Sallie Robey Permar | Scholars@Duke

Sallie Robey Permar
Professor of Pediatrics

Dr. Permar's work focuses on the development of vaccines to prevent vertical transmission of neonatal viral pathogens. She has utilized the nonhuman primate model of HIV/AIDS to characterize the virus-specific immune responses and virus evolution in breast milk and develop a maternal vaccine regimen for protection against breast milk transmission of HIV. In addition, Dr. Permar's lab has advanced the understanding of HIV-specific immune responses and virus evolution in vertically-transmitting and nontransmitting HIV-infected women, defining maternal immune responses that may protect against neonatal transmission of HIV. Importantly, Dr. Permar has established a nonhuman primate model of congenital CMV infection adn is using this model to establish the maternal immune responses that are necessary for protection against placental virus transmission. Finally, Dr. Permar is studying the impact and prevention of postnatal CMV transmission in preterm infants.

Current Appointments & Affiliations

Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2017
Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2017
Professor in Immunology, Immunology, Basic Science Departments 2017
Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2011
Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2013
Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2017
Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2018

Contact Information

103020, 2 Genome Ct MSRBII, Durham, NC 27710
Duke Human Vaccine Institute, Box 103020 MSRBII Rm 3072A, Durham, NC 27710
sallie.permar@duke.edu (919) 684-2515
DHVI - Neonatal Viral Pathogen Immunity Lab
Permar Lab Website

Background
Education, Training, & Certifications
- Fellowship in Pediatric Infectious Diseases, Pediatrics, Children's Hospital Boston 2007 - 2009
- Pediatric Residency, Pediatrics, Children's Hospital Boston 2004 - 2007
- M.D., Harvard Medical School 2004
- Ph.D., Johns Hopkins University 2004
Duke Appointment History
- Associate Professor in Immunology, Immunology, Basic Science Departments 2015 - 2017
- Associate Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2015 - 2017
- Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2015 - 2017
- Assistant Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2012 - 2015
- Assistant Professor in Immunology, Immunology, Basic Science Departments 2012 - 2015
- Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2013 - 2015
- Assistant Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2011 - 2013
Recognition
In the News
- JUL 7, 2017 Duke Health News
  
  Antibodies Halt Placental Transmission of CMV-Like Virus in Monkeys
- JUN 8, 2016 The News & Observer
  
  Zika research, prevention discussed at N.C. conference
- FEB 5, 2016 Smithsonian
  
  Dr. Sallie Permar: How can viruses like Zika cause birth defects?
- FEB 2, 2016 WUNC
  
  Triangle researchers mobilize against threat of Zika virus
- JAN 28, 2016
  
  Sallie Permar on What is Unusual about the Zika Virus
- OCT 20, 2015
  
  Monkey model discovery could spur CMV vaccine development
- JUN 10, 2015
  
  Antibody Response Linked To Lower Mother-to-Child HIV Transmission
- APR 6, 2015 The News & Observer
  
  Duke HIV researchers receive large federal grants
- APR 21, 2014 The News & Observer
  
  Tar Heel of the Week: Scientist Sallie Permar intent on stopping childhood diseases
- JAN 5, 2014
  
  Duke Medical Researcher Sallie Permar Receives White House Honor
- DEC 30, 2013 News & Observer
  
  Two Triangle scientists honored by White House
Awards & Honors
Expertise
Global Scholarship
- Research
  - Malawi (Country)
  - South Africa (Country)
Research
Selected Grants
- Nasopharyngeal Microbiome and Risk of Bacterial Pathogen Colonization in Infants awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Duke Resident Physician-Scientist Program- NIAID awarded by National Institutes of Health 2018 - 2022
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- The origin, predictors, and immune correlates of viral rebound in orally SHIV infected infant monkeys awarded by National Institutes of Health 2017 - 2022
- Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
- Research Training in Allergy and Clinical Immunology awarded by National Institutes of Health 2000 - 2021
- Clinical and viral characteristics of maternal cytomegalovirus infection among seropositive pregnant women in the United States awarded by National Institutes of Health 2018 - 2020
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- Innate antiviral factors in breast milk and the oral HIV-1 reservoir awarded by National Institutes of Health 2015 - 2020
- The relationship between maternal ZIKV-specific and ADE antibodies and fetal outcome awarded by National Institutes of Health 2018 - 2020
- Role of neutralizing antibodies in HIV-1-infected and vaccinated mothers in MTCT awarded by National Institutes of Health 2016 - 2020
- Recombinant vectored delivery of maternal antibody for transfer into breast milk and across the placenta awarded by Bill and Melinda Gates Foundation 2018 - 2020
- Maternal and infant immunization to eliminate breast milk transmission of HIV-1 awarded by National Institutes of Health 2015 - 2020
- Antibody and viral determinants of protection against CMV infection following gB/MF59 vaccination awarded by National Institutes of Health 2017 - 2020
- Antibody and viral determinants of protection against CMV infection following gB/MF59 vaccination awarded by National Institutes of Health 2018 - 2019
- Immune responses during primary CMV infection in pregnancy that correlate with viral containment awarded by Thrasher Research Fund 2018 - 2019
- Development of broadly neutralizing antibody responses in HIV-infected children awarded by Doris Duke Charitable Foundation 2018 - 2019
- Identifying key determinants of IgG transplacental transfer from HIV-infected mothers to their fetus awarded by Burroughs Wellcome Fund 2017 - 2019
- Zika virus pathophysiology during pregnancy awarded by University of Wisconsin - Madison 2018 - 2019
- Assessment of diverse anti-HCMV antibody functions elicited by mRNA vaccines expressing the gB and pentameric complex awarded by Moderna Therapeutics, Inc. 2018 - 2019
- Characterization of the immune response to primary CMV infection during pregnancy in a nonhuman primate model and in women enrolled in the MFMU CMV trial (NCT01376778) awarded by Pediatric Infectious Diseases Society 2017 - 2019
- Rapid, Near Patient Nucleic Acid Testing for Infant Cytomegalovirus (CMV) Infection awarded by Baebies, Inc 2017 - 2019
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2019
- Transmission-blocking potential of novel HIV Env-specific mucosal antibodies awarded by National Institutes of Health 2013 - 2019
- Statistical methods for HIV-1 immune correlates studies awarded by Fred Hutchinson Cancer Research Center 2016 - 2019
- Screening CMV-specific rhesus mab for neutralizing function awarded by Merck Sharp & Dohme 2017 - 2019
- Isolation of protective ZIKV-neutralizing maternal monoclonal antibodies for safe prophylactic use in the preconception period awarded by American Society for Reproductive Medicine 2017 - 2019
- Pregnant rabbits as a model to evaluate the causative role of ZIKV infection in the etiology of congenital malformations awarded by National Institutes of Health 2017 - 2018
- International Maternal Pediatric Adolescent AIDS Clinical Trial (IMPAACT) Group awarded by University of California - Los Angeles 2016 - 2018
- Identifying key determinants of IgG transplacental transfer from HIV-infected mothers to their fetus awarded by National Institutes of Health 2017 - 2018
- Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
- Hyperimmune globulin treatment of Zika virus during pregnancy to reduce Congenital Zika Syndrome awarded by University of Wisconsin - Madison 2017 - 2018
- The B cell repertoire and antibody maturation elicited by adjuvanted HIV envelope vaccines in infants awarded by Doris Duke Charitable Foundation 2016 - 2018
- LOC-IMPAACT Leadership Group awarded by Johns Hopkins University 2014 - 2017
- Development of a nonhuman primate model of fetal Zika virus infection and disease awarded by University of California - Davis 2017
- Maternal immune protection against congenital CMV infection awarded by National Institutes of Health 2012 - 2017
- Mucosal vaccination to protect against HIV-1 infection at mucosal sites awarded by National Institutes of Health 2012 - 2017
- Identifying maternal immune correlates of protection against perinatal mother-to-child transmission (MTCT) awarded by Doris Duke Charitable Foundation 2015 - 2017
- Infant immune correlates of perinatal mother to child transmission of HIV awarded by National Institutes of Health 2015 - 2017
- Permar IMPAACT 2004 stability study QAU awarded by Johns Hopkins University 2014 - 2016
- Simple interventions to Improve Rotavirus Vaccine Effectiveness (SIRVE) awarded by University of North Carolina - Chapel Hill 2014 - 2016
- Gut Bacteria Prime B cells towards gp120-specific response in African Green Monkeys. awarded by Sigma Xi 2015 - 2016
- Statistical methods for HIV-1 immune correlates studies awarded by Fred Hutchinson Cancer Research Center 2015 - 2016
- Vaccine-induced HIV antibody responses in infants awarded by National Institutes of Health 2012 - 2015
- SIV-specific immunity in breast milk during infection and after vaccination awarded by National Institutes of Health 2009 - 2014
- Antibody protection against SIV transmission awarded by National Institutes of Health 2012 - 2014
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Dennis, M, Eudailey, J, Pollara, J, McMillan, AS, Cronin, KD, Saha, PT, Curtis, AD, Hudgens, MG, Fouda, GG, Ferrari, G, Alam, M, Van Rompay, KKA, De Paris, K, Permar, S, and Shen, X. "Co-administration of CH31 broadly neutralizing antibody does not affect development of vaccine-induced anti-HIV-1 envelope antibody responses in infant Rhesus macaques." Journal of Virology (December 12, 2018). Full Text
  - Nelson, CS, Cruz, DV, Su, M, Xie, G, Vandergrift, N, Pass, RF, Forman, M, Diener-West, M, Koelle, K, Arav-Boger, R, and Permar, SR. "Intrahost dynamics of human cytomegalovirus variants acquired by seronegative glycoprotein B vaccinees." Journal of Virology (December 5, 2018). Full Text
  - Shah, SV, Manickam, C, Ram, DR, Kroll, K, Itell, H, Permar, SR, Barouch, DH, Klatt, NR, and Reeves, RK. "CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques." Cell Reports 25, no. 10 (December 2018): 2766-2774.e3. Full Text
  - Himes, JE, Goswami, R, Mangan, RJ, Kumar, A, Jeffries, TL, Eudailey, JA, Heimsath, H, Nguyen, QN, Pollara, J, LaBranche, C, Chen, M, Vandergrift, NA, Peacock, JW, Schiro, F, Midkiff, C, Ferrari, G, Montefiori, DC, Hernandez, XA, Aye, PP, and Permar, SR. "Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys." Mucosal Immunology 11, no. 6 (November 2018): 1716-1726. Full Text
  - Lantos, PM, Maradiaga-Panayotti, G, Barber, X, Raynor, E, Tucci, D, Hoffman, K, Permar, SR, Jackson, P, Hughes, BL, Kind, A, and Swamy, GK. "Geographic and Racial Disparities in Infant Hearing Loss." Otolaryngology Head and Neck Surgery : Official Journal of American Academy of Otolaryngology Head and Neck Surgery (October 9, 2018): 194599818803305-null. Full Text Open Access Copy
  - Permar, S, Levy, O, Kollman, TR, Singh, A, and De Paris, K. "Early Life HIV-1 Immunization: Providing a Window for Protection Before Sexual Debut." Aids Research and Human Retroviruses 34, no. 10 (October 2018): 823-827. Full Text
  - Phillips, B, Van Rompay, KKA, Rodriguez-Nieves, J, Lorin, C, Koutsoukos, M, Tomai, M, Fox, CB, Eudailey, J, Dennis, M, Alam, SM, Hudgens, M, Fouda, G, Pollara, J, Moody, A, Shen, X, Ferrari, G, Permar, S, and De Paris, K. "Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques." Journal of Virology 92, no. 20 (October 2018). Full Text
  - Itell, HL, McGuire, EP, Muresan, P, Cunningham, CK, McFarland, EJ, Borkowsky, W, Permar, SR, and Fouda, GG. "Development and application of a multiplex assay for the simultaneous measurement of antibody responses elicited by common childhood vaccines." Vaccine 36, no. 37 (September 2018): 5600-5608. Full Text
  - Martinez, DR, Fouda, GG, Peng, X, Ackerman, ME, and Permar, SR. "Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?." Plos Pathogens 14, no. 8 (August 30, 2018): e1007161-null. Full Text
  - Burghuber, CK, Manook, M, Ezekian, B, Gibby, AC, Leopardi, FV, Song, M, Jenks, J, Saccoccio, F, Permar, S, Farris, AB, Iwakoshi, NN, Kwun, J, and Knechtle, SJ. "Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons (August 13, 2018). Full Text
  - Lantos, PM, Hoffman, K, Permar, SR, Jackson, P, Hughes, BL, Kind, A, and Swamy, G. "Neighborhood Disadvantage is Associated with High Cytomegalovirus Seroprevalence in Pregnancy." Journal of Racial and Ethnic Health Disparities 5, no. 4 (August 2018): 782-786. Full Text Open Access Copy
  - Permar, SR, Schleiss, MR, and Plotkin, SA. "Reply to Gantt et al., "Higher Expectations for a Vaccine To Prevent Congenital Cytomegalovirus Infection"." Journal of Virology 92, no. 15 (August 2018). Full Text
  - Coffey, LL, Keesler, RI, Pesavento, PA, Woolard, K, Singapuri, A, Watanabe, J, Cruzen, C, Christe, KL, Usachenko, J, Yee, J, Heng, VA, Bliss-Moreau, E, Reader, JR, von Morgenland, W, Gibbons, AM, Jackson, K, Ardeshir, A, Heimsath, H, Permar, S, Senthamaraikannan, P, Presicce, P, Kallapur, SG, Linnen, JM, Gao, K, Orr, R, MacGill, T, McClure, M, McFarland, R, Morrison, JH, and Van Rompay, KKA. "Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease." Nature Communications 9, no. 1 (June 20, 2018): 2414-null. Full Text
  - Nelson, CS, Huffman, T, Jenks, JA, Cisneros de la Rosa, E, Xie, G, Vandergrift, N, Pass, RF, Pollara, J, and Permar, SR. "HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions." Proceedings of the National Academy of Sciences of the United States of America 115, no. 24 (June 2018): 6267-6272. Full Text
  - Ram, DR, Manickam, C, Hueber, B, Itell, HL, Permar, SR, Varner, V, and Reeves, RK. "Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques." Plos Pathogens 14, no. 5 (May 31, 2018): e1007104-null. Full Text
  - Jegaskanda, S, Mason, RD, Andrews, SF, Wheatley, AK, Zhang, R, Reynoso, GV, Ambrozak, DR, Santos, CP, Luke, CJ, Matsuoka, Y, Brenchley, JM, Hickman, HD, Talaat, KR, Permar, SR, Liao, H-X, Yewdell, JW, Koup, RA, Roederer, M, McDermott, AB, and Subbarao, K. "Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes." Journal of Virology 92, no. 9 (May 2018). Full Text
  - Kumar, A, Smith, CEP, Giorgi, EE, Eudailey, J, Martinez, DR, Yusim, K, Douglas, AO, Stamper, L, McGuire, E, LaBranche, CC, Montefiori, DC, Fouda, GG, Gao, F, and Permar, SR. "Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma." Plos Pathogens 14, no. 4 (April 19, 2018): e1006944-null. Full Text
  - Permar, SR, Schleiss, MR, and Plotkin, SA. "Advancing Our Understanding of Protective Maternal Immunity as a Guide for Development of Vaccines To Reduce Congenital Cytomegalovirus Infections." Journal of Virology 92, no. 7 (April 2018). (Review) Full Text
  - Nguyen, QN, Martinez, DR, Himes, JE, Whitney Edwards, R, Han, Q, Kumar, A, Mangan, R, Nicely, NI, Xie, G, Vandergrift, N, Shen, X, Pollara, J, and Permar, SR. "Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys." Retrovirology 15, no. 1 (March 9, 2018): 24-null. Full Text
  - Premkumar, L, Collins, M, Graham, S, Liou, G-JA, Lopez, CA, Jadi, R, Balmaseda, A, Brackbill, JA, Dietze, R, Camacho, E, De Silva, AD, Giuberti, C, Dos Reis, HL, Singh, T, Heimsath, H, Weiskopf, D, Sette, A, Osorio, JE, Permar, SR, Miley, MJ, Lazear, HM, Harris, E, and de Silva, AM. "Development of Envelope Protein Antigens To Serologically Differentiate Zika Virus Infection from Dengue Virus Infection." Journal of Clinical Microbiology 56, no. 3 (March 2018). Full Text
  - Eudailey, JA, Dennis, ML, Parker, ME, Phillips, BL, Huffman, TN, Bay, CP, Hudgens, MG, Wiseman, RW, Pollara, JJ, Fouda, GG, Ferrari, G, Pickup, DJ, Kozlowski, PA, Van Rompay, KKA, De Paris, K, and Permar, SR. "Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques." Msphere 3, no. 1 (January 10, 2018). Full Text Open Access Copy
  - Fouda, GG, Martinez, DR, Swamy, GK, and Permar, SR. "The Impact of IgG transplacental transfer on early life immunity." Immunohorizons 2, no. 1 (January 2018): 14-25. Full Text
  - Kaur, A, Itell, HL, Ehlinger, EP, Varner, V, Gantt, S, and Permar, SR. "Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys." Plos One 13, no. 10 (January 2018): e0206330-null. Full Text
  - McGuire, EP, Fong, Y, Toote, C, Cunningham, CK, McFarland, EJ, Borkowsky, W, Barnett, S, Itell, HL, Kumar, A, Gray, G, McElrath, MJ, Tomaras, GD, Permar, SR, and Fouda, GG. "HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine." Journal of Virology 92, no. 1 (January 2018). Full Text
  - Nelson, CS, Herold, BC, and Permar, SR. "A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection." Npj Vaccines 3 (January 2018): 38-null. (Review) Full Text
  - Schleiss, MR, Permar, SR, and Plotkin, SA. "Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection." Clinical and Vaccine Immunology : Cvi 24, no. 12 (December 5, 2017). (Review) Full Text
  - Itell, HL, Nelson, CS, Martinez, DR, and Permar, SR. "Maternal immune correlates of protection against placental transmission of cytomegalovirus." Placenta 60 Suppl 1 (December 2017): S73-S79. (Review) Full Text
  - Voronin, Y, Jani, I, Graham, BS, Cunningham, CK, Mofenson, LM, Musoke, PM, Permar, SR, and Scarlatti, G. "Recent progress in immune-based interventions to prevent HIV-1 transmission to children." Journal of the International Aids Society 20, no. 4 (December 2017). Full Text
  - Han, Q, Williams, WB, Saunders, KO, Seaton, KE, Wiehe, KJ, Vandergrift, N, Von Holle, TA, Trama, AM, Parks, RJ, Luo, K, Gurley, TC, Kepler, TB, Marshall, DJ, Montefiori, DC, Sutherland, LL, Alam, MS, Whitesides, JF, Bowman, CM, Permar, SR, Graham, BS, Mascola, JR, Seed, PC, Van Rompay, KKA, Tomaras, GD, Moody, MA, and Haynes, BF. "HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques." Journal of Virology 91, no. 21 (November 2017). Full Text
  - Fong, Y, Huang, Y, Gilbert, PB, and Permar, SR. "chngpt: threshold regression model estimation and inference." Bmc Bioinformatics 18, no. 1 (October 16, 2017): 454-null. Full Text
  - Lantos, PM, Hoffman, K, Permar, SR, Jackson, P, Hughes, BL, and Swamy, GK. "Geographic Disparities in Cytomegalovirus Infection During Pregnancy." Journal of the Pediatric Infectious Diseases Society 6, no. 3 (September 2017): e55-e61. Full Text
  - Mutucumarana, CP, Eudailey, J, McGuire, EP, Vandergrift, N, Tegha, G, Chasela, C, Ellington, S, van der Horst, C, Kourtis, AP, Permar, SR, and Fouda, GG. "Maternal Humoral Immune Correlates of Peripartum Transmission of Clade C HIV-1 in the Setting of Peripartum Antiretrovirals." Clinical and Vaccine Immunology : Cvi 24, no. 8 (August 4, 2017). Full Text
  - Itell, HL, Kaur, A, Deere, JD, Barry, PA, and Permar, SR. "Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections." Current Opinion in Virology 25 (August 2017): 126-133. (Review) Full Text
  - Nelson, CS, Cruz, DV, Tran, D, Bialas, KM, Stamper, L, Wu, H, Gilbert, M, Blair, R, Alvarez, X, Itell, H, Chen, M, Deshpande, A, Chiuppesi, F, Wussow, F, Diamond, DJ, Vandergrift, N, Walter, MR, Barry, PA, Cohen-Wolkowiez, M, Koelle, K, Kaur, A, and Permar, SR. "Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys." JCI insight 2, no. 13 (July 6, 2017). Full Text
  - Nguyen, SM, Antony, KM, Dudley, DM, Kohn, S, Simmons, HA, Wolfe, B, Salamat, MS, Teixeira, LBC, Wiepz, GJ, Thoong, TH, Aliota, MT, Weiler, AM, Barry, GL, Weisgrau, KL, Vosler, LJ, Mohns, MS, Breitbach, ME, Stewart, LM, Rasheed, MN, Newman, CM, Graham, ME, Wieben, OE, Turski, PA, Johnson, KM, Post, J, Hayes, JM, Schultz-Darken, N, Schotzko, ML, Eudailey, JA, Permar, SR, Rakasz, EG, Mohr, EL, Capuano, S, Tarantal, AF, Osorio, JE, O'Connor, SL, Friedrich, TC, O'Connor, DH, and Golos, TG. "Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques." Plos Pathogens 13, no. 5 (May 25, 2017): e1006378-null. Full Text
  - Fan, Q, Nelson, CS, Bialas, KM, Chiuppesi, F, Amos, J, Gurley, TC, Marshall, DJ, Eudailey, J, Heimsath, H, Himes, J, Deshpande, A, Walter, MR, Wussow, F, Diamond, DJ, Barry, PA, Moody, MA, Kaur, A, and Permar, SR. "Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission." Clinical and vaccine immunology : CVI 24, no. 5 (May 2017). Full Text
  - Martinez, DR, Vandergrift, N, Douglas, AO, McGuire, E, Bainbridge, J, Nicely, NI, Montefiori, DC, Tomaras, GD, Fouda, GG, and Permar, SR. "Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk." Journal of virology 91, no. 9 (May 2017). Full Text
  - Becker-Dreps, S, Choi, WS, Stamper, L, Vilchez, S, Velasquez, DE, Moon, S-S, Hudgens, MG, Jiang, B, and Permar, SR. "Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants." Journal of the Pediatric Infectious Diseases Society 6, no. 1 (March 2017): 87-90. Full Text
  - Mwila, K, Chilengi, R, Simuyandi, M, Permar, SR, and Becker-Dreps, S. "Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries." Clinical and Vaccine Immunology : Cvi 24, no. 1 (January 5, 2017). (Review) Full Text
  - Douglas, AO, Martinez, DR, and Permar, SR. "The Role of Maternal HIV Envelope-Specific Antibodies and Mother-to-Child Transmission Risk." Frontiers in immunology 8 (January 2017): 1091-. (Review) Full Text
  - Fouda, GG, Eudailey, J, Kunz, EL, Amos, JD, Liebl, BE, Himes, J, Boakye-Agyeman, F, Beck, K, Michaels, AJ, Cohen-Wolkowiez, M, Haynes, BF, Reimann, KA, and Permar, SR. "Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization." Mucosal immunology 10, no. 1 (January 2017): 228-237. Full Text
  - Mwila-Kazimbaya, K, Garcia, MP, Bosomprah, S, Laban, NM, Chisenga, CC, Permar, SR, Simuyandi, M, Munsaka, S, and Chilengi, R. "Effect of innate antiviral glycoproteins in breast milk on seroconversion to rotavirus vaccine (Rotarix) in children in Lusaka, Zambia." Plos One 12, no. 12 (January 2017): e0189351-null. Full Text
  - Nguyen, QN, Himes, JE, Martinez, DR, and Permar, SR. "The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy." Plos Pathogens 12, no. 12 (December 22, 2016): e1005997-null. (Review) Full Text
  - Aliota, MT, Dudley, DM, Newman, CM, Mohr, EL, Gellerup, DD, Breitbach, ME, Buechler, CR, Rasheed, MN, Mohns, MS, Weiler, AM, Barry, GL, Weisgrau, KL, Eudailey, JA, Rakasz, EG, Vosler, LJ, Post, J, Capuano, S, Golos, TG, Permar, SR, Osorio, JE, Friedrich, TC, O'Connor, SL, and O'Connor, DH. "Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques." Plos Neglected Tropical Diseases 10, no. 12 (December 2, 2016): e0005168-null. Full Text
  - Bialas, KM, Westreich, D, Cisneros de la Rosa, E, Nelson, CS, Kauvar, LM, Fu, T-M, and Permar, SR. "Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants." The Journal of infectious diseases 214, no. 12 (December 2016): 1916-1923. Full Text
  - Himes, JE, Ho, C, Nguyen, QN, Amos, JD, Xu, H, Chan, C, Chow, S-C, Ochsenbauer, C, Kaidarova, Z, Keating, SM, Fouda, GG, and Permar, SR. "Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys." Journal of Virology 90, no. 19 (October 2016): 8795-8808. Full Text
  - Zhang, R, Alam, SM, Yu, J-S, Scearce, R, Lockwood, B, Hwang, K-K, Parks, R, Permar, S, Brandtzaeg, P, Haynes, BF, and Liao, H-X. "Novel Monoclonal Antibodies for Studies of Human and Rhesus Macaque Secretory Component and Human J-Chain." Monoclonal antibodies in immunodiagnosis and immunotherapy 35, no. 4 (August 2016): 217-226. Full Text
  - Zhang, R, Martinez, DR, Nguyen, QN, Pollara, J, Arifin, T, Stolarchuk, C, Foulger, A, Amos, JD, Parks, R, Himes, JE, Wang, M, Edwards, RW, Trama, AM, Vandergrift, N, Colvin, L, Dewar, K, Juretic, N, Wasserscheid, J, Ferrari, G, Liao, H-X, and Permar, SR. "Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus." Nature Communications 7 (July 6, 2016): 12131-null. Full Text
  - Mukhopadhyay, S, Meyer, SA, Permar, SR, and Puopolo, KM. "Symptomatic Postnatal Cytomegalovirus Testing among Very Low-Birth-Weight Infants: Indications and Outcomes." American journal of perinatology 33, no. 9 (July 2016): 894-902. Full Text
  - Dudley, DM, Aliota, MT, Mohr, EL, Weiler, AM, Lehrer-Brey, G, Weisgrau, KL, Mohns, MS, Breitbach, ME, Rasheed, MN, Newman, CM, Gellerup, DD, Moncla, LH, Post, J, Schultz-Darken, N, Schotzko, ML, Hayes, JM, Eudailey, JA, Moody, MA, Permar, SR, O'Connor, SL, Rakasz, EG, Simmons, HA, Capuano, S, Golos, TG, Osorio, JE, Friedrich, TC, and O'Connor, DH. "A rhesus macaque model of Asian-lineage Zika virus infection." Nature Communications 7 (June 28, 2016): 12204-null. Full Text
  - Nelson, CS, Pollara, J, Kunz, EL, Jeffries, TL, Duffy, R, Beck, C, Stamper, L, Wang, M, Shen, X, Pickup, DJ, Staats, HF, Hudgens, MG, Kepler, TB, Montefiori, DC, Moody, MA, Tomaras, GD, Liao, H-X, Haynes, BF, Ferrari, G, Fouda, GGA, and Permar, SR. "Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk." Journal of Virology 90, no. 10 (May 2016): 4951-4965. Full Text
  - Jeffries, TL, Sacha, CR, Pollara, J, Himes, J, Jaeger, FH, Dennison, SM, McGuire, E, Kunz, E, Eudailey, JA, Trama, AM, LaBranche, C, Fouda, GG, Wiehe, K, Montefiori, DC, Haynes, BF, Liao, H-X, Ferrari, G, Alam, SM, Moody, MA, and Permar, SR. "The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells." Mucosal Immunology 9, no. 2 (March 2016): 414-427. Full Text
  - Bialas, KM, and Permar, SR. "The March towards a Vaccine for Congenital CMV: Rationale and Models." Plos Pathogens 12, no. 2 (February 11, 2016): e1005355-null. Full Text
  - Martinez, DR, Permar, SR, and Fouda, GG. "Contrasting Adult and Infant Immune Responses to HIV Infection and Vaccination." Clinical and Vaccine Immunology : Cvi 23, no. 2 (February 2016): 84-94. (Review) Full Text
  - Mansour, RG, Stamper, L, Jaeger, F, McGuire, E, Fouda, G, Amos, J, Barbas, K, Ohashi, T, Alam, SM, Erickson, H, and Permar, SR. "The Presence and Anti-HIV-1 Function of Tenascin C in Breast Milk and Genital Fluids." Plos One 11, no. 5 (January 2016): e0155261-null. Full Text
  - Kelly, MS, Benjamin, DK, Puopolo, KM, Laughon, MM, Clark, RH, Mukhopadhyay, S, Benjamin, DK, Smith, PB, and Permar, SR. "Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia." JAMA pediatrics 169, no. 12 (December 7, 2015): e153785-. Full Text
  - Lantos, PM, Permar, SR, Hoffman, K, and Swamy, GK. "The Excess Burden of Cytomegalovirus in African American Communities: A Geospatial Analysis." Open Forum Infectious Diseases 2, no. 4 (December 2015): ofv180-null. Full Text Open Access Copy
  - Bialas, KM, Tanaka, T, Tran, D, Varner, V, Cisneros De La Rosa, E, Chiuppesi, F, Wussow, F, Kattenhorn, L, Macri, S, Kunz, EL, Estroff, JA, Kirchherr, J, Yue, Y, Fan, Q, Lauck, M, O'Connor, DH, Hall, AHS, Xavier, A, Diamond, DJ, Barry, PA, Kaur, A, and Permar, SR. "Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission." Proceedings of the National Academy of Sciences of the United States of America 112, no. 44 (November 2015): 13645-13650. Full Text
  - Wahl, A, Baker, C, Spagnuolo, RA, Stamper, LW, Fouda, GG, Permar, SR, Hinde, K, Kuhn, L, Bode, L, Aldrovandi, GM, and Garcia, JV. "Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity." Journal of Virology 89, no. 21 (November 2015): 10868-10878. Full Text
  - Pollara, J, McGuire, E, Fouda, GG, Rountree, W, Eudailey, J, Overman, RG, Seaton, KE, Deal, A, Edwards, RW, Tegha, G, Kamwendo, D, Kumwenda, J, Nelson, JAE, Liao, H-X, Brinkley, C, Denny, TN, Ochsenbauer, C, Ellington, S, King, CC, Jamieson, DJ, van der Horst, C, Kourtis, AP, Tomaras, GD, Ferrari, G, and Permar, SR. "Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1." Journal of Virology 89, no. 19 (October 2015): 9952-9961. Full Text Open Access Copy
  - Amos, JD, Himes, JE, Armand, L, Gurley, TC, Martinez, DR, Colvin, L, Beck, K, Overman, RG, Liao, H-X, Moody, MA, and Permar, SR. "Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys." Journal of Virology 89, no. 18 (September 2015): 9485-9498. Full Text
  - Shen, X, Duffy, R, Howington, R, Cope, A, Sadagopal, S, Park, H, Pal, R, Kwa, S, Ding, S, Yang, OO, Fouda, GG, Le Grand, R, Bolton, D, Esteban, M, Phogat, S, Roederer, M, Amara, RR, Picker, LJ, Seder, RA, McElrath, MJ, Barnett, S, Permar, SR, Shattock, R, DeVico, AL, Felber, BK, Pavlakis, GN, Pantaleo, G, Korber, BT, Montefiori, DC, and Tomaras, GD. "Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates." Journal of Virology 89, no. 16 (August 2015): 8643-8650. Full Text
  - Permar, SR, Fong, Y, Vandergrift, N, Fouda, GG, Gilbert, P, Parks, R, Jaeger, FH, Pollara, J, Martelli, A, Liebl, BE, Lloyd, K, Yates, NL, Overman, RG, Shen, X, Whitaker, K, Chen, H, Pritchett, J, Solomon, E, Friberg, E, Marshall, DJ, Whitesides, JF, Gurley, TC, Von Holle, T, Martinez, DR, Cai, F, Kumar, A, Xia, S-M, Lu, X, Louzao, R, Wilkes, S, Datta, S, Sarzotti-Kelsoe, M, Liao, H-X, Ferrari, G, Alam, SM, Montefiori, DC, Denny, TN, Moody, MA, Tomaras, GD, Gao, F, and Haynes, BF. "Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission." The Journal of Clinical Investigation 125, no. 7 (July 2015): 2702-2706. Full Text Open Access Copy
  - Richard, J, Veillette, M, Brassard, N, Iyer, SS, Roger, M, Martin, L, Pazgier, M, Schön, A, Freire, E, Routy, J-P, Smith, AB, Park, J, Jones, DM, Courter, JR, Melillo, BN, Kaufmann, DE, Hahn, BH, Permar, SR, Haynes, BF, Madani, N, Sodroski, JG, and Finzi, A. "CD4 mimetics sensitize HIV-1-infected cells to ADCC." Proceedings of the National Academy of Sciences of the United States of America 112, no. 20 (May 4, 2015): E2687-E2694. Full Text
  - Fouda, GG, Moody, MA, and Permar, SR. "Antibodies for prevention of mother-to-child transmission of HIV-1." Current Opinion in Hiv and Aids 10, no. 3 (May 2015): 177-182. (Review) Full Text
  - Fong, Y, Di, C, and Permar, S. "Change point testing in logistic regression models with interaction term." Statistics in medicine 34, no. 9 (April 2015): 1483-1494. Full Text
  - Fouda, GG, Cunningham, CK, and Permar, SR. "Infant HIV-1 vaccines: supplementing strategies to reduce maternal-child transmission." Jama 313, no. 15 (April 2015): 1513-1514. Full Text
  - Wright, CJ, and Permar, SR. "Preventing postnatal cytomegalovirus infection in the preterm infant: should it be done, can it be done, and at what cost?." The Journal of pediatrics 166, no. 4 (April 2015): 795-798. Full Text
  - Bialas, KM, Swamy, GK, and Permar, SR. "Perinatal cytomegalovirus and varicella zoster virus infections: epidemiology, prevention, and treatment." Clinics in Perinatology 42, no. 1 (March 2015): 61-viii. (Review) Full Text
  - Sacha, CR, Vandergrift, N, Jeffries, TL, McGuire, E, Fouda, GG, Liebl, B, Marshall, DJ, Gurley, TC, Stiegel, L, Whitesides, JF, Friedman, J, Badiabo, A, Foulger, A, Yates, NL, Tomaras, GD, Kepler, TB, Liao, HX, Haynes, BF, Moody, MA, and Permar, SR. "Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women." Mucosal Immunology 8, no. 2 (March 2015): 316-326. Full Text
  - Fouda, GG, Cunningham, CK, McFarland, EJ, Borkowsky, W, Muresan, P, Pollara, J, Song, LY, Liebl, BE, Whitaker, K, Shen, X, Vandergrift, NA, Overman, RG, Yates, NL, Moody, MA, Fry, C, Kim, JH, Michael, NL, Robb, M, Pitisuttithum, P, Kaewkungwal, J, Nitayaphan, S, Rerks-Ngarm, S, Liao, H-X, Haynes, BF, Montefiori, DC, Ferrari, G, Tomaras, GD, and Permar, SR. "Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses." The Journal of Infectious Diseases 211, no. 4 (February 2015): 508-517. Full Text
  - Bialas, KM, Swamy, GK, and Permar, SR. "Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment." Neoreviews 16, no. 4 (January 1, 2015): e231-e235. Full Text
  - Smith, SD, Amos, JD, Beck, KN, Colvin, LM, Franke, KS, Liebl, BE, and Permar, SR. "Refinement of a protocol for the induction of lactation in nonpregnant nonhuman primates by using exogenous hormone treatment." Journal of the American Association for Laboratory Animal Science : JAALAS 53, no. 6 (November 2014): 700-707.
  - Chahroudi, A, Cartwright, E, Carnathan, DG, Lee, ST, Lawson, B, Carnathan, PM, Hashempoor, T, Murphy, MK, Meeker, T, Ehnert, S, Souder, C, Else, JG, Cohen, J, Vanderford, TH, Permar, SR, Derdeyn, CA, Villinger, F, and Silvestri, G. "TARGET CELL AVAILABILITY, RATHER THAN BREAST MILK SPECIFIC FACTORS, DICTATES MOTHER-TO-INFANT TRANSMISSION OF SIV." JOURNAL OF MEDICAL PRIMATOLOGY 43, no. 5 (October 2014): 385-385. Link to Item
  - Kaur, A, Barry, P, Bialas, K, Tran, D, Varner, V, Kunz, E, Amos, J, Kirchherr, J, Kattenhorn, L, Wachtman, L, Tanaka, T, and Permar, SR. "SUCCESSFUL DEVELOPMENT OF A NONHUMAN PRIMATE MODEL OF CONGENITAL CYTOMEGALOVIRUS TRANSMISSION." JOURNAL OF MEDICAL PRIMATOLOGY 43, no. 5 (October 2014): 426-426. Link to Item
  - Dennison, SM, Anasti, KM, Jaeger, FH, Stewart, SM, Pollara, J, Liu, P, Kunz, EL, Zhang, R, Vandergrift, N, Permar, S, Ferrari, G, Tomaras, GD, Bonsignori, M, Michael, NL, Kim, JH, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Liao, H-X, Haynes, BF, and Alam, SM. "Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide." Journal of Virology 88, no. 16 (August 2014): 9406-9417. Full Text
  - Fouda, GG, and Permar, SR. "Immune-based interventions to prevent postnatal HIV-1 transmission." Trends in microbiology 22, no. 8 (August 2014): 425-427. Full Text
  - Chahroudi, A, Permar, S, and Pandrea, I. "SIV Transmission in Natural Hosts." (July 10, 2014): 257-268. (Chapter) Full Text
  - Madani, N, Princiotto, AM, Schön, A, LaLonde, J, Feng, Y, Freire, E, Park, J, Courter, JR, Jones, DM, Robinson, J, Liao, H-X, Moody, MA, Permar, S, Haynes, B, Smith, AB, Wyatt, R, and Sodroski, J. "CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies." Journal of Virology 88, no. 12 (June 2014): 6542-6555. Full Text
  - Permar, SR, and Staats, HF. "Which comes first: the antigen or the adjuvant?." The Journal of Clinical Investigation 124, no. 6 (June 2014): 2364-2365. Full Text
  - Chahroudi, A, Cartwright, E, Lee, ST, Mavigner, M, Carnathan, DG, Lawson, B, Carnathan, PM, Hashempoor, T, Murphy, MK, Meeker, T, Ehnert, S, Souder, C, Else, JG, Cohen, J, Collman, RG, Vanderford, TH, Permar, SR, Derdeyn, CA, Villinger, F, and Silvestri, G. "Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques." Plos Pathogens 10, no. 3 (March 6, 2014): e1003958-null. Full Text
  - Meyer, SA, Westreich, DJ, Patel, E, Ehlinger, EP, Kalilani, L, Lovingood, RV, Denny, TN, Swamy, GK, and Permar, SR. "Postnatal cytomegalovirus exposure in infants of antiretroviral-treated and untreated HIV-infected mothers." Infectious Diseases in Obstetrics and Gynecology 2014 (January 2014): 989721-null. Full Text Open Access Copy
  - Fouda, GG, Jaeger, FH, Amos, JD, Ho, C, Kunz, EL, Anasti, K, Stamper, LW, Liebl, BE, Barbas, KH, Ohashi, T, Moseley, MA, Liao, H-X, Erickson, HP, Alam, SM, and Permar, SR. "Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk." Proc Natl Acad Sci U S A 110, no. 45 (November 5, 2013): 18220-18225. Full Text Open Access Copy Link to Item
  - Amos, JD, Wilks, AB, Fouda, GG, Smith, SD, Colvin, L, Mahlokozera, T, Ho, C, Beck, K, Overman, RG, DeMarco, CT, Hodge, TL, LaBranche, CC, Montefiori, DC, Denny, TN, Liao, H-X, Tomaras, GD, Moody, MA, and Permar, SR. "Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys." Journal of Virology 87, no. 20 (October 2013): 11121-11134. Full Text Open Access Copy
  - Ho, C, Wu, S, Amos, JD, Colvin, L, Smith, SD, Wilks, AB, Demarco, CT, Brinkley, C, Denny, TN, Schmitz, JE, Rodrigo, AG, and Permar, SR. "Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys." Journal of Virology 87, no. 20 (October 2013): 11292-11299. Full Text Open Access Copy
  - Permar, SR, Salazar, MG, Gao, F, Cai, F, Learn, GH, Kalilani, L, Hahn, BH, Shaw, GM, and Salazar-Gonzalez, JF. "Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis." Retrovirology 10 (August 14, 2013): 88-null. Full Text
  - Fouda, GGA, Amos, JD, Wilks, AB, Pollara, J, Ray, CA, Chand, A, Kunz, EL, Liebl, BE, Whitaker, K, Carville, A, Smith, S, Colvin, L, Pickup, DJ, Staats, HF, Overman, G, Eutsey-Lloyd, K, Parks, R, Chen, H, Labranche, C, Barnett, S, Tomaras, GD, Ferrari, G, Montefiori, DC, Liao, H-X, Letvin, NL, Haynes, BF, and Permar, SR. "Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk." Journal of Virology 87, no. 12 (June 2013): 6986-6999. Full Text
  - Russell, ES, Ojeda, S, Fouda, GG, Meshnick, SR, Montefiori, D, Permar, SR, and Swanstrom, R. "Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes." Aids Research and Human Retroviruses 29, no. 3 (March 2013): 511-515. Full Text
  - Fouda, GG, Mahlokozera, T, Salazar-Gonzalez, JF, Salazar, MG, Learn, G, Kumar, SB, Dennison, SM, Russell, E, Rizzolo, K, Jaeger, F, Cai, F, Vandergrift, NA, Gao, F, Hahn, B, Shaw, GM, Ochsenbauer, C, Swanstrom, R, Meshnick, S, Mwapasa, V, Kalilani, L, Fiscus, S, Montefiori, D, Haynes, B, Kwiek, J, Alam, SM, and Permar, SR. "Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants.(Published online)" Retrovirology 10 (January 10, 2013): 3-null. Full Text Open Access Copy Link to Item
  - Handley, SA, Thackray, LB, Zhao, G, Presti, R, Miller, AD, Droit, L, Abbink, P, Maxfield, LF, Kambal, A, Duan, E, Stanley, K, Kramer, J, Macri, SC, Permar, SR, Schmitz, JE, Mansfield, K, Brenchley, JM, Veazey, RS, Stappenbeck, TS, Wang, D, Barouch, DH, and Virgin, HW. "Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome." Cell 151, no. 2 (October 2012): 253-266. Full Text
  - Schmitz, JE, Ma, Z-M, Hagan, EA, Wilks, AB, Furr, KL, Linde, CH, Zahn, RC, Brenchley, JM, Miller, CJ, and Permar, SR. "Memory CD4(+) T lymphocytes in the gastrointestinal tract are a major source of cell-associated simian immunodeficiency virus in chronic nonpathogenic infection of African green monkeys." Journal of Virology 86, no. 20 (October 2012): 11380-11385. Full Text
  - Fouda, G, Amos, J, Wilks, AB, Chand, A, Montefiori, D, Haynes, B, Letvin, N, Pickup, D, Liao, H, and Permar, SR. "Vaccine-elicited systemic and mucosal humoral responses of lactating rhesus monkeys vaccinated with the transmitted/founder HIV Envelope 1086C." Retrovirology 9, no. Suppl 2 (2012): O20-O20. Full Text
  - Friedman, J, Alam, SM, Shen, X, Xia, S-M, Stewart, S, Anasti, K, Pollara, J, Fouda, GG, Yang, G, Kelsoe, G, Ferrari, G, Tomaras, GD, Haynes, BF, Liao, H-X, Moody, MA, and Permar, SR. "Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum." Plos One 7, no. 5 (2012): e37648-null. Full Text Open Access Copy Link to Item
  - Parrish, NF, Wilen, CB, Banks, LB, Iyer, SS, Pfaff, JM, Salazar-Gonzalez, JF, Salazar, MG, Decker, JM, Parrish, EH, Berg, A, Hopper, J, Hora, B, Kumar, A, Mahlokozera, T, Yuan, S, Coleman, C, Vermeulen, M, Ding, H, Ochsenbauer, C, Tilton, JC, Permar, SR, Kappes, JC, Betts, MR, Busch, MP, Gao, F, Montefiori, D, Haynes, BF, Shaw, GM, Hahn, BH, and Doms, RW. "Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7." Plos Pathog 8, no. 5 (2012): e1002686-null. Full Text Link to Item
  - Ehlinger, EP, Webster, EM, Kang, HH, Cangialose, A, Simmons, AC, Barbas, KH, Burchett, SK, Gregory, ML, Puopolo, KM, and Permar, SR. "Maternal cytomegalovirus-specific immune responses and symptomatic postnatal cytomegalovirus transmission in very low-birth-weight preterm infants." J Infect Dis 204, no. 11 (December 1, 2011): 1672-1682. Full Text Link to Item
  - Fouda, GG, Yates, NL, Pollara, J, Shen, X, Overman, GR, Mahlokozera, T, Wilks, AB, Kang, HH, Salazar-Gonzalez, JF, Salazar, MG, Kalilani, L, Meshnick, SR, Hahn, BH, Shaw, GM, Lovingood, RV, Denny, TN, Haynes, B, Letvin, NL, Ferrari, G, Montefiori, DC, Tomaras, GD, Permar, SR, and Center for HIV/AIDS Vaccine Immunology, . "HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies." Journal of Virology 85, no. 18 (September 2011): 9555-9567. Full Text Open Access Copy
  - Wilks, AB, Perry, JR, Ehlinger, EP, Zahn, RC, White, R, Gauduin, M-C, Carville, A, Seaman, MS, Schmitz, JE, and Permar, SR. "High cell-free virus load and robust autologous humoral immune responses in breast milk of simian immunodeficiency virus-infected african green monkeys." Journal of Virology 85, no. 18 (September 2011): 9517-9526. Full Text
  - Sun, Y, Asmal, M, Lane, S, Permar, SR, Schmidt, SD, Mascola, JR, and Letvin, NL. "Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys." Journal of Virology 85, no. 14 (July 2011): 6906-6912. Full Text
  - Salazar-Gonzalez, JF, Salazar, MG, Learn, GH, Fouda, GG, Kang, HH, Mahlokozera, T, Wilks, AB, Lovingood, RV, Stacey, A, Kalilani, L, Meshnick, SR, Borrow, P, Montefiori, DC, Denny, TN, Letvin, NL, Shaw, GM, Hahn, BH, Permar, SR, and Center for HIV/AIDS Vaccine Immunology A0167854, . "Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing." Journal of Virology 85, no. 6 (March 2011): 2751-2763. Full Text Open Access Copy
  - Mahlokozera, T, Kang, HH, Goonetilleke, N, Stacey, AR, Lovingood, RV, Denny, TN, Kalilani, L, Bunn, JEG, Meshnick, SR, Borrow, P, Letvin, NL, Permar, SR, and Center for HIV/AIDS Vaccine Immunology, . "The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk." PLoS One 6, no. 8 (2011): e23735-. Full Text Open Access Copy Link to Item
  - Wilks, AB, Christian, EC, Seaman, MS, Sircar, P, Carville, A, Gomez, CE, Esteban, M, Pantaleo, G, Barouch, DH, Letvin, NL, and Permar, SR. "Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys." J Immunol 185, no. 11 (December 1, 2010): 7097-7106. Full Text Link to Item
  - Permar, SR, Wilks, AB, Ehlinger, EP, Kang, HH, Mahlokozera, T, Coffey, RT, Carville, A, Letvin, NL, and Seaman, MS. "Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys." Journal of Virology 84, no. 16 (August 2010): 8209-8218. Full Text
  - Permar, SR, Kang, HH, Wilks, AB, Mach, LV, Carville, A, Mansfield, KG, Learn, GH, Hahn, BH, and Letvin, NL. "Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys. (Published online)" Retrovirology 7 (February 1, 2010): 7-. Full Text Link to Item
  - Permar, SR, Kang, HH, Wilks, AB, Mach, LV, Carville, A, Mansfield, KG, Learn, GH, Hahn, BH, and Letvin, NL. "Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys." RETROVIROLOGY 7 (February 1, 2010). Full Text Link to Item
  - Permar, SR, Kang, HH, Carville, A, Wilks, AB, Mansfield, KG, Rao, SS, and Letvin, NL. "Preservation of memory CD4(+) T lymphocytes in breast milk of lactating rhesus monkeys during acute simian immunodeficiency virus infection." J Infect Dis 201, no. 2 (January 15, 2010): 302-310. Full Text Link to Item
  - Permar, SR, Kang, HH, Carville, A, Mansfield, KG, Gelman, RS, Rao, SS, Whitney, JB, and Letvin, NL. "Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys." J Immunol 181, no. 5 (September 1, 2008): 3643-3650. Link to Item
  - Permar, SR, Rao, SS, Sun, Y, Bao, S, Buzby, AP, Kang, HH, and Letvin, NL. "Clinical measles after measles virus challenge in simian immunodeficiency virus-infected measles virus-vaccinated rhesus monkeys." The Journal of Infectious Diseases 196, no. 12 (December 2007): 1784-1793. Full Text
  - Sun, Y, Permar, SR, Buzby, AP, and Letvin, NL. "Memory CD4+ T-lymphocyte loss and dysfunction during primary simian immunodeficiency virus infection." Journal of Virology 81, no. 15 (August 2007): 8009-8015. Full Text
  - Permar, SR, Griffin, DE, and Letvin, NL. "Immune containment and consequences of measles virus infection in healthy and immunocompromised individuals." Clinical and Vaccine Immunology : Cvi 13, no. 4 (April 2006): 437-443. (Review) Full Text
  - Permar, SR, Griffin, DE, and Letvin, NL. "Immune containment and consequences of measles virus infection in healthy and immunocompromised individuals." CLINICAL AND VACCINE IMMUNOLOGY 13, no. 4 (April 2006): 437-443. Full Text Link to Item
  - Permar, SR, Klumpp, SA, Mansfield, KG, Carville, AAL, Gorgone, DA, Lifton, MA, Schmitz, JE, Reimann, KA, Polack, FP, Griffin, DE, and Letvin, NL. "Limited contribution of humoral immunity to the clearance of measles viremia in rhesus monkeys." The Journal of Infectious Diseases 190, no. 5 (September 2004): 998-1005. Full Text
  - Permar, SR, Moss, WJ, Ryon, JJ, Douek, DC, Monze, M, and Griffin, DE. "Increased thymic output during acute measles virus infection." Journal of Virology 77, no. 14 (July 2003): 7872-7879. Full Text
  - Permar, SR, Klumpp, SA, Mansfield, KG, Kim, W-K, Gorgone, DA, Lifton, MA, Williams, KC, Schmitz, JE, Reimann, KA, Axthelm, MK, Polack, FP, Griffin, DE, and Letvin, NL. "Role of CD8(+) lymphocytes in control and clearance of measles virus infection of rhesus monkeys." Journal of Virology 77, no. 7 (April 2003): 4396-4400. Full Text
  - Zhang, Y, Permar, S, and Sun, Z. "Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide." Journal of Medical Microbiology 51, no. 1 (January 2002): 42-49. Full Text
  - Permar, SR, Moss, WJ, Ryon, JJ, Monze, M, Cutts, F, Quinn, TC, and Griffin, DE. "Prolonged measles virus shedding in human immunodeficiency virus-infected children, detected by reverse transcriptase-polymerase chain reaction." The Journal of Infectious Diseases 183, no. 4 (February 2001): 532-538. Full Text
  - Polack, FP, Lee, SH, Permar, S, Manyara, E, Nousari, HG, Jeng, Y, Mustafa, F, Valsamakis, A, Adams, RJ, Robinson, HL, and Griffin, DE. "Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles." Nature Medicine 6, no. 7 (2000): 776-781. Full Text
  - Polack, FP, Lee, SH, Permar, S, Manyara, E, Nousari, HG, Jeng, Y, Mustafa, F, Valsamakis, A, Adams, RJ, Robinson, HL, and Griffin, DE. "Erratum: Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles (Nature Medicine (2000) 6 (776-781))." Nature Medicine 6, no. 9 (2000): 1062--. Full Text
  - Cromartie, JD, Mercer, SM, Permar, SR, and Campbell, AM. "Development of the sarcoplasmic reticulum as a calcium pool in early embryonic chicken hearts." MOLECULAR BIOLOGY OF THE CELL 7 (December 1996): 775-775. Link to Item
- Conference Papers
  - Dudley, D, Newman, CM, Mohr, EL, Aliota, MT, Nguyen, SM, Antony, KM, Kohn, S, Simmons, HA, Weiler, AM, Semler, MR, Mohns, MS, Breitbach, ME, Stewart, LM, Koenig, M, Wolfe, B, Salamat, MS, Teixeira, LBC, Zeng, X, Wiepz, GJ, Thoong, TH, Barry, GL, Weisgrau, KL, Vosler, LJ, Rasheed, MN, Graham, ME, Block, L, Post, J, Hayes, JM, Schultz-Darken, N, Schotzko, ML, Eudailey, JA, Kuhn, J, Permar, SR, Rakasz, EG, Capuano, S, Tarantal, AF, Osorio, JE, O'Connor, SL, Friedrich, TC, Golos, TG, and O'Connor, DH. "Nonhuman primate models for Zika virus infection." : WILEY, October 1, 2018. Link to Item
  - Hompe, ED, Kumar, A, Giorgi, EE, McGuire, E, Fouda, GG, Gao, F, and Permar, SR. "Induction of Neutralizing Antibodies Against Autologous Viruses in HIV-1 Infected Pregnant Women Immunized With a gp120/160 Vaccine." HIV Research for Prevention Meeting (HIVR4P) - AIDS Vaccine, Microbicide and ARV-Based Prevention Science. Madrid, SPAIN. October 21, 2018 - October 25, 2018.: MARY ANN LIEBERT, INC, October 1, 2018. Link to Item
  - Martinez, DR, Fong, Y, Li, G, Harrell, EA, Jennewein, M, Weiner, JA, Alter, G, Ackerman, ME, Peng, X, Fouda, GG, and Permar, SR. "Determinants of Transplacental Transfer of Protective Maternal IgG in HIV-infected Women." HIV Research for Prevention Meeting (HIVR4P) - AIDS Vaccine, Microbicide and ARV-Based Prevention Science. Madrid, SPAIN. October 21, 2018 - October 25, 2018.: MARY ANN LIEBERT, INC, October 1, 2018. Link to Item
  - Martinez, DR, Martinez, D, Mangan, RJ, Georgi, E, Chen, J, Mengual, M, Mangold, J, Heimsath, H, Eudailey, JA, Hernandez, G, Morgan-Asiedu, PK, Wiehe, K, Gao, F, and Permar, SR. "Characterizing Env-specific Monoclonal Antibodies Isolated From US and Malawian HIV-infected Non-transmitting and Transmitting Women." HIV Research for Prevention Meeting (HIVR4P) - AIDS Vaccine, Microbicide and ARV-Based Prevention Science. Madrid, SPAIN. October 21, 2018 - October 25, 2018.: MARY ANN LIEBERT, INC, October 1, 2018. Link to Item
  - Nelson, AN, Goswami, R, Dennis, M, Mangan, RJ, Shaw, GM, Bar, KJ, De Paris, K, Van Rompay, KKA, and Permar, SR. "Development of Neutralizing Antibody Responses in SHIV CH505-infected Adult and Infant Rhesus Macaques." HIV Research for Prevention Meeting (HIVR4P) - AIDS Vaccine, Microbicide and ARV-Based Prevention Science. Madrid, SPAIN. October 21, 2018 - October 25, 2018.: MARY ANN LIEBERT, INC, October 1, 2018. Link to Item
  - Pollara, J, Jones, DI, Huffman, T, Dennis, M, Li, G, Goodman, D, Edwards, RW, Kumar, A, LaBranche, CC, Montefiori, DC, Fouda, GG, Tomaras, GD, Ferrari, G, Staats, HF, and Permar, SR. "Bridging Vaccine-induced Antibody Responses in Rabbit and Rhesus Macaque Animal Models." HIV Research for Prevention Meeting (HIVR4P) - AIDS Vaccine, Microbicide and ARV-Based Prevention Science. Madrid, SPAIN. October 21, 2018 - October 25, 2018.: MARY ANN LIEBERT, INC, October 1, 2018. Link to Item
  - Mohr, EL, Dudley, DM, Aliota, MT, Weiler, A, Lehrer-Brey, G, Weisgrau, KL, Mohns, MS, Breitbach, ME, Rasheed, MN, Gellerup, DD, Moncla, LH, Post, J, Schultz-Darken, N, Schotkzo, ML, Hayes, JM, Eudailey, JA, Moody, MA, Permar, SR, O'Connor, SL, Rakasz, EG, Simmons, HA, III, CS, Golos, TG, Osorio, JE, Friedrich, TC, and O'Connor, DH. "DEVELOPMENT OF A NONHUMAN PRIMATE MODEL OF ZIKA VIRUS INFECTION IN PREGNANT AND NON-PREGNANT RHESUS MACAQUES." November 2017. Link to Item
  - Goswami, R, Himes, JE, Jeffries, TL, Mangan, R, Eudailey, J, Jakubowski, H, Nguyen, QN, Aye, P, and Permar, SR. "Effects of breast milk-derived non-broadly neutralizing antibodies on oral SHIV infection in infant rhesus monkeys." August 2017. Link to Item
  - Kaur, A, Nelson, C, Tran, D, Bialas, KM, Blair, R, Gilbert, M, Barry, P, and Permar, SR. "Pre-inoculation infusion with hyperimmune globulin protects against vertical transmission in the rhesus macaque model of congenital CMV infection." August 2017. Link to Item
  - Martinez, DR, McGuire, E, Permar, SR, and Fouda, GG. "Variable IgG Transplacental Transfer in the Setting of Maternal HIV Infection." October 2016. Link to Item
  - Fouda, GG, Cunningham, CK, McFarland, EJ, Borkowsky, W, Muresan, P, Liebl, BE, Liao, H, Haynes, BF, Overman, R, Yates, NL, Tomaras, GD, and Permar, SR. "HIV-1 gp120 Vaccination Elicits a Robust and Durable Anti-V1/V2 IgG Response and Yet No HIV-1 Env-Specific IgA Response in HIV-Exposed Infants." November 1, 2013. Link to Item
  - Kunz, E, Fouda, G, Ho, C, Amos, J, Colvin, L, Montefiori, D, Martelli, A, Allen, A, Aramand, L, Marshall, DJ, Letvin, NL, Staats, H, Pickup, D, Barnett, SC, Moody, MA, Haynes, BF, Liao, H, and Permar, SR. "Combined Mucosal and Systemic C.1086 Envelope Immunization of Lactating Monkeys Induces Potent IgA and Functional IgG Antibody Responses in Milk." November 1, 2013. Link to Item
  - Sacha, CR, Vandergrift, N, Marshall, DJ, Gurley, TC, Stiegel, L, Whitesides, JF, Friedman, J, Fouda, GG, Liebl, B, McGuire, E, Foulger, A, Kepler, TB, Liao, H, Haynes, BF, Moody, MA, and Permar, SR. "Distinct VH Gene Usage and HIV Envelope Specificity of Colostrum and Peripheral B Cell Monoclonal Antibodies of HIV-Infected, Lactating African Women." November 1, 2013. Link to Item
  - Amos, JD, Wilks, AB, Fouda, GG, Smith, SD, Overman, GR, Beck, K, Moody, MA, Tomaras, GD, and Permar, SR. "Strong SIV gp120-specific IgG/IgA responses in milk of African green monkeys may contribute to the rarity of postnatal transmission in this species." : Springer Nature, September 2012. Full Text
  - Salazar-Gonzalez, JF, Salazar, MG, Learn, GH, Kang, HH, Mahlokozera, T, Kalilani, L, Meshnick, SR, Lovingood, RV, Denny, TN, Letvin, NL, Shaw, GM, Hahn, BH, and Permar, SR. "Local production of HIV variants in breast milk of chronically HIV-infected, lactating women." October 2010. Link to Item
Teaching & Mentoring
Recent Courses

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

In the News

Awards & Honors

Global Scholarship

Research

Selected Grants

Selected Publications

Academic Articles

Conference Papers

Recent Courses