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Stephen D Mague

Assistant Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
3209, Bryan Research Building; Rm 361, Durham, NC 27710
3209, Bryan Research Building; Rm 421, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor in Psychiatry and Behavioral Sciences · 2021 - Present Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences

Recent Publications


Electome network factors: Capturing emotional brain networks related to health and disease.

Journal Article Cell Rep Methods · January 22, 2024 Therapeutic development for mental disorders has been slow despite the high worldwide prevalence of illness. Unfortunately, cellular and circuit insights into disease etiology have largely failed to generalize across individuals that carry the same diagnos ... Full text Link to item Cite

Prenatal environmental stressors impair postnatal microglia function and adult behavior in males.

Journal Article Cell Rep · August 2, 2022 Gestational exposure to environmental toxins and socioeconomic stressors is epidemiologically linked to neurodevelopmental disorders with strong male bias, such as autism. We model these prenatal risk factors in mice by co-exposing pregnant dams to an envi ... Full text Link to item Cite

Brain-wide electrical dynamics encode individual appetitive social behavior.

Journal Article Neuron · May 18, 2022 The architecture whereby activity across many brain regions integrates to encode individual appetitive social behavior remains unknown. Here we measure electrical activity from eight brain regions as mice engage in a social preference assay. We then use ma ... Full text Link to item Cite
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Recent Grants


Precise neural circuit editing using engineered electrical synapses

ResearchResearch Scientist · Awarded by National Institutes of Health · 2022 - 2027

Regulating brain networks that mediate depressive states

ResearchCo Investigator · Awarded by Hope for Depression Research Foundation · 2023 - 2026

MULTIREGIONAL ELECTRICAL ENCODING OF SOCIAL AGGRESSION

ResearchCo Investigator · Awarded by National Institute of Mental Health · 2021 - 2026

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Education, Training & Certifications


University of Pennsylvania · 2011 Ph.D.