Skip to main content

William Schuyler Jones

Professor of Medicine
Medicine, Cardiology
Duke Box 3330, Durham, NC 27710
2400 Pratt Street, 7037, Durham, NC 27705

Overview


I am an interventional cardiologist with a specific focus on the diagnosis and treatment of patients with cardiovascular disease. As a clinician, I see patients in the office and do coronary and peripheral vascular procedures (angiography and interventions) in the Duke Cardiac Catheterization Laboratory. I have served as the Medical Director of the cath lab at Duke since 2016. Alongside my partners in the cath lab, we collaborate with our cardiothoracic surgeons to hold Heart Team meetings each week, and we frequently are asked to address complex cardiovascular issues as a multidisciplinary team.

I also have a broad background in cardiovascular site-based research, multicenter clinical trials, clinical event classification, and observational analyses. I have helped to lead clinical trial efforts at the Duke Clinical Research Institute (DCRI) by designing and conducting studies evaluating new and existing treatments for patients with coronary artery disease and peripheral artery disease. My specific research interests include examining access to care and disparities in care for patients with peripheral artery disease and the design and conduct of pragmatic clinical trials in cardiovascular disease.

Current Appointments & Affiliations


Professor of Medicine · 2024 - Present Medicine, Cardiology, Medicine
Professor in Population Health Sciences · 2024 - Present Population Health Sciences, Basic Science Departments
Member in the Duke Clinical Research Institute · 2013 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Femoropopliteal Endovascular Intervention: A Review of the Current Landscape.

Journal Article Circ Cardiovasc Interv · April 25, 2025 Superficial femoral artery disease poses significant challenges in patients with peripheral artery disease due to its unique anatomic and physiological characteristics. While conservative measures remain the initial approach for chronic, stable symptoms, e ... Full text Link to item Cite

Vascular Access and Management of Complications.

Journal Article Interv Cardiol Clin · April 2025 Vascular access requires a deliberate and thoughtful approach. Optimal femoral access involves understanding anatomic, fluoroscopic, and ultrasound principles. Combining all 3 approaches optimizes femoral access and minimizes complications, with ultrasound ... Full text Link to item Cite

2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Journal Article Circulation · April 1, 2025 Aim: The “2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes” incorporates new evidence since the “2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction” and the corresponding “20 ... Full text Cite
View All Publications

Recent Grants


1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2030

V-Intervention

Clinical TrialPrincipal Investigator · Awarded by Novartis Pharmaceuticals Corporation · 2025 - 2029

Deprescribing Decision-Making using Machine Learning Individualized Treatment Rules to Improve CNS Polypharmacy

ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2029

View All Grants

Education, Training & Certifications


University of Arkansas, Little Rock · 2001 M.D.