Overview
Shelby D. Reed, PhD, is Professor in the Departments of Population Health Sciences and Medicine at Duke University’s School of Medicine. She is the director of the Center for Informing Health Decisions and Therapeutic Area leader for Population Health Sciences at the Duke Clinical Research Institute (DCRI). She also is core faculty at the Duke-Margolis Center for Health Policy. Dr. Reed has over 20 years of experience leading multidisciplinary health outcomes research studies. Dr. Reed has extensive expertise in designing and conducting trial-based and model-based cost-effectiveness analyses of diagnostics, drugs and patient-centered interventions. In 2016, she co-founded the Preference Evaluation Research (PrefER) Group at the DCRI, and she currently serves as its director. She and the group are frequently sought to conduct stated-preference studies to inform regulatory decisions, health policy, care delivery, value assessment and clinical decision making with applied projects spanning a wide range of therapeutic areas. She served as President for ISPOR in 2017-2018, and she currently is Past-Chair of the Society’s Health Science Policy Council.
Areas of expertise: Health Economics, Health Measurement, Stated Preference Research, Health Policy, and Health Services Research
Current Duke Appointments & Affiliations
Recent Scholarly Works
Physical rehabilitation for older patients with acute HFpEF (REHAB-HFpEF) trial: Design and rationale.
Journal article Am Heart J · July 2026 RATIONALE: Older patients hospitalized for acute decompensated heart failure with preserved ejection fraction (HFpEF) experience persistently poor outcomes, including physical disability, cognitive impairment, depression, impaired health-related quality of ... Full text Link to item CiteGuidance or Misdirection? Unpacking the Role of Feedback in Health Preference Assessments.
Conference Health Econ · June 2026 This study investigated the impact of providing feedback to respondents on a dominance-structured choice task on subsequent choice behavior in a discrete choice experiment (DCE). The DCE was conducted among 626 patients with heart failure. Respondents were ... Full text Link to item CitePatient-Centered Evaluation of Anticoagulation in Atrial Fibrillation.
Journal article NEJM Evid · June 2026 BACKGROUND: Prior analyses of trials comparing direct oral anticoagulants (DOACs) to warfarin in atrial fibrillation (AF) have not routinely incorporated patient preferences, despite substantial variation in how patients value the trade-off between outcome ... Full text Link to item CiteRecent Grants
State reproductive health policy as a determinant for maternal health
ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2030Duke Women's Reproductive Health Research Scholars
Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2020 - 2030Quantifying Patient Preference Information in Small-Scale Studies for Regulatory Decision Making
ResearchCo Investigator · Awarded by Food and Drug Administration · 2025 - 2028View All Grants