Samed Delic

Preprint · March 30, 2026 Chloroplast biogenesis depends on both protein import and organelle division, yet how their coordination emerged during evolution remains unclear. Here, we show that the single septin SEP1 links these pathways in the green alga Chlamydomonas reinhardtii. S ... Full text Link to item Cite

The evolutionary origins and ancestral features of septins.

Journal article Frontiers in cell and developmental biology · January 2024 Septins are a family of membrane-associated cytoskeletal guanine-nucleotide binding proteins that play crucial roles in various cellular processes, such as cell division, phagocytosis, and organelle fission. Despite their importance, the evolutionary origi ... Full text Cite

Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity.

Journal article eLife · November 2019 Alexander disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, but the mechanism linking differe ... Full text Open Access Cite

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