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Victor Louis Roggli

Professor Emeritus of Pathology
Pathology
Duke Box 3712, Durham, NC 27710
M255 Davison Bldg, 200 Trent Drive, Durham, NC 27710

Scholarly Works - Book sections


Carcinoma of the Lung

Book section · January 1, 2025 Carcinoma of the lung is the number one cause of cancer mortality in the United States. The primary cause of this highly fatal malignancy is cigarette smoking, which accounts for at least 85% of cases. Asbestos is a contributing factor in a small percentag ... Full text Cite

Asbestos Bodies and Non-asbestos Ferruginous Bodies

Book section · January 1, 2025 Biopersistent mineral fibers deposited in the lower respiratory tract that measure 15–20 microns or greater in length are taken up by alveolar macrophages. In a process referred to as frustrated phagocytosis, these macrophages coat the fibers with an iron ... Full text Cite

Analysis of Tissue Mineral Fiber Content

Book section · January 1, 2025 Mineral fibers may be identified in the lungs of most individuals from industrialized societies. When present in excessive amounts, the accumulation of these fibers may result in several diseases. At lower levels, there is an increased risk of mesothelioma ... Full text Cite

Pneumoconioses

Book section · January 1, 2022 This chapter discusses major forms of inhalational dust-related and occupational lung disease (pneumoconiosis). ... Full text Cite

Lung cancer: Clinical findings, pathology, and exposure assessment

Book section · January 1, 2020 Lung cancer is the most common malignancy worldwide and the most common cause of a cancer-related death. Tobacco smoking is the most important cause of lung cancer in most populations although occupational exposures cause an increased risk of lung cancer m ... Full text Cite

Occupations With Exposure to Crystalline Silica

Book section · January 1, 2018 This chapter discusses major forms of inhalational dust-related and occupational lung disease (pneumoconiosis). ... Full text Cite

Pneumoconioses

Book section · October 20, 2017 This chapter discusses major forms of inhalational dust-related and occupational lung disease (pneumoconiosis). ... Full text Cite

Mesothelioma Pathology

Book section · 2017 Cite

Lung cancer (exposure assessment, pathology, and epidemiology)

Book section · January 1, 2014 Lung cancer is the most common malignancy worldwide and the most common cause of a cancer-related death. Tobacco smoking is the most important cause of lung cancer in most populations although occupational exposures cause an increased risk of lung cancer m ... Full text Cite

Analysis of tissue mineral fiber content

Book section · January 1, 2014 The development of techniques for assaying the mineral fiber content of tissues has provided the opportunity to correlate the occurrence of various fiber-related diseases with the cumulative fiber burdens in the target organ. Exposure to mineral fibers gen ... Full text Cite

Asbestosis

Book section · January 1, 2014 The term pneumoconiosis dates to Zenker’s 1866 description of pulmonary disease processes related to the inhalation of dusts [1]. As some dust, including asbestos fibers, may be found in the lungs of virtually all adults from the general population, pneumo ... Full text Cite

Asbestos bodies and non-asbestos ferruginous bodies

Book section · January 1, 2014 The development of techniques for assaying the mineral fiber content of tissues has provided the opportunity to correlate the occurrence of various fiber-related diseases with the cumulative fiber burdens in the target organ. Exposure to mineral fibers gen ... Full text Cite

Carcinoma of the lung

Book section · January 1, 2014 During the past 50 years, the USA and other industrialized nations have witnessed a remarkable increase in mortality from carcinoma of the lung. Today, this disease is the number one cause of cancer mortality in the USA, accounting for more than 180,000 de ... Full text Cite

Occupational lung disease

Book section · January 1, 2012 Introduction Occupational lung disease is the most significant form of work-related illness in the United States in terms of its severity, frequency and cost to society. The US Department of Labor reported the occurrence of some 4.1 million workplace injur ... Full text Cite

Electron Microscopy in Occupational and Environmental Lung Disease

Book section · January 1, 2012 This chapter contains sections titled: Introduction Asbestos Hypersensitivity Pneumonitis and Sarcoidosis Silicosis Silicate Pneumoconiosis Metal-Induced Diseases Rare-Earth Pneumoconiosis Miscellaneous Disorders References. ... Full text Cite

Pneumoconioses

Book section · January 1, 2011 Full text Cite

Pneumoconioses

Book section · January 1, 2011 Full text Cite

Predominantly mature interstitial fibrosis

Book section · January 1, 2008 Cite