Overview
I am a cardiologist with a clinical and research interest in heart failure (going from Failure to Function), including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps."
I serve our group as Chief of the Heart Failure Section.
I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.
I am the Co-Editor in Chief of the Journal of Cardiac Failure - The official journal of the Heart Failure Society of America.
My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:
I am a leading clinical trialist in both traditional and pragmatic studies having served as a trial leader for HEART-FID, TRANSFORM-HF and PARAGLIDE-HF.
I serve as a Co-PI for the FDA’s Research Triangle CERSI (Center of Excellence in Regulatory Science and Innovation).
I serve our group as Chief of the Heart Failure Section.
I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.
I am the Co-Editor in Chief of the Journal of Cardiac Failure - The official journal of the Heart Failure Society of America.
My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:
- Cardiometabolic disease
- Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure
- Phenotypic characterization and risk prognostication of patients with heart failure
- Role of surrogate and nonfatal endpoints in clinical heart failure trials
- Biomarkers in heart failure
- Novel pharmacological and non-pharmacological approaches to heart failure
- Improving site-based heart failure research
I am a leading clinical trialist in both traditional and pragmatic studies having served as a trial leader for HEART-FID, TRANSFORM-HF and PARAGLIDE-HF.
I serve as a Co-PI for the FDA’s Research Triangle CERSI (Center of Excellence in Regulatory Science and Innovation).
Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Cardiology,
Medicine
Associate Professor in Population Health Sciences
·
2020 - Present
Population Health Sciences,
Basic Science Departments
Member in the Duke Clinical Research Institute
·
2014 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Implementation of a Digital Patient Activation Tool to Engage Patients With Heart Failure in Intensification of Guideline-Directed Medical Therapies.
Journal Article Comput Inform Nurs · March 31, 2026 Heart failure with reduced ejection fraction treatment with quadruple therapy reduces hospitalizations and improves patient survival. Despite evidence-based recommendations to initiate and up-titrate guideline-directed medical therapy to target doses, a ga ... Full text Link to item CiteInfluenza vaccination in patients with heart failure: comprehensive review of evidence, challenges, and clinical implications.
Journal Article Heart Fail Rev · March 14, 2026 Full text Link to item CiteKidney Disease and Heart Failure: Recent Advances and Current Challenges: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Journal Article JACC Heart Fail · March 6, 2026 Heart failure (HF) and chronic kidney disease (CKD) frequently coexist, which elevates the risks of hospitalization, disease progression, and death. Despite advances in treating each condition independently, many challenges remain in diagnosing and managin ... Full text Link to item CiteRecent Grants
Safety and Efficacy of the Alleviant No-Implant Interatrial Shunt in Patients with Heart Failure and Reduced Ejection Fraction
Clinical TrialPrincipal Investigator · Awarded by Alleviant Medical, Inc. · 2025 - 2032The Iron Needed for Function and Undesirable Symptoms in Elderly with Heart Failure with Preserved Ejection Fraction (INFUSE-HFpEF)
ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2031Research Triangle Center of Excellence in Regulatory Science and Innovation
ResearchCo-Principal Investigator · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028View All Grants
Education
Emory University ·
2003
M.D.