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Stephanie Ann Eucker

Assistant Professor of Emergency Medicine
Emergency Medicine
2301 Erwin Road, DUMC 3096, Durham, NC 27710
2301 Erwin Road, DUMC 3096, Durham, NC 27710


Stephanie Eucker, MD, PhD, FACEP is an Assistant Professor and Assistant Director of Acute Care Research in the Duke University Department of Emergency Medicine. Her primary research interest is in preventing and treating chronic pain, disability, and opioid use disorder (OUD) by incorporating innovative multimodal and nonpharmacologic pain management strategies in the Emergency Department (ED). Her broad clinical and research training includes Emergency Medicine, Bioengineering, Clinical and Translational research. Her research comprises three main synergistic areas of focus: (1) innovative nonpharmacologic ED pain care models, (2) patient-centered, personalized medicine approaches to pain care selection, and (3) transforming ED care best practices. 

In the nonpharmacologic realm, Dr. Eucker is PI of a SAMHSA-funded pragmatic randomized clinical trial of acupuncture to treat acute musculoskeletal pain in the ED, to which her team has successfully recruited 599 patients with >50% identifying as African-American and/or Latinx. Her team successfully developed an approach to acupuncture that is feasible for the fast-paced ED setting, produces significantly greater pain reductions than usual care alone, and is used and rated highly acceptable by diverse ED patients with acute musculoskeletal pain.

In the patient-centered focus, she leads several ongoing studies investigating the relationship between biopsychosocial factors and pain-related outcomes in ED patients, patient expectations for ED pain management, and the relationship between post-ED care pathways and downstream opioid use.

Regarding research on improving and implementing ED best practices, Dr. Eucker is site-PI for the multi-site PROCOVAXED study aiming to improve COVID-19 vaccination rates among ED patients through multi-media informational platforms. She has been a co-investigator in a multi-center AHRQ implementation study to improve safe ED prescribing for older adults. She also leads a multi-professional quality improvement and research effort to improve naloxone and buprenorphine prescribing for ED patients with opioid overdose and OUD. She has also partnered with Durham County and other community partners to improve linkages to care through peer support specialists in the ED.

Regarding training, Dr. Eucker has mentored numerous trainees in research, including undergraduates, graduate students, medical student, resident physicians, physician assistants and junior faculty over the past several years.  She is highly experienced at engaging learners at their level of understanding and interest in the research process, from novice researchers to those with extensive experience.  Her mentees have coauthored numerous publications and progressed to leading projects under her mentorship.

Current Appointments & Affiliations

Assistant Professor of Emergency Medicine · 2021 - Present Emergency Medicine, Clinical Science Departments

Education, Training & Certifications

University of Pennsylvania, School of Medicine · 2010 MD./PhD.