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Stephen Lowe Young

Professor Emeritus of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
2301 Erwin Road, Durham, NC 27710
A5013 VAMC, Durham, NC 27710

Overview


Although I no longer am actively involved in research, my prior work experience is given below:

My laboratory work focussed upon the cell biology of the lung epithelium: during development, including the processes of branching morphogenesis and second, during the maintenence of lung surface forces through the epithelial secretion known as surfactant.

We emphasized a morphologic approach utilizing the full range of ultrastructural techniques, supplemented with molecular biologic techniques that allow structure function correlations.

I have been involved in clinical trials examining vaccination against influenza and examining the value of inhaled steroids, both experiments in patients with COPD.

I am recognized mainly for work in surfactant and lung development.

Lung surfactant; alveolar type II cell; branching morphogenesis; lung development

Current Appointments & Affiliations


Professor Emeritus of Medicine · 2016 - Present Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine

Recent Publications


The opprobrium of Big Tobacco.

Journal Article Am J Respir Crit Care Med · May 1, 2012 Full text Link to item Cite

Impact of a winter respiratory virus season on patients with COPD and association with influenza vaccination.

Journal Article Chest · October 2006 BACKGROUND: We assessed the effects of an influenza season on patients with COPD. Data from 2,215 veterans in a multicenter, randomized, double-blind influenza vaccine efficacy study were analyzed for changes in spirometric and functional status, comparing ... Full text Link to item Cite
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Recent Grants


Long-term Oxygen Treatment Trial (LOTT) - Regional Clinical Centers (RCCs)

ResearchCo Investigator · Awarded by National Institutes of Health · 2006 - 2012

Leukocyte Chemokine Blockade to Preserve LungDevelopment

ResearchConsultant · Awarded by National Institutes of Health · 2002 - 2006

Regulation of ryanodine receptor by nitrogen oxides

ResearchCollaborator · Awarded by National Institutes of Health · 1999 - 2004

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Education, Training & Certifications


University of California San Francisco, School of Medicine · 1968 M.D.