Overview
I am a cardiologist with a clinical and research interest in heart failure (going from Failure to Function), including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps."
I serve our group as Chief of the Heart Failure Section.
I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.
I am the Editor in Chief of the Journal of Cardiac Failure - The official journal of the Heart Failure Society of America.
My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:
I serve our group as Chief of the Heart Failure Section.
I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.
I am the Editor in Chief of the Journal of Cardiac Failure - The official journal of the Heart Failure Society of America.
My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:
- Cardiometabolic disease
- Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure
- Phenotypic characterization and risk prognostication of patients with heart failure
- Role of surrogate and nonfatal endpoints in clinical heart failure trials
- Biomarkers in heart failure
- Novel pharmacological and non-pharmacological approaches to heart failure
- Improving site-based heart failure research
Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Cardiology,
Medicine
Associate Professor in Population Health Sciences
·
2020 - Present
Population Health Sciences,
Basic Science Departments
Member in the Duke Clinical Research Institute
·
2014 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Effects of angiotensin-neprilysin inhibition in women vs men: Insights from PARAGLIDE-HF.
Journal Article Am Heart J · October 2025 BACKGROUND: Sub-analyses of key trials suggest a preferential benefit for specific heart failure with preserved ejection fraction (HFpEF) therapies in women. This work investigated treatment effects between women and men in the PARAGLIDE-HF (Prospective co ... Full text Link to item CiteFDA's Focus on Post-Approval "Pragmatic Clinical Research": Reflections on Its Implementation.
Other Mayo Clin Proc · July 2025 Full text Link to item CiteA Beginner's Mind –Reflections for the Trainee Through the Retiree
Journal Article Journal of Cardiac Failure · July 1, 2025 Full text CiteRecent Grants
Research Triangle Center of Excellence in Regulatory Science and Innovation
ResearchCo-Principal Investigator · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028BalanceD-HF
Clinical TrialPrincipal Investigator · Awarded by AstraZeneca UK Limited · 2024 - 2027Physical Rehabilitation for Older Patients with Acute HFpEF-The REHAB-HFpEF Trial - Trial Administration
ResearchPrincipal Investigator · Awarded by Wake Forest University Health Sciences · 2022 - 2027View All Grants
Education, Training & Certifications
Emory University ·
2003
M.D.