Scholars@Duke
Samuel David Stanley

Samuel David Stanley

Assistant Professor of Orthopaedic Surgery
Orthopaedic Surgery
samuel.stanley@duke.edu
Box 2887, Durham, NC 27710
4709 Creekstone Drive, Suite 200, Durham, NC 27703

Scholarly Works - Journal articles

Lymphokine-activated killer (LAK) cell anti-HIV-1 ADCC reactivity: a potential strategy for reduction of virus-infected cellular reservoirs.

Journal article J Surg Res · October 1998 Lymphocytes from HIV-1-seropositive and -seronegative individuals were examined to determine whether HIV-1 infection interfered with the ability to generate a lymphokine-activated killer (LAK) cell response. Following a 3-day ex vivo incubation in the pres ... Full text Link to item Cite

Sexual function and erection capability among young men with spina bifida.

Journal article Dev Med Child Neurol · September 1996 In a study of sexual function and erection capability, 15 young men with spina bifida were interviewed, underwent physical examination, and completed two consecutive night recordings of penile tumescence and rigidity with the Rigi-Scan (Dacomed Inc.). Elev ... Full text Link to item Cite

Investigation of a synthetic peptide as immunogen for a variant epidermal growth factor receptor associated with gliomas.

Journal article J Neuroimmunol · July 1993 We have previously demonstrated antibody production to a glioma-associated variant form of the human epidermal growth factor receptor in rabbits that had received a synthetic peptide mimicking the unique primary structure of the variant protein as immunoge ... Full text Link to item Cite

The effect of AZT on in vitro lymphokine-activated killer (LAK) activity in human immunodeficiency virus type-1 (HIV-1) infected individuals.

Journal article Cell Immunol · August 1991 Human immunodeficiency virus type-1 (HIV-1)-infected individuals exhibit functional impairment in various forms of cell-mediated cytotoxicities (CMC) at all stages of disease. The purpose of this study was to determine (i) if peripheral blood mononuclear c ... Full text Link to item Cite

Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies.

Journal article J Immunol · November 15, 1990 In an effort to determine the functional activity of anti-HIV-1 human mAb and to define the epitopes against which they are directed, supernatants from 10 EBV-transformed lymphoblastoid cell lines producing mAb to HIV were tested. Five clones producing mAb ... Link to item Cite

Alterations in antibody-dependent cellular cytotoxicity during the course of HIV-1 infection. Humoral and cellular defects.

Journal article J Immunol · May 1, 1990 HIV-1-specific cell-mediated cytotoxicity (CMC) is a form of antibody-dependent cellular cytotoxicity (ADCC) in which HIV-1-specific antibodies arm NK cells directly to become cytotoxic for targets bearing HIV-1 antigenic determinants. This non-MHC-restric ... Link to item Cite

HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection.

Journal article J Immunol · May 1, 1989 The magnitude of immunologic defects observed in HIV-1-infected individuals before the development of overt AIDS is disproportionately high in comparison to the levels of infectious virus in these patients--suggesting that factors other than direct virus-i ... Link to item Cite

GP120 specific cellular cytotoxicity in HIV-1 seropositive individuals. Evidence for circulating CD16+ effector cells armed in vivo with cytophilic antibody.

Journal article J Immunol · February 15, 1989 Fresh circulating PBMC from HIV-1 seropositive individuals have been found to mediate specific, non-MHC restricted lysis of targets expressing the major envelope glycoprotein of HIV-1, gp120, in 6-h 51Cr release assays. This gp120 specific cell-mediated cy ... Link to item Cite