Sheng Luo | Scholars@Duke

Sheng Luo
Associate Professor of Biostatistics & Bioinformatics

Current Research Interests

Longitudinal and survival data analysis, functional data analysis, genetic and genomic data, and clinical trial design

Current Appointments & Affiliations

Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2017
Member of the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2017

Contact Information

2424 Erwin Road, Suite 1102, 11082 Hock Plaza, Durham, NC 27705
Duke Box 2721, Durham, NC 27710
sheng.luo@duke.edu (919) 668-8038
CV

Background
Education, Training, & Certifications
- Ph.D., Johns Hopkins University 2008
Recognition
In the News
- NOV 27, 2018
  
  The DCRI’s Sheng Luo on the benefit of biostatistics
- JAN 8, 2018
  
  Researchers develop new model to predict progression to Alzheimer’s in patients with mild cognitive impairment
- MAY 7, 2017 IOS Press
  
  Prediction of Conversion to Alzheimer’s Disease with Longitudinal Measures and Time-To-Event Data
Awards & Honors
- 5U01NS043127. NIH/NINDS. June 1, 2016
- R01NS091307. NIH/NINDS. September 30, 2015
Expertise
Subject Headings
Research
Selected Grants
- Shared genetic, epigenetic, and transcriptomic profiles between AD and PTSD: molecular insights into the heterogeneity of neuropsychiatric symptoms in Alzheimers Disease awarded by National Institutes of Health 2018 - 2019
- Statistical Methods for Clinical Trials with Multivariate Longitudinal Outcomes awarded by National Institutes of Health 2017 - 2019
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Ge, J, Liu, H, Qian, D, Wang, X, Moorman, PG, Luo, S, Hwang, S, and Wei, Q. "Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large-scale analysis of 14 published GWAS datasets in the DRIVE study." International Journal of Cancer (April 26, 2019). Full Text
  - Xu, X, Qian, D, Liu, H, Cruz, D, Luo, S, Walsh, KM, Abbruzzese, JL, Zhang, X, and Wei, Q. "Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk." Molecular Carcinogenesis (April 17, 2019). Full Text Open Access Copy
  - Guo, Y, Feng, Y, Liu, H, Luo, S, Clarke, JW, Moorman, PG, Su, L, Shen, S, Christiani, DC, and Wei, Q. "Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial." Molecular Carcinogenesis (April 15, 2019). Full Text Open Access Copy
  - Li, K, Luo, S, Yuan, S, and Mt-Isa, S. "A Bayesian approach for individual-level drug benefit-risk assessment." Statistics in Medicine (April 15, 2019). Full Text
  - Yang, W, Liu, H, Duan, B, Xu, X, Carmody, D, Luo, S, Walsh, KM, Abbruzzese, JL, Zhang, X, Chen, X, and Wei, Q. "Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk." Cancer Science (April 10, 2019). Full Text
  - Qian, D, Liu, H, Wang, X, Ge, J, Luo, S, Patz, EF, Moorman, PG, Su, L, Shen, S, Christiani, DC, and Wei, Q. "Potentially functional genetic variants in the complement-related immunity gene-set are associated with non-small cell lung cancer survival." International Journal of Cancer 144, no. 8 (April 2019): 1867-1876. Full Text Open Access Copy
  - Dai, W, Liu, H, Xu, X, Ge, J, Luo, S, Zhu, D, Amos, CI, Fang, S, Lee, JE, Li, X, Nan, H, Li, C, and Wei, Q. "Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival." International Journal of Cancer (February 8, 2019). Full Text Open Access Copy
  - Chen, K, Liu, H, Liu, Z, Luo, S, Patz, EF, Moorman, PG, Su, L, Shen, S, Christiani, DC, and Wei, Q. "Genetic variants in RUNX3, AMD1 and MSRA in the methionine metabolic pathway and survival in nonsmall cell lung cancer patients." International Journal of Cancer (January 16, 2019). Full Text Open Access Copy
  - Li, K, and Luo, S. "Bayesian Functional Joint Models for Multivariate Longitudinal and Time-to-Event Data." Computational Statistics & Data Analysis 129 (January 2019): 14-29. Full Text
  - Wang, J, and Luo, S. "Joint modeling of multiple repeated measures and survival data using multidimensional latent trait linear mixed model." Statistical Methods in Medical Research (October 11, 2018): 962280218802300-null. Full Text
  - Luo, S, Ren, X, Han, W, Goetz, CG, and Stebbins, GT. "Missing Data in the Unified Dysksinesia Rating Scale (UDysRS)." Movement Disorders Clinical Practice 5, no. 5 (September 2018): 523-526. Full Text
  - Li, K, O'Brien, R, Lutz, M, Luo, S, and Alzheimer's Disease Neuroimaging Initiative, . "A prognostic model of Alzheimer's disease relying on multiple longitudinal measures and time-to-event data." Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association 14, no. 5 (May 2018): 644-651. Full Text
  - Li, K, Yuan, SS, Wang, W, Wan, SS, Ceesay, P, Heyse, JF, Mt-Isa, S, and Luo, S. "Periodic benefit-risk assessment using Bayesian stochastic multi-criteria acceptability analysis." Contemporary clinical trials 67 (April 2018): 100-108. Full Text
  - Zhu, H, DeSantis, SM, and Luo, S. "Joint modeling of longitudinal zero-inflated count and time-to-event data: A Bayesian perspective." Statistical Methods in Medical Research 27, no. 4 (April 2018): 1258-1270. Full Text Open Access Copy
  - Vidoni, ML, Pettee Gabriel, K, Luo, ST, Simonsick, EM, and Day, RS. "Relationship between Homocysteine and Muscle Strength Decline: The Baltimore Longitudinal Study of Aging." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 73, no. 4 (March 2018): 546-551. Full Text Open Access Copy
  - Yang, M, Luo, S, and DeSantis, S. "Bayesian quantile regression joint models: Inference and dynamic predictions." Statistical Methods in Medical Research (January 2018): 962280218784757-null. Full Text
  - Li, L, Luo, S, Hu, B, and Greene, T. "Dynamic Prediction of Renal Failure Using Longitudinal Biomarkers in a Cohort Study of Chronic Kidney Disease." Statistics in biosciences 9, no. 2 (December 2017): 357-378. Full Text Open Access Copy
  - Lin, L-A, Luo, S, Chen, BE, and Davis, BR. "Bayesian analysis of multi-type recurrent events and dependent termination with nonparametric covariate functions." Statistical Methods in Medical Research 26, no. 6 (December 2017): 2869-2884. Full Text Open Access Copy
  - Zitser, J, Peretz, C, Ber David, A, Shabtai, H, Ezra, A, Kestenbaum, M, Brozgol, M, Rosenberg, A, Herman, T, Balash, Y, Gadoth, A, Thaler, A, Stebbins, GT, Goetz, CG, Tilley, BC, Luo, ST, Liu, Y, Giladi, N, and Gurevich, T. "Validation of the Hebrew version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale." Parkinsonism & Related Disorders 45 (December 2017): 7-12. Full Text
  - Leehey, M, Luo, S, Sharma, S, Wills, A-MA, Bainbridge, JL, Wong, PS, Simon, DK, Schneider, J, Zhang, Y, Pérez, A, Dhall, R, Christine, CW, Singer, C, Cambi, F, and Boyd, JT. "Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores." Neurology 89, no. 17 (October 2017): 1789-1794. Full Text Open Access Copy
  - Li, K, and Luo, S. "Functional joint model for longitudinal and time-to-event data: an application to Alzheimer's disease." Statistics in medicine 36, no. 22 (September 2017): 3560-3572. Full Text Open Access Copy
  - Wang, J, and Luo, S. "Multidimensional latent trait linear mixed model: an application in clinical studies with multivariate longitudinal outcomes." Statistics in medicine 36, no. 20 (September 2017): 3244-3256. Full Text Open Access Copy
  - Lin, L-A, Luo, S, and Davis, BR. "Bayesian regression model for recurrent event data with event-varying covariate effects and event effect." Journal of Applied Statistics (August 26, 2017): 1-17. Full Text Open Access Copy
  - Luo, S, Liu, Y, Teresi, JA, Stebbins, GT, and Goetz, CG. "Differential item functioning in the Unified Dyskinesia Rating Scale (UDysRS)." Movement Disorders : Official Journal of the Movement Disorder Society 32, no. 8 (August 2017): 1244-1249. Full Text Open Access Copy
  - Martino, D, Pringsheim, TM, Cavanna, AE, Colosimo, C, Hartmann, A, Leckman, JF, Luo, S, Munchau, A, Goetz, CG, Stebbins, GT, Martinez-Martin, P, and Members of the MDS Committee on Rating Scales Development, . "Systematic review of severity scales and screening instruments for tics: Critique and recommendations." Movement Disorders : Official Journal of the Movement Disorder Society 32, no. 3 (March 2017): 467-473. (Review) Full Text Open Access Copy
  - Chen, G, and Luo, S. "Bayesian hierarchical joint modeling using skew-normal/independent distributions." Communications in Statistics-Simulation and Computation OnlineFirst (2017). (Academic Article) Open Access Copy
  - Gibbons, CH, Simon, DK, Huang, M, Tilley, B, Aminoff, MJ, Bainbridge, JL, Brodsky, M, Freeman, R, Goudreau, J, Hamill, RW, Luo, S, Singer, C, Videnovic, A, Bodis-Wollner, I, and Wong, PS. "Autonomic and electrocardiographic findings in Parkinson’s disease." Autonomic Neuroscience 205 (2017): 93-98. (Academic Article) Open Access Copy
  - Li, K, Chan, W, Doody, RS, Quinn, J, and Luo, S. "Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data." Journal of Alzheimer’s Disease 58 (2017): 361-371. Open Access Copy
  - Li, K, Furr-Stimming, E, Paulsen, JS, and Luo, S. "Dynamic prediction of motor diagnosis in Huntington's disease using a joint modeling approach." Journal of Huntington’s Disease 6 (2017): 127-37. Open Access Copy
  - Li, K, and Luo, S. "Dynamic predictions in Bayesian functional joint models for longitudinal and time-to-event data: an application to Alzheimer’s disease." Statistical Methods in Medical Research OnlineFirst (2017). (Academic Article) Open Access Copy
  - Rafferty, MR, Schmidt, PN, Luo, ST, Li, K, Marras, C, Davis, TL, Guttman, M, Cubillos, F, Simuni, T, and all NPF-QII Investigators, . "Regular Exercise, Quality of Life, and Mobility in Parkinson's Disease: A Longitudinal Analysis of National Parkinson Foundation Quality Improvement Initiative Data." Journal of Parkinson'S Disease 7, no. 1 (January 2017): 193-202. Full Text Open Access Copy
  - Vidoni, M, Gabriel, KP, Luo, S, Simonsick, EM, and Day, RS. "Vitamin B12 and homocysteine associations with gait speed in older adults." Journal of Nutrition, Health, and Aging OnlineFirst (2017). (Academic Article) Open Access Copy
  - Vidoni, ML, Pettee Gabriel, K, Luo, ST, Simonsick, EM, and Day, RS. "Vitamin B12 and Homocysteine Associations with Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging." The journal of nutrition, health & aging 21, no. 10 (January 2017): 1321-1328. Full Text
  - Wang, J, Luo, S, and Li, L. "Dynamic prediction for multiple repeated measures and event time data: An application to Parkinson’s disease." Annals of Applied Statistics OnlineFirst (2017). (Academic Article) Open Access Copy
  - Yu, R-L, Wu, R-M, Chan, AYY, Mok, V, Wu, Y-R, Tilley, BC, Luo, S, Wang, L, LaPelle, NR, Stebbins, GT, and Goetz, CG. "Cross-Cultural Differences of the Non-Motor Symptoms Studied by the Traditional Chinese Version of the International Parkinson and Movement Disorder Society- Unified Parkinson's Disease Rating Scale." Movement disorders clinical practice 4, no. 1 (January 2017): 68-77. Full Text Open Access Copy
  - Goetz, CG, Liu, Y, Stebbins, GT, Wang, L, Tilley, BC, Teresi, JA, Merkitch, D, and Luo, S. "Gender-, age-, and race/ethnicity-based differential item functioning analysis of the movement disorder society-sponsored revision of the Unified Parkinson's disease rating scale." Movement Disorders : Official Journal of the Movement Disorder Society 31, no. 12 (December 2016): 1865-1873. Full Text Open Access Copy
  - Benoit, JS, Chan, W, Luo, S, Yeh, H-W, and Doody, R. "A hidden Markov model approach to analyze longitudinal ternary outcomes when some observed states are possibly misclassified." Statistics in medicine 35, no. 9 (April 2016): 1549-1557. Full Text Open Access Copy
  - Brown, AL, Poston, WSC, Jahnke, SA, Keith Haddock, C, Luo, S, Delclos, GL, and Sue, DR. "Weight loss advice and prospective weight change among overweight firefighters." International Journal of Occupational and Environmental Health 22 (2016): 233-9. (Academic Article) Open Access Copy
  - Chen, G, and Luo, S. "Robust Bayesian hierarchical model using normal/independent distributions." Biometrical Journal 58 (2016): 831-51. (Academic Article) Open Access Copy
  - Csencsits-Smith, K, Suescun, J, Li, K, Luo, S, Bick, DL, and Schiess, M. "Serum Lymphocyte-Associated Cytokine Concentrations Change More Rapidly over Time in Multiple System Atrophy Compared to Parkinson Disease." Neuroimmunomodulation 23, no. 5-6 (January 2016): 301-308. Full Text Open Access Copy
  - He, B, and Luo, S. "Joint modeling of multivariate longitudinal measurements and survival data with applications to Parkinson's disease." Statistical Methods in Medical Research 25 (2016): 1346-58. Open Access Copy
  - Luo, S, Chan, W, Detry, MA, M, PJ, and Doody, RS. "Binomial regression with a misclassified covariate and outcome." Statistical Methods in Medical Research 25 (2016): 101-17. (Academic Article) Open Access Copy
  - Luo, S, Lawson, AB, He, B, Elm, JJ, and Tilley, BC. "Bayesian multiple imputation for missing multivariate longitudinal data from a Parkinson’s disease clinical trial." Statistical Methods in Medical Research 25 (2016): 821-37. (Academic Article) Open Access Copy
  - Su, X, and Luo, S. "Analysis of censored longitudinal data with skewness and a terminal event." Communications in Statistics-Simulation and Computation OnlineFirst (2016). (Academic Article) Open Access Copy
  - Wang, J, and Luo, S. "Augmented Beta rectangular regression models: A Bayesian perspective." Biometrical journal. Biometrische Zeitschrift 58, no. 1 (January 2016): 206-221. Full Text Open Access Copy
  - Lazaridis, C, Yang, M, DeSantis, SM, Luo, ST, and Robertson, CS. "Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury." Journal of Critical Care 30, no. 6 (December 2015): 1258-1262. Full Text Open Access Copy
  - "Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial." The Lancet. Neurology 14, no. 8 (August 2015): 795-803. Full Text Open Access Copy
  - Kieburtz, K, Tilley, BC, Elm, JJ, Babcock, D, Hauser, R, Ross, GW, Augustine, AH, Augustine, EU, Aminoff, MJ, Bodis-Wollner, IG, Boyd, J, Cambi, F, Chou, K, Christine, CW, Cines, M, Dahodwala, N, Derwent, L, Dewey, RB, Hawthorne, K, Houghton, DJ, Kamp, C, Leehey, M, Lew, MF, Liang, GSL, Luo, ST, Mari, Z, Morgan, JC, Parashos, S, Pérez, A, Petrovitch, H, Rajan, S, Reichwein, S, Roth, JT, Schneider, JS, Shannon, KM, Simon, DK, Simuni, T, Singer, C, Sudarsky, L, Tanner, CM, Umeh, CC, Williams, K, and Wills, A-M. "Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial." Jama 313, no. 6 (February 2015): 584-593. Full Text Open Access Copy
  - Bega, D, Luo, S, Fernandez, H, Chou, K, Aminoff, M, Parashos, S, Walker, H, Russell, DS, Christine, CW, Dhall, R, and others, . "Impact of depression on progression of impairment and disability in early Parkinson’s disease." Movement Disorders Clinical Practice 2 (2015): 371-8. Open Access Copy
  - Brown, AL, Poston, WSC, Jahnke, SA, Haddock, C, Luo, S, Delclos, GL, and Day, RS. "Weight advice associated with male firefighter weight perception and behavior." American Journal of Preventive Medicine 49 (2015): 589-93. (Academic Article) Open Access Copy
  - Chen, Y, Chu, H, Luo, S, Nie, L, and Chen, S. "Bayesian analysis on meta-analysis of case-control studies accounting for within-study correlation." Statistical Methods in Medical Research 24 (2015): 836-55. (Academic Article) Open Access Copy
  - Goetz, CG, Luo, S, Wang, L, Tilley, BC, LaPelle, NR, and Stebbins, GT. "Handling missing values in the MDS-UPDRS." Movement Disorders 30 (2015): 1632-8. (Academic Article) Open Access Copy
  - Luo, S, Su, X, Yi, M, and Hunt, KK. "Simultaneous inference of a misclassified outcome and competing risks failure time data." Journal of Applied Statistics 42 (2015): 1080-90. (Academic Article) Open Access Copy
  - Wang, J, and Luo, S. "Bayesian multivariate augmented Beta rectangular regression models for patient-reported outcomes and survival data." Statistical Methods in Medical Research OnlineFirst (2015). (Academic Article) Open Access Copy
  - Zhu, H, Luo, S, and DeSantis, S. "Zero-inflated Poisson and negative binomial models for longitudinal measures with heterogeneous random effects." Statistical Methods in Medical Research OnlineFirst (2015). (Academic Article) Open Access Copy
  - Luo, S, and Wang, J. "Bayesian hierarchical model for multiple repeated measures and survival data: an application to Parkinson's disease." Statistics in Medicine 33, no. 24 (October 2014): 4279-4291. Full Text Open Access Copy
  - Chen, Y, Luo, S, Chu, H, Su, X, and Nie, L. "An Empirical Bayes Method for Multivariate Meta-analysis with an Application in Clinical Trials." Communications in Statistics: Theory and Methods 43, no. 16 (July 2014): 3536-3551. Full Text Open Access Copy
  - Luo, S, Su, X, DeSantis, SM, Huang, X, Yi, M, and Hunt, KK. "Joint model for a diagnostic test without a gold standard in the presence of a dependent terminal event." Statistics in Medicine 33, no. 15 (July 2014): 2554-2566. Full Text Open Access Copy
  - Parashos, SA, Luo, S, Biglan, KM, Bodis-Wollner, I, He, B, Liang, GS, Ross, GW, Tilley, BC, Shulman, LM, and NET-PD Investigators, . "Measuring disease progression in early Parkinson disease: the National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience." Jama Neurology 71, no. 6 (June 2014): 710-716. Full Text Open Access Copy
  - Luo, S. "A Bayesian approach to joint analysis of multivariate longitudinal data and parametric accelerated failure time." Statistics in Medicine 33, no. 4 (February 2014): 580-594. Full Text Open Access Copy
  - Cubo, E, Goetz, CG, Stebbins, GT, LaPelle, NR, Tilley, BC, Wang, L, and Luo, S. "Independent Spanish validation of the Unified Dyskinesia rating scale." Movement Disorders Clinical Practice 1 (2014): 213-8. (Academic Article) Open Access Copy
  - Goetz, CG, Stebbins, GT, Wang, L, LaPelle, NR, Luo, S, and Tilley, BC. "MDS-sponsored scale translation program: process, format, and clinimetric testing plan for the MDS-UPDRS and UDysRS." Movement Disorders Clinical Practice 1 (2014): 97-101. (Academic Article) Open Access Copy
  - Kashihara, K, Tomoyoshi, T, Mizuno, Y, Kikuchi, S, Kuno, S, Hasegawa, K, Hattori, N, Mochizuki, H, Mori, H, Murata, M, Nomoto, M, Takahashi, R, Takeda, A, Tsuboi, Y, Ugawa, Y, Yamanmoto, M, Yokochi, F, Yoshii, F, Stebbins, GT, Tilley, BC, Luo, S, Wang, L, LaPelle, NR, and Goetz, CG. "Official Japanese version of the Movement Disorder Society-unified Parkinson's disease rating scale: validation against the original English version." Movement Disorders Clinical Practice 1 (2014): 200-12. Open Access Copy
  - Luo, S, Chen, Y, Su, X, and Chu, H. "mmeta: An R Package for Multivariate Meta-Analysis." Journal of Statistical Software 56, no. 11 (January 2014): 11-null. Open Access Copy
  - Byun, J, Lai, D, Luo, S, Risser, J, Tung, B, and Hardy, RJ. "A hybrid method in combining treatment effects from matched and unmatched studies." Statistics in Medicine 32, no. 28 (December 2013): 4924-4937. Full Text Open Access Copy
  - Luo, S. "Joint analysis of stochastic processes with application to smoking patterns and insomnia." Statistics in Medicine 32, no. 29 (December 2013): 5133-5144. Full Text Open Access Copy
  - Luo, S, Ma, J, and Kieburtz, KD. "Robust Bayesian inference for multivariate longitudinal data by using normal/independent distributions." Statistics in Medicine 32, no. 22 (September 2013): 3812-3828. Full Text Open Access Copy
  - Park, M, Luo, S, Kwon, J, Stock, TH, Delclos, G, Kim, H, and Yun-Chul, H. "Effects of Air Pollution on Asthma Hospitalization Rates in Different Age Groups in Metropolitan Cities of Korea." Air Quality, Atmosphere, & Health 6, no. 3 (September 2013). Full Text Open Access Copy
  - Simuni, T, Luo, ST, Chou, KL, Fernandez, H, He, B, and Parashos, S. "Rankin scale as a potential measure of global disability in early Parkinson's disease." Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 20, no. 9 (September 2013): 1200-1203. Full Text Open Access Copy
  - Luo, S, Yi, M, Huang, X, and Hunt, KK. "A Bayesian model for misclassified binary outcomes and correlated survival data with applications to breast cancer." Statistics in Medicine 32, no. 13 (June 2013): 2320-2334. Full Text Open Access Copy
  - Chen, Y, Luo, S, Chu, H, and Wei, P. "Bayesian inference on risk differences: an application to multivariate meta-analysis of adverse events in clinical trials." Statistics in Biopharmaceutical Research 5, no. 2 (May 2013): 142-155. Full Text Open Access Copy
  - Luo, S, Ma, J, and Kieburtz, KD. "Robust Bayesian inference for multivariate longitudinal data using normal/independent distributions." (2013). Open Access Copy
  - Elm, JJ, and NINDS NET-PD Investigators, . "Design innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson's Disease Long-Term Study-1." Movement Disorders : Official Journal of the Movement Disorder Society 27, no. 12 (October 2012): 1513-1521. Full Text Open Access Copy
  - Yi, M, Meric-Bernstam, F, Kuerer, HM, Mittendorf, EA, Bedrosian, I, Lucci, A, Hwang, RF, Crow, JR, Luo, S, and Hunt, KK. "Validation of a Nomogram for Predicting Risk of Local Recurrence for Ductal Carcinoma In Situ Reply." Journal of Clinical Oncology 30, no. 25 (September 1, 2012): 3144-3145. (Letter) Full Text Link to Item
  - Yi, M, Meric-Bernstam, F, Kuerer, HM, Mittendorf, EA, Bedrosian, I, Lucci, A, Hwang, RF, Crow, JR, Luo, S, and Hunt, KK. "Evaluation of a breast cancer nomogram for predicting risk of ipsilateral breast tumor recurrences in patients with ductal carcinoma in situ after local excision." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 30, no. 6 (February 2012): 600-607. Full Text Open Access Copy
  - Chen, Y, and Luo, S. "A few remarks on 'Statistical distribution of the difference of two proportions' by Nadarajah and Kotz, Statistics in Medicine 2007; 26(18):3518-3523." Statistics in Medicine 30, no. 15 (July 2011): 1913-1915. (Letter) Full Text
  - Yi, M, Buchholz, TA, Meric-Bernstam, F, Bedrosian, I, Hwang, RF, Ross, MI, Kuerer, HM, Luo, S, Gonzalez-Angulo, AM, Buzdar, AU, Symmans, WF, Feig, BW, Lucci, A, Huang, EH, and Hunt, KK. "Classification of ipsilateral breast tumor recurrences after breast conservation therapy can predict patient prognosis and facilitate treatment planning." Annals of Surgery 253, no. 3 (March 2011): 572-579. Full Text Open Access Copy
  - Crainiceanu, C, Caffo, B, Luo, S, and Zipunnikov, V. "Population value decomposition, a framework for the analysis of image populations." (2011). Open Access Copy
  - Crainiceanu, CM, Caffo, BS, Luo, S, and Zipunnikov, V. "Population value decomposition, a framework for the analysis of image populations." Journal of the American Statistical Association 106 (2011): 775-90. (Academic Article) Open Access Copy
  - Yi, M, Mittendorf, EA, Cormier, JN, Buchholz, TA, Bilimoria, K, Sahin, AA, Hortobagyi, GN, Gonzalez-Angulo, AM, Luo, S, Buzdar, AU, and others, . "Novel staging system for predicting disease-specific survival in patients with breast cancer treated with surgery as the first intervention: time to modify the current American Joint Committee on Cancer staging system." Journal of Clinical Oncology 29 (2011): 4654-61. (Academic Article) Open Access Copy
  - Luo, S, Mukherjee, B, Chen, J, and Chatterjee, N. "Shrinkage estimation for robust and efficient screening of single-SNP association from case-control genome-wide association studies." Genetic Epidemiology 33, no. 8 (December 2009): 740-750. Full Text Open Access Copy
  - Chatterjee, N, Chen, Y-H, Luo, S, and Carroll, RJ. "Analysis of Case-Control Association Studies: SNPs, Imputation and Haplotypes." Statistical Science : a Review Journal of the Institute of Mathematical Statistics 24, no. 4 (November 2009): 489-502. Full Text Open Access Copy
  - Luo, S, Crainiceanu, CM, Louis, TA, and Chatterjee, N. "Bayesian inference for smoking cessation with a latent cure state." Biometrics 65, no. 3 (September 2009): 970-978. Full Text Open Access Copy
  - Anderson, WF, Luo, S, Chatterjee, N, Rosenberg, PS, Matsuno, RK, Goodman, MT, Hernandez, BY, Reichman, M, Dolled-Filhart, MP, O'Regan, RM, Garcia-Closas, M, Perou, CM, Jatoi, I, Cartun, RW, and Sherman, ME. "Human epidermal growth factor receptor-2 and estrogen receptor expression, a demonstration project using the residual tissue repository of the Surveillance, Epidemiology, and End Results (SEER) program." Breast Cancer Research and Treatment 113, no. 1 (January 2009): 189-196. Full Text Open Access Copy
  - Luo, S, Crainiceanu, CM, Louis, TA, and Chatterjee, N. "Analysis of Smoking Cessation Patterns Using a Stochastic Mixed-Effects Model With a Latent Cured State." Journal of the American Statistical Association 103, no. 483 (September 2008): 1002-1013. Full Text Open Access Copy
- Conference Papers
  - Mao, R, Li, K, Luo, S, Turner, M, Cai, JQ, Blazer, D, and Zhao, H. "Effectiveness of Adjuvant Chemotherapy for Patients with Poorly Differentiated Colorectal Neuroendocrine Carcinomas: A Study of the National Cancer Database." 16th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease. Barcelona, SPAIN. March 6, 2019 - March 8, 2019.: KARGER, January 1, 2019. Link to Item
  - Mao, R, Luo, S, Turner, M, Cai, JQ, Zhao, H, and Blazer, D. "Lymph Node Dissection Does Not Improve Survival in Patients with Pancreatic Neuroendocrine Tumors: A Study of the National Cancer Database." 16th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease. Barcelona, SPAIN. March 6, 2019 - March 8, 2019.: KARGER, January 1, 2019. Link to Item
  - Goetz, C, Luo, S, and Stebbins, G. "Item Response Theory Analysis of the Unified Dyskinesia Rating Scale Items." 70th Annual Meeting of the American-Academy-of-Neurology (AAN). Los Angeles, CA. April 21, 2018 - April 27, 2018.: LIPPINCOTT WILLIAMS & WILKINS, April 10, 2018. Link to Item
  - Yi, M, Mittendorf, EA, Buchholz, TA, Sahin, AA, Kuerer, HM, Luo, S, Bilimoria, KY, Crow, J, Cormier, JN, Gonzalez-Angulo, AM, Buzdar, A, Hortobagyi, GN, and Hunt, K. "A novel staging system for disease-specific survival in patients with breast cancer treated with surgery as the first intervention." : American Society of Clinical Oncology (ASCO), September 20, 2011. Full Text
Teaching & Mentoring
Recent Courses
- BIOSTAT 714: Categorical Data Analysis 2019
Advising & Mentoring
- Primary PhD dissertation advisor
  1. Min Yi, doctoral in Biostatistics, graduated in Spring 2011, dissertation title: "Bayesian and survival model for tumor relapse status and disease-specific survival, with applications to breast cancer". Current position: Senior Biostatistician at MD Anderson Cancer Center.
  2. Geng Chen, doctoral in Biostatistics, graduated in Fall 2014, dissertation title: "Bayesian inference for multivariate longitudinal data analysis using robust distributions". Current position: Senior biostatistician at GlaxoSmithKline.
  3. Huirong Zhu, doctoral candidate in Biostatistics, dissertation defense occurred on November 5, 2015, dissertation title: "Two-part mixture models for zero-inflated heterogeneous measurements and time to event data", co-advise with Stacia DeSantis, PhD. Current position: Biostatistician at Texas Children Hospital.
  4. Li-An Lin, doctoral candidate in Biostatistics, dissertation defense occurred on November 19, 2015, dissertation title: "Bayesian analysis of multi-type recurrent events with dependent termination". Current position: Senior biostatistician at Merck.
  5. Jue Wang, doctoral candidate in Biostatistics, dissertation defense occurred on May 19, 2016, dissertation title: "Dynamic predictions from joint models for multivariate longitudinal measurements and event time data". Current position: Senior biostatistician at Genentech.
  6. Ming Yang, doctoral candidate in Biostatistics, dissertation defense occurred on November 29, 2016, dissertation title: "Bayesian quantile regression joint models: inference and dynamic predictions", co-advise with Stacia DeSantis, PhD. Current position: Senior biostatistician at Genentech.
  7. Kan Li, doctoral candidate in Biostatistics, dissertation defense occurred on Feb 26, 2018, dissertation title: "Functional joint models for longitudinal and time-to-event data", Current position: Senior biostatistician at Merck.
  8. Jun Zhang, doctoral candidate in Biostatistics, dissertation defense occurred on November 6, 2018, dissertation title: "Bayesian semi-parametric joint modeling for Parkinson's disease progression, competing failure times and missing data", Current position: Senior biostatistician at Blue Cross Blue Shield.
  9. Xuehan Ren, doctoral candidate in Biostatistics, proposal defense occurred on April 27, 2017, dissertation title: "Dynamic prediction of recurrent cardiovascular events".
  PhD dissertation committee
  1. Lin Huo, doctoral in Biostatistics, graduated in Spring 2011, dissertation title: "Bayesian adaptive design for early phase drug-combination clinical trials".
  2. Yunfei Wang, doctoral in Biostatistics, graduated in Spring 2012, dissertation title: "A simulation study using the hybrid statistics and the meta-analysis t-test for data with matched and unmatched subjects in the interim analysis of clinical trials".
  3. Jin Young Byun, doctoral in Biostatistics, graduated in Spring 2012, dissertation title: "A hybrid method in combining treatment effects from matched and unmatched studies".
  4. Rui Xia, doctoral in Biostatistics, graduated in year 2014, dissertation title: "A likelihood-based statistical method to detect DNA aberrations in SNP array data of tumor samples with very high normal cell contamination using haplotype structure derived from population genotypes".
  5. Austin Brown, doctoral in Epidemiology, graduated in Spring 2014, dissertation title: "Healthcase professional weight loss advice, diet, physical activity and obesity in the fire service".
  6. Julia Benoit, doctoral in Biostatistics, graduated in Spring 2014, dissertation title: "A hidden Markov model approach to analyze longitudinal ternary outcome subject to possible misclassification".
  7. Michele Vidoni, doctoral student in Epidemiology, graduated in Spring 2016, dissertation title: "Vitamin B12 and homocysteine associations with physical function measures in older adults, data from the Baltimore longitudinal study of aging".
  8. Yi-Ju Chiang, doctoral student in Biostatistics, dissertation proposal defense occured on August 18, 2016, dissertation title: "Bivariate longitudinal logistic models with misclassified covariates and outcomes".
  Primary MS thesis advisor
  1. Eunji Jo, master student in Biostatistics, graduated in Fall 2009, thesis title: "Comparison of Bayesian and frequentist approaches in clinical outcomes between hospitals".
  2. Minjeong Park, master student in Biostatistics, graduated in Spring 2010, thesis title: "Effects of air pollution on asthma hospitalization rates in different age groups in metropolitan cities of Korea".
  3. Xiao Su, master in Biostatistics, graduated in May 2012, thesis title: "Bayesian estimation of multilevel item response model with missing data".
  MS students thesis committee
  1. Farzana Noor Bindu, Master Student in Biostatistics, graduated in Spring 2012, thesis title: "Performance of classifying diabetes and diagnostic threshold for diabetes among the Mexican American border community".
  2. Jin Li, Master Student in Biostatistics, graduated in Fall 2011, thesis title: "Nonlinear dimension reduction in pathway-based genome-wide association analysis".
  3. Huandong Sun, Master Student in Biostatistics, graduated in Spring 2012, thesis title: "A computerized statistical framework for coalescent analysis".
Teaching Activities
- Course taught at Department of Biostatistics, University of Texas School of Public Health
  1. Statistical Computing, PH 1998, Spring 2009, lead instructor, 100% responsibility.
  2. Bayesian Data Analysis, PH 1998, Fall 2009, lead instructor, 100% responsibility.
  3. Statistical Computing, PH 1998, Fall 2010, lead instructor, 100% responsibility.
  4. Bayesian Data Analysis, PH 1998, Spring 2011, lead instructor, 100% responsibility.
  5. Statistical Computing, PH 1998, Fall 2011, lead instructor, 100% responsibility.
  6. Statistical Computing, PH 1930, Fall 2012, lead instructor, 100% responsibility.
  7. Bayesian Data Analysis, PH 1965, Spring 2013, lead instructor, 100% responsibility.
  8. Statistical Computing, PH 1930, Fall 2013, lead instructor, 100% responsibility.
  9. Statistical Computing, PH 1930, Fall 2014, lead instructor, 100% responsibility.
  10. Statistical Methods in Correlated Outcomes, PH 1918, Spring 2016, lead instructor, 100% responsibility.
  11. Statistical Computing, PH 1930, Fall 2016, lead instructor, 100% responsibility.
  12. Categorical Data Analysis, BIOSTAT 714, lead instructor, 100% responsibility.
Scholarly, Clinical, & Service Activities
Service to the Profession

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

In the News

Awards & Honors

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Conference Papers

Recent Courses

Advising & Mentoring

Teaching Activities

Service to the Profession