Scholars@Duke

• Recognition
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  In the News

  • DEC 12, 2019

    CT dose calculations can be both quick and accurate
• Research
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  Selected Grants

  • Precision Cardiac CT: Development of a Computational Platform for Optimizing Imaging awarded by National Institutes of Health 2017 - 2022
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Sharma, Shobhit, Anuj Kapadia, Justin Brown, William Paul Segars, Wesley Bolch, and Ehsan Samei. “A GPU-accelerated framework for individualized estimation of organ doses in digital tomosynthesis.” Medical Physics, December 13, 2021. https://doi.org/10.1002/mp.15400.
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    • Jadick, Giavanna, Ehsan Abadi, Brian Harrawood, Shobhit Sharma, W Paul Segars, and Ehsan Samei. “A scanner-specific framework for simulating CT images with tube current modulation.” Phys Med Biol 66, no. 18 (September 13, 2021). https://doi.org/10.1088/1361-6560/ac2269.
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    • Fu, Wanyi, Shobhit Sharma, Ehsan Abadi, Alexandros-Stavros Iliopoulos, Qi Wang, Joseph Y. Lo, Xiaobai Sun, William P. Segars, and Ehsan Samei. “iPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and Its Application to CT Organ Dosimetry.” Ieee J Biomed Health Inform 25, no. 8 (August 2021): 3061–72. https://doi.org/10.1109/JBHI.2021.3063080.
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    • Sharma, Shobhit, Ehsan Abadi, Anuj Kapadia, W Paul Segars, and Ehsan Samei. “A GPU-accelerated framework for rapid estimation of scanner-specific scatter in CT for virtual imaging trials.” Phys Med Biol 66, no. 7 (March 23, 2021). https://doi.org/10.1088/1361-6560/abeb32.
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    • Abadi, Ehsan, William P. Segars, Brian Harrawood, Shobhit Sharma, Anuj Kapadia, and Ehsan Samei. “Virtual clinical trial for quantifying the effects of beam collimation and pitch on image quality in computed tomography.” J Med Imaging (Bellingham) 7, no. 4 (July 2020): 042806. https://doi.org/10.1117/1.JMI.7.4.042806.
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    • Sharma, Shobhit, Anuj Kapadia, Wanyi Fu, Ehsan Abadi, W Paul Segars, and Ehsan Samei. “A real-time Monte Carlo tool for individualized dose estimations in clinical CT.” Phys Med Biol 64, no. 21 (November 4, 2019): 215020. https://doi.org/10.1088/1361-6560/ab467f.
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    • Hoye, Jocelyn, Shobhit Sharma, Yakun Zhang, Wanyi Fu, Francesco Ria, Anuj Kapadia, W Paul Segars, Joshua Wilson, and Ehsan Samei. “Organ doses from CT localizer radiographs: Development, validation, and application of a Monte Carlo estimation technique.” Med Phys 46, no. 11 (November 2019): 5262–72. https://doi.org/10.1002/mp.13781.
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    • Abadi, Ehsan, Brian Harrawood, Jayasai R. Rajagopal, Shobhit Sharma, Anuj Kapadia, William Paul Segars, Karl Stierstorfer, Martin Sedlmair, Elizabeth Jones, and Ehsan Samei. “Development of a scanner-specific simulation framework for photon-counting computed tomography.” Biomed Phys Eng Express 5, no. 5 (August 2019). https://doi.org/10.1088/2057-1976/ab37e9.
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    • Abadi, Ehsan, Brian Harrawood, Shobhit Sharma, Anuj Kapadia, William P. Segars, and Ehsan Samei. “DukeSim: A Realistic, Rapid, and Scanner-Specific Simulation Framework in Computed Tomography.” Ieee Trans Med Imaging 38, no. 6 (June 2019): 1457–65. https://doi.org/10.1109/TMI.2018.2886530.
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  • Conference Papers

    • Fu, W., P. W. Segars, S. Sharma, J. Y. Lo, and E. Samei. “IPhantom: An automated framework in generating personalized computational phantoms for organ-based radiation dosimetry.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2582238.
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    • Jadick, G., E. Abadi, B. Harrawood, S. Sharma, W. P. Segars, and E. Samei. “A framework to simulate ct images with tube current modulation.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2580983.
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    • Abadi, Ehsan, William Segars, Shobit Sharma, Francesco Ria, Hamid Chalian, and Ehsan Samei. “Virtual Imaging Trials for Novel Coronavirus Disease (COVID-19),” 2020.
    • Abadi, Ehsan, Brian Harrawood, Jayasai Rajagopal, Shobhit Sharma, Anuj Kapadia, Martin Sedlmair, Juan Carlos Ramirez-Giraldo, Karl Stierstorfer, W Paul Segars, and Ehsan Samei. “A framework for realistic virtual clinical trials in photon counting computed tomography.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:109484F-109484F, 2019.
    • Abadi, Ehsan, W Paul Segars, Brian Harrawood, Shobhit Sharma, Thomas Sauer, Anuj Kapadia, and Ehsan Samei. “Trade-off between spatial details and motion artifact in multi-detector CT: A virtual clinical trial with 4D textured human models.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:109482R-109482R, 2019.
    • Fu, Wanyi, Shobhit Sharma, Taylor Smith, Rui Hou, Ehsan Abadi, Vignesh Selvakumaran, Ruixiang Tang, et al. “Multi-organ segmentation in clinical-computed tomography for patient-specific image quality and dose metrology.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:1094829–1094829, 2019.
    • Sharma, Shobhit, Ehsan Abadi, Anuj Kapadia, W Paul Segars, and Ehsan Samei. “A comprehensive GPU-based framework for scatter estimation in single source, dual source, and photon-counting CT.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:109482V-109482V, 2019.
    • Fenoli, J., S. Sharma, E. Abadi, P. Segars, E. Samei, and A. Kapadia. “Organ Dose Heterogeneity in Chest and Abdominopelvic CT Scans for a Population of Adult and Pediatric Phantoms: A Virtual Clinical Trial Study.” In Medical Physics, 45:E153–E153, 2018.
    • Fu, Wanyi, William P. Segars, Ehsan Abadi, Shobhit Sharma, Anuj J. Kapadia, and Ehsan Samei. “From patient-informed to patient-specific organ dose estimation in clinical computed tomography.” In Medical Imaging 2018: Physics of Medical Imaging, 10573:1057315–1057315, 2018.
    • Sharma, S., E. Abadi, P. Segars, A. Kapadia, and E. Samei. “A Real-Time Monte-Carlo Simulation Technique for Dose and Scatter Estimation in Virtual Clinical Trials for CT Imaging.” In Medical Physics, 45:E689–E689, 2018.
    • Sharma, Shobhit, Anuj Kapadia, Ehsan Abadi, Wanyi Fu, W Paul Segars, and Ehsan Samei. “A rapid GPU-based Monte-Carlo simulation tool for individualized dose estimations in CT.” In Medical Imaging 2018: Physics of Medical Imaging, 10573:105733V-105733V, 2018.
    • Fenoli, J., J. Hoye, S. Sharma, J. Spencer, B. Harrawood, P. Segars, E. Samei, and A. Kapadia. “evaluation of Intra-organ Dose Heterogeneity Using Xcat Phantoms: su-h2-gepd-i-05.” In Medical Physics, 44:2769–2769. Medical Physics, 2017.
• Scholarly, Clinical, & Service Activities
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  Presentations & Appearances

  • Deep Silicon-based Photon Counting CT: A Virtual Clinical Study For Assessing Perceptual Benefits Of Improved Spatial Resolution Across Multiple Anatomies. November 2021  2021
  • Deep Silicon-based Photon Counting CT: Improved Estimation Accuracy Of Radiomics Features For Lung Lesions. November 2021  2021
  • A scanner-specific simulation platform for virtual imaging trials in deep Si-based photon-counting CT. AAPM Annual Meeting. July 2021  2021
  • A comprehensive GPU-based framework for scatter estimation in single source, dual source, and photon-counting CT. SPIE Medical Imaging. February 2019  2019
  • How Much Does Low kV Imaging Increase Skin Radiation Dose in Contrast-Enhanced CT? - A Simulation Study on a Virtual Population of Patient Models. RSNA Annual Meeting. November 2018  2018
  • A Real-Time Monte-Carlo Simulation Technique for Dose and Scatter Estimation in Virtual Clinical Trials for CT Imaging. AAPM Annual Meeting. July 2018  2018
  • A rapid GPU-based Monte Carlo simulation tool for individualized dose estimations in CT. SPIE Medical Imaging. February 2018  2018

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