Scholars@Duke
Hilliard Foster Seigler

Hilliard Foster Seigler

Professor Emeritus of Surgery
Surgical Oncology
seigl001@mc.duke.edu
Box 3966 Med Ctr, Durham, NC 27710
Room 469 Seeley Mudd Bldg, Durham, NC 27710

Featured Works

Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.

Journal article J Surg Oncol · February 2003 Featured Work The rare finding of heterotopic ossification in a case of primary rectal adenocarcinoma is described along with a review of the literature. Immunohistochemistry for a bone morphogenic protein (BMP-2) and fibroblast growth factor (FGF-2), both of which indu ... Full text Link to item Cite

The long-term clinical course of patients with cutaneous melanoma.

Journal article Cancer · September 15, 2002 Featured Work BACKGROUND: The clinical course of cutaneous melanoma is associated with pathologic and clinical factors, such as thickness, ulceration, and location of tumor and gender of the patient. The authors used a parametric survival model that incorporated a cured ... Full text Link to item Cite

Mutations of the BRAF gene in human cancer.

Journal article Nature · June 27, 2002 Featured Work Cancers arise owing to the accumulation of mutations in critical genes that alter normal programmes of cell proliferation, differentiation and death. As the first stage of a systematic genome-wide screen for these genes, we have prioritized for analysis si ... Full text Link to item Cite

Long-term survival in 2,505 patients with melanoma with regional lymph node metastasis.

Journal article Ann Surg · June 2002 Featured Work OBJECTIVE: To examine the long-term outcomes of patients with melanoma metastatic to regional lymph nodes. SUMMARY BACKGROUND DATA: Regional lymph node metastasis is a major determinant of outcome for patients with melanoma, and the presence of regional ly ... Full text Link to item Cite

Poor outcome and quality of life in female patients undergoing secondary surgery for recurrent peptic ulcer disease.

Journal article J Gastrointest Surg · 2002 Featured Work Secondary peptic ulcer surgery is uncommon given the success of a wide variety of medical therapies, plus the good outcome expected after primary peptic ulcer surgery. Early reports of secondary peptic ulcer surgery in the 1950s and 1960s suggested good lo ... Full text Link to item Cite