Scott Knowles Pruitt | Scholars@Duke

Scott Knowles Pruitt
Adjunct Associate Professor in the Department of Surgery

Current Appointments & Affiliations

Adjunct Associate Professor in the Department of Surgery, Surgical Oncology, Surgery 2013

Contact Information

Box 3966 Med Ctr, Durham, NC 27710
Rm 239 Hanes House, Durham, NC 27710
scott.pruitt@duke.edu (919) 684-3942

Background
Education, Training, & Certifications
- Ph.D., Duke University 1994
- M.D., Columbia University 1987
Duke Appointment History
- Associate Professor of Surgery, Surgical Oncology, Surgery 2008 - 2013
- Associate Professor of Surgery, Surgery, Clinical Science Departments 2005 - 2008
- Assistant Professor of Surgery, Surgery, Clinical Science Departments 1997 - 2005
- Instructor, Temporary in the Department of Surgery, Surgery, Clinical Science Departments 1997
Research
Selected Grants
- Large Scale Antibody and TCell Epitope Discovery awarded by National Institutes of Health 2004 - 2011
- Novel Strategies to Broaden the Impact of HIFU Therapy in Cancer Management awarded by National Institutes of Health 2008 - 2011
- IPA - Jens Dannull awarded by Veterans Administration Medical Center 2008 - 2010
- Immune Response to Breast Ductal Carcinoma In Situ awarded by National Institutes of Health 1992 - 2000
- Modulation Of Hyperacute Xenograft Rejection awarded by National Institutes of Health 1993 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Wang, H, Heck, K, Pruitt, SK, Wong, TZ, Scheri, RP, Georgiade, GS, Ichite, I, and Hwang, ES. "Impact of delayed lymphoscintigraphy for sentinel lymphnode biopsy for breast cancer." Journal of surgical oncology 111, no. 8 (June 2015): 931-934. Full Text
  - Dannull, J, Tan, C, Farrell, C, Wang, C, Pruitt, S, Nair, SK, and Lee, WT. "Gene Expression Profile of Dendritic Cell-Tumor Cell Hybrids Determined by Microarrays and Its Implications for Cancer Immunotherapy." Journal of immunology research 2015 (January 2015): 789136-. Full Text
  - Phua, KKL, Boczkowski, D, Dannull, J, Pruitt, S, Leong, KW, and Nair, SK. "Whole blood cells loaded with messenger RNA as an anti-tumor vaccine." Adv Healthc Mater 3, no. 6 (June 2014): 837-842. Full Text Link to Item
  - Nair, SK, Tomaras, GD, Sales, AP, Boczkowski, D, Chan, C, Plonk, K, Cai, Y, Dannull, J, Kepler, TB, Pruitt, SK, and Weinhold, KJ. "High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes." Scientific reports 4 (April 23, 2014): 4632-. Full Text
  - Tan, C, Dannull, J, Nair, SK, Ding, E, Tyler, DS, Pruitt, SK, and Lee, WT. "Local secretion of IL-12 augments the therapeutic impact of dendritic cell-tumor cell fusion vaccination." J Surg Res 185, no. 2 (December 2013): 904-911. Full Text Link to Item
  - Tan, C, Reddy, V, Dannull, J, Ding, E, Nair, SK, Tyler, DS, Pruitt, SK, and Lee, WT. "Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model. (Published online)" J Transl Med 11 (June 17, 2013): 148-. Full Text Link to Item
  - Coit, DG, Andtbacka, R, Anker, CJ, Bichakjian, CK, Carson, WE, Daud, A, Dimaio, D, Fleming, MD, Guild, V, Halpern, AC, Hodi, FS, Kelley, MC, Khushalani, NI, Kudchadkar, RR, Lange, JR, Lind, A, Martini, MC, Olszanski, AJ, Pruitt, SK, Ross, MI, Swetter, SM, Tanabe, KK, Thompson, JA, Trisal, V, Urist, MM, McMillian, N, Ho, M, and National Comprehensive Cancer Network (NCCN), . "Melanoma, version 2.2013: featured updates to the NCCN guidelines." Journal of the National Comprehensive Cancer Network : Jnccn 11, no. 4 (April 2013): 395-407. Full Text
  - Lyman, GH, Baker, J, Geradts, J, Horton, J, Kimmick, G, Peppercorn, J, Pruitt, S, Scheri, RP, and Hwang, ES. "Multidisciplinary care of patients with early-stage breast cancer." Surg Oncol Clin N Am 22, no. 2 (April 2013): 299-317. (Review) Full Text Link to Item
  - Shetty, G, Beasley, GM, Sparks, S, Barfield, M, Masoud, M, Mosca, PJ, Pruitt, SK, Salama, AKS, Chan, C, Tyler, DS, and Weinhold, KJ. "Plasma cytokine analysis in patients with advanced extremity melanoma undergoing isolated limb infusion." Ann Surg Oncol 20, no. 4 (April 2013): 1128-1135. Full Text Link to Item
  - Dannull, J, Haley, NR, Archer, G, Nair, S, Boczkowski, D, Harper, M, Rosa, ND, Pickett, N, Mosca, PJ, Burchette, J, Selim, MA, Mitchell, DA, Sampson, J, Tyler, DS, and Pruitt, SK. "Melanoma immunotherapy using mature DCs expressing the constitutive proteasome." Journal of Clinical Investigation 123, no. 7 (2013): 3135-3145. Full Text
  - Salama, AKS, de Rosa, N, Scheri, RP, Pruitt, SK, Herndon, JE, Marcello, J, Tyler, DS, and Abernethy, AP. "Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy." PLoS One 8, no. 3 (2013): e57665-. Full Text Open Access Copy Link to Item
  - Tan, C, Dannull, J, Nair, SK, Ding, E, Tyler, DS, Pruitt, SK, and Lee, WT. "Local secretion of IL-12 augments the therapeutic impact of dendritic celletumor cell fusion vaccination." Journal of Surgical Research 185, no. 2 (January 1, 2013): 904-911. Full Text
  - Salama, AKS, Rosa, ND, Scheri, RP, Herndon, JE, Tyler, DS, Marcello, J, Pruitt, SK, and Abernethy, AP. "The effect of metastatic site and decade of diagnosis on the individual burden of metastatic melanoma: contemporary estimates of average years of life lost." Cancer Invest 30, no. 9 (November 2012): 637-641. Full Text Link to Item
  - Dannull, J, Haley, NR, Archer, G, Nair, S, Rosa, ND, Selim, M, Tyler, DS, Sampson, J, and Pruitt, SK. "Abstract 5373: Altering the composition of the proteasome of melanoma antigen RNA-transfected dendritic cells enhances vaccination-induced anti-melanoma immunity: results of a Phase I trial." Cancer Research 72, no. 8 Supplement (April 15, 2012): 5373-5373. Full Text
  - Tan, C, Reddy, V, Ding, E, Dannull, J, Nair, S, Pruitt, SK, and Lee, WT. "Abstract 4389: Impact of regulatory T cell depletion on dendritic cell-tumor fusion vaccine immunotherapy." Cancer Research 72, no. 8 Supplement (April 15, 2012): 4389-4389. Full Text
  - Dannull, J, Schneider, T, Lee, WT, de Rosa, N, Tyler, DS, and Pruitt, SK. "Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function." Blood 119, no. 13 (March 29, 2012): 3113-3122. Full Text Link to Item
  - Coit, DG, Andtbacka, R, Anker, CJ, Bichakjian, CK, III, WEC, Daud, A, Dilawari, RA, DiMaio, D, Guild, V, Halpern, AC, and al, E. "Melanoma." JNCCN Journal of the National Comprehensive Cancer Network 10, no. 3 (2012): 366-400.
  - Pruitt, SK, Boczkowski, D, de Rosa, N, Haley, NR, Morse, MA, Tyler, DS, Dannull, J, and Nair, S. "Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells." Eur J Immunol 41, no. 12 (December 2011): 3553-3563. Full Text Link to Item
  - Pruitt, SK, Boczkowski, D, de Rosa, N, Haley, NR, Morse, MA, Tyler, DS, Dannull, J, and Nair, S. "Enhancement of Anti-Tumor Immunity Through Local Modulation of CTLA-4 and GITR by Dendritic Cells." Eur J Immunol (September 9, 2011). Full Text Link to Item
  - de Rosa, N, Lyman, GH, Silbermins, D, Valsecchi, ME, Pruitt, SK, Tyler, DM, and Lee, WT. "Sentinel node biopsy for head and neck melanoma: a systematic review." Otolaryngol Head Neck Surg 145, no. 3 (September 2011): 375-382. (Review) Full Text Link to Item
  - Raymond, AK, Beasley, GM, Broadwater, G, Augustine, CK, Padussis, JC, Turley, R, Peterson, B, Seigler, H, Pruitt, SK, and Tyler, DS. "Current trends in regional therapy for melanoma: lessons learned from 225 regional chemotherapy treatments between 1995 and 2010 at a single institution." J Am Coll Surg 213, no. 2 (August 2011): 306-316. Full Text Link to Item
  - Toshimitsu, H, Yoshimoto, Y, Augustine, CK, Padussis, JC, Yoo, JS, Angelica Selim, M, Pruitt, SK, Friedman, HS, Ali-Osman, F, and Tyler, DS. "Inhibition of poly(ADP-ribose) polymerase enhances the effect of chemotherapy in an animal model of regional therapy for the treatment of advanced extremity malignant melanoma." Ann Surg Oncol 17, no. 8 (August 2010): 2247-2254. Full Text Link to Item
  - Augustine, CK, Toshimitsu, H, Jung, S-H, Zipfel, PA, Yoo, JS, Yoshimoto, Y, Selim, MA, Burchette, J, Beasley, GM, McMahon, N, Padussis, J, Pruitt, SK, Ali-Osman, F, and Tyler, DS. "Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy." Mol Cancer Ther 9, no. 7 (July 2010): 2090-2101. Full Text Link to Item
  - Boczkowski, D, Lee, J, Pruitt, S, and Nair, S. "Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy." Cancer Gene Ther 16, no. 12 (December 2009): 900-911. Full Text Link to Item
  - Aldrink, JH, Selim, MA, Diesen, DL, Johnson, J, Pruitt, SK, Tyler, DS, and Seigler, HF. "Pediatric melanoma: a single-institution experience of 150 patients." Journal of Pediatric Surgery 44, no. 8 (August 2009): 1514-1521. Full Text
  - Beasley, GM, Caudle, A, Petersen, RP, McMahon, NS, Padussis, J, Mosca, PJ, Zager, JS, Hochwald, SN, Grobmyer, SR, Delman, KA, Andtbacka, RH, Noyes, RD, Kane, JM, Seigler, H, Pruitt, SK, Ross, MI, and Tyler, DS. "A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US." J Am Coll Surg 208, no. 5 (May 2009): 706-715. Full Text Link to Item
  - Coit, DG, Andtbacka, R, Bichakjian, CK, Dilawari, RA, Dimaio, D, Guild, V, Halpern, AC, Hodi, FS, Kashani-Sabet, M, Lange, JR, Lind, A, Martin, L, Martini, MC, Pruitt, SK, Ross, MI, Sener, SF, Swetter, SM, Tanabe, KK, Thompson, JA, Trisal, V, Urist, MM, Weber, J, Wong, MK, and NCCN Melanoma Panel, . "Melanoma." Journal of the National Comprehensive Cancer Network : Jnccn 7, no. 3 (March 2009): 250-275. Full Text
  - Beasley, GM, Petersen, RP, Yoo, J, McMahon, N, Aloia, T, Petros, W, Sanders, G, Cheng, T-Y, Pruitt, SK, Seigler, H, and Tyler, DS. "Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion." Ann Surg Oncol 15, no. 8 (August 2008): 2195-2205. Full Text Link to Item
  - Dannull, J, Lesher, D-T, Holzknecht, R, Qi, W, Hanna, G, Seigler, H, Tyler, DS, and Pruitt, SK. "Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity." Blood 110, no. 13 (December 15, 2007): 4341-4350. Full Text Link to Item
  - Yoshimoto, Y, Augustine, CK, Yoo, JS, Zipfel, PA, Selim, MA, Pruitt, SK, Friedman, HS, Ali-Osman, F, and Tyler, DS. "Defining regional infusion treatment strategies for extremity melanoma: comparative analysis of melphalan and temozolomide as regional chemotherapeutic agents." Mol Cancer Ther 6, no. 5 (May 2007): 1492-1500. Full Text Link to Item
  - Grubbs, EG, Abdel-Wahab, Z, Tyler, DS, and Pruitt, SK. "Utilizing quantitative polymerase chain reaction to evaluate prostate stem cell antigen as a tumor marker in pancreatic cancer." Annals of Surgical Oncology 13, no. 12 (December 2006): 1645-1654. Full Text
  - Ueno, T, Ko, SH, Grubbs, E, Yoshimoto, Y, Augustine, C, Abdel-Wahab, Z, Cheng, T-Y, Abdel-Wahab, OI, Pruitt, SK, Friedman, HS, and Tyler, DS. "Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine." Mol Cancer Ther 5, no. 3 (March 2006): 732-738. Full Text Link to Item
  - Ko, SH, Ueno, T, Yoshimoto, Y, Yoo, JS, Abdel-Wahab, OI, Abdel-Wahab, Z, Chu, E, Pruitt, SK, Friedman, HS, Dewhirst, MW, and Tyler, DS. "Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 12, no. 1 (January 2006): 289-297. Full Text
  - Abdel-Wahab, Z, Cisco, R, Dannull, J, Ueno, T, Abdel-Wahab, O, Kalady, MF, Onaitis, MW, Tyler, DS, and Pruitt, SK. "Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses." J Surg Res 124, no. 2 (April 2005): 264-273. Full Text Link to Item
  - Ueno, T, Ko, SH, Grubbs, E, Pruitt, SK, Friedman, HS, and Tyler, DS. "Temozolomide is a novel regional infusion agent for the treatment of advanced extremity melanoma." Am J Surg 188, no. 5 (November 2004): 532-537. Full Text Link to Item
  - Abdel-Wahab, OI, Grubbs, E, Viglianti, BL, Cheng, T-Y, Ueno, T, Ko, S, Rabbani, Z, Curtis, S, Pruitt, SK, Dewhirst, MW, and Tyler, DS. "The role of hyperthermia in regional alkylating agent chemotherapy." Clin Cancer Res 10, no. 17 (September 1, 2004): 5919-5929. Full Text Link to Item
  - Grubbs, EG, Abdel-Wahab, O, Cheng, T-Y, Abdel-Wahab, Z, Peterson, B, Pruitt, SK, Colvin, OM, Friedman, HS, and Tyler, DS. "In-transit melanoma: the role of alkylating-agent resistance in regional therapy." J Am Coll Surg 199, no. 3 (September 2004): 419-427. Full Text Link to Item
  - Grubbs, EG, Ueno, T, Abdel-Wahab, O, Cheng, T-Y, Pruitt, SK, Michael Colvin, O, Friedman, HS, and Tyler, DS. "Modulation of resistance to regional chemotherapy in the extremity melanoma model." Surgery 136, no. 2 (August 2004): 210-218. Full Text
  - Cisco, RM, Abdel-Wahab, Z, Dannull, J, Nair, S, Tyler, DS, Gilboa, E, Vieweg, J, Daaka, Y, and Pruitt, SK. "Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4." J Immunol 172, no. 11 (June 1, 2004): 7162-7168. Link to Item
  - Kalady, MF, Onaitis, MW, Emani, S, Abdul-Wahab, Z, Pruitt, SK, and Tyler, DS. "Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific antipancreatic cancer T cells." J Gastrointest Surg 8, no. 2 (February 2004): 175-181. Full Text Link to Item
  - Kalady, MF, Onaitis, MW, Emani, S, Abdel-Wahab, Z, Tyler, DS, and Pruitt, SK. "Sequential delivery of maturation stimuli increases human dendritic cell IL-12 production and enhances tumor antigen-specific immunogenicity." J Surg Res 116, no. 1 (January 2004): 24-31. Link to Item
  - Cheng, T-Y, Grubbs, E, Abdul-Wahab, O, Leu, S-Y, Hung, C-F, Petros, W, Aloia, T, Fedrau, R, Pruitt, S, Colvin, M, Friedman, H, and Tyler, D. "Marked variability of melphalan plasma drug levels during regional hyperthermic isolated limb perfusion." Am J Surg 186, no. 5 (November 2003): 460-467. Link to Item
  - Abdel-Wahab, Z, Kalady, MF, Emani, S, Onaitis, MW, Abdel-Wahab, OI, Cisco, R, Wheless, L, Cheng, T-Y, Tyler, DS, and Pruitt, SK. "Induction of anti-melanoma CTL response using DC transfected with mutated mRNA encoding full-length Melan-A/MART-1 antigen with an A27L amino acid substitution." Cell Immunol 224, no. 2 (August 2003): 86-97. Link to Item
  - Onaitis, MW, Kalady, MF, Emani, S, Abdel-Wahab, Z, Tyler, DS, and Pruitt, SK. "CD40 ligand is essential for generation of specific cytotoxic T cell responses in RNA-pulsed dendritic cell immunotherapy." Surgery 134, no. 2 (August 2003): 300-305. Full Text Link to Item
  - Su, Z, Dannull, J, Heiser, A, Yancey, D, Pruitt, S, Madden, J, Coleman, D, Niedzwiecki, D, Gilboa, E, and Vieweg, J. "Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells." Cancer Research 63, no. 9 (May 2003): 2127-2133.
  - Abdel-Wahab, Z, Kalady, MF, Emani, S, Onaitis, MW, Abdel-Wahab, OI, Cisco, R, Wheless, L, Cheng, T-Y, Tyler, DS, and Pruitt, SK. "Induction of anti-melanoma CTL response using DC transfected with mutated mRNA encoding full-length Melan-A/MART-1 antigen with an A27L amino acid substitution." Cellular Immunology 224, no. 2 (2003): 85-96. Full Text
  - Onaitis, M, Kalady, MF, Pruitt, S, and Tyler, DS. "Dendritic cell gene therapy." Surg Oncol Clin N Am 11, no. 3 (July 2002): 645-660. (Review) Link to Item
  - Kalady, MF, Onaitis, MW, Padilla, KM, Emani, S, Tyler, DS, and Pruitt, SK. "Enhanced dendritic cell antigen presentation in RNA-based immunotherapy." J Surg Res 105, no. 1 (June 1, 2002): 17-24. Full Text Link to Item
  - Bartlett, JA, Miralles, GD, Sevin, AD, Silberman, M, Pruitt, SK, Ottinger, J, Gryszowska, V, Fiscus, SA, Bucy, RP, and ACTG 380 Study Team, . "Addition of cyclophosphamide to antiretroviral therapy does not diminish the cellular reservoir in HIV-infected persons." Aids Research and Human Retroviruses 18, no. 8 (May 2002): 535-543. Full Text
  - Raj, GV, Pruitt, SK, Lilly, S, Madden, JT, and Price, DT. "Multimodal therapy for stage IV adult Wilms tumor." J Urol 165, no. 4 (April 2001): 1202-. Link to Item
  - Heiser, A, Maurice, MA, Yancey, DR, Wu, NZ, Dahm, P, Pruitt, SK, Boczkowski, D, Nair, SK, Ballo, MS, Gilboa, E, and Vieweg, J. "Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA." Journal of Immunology (Baltimore, Md. : 1950) 166, no. 5 (March 2001): 2953-2960. Full Text
  - White, DC, Schuler, FR, Pruitt, SK, Culhane, DK, Seigler, HF, Coleman, RE, and Tyler, D. "Timing of sentinel lymph node mapping after lymphoscintigraphy." Surgery 126, no. 2 (August 1999): 156-161. Link to Item
  - Dong, XD, Abdel-Wahab, Z, Dematos, P, Fong, T, Pruitt, SK, and Seigler, HF. "MCA106 fibrosarcoma cells transduced with granulocyte/macrophage colony-stimulating factor are not superior to the wild-type cells in suppressing the growth of hepatic metastases." J Surg Oncol 71, no. 1 (May 1999): 36-45. Link to Item
  - Pruitt, SK, Bollinger, RR, Collins, BH, Marsh, HC, Levin, JL, Rudolph, AR, Baldwin, WM, and Sanfilippo, F. "Effect of continuous complement inhibition using soluble complement receptor type 1 on survival of pig-to-primate cardiac xenografts." Transplantation 63, no. 6 (March 27, 1997): 900-902. Link to Item
  - Davis, EA, Jakobs, F, Pruitt, SK, Greene, PS, Qian, Z, Lam, TT, Tseng, E, Levin, JL, Baldwin, WM, and Sanfilippo, F. "Overcoming rejection in pig-to-primate cardiac xenotransplantation." Transplant Proc 29, no. 1-2 (February 1997): 938-939. Link to Item
  - Davis, EA, Pruitt, SK, Greene, PS, Ibrahim, S, Lam, TT, Levin, JL, Baldwin, WM, and Sanfilippo, F. "Inhibition of complement, evoked antibody, and cellular response prevents rejection of pig-to-primate cardiac xenografts." Transplantation 62, no. 7 (October 15, 1996): 1018-1023. Link to Item
  - Pruitt, SK, Baldwin, WM, and Sanfilippo, F. "The role of C3a and C5a in hyperacute rejection of guinea pig-to-rat cardiac xenografts." Transplant Proc 28, no. 2 (April 1996): 596-. Link to Item
  - Pruitt, SK, Bollinger, RR, Collins, BH, Marsh, HC, Levin, JL, Rudolph, AR, Baldwin, WM, and Sanfilippo, F. "Continuous complement (C) inhibition using soluble C receptor type 1 (sCR1): effect on hyperacute rejection (HAR) of pig-to-primate cardiac xenografts." Transplant Proc 28, no. 2 (April 1996): 756-. Link to Item
  - Brauer, RB, Baldwin, WM, Wang, D, Pruitt, SK, Klein, AS, and Sanfilippo, F. "Functional activity of anti-C6 antibodies elicited in C6-deficient rats reconstituted by liver allografts. Ability to inhibit hyperacute rejection of discordant cardiac xenografts." Transplantation 61, no. 4 (February 27, 1996): 588-594. Link to Item
  - Baldwin, WM, Pruitt, SK, Brauer, RB, Daha, MR, and Sanfilippo, F. "Complement in organ transplantation. Contributions to inflammation, injury, and rejection." Transplantation 59, no. 6 (March 1995): 797-808. (Review)
  - Brauer, RB, Baldwin, WM, Pruitt, SK, and Sanfilippo, F. "Survival of guinea pig cardiac xenografts in C6-deficient PVG rats treated with monoclonal antibody to CD18." Transplant Proc 26, no. 3 (June 1994): 1251-. Link to Item
  - Pruitt, SK, Kirk, AD, Bollinger, RR, Marsh, HC, Collins, BH, Levin, JL, Mault, JR, Heinle, JS, Ibrahim, S, and Rudolph, AR. "The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts." Transplantation 57, no. 3 (February 1994): 363-370.
  - Brauer, RB, Baldwin, WM, Daha, MR, Pruitt, SK, and Sanfilippo, F. "Use of C6-deficient rats to evaluate the mechanism of hyperacute rejection of discordant cardiac xenografts." Journal of Immunology (Baltimore, Md. : 1950) 151, no. 12 (December 1993): 7240-7248.
  - Pruitt, SK, Baldwin, WM, Barth, RN, and Sanfilippo, F. "The effect of xenoreactive antibody and B cell depletion on hyperacute rejection of guinea pig-to-rat cardiac xenografts." Transplantation 56, no. 6 (December 1993): 1318-1324.
  - Brauer, RB, Baldwin, WM, Pruitt, SK, and Sanfilippo, F. "Rat strain differences in complement activity correlate with hyperacute rejection of guinea pig cardiac xenografts." Transplant Proc 25, no. 5 (October 1993): 2848-2849. Link to Item
  - Pruitt, SK, Weinstock, D, Suyemoto, MM, Sanfilippo, F, and Baldwin, WM. "The effect of bursectomy on natural xenoreactive antibodies and vascularized rat cardiac xenograft rejection in the chicken." Transplantation 55, no. 5 (May 1993): 1139-1144. Link to Item
  - Pruitt, SK, Weinstock, D, Suyemoto, MM, Sanfilippo, F, and Baldwin, WM. "Effect of bursectomy on deposition of natural xenoreactive antibodies and complement within rat cardiac xenografts in the chicken." Transplant Proc 25, no. 1 Pt 1 (February 1993): 435-437. Link to Item
  - Pruitt, SK, Weinstock, D, Suyemoto, MM, Sanfilippo, F, and III, WMB. "Effect of bursectomy on deposition of natural xenoreactive antibodies and complement within rat cardiac xenografts in the chicken." Transplantation Proceedings 25, no. 1 (1993): 435-437.
  - Baldwin, WM, Weinstock, D, Suyemoto, MM, Pruitt, SK, Lin, SS, Jones, LR, and Sanfilippo, F. "Effects of bursectomy and rat skin xenografts on natural antibodies in chickens." Transplant Proc 24, no. 2 (April 1992): 472-473. Link to Item
  - Pruitt, SK, Baldwin, WM, Marsh, HC, Lin, SS, Yeh, CG, and Bollinger, RR. "Effect of soluble complement receptor type 1 on natural antibody levels during xenograft rejection." Transplant Proc 24, no. 2 (April 1992): 477-478. Link to Item
  - Pruitt, SK, Baldwin, WM, Marsh, HC, Lin, SS, Yeh, CG, and Bollinger, RR. "The effect of soluble complement receptor type 1 on hyperacute xenograft rejection." Transplantation 52, no. 5 (November 1991): 868-873. Link to Item
  - Baldwin, W, Pruitt, S, and Sanfilippo, F. "Alloantibodies: Basic and clinical concepts." Transplantation Reviews 5, no. 2 (April 1991): 100-119. Full Text
  - Pruitt, SK, and Bollinger, RR. "The effect of soluble complement receptor type 1 on hyperacute allograft rejection." J Surg Res 50, no. 4 (April 1991): 350-355. Link to Item
  - Pruitt, SK, Halperin, EC, and Bollinger, RR. "The effect of 15-deoxyspergualin on hamster-to-rat cardiac xenograft survival." Transplant Proc 23, no. 1 Pt 1 (February 1991): 585-586. Link to Item
  - Pruitt, SK, Halperin, EC, and Bollinger, RR. "The effect of 15-deoxyspergualin on hamster-to-rat cardiac xenograft survival." Transplantation Proceedings 23, no. 1 I (1991): 585-586.
  - Bessey, PQ, Pruitt, SK, and Wilmore, DW. "The effect of free fatty acids on insulin-mediated glucose uptake." J Surg Res 36, no. 5 (May 1984): 462-469. Link to Item
- Other Articles
  - Zhong, P, Xing, F, Huang, X, Zhu, H, Lo, HW, Zhong, X, Pruitt, S, and Robertson, C. "HIFU as a neoadjuvant therapy in cancer treatment." Aip Conference Proceedings 1359 (October 13, 2011): 289-294. Full Text
  - Quigley, RL, Pruitt, SK, Pappas, TN, and Akwari, O. "Primary hypertrophic pyloric stenosis in the adult." Arch Surg 125, no. 9 (September 1990): 1219-1221. Link to Item
- Conference Papers
  - Rosa, ND, Lyman, GH, Silbermins, D, Valsecchi, ME, Wong, S, Pruitt, SK, and Lee, WT. "Systematic review of ^99mTc human serum albumin and ^99mTc sulfur colloid studies of sentinel lymph node biopsy of cutaneous melanoma of the head and neck." 2011. Full Text
  - Beasley, GM, Selim, A, McMahon, NS, Coleman, A, Abernethy, AP, Nelson, K, Pruitt, SK, Seigler, H, Wong, T, Onaitis, M, and Tyler, DS. "Prospective Evaluation of PET/CT as a Surveillance Tool to Define Response to Therapy and Identify New Recurrent Disease in Patients with Locally Advanced Melanoma Undergoing Regional Chemotherapy Treatment with Melphalan." February 2010. Link to Item
  - De Rosa, N, II, HJE, Marcello, J, Tyler, DS, Scheri, RP, Pruitt, SK, Wheeler, JL, and Abernethy, AP. "Patterns of Recurrence in Melanoma and the Impact on Survival." February 2010. Link to Item
  - Dannull, J, Tyler, DS, and Pruitt, SK. "Immunostimulatory and migratory properties of human monocyte-derived dendritic cells (DC) matured in the presence of the cysteinyl leukotrienes (cysLTs) LTC4 and LTD4." April 2008. Link to Item
  - Grubbs, E, Bennett, K, Westlund, R, Schuler, F, Bentley, R, Wilke, LG, Georgaide, G, Olson, JA, and Pruitt, SK. "Sentinel lymph node biopsy in breast cancer: How many nodes need to be removed?." February 2007. Link to Item
  - Yoo, J, Augustine, CK, Yoshimoto, Y, Petersen, RP, Pruitt, SK, Ali-Osman, F, and Tyler, DS. "Role of BAY 43-9006 in combination with temozolomide and melphalan in metastatic melanoma." February 2006. Link to Item
  - Yoshimoto, Y, Yoo, JS, Augustine, CK, Pruitt, SK, Friedman, HS, and Tyler, DS. "The role of chemoresistance in regional infusion therapy for melanoma." February 2006. Link to Item
  - Yoo, JS, Yoshimoto, Y, Petersen, RP, Pruitt, SK, Ali-Osman, F, and Tyler, DS. "Glutathione S-transferase as a marker of metastatic potential in malignant melanoma." September 2005. Full Text Link to Item
  - Abdel-Wahab, OI, Grubbs, E, Cheng, TY, Viglianti, B, Ueno, T, Curtiss, S, Pruitt, SK, Dewhirst, MW, and Tyler, DS. "Role of hyperthermia in regional alkylating agent chemotherapy." February 2004. Full Text Link to Item
  - Cisco, RM, Abdel-Wahab, Z, Dannull, J, Tyler, DS, and Pruitt, SK. "Transfection with RNA encoding a dominant positive toll-like receptor 4 (TLR4) construct induces maturation of human monocyte-derived dendritic cells (DC) in the absence of exogenous maturation stimuli." September 2003. Link to Item
  - Kalady, MF, Onaitis, MW, Abdul-Wahab, Z, Emani, S, Pruitt, SK, and Tyler, DS. "Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific anti-pancreatic cancer T cells." April 2003. Full Text Link to Item
  - Grubbs, EG, Pruitt, SK, and Tyler, DS. "Quantitative PCR: Identifying novel tumor markers in pancreatic cancer." January 2003. Link to Item
  - White, DC, Hamza, A, Nielson, K, Lyerly, HK, Steele, SM, Pruitt, SK, Leight, GS, and Olson, JA. "Thoracic paravertebral blockade for breast sentinel lymph node biopsy: Experience in 137 patients." January 2002. Link to Item
  - Pruitt, SK, Baldwin, WM, Bollinger, R, March, HC, and Sanfillippo, F. "Soluble complement receptor and hyperacute rejection." 1996. Link to Item
  - PRUITT, SK, HALPERIN, EC, and BOLLINGER, RR. "THE EFFECT OF 15-DEOXYSPERGUALIN ON HAMSTER-TO-RAT CARDIAC XENOGRAFT SURVIVAL." February 1991. Link to Item

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Education, Training, & Certifications

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