Sonali Advani | Scholars@Duke

Sonali Advani
Assistant Professor of Medicine

Dr. Advani is an Assistant Professor of Medicine at Duke University School of Medicine and serves as the Co-Medical Director of Duke Infection Control Outreach Network (DICON). In her role, she assists member hospitals in further development and strengthening of their existing infection prevention programs. She also participates as a physician investigator in the research activities of the Duke Center for Antimicrobial Stewardship and Infection Prevention. Prior to joining Duke, Dr. Advani served as the Associate Medical Director for the Yale-New Haven Hospital Epidemiology program. Her main research interests include prevention of catheter-related harm, application of diagnostic stewardship interventions and improving metrics to better align with outcomes. She currently serves on the SHEA Guidelines Committee, IDWeek Mentorship Committee, IDSA Antimicrobial Stewardship Workgroup and Chair of SHEA Journal Club 2020. She has been awarded the K12 Urologic Career Development Award and SHEA Research Scholar Award to continue her UTI related research.

Dr. Advani is leading the COVID-19 response for over 50 network hospitals within DICON. She has helped create and disseminate a library of COVID-19 resources to community hospitals nationwide. She is currently working on expanding these resources to low and middle income countries.

Current Research Interests

My main research interests include prevention of catheter-related harm, application of diagnostic stewardship interventions and improving metrics to better align with outcomes.

Current Appointments & Affiliations

Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2019

Contact Information

Hanes House Room 154, Box 102359, Durham, NC 27710
sonali.advani@duke.edu

Background
Education, Training, & Certifications
- Co-chief Fellow, Infectious Diseases, University of Alabama Birmingham 2016 - 2017
- Infectious Diseases Fellowship, University of Alabama Birmingham 2015 - 2017
- Internal Medicine Residency, University of Alabama Birmingham 2012 - 2015
- Research Fellow, Infectious Diseases & Hospital Epidemiology, Johns Hopkins University School of Medicine 2010 - 2012
- M.P.H., Johns Hopkins Unversity, Bloomberg School of Public Health 2010
- M.B.B.S., Padmashree Dr. D. Y. Patil Medical College (India) 2008
Medical Licensure
- 2019-00743. North Carolina. 2019
Academic Positions Outside Duke
- Associate Medical Director of Infection Prevention, Yale New Haven Hospital. 2017 - 2019
- Assistant Professor of Medicine, Yale School of Medicine, New Haven, CT. 2017 - 2019
Recognition
In the News
- JUL 27, 2019 Infectious Disease News
  
  Inappropriate urine culture practices contribute to overdiagnosis of CAUTIs
- APR 14, 2019 Infectious Disease News
  
  Q&A: The evolution of CAUTI and need for better metrics
- FEB 19, 2019 IDSA Foundation
  
  ID WOMEN OF THE FUTURE
- FEB 6, 2019 Medscape and SHEA Editorial Collaboration
  
  Pre-op Urine Screening: Changing Our Culture
- JAN 15, 2019 Medscape and SHEA Editorial Collaboration
  
  The Latest Dirt on Hospital Cleanliness
- JAN 1, 2019 Infectious Disease News
  
  #BeASteward: IDSA develops antimicrobial stewardship curriculum for ID fellows
- NOV 28, 2018 New York Times
  
  A Rash on Her Palms and the Bottoms of Her Feet Was the Clue That Turned the Case
- OCT 18, 2018 Infectious Disease News
  
  Algorithm reduces urine culture orders and CAUTIs
- JUL 12, 2018 Medscape and SHEA Editorial Collaboration
  
  What's the Verdict for UTIs in Women and Children?
- MAR 22, 2018 Medscape and SHEA Editorial Collaboration
  
  Survival of the Slimiest: The Persistent Nature of Biofilms
- NOV 11, 2013 Infectious Disease News
  
  CLABSI risk increased by central catheter dwell time
- AUG 1, 2012
  
  Nucleic acid tests helpful in identifying respiratory viruses, but caution urged
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Development of validated diagnostic stewardship strategy to improve reflex urine culture utilization and diagnosis of urinary tract infections awarded by The Society for Healthcare Epidemiology of America 2021
Fellowships, Supported Research, & Other Grants
- Multidisciplinary K12 Urologic Research Career Development Program awarded by Duke University/NIH 2020 - 2021
- The Duke-UNC Prevention Epicenters Program awarded by Centers for Disease Control and Prevention 2020 - 2021
- SHEPheRD awarded by Centers for Disease Control and Prevention 2018 - 2020
- The Duke-UNC Prevention Epicenters Program awarded by Centers for Disease Control and Prevention 2016 - 2021
External Relationships
- IPEC experts, LLC
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Advani SD, Anderson DJ. Chlorhexidine for skin antisepsis: making the case to keep peripheral venous catheters CLEAN. Lancet Infect Dis. 2021 Feb 1;
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  - Nguyen KA, Le DQ, Bui YT, Advani SD, Renzulli J, Kenney PA, et al. Incidence, risk factors, and outcome of Clostridioides difficile infection following urological surgeries. World Journal of Urology. 2021 Jan 1;
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  - Ling D, Seidelman J, Dodds-Ashley E, Lewis S, Moehring RW, Anderson DJ, et al. Navigating reflex urine culture practices in community hospitals: Need for a validated approach. Am J Infect Control. 2020 Dec;48(12):1549–51.
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  - Seidelman JL, Lewis SS, Advani SD, Akinboyo IC, Epling C, Case M, et al. Universal masking is an effective strategy to flatten the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) healthcare worker epidemiologic curve. Infect Control Hosp Epidemiol. 2020 Dec;41(12):1466–7.
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  - Murthy AR, Hanrahan JA, Advani SD, Ashraf MS, Mills JP, Mody L, et al. State of the Pandemic Commentary: Preparing Nursing Homes for a Second Wave of COVID-19. Infect Control Hosp Epidemiol. 2020 Oct 20;1–9.
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  - Advani SD, Baker E, Cromer A, Wood B, Crawford KL, Crane L, et al. Assessing severe acute respiratory coronavirus virus 2 (SARS-CoV-2) preparedness in US community hospitals: A forgotten entity. Infect Control Hosp Epidemiol. 2020 Oct 7;1–4.
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  - Advani SD, Smith BA, Lewis SS, Anderson DJ, Sexton DJ. Universal masking in hospitals in the COVID-19 era: Is it time to consider shielding? Infect Control Hosp Epidemiol. 2020 Sep;41(9):1066–7.
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  - Fakih MG, Advani SD. Striving to Reach the Optimal Measure for Catheter-Associated Urinary Tract Infection (CAUTI): Moving to Catheter Harm. Clin Infect Dis. 2020 Jul 17;
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  - Advani SD, Yarrington ME, Smith BA, Anderson DJ, Sexton DJ. Are we forgetting the "universal" in universal masking? Current challenges and future solutions. Infect Control Hosp Epidemiol. 2020 Jul 16;1–2.
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  - Advani SD, Schwartz IS, Spivak ES, Sutton JD. Re: 'Antibiotic treatment for 6 days versus 12 days in patients with severe cellulitis' by Cranendonk et al. Clin Microbiol Infect. 2020 May;26(5):654–5.
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  - Pepe DE, Maloney M, Leung V, Harizaj A, Banach DB, Dembry L-M, et al. An evaluation of metrics for assessing catheter-associated urinary tract infections (CAUTIs): A statewide comparison. Infect Control Hosp Epidemiol. 2020 Apr;41(4):481–3.
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  - Advani SD, Murray TS, Murdzek CM, Aniskiewicz MJ, Bizzarro MJ. Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit-specific NHSN definitions. Infect Control Hosp Epidemiol. 2020 Feb;41(2):181–6.
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  - Advani SD, Gao CA, Datta R, Sann L, Smith C, Leapman MS, et al. Knowledge and Practices of Physicians and Nurses Related to Urine Cultures in Catheterized Patients: An Assessment of Adherence to IDSA Guidelines. Open Forum Infect Dis. 2019 Aug 1;6(8).
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  - Fakih MG, Advani SD, Vaughn VM. Diagnosis of urinary tract infections: need for a reflective rather than reflexive approach. Infect Control Hosp Epidemiol. 2019 Jul;40(7):834–5.
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  - Advani SD, Fakih MG. The evolution of catheter-associated urinary tract infection (CAUTI): Is it time for more inclusive metrics? Infect Control Hosp Epidemiol. 2019 Jun;40(6):681–5.
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  - Gaston DC, Peaper DR, Advani SD. Fever, Rash, and Migratory Polyarthralgias. Jama. 2019 May 21;321(19):1930–1.
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  - Luther VP, Shnekendorf R, Abbo LM, Advani S, Armstrong WS, Barsoumian AE, et al. Antimicrobial Stewardship Training for Infectious Diseases Fellows: Program Directors Identify a Curriculum Need. Clin Infect Dis. 2018 Sep 28;67(8):1285–7.
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  - Advani SD, Nellore A, Hadjivassiliou G, Eckhoff DE, Salzman D, Lavie D, et al. Two Cases and a Review of Graft-Versus-Host Disease and the Role of Hepatitis C Treatment in Liver Transplant Patients. Prog Transplant. 2018 Sep;28(3):267–70.
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  - Advani SD, Lee RA, Long M, Schmitz M, Camins BC. The Impact of 2015 NHSN Catheter-associated Urinary Tract Infection (CAUTI) Definition Change on Central Line-associated Bloodstream Infection (CLABSI) Rates and CLABSI Prevention Efforts at an Academic Medical Center. Infect Control Hosp Epidemiol. 2018 Jul;39(7):878–80.
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  - Javier-DesLoges JF, Ghabili Amirkhiz K, Su JJ, Kenney PA, Advani S, Hittelman AB, et al. MP80-02 LEVERAGING STRUCTURED DATA IN AN ENTERPRISE-WIDE ELECTRONIC HEALTH RECORD TO IDENTIFY RISK FACTORS FOR POSTOPERATIVE URINARY RETENTION. Journal of Urology. 2018 Apr;199(4S).
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  - Datta R, Advani S, Rink A, Bianco L, Van Ness PH, Quagliarello V, et al. Frequency of Infection during Fever Episodes among Long-Term Care Residents. J Gerontol Geriatr Res. 2018;7(2).
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  - Advani SD, Lee RA, Schmitz M, Camins BC. Impact of Changes to the National Healthcare Safety Network (NHSN) Definition on Catheter-Associated Urinary Tract Infection (CAUTI) Rates in Intensive Care Units at an Academic Medical Center. Infect Control Hosp Epidemiol. 2017 May;38(5):621–3.
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  - Advani S, Lee R, Schmitz M, Long M, Camins B. 2015 NHSN CAUTI Definition Change and Its Impact on CLABSI Rates at an Academic Medical Center. Open Forum Infectious Diseases. 2017 Jan;4(Suppl 1):S180–S180.
  - Advani S, Lee R, Schmitz M, Camins B. Impact of Change in the National Healthcare Safety Network (NHSN) Definition of Catheter-Associated Urinary Tract Infections (CAUTIs) on the CAUTI Rates in Intensive Care Units at an Academic Medical Center. Open Forum Infectious Diseases. 2016 Dec 1;3(suppl_1).
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  - Kovacich A, Tamma PD, Advani S, Popoola VO, Colantuoni E, Gosey L, et al. Peripherally Inserted Central Venous Catheter Complications in Children Receiving Outpatient Parenteral Antibiotic Therapy (OPAT). Infect Control Hosp Epidemiol. 2016 Apr;37(4):420–4.
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  - Morden A, Advani S, Gosey L, Popoola V, Milstone AM. 981Catheter Complications in Children Discharged with Peripherally Inserted Central Catheters (PICCs). Open Forum Infectious Diseases. 2014 Dec;1(Suppl 1):S285–S285.
  - Milstone AM, Reich NG, Advani S, Yuan G, Bryant K, Coffin SE, et al. Catheter dwell time and CLABSIs in neonates with PICCs: a multicenter cohort study. Pediatrics. 2013 Dec;132(6):e1609–15.
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  - Advani S, Sengupta A, Milstone AM. Postdischarge surveillance to identify subsequent methicillin-resistant Staphylococcus aureus infections in colonized children. Am J Infect Control. 2013 Oct;41(10):939–41.
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  - Chapman AK, Aucott SW, Gilmore MM, Advani S, Clarke W, Milstone AM. Absorption and tolerability of aqueous chlorhexidine gluconate used for skin antisepsis prior to catheter insertion in preterm neonates. J Perinatol. 2013 Oct;33(10):768–71.
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  - Jumani K, Advani S, Reich NG, Gosey L, Milstone AM. Risk factors for peripherally inserted central venous catheter complications in children. Jama Pediatr. 2013 May;167(5):429–35.
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  - Advani S, Sengupta A, Forman M, Valsamakis A, Milstone AM. Detecting respiratory viruses in asymptomatic children. Pediatr Infect Dis J. 2012 Dec;31(12):1221–6.
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  - Forman MS, Advani S, Newman C, Gaydos CA, Milstone AM, Valsamakis A. Diagnostic performance of two highly multiplexed respiratory virus assays in a pediatric cohort. J Clin Virol. 2012 Oct;55(2):168–72.
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  - Advani S, Reich NG, Sengupta A, Gosey L, Milstone AM. Central line-associated bloodstream infection in hospitalized children with peripherally inserted central venous catheters: extending risk analyses outside the intensive care unit. Clin Infect Dis. 2011 May;52(9):1108–15.
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Teaching & Mentoring
Teaching Activities
- Healthcare epidemiology at Yale School of Public Health YSPH EMD530 (Healthcare Epidemiology Course)
  
  Infectious Diseases Society of America Antibiotic Stewardship curriculum Workgroup member Basic Antibiotic Stewardship Curriculum and Advanced Stewardship Curriculum which is under development
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
Service to the Profession
Academic & Administrative Activities
- University Committees
  2015-2016 House Staff Council, University of Alabama at Birmingham, Birmingham, AL
  2012-2013 House Staff Council, University of Alabama at Birmingham, Montgomery, AL
  2009-2010 Events coordinator, J.B. Grant International Health Society, Johns Hopkins Bloomberg School of Public Health, Baltimore MD
  
  Medical School Committees
  2018-2019 Intern Selection Committee, Yale School of Medicine, New Haven, CT
  2018-2019 Diversity Committee, Yale School of Medicine, New Haven, CT
  2018-2019 DOM Committee, Yale School of Medicine, New Haven, CT
  
  Hospital Boards & Committees
  2019-2019 Member, Sepsis Inpatient Clinical Redesign, Yale New Haven Health System
  2018-2019 Physician Lead, System CAUTI Committee, Yale New Haven Health System
  2017-2019 Alternate Chair, Infection Control Committee, Yale New Haven Hospital
  2017-2019 Co-chair, CAUTI Performance Improvement Team, Yale New Haven Hospital
  2017-2019 Co-chair, CLABSI Performance Improvement Team, Yale New Haven Hospital
  2017-2019 Member, C. difficile Performance Improvement Team, Yale New Haven Hospital
  2017-2019 Member, System CLABSI Committee, Yale New Haven Health System
  2015-2017 Member, Infection Control Committee, University of Alabama at Birmingham Hospital, AL
  2013-2015 Member, Infection Control Committee, Baptist South Medical Center, Montgomery, AL
  
  Regional, State and National Committees
  2017-2019 Member, Connecticut Department of Health (DPH) Reportable Diseases Committee
  2017-2019 Member, Connecticut DPH Healthcare Associated Infections Advisory Committee
  2017-2019 Member, Connecticut DPH Multi-Disciplinary AR/AMS Advisory Group

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Education, Training, & Certifications

Medical Licensure

Academic Positions Outside Duke

In the News

Awards & Honors

Subject Headings

Selected Grants

Fellowships, Supported Research, & Other Grants

External Relationships

Selected Publications

Academic Articles

Teaching Activities

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession

Academic & Administrative Activities