Scholars@Duke
Sargam Kapoor

Sargam Kapoor

Assistant Professor of Medicine
Medicine, Hematology

Scholarly Works

Anticoagulation in malignancy: the patient who bleeds and clots simultaneously.

Journal article Hematology Am Soc Hematol Educ Program · December 5, 2025 Patients with active malignancy frequently require anticoagulation for a variety of indications, including thrombosis, atrial fibrillation, or mechanical heart valves. Cancer-associated thrombosis is associated with significant morbidity and mortality and ... Full text Link to item Cite

Miscalibration of venous thromboembolic risk assessment models across race and ethnicity in medical patients: A cross-model analysis, correction strategy and potential mediators

Conference Blood · November 3, 2025 AbstractBackground: Hospital-associated venous thromboembolism (VTE) affects 350,000 US patients annually and is the leading cause of preve ... Full text Cite

Cytoreductive therapy reduces recurrent thrombosis in patients with myeloproliferative neoplasm-associated splanchnic vein thrombosis: A global abdominal/splanchnic thrombosis retrospective observational study (GASTRO-MPN) study of 757 patients

Conference Blood · November 3, 2025 AbstractBackground Patients with myeloproliferative neoplasms (MPNs) are at risk of splanchnic vein thrombosis (SVT). Prior studies failed ... Full text Cite

Incidence of venous thromboembolism in transgender individuals on estrogen-based gender-affirming hormone therapy

Conference Blood · November 3, 2025 AbstractBackground:Historically, the use of estrogen-based gender-affirming hormone therapy (E-GAHT) ... Full text Cite

The Caprini Score in Black and Latino Patients: A Proposed Race- and Ethnicity-Adjusted Model for Perioperative Venous Thromboembolism Risk Assessment

Conference Blood · November 5, 2024 Background: Perioperative venous thromboembolism (VTE) affects up to 50K US pts/yr, causing morbidity and mortality. The Caprini risk assessment model (RAM; 2005), a validated scoring sys ... Full text Cite

An epidemiologic study comparing cancer- and noncancer-associated venous thromboembolism in a racially diverse Southeastern United States county.

Journal article Res Pract Thromb Haemost · May 2024 BACKGROUND: Cancer-associated venous thromboembolism (CA-VTE) represents a major cause of morbidity and mortality in patients with cancer. Despite poor outcomes, there is an ongoing knowledge gap in epidemiologic data related to this association. OBJECTIVE ... Full text Link to item Cite

Surprise diagnosis of acquired von Willebrand syndrome in a patient previously thought to have type III von Willebrand disease: evaluation and periprocedural management.

Journal article BMJ Case Rep · December 6, 2023 Acquired von Willebrand syndrome (AVWS) is a rare disorder that is characterised by an acquired deficiency of von Willebrand factor. AVWS was suspected in a patient with type III von Willebrand disease (VWD) who did not respond to factor replacement therap ... Full text Open Access Link to item Cite

Thrombotic microangiopathies: An illustrated review

Journal article Research and Practice in Thrombosis and Haemostasis · March 1, 2022 The thrombotic microangiopathies (TMAs) are a heterogenous group of disorders with distinct pathophysiologies that cause occlusive microvascular or macrovascular thrombosis, and are characterized by microangiopathic hemolytic anemia, thrombocytopenia, and/ ... Full text Cite

The hypercoagulable state in COVID-19: Incidence, pathophysiology, and management.

Journal article Thromb Res · October 2020 The 2019 coronavirus disease (COVID-19) presents with a large variety of clinical manifestations ranging from asymptomatic carrier state to severe respiratory distress, multiple organ dysfunction and death. While it was initially considered primarily a res ... Full text Link to item Cite

Priapism, hemoglobin desaturation, and red blood cell adhesion in men with sickle cell anemia.

Journal article Blood Cells Mol Dis · November 2019 Priapism is a serious, but episodic, complication of sickle cell disease (SCD). We had previously reported that subjects with SCD had variable red blood cell (RBC) adhesion to the immobilized sub-endothelial protein laminin (LN). We examined adhesion to LN ... Full text Link to item Cite

Contribution of platelets, the coagulation and fibrinolytic systems to cutaneous wound healing.

Journal article Thromb Res · July 2019 Wound healing is a complex process that consists of multiple phases, each of which are indispensable for adequate repair. Timely initiation and resolution of each of these phases namely, hemostasis, inflammation, proliferation and tissue remodeling, is cri ... Full text Link to item Cite

Advances in the Treatment of Sickle Cell Disease.

Journal article Mayo Clin Proc · December 2018 Sickle cell disease (SCD) is a monogenic disorder that afflicts approximately 100,000 Americans and millions of people worldwide. It is characterized by hemolytic anemia, vaso-occlusive crises, relentless end-organ injury, and premature death. Currently, r ... Full text Link to item Cite

The role of neutrophils in thrombosis.

Journal article Thromb Res · October 2018 Despite significant evidence implicating an important role for neutrophils in thrombosis, their impact on the thrombotic process has remained a matter of controversy. Until 2010, platelets, coagulation factors, fibrinogen and monocytes were implicated in t ... Full text Link to item Cite

Thrombosis

Book section · January 1, 2018 Thromboembolism is a leading cause of morbidity and mortality globally. Survival after VTE (venous thromboembolism including deep venous thrombosis and pulmonary embolism) is worse than the expected survival in age- and sex-matched controls [1, 2]. Moreove ... Full text Cite

Unusual Paraneoplastic Presentation of Cholangiocarcinoma

Journal article Case Reports in Medicine · January 1, 2015 Introduction. Cutaneous paraneoplastic syndromes are a heterogeneous group of skin manifestations that occur in relation to many known malignancies. Paraneoplastic occurrence of SCLE has been noted but is not commonly reported. SCLE association with cholan ... Full text Cite