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Eun-Sil Shelley Hwang

Mary and Deryl Hart Distinguished Professor of Surgery, in the School of Medicine
Surgical Oncology

Current Appointments & Affiliations


Mary and Deryl Hart Distinguished Professor of Surgery, in the School of Medicine · 2018 - Present Surgical Oncology, Surgery
Professor of Surgery · 2012 - Present Surgical Oncology, Surgery
Vice-Chair of Research in the Department of Surgery · 2015 - Present Surgery, Clinical Science Departments
Professor of Radiology · 2017 - Present Radiology, Clinical Science Departments
Member of the Duke Cancer Institute · 2011 - Present Duke Cancer Institute, Institutes and Centers
Core Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Initiatives & Academic Support Units

In the News


Published January 13, 2025
Dr. Shelley Hwang Wants Alternatives to Surgery for Some Breast Cancers
Published December 16, 2024
Non-Surgical Options for Some Early Breast Cancer
Published March 29, 2024
Center for Precision Health Welcomes New Faculty Leaders

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Recent Publications


Single-Cell Expression Analysis of Ductal Carcinoma In Situ Identifies Complex Genotypic-Phenotypic Relationships Altering Epithelial Composition.

Journal Article Cancer Res · June 16, 2025 UNLABELLED: Ductal carcinoma in situ (DCIS) is a risk factor for subsequent invasive breast cancer (IBC). To identify events in DCIS that lead to invasive cancer, we performed single-cell RNA sequencing on DCIS lesions and matched normal breast tissue. Inf ... Full text Link to item Cite

Genomic alterations are associated with response to aromatase inhibitor therapy for ER-positive postmenopausal ductal carcinoma in situ: (CALGB 40903, Alliance).

Journal Article Breast Cancer Res · February 20, 2025 PURPOSE: CALGB 40903 (Alliance) was a phase II single arm multicenter trial conducted in postmenopausal patients diagnosed with estrogen-receptor (ER) positive breast ductal carcinoma in situ (DCIS) without invasion. Patients were treated with the aromatas ... Full text Link to item Cite

The Association of Care Fragmentation on Overall Survival for Early Stage Breast Cancer.

Journal Article J Surg Res · February 2025 INTRODUCTION: Optimal treatment of stage I-III breast cancer requires multimodal therapies. Patients can receive these therapies at one or multiple facilities. Herein, we evaluated the association of receiving treatment at more than one facility and distan ... Full text Link to item Cite
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Recent Grants


Duke Research Training Program in Surgical Oncology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029

IMPROVE DCIS: Identifying Molecular Predictors of Risk to Objectively Validate Evolution of DCIS

ResearchPrincipal Investigator · Awarded by Stanford University · 2023 - 2027

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Education, Training & Certifications


University of California, Berkeley · 2006 M.P.H.
University of California, Los Angeles · 1991 M.D.