Current Appointments & Affiliations
Associate Professor in Surgery
·
2021 - Present
Surgery, Surgical Sciences,
Surgery
Associate Professor of Pathology
·
2022 - Present
Pathology,
Clinical Science Departments
Recent Publications
Knockdowns of CD3zeta Chain in Primary NK Cells Illustrate Modulation of Antibody-Dependent Cellular Cytotoxicity Against Human Immunodeficiency Virus-1.
Journal Article AIDS Res Hum Retroviruses · November 2024 Multifaceted natural killer (NK) cell activities are indispensable for controlling human immunodeficiency virus (HIV)-1 transmission and pathogenesis. Among the diverse functions of NK cells, antibody-dependent cellular cytotoxicity (ADCC) has been shown t ... Full text Link to item CiteNK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage.
Journal Article PLoS Pathog · August 2024 Natural killer (NK) cells play a critical role in virus control. However, it has remained largely unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic. To address this deficit, we employed a validated experimental NK ce ... Full text Link to item CiteUpregulation of the NKG2D Ligand ULBP2 by JC Polyomavirus Infection Promotes Immune Recognition by Natural Killer Cells.
Journal Article J Infect Dis · June 14, 2024 BACKGROUND: JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a potentially fatal complication of severe immune suppression with no effective treatment. Natural killer (NK) cells play critical roles in defense against viral i ... Full text Link to item CiteRecent Grants
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029Heterosubtypic immunity to influenza virus mediated by MHC-E-restricted memory NK cells
ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2021 - 2026Fine Mechanisms of Adaptive NK Cell Formation Against HIV and SIV
ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2021 - 2026View All Grants
Education, Training & Certifications
Swiss Federal Institute of Technology-EPFL Lausanne (Switzerland) ·
2007
Ph.D.
University of Geneva (Switzerland) ·
2002
M.S.
University of Geneva (Switzerland) ·
2000
B.S.