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Eun-Sil Shelley Hwang

Mary and Deryl Hart Distinguished Professor of Surgery, in the School of Medicine
Surgical Oncology

Current Appointments & Affiliations


Mary and Deryl Hart Distinguished Professor of Surgery, in the School of Medicine · 2018 - Present Surgical Oncology, Surgery
Professor of Surgery · 2012 - Present Surgical Oncology, Surgery
Vice-Chair of Research in the Department of Surgery · 2015 - Present Surgery, Clinical Science Departments
Professor of Radiology · 2017 - Present Radiology, Clinical Science Departments
Member of the Duke Cancer Institute · 2011 - Present Duke Cancer Institute, Institutes and Centers
Core Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Institutes and Centers

In the News


Published January 13, 2025
Dr. Shelley Hwang Wants Alternatives to Surgery for Some Breast Cancers
Published December 16, 2024
Non-Surgical Options for Some Early Breast Cancer
Published March 29, 2024
Center for Precision Health Welcomes New Faculty Leaders

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Recent Publications


Neoplastic Immune Mimicry Potentiates Breast Tumor Progression.

Journal Article Cancer Res · February 2, 2026 UNLABELLED: Dedifferentiation programs are commonly enacted during breast cancer progression to enhance tumor cell fitness. Increased cellular plasticity within the neoplastic compartment of tumors correlates with disease aggressiveness, often culminating ... Full text Link to item Cite

Spatially Discontinuous Mutation Topographies in Ductal Carcinoma In Situ Reveal Noncompetitive Growth Dynamics.

Journal Article Cancer Res · December 15, 2025 UNLABELLED: Preinvasive breast cancer, or ductal carcinoma in situ (DCIS), shares many morphologic and genomic features with invasive breast cancer, yet most DCIS tumors remain indolent over decades. In this study, we performed spatial analyses of somatic ... Full text Link to item Cite

Cross-National Radiomics Validation Using Mammography to Predict Occult Invasion in Ductal Carcinoma in Situ.

Journal Article Radiology · November 2025 Background Patients diagnosed with ductal carcinoma in situ (DCIS) may also have undetected invasive breast cancer. Radiomic features of calcifications at mammography can predict occult invasive disease among women diagnosed with DCIS at core-needle biopsy ... Full text Link to item Cite
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Recent Grants


2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

Duke Research Training Program in Surgical Oncology

Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 2024 - 2029

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029

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Education, Training & Certifications


University of California, Berkeley · 2006 M.P.H.
University of California, Los Angeles · 1991 M.D.