. S. “Double-blind coumadin research--an ethical dilemma.” Am J Cardiol 73, no. 9 (April 1, 1994): 725–26. https://doi.org/10.1016/0002-9149(94)90953-9.
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• O’Neill, W. W., B. R. Brodie, R. Ivanhoe, W. Knopf, G. Taylor, J. O’Keefe, C. L. Grines, R. Weintraub, B. G. Sickinger, and L. G. Berdan. “Primary coronary angioplasty for acute myocardial infarction (the Primary Angioplasty Registry).” Am J Cardiol 73, no. 9 (April 1, 1994): 627–34. https://doi.org/10.1016/0002-9149(94)90924-5.
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• Topol, E. J., R. M. Califf, H. F. Weisman, S. G. Ellis, J. E. Tcheng, S. Worley, R. Ivanhoe, B. S. George, D. Fintel, and M. Weston. “Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: results at six months. The EPIC Investigators.” Lancet (London, England) 343, no. 8902 (April 1994): 881–86. https://doi.org/10.1016/s0140-6736(94)90007-8.
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• Topol, E. J., V. Fuster, R. A. Harrington, R. M. Califf, N. S. Kleiman, D. J. Kereiakes, M. Cohen, A. Chapekis, H. K. Gold, and M. A. Tannenbaum. “Recombinant hirudin for unstable angina pectoris. A multicenter, randomized angiographic trial.” Circulation 89, no. 4 (April 1994): 1557–66. https://doi.org/10.1161/01.cir.89.4.1557.
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• Harrington, R. A., D. C. Sane, R. M. Califf, K. N. Sigmon, C. W. Abbottsmith, R. J. Candela, K. L. Lee, and E. J. Topol. “Clinical importance of thrombocytopenia occurring in the hospital phase after administration of thrombolytic therapy for acute myocardial infarction. The Thrombolysis and Angioplasty in Myocardial Infarction Study Group.” J Am Coll Cardiol 23, no. 4 (March 15, 1994): 891–98. https://doi.org/10.1016/0735-1097(94)90634-3.
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• Hillegass, W. B., J. G. Jollis, C. B. Granger, E. M. Ohman, R. M. Califf, and D. B. Mark. “Intracranial hemorrhage risk and new thrombolytic therapies in acute myocardial infarction.” Am J Cardiol 73, no. 7 (March 1, 1994): 444–49. https://doi.org/10.1016/0002-9149(94)90673-4.
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• Ohman, E. M., J. F. Marquis, D. R. Ricci, R. I. Brown, M. L. Knudtson, D. J. Kereiakes, J. K. Samaha, J. R. Margolis, A. L. Niederman, and L. S. Dean. “A randomized comparison of the effects of gradual prolonged versus standard primary balloon inflation on early and late outcome. Results of a multicenter clinical trial. Perfusion Balloon Catheter Study Group.” Circulation 89, no. 3 (March 1994): 1118–25. https://doi.org/10.1161/01.cir.89.3.1118.
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• Friedman, H. S. “Thrombolytic therapy for acute myocardial infarction: GUSTO criticized.” N Engl J Med 330, no. 7 (February 17, 1994): 504. https://doi.org/10.1056/NEJM199402173300715.
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• Scheidt, S., A. A. J. Adgey, E. Braunwald, R. M. Califf, K. L. Neuhaus, A. M. Ross, E. J. Topol, and W. D. Weaver. “Thrombolytic therapy after GUSTO: Medical roundtable discussion.” Cardiovascular Reviews and Reports 15, no. 1 (January 28, 1994).
• Mark, D. B., L. C. Lam, K. L. Lee, R. H. Jones, D. B. Pryor, R. S. Stack, R. B. Williams, N. E. Clapp-Channing, R. M. Califf, and M. A. Hlatky. “Effects of coronary angioplasty, coronary bypass surgery, and medical therapy on employment in patients with coronary artery disease. A prospective comparison study.” Ann Intern Med 120, no. 2 (January 15, 1994): 111–17. https://doi.org/10.7326/0003-4819-120-2-199401150-00003.
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• Faxon, D. P., T. E. Spiro, S. Minor, G. Coté, J. Douglas, R. Gottlieb, R. Califf, et al. “Low molecular weight heparin in prevention of restenosis after angioplasty: Results of Enoxaparin restenosis (ERA) trial.” Circulation 90, no. 2 (1994): 908–14.
• Fuster, V., R. M. Califf, and J. H. Chesebro. “Reply.” The American Journal of Cardiology 73, no. 9 (1994): 725–26.
• Krucoff, M. W., C. L. Green, F. E. Harrell, M. L. Simoons, N. M. Wilderman, K. M. Trollinger, S. T. Sawchak, J. E. Pope, A. Shah, and C. B. Granger. “From signal/noise to information content/noise. Reconsidering the statistical analysis of continuous ST-segment data streams with gaps: potential optimization of application-specific information content using left, right, and interval censoring.” J Electrocardiol 27 Suppl (1994): 233–37. https://doi.org/10.1016/s0022-0736(94)80097-9.
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• Lambrew, C. T., M. S. Smith, G. G. Annas, R. R. Bass, J. Bracken, R. Califf, C. K. Francis, et al. “Emergency department: Rapid identification and treatment of patients with acute myocardial infarction.” Annals of Emergency Medicine 23, no. 2 (1994): 311–29.
• O’Connor, C. M., R. Meese, R. Carney, J. Smith, E. Conn, J. Burks, C. Hartman, S. Roark, N. Shadoff, and M. Heard. “A randomized trial of intravenous heparin in conjunction with anistreplase (anisoylated plasminogen streptokinase activator complex) in acute myocardial infarction: the Duke University Clinical Cardiology Study (DUCCS) 1.” J Am Coll Cardiol 23, no. 1 (January 1994): 11–18. https://doi.org/10.1016/0735-1097(94)90496-0.
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• Packer, M., M. Gheorghiade, J. B. Young, and R. M. Califf. “Withdrawal of digoxin after treatment of chronic heart failure.” Annals of Internal Medicine 120, no. 2 SUPPL. 1 (January 1, 1994).
• Ross, A. M., R. M. Califf, and E. J. Topol. “GUSTO: The principal investigators respond to the criticism.” Journal of Myocardial Ischemia 6, no. 1 (January 1, 1994): 11–16.
• Shah, A., C. L. Green, K. M. Trollinger, N. M. Wilderman, J. E. Pope, R. M. Califf, G. S. Wagner, and M. W. Krucoff. “Reassessing the clinical significance of ST-segment depression that occurs concomitantly with the ST-segment elevation during acute myocardial infarction with the use of continuous ST-segment analysis.” Journal of Electrocardiology 27 Suppl (January 1994): 256–59. https://doi.org/10.1016/s0022-0736(94)80101-0.
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• Topol, E. J., and R. M. Califf. “Scorecard cardiovascular medicine. Its impact and future directions.” Ann Intern Med 120, no. 1 (January 1, 1994): 65–70. https://doi.org/10.7326/0003-4819-120-1-199401010-00011.
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• Abel, R. M. “Coronary atherectomy versus angioplasty.” N Engl J Med 329, no. 25 (December 16, 1993): 1891–92.
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• Lincoff, A. M., R. M. Califf, S. G. Ellis, K. N. Sigmon, K. L. Lee, J. D. Leimberger, and E. J. Topol. “Thrombolytic therapy for women with myocardial infarction: is there a gender gap? Thrombolysis and Angioplasty in Myocardial Infarction Study Group.” J Am Coll Cardiol 22, no. 7 (December 1993): 1780–87. https://doi.org/10.1016/0735-1097(93)90757-r.
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• Bernardi, M. M., R. M. Califf, N. Kleiman, S. G. Ellis, and E. J. Topol. “Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7E3 glycoprotein IIb/IIIa platelet antibody. The TAMI Study Group.” Am J Cardiol 72, no. 15 (November 15, 1993): 1121–25. https://doi.org/10.1016/0002-9149(93)90979-m.
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• Ohman, E. M., E. J. Topol, R. M. Califf, E. R. Bates, S. G. Ellis, D. J. Kereiakes, B. S. George, J. K. Samaha, E. Kline, and K. N. Sigmon. “An analysis of the cause of early mortality after administration of thrombolytic therapy. The Thrombolysis Angioplasty in Myocardial Infarction Study Group.” Coron Artery Dis 4, no. 11 (November 1993): 957–64. https://doi.org/10.1097/00019501-199311000-00002.
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• Topol, E. J., R. M. Califf, and K. L. Lee. “The irony of biased editors who write editorials. GUSTO Investigators.” Br J Clin Pract 47, no. 6 (November 1993): 283–84.
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• Ohman, E. M., R. H. Christenson, R. M. Califf, B. S. George, J. K. Samaha, D. J. Kereiakes, S. J. Worley, T. C. Wall, E. Berrios, and K. N. Sigmon. “Noninvasive detection of reperfusion after thrombolysis based on serum creatine kinase MB changes and clinical variables. TAMI 7 Study Group. Thrombolysis and Angioplasty in Myocardial Infarction.” Am Heart J 126, no. 4 (October 1993): 819–26. https://doi.org/10.1016/0002-8703(93)90694-5.
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• GUSTO investigators, C. V. “An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.” N Engl J Med 329, no. 10 (September 2, 1993): 673–82. https://doi.org/10.1056/NEJM199309023291001.
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• Kleiman, N. S., E. M. Ohman, R. M. Califf, B. S. George, D. Kereiakes, F. V. Aguirre, H. Weisman, T. Schaible, and E. J. Topol. “Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study.” J Am Coll Cardiol 22, no. 2 (August 1993): 381–89. https://doi.org/10.1016/0735-1097(93)90041-x.
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• Krucoff, M. W., M. A. Croll, J. E. Pope, C. B. Granger, C. M. O’Connor, K. N. Sigmon, B. L. Wagner, J. A. Ryan, K. L. Lee, and D. J. Kereiakes. “Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion.” Circulation 88, no. 2 (August 1993): 437–46. https://doi.org/10.1161/01.cir.88.2.437.
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• Topol, E. J., F. Leya, C. A. Pinkerton, P. L. Whitlow, B. Hofling, C. A. Simonton, R. R. Masden, P. W. Serruys, M. B. Leon, and D. O. Williams. “A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease. The CAVEAT Study Group.” N Engl J Med 329, no. 4 (July 22, 1993): 221–27. https://doi.org/10.1056/NEJM199307223290401.
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• Stead, W. W., W. P. Bird, R. M. Califf, J. G. Elchlepp, W. E. Hammond, and T. R. Kinney. “The IAIMS at Duke University Medical Center: transition from model testing to implementation.” Md Comput 10, no. 4 (July 1993): 225–30.
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• Tenaglia, A. N., D. F. Fortin, D. J. Frid, L. H. Gardner, C. L. Nelson, J. E. Tcheng, R. S. Stack, and R. M. Califf. “Long-term outcome following successful reopening of abrupt closure after coronary angioplasty.” Am J Cardiol 72, no. 1 (July 1, 1993): 21–25. https://doi.org/10.1016/0002-9149(93)90212-u.
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• Harrison, J. K., R. M. Califf, L. H. Woodlief, D. Kereiakes, B. S. George, R. S. Stack, S. G. Ellis, K. L. Lee, W. O’Neill, and E. J. Topol. “Systolic left ventricular function after reperfusion therapy for acute myocardial infarction. Analysis of determinants of improvement. The TAMI Study Group.” Circulation 87, no. 5 (May 1993): 1531–41. https://doi.org/10.1161/01.cir.87.5.1531.
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• Chapman, G. D., E. M. Ohman, E. J. Topol, R. J. Candela, D. J. Kereiakes, J. Samaha, E. Berrios, K. S. Pieper, S. Y. Young, and R. M. Califf. “Minimizing the risk of inappropriately administering thrombolytic therapy (Thrombolysis and Angioplasty in Myocardial Infarction [TAMI] study group).” Am J Cardiol 71, no. 10 (April 1, 1993): 783–87. https://doi.org/10.1016/0002-9149(93)90824-v.
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• Granger, C. B., R. M. Califf, S. Young, R. Candela, J. Samaha, S. Worley, D. J. Kereiakes, and E. J. Topol. “Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.” J Am Coll Cardiol 21, no. 4 (March 15, 1993): 920–25. https://doi.org/10.1016/0735-1097(93)90348-5.
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• Dudley, R. A., F. E. Harrell, L. R. Smith, D. B. Mark, R. M. Califf, D. B. Pryor, D. Glower, J. Lipscomb, and M. Hlatky. “Comparison of analytic models for estimating the effect of clinical factors on the cost of coronary artery bypass graft surgery.” J Clin Epidemiol 46, no. 3 (March 1993): 261–71. https://doi.org/10.1016/0895-4356(93)90074-b.
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• Wall, T. C., R. M. Califf, S. G. Ellis, K. Sigmon, D. Kereiakes, B. S. George, J. Samaha, D. Sane, D. C. Stump, and R. S. Stack. “Lack of impact of early catheterization and fibrin specificity on bleeding complications after thrombolytic therapy. The TAMI Study Group.” J Am Coll Cardiol 21, no. 3 (March 1, 1993): 597–603. https://doi.org/10.1016/0735-1097(93)90090-n.
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• Ellis, S. G., J. E. Tcheng, F. I. Navetta, D. W. Muller, H. F. Weisman, C. Smith, K. M. Anderson, R. M. Califf, and E. J. Topol. “Safety and antiplatelet effect of murine monoclonal antibody 7E3 Fab directed against platelet glycoprotein IIb/IIIa in patients undergoing elective coronary angioplasty.” Coron Artery Dis 4, no. 2 (February 1993): 167–75. https://doi.org/10.1097/00019501-199302000-00007.
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• Krucoff, M. W., M. A. Croll, J. E. Pope, K. S. Pieper, P. M. Kanani, C. B. Granger, R. F. Veldkamp, B. L. Wagner, S. T. Sawchak, and R. M. Califf. “Continuously updated 12-lead ST-segment recovery analysis for myocardial infarct artery patency assessment and its correlation with multiple simultaneous early angiographic observations.” Am J Cardiol 71, no. 2 (January 15, 1993): 145–51. https://doi.org/10.1016/0002-9149(93)90729-v.
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• Pryor, D. B., L. Shaw, C. B. McCants, K. L. Lee, D. B. Mark, F. E. Harrell, L. H. Muhlbaier, and R. M. Califf. “Value of the history and physical in identifying patients at increased risk for coronary artery disease.” Ann Intern Med 118, no. 2 (January 15, 1993): 81–90. https://doi.org/10.7326/0003-4819-118-2-199301150-00001.
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• Califf, R. M. “Morbidity and mortality after first myocardial infarction.” Annals of Internal Medicine 118, no. 6 SUPPL. (January 1, 1993).
• Sane, D. C., R. M. Califf, K. N. Sigmon, E. J. Topol, and D. C. Stump. “Effect of heparin administration on fibrinogenolysis during thrombolytic therapy with tissue plasminogen activator for acute myocardial infarction.” Fibrinolysis and Proteolysis 7, no. 2 (January 1, 1993): 103–7. https://doi.org/10.1016/0268-9499(93)90030-Y.
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• Scheidt, S., A. A. J. Adgey, R. M. Califf, K. L. Neuhaus, A. M. Ross, E. J. Topol, W. D. Weaver, and R. Wilcox. “Waiting for GUSTO: Current status of thrombolytic therapy. Medical panel discussion.” Cardiovascular Reviews and Reports 14, no. 3 (January 1, 1993): 26–57.
• Silva, P., M. Galli, L. Campolo, and R. M. Califf. “Early ischemia after myocardial infarction in low-risk patients.” Annals of Internal Medicine 119, no. SUPPL. 3 (January 1, 1993).
• Simoons, M. L., A. P. Maggioni, G. Knatterud, J. D. Leimberger, P. D. Jaegere, R. V. Domburg, E. Boersma, et al. “Individual risk assessment for intracranial haemorrhage during thrombolytic therapy.” Lancet 342, no. 8886–8887 (1993): 1523–28. https://doi.org/10.1016/S0140-6736(05)80089-3.
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• Tcheng, J. E., J. D. Jackman, C. L. Nelson, L. H. Gardner, L. R. Smith, J. S. Rankin, R. M. Califf, and R. S. Stack. “Does reperfusion improve prognosis when mitral regurgitation complicates infarction?” Cardiology Board Review 10, no. 8 (January 1, 1993): 17–22.
• Tcheng, J. E., J. D. Jackman, R. M. Califf, and R. S. Stack. “Managing myocardial infarction complicated by mitral regurgitation.” Primary Cardiology 19, no. 10 (January 1, 1993): 40–48.
• Topol, E. J., R. M. Califf, and K. L. Lee. “The irony of biased editors who write editorials.” British Journal of Clinical Practice 47, no. 6 (January 1, 1993): 283–84.
• Veldkamp, R. F., J. E. Pope, S. T. Sawchak, G. S. Wagner, R. M. Califf, and M. W. Krucoff. “ST-segment recovery as an endpoint in acute myocardial infarction trials. Past, present, and future.” J Electrocardiol 26 Suppl (1993): 256–61.
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• Bengtson, J. R., A. J. Kaplan, K. S. Pieper, N. M. Wildermann, D. B. Mark, D. B. Pryor, H. R. Phillips, and R. M. Califf. “Prognosis in cardiogenic shock after acute myocardial infarction in the interventional era.” J Am Coll Cardiol 20, no. 7 (December 1992): 1482–89. https://doi.org/10.1016/0735-1097(92)90440-x.
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• Sugrue, D. D., R. J. Rodeheffer, M. B. Codd, R. M. Califf, and B. J. Gersh. “Survival after diagnosis of idiopathic dilated cardiomyopathy.” Annals of Internal Medicine 118, no. SUPPL. 1 (December 1, 1992).
• Collins, R., P. Sleight, and A. P. Maggioni. “The risk of stroke after thrombolytic therapy.” N Engl J Med 327, no. 21 (November 19, 1992): 1531–32. https://doi.org/10.1056/NEJM199211193272116.
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• Popma, J. J., R. M. Califf, S. G. Ellis, B. S. George, D. J. Kereiakes, J. K. Samaha, S. J. Worley, J. L. Anderson, D. Stump, and L. Woodlief. “Mechanism of benefit of combination thrombolytic therapy for acute myocardial infarction: a quantitative angiographic and hematologic study.” J Am Coll Cardiol 20, no. 6 (November 15, 1992): 1305–12. https://doi.org/10.1016/0735-1097(92)90241-e.
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• Mark, D. B., L. C. Lam, K. L. Lee, N. E. Clapp-Channing, R. B. Williams, D. B. Pryor, R. M. Califf, and M. A. Hlatky. “Identification of patients with coronary disease at high risk for loss of employment. A prospective validation study.” Circulation 86, no. 5 (November 1992): 1485–94. https://doi.org/10.1161/01.cir.86.5.1485.
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• Muhlbaier, L. H., D. B. Pryor, J. S. Rankin, L. R. Smith, D. B. Mark, R. H. Jones, D. D. Glower, F. E. Harrell, K. L. Lee, and R. M. Califf. “Observational comparison of event-free survival with medical and surgical therapy in patients with coronary artery disease. 20 years of follow-up.” Circulation 86, no. 5 Suppl (November 1992): II198–204.
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• Topol, E. J., and R. M. Califf. “Answers to complex questions cannot be derived from "simple" trials.” Br Heart J 68, no. 4 (October 1992): 348–51. https://doi.org/10.1136/hrt.68.10.348.
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• Granger, Christopher B., Robert M. Califf, and Eric J. Topol. “Thrombolytic Therapy for Acute Myocardial Infarction : A Review.” Drugs 44, no. 3 (September 1992): 293–325. https://doi.org/10.2165/00003495-199244030-00002.
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• Sketch, M. H., P. J. Quigley, J. A. Perez, C. J. Davidson, J. B. Muhlestein, J. E. Herndon, D. D. Glower, H. R. Phillips, R. M. Califf, and R. S. Stack. “Angiographic follow-up after internal mammary artery graft angioplasty.” Am J Cardiol 70, no. 3 (August 1, 1992): 401–3. https://doi.org/10.1016/0002-9149(92)90632-9.
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• Topol, E. J., and R. M. Califf. “Thrombolytic therapy for elderly patients.” N Engl J Med 327, no. 1 (July 2, 1992): 45–47. https://doi.org/10.1056/NEJM199207023270109.
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• Tcheng, J. E., J. D. Jackman, C. L. Nelson, L. H. Gardner, L. R. Smith, J. S. Rankin, R. M. Califf, and R. S. Stack. “Outcome of patients sustaining acute ischemic mitral regurgitation during myocardial infarction.” Ann Intern Med 117, no. 1 (July 1, 1992): 18–24. https://doi.org/10.7326/0003-4819-117-1-18.
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• Topol, E. J., R. M. Califf, M. Vandormael, C. L. Grines, B. S. George, M. L. Sanz, T. Wall, M. O’Brien, M. Schwaiger, and F. V. Aguirre. “A randomized trial of late reperfusion therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction-6 Study Group.” Circulation 85, no. 6 (June 1992): 2090–99. https://doi.org/10.1161/01.cir.85.6.2090.
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• Bickell, N. A., K. S. Pieper, K. L. Lee, D. B. Mark, D. D. Glower, D. B. Pryor, and R. M. Califf. “Referral patterns for coronary artery disease treatment: gender bias or good clinical judgment?” Ann Intern Med 116, no. 10 (May 15, 1992): 791–97. https://doi.org/10.7326/0003-4819-116-10-791.
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• Topol, E. J., P. Armstrong, F. Van de Werf, N. Kleiman, K. Lee, D. Morris, M. Simoons, G. Barbash, H. White, and R. M. Califf. “Confronting the issues of patient safety and investigator conflict of interest in an international clinical trial of myocardial reperfusion. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO) Steering Committee.” J Am Coll Cardiol 19, no. 6 (May 1992): 1123–28. https://doi.org/10.1016/0735-1097(92)90312-b.
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• Topol, E. J., P. Armstrong, F. Van de Werf, N. Kleiman, K. Lee, D. Morris, M. Simoons, et al. “Confronting the issues of patient safety and investigator conflict of interest in an international clinical trial of myocardial reperfusion.” Journal of the American College of Cardiology 19, no. 6 (May 1, 1992): 1123–28.
• Califf, R. M., and E. M. Ohman. “The diagnosis of acute myocardial infarction.” Chest 101, no. 4 Suppl (April 1992): 106S-115S. https://doi.org/10.1378/chest.101.4_supplement.106s.
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• Ortel, T. L., J. P. Gockerman, R. M. Califf, R. L. McCann, C. M. O’Connor, D. M. Metzler, and C. S. Greenberg. “Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.” Thromb Haemost 67, no. 3 (March 2, 1992): 292–96.
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• Califf, R. M., and E. J. Topol. “Thrombolytic therapy for myocardial infarction: a perspective of clinical trialists. The GUSTO Investigators.” Clin Cardiol 15, no. 3 (March 1992): 143–44. https://doi.org/10.1002/clc.4960150303.
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• Wall, T. C., R. M. Califf, B. S. George, S. G. Ellis, J. K. Samaha, D. J. Kereiakes, S. J. Worley, K. Sigmon, and E. J. Topol. “Accelerated plasminogen activator dose regimens for coronary thrombolysis. The TAMI-7 Study Group.” J Am Coll Cardiol 19, no. 3 (March 1, 1992): 482–89. https://doi.org/10.1016/s0735-1097(10)80259-1.
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• O’Connor, C. M., and R. M. Califf. “Aggressive therapy of acute MI in the elderly.” Hosp Pract (Off Ed) 27, no. 2 (February 15, 1992): 59-passim. https://doi.org/10.1080/21548331.1992.11705360.
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• Califf, R. M., and C. Granger. “TIMI IIB follow-up. Lessons for clinicians and investigators.” Circulation 85, no. 2 (February 1992): 839–41. https://doi.org/10.1161/01.cir.85.2.839.
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• Sane, D. C., N. J. Gresalfi, L. A. Enney-O’Mara, R. M. Califf, C. S. Greenberg, E. G. Bovill, and B. J. Oberhardt. “Exploration of rapid bedside monitoring of coagulation and fibrinolysis parameters during thrombolytic therapy.” Blood Coagul Fibrinolysis 3, no. 1 (February 1992): 47–54. https://doi.org/10.1097/00001721-199202000-00008.
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• Williams, R. B., J. C. Barefoot, R. M. Califf, T. L. Haney, W. B. Saunders, D. B. Pryor, M. A. Hlatky, I. C. Siegler, and D. B. Mark. “Prognostic importance of social and economic resources among medically treated patients with angiographically documented coronary artery disease.” Jama 267, no. 4 (January 22, 1992): 520–24.
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• Califf, R. M., D. F. Fortin, A. N. Tenaglia, and D. C. Sane. “Clinical risks of thrombolytic therapy.” Am J Cardiol 69, no. 2 (January 3, 1992): 12A-20A. https://doi.org/10.1016/0002-9149(92)91168-4.
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• Califf, R. M. “Why are large-scale trials needed?” Coronary Artery Disease 3, no. 2 (January 1, 1992): 92–95. https://doi.org/10.1097/00019501-199202000-00002.
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• Califf, R. M., J. Popma, and E. J. Topol. “Small trials and new therapies [5].” Circulation 85, no. 4 (January 1, 1992): 1636–37.
• Califf, R. M., K. S. Pieper, W. R. Harlan, and K. L. Lee. “Serum cholesterol in patients undergoing cardiac catheterization for suspected coronary artery disease: diagnostic and prognostic implications.” Ann Epidemiol 2, no. 1–2 (January 1992): 137–45. https://doi.org/10.1016/1047-2797(92)90048-u.
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• Califf, R. M., and E. M. Ohman. “The diagnosis of acute myocardial infarction.” Chest 101, no. 4 SUPPL. (January 1, 1992). https://doi.org/10.1378/chest.101.4.106S.
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• Krucoff, M. W., M. Croll, J. Pope, J. Ryan, K. Pieper, S. Sawchak, B. Wagner, S. Crater, and R. Califf. “Unstable infarct artery. Quantification across angiographic subgroups using continuous digital 12-lead ST-segment recovery analysis.” J Electrocardiol 24 Suppl (1992): 15.
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• Muhlbaier, L. H., D. B. Pryor, J. S. Rankin, L. R. Smith, D. B. Mark, R. H. Jones, D. D. Glower, et al. “Observational comparison of event-free survival with medical and surgical therapy in patients with coronary artery disease: 20 Years of follow-up.” Circulation 86, no. 5 SUPPL. (January 1, 1992).
• Veldkamp, R. F., J. R. Bengtson, S. T. Sawchak, J. E. Pope, J. R. Mertens, D. W. Mortara, R. M. Califf, and M. W. Krucoff. “Evolution of an automated ST-segment analysis program for dynamic real-time, noninvasive detection of coronary occlusion and reperfusion.” J Electrocardiol 25 Suppl (1992): 182–87. https://doi.org/10.1016/0022-0736(92)90098-k.
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• Muller, D. W., E. J. Topol, S. G. Ellis, L. H. Woodlief, K. N. Sigmon, D. J. Kereiakes, B. S. George, S. J. Worley, J. K. Samaha, and H. Phillips. “Determinants of the need for early acute intervention in patients treated conservatively after thrombolytic therapy for acute myocardial infarction. TAMI-5 Study Group.” J Am Coll Cardiol 18, no. 7 (December 1991): 1594–1601. https://doi.org/10.1016/0735-1097(91)90490-z.
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• Nayak, P. R., V. Bhaktaram, P. K. Shetty, S. Sivaraman, G. R. Narayanan, and P. Pais. “Third World profile of racial differences in thrombolytic effects of streptokinase.” Circulation 84, no. 5 (November 1991): 2205–7.
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• Smith, L. R., F. E. Harrell, J. S. Rankin, R. M. Califf, D. B. Pryor, L. H. Muhlbaier, K. L. Lee, D. B. Mark, R. H. Jones, and H. N. Oldham. “Determinants of early versus late cardiac death in patients undergoing coronary artery bypass graft surgery.” Circulation 84, no. 5 Suppl (November 1991): III245–53.
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• Tenaglia, A. N., R. M. Califf, R. J. Candela, D. J. Kereiakes, E. Berrios, S. Y. Young, R. S. Stack, and E. J. Topol. “Thrombolytic therapy in patients requiring cardiopulmonary resuscitation.” Am J Cardiol 68, no. 10 (October 15, 1991): 1015–19. https://doi.org/10.1016/0002-9149(91)90488-7.
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• Nelson, C. L., J. E. Herndon, D. B. Mark, D. B. Pryor, R. M. Califf, and M. A. Hlatky. “Relation of clinical and angiographic factors to functional capacity as measured by the Duke Activity Status Index.” Am J Cardiol 68, no. 9 (October 1, 1991): 973–75. https://doi.org/10.1016/0002-9149(91)90423-i.
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• Wallis, D. E., W. E. Boden, R. Califf, M. H. Crawford, A. H. Hakki, A. S. Iskandrian, A. Labovitz, C. O’Connor, R. Sutton, and P. J. Scanlon. “Failure of adjuvant heparin to reduce myocardial ischemia in the early treatment of patients with unstable angina.” Am Heart J 122, no. 4 Pt 1 (October 1991): 949–54. https://doi.org/10.1016/0002-8703(91)90456-r.
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• Mark, D. B., L. Shaw, F. E. Harrell, M. A. Hlatky, K. L. Lee, J. R. Bengtson, C. B. McCants, R. M. Califf, and D. B. Pryor. “Prognostic value of a treadmill exercise score in outpatients with suspected coronary artery disease.” N Engl J Med 325, no. 12 (September 19, 1991): 849–53. https://doi.org/10.1056/NEJM199109193251204.
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• Hellstrom, H. R. “Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction.” Circulation 84, no. 3 (September 1991): 1454–55. https://doi.org/10.1161/01.cir.84.3.1454.
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• Popma, J. J., R. M. Califf, and E. J. Topol. “Clinical trials of restenosis after coronary angioplasty.” Circulation 84, no. 3 (September 1991): 1426–36. https://doi.org/10.1161/01.cir.84.3.1426.
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• White, H., D. Cross, and R. Norris. “Point of view: use of left ventricular function as prognostic factor.” Circulation 84, no. 3 (September 1991): 1452–53. https://doi.org/10.1161/01.cir.84.3.1452.
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• Kereiakes, D. J., R. M. Califf, B. S. George, S. Ellis, J. Samaha, R. Stack, L. H. Martin, S. Young, and E. J. Topol. “Coronary bypass surgery improves global and regional left ventricular function following thrombolytic therapy for acute myocardial infarction. TAMI Study Group.” Am Heart J 122, no. 2 (August 1991): 390–99. https://doi.org/10.1016/0002-8703(91)90991-p.
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• Jackman, J. D., F. I. Navetta, J. E. Smith, J. E. Tcheng, C. J. Davidson, H. R. Phillips, R. M. Califf, C. L. Nelson, L. H. Gardner, and R. S. Stack. “Percutaneous transluminal coronary angioplasty in octogenarians as an effective therapy for angina pectoris.” Am J Cardiol 68, no. 1 (July 1, 1991): 116–19. https://doi.org/10.1016/0002-9149(91)90724-y.
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• Califf, R. M., D. F. Fortin, D. J. Frid, W. R. Harlan, E. M. Ohman, J. R. Bengtson, C. L. Nelson, J. E. Tcheng, D. B. Mark, and R. S. Stack. “Restenosis after coronary angioplasty: an overview.” J Am Coll Cardiol 17, no. 6 Suppl B (May 1991): 2B-13B. https://doi.org/10.1016/0735-1097(91)90933-z.
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• Califf, R. M., E. J. Topol, R. S. Stack, S. G. Ellis, B. S. George, D. J. Kereiakes, J. K. Samaha, S. J. Worley, J. L. Anderson, and L. Harrelson-Woodlief. “Evaluation of combination thrombolytic therapy and timing of cardiac catheterization in acute myocardial infarction. Results of thrombolysis and angioplasty in myocardial infarction--phase 5 randomized trial. TAMI Study Group.” Circulation 83, no. 5 (May 1991): 1543–56. https://doi.org/10.1161/01.cir.83.5.1543.
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• Pryor, D. B., L. Shaw, F. E. Harrell, K. L. Lee, M. A. Hlatky, D. B. Mark, L. H. Muhlbaier, and R. M. Califf. “Estimating the likelihood of severe coronary artery disease.” Am J Med 90, no. 5 (May 1991): 553–62.
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• Mark, D. B., K. Sigmon, E. J. Topol, D. J. Kereiakes, D. B. Pryor, R. J. Candela, and R. M. Califf. “Identification of acute myocardial infarction patients suitable for early hospital discharge after aggressive interventional therapy. Results from the Thrombolysis and Angioplasty in Acute Myocardial Infarction Registry.” Circulation 83, no. 4 (April 1991): 1186–93. https://doi.org/10.1161/01.cir.83.4.1186.
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• Muller, D. W., E. J. Topol, S. G. Ellis, K. N. Sigmon, K. Lee, and R. M. Califf. “Multivessel coronary artery disease: a key predictor of short-term prognosis after reperfusion therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.” Am Heart J 121, no. 4 Pt 1 (April 1991): 1042–49. https://doi.org/10.1016/0002-8703(91)90661-z.
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• Sane, D. C., D. C. Stump, E. J. Topol, K. N. Sigmon, D. J. Kereiakes, B. S. George, S. J. Mantell, E. Macy, D. Collen, and R. M. Califf. “Correlation between baseline plasminogen activator inhibitor levels and clinical outcome during therapy with tissue plasminogen activator for acute myocardial infarction.” Thromb Haemost 65, no. 3 (March 4, 1991): 275–79.
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• Belkin, R. N., D. B. Mark, L. Aronson, H. Szwed, R. M. Califf, and J. Kisslo. “Pericardial effusion after intravenous recombinant tissue-type plasminogen activator for acute myocardial infarction.” Am J Cardiol 67, no. 6 (March 1, 1991): 496–500. https://doi.org/10.1016/0002-9149(91)90010-i.
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• Ohman, E. M., R. M. Califf, B. S. George, P. J. Quigley, D. J. Kereiakes, L. Harrelson-Woodlief, R. J. Candela, C. Flanagan, R. S. Stack, and E. J. Topol. “The use of intraaortic balloon pumping as an adjunct to reperfusion therapy in acute myocardial infarction. Th