Journal articleJ Laparoendosc Adv Surg Tech A · June 2026
INTRODUCTION: Appendectomies are common among pediatric patients. This study aimed to assess the safety and utility of a two-row stapler reload in pediatric appendectomies. METHODS: A prospective registry was used to collect study data at two U.S. centers ...
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Journal articleSurg Innov · May 8, 2026
Background/NeedLaparoscopic abdominal surgery requires navigating unique technical challenges with precision, dexterity, and a thorough understanding of anatomy. There is a need for higher-fidelity training models to assist in improving trainee competence. ...
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Journal articleSurg Endosc · March 2026
OBJECTIVE: To evaluate whether a low-cost, automated tool using trajectory-based metrics and real-time computer vision can objectively assess laparoscopic camera navigation (LCN) skill and distinguish between levels of surgical experience. Laparoscopic cam ...
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Journal articleJournal of Medical Robotics Research · January 1, 2026
Cervical cancer accounts for a significant portion of the global cancer burden among women. Interstitial brachytherapy (ISBT) is a standard procedure for treating cervical cancer; it involves placing a radioactive source through a straight hollow needle wi ...
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Journal articleJ Transl Med · December 24, 2025
BACKGROUND: Pancreatic acinar cell carcinoma (ACC) is a rare primary neoplasm of acinar cell origin. Histologically, it can present as pure ACC or mixed with neuroendocrine or ductal differentiation. We studied whether ACC shared genomic similarities with ...
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Journal articleJ Surg Educ · December 2025
OBJECTIVE: This study presents the results from a pilot faculty reciprocal peer coaching (FRPC) program within the colorectal surgery division at a single institution. DESIGN: This is a pre-post observational study of a group-based 3-hour FRPC robotic porc ...
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Journal articleAnn Surg Oncol · October 2025
BACKGROUND: Hepatic arterial infusion (HAI) chemotherapy is an expanding treatment for patients with unresectable colorectal liver metastases (uCRLM). This study examined circulating tumor DNA (ctDNA) as a novel biomarker to prognosticate oncologic outcome ...
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Journal articleCancer Immunol Immunother · August 23, 2025
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is characterized by exceedingly high rates of metastatic progression, with the liver representing the most common site of distant spread. Here, we established a platform for multisite immune profiling of ...
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Journal articleNeurosurg Focus Video · July 2025
A 50-year-old male with grade I spondylolisthesis at L5-S1 was treated surgically with a robotic anterior lumbar interbody fusion (R-ALIF). A general surgeon used the da Vinci robotic system to access the disc space and indocyanine green to visualize the v ...
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Journal articleJ Natl Compr Canc Netw · June 2025
BACKGROUND: The benefit of adjuvant chemotherapy (AC) for ampullary adenocarcinoma is unclear. The Hidden Genome model classifies prognostic subtypes with greater accuracy than standard histologic classification (intestinal [INT] vs pancreatobiliary [PB]), ...
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Journal articleBMC Surg · May 21, 2025
INTRODUCTION: Anterior Lumbar Interbody Fusion (ALIF) is a commonly performed spine surgery procedure used to treat lumbar conditions such as degenerative disc disease, spondylolisthesis, and spinal deformities. Traditionally, it has been performed using o ...
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Journal articleAnn Surg Oncol · May 2025
BACKGROUND: A growing number of centers offer hepatic artery infusion pump (HAIP) chemotherapy for advanced liver malignancies. While small series have demonstrated feasibility of robotic HAIP placement, comparison of outcomes with open placement is lackin ...
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Journal articleAnn Surg Oncol · April 2025
BACKGROUND: Randomized data suggest improved survival with adjuvant chemotherapy for biliary tract cancers; however, subset analyses of intrahepatic cholangiocarcinoma (IHC) show limited survival benefit. This study evaluated the impact of adjuvant chemoth ...
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Journal articleAnn Surg Oncol · March 2025
BACKGROUND: Pancreatic acinar cell carcinoma (pACC) is a rare neoplasm of the exocrine pancreas. There is a dearth of information about tumor characteristics and patient outcomes. This study describes the clinical characteristics, genetic alterations, and ...
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Journal articleSurgical Oncology Insight · March 1, 2025
Background: Gallbladder cancer (GBC) portends a poor prognosis, and guidelines recommend radical cholecystectomy for patients with T1b and greater disease. We evaluated prognostic factors for T2 and T3 GBC among a contemporary cohort. Methods: The National ...
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Journal articleJAMA Surg · December 1, 2024
IMPORTANCE: Ampullary adenocarcinoma (AA) is characterized by clinical and genomic heterogeneity. A previously developed genomic classifier defined biologically distinct phenotypes with greater accuracy than standard histologic classification. External val ...
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Journal articleAnn Surg · November 1, 2024
OBJECTIVE: To determine the interobserver variability for complications of pancreatoduodenectomy as defined by the International Study Group for Pancreatic Surgery (ISGPS) and others. BACKGROUND: Good interobserver variability for the definitions of surgic ...
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Journal articleAnn Surg Oncol · November 2024
INTRODUCTION: Desmoid tumors (DTs) are rare, fibroblastic cell proliferations that can exhibit locally aggressive behavior but lack metastatic potential. Initial management has traditionally involved upfront resection; however, contemporary guidelines and ...
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Journal articleInt J Surg · November 1, 2024
BACKGROUND: Surgical resection is a curative therapy for early-stage hepatocellular carcinoma (HCC) patients meeting the Milan criteria as well as a widely used therapy in intermediate-stage HCC. However, intermediate-stage HCC encompasses a wide spectrum ...
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Journal articleJ Surg Res · November 2024
INTRODUCTION: Development of technical skills is a vital component of surgical residency. The use of animal tissues for operative simulation leads to both the loss of animal life and financial costs for the institution. We hypothesized that maximizing tiss ...
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Journal articleSurgical Oncology Insight · September 1, 2024
Introduction: Approximately 5 % of patients with new breast cancer diagnoses have stage IV disease and 10 % of these patients have liver-confined metastases. The surgical management of synchronous liver metastases remains controversial. Methods: The Nation ...
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Journal articleJ Hepatobiliary Pancreat Sci · May 2024
BACKGROUND: This meta-analysis investigated the effects of enhanced recovery after surgery (ERAS) protocols compared to conventional care on postoperative outcomes in patients aged 70 years or older undergoing pancreatoduodenectomy (PD). METHODS: Five data ...
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Journal articleJ Gastrointest Surg · May 2024
BACKGROUND: Liver transplantation (LT) has been shown to be superior to resection in highly selected patients with perihilar cholangiocarcinoma (CCA), yet has traditionally been contraindicated for intrahepatic CCA (iCCA). Herein, we aimed to examine conte ...
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Journal articleHPB (Oxford) · April 2024
BACKGROUND: Radical cholecystectomy is recommended for T1B and greater gallbladder cancer, however, there are conflicting reports on the utility of extended resection for T1B disease. Herein, we characterize outcomes following simple and radical cholecyste ...
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Journal articleJ Robot Surg · March 16, 2024
Robotic pancreaticoduodenectomy (RPD) has a learning curve of approximately 30-250 cases to reach proficiency. The learning curve for laparoscopic pancreaticoduodenectomy (LPD) at Duke University was previously defined as 50 cases. This study describes the ...
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Journal articleJ Surg Oncol · December 2023
OBJECTIVES: We performed a retrospective analysis within a national cancer registry on outcomes following resection or ablation for intrahepatic cholangiocarcinoma (iCCA). METHODS: The National Cancer Database was queried for patients with clinical stage I ...
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Journal articleSurg Endosc · November 2023
BACKGROUND: Transparency around surgeon level data may align healthcare delivery with quality care for patients. Biliary surgery includes numerous procedures performed by both general surgeons and subspecialists alike. Cholecystectomy is a common surgical ...
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Journal articleAnn Surg Oncol · October 2023
BACKGROUND: Hepatectomy is the cornerstone of curative-intent treatment for intrahepatic cholangiocarcinoma (ICC). However, in patients unable to be resected, data comparing efficacy of alternatives including thermal ablation and radiation therapy (RT) rem ...
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Journal articleHPB (Oxford) · October 2023
BACKGROUND: Literature is lacking on the impact of advancements in minimally invasive surgery (MIS) on outcomes for patients with gastroenteropancreatic neuroendocrine carcinomas (GEP-NECs). Herein, we compared perioperative and oncologic outcomes among pa ...
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Journal articleJ Vasc Surg Cases Innov Tech · September 2023
Management of pancreaticoduodenal artery aneurysms (PDAAs) and gastroduodenal artery aneurysms (GDAAs) with concomitant celiac occlusion represents a challenging clinical scenario. Here, we describe a 62-year-old female with PDAA and GDAA complicated by ce ...
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Journal articleAnn Surg · August 1, 2023
BACKGROUND AND OBJECTIVE: Robotic distal pancreatectomy (DP) is an emerging attractive approach, but its role compared with laparoscopic or open surgery remains unclear. Benchmark values are novel and objective tools for such comparisons. The aim of this s ...
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Journal articleAnn Surg Oncol · August 2023
BACKGROUND: Resection remains the cornerstone of curative-intent treatment for biliary tract cancers (BTCs). However, recent randomized data also support a role for adjuvant chemotherapy (AC). This study aimed to characterize trends in the use of AC and su ...
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Journal articleSurgery · August 2023
Patients with unresectable colorectal liver metastases are commonly treated with systemic chemotherapy to convert their disease to an operable state. Unfortunately, many patients remain unresectable after first-line chemotherapy and resort to second- and t ...
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Journal articleSurg Open Sci · August 2023
BACKGROUND: Proficiency in ultrasound usage is quickly becoming an expectation in multiple residency programs: emergency medicine, obstetrics-gynecology, surgery, and internal medicine. There is a lack of affordable training devices for ultrasound training ...
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Journal articleJ Am Coll Surg · April 1, 2023
BACKGROUND: Despite institutional perioperative bundles and national infection prevention guidelines, surgical site infection (SSI) after a major abdominal operation remains a significant source of morbidity. Negative pressure therapy (NPT) has revolutioni ...
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Journal articleAnn Surg · December 1, 2022
BACKGROUND: Hepatic artery infusion (HAI) is a liver-directed therapy that delivers high-dose chemotherapy to the liver through the hepatic arterial system for colorectal liver metastases and intrahepatic cholangiocarcinoma. Utilization of HAI is rapidly e ...
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Journal articleHPB (Oxford) · July 2022
BACKGROUND: Standard of care for resectable pancreatic cancer is a combination of surgical resection (SR) and multiagent chemotherapy (MCT). We aim to determine whether SR or MCT is associated with superior survival for patients receiving only single-modal ...
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Journal articleJ Gastrointest Surg · April 2022
BACKGROUND: Colorectal liver metastases (CRLM) are the most common cause of disease-specific mortality in patients with colorectal cancer. Hepatic artery infusion (HAI) combined with systemic chemotherapy improves survival for these patients. The safety of ...
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Journal articleJ Am Coll Surg · April 1, 2022
BACKGROUND: This prospective study was designed to compare quality of life (QoL) among patients who underwent open (O-PD) vs minimally invasive pancreaticoduodenectomy (MI-PD), using a combination of validated qualitative and quantitative methodologies. ST ...
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Journal articleBr J Surg · February 24, 2022
BACKGROUND: This individual-patient data meta-analysis investigated the effects of enhanced recovery after surgery (ERAS) protocols compared with conventional care on postoperative outcomes in patients undergoing pancreatoduodenectomy. METHODS: The Cochran ...
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Journal articleAnn Clin Transl Neurol · February 2022
OBJECTIVE: Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cereb ...
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Journal articleHPB (Oxford) · December 2021
BACKGROUND: The aim of the present study was to evaluate the impact of routine NGT decompression after PD on postoperative outcomes in the era of an enhanced recovery after surgery (ERAS) protocol. MATERIALS AND METHODS: A retrospective review of all patie ...
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Journal articleRadiology · December 2021
Background Current imaging methods for prediction of complete margin resection (R0) in patients with pancreatic ductal adenocarcinoma (PDAC) are not reliable. Purpose To investigate whether tumor-related and perivascular CT radiomic features improve preope ...
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Journal articleLancet Oncol · November 2021
BACKGROUND: Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during ...
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Journal articleJ Am Coll Surg · September 2021
BACKGROUND: Hepatopancreatobiliary (HPB) Fellowship training in the Americas consists of 3 distinctive routes with variable curricula: Surgical Oncology Fellowship via the Society of Surgical Oncology (SSO), Abdominal Transplant Surgery Fellowship via the ...
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Journal articleAnn Surg Open · March 2021
The history of modern American surgery is marked by larger-than-life pioneers who have made transformative contributions to our field. These extraordinary individuals have been known primarily for their technical and clinical mastery, development of novel ...
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Journal articleCancers (Basel) · February 1, 2021
The scope of our study was to compare the predictive ability of American Joint Committee on Cancer (AJCC) 7th and 8th edition in gallbladder carcinoma (GBC) patients, investigate the effect of AJCC 8th nodal status on the survival, and identify risk factor ...
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Journal articleBr J Surg · January 27, 2021
BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer sur ...
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Journal articleAnn Surg Oncol · December 2020
BACKGROUND: Hepatic artery infusion (HAI) combined with systemic chemotherapy is a treatment strategy for patients with unresectable liver-only or liver-dominant colorectal liver metastases (CRLM). Although HAI has previously been performed in only a few c ...
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Journal articleHPB (Oxford) · November 2020
BACKGROUND: Adjuvant chemotherapy (AC) is associated with improved survival following resection of pancreatic adenocarcinoma but is frequently delayed or deferred due to perioperative complications or patient deconditioning. The aim of this study was to as ...
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Journal articleJ Vasc Interv Radiol · July 2020
PURPOSE: To retrospectively compare technical success and major complication rates of laparoscopically versus radiologically inserted jejunostomy tubes. MATERIALS AND METHODS: In this single-institution retrospective study, 115 patients (60 men; mean age, ...
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Journal articleJ Alzheimers Dis · 2020
BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ...
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Journal articleHPB (Oxford) · December 2019
BACKGROUND: Approximately 38% of patients with colorectal cancer will develop isolated liver metastases. Sidedness of colon tumor is identified in non-metastatic and unresected metastatic cancers as predictive of survival, yet its dedicated analysis in res ...
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Journal articleSurg Technol Int · November 10, 2019
INTRODUCTION: Robotic-assisted surgery continues to evolve. Technical advantages are reported for intracorporal suturing, a technique with a long learning curve in conventional laparoscopy. The success of laparoscopic fundoplication relies on precise sutur ...
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Journal articleJ Robot Surg · June 2019
This retrospective study was performed to evaluate the safety and feasibility of the new Senhance robotic system (Transenterix) for robotic cholecystectomy. Our series is the first experience with cholecystectomies utilizing this new platform. From May 201 ...
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Journal articleSurg Technol Int · May 15, 2019
INTRODUCTION: This retrospective study was performed to evaluate the safety and feasibility of the new Senhance Robotic System (TransEnterix Inc., Morrisville, North Carolina) for inguinal hernia repairs using the transabdominal preperitoneal approach. MAT ...
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Journal articleJ Am Geriatr Soc · April 2019
BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ...
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Journal articleJ Surg Educ · 2019
OBJECTIVE: The purpose of this research is to study the early stages of the Senhance learning curve to report how force feedback impacts learning rate. This serves as an exploratory investigation into assumptions that fellows and faculty will adjust faster ...
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Journal articleJ BUON · 2019
PURPOSE: Review of the literature collecting trials comparing laparoscopic (LGD2) and open D2 gastrectomies (OGD2) for the treatment of advanced gastric cancer (AGC). METHODS: Randomized control trials (RCTs) and non-RCTs comparing LGD2 with OGD2 for AGC t ...
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Journal articleSurgical Technology International · January 1, 2019
Introduction: This retrospective study was performed to evaluate the safety and feasibility of the new Sen-hance ™ Robotic System (TransEnterix Inc., Morrisville, North Carolina) for inguinal hernia repairs using the transabdominal preperitoneal approach. ...
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Journal articleSurgical Technology International · January 1, 2019
Introduction: Robotic-assisted surgery continues to evolve. Technical advantages are reported for intracor-poral suturing, a technique with a long learning curve in conventional laparoscopy. The success of laparoscopic fundoplication relies on precise sutu ...
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Journal articleAnnu Int Conf IEEE Eng Med Biol Soc · July 2018
In this study the complexity of the speed power spectrum is assessed as a metric for measuring trajectory smoothness. There are a variety of published methods for analyzing trajectory smoothness but many lack validity. This preliminary study took an inform ...
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Journal articleJ Surg Case Rep · February 2018
Use of ventricular assist devices (VADs) is increasingly common, as is the need for surgeons to be familiar with the management of common complications in this population. Nonetheless, repair of diaphragmatic hernias which commonly develop following VAD im ...
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Journal articleSurg Endosc · August 2017
BACKGROUND: Outcomes of surgical trials hinge on surgeon selection and their underlying expertise. Assessment of expertise is paramount. We investigated whether surgeons' performance measured by the fundamentals of laparoscopic surgery (FLS) assessment pro ...
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Journal articleAnn Surg · January 2017
BACKGROUND: Minimally invasive inguinal lymph node dissection (MILND) is a novel approach to inguinal lymphadenectomy. SAFE-MILND (NCT01500304) is a multicenter, phase I/II clinical trial evaluating the safety and feasibility of MILND for patients with mel ...
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Journal articleJ Am Coll Surg · March 2016
BACKGROUND: Minimally invasive inguinal lymphadenectomy (MILND) is a novel procedure with the potential to decrease surgical morbidity compared with the traditional open approach. The current study examined the feasibility of a combined didactic and hands- ...
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Journal articleAnn Surg · February 25, 2016
BACKGROUND: Minimally invasive inguinal lymph node dissection (MILND) is a novel approach to inguinal lymphadenectomy. SAFE-MILND (NCT01500304) is a multicenter, phase I/II clinical trial evaluating the safety and feasibility of MILND for patients with mel ...
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Journal articleAbdom Imaging · October 2015
Disease involving the pancreas can be a significant diagnostic challenge to the interpreting radiologist. Moreover, the majority of disease processes involving the pancreas carry high significant morbidity and mortality either due to their natural process ...
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Journal articleJ Surg Res · July 2015
BACKGROUND: Despite the established superiority of laparoscopic cholecystectomy (LC) for acute cholecystitis, gangrenous cholecystitis (GC) is commonly treated with open cholecystectomy (OC). This study aimed to characterize outcomes of GC in the modern er ...
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Journal articleSAGE Open Med Case Rep · 2015
While there is some local variability in the use of inferior vena cava filters and there has been some evolution in the indications for filter placement over time, inferior vena cava filters remain a standard option for pulmonary embolism prophylaxis. Indi ...
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Journal articleHPB (Oxford) · December 2014
INTRODUCTION: The drive to improve outcomes and the inevitability of mandated public reporting necessitate uniform documentation and accurate databases. The reporting of wound classification in patients undergoing hepato-pancreatico-biliary (HPB) surgery a ...
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Journal articleJ Surg Oncol · March 2013
BACKGROUND: The treatment of metastatic colorectal cancer (CRC) has evolved rapidly over the last decade, with combination chemotherapy and targeted biologic agents leading to significant improvements in survival. Despite these advances, little is known ab ...
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Journal articleOncology (Williston Park) · November 15, 2011
Historically, liver-related metastases associated with melanoma or breast cancer have portended a poor prognosis. Many affected patients are not considered for surgical resection based on the extent and multifocal nature of their disease. For this patient ...
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Journal articleGynecol Oncol Case Rep · 2011
► Patients diagnosed with granulosa cell tumor require long-term surveillance. ► Recurrent granulosa cell tumor may present as spontaneous retroperitoneal hemorrhage. ► We present an unusual case of recurrent granulosa cell tumor resulting in retroperitone ...
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Journal articleConn Med · March 2010
BACKGROUND: Surgery is gradually gaining recognition within the international public health community as an essential component to sustainable improvements in health care in resource-poor areas. In this article, we document the University of Connecticut ex ...
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Journal articleAnn Plast Surg · December 2008
Snowblowers injure approximately 5000 people a year and can cause devastating hand injuries. Even with added safety measures and warnings on modern snowblowers, hand injuries are still occurring at an alarming rate. We have reviewed our series of snowblowe ...
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Journal articleAppl Environ Microbiol · November 2001
A PCR approach was used to construct a database of nasA genes (called narB genes in cyanobacteria) and to detect the genetic potential for heterotrophic bacterial nitrate utilization in marine environments. A nasA-specific PCR primer set that could be used ...
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Journal articleJ Phycol · August 26, 2000
An approximately 16-kb fragment of the Trichodesmium sp. IMS101 (a nonheterocystous filamentous cyanobacterium) "conventional"nif gene cluster was cloned and sequenced. The gene organization of the Trichodesmium and Anabaena variabilis vegetative (nif 2) n ...
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Journal articlePlant Mol Biol · September 1999
The daily cycle of nitrogenase expression in the marine filamentous nonheterocystous cyanobacterium Trichodesmium spp. is controlled by a circadian rhythm. We evaluated the rhythm of two key photosynthesis genes, psbA of photosystem II and psaA of photosys ...
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Journal articleAppl Environ Microbiol · September 1998
Oligotrophic oceanic waters of the central ocean gyres typically have extremely low dissolved fixed inorganic nitrogen concentrations, but few nitrogen-fixing microorganisms from the oceanic environment have been cultivated. Nitrogenase gene (nifH) sequenc ...
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