Sin-Ho Jung

Journal article J Clin Periodontol · January 2002 Featured Publication BACKGROUND: When a binary response is observed on teeth from each subject belonging to 2 or more exposure groups, application of the usual Pearson chi2 tests is invalid, since such responses within the same subject are not independent. Consequently, specia ... Full text Link to item Cite

Accuracy of predicting long-term prostate specific antigen outcome based on early prostate specific antigen recurrence results after radical prostatectomy.

Journal article J Urol · December 2001 Featured Publication PURPOSE: We determined how prostate specific antigen (PSA) doubling time changed with time and whether an early measure of doubling time would accurately predict long-term PSA values and clinical outcome in a cohort of patients followed expectantly after r ... Link to item Cite

Graphical search for two-stage designs for phase II clinical trials.

Journal article Control Clin Trials · August 2001 Featured Publication In a typical two-stage design employed in a phase II cancer clinical trial for efficacy screening, a fixed number of patients are initially enrolled. The trial may be terminated for lack of clinical efficacy of treatment if the observed number of treatment ... Full text Link to item Cite

FDG-PET sensitivity for melanoma lymph node metastases is dependent on tumor volume.

Journal article J Surg Oncol · August 2001 Featured Publication BACKGROUND AND OBJECTIVES: The purpose of this study is to determine the tumor volume threshold for successful positron emission tomography (PET) imaging of melanoma nodal metastases. METHODS: Review of a clinical series of patients who had FDG-PET imaging ... Full text Link to item Cite

Characterization and predictors of prostate specific antigen progression rates after radical retropubic prostatectomy.

Journal article J Urol · September 2000 Featured Publication PURPOSE: Detectable serum prostate specific antigen (PSA) after radical prostatectomy indicates recurrent disease and treatment failure. We characterized PSA recurrence after prostatectomy and identified predictors of rapid PSA progression. MATERIALS AND M ... Full text Link to item Cite

Rank tests for matched survival data.

Journal article Lifetime Data Anal · 1999 Featured Publication In a clinical trial with the time to an event as the outcome of interest, we may randomize a number of matched subjects, such as litters, to different treatments. The number of treatments equals the number of subjects per litter, two in the case of twins. ... Full text Link to item Cite

Neuroendocrine differentiation is an independent prognostic factor in chemotherapy-treated nonsmall cell lung carcinoma.

Journal article Cancer · April 1, 1996 Featured Publication BACKGROUND: Neuroendocrine differentiation can be identified in 10-30% of patients with nonsmall cell lung carcinoma (NSCLC) by immunohistochemical or electron microscopic techniques. However, its clinical significance is not well established. METHODS: Tum ... Full text Link to item Cite

Randomized, surgical adjuvant clinical trial of recombinant interferon alfa-2a in selected patients with malignant melanoma.

Journal article J Clin Oncol · November 1995 Featured Publication PURPOSE: We conducted a randomized prospective trial in selected patients with fully resected high-risk stage I and II malignant melanoma. PATIENTS AND METHODS: Interferon alfa-2a (IFN-alpha 2a) 20 x 10(6) U/m2 was administered three times each week for 12 ... Full text Link to item Cite

A statistic for comparing two correlated markers which are prognostic for time to an event.

Journal article Stat Med · October 30, 1995 Featured Publication A proliferation of biologic markers has led to increased interest in methods for comparing the prognostic value of markers in predicting time to recurrence of or death from disease. This paper proposes a nonparametric test statistic for comparing two conti ... Full text Link to item Cite

A phase II study of paclitaxel and granulocyte colony-stimulating factor in previously untreated patients with extensive-stage small cell lung cancer: a study of the North Central Cancer Treatment Group.

Journal article Semin Oncol · June 1995 Featured Publication In 1994, approximately 34,000 to 43,000 Americans will be diagnosed with small cell lung cancer, and 60% to 70% of these individuals will have extensive-stage disease. The median survival time of patients with extensive-stage small cell lung cancer is 8 to ... Link to item Cite

Randomized trial of cyclophosphamide, methotrexate, and 5-fluorouracil with or without estrogenic recruitment in women with metastatic breast cancer.

Journal article Cancer · May 1, 1994 Featured Publication BACKGROUND: The fraction of breast cancer cells undergoing DNA synthesis at any one time is relatively low, which is problematic because most chemotherapeutic agents are most effective against dividing cells. Estrogens administered in vitro and in vivo can ... Full text Link to item Cite