Gregory P. Samsa

Journal article Headache · October 2008 Featured Publication CONTEXT: Headache is a common, disabling disorder that is frequently not well managed in general clinical practice. OBJECTIVE: To determine if patients cared for in a coordinated headache management program would achieve reduced headache disability compare ... Full text Link to item Cite

Facilitated process improvement: an approach to the seamless linkage between evidence and practice in CKD.

Journal article Am J Kidney Dis · March 2006 Featured Publication BACKGROUND: Two common strategies for guideline implementation are preformed practice improvement tools, such as flowcharts, and process reengineering by total quality management (TQM) teams. Prespecified tools fail to accommodate local circumstances, TQM ... Full text Link to item Cite

Which approach to anticoagulation management is best? Illustration of an interactive mathematical model to support informed decision making.

Journal article J Thromb Thrombolysis · October 2002 Featured Publication BACKGROUND: Among patients with atrial fibrillation or mechanical heart valves, determining the best approach to oral anticoagulation largely depends on comparing the costs of anticoagulation management with the costs of events (thromboembolism and bleedin ... Full text Link to item Cite

Have randomized controlled trials of neuroprotective drugs been underpowered? An illustration of three statistical principles.

Journal article Stroke · March 2001 Featured Publication BACKGROUND AND PURPOSE: The results of phase III trials of neuroprotective drugs for acute ischemic stroke have been disappointing. We examine the question of whether these trials may have been underpowered. METHODS: Computer simulations were based on the ... Full text Link to item Cite

Relationship between test frequency and outcomes of anticoagulation: a literature review and commentary with implications for the design of randomized trials of patient self-management.

Journal article J Thromb Thrombolysis · April 2000 Featured Publication BACKGROUND: Patient self-management (PSM) of anticoagulation, which is primarily based upon the premise that more frequent testing will lead to tighter anticoagulation control and thus to improved clinical outcomes, is a promising model of care. The goals ... Full text Link to item Cite