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Eun-Sil Shelley Hwang

Mary and Deryl Hart Distinguished Professor of Surgery, in the School of Medicine
Surgical Oncology

Current Duke Appointments & Affiliations


Mary and Deryl Hart Distinguished Professor of Surgery, in the School of Medicine · 2018 - Present Surgical Oncology, Surgery
Professor of Surgery · 2012 - Present Surgical Oncology, Surgery
Professor of Radiology · 2017 - Present Radiology, Clinical Science Departments
Member of the Duke Cancer Institute · 2011 - Present Duke Cancer Institute, Institutes and Centers
Core Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Institutes and Centers

Recent News Items


Published January 13, 2025
Dr. Shelley Hwang Wants Alternatives to Surgery for Some Breast Cancers
Published December 16, 2024
Non-Surgical Options for Some Early Breast Cancer
Published March 29, 2024
Center for Precision Health Welcomes New Faculty Leaders

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Recent Scholarly Works


OpenIMC: an open-source platform for analyzing single-cell and spatial proteomics by imaging mass cytometry.

Journal article BMC Bioinformatics · June 30, 2026 BACKGROUND: Imaging Mass Cytometry (IMC) enables highly multiplexed, spatially resolved single-cell proteomics, providing simultaneous measurement of dozens of protein markers while preserving tissue architecture. Despite its analytical power, IMC data ana ... Full text Link to item Cite

CSF1R Inhibition with Chemotherapy Relieves Systemic Immune Suppression in Patients with Metastatic Triple-Negative Breast Cancer and Boosts anti-PD-1 Efficacy in Transgenic Mammary Tumors.

Journal article Clin Cancer Res · March 27, 2026 PURPOSE: Significant correlations exist between presence of intratumoral macrophages, tumor progression, and poor outcomes in triple-negative breast cancer (TNBC) with limited therapeutic options available for advanced stage disease. Preclinical studies re ... Full text Link to item Cite

Neoplastic Immune Mimicry Potentiates Breast Tumor Progression.

Journal article Cancer Res · February 2, 2026 UNLABELLED: Dedifferentiation programs are commonly enacted during breast cancer progression to enhance tumor cell fitness. Increased cellular plasticity within the neoplastic compartment of tumors correlates with disease aggressiveness, often culminating ... Full text Link to item Cite
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Recent Grants


Post-Recurrence Survival in Patients with Recurrent Breast Cancer: Identifying Key Predictors and Standardizing Assessments

ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2031

2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

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Education


University of California, Berkeley · 2006 M.P.H.
University of California, Los Angeles · 1991 M.D.