Stephanie Ann Eucker | Scholars@Duke

Stephanie Ann Eucker
Assistant Professor of Emergency Medicine

Current Research Interests

I am interested in the development of multimodal and non-pharmacologic pain management strategies in the Emergency Department with the goal of improving patient-oriented outcomes after acute pain presentations and preventing progression to persistent pain and disability.

Current Appointments & Affiliations

Assistant Professor of Emergency Medicine, Emergency Medicine, Clinical Science Departments 2021

Contact Information

2301 Erwin Road, DUMC 3096, Durham, NC 27710
2301 Erwin Road, DUMC 3096, Durham, NC 27710
stephanie.eucker@duke.edu (919) 681-0196

Background
Education, Training, & Certifications
- Resident, Emergency Medicine, University of Virginia 2010 - 2013
- MD./PhD., University of Pennsylvania, School of Medicine 2010
Previous Appointments & Affiliations
- Assistant Professor of Surgery, Emergency Medicine, Clinical Science Departments 2013 - 2020
Expertise
Subject Headings
- Pain Management
- Pain--Treatment
Research
Selected Grants
- Mid-Atlantic praGmatic NETwork for Inclusive Clinical trials in emergency care (MAGNETIC) awarded by National Institutes of Health 2023 - 2028
- Duke Pain Early-phase Research Clinical Center (PERC) awarded by National Institutes of Health 2019 - 2024
- Emergency Department Acupuncture for Musculoskeletal Pain Management awarded by Substance Abuse and Mental Health Services Administration 2020 - 2023
- Pilot Study of Multimodal Cognitive Behavioral Therapy-Informed Physical Therapy in the Management of Neck and Back Pain in the Emergency Department (Multi-ED) awarded by Emergency Medicine Foundation 2022 - 2023
- PReventing Emerging infections through Vaccine EffectiveNess Testing II - COVID (Project PREVENT II) awarded by University of California - Los Angeles 2022 - 2023
- PROmotion of COVid-19 VA(X)ccination in the Emergency Department - PROCOVAXED awarded by University of California - San Francisco 2021 - 2023
- Implementation of Interprofessional Emergency Department-Initiated Medication Treatment for Opioid Use Disorder (Inter-EM) awarded by Physician Assistant Foundation 2022
- Clinical Trials Network: New England Node: CTN0099 ED-INNOVATION supplement awarded by Yale University 2020 - 2021
- Clinical Trials Network: New England Node: CTN0099 ED-INNOVATION supplement awarded by McLean Hospital 2020
- EQUIPPED (Enhancing Quality of Provider Prescribing for Older Adults in the Emergency Department) awarded by Emory University 2016 - 2019
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Gentsch, Alexzandra T., Jonathan Butler, Kelli O’Laughlin, Stephanie A. Eucker, AnnaMarie Chang, Herbie Duber, Rachel E. Geyer, et al. “Perspectives of COVID-19 vaccine-hesitant emergency department patients to inform messaging platforms to promote vaccine uptake.” Acad Emerg Med 30, no. 1 (January 2023): 32–39. https://doi.org/10.1111/acem.14620.
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  - Eucker, Stephanie A., Oliver Glass, Catherine A. Staton, Mitchell R. Knisely, Amy O’Regan, Christi De Larco, Michelle Mill, et al. “Acupuncture for acute musculoskeletal pain management in the emergency department and continuity clinic: a protocol for an adaptive pragmatic randomised controlled trial.” Bmj Open 12, no. 9 (September 23, 2022): e061661. https://doi.org/10.1136/bmjopen-2022-061661.
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  - Baumann, Brigitte M., Robert M. Rodriguez, Amy M. DeLaroche, David Rayburn, Stephanie A. Eucker, Nicole L. Nadeau, Lisa A. Drago, et al. “Factors Associated With Parental Acceptance of COVID-19 Vaccination: A Multicenter Pediatric Emergency Department Cross-Sectional Analysis.” Ann Emerg Med 80, no. 2 (August 2022): 130–42. https://doi.org/10.1016/j.annemergmed.2022.01.040.
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  - Eucker, Stephanie A., Mitchell R. Knisely, and Corey Simon. “Nonopioid Treatments for Chronic Pain-Integrating Multimodal Biopsychosocial Approaches to Pain Management.” Jama Netw Open 5, no. 6 (June 1, 2022): e2216482. https://doi.org/10.1001/jamanetworkopen.2022.16482.
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  - Rodriguez, Robert M., Kelli O’Laughlin, Stephanie A. Eucker, Anna Marie Chang, Kristin L. Rising, Graham Nichol, Alena Pauley, et al. “PROmotion of COvid-19 VA(X)ccination in the Emergency Department-PROCOVAXED: study protocol for a cluster randomized controlled trial.” Trials 23, no. 1 (April 21, 2022): 332. https://doi.org/10.1186/s13063-022-06285-x.
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  - Eswaran, Vidya, Anna Marie Chang, R Gentry Wilkerson, Kelli N. O’Laughlin, Brian Chinnock, Stephanie A. Eucker, Brigitte M. Baumann, et al. “Facemasks: Perceptions and use in an ED population during COVID-19.” Plos One 17, no. 4 (2022): e0266148. https://doi.org/10.1371/journal.pone.0266148.
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  - Eucker, Stephanie A., Shawna Foley, Sarah Peskoe, Alexander Gordee, Thomas Risoli, Frances Morales, and Steven Z. George. “Willingness to use nonpharmacologic treatments for musculoskeletal pain in the emergency department: a cross-sectional study.” Pain Rep 7, no. 5 (2022): e1027. https://doi.org/10.1097/PR9.0000000000001027.
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  - Flynn, Spencer B., Alexander Gordee, Maragatha Kuchibhatla, Steven Z. George, and Stephanie A. Eucker. “Moving toward patient-centered care in the emergency department: Patient-reported expectations, definitions of success, and importance of improvement in pain-related outcomes.” Acad Emerg Med 28, no. 11 (November 2021): 1286–98. https://doi.org/10.1111/acem.14328.
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  - Vaughan, Camille P., Ula Hwang, Ann E. Vandenberg, Traci Leong, Daniel Wu, Melissa B. Stevens, Carolyn Clevenger, et al. “Early prescribing outcomes after exporting the EQUIPPED medication safety improvement programme.” Bmj Open Qual 10, no. 4 (November 2021). https://doi.org/10.1136/bmjoq-2021-001369.
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  - Rodriguez, Robert M., Jesus R. Torres, Anna Marie Chang, Adrianne N. Haggins, Stephanie A. Eucker, Kelli N. O’Laughlin, Erik Anderson, et al. “The Rapid Evaluation of COVID-19 Vaccination in Emergency Departments for Underserved Patients Study.” Ann Emerg Med 78, no. 4 (October 2021): 502–10. https://doi.org/10.1016/j.annemergmed.2021.05.026.
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  - Limkakeng, Alexander T., Pratik Manandhar, Alaatin Erkanli, Stephanie A. Eucker, Adam Root, and Deepak Voora. “United States Emergency Department Use of Medications with Pharmacogenetic Recommendations.” West J Emerg Med 22, no. 6 (September 23, 2021): 1347–54. https://doi.org/10.5811/westjem.2021.5.51248.
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  - Eucker, Stephanie A., Pratik Manandhar, Kami Arulraja, Deepti Agnihotri, Charles V. Pollack, and Caroline Freiermuth. “Higher daily pain severity after emergency department visits is associated with lower return-to-work rates.” Am J Emerg Med 45 (July 2021): 48–53. https://doi.org/10.1016/j.ajem.2021.02.040.
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  - Funke, Mary, Marcus C. Kaplan, Holly Glover, Nicole Schramm-Sapyta, Andrew Muzyk, Jennifer Mando-Vandrick, Alexander Gordee, Maragatha Kuchibhatla, Emily Sterrett, and Stephanie A. Eucker. “Increasing Naloxone Prescribing in the Emergency Department Through Education and Electronic Medical Record Work-Aids.” Jt Comm J Qual Patient Saf 47, no. 6 (June 2021): 364–75. https://doi.org/10.1016/j.jcjq.2021.03.002.
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  - Vandenberg, Ann E., Michelle Kegler, S Nicole Hastings, Ula Hwang, Daniel Wu, Melissa B. Stevens, Carolyn Clevenger, et al. “Sequential implementation of the EQUIPPED geriatric medication safety program as a learning health system.” Int J Qual Health Care 32, no. 7 (September 23, 2020): 470–76. https://doi.org/10.1093/intqhc/mzaa077.
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  - Ring, Joshua, Sarah Peskoe, Congwen Zhao, Benjamin W. Friedman, Steven Z. George, and Stephanie A. Eucker. “Depression and Functional Outcomes in Patients Presenting to the Emergency Department With Low Back Pain.” Acad Emerg Med 27, no. 8 (August 2020): 725–33. https://doi.org/10.1111/acem.13957.
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  - Hughes, Jaime M., Caroline E. Freiermuth, Megan Shepherd-Banigan, Luna Ragsdale, Stephanie A. Eucker, Karen Goldstein, S Nicole Hastings, et al. “Emergency Department Interventions for Older Adults: A Systematic Review.” J Am Geriatr Soc 67, no. 7 (July 2019): 1516–25. https://doi.org/10.1111/jgs.15854.
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  - Sakamoto, Jeffrey T., Heather Burrell Ward, Joao Ricardo Nickenig Vissoci, and Stephanie A. Eucker. “Are Nonpharmacologic Pain Interventions Effective at Reducing Pain in Adult Patients Visiting the Emergency Department? A Systematic Review and Meta-analysis.” Acad Emerg Med 25, no. 8 (August 2018): 940–57. https://doi.org/10.1111/acem.13411.
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  - Good, Miranda E., Stephanie A. Eucker, Jun Li, Hannah M. Bacon, Susan M. Lang, Joshua T. Butcher, Tyler J. Johnson, et al. “Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone.” Jci Insight 3, no. 6 (March 22, 2018). https://doi.org/10.1172/jci.insight.96272.
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  - Patel, Anjni, Mateus Mazorra Coelho Vieira, John Abraham, Nick Reid, Tu Tran, Kevin Tomecsek, João Ricardo N. Vissoci, Stephanie Eucker, Charles J. Gerardo, and Catherine A. Staton. “Quality of the Development of Traumatic Brain Injury Clinical Practice Guidelines: A Systematic Review.” Plos One 11, no. 9 (2016): e0161554. https://doi.org/10.1371/journal.pone.0161554.
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  - Sullivan, Sarah, Stephanie A. Eucker, David Gabrieli, Connor Bradfield, Brittany Coats, Matthew R. Maltese, Jongho Lee, Colin Smith, and Susan S. Margulies. “White matter tract-oriented deformation predicts traumatic axonal brain injury and reveals rotational direction-specific vulnerabilities.” Biomech Model Mechanobiol 14, no. 4 (August 2015): 877–96. https://doi.org/10.1007/s10237-014-0643-z.
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  - Eucker, Stephanie A., Tyler W. Barrett, and David L. Schriger. “Annals of Emergency Medicine Journal Club. Are 2 drugs better than 1 for acute agitation? A discussion on black box warnings, waiver of informed consent, and the ethics of enrolling impaired subjects in clinical trials: Answers to the January 2013 Journal Club questions.” Ann Emerg Med 61, no. 6 (June 2013): 708–16. https://doi.org/10.1016/j.annemergmed.2013.03.020.
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  - Eucker, Stephanie A., Tyler W. Barrett, and David L. Schriger. “Are two drugs better than one for acute agitation? A discussion on black box warnings, waiver of informed consent, and the ethics of enrolling impaired subjects in clinical trials.” Ann Emerg Med 61, no. 1 (January 2013): 82–83. https://doi.org/10.1016/j.annemergmed.2012.10.040.
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  - Hashmi, S. K., S. Sullivan, S. A. Eucker, B. Coats, J. Lee, and S. S. Margulies. “FEM-predicted regional tissue strains aligned with the white matter tracts predict axonal injury.” 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012, June 29, 2012, 151–52. https://doi.org/10.1109/NEBC.2012.6207008.
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  - Coats, Brittany, Stephanie A. Eucker, Sarah Sullivan, and Susan S. Margulies. “Finite element model predictions of intracranial hemorrhage from non-impact, rapid head rotations in the piglet.” Int J Dev Neurosci 30, no. 3 (May 2012): 191–200. https://doi.org/10.1016/j.ijdevneu.2011.12.009.
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  - Friess, Stuart H., Jill Ralston, Stephanie A. Eucker, Mark A. Helfaer, Colin Smith, and Susan S. Margulies. “Neurocritical care monitoring correlates with neuropathology in a swine model of pediatric traumatic brain injury.” Neurosurgery 69, no. 5 (November 2011): 1139–47. https://doi.org/10.1227/NEU.0b013e3182284aa1.
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  - Eucker, Stephanie A., Colin Smith, Jill Ralston, Stuart H. Friess, and Susan S. Margulies. “Physiological and histopathological responses following closed rotational head injury depend on direction of head motion.” Exp Neurol 227, no. 1 (January 2011): 79–88. https://doi.org/10.1016/j.expneurol.2010.09.015.
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  - Eucker, Stephanie A., Brenton D. Hoffman, Rahul Natesh, Jill Ralston, William M. Armstead, and Susan S. Margulies. “Development of a fluorescent microsphere technique for rapid histological determination of cerebral blood flow.” Brain Res 1326 (April 22, 2010): 128–34. https://doi.org/10.1016/j.brainres.2010.02.059.
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  - Ibrahim, Nicole G., Rahul Natesh, Spencer E. Szczesny, Karen Ryall, Stephanie A. Eucker, Brittany Coats, and Susan S. Margulies. “In situ deformations in the immature brain during rapid rotations.” J Biomech Eng 132, no. 4 (April 2010): 044501. https://doi.org/10.1115/1.4000956.
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  - Zhou, Chao, Stephanie A. Eucker, Turgut Durduran, Guoqiang Yu, Jill Ralston, Stuart H. Friess, Rebecca N. Ichord, Susan S. Margulies, and Arjun G. Yodh. “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury.” J Biomed Opt 14, no. 3 (2009): 034015. https://doi.org/10.1117/1.3146814.
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  - Zhou, C., T. Durduran, G. Yu, S. Eucker, S. Friess, R. Ichord, S. Margulies, and A. G. Yodh. “Real-time monitoring of hemodynamic changes in neonatal pig brain with head trauma injury.” Optics Infobase Conference Papers, January 1, 2006.
  - Eucker, Stephanie A., Jennifer Lisauskas, Michael R. Courtois, and Sándor J. Kovács. “Analysis of left ventricular hemodynamics in physiological hyperspace.” J Appl Physiol (1985) 92, no. 1 (January 2002): 323–30. https://doi.org/10.1152/japplphysiol.00560.2001.
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  - Eucker, S. A., J. B. Lisauskas, J. Singh, and S. J. Kovács. “Phase plane analysis of left ventricular hemodynamics.” J Appl Physiol (1985) 90, no. 6 (June 2001): 2238–44. https://doi.org/10.1152/jappl.2001.90.6.2238.
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  - Eucker, S., J. B. Lisauskas, J. Singh, and S. J. Kovacs. “Human cardiac physiology in the phase plane: The ejection fraction to limit cycle area relation.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 1 (December 1, 1999): 229.
- Conference Papers
  - Flynn, Spencer, Alexander Gordee, Maragatha Kuchibhatla, Steven George, and Stephanie Eucker. “Moving Towards Patient-Centered Care in the Emergency Department: Importance of Improvement in Pain-Related Outcomes.” In Journal of Pain, 22:593–593, 2021.
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  - Hunt, A., M. Kelly, G. Wilkerson, N. Anaya, J. Graterol, S. Eucker, E. Anderson, et al. “Facemasks: Perceptions and Use in an Emergency Department Population During COVID-19.” In Annals of Emergency Medicine, 78:S21–S21, 2021.
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  - Schlientz, D. M., L. Previll, S. Eucker, C. Vaughan, U. Hwang, and S. N. Hastings. “Potentially Inappropriate Medications Prescribed in the Emergency Department: EQUIPPED Project Baseline Data.” In Journal of the American Geriatrics Society, 67:S157–S157. WILEY, 2019.
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  - Eucker, S., S. Peskoe, S. Foley, and S. George. “(324) Characterizing Expectations for Functional Outcomes in Emergency Department Patients with Musculoskeletal Pain.” In The Journal of Pain, 20:S56–S56. Elsevier BV, 2019. https://doi.org/10.1016/j.jpain.2019.02.020.
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  - Simon, C., S. Eucker, H. Lee, and M. Horn. “(285) Opioid Prescription in the Emergency Department for Patients with Axial Pain: Comparisons by Age Group.” In The Journal of Pain, 20:S45–46. Elsevier BV, 2019. https://doi.org/10.1016/j.jpain.2019.01.207.
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  - Good, Miranda Elizabeth, Stephanie A. Eucker, Jun Li, Hannah M. Bacon, Susan M. Lang, Joshua T. Butcher, Tyler J. Johnson, Zhiyi Zuo, and Brant E. Isakson. “Endothelial Cell Pannexin1 Modulates Severity of Ischemic Stroke by Regulating Cerebral Inflammation and Myogenic Tone.” In Faseb Journal, Vol. 32, 2018.
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  - Good, Miranda Elizabeth, Hannah M. Bacon, Stephanie A. Eucker, Susan M. Lang, Joshua T. Butcher, Tyler J. Johnson, Jun Li, Zhiyi Zuo, and Brant E. Isakson. “Endothelial Pannexin1 can regulate cerebral myogenic tone development and severity of ischemic stroke.” In Faseb Journal, Vol. 31, 2017.
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  - Eucker, S., K. Mutter, D. Bose, E. Wu, and M. Sochor. “254 Role of Airbag Use on Head Injury Outcomes in Side versus Frontal Impact Car Crashes.” In Annals of Emergency Medicine, 60:S92–S92. Elsevier BV, 2012. https://doi.org/10.1016/j.annemergmed.2012.06.232.
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  - Zhou, C., S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh. “Diffuse optical monitoring of cerebral hemodynamics in piglet with traumatic brain injury.” In Journal of Cerebral Blood Flow and Metabolism, 29:S33–34. NATURE PUBLISHING GROUP, 2009.
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  - Coats, Brittany, Jeffrey Kras, Stephanie Eucker, and Susan S. Margulies. “SEVERITY OF EXTRA-AXIAL HEMORRHAGE FROM NON-IMPACT INERTIAL HEAD ROTATION IN THE IMMATURE PIG VARIES WITH DIRECTION.” In Journal of Neurotrauma, 26:A86–A86. MARY ANN LIEBERT INC, 2009.
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  - Eucker, Stephanie, Colin Smith, Jill Ralston, Stuart Friess, and Susan Margulies. “RAPID SAGITTAL ROTATIONS PRODUCE MORE SEVERE PHYSIOLOGICAL AND HISTOPATHOLOGICAL RESPONSES IN NEONATAL PIGLETS THAN CORONAL OR HORIZONTAL ROTATIONS.” In Journal of Neurotrauma, 26:A22–A22. MARY ANN LIEBERT INC, 2009.
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  - Ibrahim, Nicole, Stephanie Eucker, Jill Ralston, Colin Smith, and Susan Margulies. “DEFORMATION THRESHOLD FOR AXONAL INJURY IS LARGER IN TODDLER THAN INFANT PIGS.” In Journal of Neurotrauma, 26:A84–A84. MARY ANN LIEBERT INC, 2009.
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  - Eucker, Stephanie, Stuart Friess, Jill Ralston, and Susan Margulies. “Regional cerebral blood flow response following brain injury depends on direction of head motion.” In Journal of Neurotrauma, 25:923–923. MARY ANN LIEBERT INC, 2008.
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  - Friess, Stuart, Jill Ralston, Stephanie Eucker, Mark Helfaer, and Susan Margulies. “Temporal changes in brain tissue oxygen and metabolism following diffuse traumatic brain injury in piglets.” In Journal of Neurotrauma, 25:886–886. MARY ANN LIEBERT INC, 2008.
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  - Eucker, Stephanie, Colin Smith, Stuart Friess, Maryam Naim, Jill Ralston, and Susan Margulies. “Severity of damage following inertial brain injury depends on direction of head rotation.” In Journal of Neurotrauma, 24:1272–1272. MARY ANN LIEBERT INC, 2007.
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  - Eucker, Stephanie, Maryam Naim, Colin Smith, Stuart Friess, Jill Ralston, Chao Zhou, Turgut Durduran, Guoqiang Yu, Armn Yodh, and Susan Margulies. “Hypertonic saline increases cerebral blood flow after traumatic brain injury.” In Journal of Neurotrauma, 23:1024–1024. MARY ANN LIEBERT INC, 2006.
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  - Zhou, C., T. Durduran, G. Yu, S. Eucker, S. Friess, R. Ichord, S. Margulies, and A. G. Yodh. “Real-time monitoring of hemodynamic changes in neonatal pig brain with head trauma injury.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/bio.2006.mc5.
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  - Eucker, S., R. Ichord, S. Friess, C. Zhou, T. Durduran, G. Yu, A. Yodh, and S. Margulies. “Direction dependence of rotational accelerational injury on cerebrovascular hemodynamics response depends on direction of angular acceleration.” In Journal of Neurotrauma, 22:1254–1254. MARY ANN LIEBERT INC, 2005.
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Education, Training, & Certifications

Previous Appointments & Affiliations

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Conference Papers