Current Duke Appointments & Affiliations
Professor of Medicine
·
2024 - Present
Medicine, Medical Oncology,
Medicine
Member of the Duke Cancer Institute
·
2004 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Scholarly Works
Circulating Tumor DNA as a Novel Prognostic Biomarker of Therapeutic Efficacy in Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion.
Journal article Ann Surg Oncol · October 2025 BACKGROUND: Hepatic arterial infusion (HAI) chemotherapy is an expanding treatment for patients with unresectable colorectal liver metastases (uCRLM). This study examined circulating tumor DNA (ctDNA) as a novel biomarker to prognosticate oncologic outcome ... Full text Link to item CiteAdjuvant Cytotoxic Chemotherapy may not be Associated with a Survival Advantage for Resected Intrahepatic Cholangiocarcinoma.
Journal article Ann Surg Oncol · April 2025 BACKGROUND: Randomized data suggest improved survival with adjuvant chemotherapy for biliary tract cancers; however, subset analyses of intrahepatic cholangiocarcinoma (IHC) show limited survival benefit. This study evaluated the impact of adjuvant chemoth ... Full text Link to item CiteTrends in Receipt of Adjuvant Chemotherapy and its Impact on Survival in Resected Biliary Tract Cancers.
Journal article Ann Surg Oncol · August 2023 BACKGROUND: Resection remains the cornerstone of curative-intent treatment for biliary tract cancers (BTCs). However, recent randomized data also support a role for adjuvant chemotherapy (AC). This study aimed to characterize trends in the use of AC and su ... Full text Link to item CiteRecent Grants
ABL kinase signaling networks regulate Transcription-Replication Collisions in Small Cell Lung Cancer
ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2026 - 2031Identification and inhibition of the novel downstream effectors of mutant Ras for mutant Ras-driven cancer targeting
ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2031Modeling Minimal Residual Disease in Colorectal Cancer
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2026 - 2028View All Grants
Education
University of North Carolina, Chapel Hill ·
2001
M.D.