Scholars@Duke
Sean Michael O'Brien

Sean Michael O'Brien

Associate Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
sean.m.obrien@duke.edu
Duke Box 3850, Durham, NC 27710
200 Morris Street, 7816 200 Morris, Durham, NC 27701

Featured Works

Exploring the behavior of hospital composite performance measures: an example from coronary artery bypass surgery.

Journal article Circulation · December 18, 2007 Featured Publication BACKGROUND: Composite scores that combine several performance measures into a single ranking are becoming the accepted metric for assessing hospital performance. In particular, the Centers for Medicare & Medicaid Services Hospital Quality Incentive Demonst ... Full text Link to item Cite

Trends in tuberculosis/human immunodeficiency virus comorbidity, United States, 1993-2004.

Journal article Arch Intern Med · December 10, 2007 Featured Publication BACKGROUND: To our knowledge, this is the first assessment of trends in tuberculosis (TB)/human immunodeficiency virus (HIV) comorbidity in the United States based on national TB surveillance data. METHODS: We analyzed all incident TB cases reported to the ... Full text Link to item Cite

Accuracy of the aristotle basic complexity score for classifying the mortality and morbidity potential of congenital heart surgery operations.

Journal article Ann Thorac Surg · December 2007 Featured Publication BACKGROUND: The Aristotle Basic Complexity Score (ABC score) was derived by consensus of an international surgeon panel to facilitate assessment of surgical performance for quality improvement in congenital heart surgery. The utility of the ABC score depen ... Full text Link to item Cite

Identifying high-quality hospitals: consult the ratings or flip a coin?

Journal article Arch Intern Med · July 9, 2007 Featured Publication Full text Link to item Cite

Contemporary impact of state certificate-of-need regulations for cardiac surgery: an analysis using the Society of Thoracic Surgeons' National Cardiac Surgery Database.

Journal article Circulation · November 14, 2006 Featured Publication BACKGROUND: Prior research using administrative data associated certificate-of-need (CON) regulation for open heart surgery with higher hospital coronary artery bypass grafting (CABG) volume and lower CABG operative mortality rates in elderly patients. It ... Full text Link to item Cite

Bayesian multivariate logistic regression.

Journal article Biometrics · September 2004 Featured Publication Bayesian analyses of multivariate binary or categorical outcomes typically rely on probit or mixed effects logistic regression models that do not have a marginal logistic structure for the individual outcomes. In addition, difficulties arise when simple no ... Full text Link to item Cite

Cutpoint selection for categorizing a continuous predictor.

Journal article Biometrics · June 2004 Featured Publication This article presents a new approach for choosing the number of categories and the location of category cutpoints when a continuous exposure variable needs to be categorized to obtain tabular summaries of the exposure effect. The optimum categorization is ... Full text Link to item Cite