Skip to main content

Sheng Sun

Associate Research Professor in Molecular Genetics and Microbiology
Molecular Genetics and Microbiology
213 Research Drive, CARL Building Room 320, Duke University Medical Center, Durham, NC 27710

Current Appointments & Affiliations


Associate Research Professor in Molecular Genetics and Microbiology · 2023 - Present Molecular Genetics and Microbiology, Basic Science Departments

Recent Publications


Unisexual reproduction in the global human fungal pathogen Cryptococcus neoformans.

Journal Article Proc Natl Acad Sci U S A · October 21, 2025 The human fungal pathogen Cryptococcus species complex (encompassing Cryptococcus neoformans, Cryptococcus deneoformans, and the Cryptococcus gattii species complexes) exhibits diversity in sexual reproduction, including α-a mating, pseudosexual reproducti ... Full text Link to item Cite

Meiosis-specific genes play roles in ploidy reduction in Cryptococcus neoformans titan cells.

Journal Article bioRxiv · September 18, 2025 Cryptococcus neoformans is a fungal pathogen of humans that causes life-threatening meningoencephalitis. During infection, enlarged, polyploid titan cells are produced that promote survival, evade immune cells, and generate diverse progeny. These titan cel ... Full text Link to item Cite
View All Publications

Recent Grants


Calcineurin signaling cascades governing Cryptococcus virulence

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028

The Genetic Basis of Virulence in Cryptococcus Neoformans

ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2017 - 2028

RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

View All Grants

Education, Training & Certifications


McMaster University (Canada) · 2009 Ph.D.