Scholars@Duke
Scott Alderman

Scott Alderman

Adjunct Associate in the Department of Medicine
Medicine, Duke Human Vaccine Institute
scott.alderman@duke.edu
Box 103020 Med Ctr, Durham, NC 27710
909 S LaSalle St - GHRB 1001, Durham, NC 27710

Scholarly Works

Validating an Autoclave Cycle for Sterilization of Select Agent-Infected Murine Carcasses

Journal article Applied Biosafety · March 28, 2026 Introduction:Infectious disease research conducted in the Duke Regional Biocontainment Laboratory, a biosafety level-3 facility, often includes work with mice. Infected ca ... Full text Open Access Cite

Strain Agnostic Influenza Virus Propagation in a Serum-Free, Suspension-Adapted MDCK Cell Line.

Journal article Influenza Other Respir Viruses · March 2026 BACKGROUND: The continuing circulation and evolution of seasonal influenza viruses remains a public health and socioeconomic threat on a global scale. Viral surveillance and vaccination of the public have been relied upon to confer and boost immunity in th ... Full text Open Access Link to item Cite

Validating Autoclave Cycles for Carcass Disposal in Animal Biosafety Level 2/3 Containment Laboratories

Journal article Applied Biosafety · September 1, 2019 Introduction: Animal carcasses differ in composition from other types of solid waste, and through prior testing it was determined that cycle parameters applied to general, solid biohazardous waste did not ensure proper sterilization of ferret carcasses. Ob ... Full text Open Access Cite

Managing Research Animal Specimens and Laboratory Safety.

Journal article ILAR J · December 31, 2018 The procedures necessary to perform testing in a veterinary diagnostic laboratory have inherent associated risks to personnel in regard to exposure to infectious agents. In research institutions animals can be experimentally infected, acquire naturally occ ... Full text Link to item Cite

Animal Research Biosafety

Journal article Applied Biosafety · September 1, 2018 The use of laboratory animals as experimental models of disease has been a critical tool for biomedical researchers for decades. Animal studies allow scientists to discover and understand the mechanism of infection and ultimately to develop effective treat ... Full text Cite

Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

Journal article Biosecurity and bioterrorism : biodefense strategy, practice, and science · March 2013 The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainm ... Full text Cite

Validation of an Animal Isolation Imaging Chamber for Use in Animal Biosafety Level-3 Containment.

Journal article Appl Biosaf · 2010 Live imaging of animals infected with pathogenic microbes poses a contamination risk to equipment, personnel and other animals. A Caliper animal isolation chamber designed for the IVIS(®) Spectrum imaging system was tested as a containment device for mice ... Full text Open Access Link to item Cite

Assessment of bioaerosol reduction methods in stem cell transplant units at a University Hospital

Journal article Iaq Conference · December 1, 2004 Severely immunocompromised patients, such as those who have undergone stem cell transplantation, must be housed in a protective environment to reduce the risk of acquiring health care-associated fungal infections. This 11-month study was conducted at Duke ... Open Access Cite