Scholars@Duke

• Research
• 

  Selected Grants

  • Comparison of Dyspnea Measurement Instruments in Acute Heart Failure awarded by Heart Failure Society of America 2017 - 2019
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Greene, Stephen J., Adam D. DeVore, Shubin Sheng, Gregg C. Fonarow, Javed Butler, Robert M. Califf, Adrian F. Hernandez, et al. “Representativeness of a Heart Failure Trial by Race and Sex: Results From ASCEND-HF and GWTG-HF.” Jacc Heart Fail 7, no. 11 (November 2019): 980–92. https://doi.org/10.1016/j.jchf.2019.07.011.
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    • Greene, Stephen J., G Michael Felker, Anna Giczewska, Andreas P. Kalogeropoulos, Andrew P. Ambrosy, Hrishikesh Chakraborty, Adam D. DeVore, et al. “Spironolactone in Acute Heart Failure Patients With Renal Dysfunction and Risk Factors for Diuretic Resistance: From the ATHENA-HF Trial.” Can J Cardiol 35, no. 9 (September 2019): 1097–1105. https://doi.org/10.1016/j.cjca.2019.01.022.
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    • Greene, Stephen J., and Robert M. Califf. “Reframing Global Variation in Heart Failure Trials: Thinking Beyond Location on the Map.” Jacc. Heart Failure 7, no. 4 (April 2019): 347–49. https://doi.org/10.1016/j.jchf.2018.12.012.
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    • Greene, Stephen J., and G Michael Felker. “The Urgency of Doing: Addressing Gaps in Use of Evidence-Based Medical Therapy for Heart Failure.” Jacc. Heart Failure 7, no. 1 (January 2019): 22–24. https://doi.org/10.1016/j.jchf.2018.11.006.
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    • Gori, Mauro, Paolo Canova, Alice Calabrese, Giovanni Cioffi, Roberto Trevisan, Renata De Maria, Aurelia Grosu, et al. “Strategy to identify subjects with diabetes mellitus more suitable for selective echocardiographic screening: The DAVID-Berg study.” International Journal of Cardiology 248 (December 2017): 414–20. https://doi.org/10.1016/j.ijcard.2017.06.101.
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    • Khan, Muhammad Shahzeb, Gregg C. Fonarow, Ali Ahmed, Stephen J. Greene, Muthiah Vaduganathan, Hassan Khan, Catherine Marti, Mihai Gheorghiade, and Javed Butler. “Dose of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Outcomes in Heart Failure: A Meta-Analysis.” Circulation. Heart Failure 10, no. 8 (August 2017). https://doi.org/10.1161/circheartfailure.117.003956.
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    • Ambrosy, Andrew P., Ankeet S. Bhatt, Dianne Gallup, Kevin J. Anstrom, Javed Butler, Adam D. DeVore, G Michael Felker, et al. “Trajectory of Congestion Metrics by Ejection Fraction in Patients With Acute Heart Failure (from the Heart Failure Network).” The American Journal of Cardiology 120, no. 1 (July 2017): 98–105. https://doi.org/10.1016/j.amjcard.2017.03.249.
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    • Greene, Stephen J., Muthiah Vaduganathan, and Mihai Gheorghiade. “Finding the road to recovery: therapeutic and clinical trial implications of dysfunctional viable myocardium in heart failure with reduced ejection fraction.” European Journal of Heart Failure 19, no. 7 (July 2017): 870–72. https://doi.org/10.1002/ejhf.842.
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    • Greene, Stephen J., Adrian F. Hernandez, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Javed Butler, Lukasz P. Cerbin, et al. “Hospitalization for Recently Diagnosed Versus Worsening Chronic Heart Failure: From the ASCEND-HF Trial.” J Am Coll Cardiol 69, no. 25 (June 27, 2017): 3029–39. https://doi.org/10.1016/j.jacc.2017.04.043.
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    • Senni, Michele, Stephen J. Greene, Javed Butler, Gregg C. Fonarow, and Mihai Gheorghiade. “Drug Development for Heart Failure With Preserved Ejection Fraction: What Pieces Are Missing From the Puzzle?” The Canadian Journal of Cardiology 33, no. 6 (June 2017): 768–76. https://doi.org/10.1016/j.cjca.2017.03.013.
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    • Ambrosy, Andrew P., Lukasz P. Cerbin, Adam D. DeVore, Stephen J. Greene, William E. Kraus, Christopher M. O’Connor, Ileana L. Piña, et al. “Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial.” Am Heart J 186 (April 2017): 130–38. https://doi.org/10.1016/j.ahj.2016.12.017.
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    • Brown, David A., Justin B. Perry, Mitchell E. Allen, Hani N. Sabbah, Brian L. Stauffer, Saame Raza Shaikh, John G. F. Cleland, et al. “Expert consensus document: Mitochondrial function as a therapeutic target in heart failure.” Nature Reviews. Cardiology 14, no. 4 (April 2017): 238–50. https://doi.org/10.1038/nrcardio.2016.203.
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    • Greene, Stephen J., Gregg C. Fonarow, Scott D. Solomon, Haris P. Subacius, Andrew P. Ambrosy, Muthiah Vaduganathan, Aldo P. Maggioni, et al. “Influence of atrial fibrillation on post-discharge natriuretic peptide trajectory and clinical outcomes among patients hospitalized for heart failure: insights from the ASTRONAUT trial.” European Journal of Heart Failure 19, no. 4 (April 2017): 552–62. https://doi.org/10.1002/ejhf.674.
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    • Greene, Stephen J., Stephen E. Epstein, Raymond J. Kim, Arshed A. Quyyumi, Robert T. Cole, Allen S. Anderson, Jane E. Wilcox, et al. “Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy.” J Cardiovasc Med (Hagerstown) 18, no. 4 (April 2017): 283–90. https://doi.org/10.2459/JCM.0000000000000303.
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    • Vaduganathan, Muthiah, Ayman Samman-Tahhan, Ravi B. Patel, Anita Kelkar, Lampros Papadimitriou, Vasiliki V. Georgiopoulou, Stephen J. Greene, et al. “Association between funding sources and the scope and outcomes of cardiovascular clinical trials: A systematic review.” Int J Cardiol 230 (March 1, 2017): 301–3. https://doi.org/10.1016/j.ijcard.2016.12.119.
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    • Butler, Javed, Stephen E. Epstein, Stephen J. Greene, Arshed A. Quyyumi, Sergey Sikora, Raymond J. Kim, Allen S. Anderson, et al. “Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.” Circ Res 120, no. 2 (January 20, 2017): 332–40. https://doi.org/10.1161/CIRCRESAHA.116.309717.
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    • Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial.” Jacc Heart Fail 5, no. 1 (January 2017): 1–13. https://doi.org/10.1016/j.jchf.2016.09.012.
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    • Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Laved Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes Findings From the ASCEND-HF Trial.” Jacc Heart Failure 5, no. 1 (January 1, 2017): 3–13.
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    • Barroso, Michael Coll, Frank Kramer, Stephen J. Greene, Daniel Scheyer, Till Köhler, Martin Karoff, Melchior Seyfarth, Mihai Gheorghiade, and Wilfried Dinh. “Serum insulin-like growth factor-1 and its binding protein-7: potential novel biomarkers for heart failure with preserved ejection fraction.” Bmc Cardiovascular Disorders 16, no. 1 (October 21, 2016): 199. https://doi.org/10.1186/s12872-016-0376-2.
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    • Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Marco Metra, Javed Butler, Andrew P. Ambrosy, Justin A. Ezekowitz, et al. “Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Circ Heart Fail 9, no. 9 (September 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.002986.
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    • Vaduganathan, Muthiah, Ravi B. Patel, Stephen J. Greene, and Mihai Gheorghiade. “Targeting the vulnerable phase of heart failure: initiate novel therapies in stable patients prior to hospitalization.” European Journal of Heart Failure 18, no. 9 (September 2016): 1190–92. https://doi.org/10.1002/ejhf.598.
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    • Chioncel, Ovidiu, Sean P. Collins, Stephen J. Greene, Andrew P. Ambrosy, Muthiah Vaduganathan, Cezar Macarie, Javed Butler, and Mihai Gheorghiade. “Natriuretic peptide-guided management in heart failure.” Journal of Cardiovascular Medicine (Hagerstown, Md.) 17, no. 8 (August 2016): 556–68. https://doi.org/10.2459/jcm.0000000000000329.
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    • Temporelli, P. L., S. Buda, and S. J. Greene. “Role of omega-3 polyunsaturated fatty acids after acute coronary syndrome.” Giornale Italiano Di Cardiologia 17, no. 7 (July 1, 2016): 3S-10S.
    • Temporelli, Pier Luigi, Stefano Buda, and Stephen J. Greene. “[Role of omega-3 polyunsaturated fatty acids after acute coronary syndrome].” Giornale Italiano Di Cardiologia (2006) 17, no. 7 Suppl 1 (July 2016): 3–10. https://doi.org/10.1714/2336.25080.
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    • Mentz, Robert J., Lothar Roessig, Barry H. Greenberg, Naoki Sato, Kaori Shinagawa, Daniel Yeo, Bernard W. K. Kwok, et al. “Heart Failure Clinical Trials in East and Southeast Asia: Understanding the Importance and Defining the Next Steps.” Jacc Heart Fail 4, no. 6 (June 2016): 419–27. https://doi.org/10.1016/j.jchf.2016.01.013.
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    • Ambrosy, Andrew P., Hassan Khan, James E. Udelson, Robert J. Mentz, Ovidiu Chioncel, Stephen J. Greene, Muthiah Vaduganathan, et al. “Changes in Dyspnea Status During Hospitalization and Postdischarge Health-Related Quality of Life in Patients Hospitalized for Heart Failure: Findings From the EVEREST Trial.” Circ Heart Fail 9, no. 5 (May 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002458.
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    • Gheorghiade, Mihai, Christopher J. Larson, Sanjiv J. Shah, Stephen J. Greene, John G. F. Cleland, Wilson S. Colucci, Preston Dunnmon, et al. “Developing New Treatments for Heart Failure: Focus on the Heart.” Circ Heart Fail 9, no. 5 (May 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002727.
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    • Vaduganathan, Muthiah, Catherine N. Marti, Robert J. Mentz, Stephen J. Greene, Andrew P. Ambrosy, Haris P. Subacius, Gregg C. Fonarow, et al. “Serum Osmolality and Postdischarge Outcomes After Hospitalization for Heart Failure.” Am J Cardiol 117, no. 7 (April 1, 2016): 1144–50. https://doi.org/10.1016/j.amjcard.2015.12.059.
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    • Ambrosy, Andrew P., Adrian F. Hernandez, Paul W. Armstrong, Javed Butler, Allison Dunning, Justin A. Ezekowitz, G Michael Felker, et al. “The clinical course of health status and association with outcomes in patients hospitalized for heart failure: insights from ASCEND-HF.” Eur J Heart Fail 18, no. 3 (March 2016): 306–13. https://doi.org/10.1002/ejhf.420.
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    • Samman Tahhan, Ayman, Muthiah Vaduganathan, Anita Kelkar, Vasiliki V. Georgiopoulou, Andreas P. Kalogeropoulos, Stephen J. Greene, Gregg C. Fonarow, Mihai Gheorghiade, and Javed Butler. “Trends in Heart Failure Clinical Trials From 2001-2012.” Journal of Cardiac Failure 22, no. 3 (March 2016): 171–79. https://doi.org/10.1016/j.cardfail.2015.06.014.
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    • Cook, Thomas D., Stephen J. Greene, Andreas P. Kalogeropoulos, Gregg C. Fonarow, Ryan Zea, Karl Swedberg, Faiez Zannad, et al. “Temporal Changes in Postdischarge Mortality Risk After Hospitalization for Heart Failure (from the EVEREST Trial).” The American Journal of Cardiology 117, no. 4 (February 2016): 611–16. https://doi.org/10.1016/j.amjcard.2015.11.050.
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    • Greene, Stephen J., Pier Luigi Temporelli, Umberto Campia, Muthiah Vaduganathan, Luca Degli Esposti, Stefano Buda, Chiara Veronesi, Javed Butler, and Savina Nodari. “Effects of Polyunsaturated Fatty Acid Treatment on Postdischarge Outcomes After Acute Myocardial Infarction.” The American Journal of Cardiology 117, no. 3 (February 2016): 340–46. https://doi.org/10.1016/j.amjcard.2015.10.050.
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    • Greene, Stephen J., Hani N. Sabbah, Javed Butler, Adriaan A. Voors, Barbara E. Albrecht-Küpper, Hans-Dirk Düngen, Wilfried Dinh, and Mihai Gheorghiade. “Partial adenosine A1 receptor agonism: a potential new therapeutic strategy for heart failure.” Heart Failure Reviews 21, no. 1 (January 2016): 95–102. https://doi.org/10.1007/s10741-015-9522-7.
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    • Gheorghiade, Mihai, Stephen J. Greene, Javed Butler, Gerasimos Filippatos, Carolyn S. P. Lam, Aldo P. Maggioni, Piotr Ponikowski, et al. “Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial.” Jama 314, no. 21 (December 2015): 2251–62. https://doi.org/10.1001/jama.2015.15734.
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    • Chioncel, Ovidiu, Sean P. Collins, Stephen J. Greene, Andrew P. Ambrosy, Muthiah Vaduganathan, Cezar Macarie, Javed Butler, and Mihai Gheorghiade. “Natriuretic peptide-guided management in heart failure.” Journal of Cardiovascular Medicine (Hagerstown, Md.), November 7, 2015.
    • Butler, Javed, Mihai Gheorghiade, Anita Kelkar, Gregg C. Fonarow, Stefan Anker, Stephen J. Greene, Lampros Papadimitriou, et al. “In-hospital worsening heart failure.” Eur J Heart Fail 17, no. 11 (November 2015): 1104–13. https://doi.org/10.1002/ejhf.333.
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    • Ambrosy, Andrew P., Robert J. Mentz, Arun Krishnamoorthy, Stephen J. Greene, and Harry W. Severance. “Identifying Barriers and Practical Solutions to Conducting Site-Based Research in North America: Exploring Acute Heart Failure Trials As a Case Study.” Heart Fail Clin 11, no. 4 (October 2015): 581–89. https://doi.org/10.1016/j.hfc.2015.07.002.
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    • Greene, Stephen J., Lora AlKhawam, Andrew P. Ambrosy, Muthiah Vaduganathan, and Robert J. Mentz. “Hospitalized Heart Failure in the United States: Lessons Learned from Clinical Trial Populations.” Heart Fail Clin 11, no. 4 (October 2015): 591–601. https://doi.org/10.1016/j.hfc.2015.07.003.
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    • Greene, Stephen J., and Gregg C. Fonarow. “Insulin resistance in heart failure: widening the divide between reduced and preserved ejection fraction?” European Journal of Heart Failure 17, no. 10 (October 2015): 991–93. https://doi.org/10.1002/ejhf.337.
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    • Khan, Hassan, Stephen J. Greene, Gregg C. Fonarow, Andreas P. Kalogeropoulos, Andrew P. Ambrosy, Aldo P. Maggioni, Faiez Zannad, et al. “Length of hospital stay and 30-day readmission following heart failure hospitalization: insights from the EVEREST trial.” European Journal of Heart Failure 17, no. 10 (October 2015): 1022–31. https://doi.org/10.1002/ejhf.282.
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    • Greene, Stephen J., and Mihai Gheorghiade. “Same protocol, different continents, different patients: should we continue to conduct global heart failure trials?” European Journal of Heart Failure 17, no. 9 (September 2015): 875–78. https://doi.org/10.1002/ejhf.335.
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    • Harinstein, Matthew E., Javed Butler, Stephen J. Greene, Gregg C. Fonarow, Norman L. Stockbridge, Christopher M. O’Connor, Marc A. Pfeffer, et al. “Site selection for heart failure clinical trials in the USA.” Heart Fail Rev 20, no. 4 (July 2015): 375–83. https://doi.org/10.1007/s10741-015-9473-z.
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    • Vaduganathan, Muthiah, Ayman S. Tahhan, Stephen J. Greene, Anita A. Kelkar, Vasiliki V. Georgiopoulou, Andreas P. Kalogeropoulos, Gregg C. Fonarow, Mihai Gheorghiade, and Javed Butler. “Contemporary cardiovascular device clinical trials (trends and patterns 2001 to 2012).” The American Journal of Cardiology 116, no. 2 (July 2015): 307–12. https://doi.org/10.1016/j.amjcard.2015.03.062.
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    • Vaduganathan, Muthiah, Javed Butler, Lothar Roessig, Gregg C. Fonarow, Stephen J. Greene, Marco Metra, Gadi Cotter, et al. “Clinical trials in hospitalized heart failure patients: targeting interventions to optimal phenotypic subpopulations.” Heart Failure Reviews 20, no. 4 (July 2015): 393–400. https://doi.org/10.1007/s10741-015-9485-8.
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    • Greene, Stephen J., Gregg C. Fonarow, Scott D. Solomon, Haris Subacius, Aldo P. Maggioni, Michael Böhm, Eldrin F. Lewis, Faiez Zannad, Mihai Gheorghiade, and Mihai ASTRONAUT Investigators and Coordinators. “Global variation in clinical profile, management, and post-discharge outcomes among patients hospitalized for worsening chronic heart failure: findings from the ASTRONAUT trial.” European Journal of Heart Failure 17, no. 6 (June 2015): 591–600. https://doi.org/10.1002/ejhf.280.
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    • Echouffo-Tcheugui, Justin B., Stephen J. Greene, Lampros Papadimitriou, Faiez Zannad, Clyde W. Yancy, Mihai Gheorghiade, and Javed Butler. “Population risk prediction models for incident heart failure: a systematic review.” Circulation. Heart Failure 8, no. 3 (May 2015): 438–47. https://doi.org/10.1161/circheartfailure.114.001896.
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    • Greene, Stephen J., Gregg C. Fonarow, and Javed Butler. “REPORT-HF: the unique blend of global heart failure registry and longitudinal cohort study.” European Journal of Heart Failure 17, no. 5 (May 2015): 472–74. https://doi.org/10.1002/ejhf.264.
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    • Greene, Stephen J., Gregg C. Fonarow, Muthiah Vaduganathan, Sadiya S. Khan, Javed Butler, and Mihai Gheorghiade. “The vulnerable phase after hospitalization for heart failure.” Nature Reviews. Cardiology 12, no. 4 (April 2015): 220–29. https://doi.org/10.1038/nrcardio.2015.14.
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    • Greene, Stephen J., and Mihai Gheorghiade. “Reply: considerations for drug development for heart failure.” Journal of the American College of Cardiology 65, no. 10 (March 2015): 1061–62. https://doi.org/10.1016/j.jacc.2014.11.064.
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    • Maisel, Alan, Yang Xue, Stephen J. Greene, Peter S. Pang, James L. Januzzi, Ileana L. Piña, Christopher DeFilippi, and Javed Butler. “The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure.” Journal of Cardiac Failure 21, no. 3 (March 2015): 233–39. https://doi.org/10.1016/j.cardfail.2014.11.009.
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    • Dei Cas, Alessandra, Sadiya S. Khan, Javed Butler, Robert J. Mentz, Robert O. Bonow, Angelo Avogaro, Diethelm Tschoepe, et al. “Impact of diabetes on epidemiology, treatment, and outcomes of patients with heart failure.” Jacc Heart Fail 3, no. 2 (February 2015): 136–45. https://doi.org/10.1016/j.jchf.2014.08.004.
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    • Greene, Stephen J., Aldo P. Maggioni, Gregg C. Fonarow, Scott D. Solomon, Michael Böhm, Albert Kandra, Margaret F. Prescott, et al. “Clinical profile and prognostic significance of natriuretic peptide trajectory following hospitalization for worsening chronic heart failure: findings from the ASTRONAUT trial.” European Journal of Heart Failure 17, no. 1 (January 2015): 98–108. https://doi.org/10.1002/ejhf.201.
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    • Parrinello, Gaspare, Stephen J. Greene, Daniele Torres, Michael Alderman, Joseph Vincent Bonventre, Pietro Di Pasquale, Luna Gargani, et al. “Water and sodium in heart failure: a spotlight on congestion.” Heart Failure Reviews 20, no. 1 (January 2015): 13–24. https://doi.org/10.1007/s10741-014-9438-7.
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    • Vaduganathan, Muthiah, Robert J. Mentz, Stephen J. Greene, Michele Senni, Naoki Sato, Savina Nodari, Javed Butler, and Mihai Gheorghiade. “Combination decongestion therapy in hospitalized heart failure: loop diuretics, mineralocorticoid receptor antagonists and vasopressin antagonists.” Expert Rev Cardiovasc Ther 13, no. 7 (2015): 799–809. https://doi.org/10.1586/14779072.2015.1053872.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Andrew P. Ambrosy, Robert J. Mentz, Haris P. Subacius, Ovidiu Chioncel, Aldo P. Maggioni, et al. “Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial).” Am J Cardiol 114, no. 11 (December 1, 2014): 1713–21. https://doi.org/10.1016/j.amjcard.2014.09.008.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Gregg C. Fonarow, Adriaan A. Voors, Javed Butler, and Mihai Gheorghiade. “Hemoconcentration-guided diuresis in heart failure.” The American Journal of Medicine 127, no. 12 (December 2014): 1154–59. https://doi.org/10.1016/j.amjmed.2014.06.009.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Andrew P. Ambrosy, and Mihai Gheorghiade. “Lipids, statins, and clinical outcomes in heart failure: rethinking the data.” Heart Fail Rev 19, no. 6 (November 2014): 695–98. https://doi.org/10.1007/s10741-014-9423-1.
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    • Greene, Stephen J., and Mihai Gheorghiade. “Matching mechanism of death with mechanism of action: considerations for drug development for hospitalized heart failure.” Journal of the American College of Cardiology 64, no. 15 (October 2014): 1599–1601. https://doi.org/10.1016/j.jacc.2014.06.1199.
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    • Vaduganathan, Muthiah, Alessandra Dei Cas, Robert J. Mentz, Stephen J. Greene, Sadiya Khan, Haris P. Subacius, Ovidiu Chioncel, et al. “Mineralocorticoid receptor antagonist use in hospitalized patients with heart failure, reduced ejection fraction, and diabetes mellitus (from the EVEREST Trial).” Am J Cardiol 114, no. 5 (September 1, 2014): 743–50. https://doi.org/10.1016/j.amjcard.2014.05.064.
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    • Greene, Stephen J., Ami N. Shah, Javed Butler, Andrew P. Ambrosy, Stefan D. Anker, Ovidiu Chioncel, Sean P. Collins, et al. “Designing effective drug and device development programs for hospitalized heart failure: a proposal for pretrial registries.” Am Heart J 168, no. 2 (August 2014): 142–49. https://doi.org/10.1016/j.ahj.2014.05.009.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Gregg C. Fonarow, Robert O. Bonow, Javed Butler, and Mihai Gheorghiade. “Coronary artery disease in patients with heart failure: incidental, coincidental, or a target for therapy?” The American Journal of Medicine 127, no. 7 (July 2014): 574–78. https://doi.org/10.1016/j.amjmed.2014.01.041.
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    • Vaduganathan, Muthiah, and Stephen J. Greene. “Influence of Chronic Kidney Disease on Warfarin Therapy for Atrial Fibrillation.” Jama 311, no. 24 (June 25, 2014): 2541–2541. https://doi.org/10.1001/jama.2014.5576.
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    • Mentz, Robert J., Stephen J. Greene, Andrew P. Ambrosy, Muthiah Vaduganathan, Haris P. Subacius, Karl Swedberg, Aldo P. Maggioni, et al. “Clinical profile and prognostic value of anemia at the time of admission and discharge among patients hospitalized for heart failure with reduced ejection fraction: findings from the EVEREST trial.” Circ Heart Fail 7, no. 3 (May 2014): 401–8. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000840.
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    • Greene, Stephen J., Lora Alkhawam, and Muthiah Vaduganathan. “Dual Antiplatelet Therapy After Stent Implantation.” Jama 311, no. 14 (April 9, 2014): 1446–1446. https://doi.org/10.1001/jama.2014.2092.
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    • Ambrosy, Andrew P., Gregg C. Fonarow, Javed Butler, Ovidiu Chioncel, Stephen J. Greene, Muthiah Vaduganathan, Savina Nodari, et al. “The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries.” J Am Coll Cardiol 63, no. 12 (April 1, 2014): 1123–33. https://doi.org/10.1016/j.jacc.2013.11.053.
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    • Gheorghiade, Mihai, Muthiah Vaduganathan, Stephen J. Greene, Robert J. Mentz, Kirkwood F. Adams, Stefan D. Anker, Malcolm Arnold, et al. “Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions.” Heart Fail Rev 19, no. 2 (March 2014): 135–52. https://doi.org/10.1007/s10741-012-9361-8.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Javed Butler, and Mihai Gheorghiade. “Endpoints for diuresis: are we there yet?” Journal of the American College of Cardiology 63, no. 8 (March 2014): 838–39. https://doi.org/10.1016/j.jacc.2013.04.108.
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    • Greene, Stephen J., Muthiah Vaduganathan, Jane E. Wilcox, Matthew E. Harinstein, Aldo P. Maggioni, Haris Subacius, Faiez Zannad, et al. “The prognostic significance of heart rate in patients hospitalized for heart failure with reduced ejection fraction in sinus rhythm: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study With Tolvaptan) trial.” Jacc. Heart Failure 1, no. 6 (December 2, 2013): 488–96. https://doi.org/10.1016/j.jchf.2013.08.005.
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    • Greene, Stephen J., Mihai Gheorghiade, Muthiah Vaduganathan, Andrew P. Ambrosy, Robert J. Mentz, Haris Subacius, Aldo P. Maggioni, et al. “Haemoconcentration, renal function, and post-discharge outcomes among patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial.” Eur J Heart Fail 15, no. 12 (December 2013): 1401–11. https://doi.org/10.1093/eurjhf/hft110.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Andrew P. Ambrosy, Robert J. Mentz, Gregg C. Fonarow, Faiez Zannad, Aldo P. Maggioni, et al. “Relation of serum magnesium levels and postdischarge outcomes in patients hospitalized for heart failure (from the EVEREST Trial).” Am J Cardiol 112, no. 11 (December 1, 2013): 1763–69. https://doi.org/10.1016/j.amjcard.2013.07.020.
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    • Gheorghiade, Mihai, Muthiah Vaduganathan, Gregg C. Fonarow, Stephen J. Greene, Barry H. Greenberg, Peter P. Liu, Barry M. Massie, et al. “Anticoagulation in heart failure: current status and future direction.” Heart Failure Reviews 18, no. 6 (November 2013): 797–813. https://doi.org/10.1007/s10741-012-9343-x.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Javed Butler, Hani N. Sabbah, Eduard Shantsila, Gregory Y. H. Lip, and Mihai Gheorghiade. “The immunological axis in heart failure: importance of the leukocyte differential.” Heart Failure Reviews 18, no. 6 (November 2013): 835–45. https://doi.org/10.1007/s10741-012-9352-9.
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    • Maggioni, Aldo P., Stephen J. Greene, Gregg C. Fonarow, Michael Böhm, Faiez Zannad, Scott D. Solomon, Eldrin F. Lewis, et al. “Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial.” European Heart Journal 34, no. 40 (October 2013): 3117–27. https://doi.org/10.1093/eurheartj/eht342.
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    • Gheorghiade, Mihai, Stephen J. Greene, Piotr Ponikowski, Aldo P. Maggioni, Jerzy Korewicki, Cezar Macarie, Marco Metra, et al. “Haemodynamic effects, safety, and pharmacokinetics of human stresscopin in heart failure with reduced ejection fraction.” European Journal of Heart Failure 15, no. 6 (June 2013): 679–89. https://doi.org/10.1093/eurjhf/hft023.
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    • Gheorghiade, Mihai, Kanan Patel, Gerasimos Filippatos, Stefan D. Anker, Dirk J. van Veldhuisen, John G. F. Cleland, Marco Metra, et al. “Effect of oral digoxin in high-risk heart failure patients: a pre-specified subgroup analysis of the DIG trial.” European Journal of Heart Failure 15, no. 5 (May 2013): 551–59. https://doi.org/10.1093/eurjhf/hft010.
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    • Gheorghiade, Mihai, Catherine N. Marti, Hani N. Sabbah, Lothar Roessig, Stephen J. Greene, Michael Böhm, John C. Burnett, et al. “Soluble guanylate cyclase: a potential therapeutic target for heart failure.” Heart Failure Reviews 18, no. 2 (March 2013): 123–34. https://doi.org/10.1007/s10741-012-9323-1.
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    • Gheorghiade, Mihai, Michael Böhm, Stephen J. Greene, Gregg C. Fonarow, Eldrin F. Lewis, Faiez Zannad, Scott D. Solomon, et al. “Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial.” Jama 309, no. 11 (March 2013): 1125–35. https://doi.org/10.1001/jama.2013.1954.
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    • Greene, Stephen J., Muthiah Vaduganathan, Laura Lupi, Andrew P. Ambrosy, Robert J. Mentz, Marvin A. Konstam, Savina Nodari, et al. “Prognostic significance of serum total cholesterol and triglyceride levels in patients hospitalized for heart failure with reduced ejection fraction (from the EVEREST Trial).” Am J Cardiol 111, no. 4 (February 15, 2013): 574–81. https://doi.org/10.1016/j.amjcard.2012.10.042.
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    • Ambrosy, Andrew P., Muthiah Vaduganathan, Robert J. Mentz, Stephen J. Greene, Haris Subačius, Marvin A. Konstam, Aldo P. Maggioni, Karl Swedberg, and Mihai Gheorghiade. “Clinical profile and prognostic value of low systolic blood pressure in patients hospitalized for heart failure with reduced ejection fraction: insights from the Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST) trial.” Am Heart J 165, no. 2 (February 2013): 216–25. https://doi.org/10.1016/j.ahj.2012.11.004.
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    • Vaduganathan, Muthiah, Stephen J. Greene, Andrew P. Ambrosy, Mihai Gheorghiade, and Javed Butler. “The disconnect between phase II and phase III trials of drugs for heart failure.” Nature Reviews. Cardiology 10, no. 2 (February 2013): 85–97. https://doi.org/10.1038/nrcardio.2012.181.
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    • Greene, Stephen J., Mihai Gheorghiade, Barry A. Borlaug, Burkert Pieske, Muthiah Vaduganathan, John C. Burnett, Lothar Roessig, et al. “The cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fraction.” Journal of the American Heart Association 2, no. 6 (January 2013): e000536. https://doi.org/10.1161/JAHA.113.000536.
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    • Lanfear, David E., Hani N. Sabbah, Steven R. Goldsmith, Stephen J. Greene, Andrew P. Ambrosy, Angela J. Fought, Mary J. Kwasny, et al. “Association of arginine vasopressin levels with outcomes and the effect of V2 blockade in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial.” Circ Heart Fail 6, no. 1 (January 2013): 47–52. https://doi.org/10.1161/CIRCHEARTFAILURE.112.970012.
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    • Greene, Stephen J., Matthew E. Harinstein, Muthiah Vaduganathan, Haris Subačius, Marvin A. Konstam, Faiez Zannad, Aldo P. Maggioni, et al. “Prognostic value of monocyte count in patients hospitalized for heart failure with reduced ejection fraction (from the EVEREST Trial).” The American Journal of Cardiology 110, no. 11 (December 2012): 1657–62. https://doi.org/10.1016/j.amjcard.2012.07.035.
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    • Vaduganathan, Muthiah, Andrew P. Ambrosy, Stephen J. Greene, Robert J. Mentz, Haris P. Subacius, Aldo P. Maggioni, Karl Swedberg, et al. “Predictive value of low relative lymphocyte count in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial.” Circ Heart Fail 5, no. 6 (November 2012): 750–58. https://doi.org/10.1161/CIRCHEARTFAILURE.112.970525.
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    • Gheorghiade, Mihai, Stephen J. Greene, Gerasimos Filippatos, Erland Erdmann, Roberto Ferrari, Phillip D. Levy, Aldo Maggioni, Christina Nowack, Alexandre Mebazaa, and Alexandre COMPOSE Investigators and Coordinators. “Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes.” European Journal of Heart Failure 14, no. 9 (September 2012): 1056–66. https://doi.org/10.1093/eurjhf/hfs093.
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  • Conference Papers

    • Gheorghiade, Mihai, Aldo P. Maggioni, Carolyn Lam, Eliana Samano, Elisabeth Kraigher-Krainer, Gerasimos Filippatos, Javed Butler, et al. “Oral sGC Stimulator Vericiguat in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction - The SOluble guanylate Cyclase stimulatoR in heArT failurE patientS With REDUCED EF (SOCRATES-REDUCED) Study.” In Circulation, 132:2268–69. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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    • Greene, Stephen John, Muthiah Vaduganathan, Andrew Ambrosy, Marvin Konstam, Haris Subacius, Aldo Maggioni, Robert Mentz, Savina Nodari, Javed Butler, and Mihai Gheorghiade. “INFLUENCE OF URIC ACID LEVEL IN PATIENTS HOSPITALIZED FOR HEART FAILURE WITH REDUCED EJECTION FRACTION: INSIGHTS FROM THE EVEREST TRIAL.” In Journal of the American College of Cardiology, 61:E618–E618. Elsevier BV, 2013. https://doi.org/10.1016/s0735-1097(13)60618-x.
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