Current Appointments & Affiliations
Professor in Biostatistics & Bioinformatics
·
2023 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Recent Publications
Benchmarking 13 tools for mutational signature attribution, including a new and improved algorithm.
Journal Article Brief Bioinform · November 22, 2024 Mutational signatures are characteristic patterns of mutations caused by endogenous mutational processes or by exogenous mutational exposures. There has been little benchmarking of approaches for determining which signatures are present in a sample and est ... Full text Link to item CiteMolecular profiling reveals novel therapeutic targets and clonal evolution in ovarian clear cell carcinoma.
Journal Article BMC Cancer · November 14, 2024 BACKGROUND: Ovarian clear cell carcinoma (OCCC) has a disproportionately high incidence among women in East Asia. Patients diagnosed with OCCC tend to experience worse clinical outcomes than those with high-grade serous carcinoma (HGSC) at advanced stages. ... Full text Link to item CiteOncogene-Driven Non-Small Cell Lung Cancers in Patients with a History of Smoking Lack Smoking-Induced Mutations.
Journal Article Cancer Res · June 14, 2024 UNLABELLED: Non-small cell lung cancers (NSCLC) in nonsmokers are mostly driven by mutations in the oncogenes EGFR, ERBB2, and MET and fusions involving ALK and RET. In addition to occurring in nonsmokers, alterations in these "nonsmoking-related oncogenes ... Full text Link to item CiteRecent Grants
The Molecular Genetics of High Myopia
ResearchCollaborator · Awarded by National Institutes of Health · 2003 - 2014Metabolic Signatures for Alzheimer's Disease
ResearchResearcher · Awarded by National Institutes of Health · 2007 - 2011View All Grants
Education, Training & Certifications
New York University ·
1993
Ph.D.