Scholars@Duke
Shanti Narayanasamy

Shanti Narayanasamy

Adjunct Assistant Professor of Global Health
Duke Global Health Institute

Scholarly Works

Implementation of a Hospital in the Home model for delivery of long-acting injectable antiretroviral therapy to people living with HIV: development, integration and early experience.

Journal article Sexual health · April 2026 BackgroundLong-acting injectable cabotegravir/rilpivirine provides an alternative to daily oral antiretroviral therapy for people living with HIV, but is limited by its clinic-based delivery model. The aim of this study was to describe the impleme ... Full text Cite

Clinical Performance of a Mp1p Antibody Detection Immunoassay For Talaromycosis.

Journal article medRxiv · February 14, 2026 BACKGROUND: Talaromycosis, caused by the fungus Talaromyces marneffei, is a leading cause of HIV-associated death in Southeast Asia. Current culture-based diagnosis only identifies late-stage infection, limiting understanding of disease burden and disease ... Full text Link to item Cite

Mixed methods implementation research of oral antiviral treatment for COVID-19 in low- and middle-income countries: a study protocol.

Journal article BMJ Open · September 18, 2025 INTRODUCTION: There is an absence of real-world evidence, especially from low- and middle-income countries (LMICs), on the implementation successes and challenges of COVID-19 Test and Treat (T&T) programmes. In 2022, nirmatrelvir/ritonavir was provided as ... Full text Open Access Link to item Cite

Recommendations for Enhancing COVID-19 Test and Treat Programs in Four African Countries: Insights and Strategies from a Qualitative Study

Preprint · March 25, 2025 ABSTRACTSub-Saharan Africa had a significant burden of infections and deaths from COVID-19. However, throughout the pandemic, the region experienced delays and more limited access to diagnostics and treatme ... Full text Cite

Lessons From COVID-19 for Pandemic Preparedness: Proceedings From a Multistakeholder Think Tank.

Journal article Clin Infect Dis · December 15, 2023 While the coronavirus disease 2019 (COVID-19) pandemic continues to present global challenges, sufficient time has passed to reflect on lessons learned and use those insights to inform policy and approaches to prepare for the next pandemic. In May 2022, th ... Full text Link to item Cite

RADx-UP Testing Core: Access to COVID-19 Diagnostics in Community-Engaged Research with Underserved Populations.

Journal article J Clin Microbiol · August 23, 2023 Research on the COVID-19 pandemic revealed a disproportionate burden of COVID-19 infection and death among underserved populations and exposed low rates of SARS-CoV-2 testing in these communities. A landmark National Institutes of Health (NIH) funding init ... Full text Open Access Link to item Cite

Global inequity of COVID-19 diagnostics: challenges and opportunities.

Journal article J Epidemiol Community Health · October 6, 2022 Full text Link to item Cite

A global call for talaromycosis to be recognised as a neglected tropical disease.

Journal article Lancet Glob Health · November 2021 Talaromycosis (penicilliosis) is an invasive mycosis that is endemic in tropical and subtropical Asia. Talaromycosis primarily affects individuals with advanced HIV disease and other immunosuppressive conditions, and the disease disproportionally affects p ... Full text Link to item Cite

Curvularia alcornii Aortic Pseudoaneurysm Following Aortic Valve Replacement: Case Report and Review of the Literature.

Journal article Open Forum Infect Dis · November 2021 We report the first case of Curvularia alcornii aortic pseudoaneurysm following bioprosthetic aortic valve replacement in an immunocompetent host. Infection was complicated by septic emboli to multiple organs. Despite aggressive surgical intervention and a ... Full text Open Access Link to item Cite

Pulmonary Talaromycosis: A Window into the Immunopathogenesis of an Endemic Mycosis.

Journal article Mycopathologia · October 2021 Talaromycosis is an invasive mycosis caused by the thermally dimorphic saprophytic fungus Talaromyces marneffei (Tm) endemic in Asia. Like other endemic mycoses, talaromycosis occurs predominantly in immunocompromised and, to a lesser extent, immunocompete ... Full text Open Access Link to item Cite

Curvularia alcornii Infection.

Journal article N Engl J Med · June 17, 2021 Full text Link to item Cite

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

Journal article Nat Commun · April 15, 2021 Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydroxychloroquine a ... Full text Open Access Link to item Cite

Cure of Limb-Threatening XDR Pseudomonas aeruginosa Infection: Combining Genome Sequencing, Therapeutic Drug Level Monitoring, and Surgical Debridement.

Journal article Open forum infectious diseases · January 2021 We describe a case of limb-threatening osteomyelitis and metalware infection with carbapenemase-producing extensively drug-resistant Pseudomonas aeruginosa successfully cured with aggressive surgical debridement and combined intravenous fosfomycin a ... Full text Cite

Social Disadvantage, Politics, and SARS-CoV-2 Trends: A County-Level Analysis of United States Data

Journal article · 2020 Background Understanding the epidemiology of SARS-CoV-2 is essential for public health control efforts. Social, demographic, and political characteristics at the US county level might be associated with the trajectories of SARS-CoV-2 case incidenc ... Full text Cite

Donor-Derived Mycoplasma hominis and an Apparent Cluster of M. hominis Cases in Solid Organ Transplant Recipients.

Journal article Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · October 2017 BackgroundInvasive and disseminated Mycoplasma hominis infections are well recognized but uncommon complications in solid organ transplant recipients. In a single center, a cluster of M. hominis infections were identified in lung transplant recipi ... Full text Cite

Clinical Characteristics and Laboratory Identification of Aerococcus Infections: An Australian Tertiary Centre Perspective.

Journal article International journal of microbiology · January 2017 Aerococci uncommonly cause urinary tract (UTI) and bloodstream infections (BSI). The clinical characteristics and laboratory identification rates of Aerococcus in the Australian context are unknown. A retrospective observational cohort study of pati ... Full text Cite

Visible age-related signs in an Arab patient presenting with a myocardial infarction.

Journal article Journal of the Saudi Heart Association · April 2015 Full text Cite

Proof of age required--estimating age in adults without birth records.

Journal article Australian family physician · July 2010 BackgroundMany adults from refugee source countries do not have documents of birth, either because they have been lost in flight, or because the civil infrastructure is too fragile to support routine recording of birth. In Western countries, date ... Cite