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Laura Eve Schanberg

Professor of Pediatrics
Pediatrics, Rheumatology
Box 3212 Med Ctr, Durham, NC 27710
T0909, Durham, NC 27710

Featured Works


Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature.

Journal article Pediatr Rheumatol Online J · April 23, 2015 Featured Work UNLABELLED: Avascular necrosis (AVN) occurs in several chronic illnesses, including systemic lupus erythematosus (SLE), but can also occur in healthy children. There are multiple theories to explain why and how AVN occurs, but an exact mechanism has yet to ... Full text Open Access Link to item Cite

Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis.

Journal article Arthritis Rheum · June 2012 Featured Work OBJECTIVE: To determine whether aggressive treatment initiated early in the course of rheumatoid factor (RF)-positive or RF-negative polyarticular juvenile idiopathic arthritis (JIA) can induce clinical inactive disease within 6 months. METHODS: Between Ma ... Full text Link to item Cite

Daily sleep quality and mood as predictors of pain in children with juvenile polyarticular arthritis.

Journal article Health Psychol · March 2012 Featured Work OBJECTIVE: Children with arthritis experience frequent pain, but the predictors of daily pain variations are largely unidentified. The goal of this study was to examine sleep quality as a predictor of pain in children with arthritis and to determine whethe ... Full text Link to item Cite

Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus.

Journal article Arthritis Care Res (Hoboken) · March 2012 Featured Work OBJECTIVE: To formulate consensus treatment plans (CTPs) for induction therapy of newly diagnosed proliferative lupus nephritis (LN) in juvenile systemic lupus erythematosus (SLE). METHODS: A structured consensus formation process was employed by the membe ... Full text Link to item Cite

Emotion regulation predicts pain and functioning in children with juvenile idiopathic arthritis: an electronic diary study.

Journal article J Pediatr Psychol · 2012 Featured Work OBJECTIVES: This study utilized e-diaries to evaluate whether components of emotion regulation predict daily pain and function in children with juvenile idiopathic arthritis (JIA). METHODS: 43 children ages 8-17 years and their caregivers provided baseline ... Full text Link to item Cite

Use of atorvastatin in systemic lupus erythematosus in children and adolescents.

Journal article Arthritis Rheum · January 2012 Featured Work OBJECTIVE: Statins reduce atherosclerosis and cardiovascular morbidity in the general population, but their efficacy and safety in children and adolescents with systemic lupus erythematosus (SLE) are unknown. This study was undertaken to determine the 3-ye ... Full text Link to item Cite

A proposed framework to standardize the neurocognitive assessment of patients with pediatric systemic lupus erythematosus.

Journal article Arthritis Care Res (Hoboken) · July 2010 Featured Work OBJECTIVE: To develop and propose a standardized battery of neuropsychological tests for the assessment of cognitive functioning of children and adolescents with pediatric systemic lupus erythematosus (SLE). METHODS: A committee of health care professional ... Full text Link to item Cite

Toward the development of criteria for global flares in juvenile systemic lupus erythematosus.

Journal article Arthritis Care Res (Hoboken) · June 2010 Featured Work OBJECTIVE: To develop a definition of global flare in juvenile systemic lupus erythematosus (SLE) and derive candidate criteria for measuring juvenile SLE flares. METHODS: Pediatric rheumatologists answered 2 Delphi questionnaires to achieve consensus on a ... Full text Link to item Cite

Parent pain responses as predictors of daily activities and mood in children with juvenile idiopathic arthritis: the utility of electronic diaries.

Journal article J Pain Symptom Manage · March 2010 Featured Work The present study used electronic diaries to examine how parent responses to their child's pain predict daily adjustment of children with juvenile idiopathic arthritis (JIA). Nine school-aged children with JIA along with one of their parents completed thri ... Full text Link to item Cite

Premature atherosclerosis in pediatric systemic lupus erythematosus: risk factors for increased carotid intima-media thickness in the atherosclerosis prevention in pediatric lupus erythematosus cohort.

Journal article Arthritis Rheum · May 2009 Featured Work OBJECTIVE: To evaluate risk factors for subclinical atherosclerosis in a population of patients with pediatric systemic lupus erythematosus (SLE). METHODS: In a prospective multicenter study, a cohort of 221 patients underwent baseline measurements of caro ... Full text Link to item Cite

Neurocognitive impairment in children and adolescents with systemic lupus erythematosus.

Journal article Nat Clin Pract Rheumatol · February 2009 Featured Work Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease, in which neuropsychiatric manifestations are a common cause of significant morbidity. The American College of Rheumatology has identified 19 distinct neuropsychiatric syndromes associa ... Full text Link to item Cite

Therapy Insight: cardiovascular disease in pediatric systemic lupus erythematosus.

Journal article Nat Clin Pract Rheumatol · May 2008 Featured Work In 15-20% of cases, systemic lupus erythematosus (SLE) presents before the age of 18 years, and such early-onset SLE seems to be particularly severe. SLE is an independent risk factor for premature atherosclerosis and death in young, premenopausal women wi ... Full text Link to item Cite

Assessment and management of pain syndromes and arthritis pain in children and adolescents.

Journal article Rheum Dis Clin North Am · August 2007 Featured Work Chronic musculoskeletal pain, whether it is idiopathic or disease-related, is common in childhood. Pediatric rheumatologists and other pediatric health care providers must understand the epidemiology of musculoskeletal pain as part of childhood, diagnose p ... Full text Link to item Cite

Management of dyslipidemia in children and adolescents with systemic lupus erythematosus.

Journal article Lupus · 2007 Featured Work Systemic lupus erythematosus (SLE) is an independent risk factor for atherosclerosis, placing children and adolescents with SLE at great risk for developing cardiovascular sequelae, including myocardial infarction, in adulthood. Dyslipidemia and other trad ... Full text Link to item Cite

Treatment of pain in juvenile idiopathic arthritis: a survey of pediatric rheumatologists.

Journal article Arthritis Rheum · February 15, 2006 Featured Work OBJECTIVE: To assess the opinions and current practice of pediatric rheumatologists regarding treatment of chronic pain in children with juvenile idiopathic arthritis (JIA). METHODS: Standardized questionnaires were distributed to pediatric rheumatologists ... Full text Link to item Cite

The management of pediatric systemic lupus erythematosus.

Journal article Nat Clin Pract Rheumatol · December 2005 Featured Work Most children and adolescents with systemic lupus erythematosus (SLE) now survive into adulthood, leading the pediatric rheumatology community to focus on preventing long-term complications of SLE, including atherosclerosis, obesity, and osteoporosis, and ... Full text Link to item Cite

Pain, stiffness, and fatigue in juvenile polyarticular arthritis: contemporaneous stressful events and mood as predictors.

Journal article Arthritis Rheum · April 2005 Featured Work OBJECTIVE: To analyze patterns of stress, mood, disease symptoms, and activity reduction in children with polyarticular arthritis, using a prospective daily diary method. METHODS: For a 2-month period, 51 children with polyarticular arthritis (mean age 12. ... Full text Link to item Cite

Dyslipoproteinemia and premature atherosclerosis in pediatric systemic lupus erythematosus.

Journal article Curr Rheumatol Rep · December 2004 Featured Work While modern treatments for systemic lupus erythematosus (SLE) have resulted in greatly improved long term outcome in children and adults, complications of atherosclerosis have become a major cause of morbidity and mortality. Although children and adolesce ... Full text Link to item Cite

Peer rejection, social behavior, and psychological adjustment in children with juvenile rheumatic disease.

Journal article J Pediatr Psychol · 2004 Featured Work OBJECTIVE: To examine the associations among disease status, social competence, and depressive symptoms in children with juvenile rheumatic disease (JRD) and to test the hypothesis that individual differences in children's social competence account for a s ... Full text Link to item Cite

Widespread pain in children: when is it pathologic?

Journal article Arthritis Rheum · September 2003 Featured Work Full text Link to item Cite

Daily pain and symptoms in children with polyarticular arthritis.

Journal article Arthritis Rheum · May 2003 Featured Work OBJECTIVE: To analyze patterns of daily pain, stiffness, and fatigue related to juvenile arthritis; to examine the relationships of demographics, disease severity, and psychological adjustment to daily disease symptoms; and to examine daily disease symptom ... Full text Link to item Cite

Pain in children with arthritis: a review of the current literature.

Journal article Arthritis Rheum · April 15, 2003 Featured Work Full text Link to item Cite

Brief report: Parental perceptions of child vulnerability in children with chronic illness.

Journal article J Pediatr Psychol · 2003 Featured Work OBJECTIVE: To determine the extent to which parental perceptions of child vulnerability predict school and social adjustment in children with chronic illness. METHODS: Sixty-nine child-parent dyads were recruited from pediatric rheumatology and pulmonary c ... Full text Link to item Cite

Family pain history predicts child health status in children with chronic rheumatic disease.

Journal article Pediatrics · September 2001 Featured Work OBJECTIVES: To examine the relationships of parental and family pain history on the pain experience of children with chronic rheumatic disease. The aims of the study were as follows: 1) to describe the pain history of parents and families of children with ... Full text Link to item Cite

The relationship of daily mood and stressful events to symptoms in juvenile rheumatic disease.

Journal article Arthritis Care Res · February 2000 Featured Work OBJECTIVES: The purpose of this study was 3-fold: 1) to assess the feasibility of a daily diary for use with children with juvenile rheumatic disease (JRD), 2) to describe daily variation in mood, stressful events, and symptoms in children with JRD, and 3) ... Full text Link to item Cite

Social context of pain in children with Juvenile Primary Fibromyalgia Syndrome: parental pain history and family environment.

Journal article Clin J Pain · June 1998 Featured Work OBJECTIVE: The purpose of this study was to describe parental pain history and the family environment as it relates to the functional status of children with Juvenile Primary Fibromyalgia Syndrome (JPFS). DESIGN AND OUTCOME MEASURES: Twenty-nine parents of ... Full text Link to item Cite

Pain coping and the pain experience in children with juvenile chronic arthritis.

Journal article Pain · November 1997 Featured Work This study examined the pain experience and pain coping of children with juvenile chronic arthritis (JCA). The purpose of the study was to describe present pain and the pain coping strategies utilized by children with juvenile chronic arthritis and examine ... Full text Link to item Cite

Pain coping strategies in children with juvenile primary fibromyalgia syndrome: correlation with pain, physical function, and psychological distress.

Journal article Arthritis Care Res · April 1996 Featured Work OBJECTIVES: The purpose of this study was twofold: 1) to describe the coping strategies used by children with juvenile primary fibromyalgia syndrome (JPFS), and 2) to examine how pain coping relates to measures of pain, disability/function, psychological d ... Full text Link to item Cite