Ryan Meyerhoff | Scholars@Duke

Ryan Meyerhoff
House Staff

Program Start Year: 2013
Barton Haynes Laboratory

"Studies of Immunogens to Induce Broadly Neutralizing HIV Antibodies"

Current Appointments & Affiliations

House Staff, Immunology, Basic Science Departments
House Staff, Surgery, Clinical Science Departments

Contact Information

MSRB II 106 Research Drive, Box 103020, Durham, NC 27710
ryan.meyerhoff@duke.edu +1 919 684 3045

Research
Selected Grants
- Novel mouse model of HIV broad neutralizing antibody induction awarded by National Institutes of Health 2016 - 2017
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Yang, Chi-Fu Jeffrey, Sai Yendamuri, Nicholas R. Mayne, Athar Battoo, Hanghang Wang, R Ryan Meyerhoff, Keith Vandusen, et al. “The role of thoracoscopic pneumonectomy in the management of non-small cell lung cancer: A multicenter study.” J Thorac Cardiovasc Surg 158, no. 1 (July 2019): 252-264.e2. https://doi.org/10.1016/j.jtcvs.2018.12.001.
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  - Yang, Chi-Fu Jeffrey, Kelli Aibel, Ryan Meyerhoff, Frances Wang, David Harpole, Amy P. Abernethy, and Thomas W. LeBlanc. “Actigraphy assessment of sleep quality among patients with acute myeloid leukaemia during induction chemotherapy.” Bmj Support Palliat Care 8, no. 3 (September 2018): 274–77. https://doi.org/10.1136/bmjspcare-2018-001509.
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  - Wiehe, Kevin, Todd Bradley, R Ryan Meyerhoff, Connor Hart, Wilton B. Williams, David Easterhoff, William J. Faison, et al. “Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.” Cell Host Microbe 23, no. 6 (June 13, 2018): 759-765.e6. https://doi.org/10.1016/j.chom.2018.04.018.
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  - Fera, Daniela, Matthew S. Lee, Kevin Wiehe, R Ryan Meyerhoff, Alessandro Piai, Mattia Bonsignori, Baptiste Aussedat, et al. “HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.” Nat Commun 9, no. 1 (March 16, 2018): 1111. https://doi.org/10.1038/s41467-018-03565-6.
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  - Meyerhoff, R Ryan, Richard M. Scearce, Damon F. Ogburn, Brad Lockwood, Joy Pickeral, Masa Kuraoka, Kara Anasti, et al. “HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies.” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 859–68. https://doi.org/10.1089/AID.2016.0294.
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  - Alam, S Munir, Baptiste Aussedat, Yusuf Vohra, R Ryan Meyerhoff, Evan M. Cale, William E. Walkowicz, Nathan A. Radakovich, et al. “Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.” Sci Transl Med 9, no. 381 (March 15, 2017). https://doi.org/10.1126/scitranslmed.aai7521.
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  - Bonsignori, Mattia, Edward F. Kreider, Daniela Fera, R Ryan Meyerhoff, Todd Bradley, Kevin Wiehe, S Munir Alam, et al. “Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.” Sci Transl Med 9, no. 381 (March 15, 2017). https://doi.org/10.1126/scitranslmed.aai7514.
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  - Saunders, Kevin O., Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R Ryan Meyerhoff, Robert Parks, William E. Walkowicz, et al. “Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.” Cell Rep 18, no. 9 (February 28, 2017): 2175–88. https://doi.org/10.1016/j.celrep.2017.02.003.
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  - Yang, Chi-Fu Jeffrey, Brandon W. Yan, Robert Ryan Meyerhoff, Shakir M. Saud, Brian C. Gulack, Paul J. Speicher, Matthew G. Hartwig, Thomas A. D’Amico, David H. Harpole, and Mark F. Berry. “Impact of Age on Long-Term Outcomes of Surgery for Malignant Pleural Mesothelioma.” Clin Lung Cancer 17, no. 5 (September 2016): 419–26. https://doi.org/10.1016/j.cllc.2016.03.002.
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  - Yang, Chi-Fu Jeffrey, Nicholas R. Mayne, Hanghang Wang, Ryan R. Meyerhoff, Sameer Hirji, Betty C. Tong, Matthew Hartwig, David Harpole, Thomas A. D’Amico, and Mark Berry. “Outcomes of Major Lung Resection After Induction Therapy for Non-Small Cell Lung Cancer in Elderly Patients.” Ann Thorac Surg 102, no. 3 (September 2016): 962–70. https://doi.org/10.1016/j.athoracsur.2016.03.088.
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  - Yang, Chi-Fu Jeffrey, Robert Ryan Meyerhoff, Nicholas Ryan Mayne, Terry Singhapricha, Christopher B. Toomey, Paul J. Speicher, Matthew G. Hartwig, et al. “Long-term survival following open versus thoracoscopic lobectomy after preoperative chemotherapy for non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1615–23. https://doi.org/10.1093/ejcts/ezv428.
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  - Yang, Chi-Fu Jeffrey, Syed M. Adil, Kevin L. Anderson, Robert Ryan Meyerhoff, Ryan S. Turley, Matthew G. Hartwig, David H. Harpole, et al. “Impact of patient selection and treatment strategies on outcomes after lobectomy for biopsy-proven stage IIIA pN2 non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1607–13. https://doi.org/10.1093/ejcts/ezv431.
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  - Meyerhoff, Robert Ryan, Chi-Fu Jeffrey Yang, Paul J. Speicher, Brian C. Gulack, Matthew G. Hartwig, Thomas A. D’Amico, David H. Harpole, and Mark F. Berry. “Impact of mesothelioma histologic subtype on outcomes in the Surveillance, Epidemiology, and End Results database.” J Surg Res 196, no. 1 (June 1, 2015): 23–32. https://doi.org/10.1016/j.jss.2015.01.043.
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  - Yang, Chi-Fu Jeffrey, R Ryan Meyerhoff, Sarah J. Stephens, Terry Singhapricha, Christopher B. Toomey, Kevin L. Anderson, Chris Kelsey, David Harpole, Thomas A. D’Amico, and Mark F. Berry. “Long-Term Outcomes of Lobectomy for Non-Small Cell Lung Cancer After Definitive Radiation Treatment.” Ann Thorac Surg 99, no. 6 (June 2015): 1914–20. https://doi.org/10.1016/j.athoracsur.2015.01.064.
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  - Moody, M Anthony, Sampa Santra, Nathan A. Vandergrift, Laura L. Sutherland, Thaddeus C. Gurley, Mark S. Drinker, Ashley A. Allen, et al. “Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques.” J Virol 88, no. 6 (March 2014): 3329–39. https://doi.org/10.1128/JVI.03309-13.
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  - Moody, M Anthony, Nicole L. Yates, Joshua D. Amos, Mark S. Drinker, Joshua A. Eudailey, Thaddeus C. Gurley, Dawn J. Marshall, et al. “HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.” J Virol 86, no. 14 (July 2012): 7496–7507. https://doi.org/10.1128/JVI.00426-12.
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  - Meyerhoff, R. R., R. A. Ali, K. Liu, G. -. Q. Huang, and M. D. Koci. “Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys.” Poultry Science 91, no. 2 (February 2012): 383–92. https://doi.org/10.3382/ps.2011-01846.
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  - Meyerhoff, R Ryan, Prashant K. Nighot, Rizwana A. Ali, Anthony T. Blikslager, and Matthew D. Koci. “Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection.” Comparative Immunology, Microbiology and Infectious Diseases 35, no. 1 (January 2012): 63–69. https://doi.org/10.1016/j.cimid.2011.10.002.
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  - Moody, M Anthony, Ruijun Zhang, Emmanuel B. Walter, Christopher W. Woods, Geoffrey S. Ginsburg, Micah T. McClain, Thomas N. Denny, et al. “H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination.” Plos One 6, no. 10 (2011): e25797. https://doi.org/10.1371/journal.pone.0025797.
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Selected Grants

Selected Publications

Academic Articles