Conference2026 IEEE Conference on Artificial Intelligence Cai 2026 · January 1, 2026
This paper presents a comprehensive comparative study of automated detection of hip replacements and fiducial markers in pelvic computed tomography (CT) scans, evaluating rule-based anatomically-constrained methods against modern deep learning techniques. ...
Full textCite
ConferenceLecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics · January 1, 2023
Academic radiation oncology centers have a long history of developing in-house quality assurance (QA) checklists to promote patient safety. These checklists are designed without utilizing formal human-computer interaction methods and are deployed without r ...
Full textCite
ConferenceInt J Radiat Oncol Biol Phys · April 1, 2017
PURPOSE: To evaluate early cardiac single photon computed tomography (SPECT) findings after left breast/chest wall postoperative radiation therapy (RT) in the setting of deep inspiration breath hold (DIBH). METHODS AND MATERIALS: We performed a prospective ...
Full textLink to itemCite
ConferenceInt J Radiat Oncol Biol Phys · August 1, 2016
PURPOSE: To study the risk factors for radiation-induced lung toxicity (RILT) after stereotactic body radiation therapy (SBRT) of the thorax. METHODS AND MATERIALS: Published studies on lung toxicity in patients with early-stage non-small cell lung cancer ...
Full textLink to itemCite
ConferenceMedical Physics · January 1, 2013
Purpose: To examine the effect of PET image reconstruction parameters on baseline and early‐treatment FDG‐PET/CT quantitative imaging. Early‐treatment changes in tumor metabolism in primary tumor and nodes can potentially determine if the patient is respon ...
Full textCite
ConferenceJ Phys Conf Ser · 2013
Deformable 3D dosimeters have potential applications in validating deformable dose mapping algorithms. This study evaluates a novel deformable PRESAGE® dosimeter and its application toward validating the deformable algorithm employed by VelocityAI. The def ...
Full textLink to itemCite
ConferenceJ Phys Conf Ser · 2013
There is significant interest in delivering precisely targeted small-volume radiation treatments, in the pre-clinical setting, to study dose-volume relationships with tumor control and normal tissue damage. In this work we investigate the IGRT targeting ac ...
Full textLink to itemCite
ConferenceMed Phys · June 2012
PURPOSE: To verify that a knowledge-based approach to intensity modulated radiotherapy (IMRT) treatment planning can create clinically acceptable plans of higher or comparable dosimetric quality than prior clinically approved plans. METHODS: Each case in a ...
Full textLink to itemCite
ConferenceMed Phys · June 2012
PURPOSE: In prostate IMRT treatment planning, the variation in patient anatomy makes it difficult to estimate a priori the potentially achievable extent of dose reduction possible to the rectum and bladder. We developed a mutual information-based framework ...
Full textLink to itemCite
ConferenceMedical Physics · January 1, 2012
Purpose: Gaussian smoothing reduces noise in PET images but blurs edges impacting the achievable accuracy in radiotherapy target segmentation. Bilateral filters both provide smoothing while simultaneously preserving edges. We compared the accuracy of four ...
Full textCite
ConferenceMedical Physics · January 1, 2012
Purpose: To compare intrinsic, temporal variability of tumor glucose metabolism versus early treatment‐induced change. This assessment is necessary to use changes in imaging parameters during therapy to properly segregate metabolic responders from non‐resp ...
Full textCite
ConferenceMedical Physics · January 1, 2012
Purpose: To investigate the necessity for adaptive radiation therapy (RT) in lung cancer IMRT treatments by quantifying tumor changes during radiotherapy and the associated impact on target, lung and esophagus. Methods: As part of an IRB‐approved lung dose ...
Full textCite
ConferenceMedical Physics · January 1, 2011
Purpose: To commission and characterize a novel small animal irradiator, the XRad225cx from Precision X‐Ray Inc. This system is capable of delivering both square and circular fields ranging in size from 1mm to 40mm. The combination of very small field size ...
Full textCite
ConferenceMedical Physics · January 1, 2011
Purpose: To evaluate the feasibility of using a site‐specific database of prior plans to generate new prostate IMRT plans for cases drawn from an outside institution. Methods: The assembled database consists of 250 retrospective prostate IMRT treatment pla ...
Full textCite
ConferenceMedical Physics · January 1, 2011
Purpose: To investigate the performance improvement of a novel region growing (SRG) and “segmentation‐by‐consensus” (SBC) technique for delineation of lesions in FDG‐PET. Further, the improvement in lesion segmentation using time‐of‐flight (TOF) PET was in ...
Full textCite
ConferenceMedical Physics · January 1, 2011
Functional imaging in radiotherapy has great promise to guide radiation delivery as well as to monitor response to treatment. Normal tissues as well as tumor tissues may be imaged with functional imaging. This talk will discuss positron emission tomography ...
Full textCite
ConferenceMedical Physics · January 1, 2011
Purpose: To assess external validity of a framework, which was previously developed to predict the incidence of radiation‐induced pneumontis in patients following radiotherapy for lung cancer, by testing it on an alternate dataset (other than the one used ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: To compare the dosimetric results and treatment efficiency of intensity modulated arc therapy using RapidArc™ to static‐gantry IMRT plans for conventional fractionation treatment of head‐and‐neck cancer. Materials and Methods: This study evaluated ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: In prostate IMRT treatment planning, the variation in patient anatomy makes it difficult to a priori estimate the maximum extent of dose reduction possible to rectum and bladder. Such an estimation would greatly aid treatment planning by letting c ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: Gantry‐angle dependence of dose measurement for intensity‐modulated arc therapy (IMAT) quality assurance (QA) using a two‐dimensional ion chamber array may be significant. A new device, the gantry angle sensor, has been provided to compensate for ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: Single photon emission computed tomography (SPECT) may be used to guide thoracic radiation therapy planning by reducing the dose to highly‐perfused (i.e.functional) regions of lung. We herein investigate whether it is possible to a priori predict ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: To explore similarities between intensity modulated radiotherapy (IMRT) and intensity modulated arc therapy (IMAT) techniques in the context of the number of multi‐leaf collimator (MLC) segments required to achieve plan objectives, the major facto ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: To determine which dose and non‐dose features of patients undergoing thoracic radiotherapy best predict the incidence of possible lung pneumonitis and to estimate the corresponding risk of developing pneumonitis. Method and Materials: The study em ...
Full textCite
ConferenceMedical Physics · January 1, 2010
Purpose: To investigate the potential of utilizing a knowledge‐base of clinically approved plans to develop semi‐automated IMRT treatment plans for prostate cancer. Method and Materials: We assembled a database of 100 prostate IMRT treatment plans and deve ...
Full textCite
ConferenceMedical Physics · January 1, 2009
Purpose: Binary outcomes (toxicity=1, no‐toxicity=0) are frequently used as inputs to fit parametric models. However, in reality, outcomes span the range in‐between these extremes; binary values are used for lack of more precise quantification. We propose ...
Full textCite
ConferenceMedical Physics · January 1, 2009
Purpose: The purpose of this study is to compare RapidArc plans and conventional IMRT plans for head‐and‐neck cancer treatment involving bilateral nodes. Methods and Materials: This study included 10 locally advanced head‐and‐neck cancer patients. The plan ...
Full textCite
ConferenceMedical Physics · January 1, 2009
Purpose: To develop a patient‐specific quality assurance protocol for RapidArc™ radiotherapy. Method and Materials: Following the commissioning of RapidArc™ treatment delivery, we tested several methods of patient‐specific quality assurance (QA). Ion chamb ...
Full textCite
ConferenceMedical Physics · January 1, 2009
Purpose: To investigate how a real‐time tracking technique, based on implanted transponders, could be effectively integrated into the current process for image‐guided radiation treatment of prostate cancer. Method and Materials: Current prostate IGRT proce ...
Full textCite
ConferenceMedical Physics · January 1, 2009
Purpose: Biological optimization for IMRT planning is typically not clinically utilized, perhaps due to uncertainties associated with normal tissue complication models. Clinically, IMRT planning still relies heavily on dose‐volume constraints. We propose a ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: Combining the results of methodologically different models (decision fusion) has been shown to yield a fused result that more truthfully represents the underlying phenomenon, compared to the individual models. In this work, we study the effect of ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: To predict radiation‐induced cardiac perfusion defects using a fusion model that combines the results of four separate models: feed‐forward neural networks (NNET), self‐organizing maps (SOM), support vector machines (SVM), and multivariate adaptiv ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: Though hyperthermia shows promising features being used with radiation and chemotherapy, it requires accurate spatial power focusing, which leads a workload proportional to square of number of antennas in an applicator. This motivates this investi ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: The IMRT treatment planning optimization process typically follows one, somewhat arbitrary, path, based on the manner in which the planner changes the optimization constraints/weights during planning. Thus, the planner usually never fully understa ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: Using an on‐board cone‐beam CT (CBCT) based statistical margin model to determine whether a prostate center‐of‐mass (COM) based translation correction procedure can significantly reduce the CTV‐to‐PTV margin required for prostate patients who were ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: To quantitatively assess the relationship between intensity‐modulated radiotherapy (IMRT)‐driven sparing of dose to normal tissues located “within” concave targets with (1) heterogeneity in dose delivered to the target and (2) redistribution of do ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: Cancerous cells are infiltrative and can invade neighborhood and/or distant body. While hyperthermia shows promising synergistic effects being used with radiation and/or chemotherapy, current microwave/radiofrequency power focusing techniques only ...
Full textCite
ConferenceMedical Physics · January 1, 2008
Purpose: Hyperthermia is an effective adjuvant modality for treatment of locally advanced cancer. However, focusing heat in the tumor using an external microwave applicator can be difficult, due to electromagnetic wave reflections at tissue interfaces. We ...
Full textCite
ConferenceMedical Physics · January 1, 2007
Purpose: To evaluate the dosimetric improvement of IMRT treatment plans generated with patient‐specific margins compared to uniform margins for prostate cancer patients. Methods and Materials: For 13 prostate cancer patients who underwent IMRT treatment, d ...
Full textCite
ConferenceMedical Physics · January 1, 2007
Purpose: Develop a model that augments the dose‐based parametric Lyman NTCP formulation using non‐parametric decision trees that can additionally account for the influence of non‐dose variables. Apply and test the model to predict Grade 2+ lung radiotherap ...
Full textCite
ConferenceMedical Physics · January 1, 2007
Purpose: Single photon emission computed tomography (SPECT) provides a spatial distribution map of lung perfusion. Previously, an algorithmic methodology was developed using IMRT and SPECT guidance to deliberately divert dose away from higher functioning ( ...
Full textCite
ConferenceMedical Physics · January 1, 2007
Objective: The true dose distribution is subject to change due to organ shifts and also deformations. The goal of this work is to estimate the effect of the elastic organ deformations on the dose distribution for the average prostate IMRT treatment. Method ...
Full textCite
ConferenceMedical Physics · January 1, 2007
Purpose: To build and test a feed‐forward neural network model to predict the occurrence of lung radiation‐induced Grade 2+ pneumonitis. Method and Materials: The database comprised 235 patients with lung cancer treated using radiotherapy (34 diagnosed wit ...
Full textCite
ConferenceMedical Physics · January 1, 2007
Purpose: Radiation pneumonitis (RP) is a major concern for patients receiving radiotherapy for lung cancer. The present study assesses the possibility of using multiple dose‐volume‐histogram (DVH) based metrics to predict the likelihood of grade ⩾ 2 RP. MA ...
Full textCite
ConferenceMedical Physics · January 1, 2006
Purpose: Since radiotherapy treatments only utilize a limited number of beams, it is important that these beams be carefully selected to extract maximum benefit. Here we propose a novel, fast, scheme that selects beam number and orientations for IMRT with ...
Full textCite
ConferenceMedical Physics · January 1, 2006
Purpose: To evaluate the dosimetric consequence of 3D positioning verification for prostate IMRT treatment using CBCT. Method and Materials: Patients in this study were repositioned using 2D orthogonal radiographic images, taken prior to treatment to match ...
Full textCite
ConferenceMedical Physics · January 1, 2006
Purpose: A novel imaging based model is proposed to describe the stochastic nature of the shape and location of a volume of interest (VOI). Based on the VOIs in sequential patient images, the model can predict the probability that a specific point will bel ...
Full textCite
ConferenceMedical Physics · January 1, 2006
Purpose: To implement a clinical tool for off‐line review of Cone‐Beam Computed Tomography (CBCT) based 3D target verification and localization. Methods and Materials: An in‐house 3D target localization and verification tool is being developed to allow phy ...
Full textCite
ConferenceMedical Physics · January 1, 2006
Purpose: Single photon emission computed tomography (SPECT) provides a map of the spatial distribution of lung perfusion. Thus, SPECT guidance can be used to deliberately divert dose away from higher functioning lung, thereby potentially reducing lung toxi ...
Full textCite
ConferenceMedical Physics · January 1, 2005
Purpose: To quantify the degree of normal organ motion due to the respiratory and cardiac cycles. Better definition of such motion may be useful in defining field margins and in assessing the utility of gating technologies. Method and Materials: Four healt ...
Full textCite
ConferenceASME International Mechanical Engineering Congress and Exposition Proceedings Imece · January 1, 2000
Essential to the success of optimized thermal treatment duringhyperthermia is accurate modeling. Advection of energy due to bloodperfusion significantly perturbs the temperature and without accurateestimates of the magnitude of the local tissue blood perfu ...
Full textCite
ConferenceASME International Mechanical Engineering Congress and Exposition Proceedings Imece · January 1, 1999
It has been shown that the fractal dimension of 2D microvascular networks can discriminate between normal vs. tumor tissue (Gazit et al., 1995, 1997). We have determined the fractal characteristics of five 3D microvascular networks and conclude on the corr ...
Full textCite
