Skip to main content

Shruti Agashe

Assistant Professor of Neurology
Neurology, Epilepsy and Sleep
Box 90361, Durham, NC 27708-0361
Law School Library, Durham, NC 27708

Overview


My patients have motivated me to be involved in clinical research. My interests spans areas such as identification of biomarkers in epilepsy, pre-surgical evaluation in epilepsy including stereoEEG and drugs/ device trials in epilepsy. Given my background in biomedical engineering, I have a special interest in Neuromodulation including deep brain stimulation, responsive neurostimulation, use of Artificial intelligence/machine learning on EEGs as well as developing novel device therapies for use in epilepsy care.

Current Appointments & Affiliations


Assistant Professor of Neurology · 2023 - Present Neurology, Epilepsy and Sleep, Neurology
Assistant Professor of Neurosurgery · 2025 - Present Neurosurgery, Neurosurgery

Recent Publications


Responsive neurostimulation detections: "Recognizing the unseen".

Journal Article Epileptic Disord · May 24, 2025 BACKGROUND: Closed-loop responsive neurostimulation (RNS) is an established non-resective neuromodulatory therapy for individuals with drug-resistant epilepsy (DRE). RNS systems are typically programmed to detect and respond to predefined seizure onset pat ... Full text Link to item Cite

A Scoping Review of Responsive Neurostimulation in Focal Cortical Dysplasia-Related Epilepsy.

Journal Article Epilepsy & behavior : E&B · May 2025 ObjectiveResponsive Neurostimulation (RNS) is a closed-loop neuromodulation therapy approved for treating drug resistant epilepsy (DRE) with 1 or 2 seizure foci, but its potential utility for treating complex seizure networks, such as in focal cor ... Full text Cite

Focal to bilateral tonic-clonic seizures in newly diagnosed focal epilepsy.

Journal Article Epilepsia · April 2025 Presence of focal to bilateral tonic-clonic seizures (FBTCS) in focal epilepsy is associated with increased morbidity and mortality. Risk factors for FBTCS are poorly understood, and little is known regarding FBTCS recurrence after treatment initiation. Th ... Full text Link to item Cite
View All Publications

Recent Grants


Developing a Neuromodulation System to Improve Sleep Quality in Epilepsy with a Vision for Broader Neuropsychiatric Applications

ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2025 - 2026

View All Grants

Education, Training & Certifications


University of Texas, Medical Branch at Galveston · 2017 M.D.