Sallie Robey Permar
Wilburt C. Davison Distinguished Professor
Dr. Permar's work focuses on the development of vaccines to prevent vertical transmission of neonatal viral pathogens. She has utilized the nonhuman primate model of HIV/AIDS to characterize the virus-specific immune responses and virus evolution in breast milk and develop a maternal vaccine regimen for protection against breast milk transmission of HIV. In addition, Dr. Permar's lab has advanced the understanding of HIV-specific immune responses and virus evolution in vertically-transmitting and nontransmitting HIV-infected women, defining maternal immune responses that may protect against neonatal transmission of HIV. Importantly, Dr. Permar has established a nonhuman primate model of congenital CMV infection adn is using this model to establish the maternal immune responses that are necessary for protection against placental virus transmission. Finally, Dr. Permar is studying the impact and prevention of postnatal CMV transmission in preterm infants.
Current Appointments & Affiliations
- Wilburt C. Davison Distinguished Professor, Pediatrics, Infectious Diseases, Pediatrics 2020
- Adjunct Professor in the Department of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2020
- Professor in Immunology, Immunology, Basic Science Departments 2017
- Professor of Pathology, Pathology, Clinical Science Departments 2019
- Adjunct Professor in the Department of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2020
- Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2011
- Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2013
- Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2017
- Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2018
Contact Information
- 103020, 2 Genome Ct MSRBII, Durham, NC 27710
- Duke Human Vaccine Institute, Box 103020 MSRBII Rm 3072A, Durham, NC 27710
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sallie.permar@duke.edu
(919) 684-2515
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DHVI - Neonatal Viral Pathogen Immunity Lab
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Permar Lab Website
- Background
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Education, Training, & Certifications
- Fellowship in Pediatric Infectious Diseases, Pediatrics, Children's Hospital Boston 2007 - 2009
- Pediatric Residency, Pediatrics, Children's Hospital Boston 2004 - 2007
- M.D., Harvard Medical School 2004
- Ph.D., Johns Hopkins University 2004
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Duke Appointment History
- Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2017 - 2020
- Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2017 - 2020
- Associate Professor in Immunology, Immunology, Basic Science Departments 2015 - 2017
- Associate Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2015 - 2017
- Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2015 - 2017
- Assistant Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2012 - 2015
- Assistant Professor in Immunology, Immunology, Basic Science Departments 2012 - 2015
- Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2013 - 2015
- Assistant Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2011 - 2013
- Recognition
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In the News
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NOV 24, 2020 -
NOV 6, 2020 School of Medicine -
NOV 5, 2020 Duke Health News -
APR 24, 2020 -
APR 21, 2020 School of Medicine -
APR 14, 2020 -
MAR 10, 2020 -
JAN 31, 2020 -
JUN 13, 2019 Duke Health News -
MAR 5, 2019 Duke Global Health Institute -
JUL 7, 2017 Duke Health News -
JUN 8, 2016 The News & Observer -
FEB 5, 2016 Smithsonian -
FEB 2, 2016 WUNC -
JAN 28, 2016 -
OCT 20, 2015 -
JUN 10, 2015 -
APR 6, 2015 The News & Observer -
APR 21, 2014 The News & Observer -
JAN 5, 2014 -
DEC 30, 2013 News & Observer
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Awards & Honors
- American Society of Clinical Investigation Inductee. ASCI. 2016
- Young Investigator Award. Pediatric Infectious Diseases Society. 2015
- Young Investigator Award. Society for Pediatric Research. 2014
- Young Investigator Award. Society for Pediatrics Research. 2014
- Presidential Early Career Awards for Scientists and Engineers. President of the United States of America. 2012
- Expertise
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Global Scholarship
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Research
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- Research
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Selected Grants
- Duke-UNC Collaborative Pediatric Clinical Pharmacology Postdoctoral Training Program awarded by National Institutes of Health 2021 - 2026
- Duke Center for Advancement of Child Health (CAtCH). awarded by National Institutes of Health 2021 - 2026
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
- Duke Women's Reproductive Health Research Scholars awarded by National Institutes of Health 2020 - 2025
- Immunologic and virologic determinants of congenital Cytomegalovirus transmission and disease in rhesus monkeys awarded by National Institutes of Health 2019 - 2024
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2024
- Immune Correlates of Protection Against Congenital Cytomegalovirus Transmission in an HIV-Infected Mother-Infant Cohort awarded by National Institutes of Health 2020 - 2023
- Duke Preparing Research Scholars in Biomedical Sciences (PRIME) Program awarded by Doris Duke Charitable Foundation, Inc. 2021 - 2023
- Duke Resident Physician-Scientist Program - NIAID awarded by National Institutes of Health 2018 - 2022
- Pediatric Scientist Development Program (K12) awarded by National Institutes of Health 2019 - 2022
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- Recombinant vectored delivery of maternal antibody for transfer into breast milk and across the placenta awarded by Bill and Melinda Gates Foundation 2018 - 2022
- Serologic and genomic modifiers of beta-amyloid levels in an immuno-compromised cohort of adult Down syndrome patients awarded by Infectious Diseases Society of America 2021 - 2022
- Clinical and viral characteristics of maternal cytomegalovirus infection among seropositive pregnant women in the United States awarded by National Institutes of Health 2018 - 2021
- Combined Hepatitis B and HIV-1 Envelope Infant Vaccination to Augment T cell Help through Enhanced Linked Recognition awarded by National Institutes of Health 2017 - 2021
- Research Training in Allergy and Clinical Immunology awarded by National Institutes of Health 2000 - 2021
- Immune Correlates and Mechanisms of Perinatal Cytomegalovirus Infection and Later lLife ALL Development awarded by National Institutes of Health 2019 - 2021
- An orally bioavailable broad-spectrum Hsp90 inhibitor (Hsp90i) therapy to suppress emerging Coronavirus (CoV) infections awarded by Good Ventures Foundation 2020 - 2021
- Innate antiviral factors in breast milk and the oral HIV-1 reservoir awarded by National Institutes of Health 2015 - 2021
- The relationship between maternal ZIKV-specific and ADE antibodies and fetal outcome awarded by National Institutes of Health 2018 - 2021
- Role of neutralizing antibodies in HIV-1-infected and vaccinated mothers in MTCT awarded by National Institutes of Health 2016 - 2021
- Strategies to Target CMV Glycoprotein B Antigenic Domain-2 by B Cell Lineage Maps awarded by National CMV Foundation 2020 - 2021
- Pediatric Scientist Development Program (March of Dimes) awarded by March of Dimes 2020
- Humoral immune correlates of protection against congenital CMV and HSV transmission in HIV-infected women awarded by National Institutes of Health 2019 - 2020
- Zika virus pathophysiology during pregnancy awarded by University of Wisconsin - Madison 2018 - 2020
- The origin, predictors, and immune correlates of viral rebound in orally SHIV infected infant monkeys awarded by National Institutes of Health 2017 - 2020
- International Maternal Pediatric Adolescent AIDS Clinical Trial (IMPAACT) Group awarded by University of California - Los Angeles 2016 - 2020
- Early Life Vaccination to Prevent HIV acquisition during Adolescence awarded by National Institutes of Health 2015 - 2020
- Assessment of diverse anti-HCMV antibody functions elicited by mRNA vaccines expressing the gB and pentameric complex awarded by Moderna Therapeutics, Inc. 2018 - 2020
- Rapid, Near Patient Nucleic Acid Testing for Infant Cytomegalovirus (CMV) Infection awarded by Baebies, Inc 2017 - 2020
- Development of broadly neutralizing antibody responses in HIV-infected children awarded by Doris Duke Charitable Foundation 2018 - 2020
- Antibody and viral determinants of protection against CMV infection in the gB/MF59 vaccination cohort awarded by National Institutes of Health 2017 - 2020
- Antibody and viral determinants of protection against CMV infection following gB/MF59 vaccination awarded by National Institutes of Health 2018 - 2019
- Immune responses during primary CMV infection in pregnancy that correlate with viral containment awarded by Thrasher Research Fund 2018 - 2019
- Identifying key determinants of IgG transplacental transfer from HIV-infected mothers to their fetus awarded by Burroughs Wellcome Fund 2017 - 2019
- Characterization of the immune response to primary CMV infection during pregnancy in a nonhuman primate model and in women enrolled in the MFMU CMV trial (NCT01376778) awarded by Pediatric Infectious Diseases Society 2017 - 2019
- Transmission-blocking potential of novel HIV Env-specific mucosal antibodies awarded by National Institutes of Health 2013 - 2019
- Isolation of protective ZIKV-neutralizing maternal monoclonal antibodies for safe prophylactic use in the preconception period awarded by American Society for Reproductive Medicine 2017 - 2019
- Pregnant rabbits as a model to evaluate the causative role of ZIKV infection in the etiology of congenital malformations awarded by National Institutes of Health 2017 - 2018
- Identifying key determinants that modulate maternal IgG transplacental transfer to the fetus awarded by National Institutes of Health 2017 - 2018
- Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
- Hyperimmune globulin treatment of Zika virus during pregnancy to reduce Congenital Zika Syndrome awarded by University of Wisconsin - Madison 2017 - 2018
- The B cell repertoire and antibody maturation elicited by adjuvanted HIV envelope vaccines in infants awarded by Doris Duke Charitable Foundation 2016 - 2018
- LOC-IMPAACT Leadership Group awarded by Johns Hopkins University 2014 - 2017
- Development of a nonhuman primate model of fetal Zika virus infection and disease awarded by University of California - Davis 2017
- Maternal immune protection against congenital CMV infection awarded by National Institutes of Health 2012 - 2017
- Mucosal vaccination to protect against HIV-1 infection at mucosal sites awarded by National Institutes of Health 2012 - 2017
- Identifying maternal immune correlates of protection against perinatal mother-to-child transmission (MTCT) in a large cohort of clade C HIV infected women awarded by Doris Duke Charitable Foundation 2015 - 2017
- Infant immune correlates of perinatal mother to child transmission of HIV awarded by National Institutes of Health 2015 - 2017
- Permar IMPAACT 2004 stability study QAU awarded by Johns Hopkins University 2014 - 2016
- Simple interventions to Improve Rotavirus Vaccine Effectiveness (SIRVE) awarded by University of North Carolina - Chapel Hill 2014 - 2016
- Pre-infection B cell repertoire primed by the gut commensal bacteria enhances post-infection SIV envelope gp120-specific antibody response in African green monkey awarded by Sigma Xi 2015 - 2016
- Statistical methods for HIV-1 immune correlates studies awarded by Fred Hutchinson Cancer Research Center 2015 - 2016
- HIV Envelope-specific functional antibody responses in HIV-exposed, HIV-vaccinated infants awarded by National Institutes of Health 2012 - 2015
- SIV-specific immunity in breast milk during infection and after vaccination awarded by National Institutes of Health 2009 - 2014
- Mucosal antibody protection against postnatal SIV transmission in natural hosts of SIV awarded by National Institutes of Health 2012 - 2014
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External Relationships
- Baebies, Inc.
- Dynavax Technologies Corporation
- Merck
- Moderna Therapeutics, Inc.
- Pfizer Inc.
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Stark, Ashley, Sarah Cantrell, Rachel G. Greenberg, Sallie R. Permar, and Kristin E. D. Weimer. “Long-term Outcomes after Postnatal Cytomegalovirus Infection in Low Birthweight Preterm Infants: A Systematic Review.” Pediatr Infect Dis J 40, no. 6 (June 1, 2021): 571–81. https://doi.org/10.1097/INF.0000000000003072.Full Text Link to Item
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McElvaine, Allison T., Jacqueline A. Hawkins-Salsbury, Vineet M. Arora, Mark T. Gladwin, James R. Goldenring, David P. Huston, Deborah Krakow, et al. “Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative.” J Clin Invest 131, no. 10 (May 17, 2021). https://doi.org/10.1172/JCI149948.Full Text Open Access Copy Link to Item
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Chahroudi, Ann, and Sallie Permar. “Will We Have the Tools to Address a Reemergent Zika Virus Epidemic?” Ann Intern Med 174, no. 5 (May 2021): 708–9. https://doi.org/10.7326/M21-0397.Full Text Link to Item
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Mangold, Jesse F., Ria Goswami, Ashley N. Nelson, David R. Martinez, Genevieve G. Fouda, and Sallie R. Permar. “Maternal Intervention to Prevent Mother-to-Child Transmission of HIV: Moving Beyond Antiretroviral Therapy.” Pediatr Infect Dis J 40, no. 5S (May 1, 2021): S5–10. https://doi.org/10.1097/INF.0000000000002774.Full Text Link to Item
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Fries, Chelsea N., Elizabeth J. Curvino, Jui-Lin Chen, Sallie R. Permar, Genevieve G. Fouda, and Joel H. Collier. “Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health.” Nat Nanotechnol 16, no. 4 (April 2021): 1–14. https://doi.org/10.1038/s41565-020-0739-9.Full Text Link to Item
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Kumar, Amit, Elena E. Giorgi, Joshua J. Tu, David R. Martinez, Joshua Eudailey, Michael Mengual, Manukumar Honnayakanahalli Marichannegowda, Russell Van Dyke, Feng Gao, and Sallie R. Permar. “Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers.” Plos Pathog 17, no. 4 (April 2021): e1009478. https://doi.org/10.1371/journal.ppat.1009478.Full Text Link to Item
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Itell, Hannah L., Andrew Berenz, Riley J. Mangan, Sallie R. Permar, and David A. Kaufman. “Systemic and mucosal levels of lactoferrin in very low birth weight infants supplemented with bovine lactoferrin.” Biochem Cell Biol 99, no. 1 (February 2021): 25–34. https://doi.org/10.1139/bcb-2020-0238.Full Text Link to Item
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Kaufman, David A., Andrew Berenz, Hannah L. Itell, Mark Conaway, Amy Blackman, James P. Nataro, and Sallie R. Permar. “Dose escalation study of bovine lactoferrin in preterm infants: getting the dose right.” Biochem Cell Biol 99, no. 1 (February 2021): 7–13. https://doi.org/10.1139/bcb-2020-0217.Full Text Link to Item
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Berendam, Stella J., Tiffany M. Styles, Papa K. Morgan-Asiedu, DeAnna Tenney, Amit Kumar, Veronica Obregon-Perko, Katharine J. Bar, et al. “Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses.” J Virol 95, no. 3 (January 13, 2021). https://doi.org/10.1128/JVI.01667-20.Full Text Link to Item
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Obregon-Perko, Veronica, Katherine M. Bricker, Gloria Mensah, Ferzan Uddin, Mithra R. Kumar, Emily J. Fray, Robert F. Siliciano, et al. “Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells.” J Virol 95, no. 2 (December 22, 2020). https://doi.org/10.1128/JVI.01669-20.Full Text Link to Item
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Yiu, Glenn, Sara M. Thomasy, M Isabel Casanova, Alexander Rusakevich, Rebekah I. Keesler, Jennifer Watanabe, Jodie Usachenko, et al. “Evolution of ocular defects in infant macaques following in utero Zika virus infection.” Jci Insight 5, no. 24 (December 17, 2020). https://doi.org/10.1172/jci.insight.143947.Full Text Link to Item
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DeNoble, Anna E., Frances M. Saccoccio, Sallie R. Permar, and Brenna L. Hughes. “Prenatal Treatment of Congenital Cytomegalovirus With Valganciclovir: A Case Report.” Clin Infect Dis 71, no. 9 (December 3, 2020): 2506–8. https://doi.org/10.1093/cid/ciaa305.Full Text Link to Item
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Singh, Tulika, Sarah M. Heston, Stephanie N. Langel, Maria Blasi, Jillian H. Hurst, Genevieve G. Fouda, Matthew S. Kelly, and Sallie R. Permar. “Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies.” Clin Infect Dis 71, no. 8 (November 5, 2020): 2006–13. https://doi.org/10.1093/cid/ciaa547.Full Text Link to Item
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Jenks, Jennifer A., Cody S. Nelson, Hunter K. Roark, Matthew L. Goodwin, Robert F. Pass, David I. Bernstein, Emmanuel B. Walter, et al. “Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans.” Sci Transl Med 12, no. 568 (November 4, 2020). https://doi.org/10.1126/scitranslmed.abb3611.Full Text Link to Item
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Goswami, Ria, Stella J. Berendam, Shuk Hang Li, Ashley N. Nelson, Kristina De Paris, Koen K. A. Van Rompay, Sallie R. Permar, and Genevieve G. Fouda. “Harnessing early life immunity to develop a pediatric HIV vaccine that can protect through adolescence.” Plos Pathog 16, no. 11 (November 2020): e1008983. https://doi.org/10.1371/journal.ppat.1008983.Full Text Link to Item
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Otero, Claire E., Stephanie N. Langel, Maria Blasi, and Sallie R. Permar. “Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries.” Plos Pathog 16, no. 11 (November 2020): e1009010. https://doi.org/10.1371/journal.ppat.1009010.Full Text Link to Item
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Semmes, Eleanor C., Jillian H. Hurst, Kyle M. Walsh, and Sallie R. Permar. “Cytomegalovirus as an immunomodulator across the lifespan.” Curr Opin Virol 44 (October 2020): 112–20. https://doi.org/10.1016/j.coviro.2020.07.013.Full Text Link to Item
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Weimer, Kristin E. D., Sallie R. Permar, and Rachel G. Greenberg. “Association of Postnatal Cytomegalovirus Infection With Head Growth-Reply.” Jama Pediatr 174, no. 10 (October 1, 2020): 1000. https://doi.org/10.1001/jamapediatrics.2020.0244.Full Text Link to Item
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Goodwin, Matthew L., Helen S. Webster, Hsuan-Yuan Wang, Jennifer A. Jenks, Cody S. Nelson, Joshua J. Tu, Jesse F. Mangold, et al. “Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection.” Virology 548 (September 2020): 182–91. https://doi.org/10.1016/j.virol.2020.07.009.Full Text Link to Item
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Barrett, Katherine J., T Michelle Cooley, Alan L. Schwartz, Margaret K. Hostetter, D Wade Clapp, and Sallie R. Permar. “Addressing Gaps in Pediatric Scientist Development: The Department Chair View of 2 AMSPDC-Sponsored Programs.” J Pediatr 222 (July 2020): 7-12.e4. https://doi.org/10.1016/j.jpeds.2020.01.054.Full Text Link to Item
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Post, Annalisa L., Shuk Hang Li, Madison Berry, Hannah Itell, David R. Martinez, Guanhua Xie, Sallie R. Permar, Geeta K. Swamy, and Genevieve G. Fouda. “Efficiency of placental transfer of vaccine-elicited antibodies relative to prenatal Tdap vaccination status.” Vaccine 38, no. 31 (June 26, 2020): 4869–76. https://doi.org/10.1016/j.vaccine.2020.05.036.Full Text Link to Item
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Hompe, Eliza D., Jesse F. Mangold, Amit Kumar, Joshua A. Eudailey, Erin McGuire, Barton F. Haynes, M Anthony Moody, et al. “Induction of Neutralizing Responses against Autologous Virus in Maternal HIV Vaccine Trials.” Msphere 5, no. 3 (June 3, 2020). https://doi.org/10.1128/mSphere.00254-20.Full Text Link to Item
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Berendam, Stella J., Ashley N. Nelson, Ria Goswami, Deborah Persaud, Nancy L. Haigwood, Ann Chahroudi, Genevieve G. Fouda, and Sallie R. Permar. “Pediatric HIV: the Potential of Immune Therapeutics to Achieve Viral Remission and Functional Cure.” Curr Hiv/Aids Rep 17, no. 3 (June 2020): 237–48. https://doi.org/10.1007/s11904-020-00495-1.Full Text Link to Item
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Nelson, Cody S., Jennifer A. Jenks, Norbert Pardi, Matthew Goodwin, Hunter Roark, Whitney Edwards, Jason S. McLellan, Justin Pollara, Drew Weissman, and Sallie R. Permar. “Human Cytomegalovirus Glycoprotein B Nucleoside-Modified mRNA Vaccine Elicits Antibody Responses with Greater Durability and Breadth than MF59-Adjuvanted gB Protein Immunization.” J Virol 94, no. 9 (April 16, 2020). https://doi.org/10.1128/JVI.00186-20.Full Text Link to Item
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Curtis, Alan D., Maria Dennis, Joshua Eudailey, Korey L. Walter, Kenneth Cronin, S Munir Alam, Neelima Choudhary, et al. “HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy.” Msphere 5, no. 2 (March 25, 2020). https://doi.org/10.1128/mSphere.00162-20.Full Text Link to Item
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Martinez, David R., Joshua J. Tu, Amit Kumar, Jesse F. Mangold, Riley J. Mangan, Ria Goswami, Elena E. Giorgi, et al. “Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants.” Mbio 11, no. 2 (March 10, 2020). https://doi.org/10.1128/mBio.00176-20.Full Text Link to Item
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Nelson, Cody S., Ilona Baraniak, Daniele Lilleri, Matthew B. Reeves, Paul D. Griffiths, and Sallie R. Permar. “Immune Correlates of Protection Against Human Cytomegalovirus Acquisition, Replication, and Disease.” J Infect Dis 221, no. Suppl 1 (March 5, 2020): S45–59. https://doi.org/10.1093/infdis/jiz428.Full Text Link to Item
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Roark, Hunter K., Jennifer A. Jenks, Sallie R. Permar, and Mark R. Schleiss. “Animal Models of Congenital Cytomegalovirus Transmission: Implications for Vaccine Development.” J Infect Dis 221, no. Suppl 1 (March 5, 2020): S60–73. https://doi.org/10.1093/infdis/jiz484.Full Text Link to Item
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Permar, Sallie R., Rebecca A. Ward, Katherine J. Barrett, Stephanie A. Freel, Rasheed A. Gbadegesin, Christopher D. Kontos, Patrick J. Hu, Katherine E. Hartmann, Christopher S. Williams, and Jatin M. Vyas. “Addressing the physician-scientist pipeline: strategies to integrate research into clinical training programs.” J Clin Invest 130, no. 3 (March 2, 2020): 1058–61. https://doi.org/10.1172/JCI136181.Full Text Link to Item
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Langel, Stephanie N., Claire E. Otero, David R. Martinez, and Sallie R. Permar. “Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection.” Plos Pathog 16, no. 3 (March 2020): e1008303. https://doi.org/10.1371/journal.ppat.1008303.Full Text Link to Item
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Martinez, David R., Joshua J. Tu, Amit Kumar, Jesse F. Mangold, Riley J. Mangan, Ria Goswami, Elena E. Giorgi, et al. “Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants.” Mbio 11, no. 2 (March 1, 2020). https://doi.org/10.1128/mBio.00176.20.Full Text Link to Item
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Weimer, Kristin E. D., Hunter Roark, Kimberley Fisher, C Michael Cotten, David A. Kaufman, Margarita Bidegain, and Sallie R. Permar. “Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection.” Am J Perinatol, February 18, 2020. https://doi.org/10.1055/s-0040-1701609.Full Text Link to Item
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Han, Qifeng, Todd Bradley, Wilton B. Williams, Derek W. Cain, David C. Montefiori, Kevin O. Saunders, Robert J. Parks, et al. “Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization.” Cell Rep 30, no. 5 (February 4, 2020): 1553-1569.e6. https://doi.org/10.1016/j.celrep.2019.12.091.Full Text Open Access Copy Link to Item
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Cable, Jennifer, Padmini Srikantiah, James E. Crowe, Bali Pulendran, Adrian Hill, Ann Ginsberg, Wayne Koff, et al. “Vaccine innovations for emerging infectious diseases-a symposium report.” Ann N Y Acad Sci 1462, no. 1 (February 2020): 14–26. https://doi.org/10.1111/nyas.14235.Full Text Link to Item
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Vera Cruz, Diana, Cody S. Nelson, Dollnovan Tran, Peter A. Barry, Amitinder Kaur, Katia Koelle, and Sallie R. Permar. “Intrahost cytomegalovirus population genetics following antibody pretreatment in a monkey model of congenital transmission.” Plos Pathog 16, no. 2 (February 2020): e1007968. https://doi.org/10.1371/journal.ppat.1007968.Full Text Link to Item
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Weimer, Kristin E. D., Matthew S. Kelly, Sallie R. Permar, Reese H. Clark, and Rachel G. Greenberg. “Association of Adverse Hearing, Growth, and Discharge Age Outcomes With Postnatal Cytomegalovirus Infection in Infants With Very Low Birth Weight.” Jama Pediatr 174, no. 2 (February 1, 2020): 133–40. https://doi.org/10.1001/jamapediatrics.2019.4532.Full Text Link to Item
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Fouda, Genevieve G., Kristina De Paris, Ofer Levy, Arnaud Marchant, Glenda Gray, Sallie Permar, Mary Marovich, and Anjali Singh. “Immunological mechanisms of inducing HIV immunity in infants.” Vaccine 38, no. 3 (January 16, 2020): 411–15. https://doi.org/10.1016/j.vaccine.2019.11.011.Full Text Link to Item
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Kazimbaya, Katayi Mwila, Caroline C. Chisenga, Michelo Simuyandi, Cynthia Mubanga Phiri, Natasha Makabilo Laban, Samuel Bosomprah, Sallie R. Permar, Sody Munsaka, and Roma Chilengi. “In-vitro inhibitory effect of maternal breastmilk components on rotavirus vaccine replication and association with infant seroconversion to live oral rotavirus vaccine.” Plos One 15, no. 11 (2020): e0240714. https://doi.org/10.1371/journal.pone.0240714.Full Text Link to Item
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Koenig, Michelle R., Elaina Razo, Ann Mitzey, Christina M. Newman, Dawn M. Dudley, Meghan E. Breitbach, Matthew R. Semler, et al. “Quantitative definition of neurobehavior, vision, hearing and brain volumes in macaques congenitally exposed to Zika virus.” Plos One 15, no. 10 (2020): e0235877. https://doi.org/10.1371/journal.pone.0235877.Full Text Link to Item
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Pollara, Justin, R Whitney Edwards, Shalini Jha, Chia-Ying Kao Lam, Liqin Liu, Gundo Diedrich, Jeffrey L. Nordstrom, et al. “Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules.” Front Immunol 11 (2020): 713. https://doi.org/10.3389/fimmu.2020.00713.Full Text Open Access Copy Link to Item
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Semmes, Eleanor C., Jui-Lin Chen, Ria Goswami, Trevor D. Burt, Sallie R. Permar, and Genevieve G. Fouda. “Understanding Early-Life Adaptive Immunity to Guide Interventions for Pediatric Health.” Front Immunol 11 (2020): 595297. https://doi.org/10.3389/fimmu.2020.595297.Full Text Link to Item
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Singh, Tulika, Claire E. Otero, Katherine Li, Sarah M. Valencia, Ashley N. Nelson, and Sallie R. Permar. “Vaccines for Perinatal and Congenital Infections-How Close Are We?” Front Pediatr 8 (2020): 569. https://doi.org/10.3389/fped.2020.00569.Full Text Link to Item
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Yamey, G., R. Young, T. Bekele, A. Gunn, N. Chapman, V. Chowdhary, K. Corrigan, et al. “Developing new health technologies for neglected diseases: A pipeline portfolio review and cost model.” Gates Open Research 2 (January 1, 2020). https://doi.org/10.12688/gatesopenres.12817.3.Full Text
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Van Rompay, Koen K. A., Rebekah I. Keesler, Amir Ardeshir, Jennifer Watanabe, Jodie Usachenko, Anil Singapuri, Christina Cruzen, et al. “DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.” Sci Transl Med 11, no. 523 (December 18, 2019). https://doi.org/10.1126/scitranslmed.aay2736.Full Text Link to Item
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Ezekian, Brian, Paul M. Schroder, Michael S. Mulvihill, Andrew Barbas, Bradley Collins, Kyle Freischlag, Janghoon Yoon, et al. “Pretransplant Desensitization with Costimulation Blockade and Proteasome Inhibitor Reduces DSA and Delays Antibody-Mediated Rejection in Highly Sensitized Nonhuman Primate Kidney Transplant Recipients.” J Am Soc Nephrol 30, no. 12 (December 2019): 2399–2411. https://doi.org/10.1681/ASN.2019030304.Full Text Link to Item
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Hompe, Eliza D., Denise L. Jacobson, Joshua A. Eudailey, Kevin Butler, Whitney Edwards, Justin Pollara, Sean S. Brummel, et al. “Maternal Humoral Immune Responses Do Not Predict Postnatal HIV-1 Transmission Risk in Antiretroviral-Treated Mothers from the IMPAACT PROMISE Study.” Msphere 4, no. 5 (October 23, 2019). https://doi.org/10.1128/mSphere.00716-19.Full Text Link to Item
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Coppola, Tiziana, Jesse F. Mangold, Sarah Cantrell, and Sallie R. Permar. “Impact of Maternal Immunity on Congenital Cytomegalovirus Birth Prevalence and Infant Outcomes: A Systematic Review.” Vaccines (Basel) 7, no. 4 (September 26, 2019). https://doi.org/10.3390/vaccines7040129.Full Text Link to Item
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Goswami, Ria, Ashley N. Nelson, Joshua J. Tu, Maria Dennis, Liqi Feng, Amit Kumar, Jesse Mangold, et al. “Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model.” Mbio 10, no. 5 (September 5, 2019). https://doi.org/10.1128/mBio.01971-19.Full Text Link to Item
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Maness, Nicholas J., Blake Schouest, Anil Singapuri, Maria Dennis, Margaret H. Gilbert, Rudolf P. Bohm, Faith Schiro, et al. “Postnatal Zika virus infection of nonhuman primate infants born to mothers infected with homologous Brazilian Zika virus.” Sci Rep 9, no. 1 (September 5, 2019): 12802. https://doi.org/10.1038/s41598-019-49209-7.Full Text Link to Item
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Breitbach, Meghan E., Christina M. Newman, Dawn M. Dudley, Laurel M. Stewart, Matthew T. Aliota, Michelle R. Koenig, Phoenix M. Shepherd, et al. “Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques.” Plos Pathog 15, no. 8 (August 2019): e1007766. https://doi.org/10.1371/journal.ppat.1007766.Full Text Link to Item
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Hurst, Jillian H., Katherine J. Barrett, Matthew S. Kelly, Betty B. Staples, Kathleen A. McGann, Coleen K. Cunningham, Ann M. Reed, Rasheed A. Gbadegesin, and Sallie R. Permar. “Cultivating Research Skills During Clinical Training to Promote Pediatric-Scientist Development.” Pediatrics 144, no. 2 (August 2019). https://doi.org/10.1542/peds.2019-0745.Full Text Open Access Copy Link to Item
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Nelson, Ashley N., Ria Goswami, Maria Dennis, Joshua Tu, Riley J. Mangan, Pooja T. Saha, Derek W. Cain, et al. “Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.” J Virol 93, no. 15 (August 1, 2019). https://doi.org/10.1128/JVI.00168-19.Full Text Link to Item
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Singh, Tulika, Cesar A. Lopez, Camila Giuberti, Maria L. Dennis, Hannah L. Itell, Holly J. Heimsath, Helen S. Webster, et al. “Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy.” Plos Negl Trop Dis 13, no. 8 (August 2019): e0007648. https://doi.org/10.1371/journal.pntd.0007648.Full Text Link to Item
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Saccoccio, Frances M., Jennifer A. Jenks, Hannah L. Itell, Shuk Hang Li, Madison Berry, Justin Pollara, Corey Casper, Soren Gantt, and Sallie R. Permar. “Humoral Immune Correlates for Prevention of Postnatal Cytomegalovirus Acquisition.” J Infect Dis 220, no. 5 (July 31, 2019): 772–80. https://doi.org/10.1093/infdis/jiz192.Full Text Link to Item
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Singh, Anjali, Sallie Permar, Tobias R. Kollmann, Ofer Levy, Mary Marovich, and Kristina De Paris. “AIDS Vaccine Research Subcommittee (AVRS) Consultation: Early-Life Immunization Strategies against HIV Acquisition.” Msphere 4, no. 4 (July 17, 2019). https://doi.org/10.1128/mSphere.00320-19.Full Text Link to Item
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Jones, Dorothy I., Justin J. Pollara, Brandi T. Johnson-Weaver, Celia C. LaBranche, David C. Montefiori, David J. Pickup, Sallie R. Permar, et al. “Optimized Mucosal Modified Vaccinia Virus Ankara Prime/Soluble gp120 Boost HIV Vaccination Regimen Induces Antibody Responses Similar to Those of an Intramuscular Regimen.” J Virol 93, no. 14 (July 15, 2019). https://doi.org/10.1128/JVI.00475-19.Full Text Link to Item
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Mangan, Riley J., Lisa Stamper, Tomoo Ohashi, Joshua A. Eudailey, Eden P. Go, Frederick H. Jaeger, Hannah L. Itell, et al. “Determinants of Tenascin-C and HIV-1 envelope binding and neutralization.” Mucosal Immunol 12, no. 4 (July 2019): 1004–12. https://doi.org/10.1038/s41385-019-0164-2.Full Text Link to Item
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Martinez, David R., Youyi Fong, Shuk Hang Li, Fang Yang, Madeleine F. Jennewein, Joshua A. Weiner, Erin A. Harrell, et al. “Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women.” Cell 178, no. 1 (June 27, 2019): 190-201.e11. https://doi.org/10.1016/j.cell.2019.05.046.Full Text Link to Item
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Pollara, Justin, Dorothy I. Jones, Tori Huffman, R Whitney Edwards, Maria Dennis, Shuk Hang Li, Shalini Jha, et al. “Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” J Virol 93, no. 10 (May 15, 2019). https://doi.org/10.1128/JVI.02119-18.Full Text Link to Item
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Tay, Matthew Zirui, Erika L. Kunz, Aaron Deal, Lu Zhang, Kelly E. Seaton, Wes Rountree, Joshua A. Eudailey, et al. “Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.” J Virol 93, no. 7 (April 1, 2019). https://doi.org/10.1128/JVI.02084-18.Full Text Link to Item
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Burghuber, Christopher K., Miriam Manook, Brian Ezekian, Adriana C. Gibby, Frank V. Leopardi, Minqing Song, Jennifer Jenks, et al. “Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients.” Am J Transplant 19, no. 3 (March 2019): 724–36. https://doi.org/10.1111/ajt.15067.Full Text Link to Item
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Dennis, Maria, Joshua Eudailey, Justin Pollara, Arthur S. McMillan, Kenneth D. Cronin, Pooja T. Saha, Alan D. Curtis, et al. “Coadministration of CH31 Broadly Neutralizing Antibody Does Not Affect Development of Vaccine-Induced Anti-HIV-1 Envelope Antibody Responses in Infant Rhesus Macaques.” J Virol 93, no. 5 (March 1, 2019). https://doi.org/10.1128/JVI.01783-18.Full Text Link to Item
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Nelson, Cody S., Diana Vera Cruz, Melody Su, Guanhua Xie, Nathan Vandergrift, Robert F. Pass, Michael Forman, et al. “Intrahost Dynamics of Human Cytomegalovirus Variants Acquired by Seronegative Glycoprotein B Vaccinees.” J Virol 93, no. 5 (March 1, 2019). https://doi.org/10.1128/JVI.01695-18.Full Text Link to Item
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Wyatt, Lauren, Sallie Robey Permar, Ernesto Ortiz, Axel Berky, Christopher W. Woods, Genevieve Fouda Amouou, Hannah Itell, Heileen Hsu-Kim, and William Pan. “Mercury Exposure and Poor Nutritional Status Reduce Response to Six Expanded Program on Immunization Vaccines in Children: An Observational Cohort Study of Communities Affected by Gold Mining in the Peruvian Amazon.” Int J Environ Res Public Health 16, no. 4 (February 21, 2019). https://doi.org/10.3390/ijerph16040638.Full Text Link to Item
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Jenks, Jennifer A., Matthew L. Goodwin, and Sallie R. Permar. “The Roles of Host and Viral Antibody Fc Receptors in Herpes Simplex Virus (HSV) and Human Cytomegalovirus (HCMV) Infections and Immunity.” Front Immunol 10 (2019): 2110. https://doi.org/10.3389/fimmu.2019.02110.Full Text Link to Item
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Nelson, Cody S., Genevieve G. A. Fouda, and Sallie R. Permar. “Pediatric HIV-1 Acquisition and Lifelong Consequences of Infant Infection.” Curr Immunol Rev 15, no. 1 (2019): 131–38. https://doi.org/10.2174/1573395514666180531074047.Full Text Link to Item
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Shah, Spandan V., Cordelia Manickam, Daniel R. Ram, Kyle Kroll, Hannah Itell, Sallie R. Permar, Dan H. Barouch, Nichole R. Klatt, and R Keith Reeves. “CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques.” Cell Rep 25, no. 10 (December 4, 2018): 2766-2774.e3. https://doi.org/10.1016/j.celrep.2018.11.020.Full Text Link to Item
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Himes, Jonathon E., Ria Goswami, Riley J. Mangan, Amit Kumar, Thomas L. Jeffries, Joshua A. Eudailey, Holly Heimsath, et al. “Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys.” Mucosal Immunol 11, no. 6 (November 2018): 1716–26. https://doi.org/10.1038/s41385-018-0067-7.Full Text Link to Item
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Phillips, Bonnie, Koen K. A. Van Rompay, Jennifer Rodriguez-Nieves, Clarisse Lorin, Marguerite Koutsoukos, Mark Tomai, Christopher B. Fox, et al. “Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques.” J Virol 92, no. 20 (October 15, 2018). https://doi.org/10.1128/JVI.01051-18.Full Text Link to Item
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Lantos, Paul M., Gabriela Maradiaga-Panayotti, Xavier Barber, Eileen Raynor, Debara Tucci, Kate Hoffman, Sallie R. Permar, et al. “Geographic and Racial Disparities in Infant Hearing Loss.” Otolaryngol Head Neck Surg, October 9, 2018, 194599818803305. https://doi.org/10.1177/0194599818803305.Full Text Open Access Copy Link to Item
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Permar, Sallie, Ofer Levy, Tobias R. Kollman, Anjali Singh, and Kristina De Paris. “Early Life HIV-1 Immunization: Providing a Window for Protection Before Sexual Debut.” Aids Res Hum Retroviruses 34, no. 10 (October 2018): 823–27. https://doi.org/10.1089/AID.2018.0018.Full Text Link to Item
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Itell, Hannah L., Erin P. McGuire, Petronella Muresan, Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Sallie R. Permar, and Genevieve G. Fouda. “Development and application of a multiplex assay for the simultaneous measurement of antibody responses elicited by common childhood vaccines.” Vaccine 36, no. 37 (September 5, 2018): 5600–5608. https://doi.org/10.1016/j.vaccine.2018.07.048.Full Text Link to Item
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Lantos, Paul M., Kate Hoffman, Sallie R. Permar, Pearce Jackson, Brenna L. Hughes, Amy Kind, and Geeta Swamy. “Neighborhood Disadvantage is Associated with High Cytomegalovirus Seroprevalence in Pregnancy.” J Racial Ethn Health Disparities 5, no. 4 (August 2018): 782–86. https://doi.org/10.1007/s40615-017-0423-4.Full Text Open Access Copy Link to Item
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Martinez, David R., Genevieve G. Fouda, Xinxia Peng, Margaret E. Ackerman, and Sallie R. Permar. “Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?” Plos Pathog 14, no. 8 (August 2018): e1007161. https://doi.org/10.1371/journal.ppat.1007161.Full Text Link to Item
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Permar, Sallie R., Mark R. Schleiss, and Stanley A. Plotkin. “Reply to Gantt et al., "Higher Expectations for a Vaccine To Prevent Congenital Cytomegalovirus Infection".” J Virol 92, no. 15 (August 1, 2018). https://doi.org/10.1128/JVI.00771-18.Full Text Link to Item
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Coffey, Lark L., Rebekah I. Keesler, Patricia A. Pesavento, Kevin Woolard, Anil Singapuri, Jennifer Watanabe, Christina Cruzen, et al. “Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease.” Nat Commun 9, no. 1 (June 20, 2018): 2414. https://doi.org/10.1038/s41467-018-04777-6.Full Text Link to Item
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Nelson, Cody S., Tori Huffman, Jennifer A. Jenks, Eduardo Cisneros de la Rosa, Guanhua Xie, Nathan Vandergrift, Robert F. Pass, Justin Pollara, and Sallie R. Permar. “HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions.” Proc Natl Acad Sci U S A 115, no. 24 (June 12, 2018): 6267–72. https://doi.org/10.1073/pnas.1800177115.Full Text Link to Item
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Jegaskanda, Sinthujan, Rosemarie D. Mason, Sarah F. Andrews, Adam K. Wheatley, Ruijun Zhang, Glennys V. Reynoso, David R. Ambrozak, et al. “Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes.” J Virol 92, no. 9 (May 1, 2018). https://doi.org/10.1128/JVI.01970-17.Full Text Link to Item
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Ram, Daniel R., Cordelia Manickam, Brady Hueber, Hannah L. Itell, Sallie R. Permar, Valerie Varner, and R Keith Reeves. “Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques.” Plos Pathog 14, no. 5 (May 2018): e1007104. https://doi.org/10.1371/journal.ppat.1007104.Full Text Link to Item
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Kumar, Amit, Claire E. P. Smith, Elena E. Giorgi, Joshua Eudailey, David R. Martinez, Karina Yusim, Ayooluwa O. Douglas, et al. “Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.” Plos Pathog 14, no. 4 (April 2018): e1006944. https://doi.org/10.1371/journal.ppat.1006944.Full Text Link to Item
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Permar, Sallie R., Mark R. Schleiss, and Stanley A. Plotkin. “Advancing Our Understanding of Protective Maternal Immunity as a Guide for Development of Vaccines To Reduce Congenital Cytomegalovirus Infections.” J Virol 92, no. 7 (April 1, 2018). https://doi.org/10.1128/JVI.00030-18.Full Text Link to Item
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Nguyen, Quang N., David R. Martinez, Jonathon E. Himes, R. Whitney Edwards, Qifeng Han, Amit Kumar, Riley Mangan, et al. “Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.” Retrovirology 15, no. 1 (March 9, 2018): 24. https://doi.org/10.1186/s12977-018-0406-5.Full Text Link to Item
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Premkumar, Lakshmanane, Matthew Collins, Stephen Graham, Guei-Jiun Alice Liou, Cesar A. Lopez, Ramesh Jadi, Angel Balmaseda, et al. “Development of Envelope Protein Antigens To Serologically Differentiate Zika Virus Infection from Dengue Virus Infection.” J Clin Microbiol 56, no. 3 (March 2018). https://doi.org/10.1128/JCM.01504-17.Full Text Link to Item
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Eudailey, Joshua A., Maria L. Dennis, Morgan E. Parker, Bonnie L. Phillips, Tori N. Huffman, Camden P. Bay, Michael G. Hudgens, et al. “Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.” Msphere 3, no. 1 (January 2018). https://doi.org/10.1128/mSphere.00505-17.Full Text Open Access Copy Link to Item
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Fouda, Genevieve G., David R. Martinez, Geeta K. Swamy, and Sallie R. Permar. “The Impact of IgG transplacental transfer on early life immunity.” Immunohorizons 2, no. 1 (January 1, 2018): 14–25. https://doi.org/10.4049/immunohorizons.1700057.Full Text Link to Item
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Kaur, Amitinder, Hannah L. Itell, E Peek Ehlinger, Valerie Varner, Soren Gantt, and Sallie R. Permar. “Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys.” Plos One 13, no. 10 (2018): e0206330. https://doi.org/10.1371/journal.pone.0206330.Full Text Link to Item
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McGuire, Erin P., Youyi Fong, Christopher Toote, Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Susan Barnett, et al. “HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.” J Virol 92, no. 1 (January 1, 2018). https://doi.org/10.1128/JVI.01070-17.Full Text Link to Item
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Nelson, Cody S., Betsy C. Herold, and Sallie R. Permar. “A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection.” Npj Vaccines 3 (2018): 38. https://doi.org/10.1038/s41541-018-0074-4.Full Text Link to Item
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Itell, Hannah L., Cody S. Nelson, David R. Martinez, and Sallie R. Permar. “Maternal immune correlates of protection against placental transmission of cytomegalovirus.” Placenta 60 Suppl 1 (December 2017): S73–79. https://doi.org/10.1016/j.placenta.2017.04.011.Full Text Link to Item
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Schleiss, Mark R., Sallie R. Permar, and Stanley A. Plotkin. “Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection.” Clin Vaccine Immunol 24, no. 12 (December 2017). https://doi.org/10.1128/CVI.00268-17.Full Text Link to Item
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Voronin, Yegor, Ilesh Jani, Barney S. Graham, Coleen K. Cunningham, Lynne M. Mofenson, Philippa M. Musoke, Sallie R. Permar, and Gabriella Scarlatti. “Recent progress in immune-based interventions to prevent HIV-1 transmission to children.” J Int Aids Soc 20, no. 4 (December 2017). https://doi.org/10.1002/jia2.25038.Full Text Link to Item
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Han, Qifeng, Wilton B. Williams, Kevin O. Saunders, Kelly E. Seaton, Kevin J. Wiehe, Nathan Vandergrift, Tarra A. Von Holle, et al. “HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques.” J Virol 91, no. 21 (November 1, 2017). https://doi.org/10.1128/JVI.00923-17.Full Text Link to Item
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Fong, Youyi, Ying Huang, Peter B. Gilbert, and Sallie R. Permar. “chngpt: threshold regression model estimation and inference.” Bmc Bioinformatics 18, no. 1 (October 16, 2017): 454. https://doi.org/10.1186/s12859-017-1863-x.Full Text Link to Item
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Lantos, Paul M., Kate Hoffman, Sallie R. Permar, Pearce Jackson, Brenna L. Hughes, and Geeta K. Swamy. “Geographic Disparities in Cytomegalovirus Infection During Pregnancy.” J Pediatric Infect Dis Soc 6, no. 3 (September 1, 2017): e55–61. https://doi.org/10.1093/jpids/piw088.Full Text Link to Item
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Itell, Hannah L., Amitinder Kaur, Jesse D. Deere, Peter A. Barry, and Sallie R. Permar. “Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections.” Curr Opin Virol 25 (August 2017): 126–33. https://doi.org/10.1016/j.coviro.2017.08.005.Full Text Link to Item
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Mutucumarana, Charmaine P., Joshua Eudailey, Erin P. McGuire, Nathan Vandergrift, Gerald Tegha, Charles Chasela, Sascha Ellington, et al. “Maternal Humoral Immune Correlates of Peripartum Transmission of Clade C HIV-1 in the Setting of Peripartum Antiretrovirals.” Clin Vaccine Immunol 24, no. 8 (August 2017). https://doi.org/10.1128/CVI.00062-17.Full Text Link to Item
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Nelson, Cody S., Diana Vera Cruz, Dollnovan Tran, Kristy M. Bialas, Lisa Stamper, Huali Wu, Margaret Gilbert, et al. “Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.” Jci Insight 2, no. 13 (July 6, 2017). https://doi.org/10.1172/jci.insight.94002.Full Text Link to Item
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Fan, Qihua, Cody S. Nelson, Kristy M. Bialas, Flavia Chiuppesi, Joshua Amos, Thaddeus C. Gurley, Dawn Jones Marshall, et al. “Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.” Clin Vaccine Immunol 24, no. 5 (May 2017). https://doi.org/10.1128/CVI.00510-16.Full Text Link to Item
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Martinez, David R., Nathan Vandergrift, Ayooluwa O. Douglas, Erin McGuire, John Bainbridge, Nathan I. Nicely, David C. Montefiori, Georgia D. Tomaras, Genevieve G. Fouda, and Sallie R. Permar. “Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk.” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.02422-16.Full Text Link to Item
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Nguyen, Sydney M., Kathleen M. Antony, Dawn M. Dudley, Sarah Kohn, Heather A. Simmons, Bryce Wolfe, M Shahriar Salamat, et al. “Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques.” Plos Pathog 13, no. 5 (May 2017): e1006378. https://doi.org/10.1371/journal.ppat.1006378.Full Text Link to Item
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Becker-Dreps, Sylvia, Wan Suk Choi, Lisa Stamper, Samuel Vilchez, Daniel E. Velasquez, Sung-Sil Moon, Michael G. Hudgens, Baoming Jiang, and Sallie R. Permar. “Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants.” J Pediatric Infect Dis Soc 6, no. 1 (March 1, 2017): 87–90. https://doi.org/10.1093/jpids/piv076.Full Text Link to Item
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Douglas, Ayooluwa O., David R. Martinez, and Sallie R. Permar. “The Role of Maternal HIV Envelope-Specific Antibodies and Mother-to-Child Transmission Risk.” Front Immunol 8 (2017): 1091. https://doi.org/10.3389/fimmu.2017.01091.Full Text Link to Item
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Fouda, Genevieve G., Joshua Eudailey, Erika L. Kunz, Joshua D. Amos, Brooke E. Liebl, Jonathan Himes, Felix Boakye-Agyeman, et al. “Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization.” Mucosal Immunol 10, no. 1 (January 2017): 228–37. https://doi.org/10.1038/mi.2016.32.Full Text Link to Item
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Mwila, Katayi, Roma Chilengi, Michelo Simuyandi, Sallie R. Permar, and Sylvia Becker-Dreps. “Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries.” Clin Vaccine Immunol 24, no. 1 (January 2017). https://doi.org/10.1128/CVI.00405-16.Full Text Link to Item
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Mwila-Kazimbaya, Katayi, Miguel Pugliese Garcia, Samuel Bosomprah, Natasha Makabilo Laban, Caroline Cleopatra Chisenga, Sallie Robey Permar, Michelo Simuyandi, Sody Munsaka, and Roma Chilengi. “Effect of innate antiviral glycoproteins in breast milk on seroconversion to rotavirus vaccine (Rotarix) in children in Lusaka, Zambia.” Plos One 12, no. 12 (2017): e0189351. https://doi.org/10.1371/journal.pone.0189351.Full Text Link to Item
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Bialas, Kristy M., Daniel Westreich, Eduardo Cisneros de la Rosa, Cody S. Nelson, Lawrence M. Kauvar, Tong-Ming Fu, and Sallie R. Permar. “Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants.” J Infect Dis 214, no. 12 (December 15, 2016): 1916–23. https://doi.org/10.1093/infdis/jiw487.Full Text Link to Item
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Aliota, Matthew T., Dawn M. Dudley, Christina M. Newman, Emma L. Mohr, Dane D. Gellerup, Meghan E. Breitbach, Connor R. Buechler, et al. “Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques.” Plos Negl Trop Dis 10, no. 12 (December 2016): e0005168. https://doi.org/10.1371/journal.pntd.0005168.Full Text Link to Item
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Nguyen, Quang N., Jonathon E. Himes, David R. Martinez, and Sallie R. Permar. “The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy.” Plos Pathog 12, no. 12 (December 2016): e1005997. https://doi.org/10.1371/journal.ppat.1005997.Full Text Link to Item
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Himes, Jonathon E., Carrie Ho, Quang N. Nguyen, Joshua D. Amos, Haolin Xu, Cliburn Chan, Shein-Chung Chow, et al. “Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys.” J Virol 90, no. 19 (October 1, 2016): 8795–8808. https://doi.org/10.1128/JVI.00701-16.Full Text Link to Item
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Zhang, Ruijun, S Munir Alam, Jae-Sung Yu, Richard Scearce, Bradley Lockwood, Kwan-Ki Hwang, Robert Parks, et al. “Novel Monoclonal Antibodies for Studies of Human and Rhesus Macaque Secretory Component and Human J-Chain.” Monoclon Antib Immunodiagn Immunother 35, no. 4 (August 2016): 217–26. https://doi.org/10.1089/mab.2016.0014.Full Text Link to Item
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Zhang, Ruijun, David R. Martinez, Quang N. Nguyen, Justin Pollara, Trina Arifin, Christina Stolarchuk, Andrew Foulger, et al. “Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus.” Nat Commun 7 (July 6, 2016): 12131. https://doi.org/10.1038/ncomms12131.Full Text Link to Item
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Mukhopadhyay, Sagori, Sarah A. Meyer, Sallie R. Permar, and Karen M. Puopolo. “Symptomatic Postnatal Cytomegalovirus Testing among Very Low-Birth-Weight Infants: Indications and Outcomes.” Am J Perinatol 33, no. 9 (July 2016): 894–902. https://doi.org/10.1055/s-0036-1581080.Full Text Link to Item
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Dudley, Dawn M., Matthew T. Aliota, Emma L. Mohr, Andrea M. Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, et al. “A rhesus macaque model of Asian-lineage Zika virus infection.” Nat Commun 7 (June 28, 2016): 12204. https://doi.org/10.1038/ncomms12204.Full Text Link to Item
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Nelson, Cody S., Justin Pollara, Erika L. Kunz, Thomas L. Jeffries, Ryan Duffy, Charles Beck, Lisa Stamper, et al. “Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk.” J Virol 90, no. 10 (May 15, 2016): 4951–65. https://doi.org/10.1128/JVI.00335-16.Full Text Link to Item
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Jeffries, T. L., C. R. Sacha, J. Pollara, J. Himes, F. H. Jaeger, S. M. Dennison, E. McGuire, et al. “The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells.” Mucosal Immunol 9, no. 2 (March 2016): 414–27. https://doi.org/10.1038/mi.2015.70.Full Text Link to Item
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Bialas, Kristy M., and Sallie R. Permar. “The March towards a Vaccine for Congenital CMV: Rationale and Models.” Plos Pathog 12, no. 2 (February 2016): e1005355. https://doi.org/10.1371/journal.ppat.1005355.Full Text Link to Item
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Martinez, David R., Sallie R. Permar, and Genevieve G. Fouda. “Contrasting Adult and Infant Immune Responses to HIV Infection and Vaccination.” Clin Vaccine Immunol 23, no. 2 (February 2016): 84–94. https://doi.org/10.1128/CVI.00565-15.Full Text Link to Item
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Mansour, Robin G., Lisa Stamper, Frederick Jaeger, Erin McGuire, Genevieve Fouda, Joshua Amos, Kimberly Barbas, et al. “The Presence and Anti-HIV-1 Function of Tenascin C in Breast Milk and Genital Fluids.” Plos One 11, no. 5 (2016): e0155261. https://doi.org/10.1371/journal.pone.0155261.Full Text Link to Item
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Kelly, Matthew S., Daniel K. Benjamin, Karen M. Puopolo, Matthew M. Laughon, Reese H. Clark, Sagori Mukhopadhyay, P Brian Smith, and Sallie R. Permar. “Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia.” Jama Pediatr 169, no. 12 (December 2015): e153785. https://doi.org/10.1001/jamapediatrics.2015.3785.Full Text Link to Item
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Lantos, Paul M., Sallie R. Permar, Kate Hoffman, and Geeta K. Swamy. “The Excess Burden of Cytomegalovirus in African American Communities: A Geospatial Analysis.” Open Forum Infect Dis 2, no. 4 (December 2015): ofv180. https://doi.org/10.1093/ofid/ofv180.Full Text Open Access Copy Link to Item
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Bialas, Kristy M., Takayuki Tanaka, Dollnovan Tran, Valerie Varner, Eduardo Cisneros De La Rosa, Flavia Chiuppesi, Felix Wussow, et al. “Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission.” Proc Natl Acad Sci U S A 112, no. 44 (November 3, 2015): 13645–50. https://doi.org/10.1073/pnas.1511526112.Full Text Link to Item
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Wahl, Angela, Caroline Baker, Rae Ann Spagnuolo, Lisa W. Stamper, Genevieve G. Fouda, Sallie R. Permar, Katie Hinde, et al. “Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity.” J Virol 89, no. 21 (November 2015): 10868–78. https://doi.org/10.1128/JVI.01702-15.Full Text Link to Item
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Pollara, Justin, Erin McGuire, Genevieve G. Fouda, Wes Rountree, Josh Eudailey, R Glenn Overman, Kelly E. Seaton, et al. “Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.” J Virol 89, no. 19 (October 2015): 9952–61. https://doi.org/10.1128/JVI.01560-15.Full Text Open Access Copy Link to Item
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Amos, Joshua D., Jonathon E. Himes, Lawrence Armand, Thaddeus C. Gurley, David R. Martinez, Lisa Colvin, Krista Beck, et al. “Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys.” J Virol 89, no. 18 (September 2015): 9485–98. https://doi.org/10.1128/JVI.01564-15.Full Text Link to Item
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Shen, Xiaoying, Ryan Duffy, Robert Howington, Alethea Cope, Shanmugalakshmi Sadagopal, Haesun Park, Ranajit Pal, et al. “Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8643–50. https://doi.org/10.1128/JVI.03635-14.Full Text Link to Item
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Permar, Sallie R., Youyi Fong, Nathan Vandergrift, Genevieve G. Fouda, Peter Gilbert, Robert Parks, Frederick H. Jaeger, et al. “Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission.” J Clin Invest 125, no. 7 (July 1, 2015): 2702–6. https://doi.org/10.1172/JCI81593.Full Text Open Access Copy Link to Item
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Richard, Jonathan, Maxime Veillette, Nathalie Brassard, Shilpa S. Iyer, Michel Roger, Loïc Martin, Marzena Pazgier, et al. “CD4 mimetics sensitize HIV-1-infected cells to ADCC.” Proc Natl Acad Sci U S A 112, no. 20 (May 19, 2015): E2687–94. https://doi.org/10.1073/pnas.1506755112.Full Text Link to Item
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Fouda, Genevieve G., M Anthony Moody, and Sallie R. Permar. “Antibodies for prevention of mother-to-child transmission of HIV-1.” Curr Opin Hiv Aids 10, no. 3 (May 2015): 177–82. https://doi.org/10.1097/COH.0000000000000150.Full Text Link to Item
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Fong, Youyi, Chongzhi Di, and Sallie Permar. “Change point testing in logistic regression models with interaction term.” Stat Med 34, no. 9 (April 30, 2015): 1483–94. https://doi.org/10.1002/sim.6419.Full Text Link to Item
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Fouda, Genevieve G., Coleen K. Cunningham, and Sallie R. Permar. “Infant HIV-1 vaccines: supplementing strategies to reduce maternal-child transmission.” Jama 313, no. 15 (April 21, 2015): 1513–14. https://doi.org/10.1001/jama.2015.1382.Full Text Link to Item
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Wright, Clyde J., and Sallie R. Permar. “Preventing postnatal cytomegalovirus infection in the preterm infant: should it be done, can it be done, and at what cost?” J Pediatr 166, no. 4 (April 2015): 795–98. https://doi.org/10.1016/j.jpeds.2014.12.062.Full Text Link to Item
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Bialas, Kristy M., Geeta K. Swamy, and Sallie R. Permar. “Perinatal cytomegalovirus and varicella zoster virus infections: epidemiology, prevention, and treatment.” Clin Perinatol 42, no. 1 (March 2015): 61–viii. https://doi.org/10.1016/j.clp.2014.10.006.Full Text Link to Item
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Sacha, C. R., N. Vandergrift, T. L. Jeffries, E. McGuire, G. G. Fouda, B. Liebl, D. J. Marshall, et al. “Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women.” Mucosal Immunol 8, no. 2 (March 2015): 316–26. https://doi.org/10.1038/mi.2014.69.Full Text Link to Item
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Fouda, Genevieve G., Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Petronella Muresan, Justin Pollara, Lin Ye Song, et al. “Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses.” J Infect Dis 211, no. 4 (February 15, 2015): 508–17. https://doi.org/10.1093/infdis/jiu444.Full Text Link to Item
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Bialas, K. M., G. K. Swamy, and S. R. Permar. “Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment.” Neoreviews 16, no. 4 (January 1, 2015): e231–35. https://doi.org/10.1542/neo.16-4-e231.Full Text
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Smith, Shannon D., Joshua D. Amos, Krista N. Beck, Lisa M. Colvin, Kelly S. Franke, Brooke E. Liebl, and Sallie R. Permar. “Refinement of a protocol for the induction of lactation in nonpregnant nonhuman primates by using exogenous hormone treatment.” J Am Assoc Lab Anim Sci 53, no. 6 (November 2014): 700–707.Link to Item
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Chahroudi, Ann, Emily Cartwright, Diane G. Carnathan, S Thera Lee, Benton Lawson, Paul M. Carnathan, Tayebeh Hashempoor, et al. “TARGET CELL AVAILABILITY, RATHER THAN BREAST MILK SPECIFIC FACTORS, DICTATES MOTHER-TO-INFANT TRANSMISSION OF SIV.” Journal of Medical Primatology 43, no. 5 (October 1, 2014): 385–385.Link to Item
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Kaur, Amitinder, Peter Barry, Kristy Bialas, Dollnovan Tran, Valerie Varner, Erika Kunz, Josh Amos, et al. “SUCCESSFUL DEVELOPMENT OF A NONHUMAN PRIMATE MODEL OF CONGENITAL CYTOMEGALOVIRUS TRANSMISSION.” Journal of Medical Primatology 43, no. 5 (October 1, 2014): 426–426.Link to Item
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Dennison, S Moses, Kara M. Anasti, Frederick H. Jaeger, Shelley M. Stewart, Justin Pollara, Pinghuang Liu, Erika L. Kunz, et al. “Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.” J Virol 88, no. 16 (August 2014): 9406–17. https://doi.org/10.1128/JVI.01031-14.Full Text Link to Item
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Fouda, Genevieve G., and Sallie R. Permar. “Immune-based interventions to prevent postnatal HIV-1 transmission.” Trends Microbiol 22, no. 8 (August 2014): 425–27. https://doi.org/10.1016/j.tim.2014.04.009.Full Text Link to Item
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Chahroudi, A., S. Permar, and I. Pandrea. “SIV Transmission in Natural Hosts,” July 10, 2014, 257–68. https://doi.org/10.1016/B978-0-12-404734-1.00013-9.Full Text
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Madani, Navid, Amy M. Princiotto, Arne Schön, Judith LaLonde, Yu Feng, Ernesto Freire, Jongwoo Park, et al. “CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.” J Virol 88, no. 12 (June 2014): 6542–55. https://doi.org/10.1128/JVI.00540-14.Full Text Link to Item
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Permar, Sallie R., and Herman F. Staats. “Which comes first: the antigen or the adjuvant?” J Clin Invest 124, no. 6 (June 2014): 2364–65. https://doi.org/10.1172/JCI76263.Full Text Link to Item
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Chahroudi, Ann, Emily Cartwright, S Thera Lee, Maud Mavigner, Diane G. Carnathan, Benton Lawson, Paul M. Carnathan, et al. “Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.” Plos Pathog 10, no. 3 (March 2014): e1003958. https://doi.org/10.1371/journal.ppat.1003958.Full Text Link to Item
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Meyer, Sarah A., Daniel J. Westreich, Emily Patel, Elizabeth P. Ehlinger, Linda Kalilani, Rachel V. Lovingood, Thomas N. Denny, Geeta K. Swamy, and Sallie R. Permar. “Postnatal cytomegalovirus exposure in infants of antiretroviral-treated and untreated HIV-infected mothers.” Infect Dis Obstet Gynecol 2014 (2014): 989721. https://doi.org/10.1155/2014/989721.Full Text Open Access Copy Link to Item
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Fouda, Genevieve G., Frederick H. Jaeger, Joshua D. Amos, Carrie Ho, Erika L. Kunz, Kara Anasti, Lisa W. Stamper, et al. “Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.” Proc Natl Acad Sci U S A 110, no. 45 (November 5, 2013): 18220–25. https://doi.org/10.1073/pnas.1307336110.Full Text Open Access Copy Link to Item
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Amos, Joshua D., Andrew B. Wilks, Genevieve G. Fouda, Shannon D. Smith, Lisa Colvin, Tatenda Mahlokozera, Carrie Ho, et al. “Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys.” J Virol 87, no. 20 (October 2013): 11121–34. https://doi.org/10.1128/JVI.01887-13.Full Text Open Access Copy Link to Item
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Ho, Carrie, Steven Wu, Joshua D. Amos, Lisa Colvin, Shannon D. Smith, Andrew B. Wilks, C Todd Demarco, et al. “Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys.” J Virol 87, no. 20 (October 2013): 11292–99. https://doi.org/10.1128/JVI.01643-13.Full Text Open Access Copy Link to Item
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Permar, Sallie R., Maria G. Salazar, Feng Gao, Fangping Cai, Gerald H. Learn, Linda Kalilani, Beatrice H. Hahn, George M. Shaw, and Jesus F. Salazar-Gonzalez. “Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis.” Retrovirology 10 (August 14, 2013): 88. https://doi.org/10.1186/1742-4690-10-88.Full Text Link to Item
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Fouda, Genevieve G. A., Joshua D. Amos, Andrew B. Wilks, Justin Pollara, Caroline A. Ray, Anjali Chand, Erika L. Kunz, et al. “Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.” J Virol 87, no. 12 (June 2013): 6986–99. https://doi.org/10.1128/JVI.00528-13.Full Text Link to Item
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Russell, Elizabeth S., Suany Ojeda, Genevieve G. Fouda, Steven R. Meshnick, David Montefiori, Sallie R. Permar, and Ronald Swanstrom. “Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes.” Aids Res Hum Retroviruses 29, no. 3 (March 2013): 511–15. https://doi.org/10.1089/AID.2012.0197.Full Text Link to Item
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Fouda, Genevieve G., Tatenda Mahlokozera, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Gerald Learn, Surender B. Kumar, S Moses Dennison, et al. “Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants.” Retrovirology 10 (January 10, 2013): 3. https://doi.org/10.1186/1742-4690-10-3.Full Text Open Access Copy Link to Item
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Handley, Scott A., Larissa B. Thackray, Guoyan Zhao, Rachel Presti, Andrew D. Miller, Lindsay Droit, Peter Abbink, et al. “Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome.” Cell 151, no. 2 (October 12, 2012): 253–66. https://doi.org/10.1016/j.cell.2012.09.024.Full Text Link to Item
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Schmitz, Joern E., Zhong-Min Ma, Emily A. Hagan, Andrew B. Wilks, Kathryn L. Furr, Caitlyn H. Linde, Roland C. Zahn, Jason M. Brenchley, Christopher J. Miller, and Sallie R. Permar. “Memory CD4(+) T lymphocytes in the gastrointestinal tract are a major source of cell-associated simian immunodeficiency virus in chronic nonpathogenic infection of African green monkeys.” J Virol 86, no. 20 (October 2012): 11380–85. https://doi.org/10.1128/JVI.01556-12.Full Text Link to Item
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Fouda, G., J. Amos, A. B. Wilks, A. Chand, D. Montefiori, B. Haynes, N. Letvin, D. Pickup, H. Liao, and S. R. Permar. “Vaccine-elicited systemic and mucosal humoral responses of lactating rhesus monkeys vaccinated with the transmitted/founder HIV Envelope 1086C.” Retrovirology 9, no. Suppl 2 (2012): O20–O20. https://doi.org/10.1186/1742-4690-9-s2-o20.Full Text
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Friedman, James, S Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, et al. “Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.” Plos One 7, no. 5 (2012): e37648. https://doi.org/10.1371/journal.pone.0037648.Full Text Open Access Copy Link to Item
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Parrish, Nicholas F., Craig B. Wilen, Lauren B. Banks, Shilpa S. Iyer, Jennifer M. Pfaff, Jesus F. Salazar-Gonzalez, Maria G. Salazar, et al. “Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.” Plos Pathog 8, no. 5 (2012): e1002686. https://doi.org/10.1371/journal.ppat.1002686.Full Text Link to Item
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Ehlinger, Elizabeth P., Emily M. Webster, Helen H. Kang, Aislyn Cangialose, Adam C. Simmons, Kimberly H. Barbas, Sandra K. Burchett, Mary L. Gregory, Karen M. Puopolo, and Sallie R. Permar. “Maternal cytomegalovirus-specific immune responses and symptomatic postnatal cytomegalovirus transmission in very low-birth-weight preterm infants.” J Infect Dis 204, no. 11 (December 1, 2011): 1672–82. https://doi.org/10.1093/infdis/jir632.Full Text Link to Item
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Fouda, Genevieve G., Nicole L. Yates, Justin Pollara, Xiaoying Shen, Glenn R. Overman, Tatenda Mahlokozera, Andrew B. Wilks, et al. “HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.” J Virol 85, no. 18 (September 2011): 9555–67. https://doi.org/10.1128/JVI.05174-11.Full Text Open Access Copy Link to Item
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Wilks, Andrew B., James R. Perry, Elizabeth P. Ehlinger, Roland C. Zahn, Robert White, Marie-Claire Gauduin, Angela Carville, Michael S. Seaman, Joern E. Schmitz, and Sallie R. Permar. “High cell-free virus load and robust autologous humoral immune responses in breast milk of simian immunodeficiency virus-infected african green monkeys.” J Virol 85, no. 18 (September 2011): 9517–26. https://doi.org/10.1128/JVI.00796-11.Full Text Link to Item
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Sun, Yue, Mohammed Asmal, Sophie Lane, Sallie R. Permar, Stephen D. Schmidt, John R. Mascola, and Norman L. Letvin. “Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys.” J Virol 85, no. 14 (July 2011): 6906–12. https://doi.org/10.1128/JVI.00326-11.Full Text Link to Item
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Salazar-Gonzalez, Jesus F., Maria G. Salazar, Gerald H. Learn, Genevieve G. Fouda, Helen H. Kang, Tatenda Mahlokozera, Andrew B. Wilks, et al. “Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing.” J Virol 85, no. 6 (March 2011): 2751–63. https://doi.org/10.1128/JVI.02316-10.Full Text Open Access Copy Link to Item
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Mahlokozera, Tatenda, Helen H. Kang, Nilu Goonetilleke, Andrea R. Stacey, Rachel V. Lovingood, Thomas N. Denny, Linda Kalilani, et al. “The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk.” Plos One 6, no. 8 (2011): e23735. https://doi.org/10.1371/journal.pone.0023735.Full Text Open Access Copy Link to Item
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Wilks, Andrew B., Elizabeth C. Christian, Michael S. Seaman, Piya Sircar, Angela Carville, Carmen E. Gomez, Mariano Esteban, et al. “Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys.” J Immunol 185, no. 11 (December 1, 2010): 7097–7106. https://doi.org/10.4049/jimmunol.1002751.Full Text Link to Item
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Permar, Sallie R., Andrew B. Wilks, Elizabeth P. Ehlinger, Helen H. Kang, Tatenda Mahlokozera, Rory T. Coffey, Angela Carville, Norman L. Letvin, and Michael S. Seaman. “Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys.” J Virol 84, no. 16 (August 2010): 8209–18. https://doi.org/10.1128/JVI.00656-10.Full Text Link to Item
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Permar, Sallie R., Helen H. Kang, Andrew B. Wilks, Linh V. Mach, Angela Carville, Keith G. Mansfield, Gerald H. Learn, Beatrice H. Hahn, and Norman L. Letvin. “Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys.” Retrovirology 7 (February 1, 2010): 7. https://doi.org/10.1186/1742-4690-7-7.Full Text Link to Item
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Permar, Sallie R., Helen H. Kang, Andrew B. Wilks, Linh V. Mach, Angela Carville, Keith G. Mansfield, Gerald H. Learn, Beatrice H. Hahn, and Norman L. Letvin. “Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys.” Retrovirology 7 (February 1, 2010). https://doi.org/10.1186/1742-4690-7-7.Full Text Link to Item
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Permar, Sallie R., Helen H. Kang, Angela Carville, Andrew B. Wilks, Keith G. Mansfield, Srinivas S. Rao, and Norman L. Letvin. “Preservation of memory CD4(+) T lymphocytes in breast milk of lactating rhesus monkeys during acute simian immunodeficiency virus infection.” J Infect Dis 201, no. 2 (January 15, 2010): 302–10. https://doi.org/10.1086/649229.Full Text Link to Item
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Permar, Sallie R., Helen H. Kang, Angela Carville, Keith G. Mansfield, Rebecca S. Gelman, Srinivas S. Rao, James B. Whitney, and Norman L. Letvin. “Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys.” J Immunol 181, no. 5 (September 1, 2008): 3643–50. https://doi.org/10.4049/jimmunol.181.5.3643.Full Text Link to Item
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Permar, Sallie R., Srinivas S. Rao, Yue Sun, Saran Bao, Adam P. Buzby, Helen H. Kang, and Norman L. Letvin. “Clinical measles after measles virus challenge in simian immunodeficiency virus-infected measles virus-vaccinated rhesus monkeys.” J Infect Dis 196, no. 12 (December 15, 2007): 1784–93. https://doi.org/10.1086/522967.Full Text Link to Item
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Sun, Yue, Sallie R. Permar, Adam P. Buzby, and Norman L. Letvin. “Memory CD4+ T-lymphocyte loss and dysfunction during primary simian immunodeficiency virus infection.” J Virol 81, no. 15 (August 2007): 8009–15. https://doi.org/10.1128/JVI.00482-07.Full Text Link to Item
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Permar, Sallie R., Diane E. Griffin, and Norman L. Letvin. “Immune containment and consequences of measles virus infection in healthy and immunocompromised individuals.” Clin Vaccine Immunol 13, no. 4 (April 2006): 437–43. https://doi.org/10.1128/CVI.13.4.437-443.2006.Full Text Link to Item
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Permar, Sallie R., Sherry A. Klumpp, Keith G. Mansfield, Angela A. L. Carville, Darci A. Gorgone, Michelle A. Lifton, Jörn E. Schmitz, et al. “Limited contribution of humoral immunity to the clearance of measles viremia in rhesus monkeys.” J Infect Dis 190, no. 5 (September 1, 2004): 998–1005. https://doi.org/10.1086/422846.Full Text Link to Item
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Permar, Sallie R., William J. Moss, Judith J. Ryon, Daniel C. Douek, Mwaka Monze, and Diane E. Griffin. “Increased thymic output during acute measles virus infection.” J Virol 77, no. 14 (July 2003): 7872–79. https://doi.org/10.1128/jvi.77.14.7872-7879.2003.Full Text Link to Item
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Permar, Sallie R., Sherry A. Klumpp, Keith G. Mansfield, Woong-Ki Kim, Darci A. Gorgone, Michelle A. Lifton, Kenneth C. Williams, et al. “Role of CD8(+) lymphocytes in control and clearance of measles virus infection of rhesus monkeys.” J Virol 77, no. 7 (April 2003): 4396–4400. https://doi.org/10.1128/jvi.77.7.4396-4400.2003.Full Text Link to Item
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Zhang, Ying, Sallie Permar, and Zhonghe Sun. “Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide.” J Med Microbiol 51, no. 1 (January 2002): 42–49. https://doi.org/10.1099/0022-1317-51-1-42.Full Text Link to Item
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Permar, S. R., W. J. Moss, J. J. Ryon, M. Monze, F. Cutts, T. C. Quinn, and D. E. Griffin. “Prolonged measles virus shedding in human immunodeficiency virus-infected children, detected by reverse transcriptase-polymerase chain reaction.” J Infect Dis 183, no. 4 (February 15, 2001): 532–38. https://doi.org/10.1086/318533.Full Text Link to Item
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Polack, F. P., S. H. Lee, S. Permar, E. Manyara, H. G. Nousari, Y. Jeng, F. Mustafa, et al. “Successful DNA immunization against measles: neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles.” Nat Med 6, no. 7 (July 2000): 776–81. https://doi.org/10.1038/77506.Full Text Link to Item
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Polack, F. P., S. H. Lee, S. Permar, E. Manyara, H. G. Nousari, Y. Jeng, F. Mustafa, et al. “Erratum: Successful DNA immunization against measles: Neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles (Nature Medicine (2000) 6 (776-781)).” Nature Medicine 6, no. 9 (January 1, 2000): 1062. https://doi.org/10.1038/79586.Full Text
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Cromartie, J. D., S. M. Mercer, S. R. Permar, and A. M. Campbell. “Development of the sarcoplasmic reticulum as a calcium pool in early embryonic chicken hearts.” Molecular Biology of the Cell 7 (December 1, 1996): 775–775.Link to Item
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Book Sections
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Martinez, D. R., J. Mangold, and S. R. Permar. “Maternal vaccination for protection against maternal and infant bacterial and viral pathogens.” In Mucosal Vaccines: Innovation for Preventing Infectious Diseases, 735–49, 2019. https://doi.org/10.1016/B978-0-12-811924-2.00044-4.Full Text
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Conference Papers
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Nelson, A. N., M. Dennis, C. C. LaBranche, J. Eudailey, D. C. Montefiori, R. W. Sanders, J. P. Moore, et al. “HIV envelope BG505 SOSIP immunization induces autologous virus and CD4 binding site-specific B cell lineage antibody precursor responses in infant rhesus macaques.” In Journal of the International Aids Society, 23:168–168, 2020.Link to Item
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Dudley, Dawn, Christina M. Newman, Emma L. Mohr, Matthew T. Aliota, Sydney M. Nguyen, Kathleen M. Antony, Sarah Kohn, et al. “Nonhuman primate models for Zika virus infection.” In Journal of Medical Primatology, 47:326–27. WILEY, 2018.Link to Item
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Hompe, Eliza D., Amit Kumar, Elena E. Giorgi, Erin McGuire, Genevieve G. Fouda, Feng Gao, and Sallie R. Permar. “Induction of Neutralizing Antibodies Against Autologous Viruses in HIV-1 Infected Pregnant Women Immunized With a gp120/160 Vaccine.” In Aids Research and Human Retroviruses, 34:393–393. MARY ANN LIEBERT, INC, 2018.Link to Item
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Martinez, David R., David Martinez, Riley J. Mangan, Elena Georgi, Juilin Chen, Michael Mengual, Jesse Mangold, et al. “Characterizing Env-specific Monoclonal Antibodies Isolated From US and Malawian HIV-infected Non-transmitting and Transmitting Women.” In Aids Research and Human Retroviruses, 34:390–390. MARY ANN LIEBERT, INC, 2018.Link to Item
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Martinez, David R., Youyi Fong, Grace Li, Erin A. Harrell, Madeleine Jennewein, Joshua A. Weiner, Galit Alter, et al. “Determinants of Transplacental Transfer of Protective Maternal IgG in HIV-infected Women.” In Aids Research and Human Retroviruses, 34:339–339. MARY ANN LIEBERT, INC, 2018.Link to Item
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Nelson, Ashley N., Ria Goswami, Maria Dennis, Riley J. Mangan, George M. Shaw, Katharine J. Bar, Kristina De Paris, Koen K. A. Van Rompay, and Sallie R. Permar. “Development of Neutralizing Antibody Responses in SHIV CH505-infected Adult and Infant Rhesus Macaques.” In Aids Research and Human Retroviruses, 34:250–250. MARY ANN LIEBERT, INC, 2018.Link to Item
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Pollara, Justin, Dorothy I. Jones, Tori Huffman, Maria Dennis, Grace Li, Derrick Goodman, R Whitney Edwards, et al. “Bridging Vaccine-induced Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.Link to Item
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Mohr, Emma L., Dawn M. Dudley, Matthew T. Aliota, Andrea Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, et al. “DEVELOPMENT OF A NONHUMAN PRIMATE MODEL OF ZIKA VIRUS INFECTION IN PREGNANT AND NON-PREGNANT RHESUS MACAQUES.” In American Journal of Tropical Medicine and Hygiene, 95:570–570. AMER SOC TROP MED & HYGIENE, 2017.Link to Item
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Goswami, Ria, Jonathon E. Himes, Thomas L. Jeffries, Riley Mangan, Joshua Eudailey, Holly Jakubowski, Quang N. Nguyen, Pyone Aye, and Sallie R. Permar. “Effects of breast milk-derived non-broadly neutralizing antibodies on oral SHIV infection in infant rhesus monkeys.” In Journal of Medical Primatology, 46:189–189. WILEY, 2017.Link to Item
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Kaur, Amitinder, Cody Nelson, Dollnovan Tran, Kristy M. Bialas, Robert Blair, Margaret Gilbert, Peter Barry, and Sallie R. Permar. “Pre-inoculation infusion with hyperimmune globulin protects against vertical transmission in the rhesus macaque model of congenital CMV infection.” In Journal of Medical Primatology, 46:183–183. WILEY, 2017.Link to Item
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Martinez, David R., Erin McGuire, Sallie R. Permar, and Genevieve G. Fouda. “Variable IgG Transplacental Transfer in the Setting of Maternal HIV Infection.” In Aids Research and Human Retroviruses, 32:92–92. MARY ANN LIEBERT, INC, 2016.Link to Item
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Fouda, G. G., C. K. Cunningham, E. J. McFarland, W. Borkowsky, P. Muresan, B. E. Liebl, H. Liao, et al. “HIV-1 gp120 Vaccination Elicits a Robust and Durable Anti-V1/V2 IgG Response and Yet No HIV-1 Env-Specific IgA Response in HIV-Exposed Infants.” In Aids Research and Human Retroviruses, 29:A13–14, 2013.Link to Item
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Kunz, E., G. Fouda, C. Ho, J. Amos, L. Colvin, D. Montefiori, A. Martelli, et al. “Combined Mucosal and Systemic C.1086 Envelope Immunization of Lactating Monkeys Induces Potent IgA and Functional IgG Antibody Responses in Milk.” In Aids Research and Human Retroviruses, 29:A180–A180. MARY ANN LIEBERT, INC, 2013.Link to Item
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Sacha, C. R., N. Vandergrift, D. J. Marshall, T. C. Gurley, L. Stiegel, J. F. Whitesides, J. Friedman, et al. “Distinct VH Gene Usage and HIV Envelope Specificity of Colostrum and Peripheral B Cell Monoclonal Antibodies of HIV-Infected, Lactating African Women.” In Aids Research and Human Retroviruses, 29:A169–70. MARY ANN LIEBERT, INC, 2013.Link to Item
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Amos, J. D., A. B. Wilks, G. G. Fouda, S. D. Smith, G. R. Overman, K. Beck, M. A. Moody, G. D. Tomaras, and S. R. Permar. “Strong SIV gp120-specific IgG/IgA responses in milk of African green monkeys may contribute to the rarity of postnatal transmission in this species.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p198.Full Text
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Salazar-Gonzalez, J. F., M. G. Salazar, G. H. Learn, H. H. Kang, T. Mahlokozera, L. Kalilani, S. R. Meshnick, et al. “Local production of HIV variants in breast milk of chronically HIV-infected, lactating women.” In Aids Research and Human Retroviruses, 26:A148–A148. MARY ANN LIEBERT INC, 2010.Link to Item
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- Teaching & Mentoring
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Recent Courses
- IMMUNOL 493: Research Independent Study 2021
- IMMUNOL 494: Research Independent Study 2021
- IMMUNOL 493: Research Independent Study 2020
- IMMUNOL 494: Research Independent Study 2020
- PATHOL 793: Research Independent Study 2020
- IMMUNOL 493: Research Independent Study 2019
- IMMUNOL 494: Research Independent Study 2019
- PATHOL 793: Research Independent Study 2019
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